Stan Gronthos

Research Interests

Cancer Biology and Clinical Oncology Musculoskeletal Health Oral Health Innovative Therapeutics

Professor Stan Gronthos

Emeritus Professor

School of Pharmacy and Biomedical Science

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Prof. Stan Gronthos' research specialty is in stem cell biology and regenerative medicine. He is Founder and Head of the Mesenchymal Stem Cell Laboratory in the Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide. In 2018, Prof Gronthos was awarded a Fellow of the American Society of Bone and Mineral Research. In 2014, the Mesenchymal Stem Cell Laboratory moved to the South Australian Health and Medical Research Institute (SAHMRI) on North Terrace, adjacent to the new Royal Adelaide Hospital site.

Research Interests

The focus of the Mesenchymal Stem Cell Laboratory is to investigate the origin and biological properties of different postnatal mesenchymal stem cell (MSC) populations, that give rise to supportive connective tissues such as myelosupportive stroma, adipose tissue, smooth muscle, cardiac muscle, bone, cartilage, ligament, cementum and dentin. Our work seeks to identify critical genes and epigenetic factors that regulate MSC self-renewal, proliferation and differentiation. In addition, research efforts have focused on identifying the factors central to MSC mediated regulation of haematopiesis, angiogenesis and immune cell modulation. Importantly, many of these molecular processes are considered underlying causes of chronic diseases and tumour cell development. Together with Prof. Andrew Zannettino and our commercial partner (Mesoblast Ltd), our basic research activities have progressed into Phase II/III human clinical trails for orthopaedic, cardiovascular, cancer and immune based indications. Our continuing research into the basic properties of MSC will help develop more effective and safer stem cell based therapeutic options in the future for a wide variety of clinical diseases and conditions.

PATENTS:

  1. Inventors: Gronthos S., Zannettino A.C.W., Simmons P.J., Patent: Mesenchymal Precursor Cells WO2001/04268A1. Applicant: Medvet Science Pty Ltd, Adelaide, S.A., Australia. 1999, licensed to Angioblast Systems Inc., New York, NY. Granted in USA, AUS, CA, ES, EP.
  2. Inventors: Gronthos S., Robey P.G., Miura M., and Shi S. Postnatal stem cells and uses thereof. U.S. Patent Application No. PCT/US2003/012276. WO2004/094588A2. Applicant: National Institutes of Health, Bethesda, Maryland USA. Granted in the USA, EP, ES, CA.
  3. Inventors: Gronthos S., Robey P.G., and Shi S. U.S. "Adult human dental pulp stem cells In Vitro and In Vivo". Provisional Patent Application No. 60/219,989, WO2002/007679A2. Applicant: National Institutes of Health, Bethesda, Maryland, USA. Granted in the USA, AUS, CA, ES, EP.
  4. Inventors: Stan Gronthos, Songtao Shi and Andrew Zannettino.  Perivascular Mesenchymal Precursor Cells. Provisional application PCT/AU2004/000416, WO2004/085630A1. Applicants: Medvet Science Pty Ltd, Adelaide, S.A., Australia and Angioblast Inc. New York, NY. Granted in USA, AUS, CA, CN.
  5. Inventors: Stan Gronthos and Andrew Zannettino Perivascular Mesenchymal Precursor Cell Induced Blood Vessel Formation (Neovascularization) 28-Mar-2003 Provisional application PCT Application No PCT/AU2004/000417, WO2004/084921A1, Medvet Science Pty Ltd, Adelaide, S.A., Australia and Angioblast Inc. Granted in USA, AUS, EP, CA, CN, ES.
  6. Inventors: Stan Gronthos and Andrew Zannettino. Multipotential expanded Mesenchymal Precursor Cell progeny and uses there off. PCT/AU2005/001445, 24/09/2004, WO2006/032092A1. Applicant: Angioblast Systems Inc. New York, NY. Granted in US, AU, EP, CN.
  7. Inventors: Stan Gronthos, Andrew Zannettino, Paul Simmons. Isolation of adult multipotential Cells by tissue non-specific alkaline phosphotase. PCT/AU2006/000494; W02006/108229A1. Applicant: Angioblast Systems Inc. New York, NY. Granted in USA, AU, EP, CA, HK.
  8. Inventors: Stan Gronthos and Andrew Zannettino. Method of enhancing proliferation and/or survival of mesenchymal precursor cells. PCT/AU2005/000953, WO2006/032075A1. Applicant: Angioblast Systems Inc. New York, NY. Granted in the USA, AUS, CN.
  9. Inventors: Gronthos S, Koblar SA, Arthur A. International (PCT) Patent Application (PCT/AU2008/001286; WO2009/026653A8) “Neuroplasticity Assay”. Applicant: MedVet/ Science Pty. Ltd/ Adelaide Research & Innovation Pty. Ltd.
  10. Inventors: Stan Gronthos and Andrew Zannettino. Monoclonal antibody STRO-4 (Provisional; US 61/189,349) 18/08/2008; PCT WO2010/019997A1. Applicant: Angioblast Systems Inc. New York, NY. Granted in AUS, USA.
  11. Inventors: Gronthos S, Koblar SA, Arthur A. Patent Application WO2012/162758A1, US201161493057P filed on 3 June 2011 entitled “Method Of Treating The Effects Of Stroke”; Applicant Mesoblast Pty Ltd. Granted in AUS.
  12. Inventors: Gronthos S, Zannettino ACW and Fitter S. AUS Provisional Patent # 2015902032  filed on 1 June 2015; PCT/AU2016/050438; entitled “Methods and Products for Enriching and  Isolating Stem Cell”; Applicant: Adelaide Research & Innovation Pty. Ltd.
Research Projects Available

Mesenchymal Stem Cell Laboratory, AMS, Medical Sciences

Lab Head, Prof Stan Gronthos

Postnatal mesenchymal stem cells (MSC) derived from connective tissues are capable of developing into multiple cell lineages (myelosupportive stroma, adipocytes, smooth muscle cells, myoblasts, ligament cells, chondrocytes and osteoblasts). Our Lab examines the transcriptional, epigenetic and signalling factors that regulate MSC self-renewal, proliferation, multi-differentiation and immune cell modulation. These molecular processes are being investigated as underlying mechanisms mediating tissue repair, inflammation, tumour cell development and aged related diseases.

http://www.adelaide.edu.au/directory/stan.gronthos

https://researchers.adelaide.edu.au/profile/stan.gronthos

 

Location: Level 5 South SAHMRI

Research project start: Semester 1 and 2 for Hons and Third year placements

Special requirements: HepB vaccination required

 

Projects for 2020

1. Pharmacological targeting of tyrosine kinase receptors and epigenetic modifying enzymes in mesenchymal stem cells to treat cranial bone conditions. (The use of chemical inhibitors to modify bone cell differentiation by mesenchymal stem cells in the cranial sutures to treat craniosynostosis in children).

2. Investigation of the importance of cell-cell communication and cross-talk between bone cells, blood cells and neural cells during skeletal development/ repair. (Investigating the role of the membrane bound contact dependent molecules, Eph/ ephrin, to mediate cell-cell communication and function between bone cells, blood/ immune cells and neural tissue, during development and tissue repair).

3. Investigating the role of epigenetic modifiers to control mesenchymal stem cell self-renewal and cell fate determination in development and tissue repair. (Investigation of the role of histone acetylation and methylation or DNA methylation in mesenchymal stem cell self-renewal and cell fate determination, in the context of skeletal stem cell ageing and bone disease).

 

HDR Projects

1. Pharmacological targeting of tyrosine kinase receptors and epigenetic modifying enzymes in mesenchymal stem cells to treat cranial bone conditions.

2. Investigation of the importance of cell-cell communication and cross-talk between bone cells, blood cells and neural cells during skeletal development/ repair.

6. Histone acetylation and methylation as regulators of mesenchymal stem cell self-renewal and cell fate determination.

5. Examining the role of DNA methylation in skeletal stem cell ageing and bone disease.

 

Hons and Third year placements (Semester 1 and 2 ) Projects

1. Identification of molecular mechanisms controlling cranial bone development in children.

2. Investigating mechanisms of cell-cell communication during tooth formation.

3. Investigation mechanisms of cell-cell communication in bone and cartilage development.

4. Identifying Epigenetic Enzymes involved in the growth and differentiation of bone marrow derived mesenchymal stem cells.

5. Identifying Epigenetic "Readers" involved in mesenchymal stem cell growth and

differentiation.

 

Date Position Institution name
2012 - ongoing Professor in Stem Cell Biology and Regenerative Medicine University of Adelaide

Date Institution name Country Title
1994 - 1988 University of Adelaide Australia PhD

Date Title Institution Country
1999 - 2001 NIH Research Fellow National Institutes of Health United States

