Associate Professor Peter Psaltis
Grant-Funded Researcher (D)
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Associate Professor Peter James Psaltis - MBBS (Hons), PhD, FRACP, FCSANZ
Assoc. Prof. Peter Psaltis is an Academic Cardiologist and Vascular Biologist. He holds NHMRC Career Development and National Heart Foundation Future Leader Fellowships administered through the Adelaide Medical School. He is Leader of the Heart and Vascular Program, Co-director of the Vascular Research Centre, and Theme Leader within the Lifelong Health Theme at SAHMRI, as well as a consultant Interventional Cardiologist in the Central Adelaide Local Health Network.
He has unique expertise across all three disciplines of basic, translational and clinical research, and leads bench-to-bedside projects spanning topics of developmental, macrophage biology, vascular stem cells, inflammatory regulation of atherosclerosis, pharmacological modification of atherosclerosis and coronary plaque imaging.
Research Overview
Our group undertakes basic, translational, and clinical research on vascular and immune stem cells, macrophage and vascular biology, inflammatory regulators of atherosclerosis, pharmacological modulation of atherosclerosis, biomarkers of coronary artery disease and coronary plaque imaging. We use animal models, cell culture systems and human clinical specimens for research. We employ cutting-edge technologies such as single cell RNA sequencing, multi-coloured flow cytometry and mitochondrial metabolism assays for basic research and optical coherence tomography (OCT) for translational research. We have led and are contributing to multiple clinical trials for clinical research.
Projects available for Honours 2023 and 2024
Project 1
Title: Human EndoMac progenitor cells - Isolation and characterisation
Description: Blood vessel formation is essential for tissue development, growth, and repair. Macrophages and endothelial cells play interlinked roles in blood vessel formation. In adult tissues, these cell types are thought to originate independently of each other. We have discovered unique adult stem cells in mouse tissues termed Endothelial-Macrophage (EndoMac) progenitor cells that give rise to both macrophages and endothelial cells and contribute to blood vessel formation after tissue injury. We have found analogous cells in human tissues. This project aims to isolate, characterise, and investigate the properties of human EndoMac progenitor cells, for therapeutic manipulation.
Project 2
Title: Effect of high glucose on EndoMac progenitor cells
Description: Diabetes impairs wound healing and revascularisation of ischaemic tissue, as hyperglycemia affects blood vessel formation. We have found hyperglycemia to dampen the vasculogenic capacity of mouse EndoMac progenitor cells after tissue injury. This project will investigate the metabolic effects of high glucose on mouse EndoMac progenitor cells and their properties, for pharmacological intervention.
Supervisors: Peter Psaltis, Shiwani Sharma, Sanuri Liyanage
Projects available for: Honours and Masters
Location: South Australian Health and Medical Research Institute, Level 6 South
Research projects start: Semester 1 and 2
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Appointments
Date Position Institution name 2021 - ongoing Theme Leader, Lifelong Health South Australian Health and Medical Research Institute 2021 - ongoing Program Lead, Heart and Vascular Health South Australian Health and Medical Research Institute 2016 - 2020 Deputy Theme Leader, Heart Health Theme South Australian Health and Medical Research Institute 2015 - ongoing Senior Research Fellow, Level C The University of Adelaide 2015 - ongoing Co-Director, Vascular Research Centre South Australian Health and Medical Research Institute 2015 - ongoing Consultant Cardiologist Adelaide Heart Clinic 2015 - ongoing Clinical Academic and Consultant Interventional Cardiologist Central Adelaide Local Health Network 2013 - 2014 Post-doctoral Research Fellow Monash University 2013 - 2014 Interventional Cardiology Fellow Monash Health 2010 - 2014 Post-doctoral Research Fellow University of Adelaide 2010 - 2012 Senior Research Fellow Mayo Clinic, Rochester 2009 - 2012 Post-doctoral Research/Senior Research Fellow Mayo Clinic 2004 - 2014 Senior Lecturer University of Adelaide -
Awards and Achievements
Date Type Title Institution Name Country Amount 2021 Award NHMRC Marshall and Warren Innovation Award, Most Innovative Ideas Grant for 2020 Round National Health and Medical Research Council Australia - 2021 Award Best Cover Paper Journal of Clinical Medicine Australia - 2016 Research Award Best Research Award, 5th International Congress on Lipid Metabolism and Atherosclerosis 5th International Congress on Lipid Metabolism and Atherosclerosis Korea, Republic of - 2013 Recognition Top Ten Abstract Gordon Research Conference - Atherosclerosis, Stowe United States - 2011 Award Early Career Investigator Award (Inaugural), American Heart Association Scientific Sessions Meeting, Orlando, FL, USA Arteriosclerosis Thrombosis and Vascular Biology Council United States - 2011 Award Best Poster Presentation Award, Mayo Research Fellows’ Association Mayo Clinic United States - 2011 Recognition Top Ten Abstract Gordon Research Conference - Atherosclerosis United States - 2009 Award The Ross Wishart Memorial Award for the Best Young Investigator Australian Society of Medical Research Australia - 2009 Award Best mini-oral Presentation - Runner-up Award, Australasian Section, 33rd Annual Scientific Meeting International Society for Heart Research Australia - 2009 Recognition Top 5% Abstract Ranking Cardiac Society of Australia and New Zealand Australia - 2009 Award Nimmo Prize, Best Oral Research Presentation Royal Adelaide Hospital Australia - 2008 Award Best Poster Prize, Research Expo The University of Adelaide Australia - 2007 Award Hugh Gilmore Prize, Best Oral Research Presentation Royal Adelaide Hospital Australia - 2006 Scholarship First ranked application, National Heart Foundation Post-Graduate Scholarship National Heart Foundation Australia - 2004 Teaching Award Outstanding Teaching and Service to Medical Students The University of Adelalaide Australia - 2004 Award Best Registrar Award, Selected by Interns Royal Adelaide Hospital Australia - 2003 Teaching Award Outstanding Teaching and Service to Medical Students The University of Adelaide Australia - -
Education
Date Institution name Country Title 2016 Cardiac Society of Australia and New Zealand Australia Fellowship 2010 University of Adelaide Australia Doctor of Philosophy 2005 Royal Australasian College of Physicians Australia Fellowship (Cardiology and Internal Medicine) 1999 University of Adelaide Australia Bachelor of Medicine, Bachelor of Surgery -
Research Interests
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Journals
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Book Chapters
Year Citation 2022 Carpenter, H. J., Ghayesh, M. H., Zander, A. C., & Psaltis, P. J. (2022). Effect of Nonlinear Blood Viscosity on LDL Transport and Fluid-Structure Interaction Biomechanics of a Multi-stenosis Left Circumflex Coronary Artery. In NODYCON Conference Proceedings Series (pp. 39-48). Springer International Publishing.
