Professor Sarah Robertson
NHMRC Ext-Funded Rsch Fellow E
School of Biomedicine
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor Sarah Robertson is a graduate of the University of Adelaide (BSc 1983; PhD 1993). She returned to Adelaide after periods at the University of Alberta (Edmonton, Canada) and University of Gothenburg (Sweden). She was funded as an NHMRC Fellow for 18 years and was an NHMRC Principal Research Fellow until appointment to Director of the Robinson Research Institute in Oct 2013. She stepped down from RRI Director to take up an NHMRC Investigator Award as Professorial Research Fellow in April 2021.
Her research focus is mammalian reproduction and development, particularly immune regulation of fertility and pregnancy. She strives to advance understanding of the fundamental biology of conception, embryo implantation and early development, to develop biologically rational approaches for managing 'unexplained' infertility and common pregnancy disorders. She partnered with Origio A/S to develop EmbryoGen, a novel immune-based intervention for repeated IVF failure and recurrent miscarriage now sold in >50 countries worldwide, and with industry partners is investigating novel strategies to tackle early pregnancy loss, preeclampsia, preterm delivery and stillbirth.
She is an elected Fellow of the Australian Academy of Science (2016) and the Australian Academy of Health and Medical Sciences (2015), and a Fellow of the Society for Reproductive Biology (2011). In 2024 she was awarded Officer of the Order of Australia (AO) for distinguished service to medical research, particularly reproductive biology and immunology and to professional societies.
Her work is funded by the National Health and Medical Research Council of Australia, the Australian Research Council, the Canadian Institutes of Health Research, and the Channel 7 Children's Research Foundation. Her research output includes more than 250 peer-reviewed scientific journal papers and reviews in high impact journals, >20 book chapters and 5 patent families. Her H-index is 87 with >23,300 citations (Google Scholar, August 2024).
She serves in professional roles for the NHMRC, Australian Academy of Science, Australian Academy for Health and Medical Science, Ramaciotti Foundations, International Society for Immunology of Reproduction, and US Society for the Study of Reproduction.
She collaborates extensively with colleagues in Australia and around the world and has supervised 36 PhD students (29 completed) plus 48 Honours students. For the period of 2008-2013 she was Editor-in-Chief of the Journal of Reproductive Immunology and now serves on the Editorial Boards of Endocrinology, Immunology and Cell Biology, and Clinical and Translational Immunology, as well as the Board of Consulting Editors of the Journal of Clinical Investigation. She regularly contributes to peer review for the NHMRC, ARC, and many international funding agencies.
In 2020 Professor Robertson secured a $3.5M L2 Investigator Grant from the NHMRC (2021-2025) for research on "Peri-conception determinants of reproductive and pregnancy health". She was awarded the 2020 NHMRC Elizabeth Blackburn Investigator Grant Award given annually to the highest ranked female recipient (Leadership category, Basic Science) in the Investigator Grants scheme.
- My Research
- Career
- Publications
- Grants and Funding
- Teaching
- Supervision
- Professional Activities
- Contact
Research Interests
Keywords: reproductive immunology; uterine endometrium; conception; embryo implantation; female reproductive function; female response to seminal fluid; seminal plasma; pregnancy complications; female infertility; recurrent pregnancy loss; preterm birth; preeclampsia.
Research in the Reproductive Immunology group centres on four related themes:
• Mechanisms of immune control of female reproduction and pregnancy
• The impact of pregnancy tolerance perturbation on embryo implantation, placental development, pregnancy progression and offspring outcomes
• Defining immune causes of infertility and pregnancy complications, and developing diagnostic tools and immune-targeting interventions;
• Male seminal fluid factors that influence female pregnancy tolerance and cryptic female choice.
Research projects
1. The immune response and endometrial receptivity
Certain types of immune cells are essential for female immune tolerance of implantation and pregnancy, while others can suppress implantation and pregnancy. Uterine macrophages and dendritic cells are master regulators of tolerance, through generating regulatory T cells that suppress inflammation, prevent maternal immune rejection of the conceptus, and facilitate robust placental development. Our projects use mouse models to investigate the functions and behavior of regulatory T cells, macrophages and dendritic cells in unique mechanisms for generating tolerance at the outset of pregnancy. Additionally, these cells have tissue remodelling functions and communicate within cell networks to impact endometrial receptivity for decidualisation and embryo implantation, and placental development. Specific immune-regulatory agents including cytokines, microRNAs and TLR ligands contribute to these events and their significance is evaluated in genetic mouse models.
2. Understanding and treating immune causes of infertility and pregnancy loss
With our clinical partners, we evaluate the relationship between immune status and fertility, and are identifying T cell signatures associated with recurrent implantation failure and early pregnancy loss in women. A focus is to distinguish different subtypes of immune disorder that constrain conception and healthy pregnancy, based on peripheral blood markers that indicate impaired tolerance, elevated inflammation, and/or immune dysfunction secondary to altered metabolic status. A specific challenge is to identify and evaluate immune interventions that boost immune tolerance, such as low dose IL-2, with potential for safe and effective use in women where an impaired immune response is implicated in reproductive and pregnancy disorders. Although various immune interventions are proposed to be useful in human infertility, our studies and others demonstrate these are often ineffective when used in unselected patient populations - so a key challenge is to develop the tools to better match treatments to individual patient needs in a precision medicine approach.