Year Citation
2025 Plakhova, N., Panagopoulos, V., Cantley, M. D., Trainor, L. J., Hewett, D. R., Clark, K. C., . . . Vandyke, K. (2025). Age-related mesenchymal stromal cell senescence is associated with progression from MGUS to multiple myeloma.. Leukemia, 39(6), 1464-1475.
DOI Scopus1 WoS3 Europe PMC1
2025 Smith, N., Cakouros, D., Ryan, F. J., Lynn, D. J., Paton, S., Arthur, A., & Gronthos, S. (2025). DNA hydroxymethylases Tet1 and Tet2 regulate bone aging and BMSC metabolism through the IGF-1/ mTOR signalling axis. Stem Cells, 43(8), sxaf026-1-sxaf026-17.
DOI
2025 Nguyen, M. T., Gronthos, S., Zhao, Y., Chandrakanthan, V., Truong, V. K., & Vasilev, K. (2025). Overcoming challenges in cartilage regeneration: The role of chondrogenic inducers. Bioengineering & Translational Medicine, 1-26.
DOI
2024 Gancheva, M. R., Kremer, K., Breen, J., Arthur, A., Hamilton-Bruce, A., Thomas, P., . . . Koblar, S. (2024). Effect of Octamer-Binding Transcription Factor 4 Overexpression on the Neural Induction of Human Dental Pulp Stem Cells. Stem Cell Reviews and Reports, 20(3), 797-815.
DOI Scopus5 WoS3 Europe PMC3
2024 Jenkner, S., Clark, J. M., Gronthos, S., & O’Hare Doig, R. L. (2024). Molars to Medicine: A Focused Review on the Pre-Clinical Investigation and Treatment of Secondary Degeneration following Spinal Cord Injury Using Dental Stem Cells. Cells, 13(10), 31 pages.
DOI Scopus2 WoS1 Europe PMC1
2024 Camp, E., Garcia, L. G., Pribadi, C., Paton, S., Vasilev, K., Anderson, P., & Gronthos, S. (2024). Targeting of C-ROS-1 Activity Using a Controlled Release Carrier to Treat Craniosynostosis in a Preclinical Model of Saethre-Chotzen Syndrome. Journal of Tissue Engineering and Regenerative Medicine, 2024, 8863925-1-8863925-12.
DOI
2024 Campbell, J. M., Habibalahi, A., Agha, A., Handley, S., Knab, A., Xu, X., . . . Goldys, E. M. (2024). Single cell, Label free Characterisation of Human Mesenchymal Stromal cell Stemness and Future Growth Potential by Autofluorescence Multispectral Imaging. Stem Cell Rev Rep, 20(8), 2283-2292.
DOI
2024 Campbell, J. M., Mahbub, S. B., Anwer, A. G., Habibalahi, A., Gronthos, S., Paton, S., . . . Goldys, E. M. (2024). Multispectral Imaging of Collagen, NAD(P)H and Flavin Autofluorescence in Mesenchymal Stem Cells Undergoing Trilineage Differentiation. Cells, 13(20), 1731-1-1731-14.
DOI Europe PMC1
2023 Stoilov, B., Truong, V. K., Gronthos, S., & Vasilev, K. (2023). Noninvasive and Microinvasive Nanoscale Drug Delivery Platforms for Hard Tissue Engineering. ACS Appl Bio Mater, 6(8), 2925-2943.
DOI Scopus4 WoS3 Europe PMC1
2023 Ng, J. Q., Jafarov, T. H., Little, C. B., Wang, T., Ali, A. M., Ma, Y., . . . Mukherjee, S. (2023). Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis. Nature Communications, 14(1), 6909-1-6909-14.
DOI Scopus27 WoS26 Europe PMC26
2023 Smith, N., Shirazi, S., Cakouros, D., & Gronthos, S. (2023). Impact of Environmental and Epigenetic Changes on Mesenchymal Stem Cells during Aging. International Journal of Molecular Sciences, 24(7), 6499.
DOI Scopus14 WoS10 Europe PMC10
2023 Pribadi, C., Cakouros, D., Camp, E., Anderson, P. J., & Gronthos, S. (2023). KDM6A Mediated Regulation of Cranial Frontal Bone Suture Fusion in Mice is Sex-Dependent. Stem Cells and Development, 32(13-14), 398-409.
DOI Scopus4 WoS4 Europe PMC2
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Campbell, D., Paton, S., Thompson-Peach, C. A. L., . . . Hiwase, D. (2022). Senolytic Therapy Can Reverse Senescent Bone Marrow Stroma of Therapy-Related Myeloid Neoplasm. Blood, 140(Supplement 1), 9755-9756.
DOI
2022 Bereza, S., Yong, R., Gronthos, S., Arthur, A., Ranjitkar, S., & Anderson, P. J. (2022). Craniomaxillofacial morphology in a murine model of ephrinB1 conditional deletion in osteoprogenitor cells. Archives of Oral Biology, 137, 1-8.
DOI Scopus4 WoS3 Europe PMC2
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Tran, E. N. H., Campbell, D., Paton, S., . . . Hiwase, D. K. (2022). A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure. Leukemia, 36(11), 2678-2689.
DOI Scopus17 WoS17 Europe PMC17
2021 Futrega, K., Music, E., Robey, P. G., Gronthos, S., Crawford, R., Saifzadeh, S., . . . Doran, M. R. (2021). Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo. Stem Cell Research and Therapy, 12(1), 1-19.
DOI Scopus10 WoS9 Europe PMC8
2021 Arthur, A., & Gronthos, S. (2021). Eph-Ephrin Signaling Mediates Cross-Talk Within the Bone Microenvironment. Frontiers in Cell and Developmental Biology, 9, 19 pages.
DOI Scopus35 WoS33 Europe PMC33
2021 Barker, A. J., Arthur, A., DeNichilo, M. O., Panagopoulos, R., Gronthos, S., Anderson, P. J., . . . Panagopoulos, V. (2021). Plant-derived soybean peroxidase stimulates osteoblast collagen biosynthesis, matrix mineralization, and accelerates bone regeneration in a sheep model. Bone Reports, 14, 101096-1-101096-10.
DOI Scopus3 WoS2 Europe PMC2
2021 Mansouri, N., Al-Sarawi, S., Losic, D., Mazumdar, J., Clark, J., Gronthos, S., & O'Hare Doig, R. (2021). Biodegradable and biocompatible graphene-based scaffolds for functional neural tissue engineering: a strategy approach using dental pulp stem cells and biomaterials. Biotechnology and Bioengineering, 118(11), 4217-4230.
DOI Scopus25 WoS24 Europe PMC13
2021 Prideaux, M., Wright, C. S., Noonan, M. L., Yi, X., Clinkenbeard, E. L., Mevel, E., . . . Thompson, W. R. (2021). Generation of two multipotent mesenchymal progenitor cell lines capable of osteogenic, mature osteocyte, adipogenic, and chondrogenic differentiation. Scientific Reports, 11(1), 22593-1-22593-16.
DOI Scopus14 WoS14 Europe PMC16
2021 Abeynayake, N., Arthur, A., & Gronthos, S. (2021). Crosstalk between skeletal and neural tissues is critical for skeletal health. Bone, 142, 1-13.
DOI Scopus48 WoS47 Europe PMC43
2021 Campbell, J. M., Mahbub, S., Habibalahi, A., Paton, S., Gronthos, S., & Goldys, E. (2021). Ageing human bone marrow mesenchymal stem cells have depleted NAD(P)H and distinct multispectral autofluorescence. GeroScience, 43(2), 859-868.
DOI Scopus14 WoS16 Europe PMC14
2020 Cakouros, D., & Gronthos, S. (2020). Epigenetic regulators of mesenchymal stem/stromal cell lineage determination. Current Osteoporosis Reports, 18(5), 597-605.
DOI Scopus34 WoS31 Europe PMC26
2020 Arthur, A., & Gronthos, S. (2020). Clinical application of bone marrow mesenchymal stem/stromal cells to repair skeletal tissue. International Journal of Molecular Sciences, 21(24), 9759-1-9759--28.
DOI Scopus225 WoS213 Europe PMC160
2020 Ahangar, P., Mills, S. J., Smith, L. E., Gronthos, S., & Cowin, A. J. (2020). Human gingival fibroblast secretome accelerates wound healing through anti-inflammatory and pro-angiogenic mechanisms. npj Regenerative Medicine, 5(1), 1-10.
DOI Scopus67 WoS60 Europe PMC44
2020 Pribadi, C., Camp, E., Cakouros, D., Anderson, P., Glackin, C., & Gronthos, S. (2020). Pharmacological targeting of KDM6A and KDM6B, as a novel therapeutic strategy for treating craniosynostosis in Saethre-Chotzen syndrome. Stem Cell Research and Therapy, 11(1), 529-1-529-14.
DOI Scopus16 WoS16 Europe PMC14
2020 Arthur, A., Paton, S., Zannettino, A. C. W., & Gronthos, S. (2020). Conditional knockout of ephrinB1 in osteogenic progenitors delays the process of endochondral ossification during fracture repair. Bone, 132, 115189-1-115189-10.
DOI Scopus9 WoS7 Europe PMC7
2020 Cheong, C. M., Mrozik, K. M., Hewett, D. R., Bell, E., Panagopoulos, V., Noll, J. E., . . . Vandyke, K. (2020). Twist-1 is upregulated by NSD2 and contributes to tumour dissemination and an epithelial-mesenchymal transition-like gene expression signature in t(4;14)-positive multiple myeloma. Cancer letters, 475, 99-108.
DOI Scopus27 WoS26 Europe PMC25
2020 Black, C., Kanczler, J. M., de Andrés, M. C., White, L. J., Savi, F. M., Bas, O., . . . Oreffo, R. O. C. (2020). Characterisation and evaluation of the regenerative capacity of Stro-4+ enriched bone marrow mesenchymal stromal cells using bovine extracellular matrix hydrogel and a novel biocompatible melt electro-written medical-grade polycaprolactone scaffold.. Biomaterials, 247, 119998.
DOI Scopus34 WoS34 Europe PMC25
2020 H'ng, C. H., Camp, E., Anderson, P. J., Zannettino, A. C. W., & Gronthos, S. (2020). CMTM8 is a suppressor of human mesenchymal stem cell osteogenic differentiation and promoter of proliferation via EGFR signalling. Stem Cells and Development, 29(13), 823-834.
DOI Scopus7 WoS5 Europe PMC5
2020 Cakouros, D., & Gronthos, S. (2020). The changing epigenetic landscape of Mesenchymal Stem/Stromal Cells during aging.. Bone, 137, 1-13.
DOI Scopus28 WoS26 Europe PMC23
2020 Hng, C. H., Camp, E., Anderson, P., Breen, J., Zannettino, A., & Gronthos, S. (2020). HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways. Scientific Reports, 10(1), 1-14.
DOI Scopus16 WoS16 Europe PMC13
2020 Kutyna, M. M., Wee, L. Y. A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2020). Therapy-Related Myeloid Neoplasm Has a Distinct Pro-Inflammatory Bone Marrow Microenvironment and Delayed DNA Damage Repair. Blood, 136(Supplement 1), 37-38.
DOI
2019 Campbell, J. M., Habibalahi, A., Mahbub, S., Gosnell, M., Anwer, A. G., Paton, S., . . . Goldys, E. (2019). Non-destructive, label free identification of cell cycle phase in cancer cells by multispectral microscopy of autofluorescence. BMC Cancer, 19(1), 1-11.
DOI Scopus28 WoS27 Europe PMC29
2019 Cakouros, D., Hemming, S., Gronthos, K., Liu, R., Zannettino, A., Shi, S., & Gronthos, S. (2019). Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination. Epigenetics and Chromatin, 12(1), 20.
DOI Scopus65 WoS61 Europe PMC58
2019 Bartold, M., Gronthos, S., Haynes, D., & Ivanovski, S. (2019). Mesenchymal stem cells and biologic factors leading to bone formation. Journal of Clinical Periodontology, 46(S21), 12-32.
DOI Scopus57 WoS52 Europe PMC46
2019 Cakouros, D., & Gronthos, S. (2019). Epigenetic Regulation of Bone Marrow Stem Cell Aging: Revealing Epigenetic Signatures associated with Hematopoietic and Mesenchymal Stem Cell Aging. AGING AND DISEASE, 10(1), 174-189.
DOI Scopus63 WoS53 Europe PMC57
2019 Yang, D., Gronthos, S., Isenmann, S., Morris, H. A., & Atkins, G. J. (2019). The late osteoblast/preosteocyte cell line MLO-A5 displays mesenchymal lineage plasticity in vitro and in vivo. Stem Cells International, 2019, 9838167-1-9838167-10.
DOI Scopus4 WoS3 Europe PMC2
2019 Gancheva, M. R., Kremer, K. L., Gronthos, S., & Koblar, S. A. (2019). Using dental pulp stem cells for stroke therapy. Frontiers in Neurology, 10(APR), 422-1-422-17.
DOI Scopus28 WoS27 Europe PMC25
2019 Arthur, A., Nguyen, T. M., Paton, S., Zannettino, A. C. W., & Gronthos, S. (2019). Loss of EfnB1 in the osteogenic lineage compromises their capacity to support hematopoietic stem/progenitor cell maintenance. Experimental Hematology, 69, 43-53.
DOI Scopus14 WoS14 Europe PMC13
2018 Rasi Ghaemi, S., Delalat, B., Gronthos, S., Alexander, M. R., Winkler, D. A., Hook, A. L., & Voelcker, N. H. (2018). High-throughput assessment and modeling of a polymer library regulating human dental pulp-derived stem cell behavior. ACS Applied Materials and Interfaces, 10(45), 38739-38748.
DOI Scopus18 WoS18 Europe PMC10
2018 Arthur, A., Nguyen, T., Paton, S., Klisuric, A., Zannettino, A., & Gronthos, S. (2018). The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption. Scientific Reports, 8(1), 12756-1-12756-12.
DOI Scopus16 WoS15 Europe PMC12
2018 Su, Y. W., Chim, S. M., Zhou, L., Hassanshahi, M., Chung, R., Fan, C., . . . Xian, C. J. (2018). Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats. Bone, 116, 232-247.
DOI Scopus18 WoS16 Europe PMC13
2018 Camp-Dotlic, E., Pribadi, C., Anderson, P., Zannettino, A., & Gronthos, S. (2018). miRNA-376c-3p mediates TWIST-1 inhibition of BMSC osteogenesis and can reduce aberrant bone formation of TWIST-1 haploinsufficient calvarial cells. Stem Cells and Development, 27(23), 1621-1633.
DOI Scopus16 WoS16 Europe PMC13
2018 Martin, S., Fitter, S., El Khawanky, N., Grose, R., Walkley, C., Purton, L., . . . Zannettino, A. (2018). mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis. Scientific Reports, 8(1), 14501-1-14501-10.
DOI Scopus17 WoS16 Europe PMC16
2018 Hynes, K., Bright, R., Marino, V., Ng, J., Verma, P., Gronthos, S., & Bartold, P. (2018). Potential of iPSC-derived mesenchymal stromal cells for treating periodontal disease. Stem Cells International, 2018, 2601945-1-2601945-12.
DOI Scopus26 WoS21 Europe PMC18
2018 Camp, E., Anderson, P., Zannettino, A., Glackin, C., & Gronthos, S. (2018). Tyrosine kinase receptor c-ros-oncogene 1 inhibition alleviates aberrant bone formation of TWIST-1 haploinsufficient calvarial cells from Saethre-Chotzen syndrome patients. Journal of Cellular Physiology, 233(9), 7320-7332.
DOI Scopus9 WoS7 Europe PMC8
2017 Wu, J., Shimmon, S., Paton, S., Daly, C., Goldschlager, T., Gronthos, S., . . . Ghosh, P. (2017). Pentosan polysulfate binds to STRO-1+mesenchymal progenitor cells, is internalized, and modifies gene expression: A novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis. Stem Cell Research and Therapy, 8(1), 15 pages.
DOI Scopus9 WoS9 Europe PMC8
2017 Bachhuka, A., Delalat, B., Ghaemi, S., Gronthos, S., Voelcker, N., & Vasilev, K. (2017). Nanotopography mediated osteogenic differentiation of human dental pulp derived stem cells. Nanoscale, 9(37), 14248-14258.
DOI Scopus34 WoS34 Europe PMC24
2017 Fitter, S., Matthews, M., Martin, S., Xie, J., Ooi, S., Walkley, C., . . . Zannettino, A. (2017). mTORC1 plays an important role in skeletal development by controlling preosteoblast differentiation. Molecular and Cellular Biology, 37(7), e00668-1-e00668-20.
DOI Scopus57 WoS53 Europe PMC51
2017 Fitter, S., Gronthos, S., Ooi, S. S., & Zannettino, A. C. W. (2017). The mesenchymal precursor cell marker antibody STRO-1 binds to cell surface heat shock cognate 70. Stem Cells, 35(4), 940-951.
DOI Scopus35 WoS30 Europe PMC31
2017 Sivanathan, K., Gronthos, S., Grey, S., Rojas-Canales, D., & Coates, P. (2017). Immunodepletion and hypoxia preconditioning of mouse vompact bone cells as a novel protocol to isolate highly immunosuppressive mesenchymal stem cells. Stem Cells and Development, 26(7), 512-527.
DOI Scopus17 WoS16 Europe PMC13
2017 Hemming, S., Cakouros, D., Codrington, J., Vandyke, K., Arthur, A., Zannettino, A., & Gronthos, S. (2017). EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture & structural integrity and accelerates remodeling. FASEB Journal, 31(3), 1011-1027.
DOI Scopus54 WoS56 Europe PMC52
2017 Nguyen, T., Arthur, A., Zannettino, A., & Gronthos, S. (2017). EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac1 activation. Experimental Hematology, 48, 72-78.
DOI Scopus23 WoS21 Europe PMC20
2017 Bartold, P. M., & Gronthos, S. (2017). Standardization of Criteria Defining Periodontal Ligament Stem Cells. Journal of Dental Research, 96(5), 487-490.
DOI Scopus40 WoS35 Europe PMC29
2017 Vandyke, K., Zeissig, M., Hewett, D., Martin, S., Mrozik, K., Cheong, C., . . . Zannettino, A. (2017). HIF-2α promotes dissemination of plasma cells in multiple myeloma by regulating CXCL12/CXCR4 and CCR1. Cancer Research, 77(20), 5452-5463.
DOI Scopus50 WoS47 Europe PMC42
2017 Camp, E., Anderson, P. J., Zannettino, A. C. W., & Gronthos, S. (2017). Tyrosine kinase receptor c-ros-oncogene 1 mediates TWIST-1 regulation of human mesenchymal stem cell lineage commitment. Bone, 94, 98-107.
DOI Scopus17 WoS17 Europe PMC15
2017 Sivanathan, K. N., Rojas-Canales, D., Grey, S. T., Gronthos, S., & Coates, P. T. (2017). Transcriptome profiling of IL-17A preactivated mesenchymal stem cells: a comparative study to unmodified and IFN-γ modified mesenchymal stem cells. Stem Cells International, 2017, 1025820-1-1025820-16.