DOI2021 Gholipour, A., Carpenter, H. J., Hajghayesh, M. H., Zander, A., & Psaltis, P. J. (2021). Effect of Blood Flow Models on the Flow-Induced Vibrations of Coronary Arteries. In S. Oberst, B. Halkon, & J. Ji (Eds.), Vibration Engineering for a Sustainable Future (Vol. 3, pp. 345-351). Switzerland: Springer International Publishing.
DOI2020 Nankivell, V., Primer, K., Vidanapathirana, A., Psaltis, P., & Bursill, C. (2020). Vascular Biology of Smooth Muscle Cells and Restenosis. In R. Fitridge (Ed.), Mechanisms of Vascular Disease A Textbook for Vascular Specialists (3rd ed., pp. 117-139). Cham, Switzerland: Springer. -
Conference Papers
Year Citation 2024 Aiyar, R., Due, C., Taylor, A., & Sawyer, A. (2024). Help-Seeking and Support for South and Southeast Asian Migrant Caregivers’ Wellbeing in the First 2000 Days: Advancing Health Equity. In Perinatal Society of Australia and New Zealand (PSANZ) 2024 Annual Congress, Whiria te Tāngata “Weave our people together”, 7‐10 April 2024 Vol. 60. Ōtautahi Christchurch, Aotearoa New Zealand: Journal of Paediatrics and Child Health: Wiley.
DOI2024 Sun, R., Wang, H., Xue, M., & Chen, H. T. (2024). PPVR: A Privacy-Preserving Approach for User Behaviors in VR. In Proceedings - 2024 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops, VRW 2024 (pp. 1055-1056). FL, Orlando: IEEE.
DOI2024 Dang, Q., Psaltis, P., Burgess, S., Chandrasekhar, J., Mukherjee, S., Kritharides, L., . . . Zaman, S. (2024). Predictors of Major Adverse Cardiovascular Events: First Report From the Australian-New Zealand Spontaneous Coronary Artery Dissection (ANZ-SCAD) Registry. In Heart Lung and Circulation Vol. 33 (pp. S366-S367). Elsevier BV.
DOI2024 Solly, E. L., Bouman Chen, Z., Luo, Y., Mulangala, J., Di Bartolo, B. A., Nicholls, S. J., . . . Tan, J. T. M. (2024). Inhibition of microRNA-181c-5p rescues diabetes-impaired angiogenesis through activation of key mediators of angiogenesis, cell survival and novel genes, elmo3 and trib1. In EUROPEAN HEART JOURNAL Vol. 45 (pp. 1 page). ENGLAND, London: OXFORD UNIV PRESS.
DOI2023 Liyanage, S., Williamson, A., Salagaras, T., Hassanshahi, M., Long, A., Tran, D., . . . Psaltis, P. (2023). Inhibitory And Metabolic Effects Of Diabetes On Yolk Sacderived Endothelial-macrophage Progenitors In Postnatal Murine Tissues. In ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 43 (pp. 2 pages). PA, Philadelphia: LIPPINCOTT WILLIAMS & WILKINS.
DOI2023 Wang, Y., Deng, J., Hou, Y., Li, Y., Zhang, Y., Ji, J., . . . Zhang, Y. (2023). CluB: Cluster Meets BEV for LiDAR-Based 3D Object Detection. In Advances in Neural Information Processing Systems Vol. 36 (pp. 12 pages). Online: Neural information processing systems foundation. 2022 Solly, E. L., Mulangala, J., Di Bartolo, B. A., Nicholls, S. J., Psaltis, P. J., Bursill, C. A., & Tan, J. T. M. (2022). Inhibition of microRNA-181c rescues diabetes-impaired angiogenesis through activation of key angiogenesis mediators. In DIABETOLOGIA Vol. 65 (pp. S25-S26). Stockholm, SWEDEN: SPRINGER. 2022 Wang, X., Ghayesh, M. H., Kotousov, A., Zander, A. C., & Psaltis, P. J. (2022). Dynamical influences of different aneurysm sizes on rupture risk of abdominal aorta. In Proceedings of the 1st International Conference on Mechanical System Dynamics (ICMSD 2022) Vol. 2022 (pp. 33-38). Hybrid Conference, Nanjing, China: Institution of Engineering and Technology.
DOI Scopus12022 Wang, X., Ghayesh, M. H., Kotousov, A., Zander, A. C., & Psaltis, P. J. (2022). Wall Shear Stress for an Aorta with Aneurysms Via Computational Fluid Dynamics. In Advances in Nonlinear Dynamics. NODYCON Conference Proceedings Series (pp. 27-37). Switzerland: Springer International Publishing.
DOI2021 Carpenter, H. J., Gholipour, A., Hajghayesh, M., Zander, A., & Psaltis, P. J. (2021). Flow-Induced Dynamics of Bifurcated Coronary Arteries. In Vibration Engineering for a Sustainable Future: Numerical and Analytical Methods to Study Dynamical Systems, Vol. 3 (pp. 339-344). Switzerland: Springer International Publishing.