DOI Scopus37 WoS35 Europe PMC32
2017 Tomokiyo, A., Hynes, K., Ng, J., Menicanin, D., Camp, E., Arthur, A., . . . Bartold, P. M. (2017). Generation of neural crest-like cells from human periodontal ligament cell-derived induced pluripotent stem cells. Journal of Cellular Physiology, 232(2), 402-416.
DOI Scopus20 WoS18 Europe PMC14
2016 Nguyen, T., Arthur, A., & Gronthos, S. (2016). The role of Eph/ephrin molecules in stromal–hematopoietic interactions. International Journal of Hematology, 103(2), 145-154.
DOI Scopus21 WoS21 Europe PMC15
2016 Harding, F., Surdo, S., Delalat, B., Cozzi, C., Elnathan, R., Gronthos, S., . . . Barillaro, G. (2016). Ordered silicon pillar arrays prepared by electrochemical micromachining: substrates for high-efficiency cell transfection. ACS Applied Materials and Interfaces, 8(43), 29197-29202.
DOI Scopus49 WoS47 Europe PMC27
2016 Ebert, L. M., Tan, L. Y., Johan, M. Z., Min, K. K. M., Cockshell, M. P., Parham, K. A., . . . Bonder, C. S. (2016). A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis. Angiogenesis, 19(4), 463-486.
DOI Scopus38 WoS38 Europe PMC30
2016 Xiong, J., Menicanin, D., Zilm, P., Marino, V., Bartold, P., & Gronthos, S. (2016). Investigation of the cell surface proteome of human periodontal ligament stem cells. Stem Cells International, 2016(1), 1947157-1-1947157-13.
DOI Scopus19 WoS10 Europe PMC15
2016 Nguyen, T., Arthur, A., Paton, S., Hemming, S., Panagopoulos, R., Codrington, J., . . . Gronthos, S. (2016). Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development. Bone, 93, 12-21.
DOI Scopus20 WoS20 Europe PMC15
2016 Hynes, K., Bright, R., Proudman, S., Haynes, D., Gronthos, S., & Bartold, M. (2016). Immunomodulatory properties of mesenchymal stem cell in experimental arthritis in rat and mouse models: a systematic review. Seminars in Arthritis and Rheumatism, 46(1), 1-19.
DOI Scopus22 WoS19 Europe PMC17
2016 Hemming, S., Cakouros, D., Vandyke, K., Davis, M. J., Zannettino, A. C. W., & Gronthos, S. (2016). Identification of novel EZH2 targets regulating osteogenic differentiation in mesenchymal stem cells. Stem Cells and Development, 25(12), 909-921.
DOI Scopus69 WoS67 Europe PMC58
2016 Ng, J., Hynes, K., White, G., Sivanathan, K., Vandyke, K., Bartold, P., & Gronthos, S. (2016). Immunomodulatory properties of induced pluripotent stem cell-derived mesenchymal cells. Journal of Cellular Biochemistry, 117(12), 2844-2853.
DOI Scopus41 WoS41 Europe PMC36
2016 Qin, S., Kusuma, G., Al-Sowayan, B., Pace, R., Isenmann, S., Pertile, M., . . . Kalionis, B. (2016). Establishment and characterization of fetal and maternal mesenchymal stem/stromal cell lines from the human term placenta. Placenta, 39, 134-146.
DOI Scopus43 WoS34 Europe PMC34
2016 Freeman, B., Kuliwaba, J., Jones, C., Shu, C., Colloca, C., Zarrinkalam, M., . . . Howell, S. (2016). Allogeneic mesenchymal precursor cells promote healing in postero-lateral annular lesions and improve indices of lumbar intervertebral disc degeneration in an ovine model. Spine, 41(17), 1331-1339.
DOI Scopus48 WoS40 Europe PMC31
2016 Arthur, A., Cakouros, D., Cooper, L., Nguyen, T., Isenmann, S., Zannettino, A., . . . Gronthos, S. (2016). Twist-1 enhances bone marrow mesenchymal stromal cell support of hematopoiesis by modulating CXCL12 expression. Stem Cells, 34(2), 504-509.
DOI Scopus21 WoS21 Europe PMC20
2016 M Nguyen, T., Arthur, A., & Gronthos, S. (2016). Eph/ephrin-mediated mesenchymal stem cell regulation of T-cell activation and function. Journal of Clinical and Cellular Immunology, 7(3), 418-1-418-7.
DOI
2016 Hynes, K., Menicanin, D., Gronthos, S., & Bartold, M. P. (2016). Differentiation of iPSC to mesenchymal stem-like cells and their characterization. Methods in molecular biology (Clifton, N.J.), 1357, 353-374.
DOI Scopus23 Europe PMC21
2016 Bartold, P., Gronthos, S., Ivanovski, S., Fisher, A., & Hutmacher, D. (2016). Tissue engineered periodontal products. Journal of Periodontal Research, 51(1), 1-15.
DOI Scopus106 WoS88 Europe PMC71
2015 Martin, S., Fitter, S., Dutta, A., Matthews, M., Walkley, C., Hall, M., . . . Zannettino, A. (2015). Brief report: The differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation. Stem Cells, 33(4), 1359-1365.
DOI Scopus80 WoS76 Europe PMC73
2015 Cakouros, D., Isenmann, S., Hemming, S., Menicanin, D., Camp, E., Zannetinno, A., & Gronthos, S. (2015). Novel basic helix-loop-helix transcription factor hes4 antagonizes the function of twist-1 to regulate lineage commitment of bone marrow stromal/stem cells. Stem Cells and Development, 24(11), 1297-1308.
DOI Scopus27 WoS28 Europe PMC27
2015 Bright, R., Hynes, K., Gronthos, S., & Bartold, P. (2015). Periodontal ligament-derived cells for periodontal regeneration in animal models: a systematic review. Journal of Periodontal Research, 50(2), 160-172.
DOI Scopus121 WoS109 Europe PMC98
2015 Wada, N., Tomokiyo, A., Gronthos, S., & Bartold, P. M. (2015). Immunomodulatory Properties of PDLSC and Relevance to Periodontal Regeneration. Current Oral Health Reports, 2(4), 245-251.
DOI Scopus17
2015 Tomokiyo, A., Hynes, K., Gronthos, S., Wada, N., & Bartold, P. M. (2015). Is There a Role for Neural Crest Stem Cells in Periodontal Regeneration?. Current Oral Health Reports, 2(4), 275-281.
DOI Scopus5
2015 Kusuma, G., Menicanin, D., Gronthos, S., Manuelpillai, U., Abumaree, M., Pertile, M., . . . Kalionis, B. (2015). Ectopic bone formation by mesenchymal stem cells derived from human term placenta and the decidua. PLoS One, 10(10), e0141246-1-e0141246-13.
DOI Scopus42 WoS40 Europe PMC33
2015 Hynes, K., Menichanin, D., Bright, R., Ivanovski, S., Hutmacher, D., Gronthos, S., & Bartold, P. (2015). Induced pluripotent stem cells. Journal of Dental Research, 94(11), 1508-1515.
DOI Scopus34 WoS26 Europe PMC21
2015 Jackson, M., Derrick Roberts, A., Martin, E., Rout-Pitt, N., Gronthos, S., & Byers, S. (2015). Mucopolysaccharidosis enzyme production by bone marrow and dental pulp derived human mesenchymal stem cells. Molecular Genetics and Metabolism, 114(4), 584-593.
DOI Scopus10 WoS11 Europe PMC11
2015 Sivanathan, K., Rojas-Canales, D., Hope, C., Krishnan, R., Carroll, R., Gronthos, S., . . . Coates, P. (2015). Interleukin-17A induced human mesenchymal stem cells are superior modulators of immunological function. Stem Cells, 33(9), 2850-2863.
DOI Scopus111 WoS110 Europe PMC100
2015 Nguyen, T., Arthur, A., Panagopoulos, R., Paton, S., Hayball, J., Zannettino, A., . . . Gronthos, S. (2015). EphB4 expressing stromal cells exhibit an enhanced capacity for hematopoietic stem cell maintenance. Stem Cells, 33(9), 2838-2849.
DOI Scopus30 WoS30 Europe PMC26
2014 Hynes, K., Menicanin, D., Mrozik, K., Gronthos, S., & Bartold, P. (2014). Generation of functional mesenchymal stem cells from different induced pluripotent stem cell lines. Stem Cells and Development, 23(10), 1084-1096.
DOI Scopus149 WoS136 Europe PMC122
2014 Menicanin, D., Mrozik, K., Wada, N., Marino, V., Shi, S., Bartold, P., & Gronthos, S. (2014). Periodontal-ligament-derived stem cells exhibit the capacity for long-term survival, self-renewal, and regeneration of multiple tissue types in vivo. Stem Cells and Development, 23(9), 1001-1011.
DOI Scopus125 WoS114 Europe PMC95
2014 Han, J., Menicanin, D., Gronthos, S., & Bartold, P. (2014). Stem cells, tissue engineering and periodontal regeneration. Australian Dental Journal, 59(Suppl. 1), 117-130.
DOI Scopus176 WoS146 Europe PMC132
2014 Han, J., Menicanin, D., Marino, V., Ge, S., Mrozik, K., Gronthos, S., & Bartold, P. (2014). Assessment of the regenerative potential of allogeneic periodontal ligament stem cells in a rodent periodontal defect model. Journal of Periodontal Research, 49(3), 333-345.
DOI Scopus84 WoS70 Europe PMC66
2014 Wada, N., Maeda, H., Hasegawa, D., Gronthos, S., Bartold, P., Menicanin, D., . . . Akamine, A. (2014). Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells. Stem Cells and Development, 23(18), 2225-2236.
DOI Scopus34 WoS30 Europe PMC28
2014 Richardson, J., Psaltis, P., Frost, L., Paton, S., Carbone, A., Bertaso, A., . . . Worthley, S. (2014). Incremental benefits of repeated mesenchymal stromal cell administration compared with solitary intervention after myocardial infarction. Cytotherapy, 16(4), 460-470.
DOI Scopus22 WoS22 Europe PMC19
2014 Hynes, K., Gronthos, S., & Bartold, P. M. (2014). iPSC for Dental Tissue Regeneration. Current Oral Health Reports, 1(1), 9-15.
DOI Scopus10
2014 Hemming, S., Cakouros, D., & Gronthos, S. (2014). Detachment of mesenchymal stem cells with trypsin/EDTA has no effect on apoptosis detection. Stem Cells, 32(7), 1991-1992.
DOI Scopus1
2014 Noll, J., Williams, S., Tong, C., Wang, H., Quach, J., Purton, L., . . . Zannettino, A. (2014). Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells. Haematologica, 99(1), 163-171.
DOI Scopus104 WoS91 Europe PMC86
2014 Sivanathan, K., Gronthos, S., Rojas-Canales, D., Thierry, B., & Coates, P. (2014). Interferon-gamma modification of mesenchymal stem cells: implications of autologous and allogeneic mesenchymal stem cell therapy in allotransplantation. Stem Cell Reviews and Reports, 10(3), 351-375.
DOI Scopus134 WoS128 Europe PMC113
2014 Ivanovski, S., Vaquette, C., Gronthos, S., Hutmacher, D., & Bartold, P. (2014). Multiphasic scaffolds for periodontal tissue engineering. Journal of Dental Research, 93(12), 1212-1221.
DOI Scopus193 WoS159 Europe PMC140
2014 Haridas, V., Sadanandan, S., Collart-Dutilleul, P., Gronthos, S., & Voelcker, N. (2014). Lysine-appended polydiacetylene scaffolds for human mesenchymal stem cells. Biomacromolecules, 15(2), 582-590.
DOI Scopus26 WoS24 Europe PMC11
2014 Roohani-Esfahani, S., Wong, K., Lu, Z., Chen, Y., Li, J., Gronthos, S., . . . Zreiqat, H. (2014). Fabrication of a novel triphasic and bioactive ceramic and evaluation of its in vitro and in vivo cytocompatibility and osteogenesis. Journal of Materials Chemistry B, 2(13), 1866-1878.
DOI Scopus18 WoS18 Europe PMC9
2014 Hemming, S., Cakouros, D., Isenmann, S., Cooper, L., Menicanin, D., Zannettino, A., & Gronthos, S. (2014). EZH2 and KDM6A act as an epigenetic switch to regulate mesenchymal stem cell lineage specification. Stem cells, 32(3), 802-815.
DOI Scopus232 WoS218 Europe PMC197
2014 Frith, J., Menzies, D., Cameron, A., Ghosh, P., Whitehead, D., Gronthos, S., . . . Cooper-White, J. (2014). Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration. Biomaterials, 35(4), 1150-1162.
DOI Scopus63 WoS59 Europe PMC46
2013 Mrozik, K., Wada, N., Marino, V., Richter, W., Shi, S., Wheeler, D., . . . Bartold, P. (2013). Regeneration of periodontal tissues using allogeneic periodontal ligament stem cells in an ovine model. Regenerative Medicine, 8(6), 711-723.
DOI Scopus68 WoS57 Europe PMC47
2013 Richardson, J., Bertaso, A., Frost, L., Psaltis, P., Carbone, A., Koschade, B., . . . Worthley, S. (2013). Cardiac magnetic resonance, transthoracic and transoesophageal echocardiography: a comparison of invivo assessment of ventricular function in rats. Laboratory Animals, 47(4), 291-300.
DOI Scopus7 WoS6 Europe PMC5
2013 Nguyen, T., Arthur, A., Hayball, J., & Gronthos, S. (2013). Ephb and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells. Stem Cells and Development, 22(20), 2751-2764.
DOI Scopus64 WoS63 Europe PMC56
2013 Frith, J., Cameron, A., Menzies, D., Ghosh, P., Whitehead, D., Gronthos, S., . . . Cooper-White, J. (2013). An injectable hydrogel incorporating mesenchymal precursor cells and pentosan polysulphate for intervertebral disc regeneration. Biomaterials, 34(37), 9430-9440.
DOI Scopus147 WoS131 Europe PMC108
2013 Hynes, K., Menicanin, D., Han, J., Marino, V., Mrozik, K., Gronthos, S., & Bartold, P. (2013). Mesenchymal stem cells from iPS cells facilitate periodontal regeneration. Journal of Dental Research, 92(9), 833-839.
DOI Scopus138 WoS121 Europe PMC109
2013 Ghaemi, S., Harding, F., Delalat, B., Gronthos, S., & Voelcker, N. (2013). Exploring the mesenchymal stem cell niche using high throughput screening. Biomaterials, 34(31), 7601-7615.
DOI Scopus52 WoS46 Europe PMC32
2013 Richardson, J., Bertaso, A., Psaltis, P., Frost, L., Carbone, A., Paton, S., . . . Worthley, S. (2013). Impact of timing and dose of mesenchymal stromal cell therapy in a preclinical model of acute myocardial infarction. Journal of Cardiac Failure, 19(5), 342-353.
DOI Scopus47 WoS43 Europe PMC36
2013 Richardson, J., Nelson, A., Zannettino, A., Gronthos, S., Worthley, S., & Psaltis, P. (2013). Optimization of the cardiovascular therapeutic properties of mesenchymal stromal/stem cells-taking the next step. Stem Cell Reviews, 9(3), 281-302.
DOI Scopus23 WoS23 Europe PMC23
2013 Arthur, A., Panagopoulos, R., Cooper, L., Menicanin, D., Parkinson, I., Codrington, J., . . . Gronthos, S. (2013). EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repair. Journal of Bone and Mineral Research, 28(4), 926-935.
DOI Scopus42 WoS35 Europe PMC39
2013 Wada, N., Gronthos, S., & Bartold, P. (2013). Immunomodulatory effects of stem cells. Periodontology 2000, 63(1), 198-216.
DOI Scopus100 WoS94 Europe PMC82
2013 Xiong, J., Gronthos, S., & Bartold, P. (2013). Role of the epithelial cell rests of Malassez in the development, maintenance and regeneration of periodontal ligament tissue. Periodontology 2000, 63(1), 217-233.
DOI Scopus96 WoS85 Europe PMC71
2012 Cakouros, D., Isenmann, S., Cooper, L., Zannettino, A., Anderson, P., Glackin, C., & Gronthos, S. (2012). Twist-1 Induces Ezh2 Recruitment Regulating Histone Methylation along the Ink4A/Arf Locus in Mesenchymal Stem Cells. Molecular and Cellular Biology, 32(8), 1433-1441.
DOI Scopus111 WoS106 Europe PMC91
2012 Leong, W., Henshall, T., Arthur, A., Kremer, K., Lewis, M., Helps, S., . . . Koblar, S. (2012). Human adult dental pulp stem cells enhance poststroke functional recovery through non-neural replacement mechanisms. Stem Cells Translational Medicine, 1(3), 177-187.
DOI Scopus153 WoS134 Europe PMC124
2012 Ge, S., Mrozik, K., Menicanin, D., Gronthos, S., & Bartold, P. (2012). Isolation and characterization of mesenchymal stem cell-like cells from healthy and inflamed gingival tissue: Potential use for clinical therapy. Regenerative Medicine, 7(6), 819-832.
DOI Scopus91 WoS77 Europe PMC65
2012 Castrechini, N., Murthi, P., Qin, S., Kusuma, G., Wilton, L., Abumaree, M., . . . Kalionis, B. (2012). Decidua parietalis-derived mesenchymal stromal cells reside in a vascular niche within the choriodecidua. Reproductive Sciences, 19(12), 1302-1314.
DOI Scopus33 WoS27 Europe PMC25
2012 Xiong, J., Mrozik, K., Gronthos, S., & Bartold, P. (2012). Epithelial cell rests of Malassez contain unique stem cell populations capable of undergoing epithelial-mesenchymal transition. Stem Cells and Development, 21(11), 2012-2025.
DOI Scopus60 WoS55 Europe PMC45
2012 Fitter, S., Vandyke, K., Gronthos, S., & Zannettino, A. (2012). Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretion. Journal of Molecular Endocrinology, 48(3), 229-240.
DOI Scopus57 WoS52 Europe PMC54
2012 Mrozik, K., Gronthos, S., Menicanin, D., Marino, V., & Bartold, P. (2012). Effect of coating Straumann® Bone Ceramic with Emdogain on mesenchymal stromal cell hard tissue formation. Clinical Oral Investigations, 16(3), 867-878.
DOI Scopus29 WoS31 Europe PMC26
2012 Ghosh, P., Moore, R., Vernon-Roberts, B., Goldschlager, T., Pascoe, D., Zannettino, A., . . . Itescu, S. (2012). Immunoselected STRO-3⁺ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs: Laboratory investigation. Journal of Neurosurgery: Spine, 16(5), 479-488.