DOI Scopus12021 Heath, S. J., Carpenter, H. J., Ghayesh, M. H., Zander, A. C., & Psaltis, P. J. (2021). Fluid-Elastic Versus Computational Fluid Dynamics Techniques in the Biomechanical Analysis of Coronary Arteries. In 10th Australasian Congress on Applied Mechanics 2021, ACAM 2021 (pp. 686-698). Virtual, Online: Engineers Australia. 2020 Carpenter, H. J., Gholipour, A., Ghayesh, M. H., Zander, A., & Psaltis, P. J. (2020). IN VIVO BASED BIOMECHANICS OF THE LEFT MAIN CORONARY BIFURCATION REGION. In ATHEROSCLEROSIS Vol. 315 (pp. E23). ELSEVIER IRELAND LTD. 2019 Bursill, C., Primer, K. R., Solly, E., Psaltis, P. J., & Tan, J. T. M. (2019). High-density lipoproteins rescue diabetes-impaired angiogenesis by restoring cellular metabolic reprogramming responses to hypoxia. In EUROPEAN HEART JOURNAL Vol. 40 (pp. 337). FRANCE, Paris: OXFORD UNIV PRESS. 2019 Pisaniello, A. D., King, P., Di Bartolo, B. A., Liu, G., Gibson, R. A., Tan, J. T. M., . . . Nicholls, S. (2019). IMPACT OF FISH OIL SUPPLEMENTATION ON ACUTE VASCULAR INFLAMMATION IN HEALTHY VOLUNTEERS. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 73 (pp. 2091). New Orleans, LA: ELSEVIER SCIENCE INC.
DOI2018 Gholipour, A., Ghayesh, M., Zander, A., Nicholls, S., & Psaltis, P. (2018). Fluid-structure analysis of an atherosclerotic coronary artery. In Proceedings of the 21st Australasian Fluid Mechanics Conference (AFMC 2018) (pp. 1-4). Adelaide, Australia: Australian Fluid Mechanics Society. 2018 Akers, E. J., Mulangala, J., Psaltis, P. J., Bursill, C., Nicholls, S. J., & Di Bartolo, B. A. (2018). Lipoproteins and their Modified Forms Regulate Smooth Muscle Cell Calcification. In ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 38 (pp. 2 pages). San Francisco, CA: LIPPINCOTT WILLIAMS & WILKINS.
DOI2018 Mulangala, J., Akers, E. J., Solly, E. L., Psaltis, P. J., Tan, J. T., Nicholls, S. J., . . . Di Bartolo, B. A. (2018). Elevated Calcium Drives Inflammatory-Driven Angiogenesis. In ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 38 (pp. 2 pages). San Francisco, CA: LIPPINCOTT WILLIAMS & WILKINS.
DOI2018 Shanmugam, V. B., & Psaltis, P. (2018). BIFURCATIONAL PERCUTANEOUS CORONARY INTERVENTION IN ST ELEVATION MYOCARDIAL INFARCTION. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 72 (pp. B165). CA, San Diego: ELSEVIER SCIENCE INC. 2018 Shishikura, D., Kataoka, Y., Di Giovanni, G., Janssan, A., Takata, K., Andrews, J., . . . Nicholls, S. (2018). Progression of Plaque Attenuation and Echogenicity Associates With Major Adverse Cardiovascular Events; Insights From Intravascular Ultrasound.. In CIRCULATION Vol. 138 (pp. 2 pages). LIPPINCOTT WILLIAMS & WILKINS. 2018 Rasheed, Z. B. M., Rai, R. K., Anucha, E., Lee, Y. S., Sung, K. H., MacIntyre, D. A., . . . Sykes, L. (2018). TLR3 Priming Increases TLR4-and TLR6-Mediated Pro-Inflammatory Cytokine Production in Amniocytes, Myocytes and Vaginal Epithelial Cells.. In REPRODUCTIVE SCIENCES Vol. 25 (pp. 258A). CA, San Diego: SAGE PUBLICATIONS INC. 2017 Mccoy, P., Macintyre, G., Clarkson, M., Kurganovs, N., Ryan, A., Lunke, S., . . . Hovens, C. (2017). The potential for androgen influenced disruption of the mismatch repair gene Msh2 in Prostate Cancer. In BJU INTERNATIONAL Vol. 120 (pp. 20-21). AUSTRALIA: WILEY. 2017 Shishikura, D. S., Kataoka, Y. K., Honda, S. H., Takata, K. T., Kim, S. K., Andrews, J. A., . . . Nicholls, S. J. N. (2017). The effect of apabetalone on attenuated coronary atherosclerotic plaque: insights from the ASSURE trial. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 232). SPAIN, Barcelona: OXFORD UNIV PRESS. 2017 Takata, K., Honda, S., Sidharta, S., Duong, M., Shishikura, D., Kim, S., . . . Nicholls, S. J. (2017). Association between cholesterol efflux capacity and coronary plaque lipid composition on near infrared spectroscopy. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 467). OXFORD UNIV PRESS. 2017 Honda, S., Kataoka, Y., Shishikura, D., Takata, K., Andrew, J., Butters, J., . . . Nicholls, S. J. (2017). Comparison of plaque microstructures between two high-intensity statin therapies: rosuvastatin versus atorvastatin. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 117-118). Barcelona, SPAIN: OXFORD UNIV PRESS. 2016 Munnur, R. K., McCormick, L., Ko, B., Psaltis, P., Cameron, J., Meredith, I., . . . Wong, D. (2016). DIAGNOSTIC ACCURACY OF ASLA SCORE (A NOVEL CT ANGIOGRAPHIC INDEX) AND AGGREGATE PLAQUE VOLUME IN THE ASSESSMENT OF FUNCTIONAL SIGNIFICANCE OF CORONARY STENOSIS. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 67 (pp. 1673). IL, Chicago: ELSEVIER SCIENCE INC.
DOI2016 Raphael, C. E., Spoon, D., Bell, M., Psaltis, P. J., Kidd, S., Loh, S. X., . . . Gulati, R. (2016). IMPACT OF THROMBOCYTOPENIA ON PROGNOSIS AFTER PERCUTANEOUS CORONARY INTERVENTION. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 67 (pp. 185). IL, Chicago: ELSEVIER SCIENCE INC.
DOI2014 Nerlekar, N., Nasis, A., Ko, B., Leung, M., Cameron, J., Wong, D., . . . Seneviratne, S. (2014). IMPACT OF HEART RATE ON DIAGNOSTIC ACCURACY OF SECOND GENERATION 320-DETECTOR COMPUTED TOMOGRAPHY CORONARY ANGIOGRAPHY. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 63 (pp. A1051). ELSEVIER SCIENCE INC.
DOI2013 Spoon, D. B., Psaltis, P. J., Kidd, S., Prasad, A., Lennon, R., Singh, M., & Gulati, R. (2013). OUTCOMES AFTER PCI IN PATIENTS WITH THROMBOCYTOPENIA. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 61 (pp. E1718). CA, San Francisco: ELSEVIER SCIENCE INC.
DOI2013 Spoon, D. B., Psaltis, P. J., Holmes, D., Simari, R., Gersh, B., Lennon, R., . . . Gulati, R. (2013). TEMPORAL TRENDS IN THE CAUSE OF LONG-TERM DEATH AFTER PCI: A 20-YEAR SINGLE-CENTER EXPERIENCE. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 61 (pp. E1590). CA, San Francisco: ELSEVIER SCIENCE INC.
DOI2013 Spoon, D. B., Psaltis, P. J., Singh, M., Holmes, D. R., Gersh, B. K., Rihal, C. S., . . . Gulati, R. (2013). Trends in Cause of Long-Term Death After Percutaneous Coronary Intervention. In CIRCULATION Vol. 128 (pp. 1 page). TX, Dallas: LIPPINCOTT WILLIAMS & WILKINS. 2012 Spoon, D. B., Psaltis, P. J., Hoffman, S. J., Witt, T. A., Lerman, A., Khosla, S., & Simari, R. D. (2012). Delivery of Osteocalcin (OCN plus ) Expressing Myeloid Cells is Sufficient to Generate Vascular Calcification. In CIRCULATION Vol. 126 (pp. 1 page). LIPPINCOTT WILLIAMS & WILKINS. 2011 Psaltis, P. J., Peterson, K., Xu, R., Franchi, F., Chen, I. Y., Simari, R. D., . . . Rodriguez-Porcel, M. G. (2011). In vivo Imaging of Oxidative Stress in Mesenchymal Stromal Cells Transplanted After Myocardial Ischemia/Reperfusion Injury. In CIRCULATION Vol. 124 (pp. 2 pages). LIPPINCOTT WILLIAMS & WILKINS. 2011 Psaltis, P. J., Harbuzariu, A., Delacroix, S., Witt, T., Kleppe, L., Mueske, C., . . . Simari, R. D. (2011). Sca-1 Identifies a Monocyte-Predisposed Hierarchy of Hematopoietic Progenitor Cells in the Postnatal Murine Aorta. In CIRCULATION Vol. 124 (pp. 1 page). LIPPINCOTT WILLIAMS & WILKINS. 2010 Delacroix, S., Boylan, B. J., Harbuzariu, A., Psaltis, P. J., Pan, S., Holroyd, E., . . . Simari, R. D. (2010). NPR-B Expression In Megakaryocytes and Platelets.. In BLOOD Vol. 116 (pp. 1751-1752). FL, Orlando: AMER SOC HEMATOLOGY. 2010 Harbuzariu, A., Psaltis, P. J., Witt, T. A., Kleppe, L. S., Delacroix, S., Holroyd, E. W., . . . Simari, R. D. (2010). Bone Marrow Mononuclear Cells Contribute to the Vascular Hematopoietic Niche. In CIRCULATION Vol. 122 (pp. 2 pages). LIPPINCOTT WILLIAMS & WILKINS. 2010 Lau, D. H., Carbone, A., Psaltis, P. J., Mackenzie, L., Metcalf, R., Kuklik, P., . . . Sanders, P. (2010). ATRIAL PROTECTIVE EFFECTS OF N-3 POLYUNSATURATED FATTY ACIDS: A LONG TERM STUDY IN OVINE CHRONIC HEART FAILURE. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 55 (pp. 1 page). ELSEVIER SCIENCE INC. 2009 Psaltis, P. J., Worthley, S. G., See, F., Itescu, S., Martens, T., Gronthos, S., & Zannettino, A. (2009). Enrichment for Stro-1 Enhances Paracine-mediated Cardiovascular Repair From Human Bone Marrow Mesenchymal Cells. In CIRCULATION Vol. 120 (pp. S821). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS. 2009 Psaltis, P. J., Carbone, A., Manavis, J., Jantzen, T., Lau, D., Sanders, P., . . . Worthley, S. G. (2009). Catheter-based Electromechanical Mapping Accurately Characterizes Segmental Distribution of Left Ventricular Fibrosis in Nonischemic Cardiomyopathy. In CIRCULATION Vol. 120 (pp. S906). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS. 2009 Psaltis, P. J., Zannettino, A., Carbone, A., Manavis, J., Williams, K., Jantzen, T., . . . Worthley, S. G. (2009). Cardiac Repair With Transendocardial Injection of Allogeneic Mesenchymal Precursor Cells for Nonischemic Cardiomyopathy. In CIRCULATION Vol. 120 (pp. S827). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS. 2007 See, F., Seki, T., Psaltis, P., Martens, T., Gronthos, S., Worthley, S., . . . Itescu, S. (2007). Human stroll mesenchymal precursor cells induce proliferative effects on vascular smooth muscle cells and endothelium via P13 kinase dependent pathways. In CIRCULATION Vol. 116 (pp. 104). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS. 2004 Roberts-Thomson, K. C., Psaltis, P. J., Kee, P., & Young, G. D. (2004). Long term follow up of patients undergoing electrophysiological study on amiodarone. In JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 37 (pp. 264). Brisbane, AUSTRALIA: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. -