DOI Scopus83 WoS72 Europe PMC58
2012 Hynes, K., Menicanin, D., Gronthos, S., & Bartold, P. (2012). Clinical utility of stem cells for periodontal regeneration. Periodontology 2000, 59(1), 203-227.
DOI Scopus204 WoS189 Europe PMC166
2012 Akiyama, K., You, Y., Yamaza, T., Chen, C., Tang, L., Jin, Y., . . . Shi, S. (2012). Characterization of bone marrow derived mesenchymal stem cells in suspension. Stem Cell Research and Therapy, 3(5), 40-1-40-13.
DOI Scopus81 WoS69 Europe PMC63
2011 Gronthos, S. (2011). The therapeutic potential of dental pulp cells: more than pulp fiction?. Cytotherapy, 13(10), 1162-1163.
DOI Scopus15 WoS14 Europe PMC11
2011 Andersen, D., Kortesidis, A., Zannettino, A., Kratchmarova, I., Chen, L., Jensen, O., . . . Kassem, M. (2011). Development of novel monoclonal antibodies that define differentiation stages of human stromal (mesenchymal) stem cells. Molecules and Cells, 32(2), 133-142.
DOI Scopus12 WoS10 Europe PMC10
2011 Martin, S., Diamond, P., Gronthos, S., Peet, D., & Zannettino, A. (2011). The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma. Leukemia, 25(10), 1533-1542.
DOI Scopus110 WoS101 Europe PMC95
2011 Kemoun, P., Gronthos, S., Snead, M., Rue, J., Courtois, B., Vaysse, F., . . . Brunel, G. (2011). The role of cell surface markers and enamel matrix derivatives on human periodontal ligament mesenchymal progenitor responses in vitro. Biomaterials, 32(30), 7375-7388.
DOI Scopus34 WoS28 Europe PMC24
2011 Gronthos, S., Arthur, A., Bartold, P., & Shi, S. (2011). A method to isolate and culture expand human dental pulp stem cells. Methods in Molecular Biology, 698, 107-121.
DOI Scopus100 Europe PMC81
2011 Wada, N., Wang, B., Lin, N., Laslett, A., Gronthos, S., & Bartold, P. (2011). Induced pluripotent stem cell lines derived from human gingival fibroblasts and periodontal ligament fibroblasts. Journal of Periodontal Research, 46(4), 438-447.
DOI Scopus122 WoS102 Europe PMC84
2011 Field, J., Mc Gee, M., Stanley, R., Ruthenbeck, G., Papadimitrakis, T., Zannettino, A., . . . Itescu, S. (2011). The efficacy of allogeneic mesenchymal precursor cells for the repair of an ovine tibial segmental defect. Veterinary and Comparative Orthopaedics and Traumatology, 24(2), 113-121.
DOI Scopus37 WoS40 Europe PMC29
2011 Wada, N., Bartold, P., & Gronthos, S. (2011). Human foreskin fibroblasts exert immunomodulatory properties by a different mechanism to bone marrow stromal/stem cells. Stem Cells and Development, 20(4), 647-659.
DOI Scopus53 WoS48 Europe PMC41
2011 Arthur, A., Zannettino, A., Panagopoulos, R., Koblar, S., Sims, N., Stylianou, C., . . . Gronthos, S. (2011). EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiation. Bone, 48(3), 533-542.
DOI Scopus78 WoS74 Europe PMC70
2011 See, F., Seki, T., Psaltis, P., Sondermeijer, H., Gronthos, S., Zannettino, A., . . . Itescu, S. (2011). Therapeutic Effects of Human STRO-3-Selected Mesenchymal Precursor Cells and their Soluble Factors in Experimental Myocardial Ischemia. Journal of Cellular and Molecular Medicine, 15(10), 2117-2129.
DOI Scopus51 WoS49 Europe PMC43
2011 Psaltis, P., Carbone, A., Leong, D., Lau, D., Nelson, A., Kuchel, T., . . . Worthley, S. (2011). Assessment of myocardial fibrosis by endoventricular electromechanical mapping in experimental nonischemic cardiomyopathy. International Journal of Cardiovascular Imaging, 27(1), 25-37.
DOI Scopus32 WoS29 Europe PMC28
2011 Field, J. R., McGee, M., Stanley, R., Ruthenbeck, G., Papadimitrakis, T., Zannettino, A., . . . Itescu, S. (2011). The efficacy of allogeneic mesenchymal precursor cells for the repair of an ovine tibial segmental defect. Veterinary and Comparative Orthopaedics and Traumatology, 24(3), 256.
DOI Scopus7 WoS2
2010 Goldschlager, T., Ghosh, P., Zannettino, A., Gronthos, S., Rosenfeld, J., Itescu, S., & Jenkin, G. (2010). Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model. Neurosurgical Focus, 28(6), E4-1-E4-8.
DOI Scopus32 WoS24 Europe PMC20
2010 Ghosh, P., Wu, J., Shimmon, S., Zannettino, A., Gronthos, S., & Itescu, S. (2010). Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells. Arthritis Research & Therapy, 12(1), R28-1-R28-17.
DOI Scopus48 WoS47 Europe PMC41
2010 Martin, S., Diamond, P., Williams, S., To, L., Peet, D., Fujii, N., . . . Zannettino, A. (2010). Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells. Haematologica, 95(5), 776-784.
DOI Scopus86 WoS78 Europe PMC67
2010 Zannettino, A., Paton, S., Itescu, S., & Gronthos, S. (2010). Comparative assessment of the osteoconductive properties of different biomaterials in vivo seeded with human or ovine mesenchymal stem/stromal cells. Tissue Engineering. Part A. Tissue Engineering, 16(12), 3579-3587.
DOI Scopus32 WoS29 Europe PMC26
2010 McCarty, R., Xian, C., Gronthos, S., Zannettino, A., & Foster, B. (2010). Application of autologous bone marrow derived mesenchymal stem cells to an ovine model of growth plate cartilage injury. The Open Orthopaedics Journal, 4(1), 220-226.
DOI Scopus39 Europe PMC45
2010 Martin, S., Fitter, S., Bong, L., Drew, J., Gronthos, S., Shepherd, P., & Zannettino, A. (2010). NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells. Journal of Bone and Mineral Research, 25(10), 2126-2137.
DOI Scopus53 WoS51 Europe PMC48
2010 Psaltis, P., Carbone, A., Nelson, A., Lau, D., Jantzen, T., Manavis, J., . . . Worthley, S. (2010). Reparative effects of allogeneic mesenchymal precursor cells delivered transendocardially in experimental nonischemic cardiomyopathy. JACC: Cardiovascular Interventions, 3(9), 974-983.
DOI Scopus64 WoS56 Europe PMC49
2010 Menicanin, D., Bartold, P., Zannettino, A., & Gronthos, S. (2010). Identification of a common gene expression signature associated with immature clonal mesenchymal cell populations derived from bone marrow and dental tissues. Stem Cells and Development, 19(10), 1501-1510.
DOI Scopus77 WoS61 Europe PMC54
2010 Mrozik, K., Zilm, P., Bagley, C., Hack, S., Hoffmann, P., Gronthos, S., & Bartold, P. (2010). Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: Analysis of differentially expressed proteins. Stem Cells and Development, 19(10), 1485-1499.
DOI Scopus64 WoS54 Europe PMC46
2010 Cakouros, D., Raices, R., Gronthos, S., & Glackin, C. (2010). Twist-ing cell fate: mechanistic insights into the role of twist in lineage specification/differentiation and tumorigenesis. Journal of Cellular Biochemistry, 110(6), 1288-1298.
DOI Scopus36 WoS34 Europe PMC31
2010 Williams, S., Martin, S., Vincent, C., Gronthos, S., Zheng, T., Atkins, G., & Zannettino, A. (2010). Circulating levels of TWEAK correlate with bone erosion in multiple myeloma patients. British Journal of Haematology, 150(3), 373-376.
DOI Scopus6 WoS6 Europe PMC4
2010 Castrechini, N., Murthi, P., Gude, N., Erwich, J., Gronthos, S., Zannettino, A., . . . Kalionis, B. (2010). Mesenchymal stem cells in human placental chorionic villi reside in a vascular Niche. Placenta, 31(3), 203-212.
DOI Scopus143 WoS127 Europe PMC104
2010 Psaltis, P., Zannettino, A., Gronthos, S., & Worthley, S. (2010). Intramyocardial navigation and mapping for stem cell delivery. Journal of Cardiovascular Translational Research, 3(2 Sp Iss), 135-146.
DOI Scopus30 WoS24 Europe PMC19
2010 Psaltis, P., Paton, S., See, F., Arthur, A., Martin, S., Itescu, S., . . . Zannettino, A. (2010). Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell populations. Journal of Cellular Physiology, 223(2), 530-540.
DOI Scopus134 WoS123 Europe PMC111
2010 Reichert, J., Woodruff, M., Friis, T., Quent, V., Gronthos, S., Duda, G., . . . Hutmacher, D. (2010). Ovine bone- and marrow-derived progenitor cells and their potential for scaffold-based bone tissue engineering applications in vitro and in vivo. Regenerative Medicine, 4(7), 565-576.
DOI Scopus37 WoS34 Europe PMC30
2010 Yamaza, T., Kentaro, A., Chen, C., Liu, Y., Shi, Y., Gronthos, S., . . . Shi, S. (2010). Immunomodulatory properties of stem cells from human exfoliated deciduous teeth. Current Stem Cell Research & Therapy, 1(5), 1-10.
DOI Scopus315 WoS288 Europe PMC228
2009 Diamond, P., Labrinidis, A., Martin, S., Farrugia, A., Gronthos, S., To, L., . . . Zannettino, A. (2009). Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone loss. Journal of Bone and Mineral Research, 24(7), 1150-1161.
DOI Scopus62 WoS62 Europe PMC52
2009 Wada, N., Menicanin, D., Shi, S., Bartold, P., & Gronthos, S. (2009). Immunomodulatory Properties of Human Periodontal Ligament Stem Cells. Journal of Cellular Physiology, 219(3), 667-676.
DOI Scopus369 WoS340 Europe PMC295
2009 Menicanin, D., Bartold, P., Zannettino, A., & Gronthos, S. (2009). Genomic Profiling of Mesenchymal Stem Cells. Stem Cell Reviews, 5(1), 36-50.
DOI Scopus71 WoS62 Europe PMC47
2009 Mc Carty, R., Gronthos, S., Zannettino, A., Foster, B., & Xian, C. (2009). Characterisation and Developmental Potential of Ovine Bone Marrow Derived Mesenchymal Stem Cells. Journal of Cellular Physiology, 219(2), 324-333.
DOI Scopus136 WoS119 Europe PMC102
2009 Yamaza, T., Miura, Y., Akiyama, K., Bi, Y., Sonoyama, W., Gronthos, S., . . . Shi, S. (2009). Mesenchymal stem cell-mediated ectopic hematopoiesis alleviates aging-related phenotype in immunocompromised mice. Blood, 113(11), 2595-2604.
DOI Scopus42 WoS42 Europe PMC36
2009 Arthur, A., Zannettino, A., & Gronthos, S. (2009). The Therapeutic Applications of Multipotential Mesenchymal/Stromal Stem Cells in Skeletal Tissue Repair. Journal of Cellular Physiology, 218(2), 237-245.
DOI Scopus296 WoS258 Europe PMC215
2009 Isenmann, S., Arthur, A., Zannettino, A., Turner, J., Shi, S., Glackin, C., & Gronthos, S. (2009). TWIST family of basic helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitment. Stem Cells, 27(10), 2457-2468.
DOI Scopus180 WoS178 Europe PMC160
2009 Gronthos, S., McCarty, R., Mrozik, K., Fitter, S., Paton, S., Menicanin, D., . . . Zannettino, A. (2009). Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: Generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues. Stem Cells and Development, 18(9), 1253-1261.
DOI Scopus74 WoS62 Europe PMC52
2009 Huang, G., Gronthos, S., & Shi, S. (2009). Critical reviews in oral biology & medicine: Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine. Journal of Dental Research, 88(9), 792-806.
DOI Scopus1607 WoS1441 Europe PMC1217
2009 Arthur, A., Shi, S., Zannettino, A., Fujii, N., Gronthos, S., & Koblar, S. (2009). Implanted adult human dental pulp stem cells induce endogenous axon guidance. Stem Cells, 27(9), 2229-2237.
DOI Scopus137 WoS125 Europe PMC109
2009 Arthur, A., Koblar, S., Shi, S., & Gronthos, S. (2009). Eph/ephrinB mediate dental pulp stem cell mobilization and function. Journal of Dental Research, 88(9), 829-834.
DOI Scopus38 WoS36 Europe PMC29
2009 Lin, N., Gronthos, S., & Bartold, P. (2009). Stem cells and future periodontal regeneration. Periodontology 2000, 51(1), 239-251.
DOI Scopus107 WoS98 Europe PMC82
2009 Psaltis, P. J., Carbone, A., Lau, D., Jantzen, T., Williams, K., Sanders, P., . . . Worthley, S. G. (2009). Purkinje fiber injury and electrical remodeling in non-ischemic cardiomyopathy: Implications for sudden cardiac death. EUROPEAN HEART JOURNAL, 30, 558.
2009 Psaltis, P. J., See, F., Paton, S., Martens, T. P., Itescu, S., Worthley, S. G., . . . Zannettino, A. C. W. (2009). STRO-1 immunoselection enhances the biological properties and cardiovascular paracrine effects of bone marrow mesenchymal stromal cells. EUROPEAN HEART JOURNAL, 30, 501.
2008 Zannettino, A., Paton, S., Kortesidis, A., Khor, F., Itescu, S., & Gronthos, S. (2008). Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34-/CD45-/glycophorin-A-bone marrow cells. Haematologica, 92(12), 1707-1708.
DOI Scopus78 WoS66 Europe PMC53
2008 Psaltis, P., Carbone, A., Nelson, A., Lau, D., Manavis, J., Finnie, J., . . . Worthley, S. (2008). An ovine model of toxic, nonischemic cardiomyopathy-assessment by cardiac magnetic resonance imaging. Journal of Cardiac Failure, 14(9), 785-795.
DOI Scopus25 WoS19 Europe PMC14
2008 Psaltis, P., Zannettino, A., Worthley, S., & Gronthos, S. (2008). Concise review: Mesenchymal stromal cells: Potential for cardiovascular repair. Stem Cells, 26(9), 2201-2210.
DOI Scopus311 WoS263 Europe PMC227
2008 Arthur, A., Rychkov, G., Shi, S., Koblar, S., & Gronthos, S. (2008). Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues. Stem Cells, 26(7), 1787-1795.
DOI Scopus531 WoS488 Europe PMC421
2008 Lin, N., Menicanin, D., Mrozik, K., Gronthos, S., & Bartold, P. (2008). Putative stem cells in regenerating human periodontium. Journal of Periodontal Research, 43(5), 514-523.
DOI Scopus54 WoS48 Europe PMC41
2008 Zannettino, A., Psaltis, P., & Gronthos, S. (2008). Home is where the heart is: Via the FROUNT. Cell Stem Cell, 2(6), 513-514.
DOI Scopus2 WoS2 Europe PMC2
2008 Lin, N., Gronthos, S., & Bartold, P. (2008). Stem cells and periodontal regeneration. Australian Dental Journal, 53(2), 108-121.
DOI Scopus102 WoS88 Europe PMC74
2008 Liu, Y., Zheng, Y., Ding, G., Fang, D., Zhang, C., Bartold, P., . . . Wang, S. (2008). Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine. Stem Cells, 26(4), 1065-1073.
DOI Scopus538 WoS478 Europe PMC400
2008 Zannettino, A., Paton, S., Arthur, A., Khor, F., Itescu, S., Gimble, J., & Gronthos, S. (2008). Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo. Journal of Cellular Physiology, 214(2), 413-421.
DOI Scopus496 WoS432 Europe PMC377
2008 Yamaza, T., Miura, I., Bi, Y., Liu, Y., Akiyama, K., Sonoyama, W., . . . Shi, S. (2008). Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents. PLoS One, 3(7), 1-9.
DOI Scopus163 WoS154 Europe PMC132
2008 Psaltis, P. J., Gronthos, S., Worthley, S. G., & Zannettino, A. C. W. (2008). Cellular therapy for cardiovascular disease Part 1 - Preclinical insights. Clinical Medicine Insights : Cardiology, 2, 125-138.
2008 Psaltis, P. J., Gronthos, S., Worthley, S. G., & Zannettino, A. C. W. (2008). Cellular therapy for cardiovascular disease Part 2 - Delivery of cells and clinical experience. Clinical Medicine Insights : Cardiology, 2, 139-151.
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2007 Gronthos, S., & Zannettino, A. (2007). The role of the chemokine CXCL12 in osteoclastogenesis. Trends in Endocrinology and Metabolism, 18(3), 108-113.
DOI Scopus52 WoS42 Europe PMC36
2007 Isenmann, S., Cakouros, D., Zannettino, A., Shi, S., & Gronthos, S. (2007). hTERT Transcription is repressed by Cbfa1 in human mesenchymal stem cell populations. Journal of Bone and Mineral Research, 22(6), 897-906.
DOI Scopus25 WoS23 Europe PMC19
2007 Gronthos, S., Fitter, S., Diamond, P., Simmons, P., Itescu, S., & Zannettino, A. (2007). A novel monoclonal antibody (STRO-3) identifies an isoform of tissue nonspecific alkaline phosphatase expressed by multipotent bone marrow stromal stem cells. Stem Cells and Development, 16(6), 953-963.
DOI Scopus106 WoS98 Europe PMC84
2007 Kuznetsov, S., Mankani, M., Leet, A., Ziran, N., Gronthos, S., & Robey, P. (2007). Circulating connective tissue precursors: Extreme rarity in humans and chondrogenic potential in guinea pigs. Stem Cells, 25(7), 1830-1839.
DOI Scopus65 WoS54 Europe PMC47
2007 Zreiqat, H., Howlett, C., Gronthos, S., Hume, D., & Geczy, C. (2007). S100A8/S100A9 and their association with cartilage and bone. Journal of Molecular Histology, 38(5), 381-391.
DOI Scopus52 WoS55 Europe PMC52
2007 Arthur, A., Shi, S., Sun, T., Bartold, P., Koblar, S., & Gronthos, S. (2007). EphB/ephrin-B interaction mediates adult stem cell attachment spreading and migration: Implications for dental tissue repair. Stem Cells, 25(1), 156-164.