Conference Items
Year Citation 2022 Nankivell, V. A., Vidanapathirana, A., Rajora, M., Psaltis, P., Tan, J. T., Tieu, W., . . . Bursill, C. A. (2022). Theranostic Properties of Porphysome Nanoparticles in Atherosclerotic Cardiovascular Disease. Poster session presented at the meeting of CIRCULATION. Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2022 Primer, K. R., Tan, J. T., Psaltis, P. J., & Bursill, C. A. (2022). Pyruvate Dehydrogenase Kinase 4 is a Novel Regulator of Endothelial Cell Mitochondrial Respiration in Diabetes-Impaired Angiogenesis: Implications for Preventing Diabetic Vascular Complications. Poster session presented at the meeting of CIRCULATION. Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2022 Pullen, B. J., Vidanapathirana, A. K., Sandeman, L., Everest-Dass, A., Kolarich, D., Tan, J. T., . . . Bursill, C. A. (2022). Deletion of the Asialyloglycoprotein Receptor-1 Causes Athero-Protective Effects in vitro and in vivo. Poster session presented at the meeting of CIRCULATION. Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2022 Dorraki, M., Liao, Z., Abbott, D., Psaltis, P. J., Baker, E., Bidargaddi, N., . . . Verjans, J. W. (2022). Cardiovascular disease risk prediction via machine learning using mental health data. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. OXFORD UNIV PRESS. 2019 Fernando, S., Schwarz, N., Sandeman, L., Skoumbourdis, T., Zareh, J., Williamson, A., . . . Psaltis, P. J. (2019). Eukaryotic Elongation Factor 2 Kinase Regulates Cholesterol Uptake by Macrophages via Cd36 Scavenger Receptor Expression. Poster session presented at the meeting of CIRCULATION. Philadelphia, PA: LIPPINCOTT WILLIAMS & WILKINS. 2019 Wong, N. K., Solly, E., Nicholls, S., Psaltis, P., Ng, M. K., Bursill, C. A., & Tan, J. T. (2019). <i>TRIM2</i> an<i>d CREBRF</i> Are Novel Regulators of Angiogenic Functions in Human Coronary Artery Endothelial Cells. Poster session presented at the meeting of CIRCULATION. Philadelphia, PA: LIPPINCOTT WILLIAMS & WILKINS. 2019 Williamson, A., Toledo, D. F., Schwarz, N., Fernando, S., Dimasi, C., Liyanage, S., . . . Psaltis, P. J. (2019). Postnatal mouse aorta contains yolk sac-derived haemangioblasts with myeloid and endothelial plasticity and vasculogenic capacity. Poster session presented at the meeting of European Heart Journal. Paris, France: Oxford University Press. 2019 Franke, K., Marshall, H., Worthley, M., & Psaltis, P. J. (2019). A systematic review and meta-analysis on spontaneous coronary artery dissection: epidemiology, risk factors and outcomes. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Paris, FRANCE: OXFORD UNIV PRESS. 2019 Solly, E., Hourigan, S. T., Mulangala, J., Psaltis, P. J., Di Bartolo, B., Martin, N., . . . Tan, J. T. M. (2019). Inhibition of miR-181c Rescues Diabetes-Impaired Angiogenesis. Poster session presented at the meeting of DIABETES. San Francisco, CA: AMER DIABETES ASSOC.
DOI2019 Akers, E. J., Mulangala, J., Wilsdon, L. A., Psaltis, P. J., Bursill, C. A., Nicholls, S. J., & Di Bartolo, B. A. (2019). Lipoproteins and Their Modified Forms Regulate Early Stage Vascular Smooth Muscle Cell Calcification. Poster session presented at the meeting of ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. Boston, MA: LIPPINCOTT WILLIAMS & WILKINS. 2019 Opperman, K., Vandyke, K., Psaltis, P., Croucher, P., Noll, J., & Zannettino, A. (2019). Macrophages as a potential therapeutic target: Clodronate-liposome treatment inhibits multiple myeloma tumour establishment in vivo. Poster session presented at the meeting of CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. CIG MEDIA GROUP, LP.
DOI2018 Takata, K., Duong, M., Honda, S., Sidharta, S. L., Kim, S. W., Shishikura, D., . . . Nicholls, S. J. (2018). Association of Apolipoprotein C-III Distribution With Cholesterol Efflux Capacity and Coronary Plaque Burden. Poster session presented at the meeting of CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. 2017 Pisaniello, A., Di Bartolo, B., Liu, G., Gibson, R., Kim, S., Psaltis, P., & Nicholls, S. (2017). THE IMPACT OF ORAL OMEGA-3 FATTY ACID SUPPLEMENTATION ON ACUTE VASCULAR INFLAMMATION IN A MOUSE MODEL. Poster session presented at the meeting of ATHEROSCLEROSIS. Prague, CZECH REPUBLIC: ELSEVIER IRELAND LTD.
DOI WoS12017 Takata, K., Duong, M., Kim, S., Di Bartolo, B., Butters, J., Mani, P., . . . Nicholls, S. J. (2017). GREATER CIRCULATING CONCENTRATIONS OF LARGE HDL PARTICLES ASSOCIATE WITH MORE FAVORABLE HDL FUNCTIONALITY IN YOUNG ADULTS. Poster session presented at the meeting of ATHEROSCLEROSIS. Prague, CZECH REPUBLIC: ELSEVIER IRELAND LTD.