DOI Scopus62 WoS61 Europe PMC45
2006 Bartold, P., Shi, S., & Gronthos, S. (2006). Stem cells and periodontal regeneration. Periodontology 2000, 40(1), 164-172.
DOI Scopus188 WoS163 Europe PMC140
2006 Martin, S., Dewar, A., Farrugia, A., Horvath, N., Gronthos, S., To, L., & Zannettino, A. (2006). Tumor angiogenesis is associated with plasma levels of stromal-derived factor-1α in patients with multiple myeloma. Clinical Cancer Research, 12(23), 6973-6977.
DOI Scopus33 WoS30 Europe PMC25
2006 Gronthos, S., Mrozik, K., Shi, S., & Bartold, P. (2006). Ovine periodontal ligament stem cells: Isolation, characterization, and differentiation potential. Calcified Tissue International, 79(5), 310-317.
DOI Scopus152 WoS137 Europe PMC132
2006 Chen, S., Marino, V., Gronthos, S., & Bartold, P. (2006). Location of putative stem cells in human periodontal ligament. Journal of Periodontal Research, 41(6), 547-553.
DOI Scopus148 WoS138 Europe PMC121
2006 Miura, M., Miura, Y., Sonoyama, W., Yamaza, T., Gronthos, S., & Shi, S. (2006). Bone marrow-derived mesenchymal stem cells for regenerative medicine in craniofacial region. Oral Diseases, 12(6), 514-522.
DOI Scopus71 WoS65 Europe PMC53
2006 Ivanovski, S., Gronthos, S., Shi, S., & Bartold, P. (2006). Stem cells in the periodontal ligament. Oral Diseases, 12(4), 358-363.
DOI Scopus162 WoS155 Europe PMC136
2006 Gronthos, S., & Zannettino, A. (2006). Potential of bone marrow stromal stem cells to repair bone defects and fractures. Journal of Stem Cells, 1(1), 35-45.
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2006 Martens, T., See, F., Shuster, M., Sondermeijer, H., Hefti, M., Zannettino, A., . . . Itescu, S. (2006). Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardium. Nature Clinical Practice Cardiovascular Medicine, 3(Suppl 1), 18-22.
DOI Scopus103 Europe PMC69
2006 Gronthos, S., Akintoye, S., Wang, C., & Shi, S. (2006). Bone marrow stromal stem cells for tissue engineering. Periodontology 2000, 41(1), 188-195.
DOI Scopus61 WoS54 Europe PMC41
2006 Miura, Y., Gao, Z., Miura, M., Seo, B., Sonoyama, W., Chen, W., . . . Shi, S. (2006). Mesenchymal stem cell-organized bone marrow elements: an alternative hematopoietic progenitor resource. Stem Cells, 24(11), 2428-2436.
DOI Scopus65 WoS62 Europe PMC45
2006 Liu, H., Gronthos, S., & Shi, S. (2006). Dental pulp stem cells. Methods in Enzymology, 419(419), 99-113.
DOI Scopus112 WoS107 Europe PMC88
2006 Sonoyama, W., Liu, Y., Fang, D., Yamaza, T., Seo, B., Zhang, C., . . . Wang, S. (2006). Mesenchymal stem cell-mediated functional tooth regeneration in swine. PLoS One, Dec 2006(1), e79 (8 pages).
DOI Scopus1100 WoS960 Europe PMC801
2006 Evans, A., Jackson, D., Wall, D., Prince, H. M., Gronthos, S., Zannettino, A., . . . Itescu, S. (2006). Ex vivo expansion of immuno-selected autologous mesenchymal precursor cells (MPC) for use in the treatment of chronic myocardial ischaemia.. CYTOTHERAPY, 8, 1 page.
2005 Martens, T. P., Schuster, M. D., Cheema, F. H., See, F., Topkara, V. K., Colman, D. L., . . . Itescu, S. (2005). Human mesenchymal progenitor cells induce arteriogenesis and cardiac regeneration following acute ischemia in irradiated nude rats. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 24(2), S98.
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2005 Sonoyama, W., Coppe, C., Gronthos, S., & Shi, S. (2005). Skeletal stem cells in regenerative medicine. Current Topics in Developmental Biology, 67(67), 305-323.
DOI Scopus16 WoS6 Europe PMC5
2005 Shi, S., Bartold, P., Miura, M., Seo, B., Robey, P., & Gronthos, S. (2005). The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthodontics & Craniofacial Research, 8(3), 191-199.
DOI Scopus431 Europe PMC323
2005 Miura, Y., Miura, M., Gronthos, S., Allen, M., Cao, C., Uveges, T., . . . Zhang, L. (2005). Defective osteogenesis of the stromal stem cells predisposes CD18-null mice to osteoporosis. Proceedings of the National Academy of Sciences of the United States of America, 102(39), 14022-14027.
DOI Scopus64 WoS65 Europe PMC53
2005 Kortesidis, A., Zannettino, A., Isenmann, S., Shi, S., Lapidot, T., & Gronthos, S. (2005). Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood, 105(10), 3793-3801.
DOI Scopus342 WoS324 Europe PMC279
2005 Hopwood, B., Gronthos, S., Kuliwaba, J., Robey, P., Findlay, D., & Fazzalari, N. (2005). Identification of differentially expressed genes between osteoarthritic and normal trabecular bone from the intertrochanteric region of the proximal femur using cDNA microarray analysis. Bone, 36(4), 635-644.
DOI Scopus21 WoS19 Europe PMC18
2005 Zannettino, A., Farrugia, A., Kortesidis, A., Manavis, J., To, L., Martin, S., . . . Gronthos, S. (2005). Elevated serum levels of stromal-derived factor-1α are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients. Cancer Research, 65(5), 1700-1709.
DOI Scopus187 WoS171 Europe PMC144
2004 Gronthos, S. (2004). Reconstruction of human mandible by tissue engineering. Lancet, 364(9436), 735-736.
DOI Scopus36 WoS30 Europe PMC19
2004 Miura, M., Chen, X., Allen, M., Bi, Y., Gronthos, S., Seo, B., . . . Shi, S. (2004). A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. Journal of Clinical Investigation, 114(12), 1704-1713.
DOI Scopus245 WoS220 Europe PMC185
2004 Seo, B., Miura, M., Gronthos, S., Bartold, P., Batouli, S., Brahim, J., . . . Shi, S. (2004). Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet, 364(9429), 149-155.
DOI Scopus3035 WoS2743 Europe PMC2332
2004 Pan, B., To, L., Farrugia, A., Findlay, D., Green, J., Gronthos, S., . . . Zannettino, A. (2004). The nitrogen-containing bisphosphonate, zoledronic acid, increases mineralisation of human bone-derived cells in vitro. Bone, 34(1), 112-123.
DOI Scopus105 WoS95 Europe PMC76
2004 Seo, B. M., Miura, M., & Gronthos, S. (2004). Erratum: Investigation of multipotent postnatal stem cells from human periodontal ligament (Lancet (2004) 364 149-155)). Lancet, 364(9447), 1756.
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2004 Seo, B. M., Miura, M., & Gronthos, S. (2004). Investigation of multipotent postnatal stem cells from human periodontal ligament. (vol 364, pg 149, 2004). LANCET, 364(9447), 1756.
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2003 Miura, M., Gronthos, S., Zhao, M., Lu, B., Fisher, L. W., Robey, P. G., & Shi, S. (2003). SHED - Stem cells from human exfoliated deciduous teeth.. JOURNAL OF DENTAL RESEARCH, 82, B305.
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2003 Gronthos, S., Zannettino, A., Hay, S., Shi, S., Graves, S., Kortesidis, A., & Simmons, P. (2003). Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. Journal of Cell Science, 116(9), 1827-1835.
DOI Scopus964 WoS816
2003 Atkins, G., Kostakis, P., Pan, B., Farrugia, A., Gronthos, S., Evdokiou, A., . . . Zannettino, A. (2003). RANKL expression is related to the differentiation state of human osteoblasts. Journal of Bone and Mineral Research, 18(6), 1088-1098.
DOI Scopus221 WoS202 Europe PMC178
2003 Gronthos, S., Zannettino, A. C. W., Hay, S. J., Shi, S., Graves, S. E., Kortesidis, A., & Simmons, P. J. (2003). Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow.. Journal of cell science, 116(Pt 9), 1827-1835.
DOI Europe PMC699
2003 Gronthos, S., Chen, S., Wang, C. Y., Robey, P. G., & Shi, S. (2003). Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcin. Journal of Bone and Mineral Research, 18(4), 716-722.
DOI Scopus127 WoS107 Europe PMC91
2003 Miura, M., Gronthos, S., Zhao, M., Lu, B., Fisher, L., Robey, P., & Shi, S. (2003). SHED: Stem cells from human exfoliated deciduous teeth. Proceedings of the National Academy of Sciences of the United States of America, 100(10), 5807-5812.
DOI Scopus2454 WoS2145 Europe PMC1824
2003 Shi, S., & Gronthos, S. (2003). Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. Journal of Bone and Mineral Research, 18(4), 696-704.
DOI Scopus1262 WoS1127 Europe PMC968
2003 Batouli, S., Miura, M., Brahim, J., Tsutsui, T., Fisher, L., Gronthos, S., . . . Shi, S. (2003). Comparison of stem-cell-mediated osteogenesis and dentinogenesis. Journal of Dental Research, 82(12), 976-981.
DOI Scopus341 WoS294 Europe PMC243
2002 Gronthos, S., Brahim, J., Li, W., Fisher, L. W., Cherman, N., Boyde, A., . . . Shi, S. (2002). Stem Cell Properties of Human Dental Pulp Stem Cells. Journal of Dental Research, 81(8), 531-535.
DOI Scopus1715 WoS1550 Europe PMC1307
2002 Shi, S., Gronthos, S., Chen, S., Reddi, A., Counter, C. M., Robey, P. G., & Wang, C. Y. (2002). Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nature Biotechnology, 20(6), 587-591.
DOI Scopus336 WoS324 Europe PMC282
2001 Gronthos, S., Robey, P. G., Boyde, A., & Shi, S. (2001). Human dental pulp stem cells (DPSCs): Characterization and developmental potential.. JOURNAL OF BONE AND MINERAL RESEARCH, 16, S265.
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2001 Shi, S., Robey, P. G., & Gronthos, S. (2001). Adult human dental pulp stem cells (DPSCs) can differentiate into neural-like cells in vitro.. JOURNAL OF BONE AND MINERAL RESEARCH, 16, S496.
2001 Stewart, K., Gronthos, S., Bord, S., Zannettino, A., Simmons, P., & Beresford, J. N. (2001). Further characterisation and molecular cloning of the antibody H8G. JOURNAL OF BONE AND MINERAL RESEARCH, 16(6), 1183.
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2001 Shi, S., Robey, P. G., & Gronthos, S. (2001). Comparison of human dental pulp and bone marrow stromal stem cells by cDNA microarray analysis. Bone, 29(6), 532-539.
DOI Scopus334 WoS295 Europe PMC247
2001 Kuznetsov, S. A., Mankani, M. H., Gronthos, S., Satomura, K., Bianco, P., & Robey, P. G. (2001). Circulating skeletal stem cells. Journal of Cell Biology, 153(5), 1133-1139.
DOI Scopus639 WoS550 Europe PMC457
2001 Bianco, P., Riminucci, M., Gronthos, S., & Robey, P. G. (2001). Bone marrow stromal stem cells: Nature, biology, and potential applications. Stem Cells, 19(3), 180-192.
DOI Scopus1823 WoS1561 Europe PMC1246
2001 Gronthos, S., Franklin, D. M., Leddy, H. A., Robey, P. G., Storms, R. W., & Gimble, J. M. (2001). Surface protein characterization of human adipose tissue-derived stromal cells. Journal of Cellular Physiology, 189(1), 54-63.
DOI Scopus990 WoS828 Europe PMC704
2001 Ramshaw, H. S., Haylock, D., Swart, B., Gronthos, S., Horsfall, M. J., Niutta, S., & Simmons, P. J. (2001). Monoclonal antibody BB9 raised against bone marrow stromal cells identifies a cell-surface glycoprotein expressed by primitive human hemopoietic progenitors. Experimental Hematology, 29(8), 981-992.
DOI Scopus20 WoS18 Europe PMC16
2001 Gronthos, S., Simmons, P. J., Graves, S. E., & G. Robey, P. (2001). Integrin-mediated interactions between human bone marrow stromal precursor cells and the extracellular matrix. Bone, 28(2), 174-181.
DOI Scopus326 WoS291 Europe PMC247
2000 Gronthos, S., Mankani, M., Brahim, J., Robey, P. G., & Shi, S. (2000). Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America, 97(25), 13625-13630.
DOI Scopus4024 WoS3617 Europe PMC3081
2000 Shi, S., Gronthos, S., Mankani, M., Brahim, J., & Robey, P. G. (2000). Comparison of human dental pulp cells (DPCs) and human bone marrow stromal cells (BMSCs) by <i>in vitro</i> and <i>in vivo</i> differentiation.. JOURNAL OF BONE AND MINERAL RESEARCH, 15, S501.
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2000 Gronthos, S., Shi, S., & Robey, P. G. (2000). Comparison of gene expression profiles between human bone marrow stromal cells and human bone cells by microarray (genefilters) analysis.. JOURNAL OF BONE AND MINERAL RESEARCH, 15, S384.
1999 Zannettino, A. C. W., Graves, S. E., Gronthos, S., Hay, S. J., Smith, P., Harrison, K. L., & Simmons, P. J. (1999). The use of expanded populations of osteogenic precursors to reduce large bone defects.. JOURNAL OF BONE AND MINERAL RESEARCH, 14, S316.
1999 Simmons, P. J., Gronthos, S., Dibbens, L., Short, B., Zannettino, A., & Graves, S. E. (1999). The marrow stromal-haematopoietic interface. JOURNAL OF BONE AND MINERAL RESEARCH, 14(6), 1053.
1999 Gronthos, S., Zannettino, A., Graves, S., Ohta, S., Hay, S., & Simmons, P. (1999). Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells. Journal of Bone and Mineral Research, 14(1), 47-56.
DOI Scopus250 WoS234 Europe PMC203
1998 Filshie, R. J. A., Zannettino, A. C. W., Makrynikola, V., Gronthos, S., Henniker, A. J., Bendall, L. J., . . . Bradstock, K. F. (1998). MUC18, a member of the immunoglobulin superfamily, is expressed on bone marrow fibroblasts and a subset of hematological malignancies. Leukemia, 12(3), 414-421.
DOI Scopus78 WoS71 Europe PMC63
1997 Siminons, P., Gronthos, S., Zannettino, A., & Graves, S. (1997). Cell surface antigens expressed by bone marrow stromal cell precursors. Experimental Hematology, 25(8), 736.
1997 Gronthos, S., Stewart, K., Graves, S., Hay, S., & Simmons, P. (1997). Integrin Expression and Function on Human Osteoblast-like Cells. Journal of Bone and Mineral Research, 12(8), 1189-1197.
DOI Scopus227 WoS210 Europe PMC177
1997 Simmons, P. J., Gronthos, S., Zannettino, A., & Graves, S. (1997). Cell surface antigens expressed by bone marrow stromal cell precursors.. EXPERIMENTAL HEMATOLOGY, 25(8), 27.
1997 Gronthos, S., Graves, S. E., & Simmons, P. J. (1997). Purification of human bone marrow stromal precursor cells (CFU-F).. JOURNAL OF BONE AND MINERAL RESEARCH, 12, S207.
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1996 Stewart, K., Gronthos, S., Simmons, P. J., & Beresford, J. N. (1996). H8G: A monoclonal antibody that subtypes the STRO-1(+) CFU-F population of human bone and marrow. JOURNAL OF BONE AND MINERAL RESEARCH, 11(10), P19.
1996 Gronthos, S., & Simmons, P. (1996). The biology and application of human bone marrow stromal cell precursors. Journal of Hematotherapy, 5(1), 15-23.
DOI Scopus102 Europe PMC69
1995 Simmons, P., Gronthos, S., Ohta, S., & Graves, S. (1995). Human bone marrow stromal cell precursors: Identification and developmental potential. Bone Marrow Transplantation, 15(Supplement 1), S3-S8.
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1995 Gronthos, S., & Simmons, P. J. (1995). The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood, 85(4), 929-940.
DOI Scopus308 WoS278 Europe PMC168
1994 Simmons, P. J., Gronthos, S., Zannettino, A., Ohta, S., & Graves, S. (1994). Isolation, characterization and functional activity of human marrow stromal progenitors in hemopoiesis.. Progress in Clinical and Biological Research, 389, 271-280.
Scopus74 Europe PMC39
1994 Simmons, P. J., Zannettino, A., Gronthos, S., & Leavesley, D. (1994). Potential adhesion mechanisms for localisation of haemopoietic progenitors to bone marrow stroma. Leukemia and Lymphoma, 12(5-6), 353-363.
DOI Scopus98 WoS98 Europe PMC54
1994 Gronthos, S., Graves, S. E., Ohta, S., & Simmons, P. J. (1994). The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors. Blood, 84(12), 4164-4173.
DOI Scopus571 WoS477 Europe PMC330
1992 Gronthos, S., To, L. B., Moore, S., Suttle, J. M., & Juttner, C. A. (1992). The detection of Philadelphia chromosome negative metaphases in long-term bone marrow cultures of the peripheral blood from patients with chronic myeloid leukemia predicts response to interferon-alpha 2a. Leukemia, 6(12), 1246-1249.
Scopus4 WoS4 Europe PMC2
1992 Gronthos, S., To, L. B., Haylock, D. N., & Juttner, C. A. (1992). A differential sensitivity to recombinant human interferon-alpha 2a between normal and chronic myeloid leukaemic peripheral blood granulocyte-macrophage colony-forming units. Leukemia Research, 16(2), 153-158.
DOI Scopus14 WoS16 Europe PMC8

Year Citation
2019 Gronthos, S. (2019). Features of mesenchymal stem cells. In X. -D. Chen (Ed.), A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic (pp. 15-38). London, United Kingdom: Academic Press.
DOI Scopus2
2017 Mrozik, K., Gronthos, S., Shi, S., & Bartold, P. M. (2017). A method to isolate, purify, and characterize human periodontal ligament stem cells. In Methods in Molecular Biology (Vol. 1537, pp. 413-427). Springer New York.
DOI Scopus33 Europe PMC23
2017 Ivanovski, S., Mark Bartold, P., Gronthos, S., & Hutmacher, D. (2017). Periodontal tissue engineering. In R. Waddington, & A. Sloan (Eds.), Tissue Engineering and Regeneration in Dentistry: Current Strategies (pp. 124-144). Chichester, West Sussex; UK: Wiley & Sons.
DOI Scopus2
2017 Hemming, S., & Cakouros, D. (2017). Epigenetic regulation of mesenchymal stem/stromal cell growth and multipotentiality. In K. Atkinson (Ed.), The Biology and Therapeutic Application of Mesenchymal Cells (Vol. 1-2, pp. 41-57). Hoboken, New Jersey: John Wiley and Sons.
DOI
2017 Arthur, A., Shi, S., & Gronthos, S. (2017). Dental Pulp Stem Cells: What’s New?. In M. Tatullo (Ed.), MSCs and Innovative Biomaterials in Dentistry (Vol. Part F4902, pp. 1-20). Springer.
DOI Scopus1
2015 Menicanin, D., Hynes, K., Han, J., Gronthos, S., & Bartold, P. (2015). Cementum and periodontal ligament regeneration. In L. Bertassoni, & P. Coelho (Eds.), Engineering Mineralized and Load Bearing Tissues (Vol. 881, pp. 207-236). Switzerland: Springer.
DOI Scopus36 WoS29 Europe PMC21
2014 Arthur, A., Shi, S., & Gronthos, S. (2014). Dental Pulp Stem Cells. In A. Vishwakarma, P. Sharpe, S. Shi, & M. Ramalingam (Eds.), Stem Cell Biology and Tissue Engineering in Dental Sciences (pp. 279-289). United Kingdom: Elsevier Science Publishing Co Inc.
DOI Scopus5
2013 Arthur, A., Zannettino, A., & Gronthos, S. (2013). The multipotential of Mesenchymal / Stromal Stem Cells in Skeletal Tissue Repair.. In R. Rajendram, V. Preedy, & V. Patel (Eds.), Stem Cells and Bone Tissue (pp. 82-102).
DOI Scopus3
2013 Wang, L., Morsczeck, C., Gronthos, S., & Shi, S. (2013). Regulation and differentiation potential of dental mesenchymal stem cells. In G. Huang, & I. Thesleff (Eds.), Stem cells in craniofacial development and regeneration (pp. 303-314). United Kingdom: John Wiley & Sons.
DOI Scopus3
2013 Shi, S., & Gronthos, S. (2013). Bone marrow mesenchymal stem cells. In G. Huang, & I. Thesleff (Eds.), Stem cells in craniofacial development and regeneration (pp. 223-239). United States: John Wiley & Sons.
DOI Scopus3
2012 Mrozik, K., Xiong, J., Zilm, P., Gronthos, S., & Bartold, P. (2012). Proteomic Characterization of Mesenchymal Stem Cell-Like Populations Derived from Various Tissue Types. In M. Hayat (Ed.), Stem cells and cancer stem cells: Therapeutic applications in disease and injury. Volume 3 (pp. 75-94). New York: Springer.
DOI
2012 Akiyama, K., Chen, C., Gronthos, S., & Shi, S. (2012). Lineage differentiation of mesenchymal stem cells from dental pulp, apical papilla, and periodontal ligament. In C. Kioussi (Ed.), Odontogenesis: methods and protocols (Vol. ., pp. 111-121). Humana Press.
DOI Scopus41 Europe PMC35
2012 Mrozik, K., Xiong, J., Zilm, P., Gronthos, S., & Bartold, P. (2012). Proteomic characterization of mesenchymal stem cell-like populations derived from various tissue types. In M. Hayat (Ed.), Stem cells and cancer stem cells: Therapeutic applications in disease and injury. Volume 4 (pp. 267-284). Springer.
DOI
2012 Akiyama, K., Chen, C., Gronthos, S., & Shi, S. (2012). Lineage Differentiation of Mesenchymal Stem Cells from Dental Pulp, Apical Papilla, and Periodontal Ligament. In Methods in Molecular Biology (pp. 111-121). Humana Press.
DOI
2011 Gronthos, S., & Zannettino, A. (2011). Methods for the purification and characterization of human adipose-derived stem cells.. In J. Gimble, & B. Bunnell (Eds.), Methods in Molecular Biology: Adipose-Derived Stem Cells - Methods and Protocols (Vol. 702, 1 ed., pp. 109-120). USA: Humana Press.
DOI Scopus21 Europe PMC17
2010 Mrozik, K., Gronthos, S., Shi, S., & Bartold, P. (2010). A method to isolate, purify, and characterize human periodontal ligament stem cells. In G. Seymour, M. Cullinan, & N. Heng (Eds.), Oral Biology: Molecular Techniques and Applications (Vol. 666, 1 ed., pp. 269-284). USA: Humana Press.
DOI Scopus48 Europe PMC42
2008 Gronthos, S., & Zannettino, A. (2008). A method to isolate and purify human bone marrow stromal stem cells. In D. Prockop, D. Phinney, & B. Bunnell (Eds.), Mesenchymal Stem Cells: Methods and Protocols (Vol. 449, pp. 45-57). United States: Humana Press.
DOI Scopus56 Europe PMC39
2008 Gronthos, S., & Zannettino, A. (2008). Potential of Bone Marrow Stromal Stem Cells to Repair Bone Defects and Fractures. In P. Koka (Ed.), Progress in Stem Cell Research (pp. 47-62). New York: Nova Science Publishers.
2008 Zannettino, A., Martin, S. K., Gronthos, S., To, L., & Peet, D. (2008). The role of CXCL12 in multiple myeloma. In F. columbus (Ed.), Cancer Research Progress. Nova Science Publishers.
2007 Sonoyama, W., Yamaza, T., Gronthos, S., & Shi, S. (2007). Multipotent Stem Cells in Dental Pulp. In Culture of Human Stem Cells (pp. 187-206). Wiley.
DOI Scopus11
1998 Gronthos, S., Graves, S., & Simmons, P. (1998). Isolation, purification and in vitro manipulation of human bone marrow stromal precursor cells. In Marrow stromal cell culture, 1998 (pp. 26-42). Cambridge University Press.