DOI2017 Shishikura, D., Sidharta, S. L., Honda, S., Takata, K., Kim, S., Andrews, J., . . . Nicholls, S. J. (2017). THE RELATIONSHIP BETWEEN SEGMENTAL WALL SHEAR STRESS AND NIRS-DERIVED LIPID CORE PLAQUE. Poster session presented at the meeting of ATHEROSCLEROSIS. Prague, CZECH REPUBLIC: ELSEVIER IRELAND LTD.
DOI2017 Mulangala, J., Akers, E. J., Psaltis, P. J., Nicholls, S. J., & Di Bartolo, B. A. (2017). Calcium Dose Dependently Influences Endothelial Cell Angiogenesis. Poster session presented at the meeting of ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. Minneapolis, MN: LIPPINCOTT WILLIAMS & WILKINS. 2017 Honda, S., Sidharta, S., Shishikura, D., Takata, K., Andrews, J., Kim, S., . . . Nicholls, S. (2017). GENDER RELATED DIFFERENCES OF SERIAL CHANGE IN CORONARY PLAQUE COMPOSITION. Poster session presented at the meeting of ATHEROSCLEROSIS. Prague, CZECH REPUBLIC: ELSEVIER IRELAND LTD.
DOI2017 Honda, S., Sidharta, S., Shishikura, D., Takata, K., Andrews, J., Kim, S., . . . Nicholls, S. (2017). HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AS A DETERMINANT OF CHANGE IN CORONARY PLAQUE LIPID BURDEN ASSESSED BY NEAR INFRARED SPECTROSCOPY. Poster session presented at the meeting of ATHEROSCLEROSIS. Prague, CZECH REPUBLIC: ELSEVIER IRELAND LTD.
DOI2016 Pullen, B., Nguyen, T., Gosnell, M., Anwer, A., Goldys, E., Nicholls, S., & Psaltis, P. (2016). Label-free assessment of endothelial cell metabolic state using autofluorescent microscopy. Poster session presented at the meeting of Proceedings of SPIE - The International Society for Optical Engineering. SPIE.
DOI2009 Lau, D. H., Mackenzie, L., Kelly, D. J., Psaltis, P. J., Worthington, M., Rajendram, A., . . . Sanders, P. (2009). Hypertension and atrial fibrillation: a long term study of remodeling in a conscious ovine model. Poster session presented at the meeting of Abstracts of the 82nd Scientific Session of the American Heart Association, as published in Circulation. Orlando, FL: American Heart Association. -
Preprint
Year Citation 2024 Nankivell, V., Sandeman, L., Stretton, L., Vidanapathirana, A., Rajora, M., Chen, J., . . . Bursill, C. (2024). Multifunctional biomimetic porphyrin-lipid nanoparticles – novel nanoscale theranostics for atherosclerotic cardiovascular disease.
DOI2024 Primer, K. R., Tan, J. T. M., Sandeman, L., Nankivell, V., Stretton, L. G., Solly, E., . . . Bursill, C. A. (2024). Reconstituted high-density lipoproteins rescue diabetes-impaired endothelial cell metabolic reprograming and angiogenic responses to hypoxia.
DOI
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2021-22 The Hospital Research Foundation Translational Grant (ID C-PJ-004_Transl-2020) |
Peter James Psaltis (CIB) Title: World’s smallest 3D-printed imaging catheter to identify patients at high risk for myocardial infarction and optimise treatments. |
$70,000 |
| 2021-23 National Health and Medical Research Council of Australia, Ideas Grant (ID2001541) |
Peter James Psaltis (CIA) Title: Defining a new player in atherosclerosis: The role of Adventitial Haemangioblasts as an "outside-in" driver of plaque growth and stability. ** Winner of Marshall Warren Innovation Award. |
$728004.50 |
| 2021-24 National Health and Medical Research Council of Australia, Ideas Grant (ID2001646) |
Peter James Psaltis (Associate Investigator) Title: Serial imaging of molecular and microstructural changes in atherosclerosis: tracking plaques towards destabilisation. |
$992,112 |
| 2020-2021 National Heart Foundation of Australia, Vanguard Grant (ID102981) |
Peter James Psaltis (CIA) Title: What role do local stem cells play in atherosclerosis? |
$140,000 |
|
2020-2022 National Health and Medical Research Council of Australia, Development Grant (ID1175142) |
Peter James Psaltis (CIC) Title: Bioinvisible stents – a new device coating to repair cardiovascular disease. |
$671,960 |
| 2020-2024 National Health and Medical Research Council of Australia, Clinical Trials and Cohort Studies (ID1187193) |
Peter James Psaltis (CIJ) Title: COLchicine CARDIovascular Outcomes in Acute Coronary Syndrome (COLCARDIO-ACS) Study. |
$4,238,895.50 |
| 2020-2023 National Health and Medical Research Council of Australia, MRFF (ID1201375) |
Peter James Psaltis (Associate Investigator) Title: Using Polygenic Risk Scores to Target Statin Therapy in Primary Prevention. |
$1,400,000 |
| 2020-2023 National Health and Medical Research Council of Australia, Ideas Grant (ID1184571) |
Peter James Psaltis (Associate Investigator) Title: Novel nanoscale theranostic applications of porphysomes in atherosclerotic cardiovascular disease. |
$632,690 |
| 2020 South Australian Health and Medical Research Institute, seed funding. |
Peter James Psaltis (CIB) Title: Finding disease drivers for atherosclerosis: measurement of autophagic flux in a human cohort. |
$30,000 |
| 2019-2022 National Health and Medical Research Council of Australia, Level 2 Career Development Fellowship (ID1161506) |
Peter James Psaltis (CIA) Title: New approaches to target plaque inflammation in atherosclerosis. |
$386,724 |
| 2019-2022 National Heart Foundation of Australia, Level 2 Future Leaders Fellowship (ID102056) |
Peter James Psaltis (CIA) Title: New approaches to target plaque inflammation in atherosclerosis. |
$200,000 |
| 2018-2020 National Health and Medical Research Council of Australia, Project Grant (ID1142794) |