Year Citation
2021 Kutyna, M., Kok, C. H., Wee, L. Y., Paton, S., Chhetri, R., Thomas, D., . . . Hiwase, D. (2021). BONE MARROW MICROENVIRONMENT IN THERAPY-RELATED MYELOID NEOPLASMS IS DISTINCT FROM OTHER MYELOID NEOPLASMS, PROBABLY DRIVEN BY PRIOR CYTOTOXIC THERAPY. In LEUKEMIA RESEARCH Vol. 108 (pp. S18-S19). PERGAMON-ELSEVIER SCIENCE LTD.
2021 Kutyna, M. M., Kok, C. H., Paton, S., Cakouros, D., Arthur, A., Hughes, T. P., . . . Hiwase, D. (2021). Distinct Senescent Bone Marrow Microenvironment in Therapy-Related Myeloid Neoplasms. In BLOOD Vol. 138 (pp. 4 pages). GA, Atlanta: AMER SOC HEMATOLOGY.
DOI WoS1
2020 Campbell, J. M., Habibalahi, A., Mahbub, S., Paton, S., Gronthos, S., & Goldys, E. (2020). Multispectral characterisation of mesenchymal stem/stromal cells: Age, cell cycle, senescence, and pluripotency. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 11251 (pp. 1-7). online: SPIE.
DOI Scopus3 WoS2
2019 Arthur, A., Paton, S., Gronthos, S., & Zannettino, A. (2019). The Loss of ephrinB1 in Osteoprogenitors Delays Fracture Repair. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 34 (pp. 326). Orlando, FL: WILEY.
2019 Kutyna, M., Paton, S., Gronthos, S., & Hiwase, D. (2019). ABERRANT BONE MARROW MICROENVIRONMENT IN THERAPY RELATED MYELOID NEOPLASM. In EXPERIMENTAL HEMATOLOGY Vol. 76 (pp. E3-E4). ELSEVIER SCIENCE INC.
2018 Camp, E., Anderson, P., Zannettino, A., & Gronthos, S. (2018). Inhibition of tyrosine kinase receptor C-ROS-1 as a novel treatment for patients with TWIST haploinsufficiency induced craniosynostosis. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 33 (pp. 424). Montreal, CANADA: WILEY.
2018 Nguyen, T. M., Arthur, A., & Gronthos, S. (2018). EPHA FORWARD SIGNALLINGS ENHANCE HUMAN HAEMATOPOIETIC PROGENITOR CELL MIGRATION AND ADHESION VIA RAC1 ACTIVATION. In JOURNAL OF GENE MEDICINE Vol. 20 (pp. 1 page). Univ Technol Sydney, Sydney, AUSTRALIA: WILEY.
2017 Zeissig, M. N., Hewett, D. R., Martin, S., Mrozik, K. M., Cheong, C. M., Diamond, P., . . . Zannettino, A. C. W. (2017). HIF-2α Upregulates CCR1 to Promote Dissemination of Plasma Cells in Multiple Myeloma. In BLOOD Vol. 130 (pp. 2 pages). Atlanta, GA: AMER SOC HEMATOLOGY.
2016 Sivanathan, K., Rojas-Canales, D., Gronthos, S., Grey, S., & Coates, P. T. (2016). Supercharging mesenchymal stem cells with Interleukin-17A: An alternative to interferon-gamma enhancement of mesenchymal stem cell immunomodulation. In TRANSPLANTATION Vol. 100 (pp. S68-S69). LIPPINCOTT WILLIAMS & WILKINS.
2016 Sivanathan, K., Rojas-Canales, D., Gronthos, S., Grey, S., & Coates, P. T. (2016). Immunodepletion and hypoxia preconditioning of mouse compact bone cells as a novel protocol to isolate highly immunosuppressive mesenchymal stem cells. In TRANSPLANTATION Vol. 100 (pp. S494). LIPPINCOTT WILLIAMS & WILKINS.
2016 Nguyen, T., Arthur, A., Purton, L., Hayball, J., Zannettino, A., Paton, S., . . . Gronthos, S. (2016). EphB4 enhances bone marrow stromal stem cell-mediated support of haematopoiesis. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 173 (pp. 30). British Soc Haematol, Glasgow, SCOTLAND: WILEY-BLACKWELL.
2016 Nguyen, T. M., Arthur, A., Paton, S., Purton, L. E., & Gronthos, S. (2016). EphrinB1 expressing stromal cells exhibit an enhanced capacity for haematopoietic stem cell maintenance. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 173 (pp. 30). British Soc Haematol, Glasgow, SCOTLAND: WILEY-BLACKWELL.
2016 Ebert, L., Tan, L. Y., Min, K. K. M., Cockshell, M., Johan, M. Z., Parham, K., . . . Bonder, C. (2016). Desmoglein 2 (DSG2) is a novel surface marker of endothelial and haematopoietic progenitor cells, and plays a critical role in neoangiogenesis. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 309). Melbourne, AUSTRALIA: WILEY-BLACKWELL.
2015 Sivanathan, K., Rojas-Canales, D., Hope, C., Gronthos, S., Grey, S., & Coates, P. T. (2015). GENE MICROARRAY COMPARATIVE ANALYSIS OF INTERFERON-GAMMA AND INTERLEUKIN-17A PRECONDITIONED HUMAN MESENCHYMAL STEM CELLS.. In TRANSPLANTATION Vol. 99 (pp. S39-S40). Melbourne, AUSTRALIA: LIPPINCOTT WILLIAMS & WILKINS.
2015 Sivanathan, K., Rojas-Canales, D., Gronthos, S., Grey, S., & Coates, P. T. (2015). MICROARRAY GENE PROFILE STUDY OF IMMUNOSUPPRESSIVE INTERLEUKIN-17A PREACTIVATED HUMAN MESENCHYMAL STEM CELLS.. In TRANSPLANTATION Vol. 99 (pp. S48). Lorne, AUSTRALIA: LIPPINCOTT WILLIAMS & WILKINS.
2015 Sivanathan, K., Rojas-Canales, D., Grey, S., Hope, C., Carroll, R., Gronthos, S., & Coates, P. (2015). Interleukin-17A Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 15 (pp. 1 page). Philadelphia, PA: WILEY-BLACKWELL.
2015 Jackson, M. R., Roberts, A. L. K. D., Gronthos, S., & Byers, S. (2015). IDURONIDASE TRANSDUCED MSCS IMPROVE THE BEHAVIOURAL DEFICITS IN MUCOPOLYSACCHARIDOSIS I MICE WITH LIMITED BIOCHEMICAL CORRECTIONS. In JOURNAL OF GENE MEDICINE Vol. 17 (pp. 197-198). Univ Melbourne, Univ Coll, Parkville, AUSTRALIA: WILEY-BLACKWELL.
2015 Sivanathan, K., Canales, D. R., Hope, C., Gronthos, S., Grey, S., & Coates, P. T. (2015). Gene microarray comparative analysis of interferon-gamma and interleukin-17a preconditioned human mesenchymal stem cells. In XENOTRANSPLANTATION Vol. 22 (pp. S25). Melbourne, AUSTRALIA: WILEY-BLACKWELL.
2015 Jackson, M. R., Robertsa, A. L. K. D., Gronthos, S., & Byers, S. (2015). α-l-Iduronidase transduced mesenchymal stem cells improve the behavioral deficits in mucopolysaccharidosis type I mice. In Abstracts Molecular Genetics and Metabolism Vol. 114 (pp. S58). Orlando, FL: Elsevier.
DOI
2013 Noll, J., Williams, S., Tong, C., Wang, H., Purton, L., Farrugia, A., . . . Zannettino, A. (2013). MYELOMA PLASMA CELLS ALTER THE BONE MICROENVIRONMENT BY STIMULATING AN INCREASE IN MESENCHYMAL STEM CELLS: A COMPARATIVE STUDY OF MYELOMA PATIENT- AND MURINE MODEL-DERIVED MESENCHYME. In HAEMATOLOGICA Vol. 98 (pp. 95). FERRATA STORTI FOUNDATION.
2011 Arthur, A., Panagopoulos, R., Cooper, L., Zannettino, A., Koblar, S. A., Sims, N. A., . . . Gronthos, S. (2011). THE ROLE OF EPHB/EPHRINB MOLECULES IN FRACTURE REPAIR. In OSTEOPOROSIS INTERNATIONAL Vol. 22 (pp. S523). Gold Coast, AUSTRALIA: SPRINGER LONDON LTD.
2009 Arthur, A., Stylianou, C., Koblar, S. A., Matsuo, K., & Gronthos, S. (2009). EphB/ephrin-B interactions assist in MSC niche maintenance and contribute to bone remodelling following injury. In BONE Vol. 44 (pp. S142-S143). Sydney, AUSTRALIA: ELSEVIER SCIENCE INC.
DOI
2009 Gronthos, S., Isenmann, S., Arthur, A., Zannettino, A. C. W., Shi, S., & Glackin, C. A. (2009). The role of Twist-1 and-2 in the maintenance of mesenchymal stromal/stem cells. In BONE Vol. 44 (pp. S146). Sydney, AUSTRALIA: ELSEVIER SCIENCE INC.
DOI
2009 Psaltis, P. J., Carbone, A., Manavis, J., Jantzen, T., Lau, D., Sanders, P., . . . Worthley, S. G. (2009). Catheter-based Electromechanical Mapping Accurately Characterizes Segmental Distribution of Left Ventricular Fibrosis in Nonischemic Cardiomyopathy. In CIRCULATION Vol. 120 (pp. S906). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS.
2009 Psaltis, P. J., Zannettino, A., Carbone, A., Manavis, J., Williams, K., Jantzen, T., . . . Worthley, S. G. (2009). Cardiac Repair With Transendocardial Injection of Allogeneic Mesenchymal Precursor Cells for Nonischemic Cardiomyopathy. In CIRCULATION Vol. 120 (pp. S827). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS.
2009 Psaltis, P. J., Worthley, S. G., See, F., Itescu, S., Martens, T., Gronthos, S., & Zannettino, A. (2009). Enrichment for Stro-1 Enhances Paracine-mediated Cardiovascular Repair From Human Bone Marrow Mesenchymal Cells. In CIRCULATION Vol. 120 (pp. S821). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS.
2009 McCarty, R. C., Gronthos, S., Zannettino, A. C., Foster, B. K., & Xian, C. J. (2009). Characterisation of ovine bone marrow derived mesenchymal stromal/stem cells and autologous application to growth plate cartilage defect. In BONE Vol. 45 (pp. S106-S107). Cambridge, ENGLAND: ELSEVIER SCIENCE INC.
DOI
2009 McCarty, R. C., Gronthos, S., Zannettino, A. C., Foster, B. K., & Xian, C. J. (2009). Characterisation of ovine bone marrow derived mesenchymal stem cells and autologous application to growth plate cartilage defect. In BONE Vol. 44 (pp. S159). Sydney, AUSTRALIA: ELSEVIER SCIENCE INC.
DOI
2008 Diamond, P., Labrinidis, A., Martin, S. K., Gronthos, S., To, L., Fuji, N., . . . Zannettino, A. C. W. (2008). Elevated Serum Levels of CXCL12 Is Associated with Increased Osteoclast Activity and Osteolytic Bone Disease in Multiple Myeloma Patients. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 23 (pp. S262). Montreal, CANADA: AMER SOC BONE & MINERAL RES.
2008 Martin, S. K., Diamond, P., To, L. B., Pect, D., Gronthos, S., & Zannettino, A. W. W. (2008). CXCL12 Expression Is Regulated by HIF-2a in Multiple Myeloma Plasma Cells. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 23 (pp. S262). Montreal, CANADA: AMER SOC BONE & MINERAL RES.
2008 Diamond, P., Labrinidis, A., Martin, S. K., Farrugia, A., Gronthos, S., To, L. B., . . . Zannettino, A. (2008). CXCL12 stimulates osteoclastic bone resorption in a novel mouse model of human multiple myeloma. In Journal of Bone and Mineral Research Vol. 23 (pp. S262). Montreal: American Society for Bone and Mineral Research.
2007 Martin, S. K., Dewar, A., Farrugia, A., Horvath, N., Gronthos, S., To, L. B., & Zannettino, A. (2007). Tumour angiogenesis is associated with plasma levels of stromal-derived factor-1a in patients with multiple myeloma. In Haematologica Vol. 92 (pp. 125-126). Kos, Greece: Ferrata Storti Foundation.
2007 See, F., Seki, T., Psaltis, P., Martens, T., Gronthos, S., Worthley, S., . . . Itescu, S. (2007). Human stroll mesenchymal precursor cells induce proliferative effects on vascular smooth muscle cells and endothelium via P13 kinase dependent pathways. In CIRCULATION Vol. 116 (pp. 104). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS.
2007 Arthur, A., Koblar, S., & Gronthos, S. (2007). The role of EphB/ephrin-B interactions in cell attachment and spreading of mesenchymal precursors derived from human bone marrow and dental pulp tissues. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 22 (pp. S370-S371). Honolulu, HI: AMER SOC BONE & MINERAL RES.
2007 Diamond, P., Labrinidis, A., Martin, S. K., Farrugia, A. N., Gronthos, S., To, L. B., . . . Zannettino, A. C. W. (2007). CXCL12 stimulates osteoclastic bone resorption in a novel mouse model of human multiple myeloma. In HAEMATOLOGICA-THE HEMATOLOGY JOURNAL Vol. 92 (pp. 130). Kos Isl, GREECE: FERRATA STORTI FOUNDATION.
2007 Martin, S. K., Dewar, A. L., Farrugia, A. N., Horvath, N., Gronthos, S., To, L. B., & Zannettino, A. C. W. (2007). Tumour angiogenesis correlates with plasma levels of CXCL12 in patients with multiple myeloma. In HAEMATOLOGICA-THE HEMATOLOGY JOURNAL Vol. 92 (pp. 125-126). Kos Isl, GREECE: FERRATA STORTI FOUNDATION.
2005 Miura, Y., Gao, Z. G., Miura, M., Seo, B. M., Sonoyama, W., Chen, W. J., . . . Shi, S. T. (2005). Culture-expanded human bone marrow stromal stem cells organize functional bone marrow niches in vivo.. In BLOOD Vol. 106 (pp. 651A). Atlanta, GA: AMER SOC HEMATOLOGY.
2005 Zannettino, A., Kortesidis, A., Farrugi, A., & Gronthos, S. (2005). The role of stromal derived factor-1 alpha in bone remodelling.. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 20 (pp. S368). Nashville, TN: AMER SOC BONE & MINERAL RES.
2005 McCarty, R. C., Gronthos, S., Foster, B. K., & Xian, C. J. (2005). Development of a mesenchymal stem cell based therapy for repair of growth plate cartilage in an ovine model. In BONE Vol. 36 (pp. S174). Geneva, SWITZERLAND: ELSEVIER SCIENCE INC.
2004 Martens, T. P., Schuster, M. D., See, F., Xydas, S., Hefti, M. M., Gronthos, S., . . . Itescu, S. (2004). Human mesenchymal precursors induce myocardial arteriogenesis and global functional recovery after myocardial ischemia. In CIRCULATION Vol. 110 (pp. 70). New Orleans, LA: LIPPINCOTT WILLIAMS & WILKINS.
2003 Miura, M., Chen, X., Gronthos, S., Bi, Y., Allen, M. R., Lakhani, S., . . . Shi, S. (2003). Caspase-3 deficiency causes osteopenia by attenuating differentiation of osteoblast progenitors.. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 18 (pp. S47). MINNEAPOLIS, MINNESOTA: AMER SOC BONE & MINERAL RES.
2003 Kostakis, P., Atkins, G., Pan, B., Farrugia, A., Gronthos, S., Evdokiou, A., . . . Zannettino, A. (2003). The relationship between RANKL expression and osteoblast differentiation in human osteoblasts. In 30th European Symposium on Calcified Tissues, 8-12 May 2003 Vol. Italy (pp. 314-468). Rome, Italy: Springer Science and Business Media LLC.
DOI
2002 Gronthos, S., Chen, S., Wang, C. Y., Robey, P. G., & Shi, S. (2002). Telomerase accelerates osteogenesis of bone marrow StromalStem cells by increasing proliferation and by up-regulation of CBFA1, osterix, and osteocalcin. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 17 (pp. S196). SAN ANTONIO, TEXAS: AMER SOC BONE & MINERAL RES.
WoS1
2002 Shi, S., Bianco, P., Robey, P. G., & Gronthos, S. (2002). Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp.. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 17 (pp. S446). SAN ANTONIO, TEXAS: AMER SOC BONE & MINERAL RES.
2001 Stewart, K., & Beresford, J. N. (2001). A comparison of STRO-1, HOP-26, CD166 and CD49A as developmental markers for human cells of the osteogenic lineage. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 16 (pp. 1183). AMER SOC BONE & MINERAL RES.
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Year Citation
2022 Doig, R. O., Jenkner, S., Grose, R., Lewis, M., Clark, J., & Gronthos, S. (2022). SPINAL CORD INJURY-DERIVED MONOCYTES ALTER THE VIABILITY AND IMMUNOMODULATORY PHENOTYPE OF NEURAL CREST-DERIVED DENTAL PULP STEM. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Berlin, GERMANY: MARY ANN LIEBERT, INC.
2022 Jenkner, S., Clark, J., Gronthos, S., Grose, R., Lewis, M., & Doig, R. O. (2022). EXPERIMENTAL SPINAL CORD INJURY REVEALS NOVEL HETEROGENIC MONOCYTE SUBPOPULATIONS IN PERIPHERAL BLOOD. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Berlin, GERMANY: MARY ANN LIEBERT, INC.
2019 Kutyna, M. M., Wee, A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2019). Aberrant Bone Marrow Microenvironment in Therapy Related Myeloid Neoplasm (t-MN). Poster session presented at the meeting of BLOOD. FL, Orlando: ELSEVIER.
DOI WoS2
2018 Cakouros, D., Hemming, S., Pribadi, C., Zannettino, A., & Gronthos, S. (2018). EPIGENETIC ENZYMES AND THEIR EMERGING ROLE IN MESENCHYMAL STEM CELL LINEAGE DETERMINATION. Poster session presented at the meeting of JOURNAL OF GENE MEDICINE. Univ Technol Sydney, Sydney, AUSTRALIA: WILEY.
2016 Sivanathan, K., Rojas-Canales, D., Gronthos, S., Grey, S., & Coates, P. (2016). IL-17A Preactivated Mesenchymal Stem Cells (MSC-17) Are Enriched for Genes Involved in T Cell Chemotaxis to Mediate Superior Immunosuppression.. Poster session presented at the meeting of AMERICAN JOURNAL OF TRANSPLANTATION. Boston, MA: WILEY-BLACKWELL.
2015 Kusuma, G., Menicanin, D., Gronthos, S., Abumaree, M., Brennecke, S., & Kalionis, B. (2015). MESENCHYMAL STEM CELTS DERIVED FROM HUMAN TERM, FETAL CHORIONIC VILLI AND THE MATERNAL DECIDUA PRODUCE ECTOPIC BONE <i>IN VIVO</i>. Poster session presented at the meeting of PLACENTA. W B SAUNDERS CO LTD.
DOI
2015 Freeman, B., Kuliwaba, J., Zarrinkalam, M., Jones, C., Shu, C., Colloca, C., . . . Howell, S. (2015). ALLOGENEIC MESENCHYMAL STEM CELLS IMPROVE INDICES OF LUMBAR INTERVERTEBRAL DISC DEGENERATION WITHOUT SITE SPECIFICITY OF INJECTION IN AN OVINE MODEL. Poster session presented at the meeting of OSTEOARTHRITIS AND CARTILAGE. Seattle, WA: ELSEVIER SCI LTD.
DOI WoS1
2015 Koblar, S., Gronthos, S., & Shi, S. (2015). Stem cell therapy in stroke - human dental pulp stem cells from basic science to a clinical trial. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF STROKE. WILEY-BLACKWELL.
2014 Sivanathan, K., Hope, C., Rojas-Canales, D., Carroll, R., Gronthos, S., & Coates, P. (2014). Interferon-gamma and Interleukin-17 Modified Mesenchymal Stem Cells (MSC) Directly or Indirectly Modulate T Cell Responses By Expressing Inhibitory Factors, Downregulating T Cell Activation and Inducing Regulatory T Cells. Poster session presented at the meeting of AMERICAN JOURNAL OF TRANSPLANTATION. San Francisco, CA: WILEY-BLACKWELL.
2014 Sivanathan, K., Hope, C., Rojas-Canales, D., Carroll, R., Gronthos, S., & Coates, P. (2014). Interferon-gamma and Interleukin-17 Modified Mesenchymal Stem Cells (MSC) Directly or Indirectly Modulate T Cell Responses By Expressing Inhibitory Factors, Downregulating T Cell Activation and Inducing Regulatory T Cells.. Poster session presented at the meeting of TRANSPLANTATION. San Francisco, CA: LIPPINCOTT WILLIAMS & WILKINS.
DOI
2013 Thao, N., Gronthos, S., Arthur, A., & Hayball, J. (2013). Ephb and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells. Poster session presented at the meeting of Abstracts of the Ephb and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells, as published in Experimental Hematology. Vienna, AUSTRIA: Elsevier.
DOI
2012 Kusuma, G., Qin, S., Abumaree, M., Isenmann, S., Gronthos, S., Dimitriadis, E., . . . Kalionis, B. (2012). CHARACTERIZATION OF MESENCHYMAL STEM CELL LINES FROM THE HUMAN PLACENTA AND DECIDUA BY MEASUREMENT OF THE NOVEL STEMNESS MARKER, ALDEHYDE DEHYDROGENASE (ALDH). Poster session presented at the meeting of PLACENTA. Hiroshima, JAPAN: W B SAUNDERS CO LTD.
2012 Frith, J. E., Menzies, D. J., Cameron, A. R., Gronthos, S., Zannettino, A. C. W., Ghosh, P., & Cooper-White, J. J. (2012). A novel injectable hydrogel for intervertebral disc regeneration. Poster session presented at the meeting of JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. WILEY-BLACKWELL.

Year Citation
2016 Sivanathan, K. N. (2016). Interleukin-17A induced human mesenchymal stem cells are superior modulators of immunological function. (PhD Thesis, University of Adelaide).

National Health & Medical Research Council, Project Grant # APP1141361 (AUD $850,228.50) 2018-2021. Title: Deregulation of DNA hydroxymethylases Tet1 and Tet2 compromises skeletal integrity during ageing and osteoporosis. Chief Investigators: Stan Gronthos, Tuan Nguyen, Melissa Davis.

National Health & Medical Research Council, Project Grant # APP1142954 (AUD $548,854) 2018-2020. Title: Histone Demethylase KDM6A is a novel target for treating craniosynostosis in children with Saethre-Chotzen Syndrome. Chief Investigators: Stan Gronthos, Peter Anderson.

National Health & Medical Research Council, Project Grant # APP1120989 (AUD$562,863) 2017-2019. Title: Tyrosine kinase receptor c-ros-oncogene 1 mediates Twist-1 haploinsufficiency induced craniosynostosis in children: A novel therapeutic target. Chief investigators: Stan Gronthos, Andrew Zannettino and Peter Anderson.

National Health & Medical Research Council, Principal Research Fellowship # APP1042677 (AUD $714,745) 2013-2017. Title: Mesenchymal stem cells in bone regeneration and repair. Principal Investigator: Stan Gronthos.

National Health & Medical Research Council, Project Grant # APP1099283 (AUD $561,956) 2016-2018. Title: Osteochondroreticular stem cell therapy for osteoarthritis: right cells for the job. Chief Investigators: Dan Worthley, Stan Gronthos, Siddhartha Mukherjee, Francis Lee.

National Health & Medical Research Council, Project Grant # APP1083704 (AUD$548,347) 2015-2017. Title: The role of ephrinB1 reverse signalling in osteogenic differentiation during skeletal development and osteoporosis. Chief investigators: Stan Gronthos, Agnes Arthur and Andrew Zannettino. 

Channel 7 Children’s Research Foundation Grant ($75,000) 2015. Identification of Twist-1 regulated microRNAs which control cranial bone development in Children. Principal Investigators: S. Gronthos, Esther Camp-Dotlic, Peter Anderson.

Australian Dental Research Fund #44-2014 ($11,363) 2015. The role of EphB/ephrinB activation in allogeneic Dental Pulp Stem Cell mediated dental tissue regeneration following tooth injury. Chief investigators: Stan Gronthos, Agnes Arthur.

National Health & Medical Research Council, Project Grant # APP1046053 (AUD$466,044.64) 2013-2015. Title: Twist-1 inhibits MSC osteoblast differentiation during osteoporosis via direct regulation of the Wnt signalling pathway. Chief investigators: Stan Gronthos and Andrew Zannettino.

National Health & Medical Research Council, Project Grant # APP1043994 (AUD$802,470.63) 2013-2015. Title: Comparison of periodontal ligament stem cells and induced pluripotent periodontal ligament stem cells for periodontal regeneration. Chief investigators: Mark Bartold, Stan Gronthos, Saso Ivanovski, Dietmar Hutmacher.

National Health & Medical Research Council, Project Grant #APP1023390 (AUD $591,010) 2012-2014. Title: Mesenchymal Stem Cell maintenance and recruitment during skeletal repair are dependent on EphB-ephrinB signalling. Principal Investigators: S. Gronthos, A.C.W. Zannettino.

National Health & Medical Research Council, Project Grant #APP1030528 (AUD$543,675) 2012-2014. Title: The Role of Raptor and Rictor Signalling Pathways in Osteogenesis and Mesenchymal Stem Cell Fate Determination Investigator(s): Zannettino A, Gronthos S, Fitter S.

Adelaide Research Innovation Commercialization Grant (AUD$100,000) 2014. Title: Characterisation of the molecular target of the monoclonal antibody STRO-1, in mesenchymal stem cell mediated tissue repair and immune modulation. Principal investigators: Zannettino A, Gronthos S, Fitter S.

Australian Cancer Research Foundation Infrastructure Grant ($1.8 million) 2013. South Australian Innovative Cancer Imaging and Therapeutics Facility, SAHMRI. C. Mulligan, T. Hughes, A. Zannettino, D. White, S. Gronthos, D. O’Keefe, G. Goodall, B. To, T. Monro.

Centre for Stem Cell Research, Robinson Institute, University of Adelaide Collaborative Grant ($65,000) 2013. Project:  Understanding the mechanisms of aberrant bone formation in Saethre-Chotzen syndrome patients with Twist-1 mutations. Investigators: S Gronthos and A Zannettino

National Health & Medical Research Council, Senior Research Fellowship #508087(AUD $537,500) 2008-2012. Principal Investigator: Gronthos S.

National Health & Medical Research Council, Project Grant #626910 (AUD $583,500) 2010-2012 Title: Twist-1 Mediated Regulation of Multipotential Mesenchymal Stem Cell Self-Renewal and Cell Fate Determination. Principal Investigators: S. Gronthos, A.C.W. Zannettino

National Health & Medical Research Council, Project Grant #627143 (AUD $769,875) 2010-2012. Project Grant title: Generation of induced pluripotent stem (iPS) cells and their potential use in periodontal regeneration. Principal Investigators: P. M. Bartold, S.Gronthos, P. Zilm, Andrew Laslett.

National Health & Medical Research Council, Project Grant # 626911 (AUD $583,500) 2010-2012. Title: Is Hypoxia Inducible Factor-2 (HIF-2) the "Trigger" of the "Angiogenic Switch" in Multiple Myeloma? Principal Investigators: ACW Zannettino, S Gronthos, J-P Levesque, D Peet, LB To.

 

Date Role Research Topic Program Degree Type Student Load Student Name
2024 Co-Supervisor Capturing Molecular Regulatory Events of Haematopoietic Stem Cell Emergence From Endothelium Doctor of Philosophy Doctorate Full Time Mr Luke Bland
2023 Co-Supervisor The biological function of tryptophan metabolism in triple-negative breast cancer and cancer stem cells population Doctor of Philosophy Doctorate Full Time Mr Jamshid Motalebzadeh
2022 Principal Supervisor Identification of epigenetic factors deregulated in skeletal stem cells during high glucose medicated inhibition of bone formation Doctor of Philosophy Doctorate Part Time Mrs Suzanna Shirazi

Date Role Research Topic Program Degree Type Student Load Student Name
2021 - 2025 Principal Supervisor Bridging the gap: Characterising the peripheral immune response in spinal cord injury to enhance stem cell therapies Doctor of Philosophy Doctorate Full Time Sandra Jenkner
2020 - 2024 Principal Supervisor Deregulation of DNA Hydroxymethylases TET1 and TET2 Compromises Skeletal Integrity During Ageing Doctor of Philosophy Doctorate Full Time Mr Nicholas John Smith
2019 - 2021 Principal Supervisor Role of Eph/ephrin Molecules in Mediating Cross-talk Between Stromal and Neural Populations in the Regulation of Neural Differentiation, Adhesion and Migration Master of Philosophy (Medical Science) Master Full Time Miss Nethmi Abeynayake
2018 - 2022 Principal Supervisor The Role of Epigenetic Modifiers, Kdm6a and Kdm6b, in Calvarial Suture Development and Craniosynostosis Doctor of Philosophy Doctorate Full Time Miss Clara Pribadi
2017 - 2022 Principal Supervisor Evaluating the Role of Bone Marrow Microenvironment in the Pathogenesis of Therapy-related Myeloid Neoplasms Doctor of Philosophy Doctorate Full Time Mrs Monika Maria Kutyna
2016 - 2019 Principal Supervisor Identification of Molecular Mechanisms Mediating TWIST-1 Regulation of Mesenchymal Stem Cell Proliferation and Differentiation Doctor of Philosophy Doctorate Full Time Mr Chee Ho H'ng
2016 - 2021 Co-Supervisor Investigating Reprogramming Factors and Neural Conditions to Convert Human Dental Pulp Stem Cells into Neural Stem Cells Doctor of Philosophy Doctorate Full Time Miss Maria Roumenova Gancheva
2012 - 2016 Principal Supervisor Epignetic Regulation of Histone Three Lysine Twenty Seven Tri Methylation Dictates Mesenchymal Stem Cell Lineage Commitment, Lifespan and Murine Skeletal Development Doctor of Philosophy Doctorate Full Time Miss Sarah Elizabeth Hemming
2012 - 2016 Co-Supervisor Interleukin-17A Induced Human Mesenchymal Stem Cells are Superior Modulators of Immunological Function Doctor of Philosophy Doctorate Full Time Dr Kisha Nandini Sivanathan
2011 - 2014 Co-Supervisor Mesenchymal Stem Cells for the Treatment of Myocardial Infarction-Induced Ventricular Dysfunction Doctor of Philosophy Doctorate Full Time Dr James David Richardson
2010 - 2015 Co-Supervisor ALPHA-L-IDURONIDASE TRANSDUCED MESENCHYMAL STEM CELLS AS A THERAPY FOR THE TREATMENT OF CNS DEGENERATION IN MUCOPOLYSACCHARIDOSIS TYPE I MICE Doctor of Philosophy Doctorate Full Time Dr Matilda Jackson
2010 - 2010 Co-Supervisor Reprogramming of Human Gingival and Periodontal Ligament Fibroblasts to Pluripotency with Defined Factors Master of Philosophy (Dentistry) Master Full Time Dr Ni-Hung Lin
2010 - 2018 Co-Supervisor The Role of mTORC1 in Mesenchymal Stem Cell Fate Determination, Osteoblast Differentiation and Skeletal Development Doctor of Philosophy Doctorate Part Time Ms Mary Patricia Matthews
2009 - 2013 Principal Supervisor The Role of TWIST-1 in the Regulation of Mesenchymal Stem Cell Growth, Fracture Repair and Bone Loss Doctor of Philosophy Doctorate Full Time Mr Lachlan Cooper
2008 - 2012 Co-Supervisor Isolation and Characterization of Stem Cell Populations in the Periodontium Doctor of Philosophy Doctorate Full Time Miss Jimin Xiong
2006 - 2010 Co-Supervisor The Cardiovascular Reparative Properties of Bone Marrow Mesenchymal Precursor Cells Doctor of Philosophy Doctorate Full Time Prof Peter Psaltis
2006 - 2010 Co-Supervisor Functional and Molecular Characterisation of Mesenchymal Stem Cells Derived from Bone Marrow and Dental Tissues Doctor of Philosophy Doctorate Full Time APrf Danijela Menicanin
2005 - 2009 Co-Supervisor Molecular and Cellular Mechanisms of Increased Angiogenesis in Multiple Myeloma: A Role for CXCL12 Doctor of Philosophy Doctorate Full Time Dr Sally Martin
2003 - 2007 Co-Supervisor Guidance and Neuronal Properties of Dental Pulp Stem Cells Doctor of Philosophy Doctorate Full Time Dr Agnes Arthur
2002 - 2008 Co-Supervisor Ovine Bone Marrow Mesenchymal Stem Cells: Isolation, Characterisation, and Developmental Potential for Application in Growth Plate Cartilage Regeneration Doctor of Philosophy Doctorate Full Time Miss Rosa Mc Carty

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