Peter James Psaltis (CIA) Title: The novel role of Eukaryotic Elongation Factor 2 Kinase (eEF2K) in atherosclerosis. |
$650,531 |
| 2018-2020 National Health and Medical Research Council of Australia, Project Grant (ID1140996) |
Peter James Psaltis (CIC) Title: Bone marrow macrophages: “Resident Evil” in the establishment and progression of multiple myeloma. |
$570,585 |
| 2018-2020 National Health and Medical Research Council of Australia, Project Grant (ID1138917) |
Peter James Psaltis (Associate Investigator) Title: Role for zinc and ZIP2 in the action of nitric oxide and in vascular protection against cigarette smoke and cardiovascular disease. |
$685,940.60 |
| 2018 Sylvia and Charles Viertel Charitable Foundation Clinical Investigator Award (VIERCI2017016) |
Peter James Psaltis (CIA) Title: Colchicine for coronary plaque modification in acute coronary syndrome. |
$85,000 |
| 2018 Royal Australasian College of Physicians, Career Development Fellowship |
Peter James Psaltis (CIA) Title: A Novel Role for Adventital Macrophage Progenitor Cells (AMPCs) in providing a local source of macrophages in atherosclerosis. |
$100,000 |
| 2018 National Heart Foundation of Australia, Tom Simpson Trust Fund |
Peter James Psaltis (CIA)
|
$16,500 |
| 2018 Foundation for Children. Project (ID 289) |
Peter James Psaltis (CIC) Title: Improving the long-term cardio-metabolic health of preterm infants through nutritional interventions: A role for omega-3 fatty acids? |
$124,550 |
| 2017-2020 NHMRC Project Grant (ID 1127159) |
Peter James Psaltis (CIA) Title: A study of the plaque - modifying actions of colchicine in stable and unstable atherosclerosis: from mouse models to clinical imaging |
$1,198,460 |
| 2017 National Heart Foundation of Australia, Vanguard Project Grant (ID 101370) |
Peter James Psaltis (CIA) Title: Colchicine for coronary plaque modification in acute coronary syndrome - A serial optical coherence tomography study |
$75,000 |
| 2017 National Heart Foundation of Australia, Tom Simpson Trust Fund |
Peter James Psaltis (CIA) |
$9,150 |
| 2017 Abbott Vascular Pty Ltd, Research Grant | Peter James Psaltis (CIA) | $10,000 |
| 2016 5th International Congress on Lipid Metabolism and Atherosclerosis, Travel Grant | Peter James Psaltis | $1,500 |
| 2015-2017 NHMRC Project Grant (ID 1086796) |
Peter James Psaltis (CIA) Title: A study of the origins of macrophages in healthy and atherosclerotic vasculature focusing on a novel population of resident adventitial macrophage progenitor cells (AMPCs) |
$451,125.50 |
| 2015-2018 National Heart Foundation of Australia, Future Leadership Fellowship (FLF100412) |
Peter James Psaltis (CIA) Title: Investigating the development of macrophages in atherosclerosis through a novel pathway of resident adventitial macrophage progenitor cells |
$412,000.00 |
| 2014-2020 ARC Centre of Excellence |
Peter James Psaltis (Associate Investigator) Centre for Nanoscale Biophotonics |
$23,000,000 |
| 2010-2014 NHMRC Post-doctoral Overseas Biomedical Fellowship (ID 0627055) |
Peter James Psaltis (CIA) Title: The myelopoietic potential of vascular adventitial progenitor cells (APCs) and their role in atherosclerosis |
$369,519 |
| 2010 Royal Australasian College of Physicians, Marjorie Hooper Overseas Fellowship | Peter James Psaltis | $20,000 |
| 2006-2009 NHMRC (co-funded), Post-graduate Biomedical Scholarship |
Peter James Psaltis Title: A study of the properties of STRO-1 selected mesenchymal stem cells and their potential for cardiac repair |
$110,385 |
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2024 Principal Supervisor The role of coding and non-coding RNA in atherosclerotic plaque phenotype in diabetic vs non-diabetic patients with peripheral arterial disease Doctor of Philosophy Doctorate Part Time Dr Benjamin Thurston 2024 Principal Supervisor The “Can Semaglutide or eMpAgliflozin Stabilise coronary atHerosclerosis after Acute Coronary Syndrome (SMASH-ACS)” study Master of Philosophy (Clinical Science) Master Full Time Miss Momina Ahmed Allahwala 2024 Co-Supervisor Improved classification of cardiovascular plaques in intravascular imaging using deep learning. Doctor of Philosophy Doctorate Full Time Mr Yi Chen 2024 Co-Supervisor Continuous imaging of molecular and microstructural changes in atherosclerosis by a 3d-printed multimodal endoscope Doctor of Philosophy Doctorate Full Time Miss Yujia Kong 2023 Co-Supervisor The role of the asialoglycoprotein receptor-1 in immune cell regulation of atherosclerosis Doctor of Philosophy Doctorate Full Time Mr Demeke Geremew Debebe 2023 Principal Supervisor New Predictive Factors that Drive Coronary Artery Disease Doctor of Philosophy Doctorate Full Time Miss Naomi Elizabeth Wattchow 2023 Co-Supervisor Biomechanical Analysis of Diseased Coronary Arteries Doctor of Philosophy Doctorate Full Time Mr Yaofeng Ju 2021 Principal Supervisor Population Based Studies of Stroke Incidence, Subtypes, Treatments and Outcomes in South Australia Doctor of Philosophy Doctorate Part Time Mr Joshua Mahadevan -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2020 - 2024 Co-Supervisor Nonlinear Biomechanics of Aortic System Doctor of Philosophy Doctorate Full Time Ms Xiaochen Wang 2019 - 2024 Principal Supervisor Applications of Clinical Lipidomics to Metabolic Diseases: Methodology and Implications Doctor of Philosophy Doctorate Full Time Mr Jake White 2019 - 2023 Co-Supervisor Fluid-Structure Interaction for Heart Attack Prediction Doctor of Philosophy Doctorate Full Time Mr Harry James Carpenter 2019 - 2023 Principal Supervisor Inhibitory and metabolic effects of diabetes on yolk sac-derived endothelial-macrophage progenitors in postnatal murine tissues Doctor of Philosophy Doctorate Full Time Ms Sanuri Rashmitha Liyanage 2018 - 2022 Principal Supervisor Discovery and characterisation of yolk-sac derived Endothelial-Macrophage progenitor cells in postnatal murine tissues Doctor of Philosophy Doctorate Full Time Miss Anna Emilie Williamson 2018 - 2019 Co-Supervisor Plaque Rupture Prediction in Human Arteries Doctor of Philosophy Doctorate Full Time Dr Alireza Gholipour 2017 - 2020 Co-Supervisor Control of adipocyte differentiation and metabolism by mitogen-activated protein kinase (MAPK)-interacting kinases (MNKs) Doctor of Philosophy Doctorate Full Time Mr James Edward Merrett 2017 - 2021 Co-Supervisor Macrophages, Myeloma, Mouse Models and Methodologies Doctor of Philosophy Doctorate Full Time Mrs Khatora Shanae Opperman 2017 - 2021 Principal Supervisor Molecular Mediators of Macrophage Foam Cell Formation and Atherosclerosis and their Pharmacological Modification Doctor of Philosophy Doctorate Full Time Ms Sanuja Fernando 2016 - 2022 Co-Supervisor OPTIMISATION OF SURGICAL TIMING IN RHEUMATIC MITRAL VALVE
DISEASEDoctor of Philosophy Doctorate Full Time APrf Ross Roberts-Thomson 2015 - 2020 Co-Supervisor Triglyceride Rich Lipoproteins and Apolipoprotein C-III in Atherosclerosis Doctor of Philosophy Doctorate Full Time Miss Wenru Pan 2008 - 2011 Co-Supervisor The Effects of Omega-3 Fatty Acids in an Ovine Model of Anthracycline-induced Non-ischaemic Cardiomyopathy Master of Medical Science Master Full Time Mr Angelo Carbone
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Board Memberships
Date Role Board name Institution name Country 2018 - ongoing Member Board South Australian Postgraduate Medical Education Association (SAPMEA) Australia -
Committee Memberships
Date Role Committee Institution Country 2020 - ongoing Member Steering Committee NHMRC-funded COLCARDIO-ACS study Australia 2020 - ongoing Member Steering Committee NHMRC-funded Da Vinci study Australia 2020 - ongoing Member Scientific Committee Cardiac Society of Australia and New Zealand Australia 2019 - ongoing Member Leadership Executive Committee, Lifelong Health Theme South Australian Health and Medical Research Institute (SAHMRI) Australia 2018 - ongoing Member Executive Committee Australian Atherosclerosis Society Australia 2017 - ongoing Member Clinical Council Australian Atherosclerosis Society Australia 2017 - ongoing Member National Health and Medical Research Council of Australia, Grant Review Panel - - 2016 - ongoing Member Reconciliation Action Plan (RAP) Committee South Australian Health and Medical Research Institute (SAHMRI) Australia 2016 - ongoing Member Research Executive Committee South Australian Health and Medical Research Institute (SAHMRI) Australia 2016 - ongoing Member Acute Coronary Syndrome Task Force SA Health Australia 2016 - ongoing Member Research Executive Committee South Australian Health and Medical Research Institute (SAHMRI) Australia 2015 - ongoing Member Bioscience Pillar Committee Member South Australian Health and Medical Research Institute (SAHMRI) Australia 2015 - 2016 Member Scientific Program Committee and Interventional Stream Leader, 64th Annual Scientific Meeting Cardiac Society of Australia and New Zealand Australia -
Memberships
Date Role Membership Country 2016 - ongoing Member Cardiac Society of Australia and New Zealand (Fellow) Australia 2016 - ongoing Member Acute Coronary Syndrome Task Force, SA Health Australia 2015 - ongoing Member Australian Cardiovascular Alliance Australia 2014 - ongoing Member International Society for Heart Research Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2015 - ongoing Associate Editor Heart, Lung and Circulation - - 2011 - ongoing Board Member Journal of Geriatric Cardiology - - -
Offices Held
Date Office Name Institution Country 2021 - ongoing Co-lead, Lifelong Health Theme South Australian Health and Medical Research Institute (SAHMRI) Australia 2021 - ongoing Leader, Heart and Vascular Program South Australian Health and Medical Research Institute (SAHMRI) Australia 2020 - ongoing President Australian Atherosclerosis Society Australia 2019 - 2020 Scientific Program Chair, Annual Scientific Meeting Cardiac Society of Australia and New Zealand Australia 2019 - ongoing Principal Site Investigator, NHMRC-funded CAUGHT-CAD study Royal Adelaide Hospital Australia 2018 - ongoing Principal Site Investigator, NHMRC-funded CAUGHT-CAD study Royal Adelaide Hospital Australia 2017 - ongoing Head of Optical Coherence Tomography Imaging Core Laboratory South Australian Health and Medical Research Institute (SAHMRI) Australia 2016 - ongoing National Lead Investigator, CLEAR study ESPERION Therapeutics Australia 2016 - 2020 Deputy Leader, Heart Heath Theme South Australian Health and Medical Research Institute (SAHMRI) Australia 2015 - ongoing Co-director, Vascular Research Centre, Heart Health Theme South Australian Health and Medical Research Institute - 2015 - 2017 Site Investigator, CARAT study Royal Adelaide Hospital Australia
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