3. Priming the female immune response for conception and pregnancy
We are interested in the female response to seminal fluid, and its significance for fertility and reproductive health. Seminal fluid has a profound effect on female tract immune parameters and is a key factor in establishing local immune adaptations that allow conception, receptivity to embryo implantation and progression of pregnancy. This is mediated by male transplantation antigens and immune-regulatory factors that promote generation of regulatory T cells. The immune changes induced by seminal fluid are critical for fertility and pregnancy health, and can also impact sexually transmitted infection, and conditions including infertility, recurrent miscarriage, and endometriosis. We focus on defining the molecular identity of sperm and seminal plasma signalling molecules, and characterising the immune response elicited in female tissues. The physiological consequences of the female tract response for fertility and embryo development, as well as infection and immune defence, are studied.
4. Seminal fluid factors and reproductive health in women
In women, seminal fluid induces cellular changes and an induction of inflammatory cytokines similar to the response in mice and other animals. The cytokine and chemokine regulation of the cervical and uterine response in women can be modelled in in vitro experiments, or studied in tissue biopsies. We are identifying the active signalling factors in human seminal fluid, and investigating how these impact fertility and pregnancy outcomes in the human IVF setting. We are also examining the relationship between the seminal fluid content of individual signalling components, fertility and health status, and age and lifestyle factors in men. This work has potential to deliver new immune-based diagnostics and treatment interventions for male infertility.
5. Cytokine regulation of embryo development
Cytokines originating from the maternal oviduct and uterine epithelium act to regulate the development of the embryo as it traverses the reproductive tract prior to implantation. Cytokines modulate gene expression, and cell survival and differentiation, to synchronise embryo growth and development with uterine receptivity. Some years ago we discovered an important role for GM-CSF in promoting blastocyst development, implantation and placental formation, to ultimately affect fetal growth and offspring health after birth. In humans, we showed GM-CSF suppresses cell stress and promotes development of healthy blastocysts. In partnership with Origio A/S, we conducted clinical trials in IVF patients to show GM-CSF improves implantation success especially after prior miscarriage. Our work resulted in the product Embryogen, now sold in 50 countries worldwide. Our current studies are exploring how specific maternal tract cytokines exert both positive and negative effects on preimplantation embryos, to program implantation competence, fetal development and health of offspring after birth.
-
Appointments
Date Position Institution name 2021 - ongoing NHMRC Investigator Fellow University of Adelaide 2013 - 2021 Director University of Adelaide 2010 - ongoing Professor of Reproductive Immunology The University of Adelaide 2010 - 2013 Principal Research Fellow National Health and Medical Research Council (NHMRC) 2008 - 2013 Co-Director Research Centre for Reproductive Health 2000 - ongoing Research Leader: Reproductive Immunology Research Group University of Adelaide -
Awards and Achievements
Date Type Title Institution Name Country Amount 2024 Award Officer of the Order of Australia Australian Government Australia - 2023 Award International Society for Immunology of Reproduction Mentoring Award (Asia-Pacific Region) International Society for Immunology of Reproduction Germany - 2023 Distinction Distinguished Scientist Award of the Society of Reproductive Investigation Society for Reproductive Investigation United States - 2022 Award Channel 7 Children’s Research Foundation Award for Outstanding Achievement in Children’s Health Research, Australia Channel 7 Children’s Research Foundation Australia - 2022 Award American Society for the Immunology of Reproduction AJRI Award American Society for the Immunology of Reproduction United States - 2022 Award 2022 SSR Distinguished Fellowship Award Society for the Study of Reproduction United States - 2020 Award 2020 NHMRC Elizabeth Blackburn Investigator Grant Award (Leadership in Basic Science) National Health and Medical Research Council Australia - 2020 Award Society for Reproductive Investigation Mentoring Award Society for Reproductive Investigation United States - 2016 Fellowship Fellow of the Australian Academy of Science Australian Academy of Science Australia - 2015 Invitation Louis Waller Lecture Victorian Assisted Reproductive Treatment Authority Australia - 2015 Achievement Elected Fellow, Australian Academy of Health and Medical Sciences - - - 2014 Award Finalist, SA Scientist of the Year - - - 2014 Award Raymond O. Berry Lecture Texas A&M University United States - 2013 Award Senior Investigator Award European Society for Reproductive Immunology Australia - 2013 Award Founder's Lecturer Society for Reproductive Biology Australia - 2012 Award AWT Edwards Orator, Australian Health and Medical Research Congress (2012) Australian Health and Medical Research Congress Australia - 2012 Award Director's Award Robinson Research Institute Australia - 2011 Fellowship Fellow of the Society for Reproductive Biology Society for Reproductive Biology Australia - -
Education
Date Institution name Country Title 1993 University of Adelaide Australia PhD 1983 University of Adelaide Australia B.Sc. -
Research Interests
-
Journals
-
Book Chapters
Year Citation 2023 Grieger, J. A., Moran, L. J., Robertson, S. A., Wang, R., & Norman, R. J. (2023). LIFESTYLE, PERICONCEPTION, AND FERTILITY. In Textbook of Assisted Reproductive Techniques: Volume 2: Clinical Perspectives, Sixth Edition (Vol. 2, pp. 366-375). CRC Press.
DOI2021 Redman, C. W. G., Robertson, S. A., & Taylor, R. N. (2021). The Immunology of Preeclampsia. In R. N. Taylor, K. P. Conrad, S. T. Davidge, A. C. Staff, & J. M. Roberts (Eds.), Chesley’s Hypertensive Disorders in Pregnancy (5 ed., pp. 131-153). Elsevier.
DOI Scopus12019 Sharkey, D. J., & Robertson, S. A. (2019). Sex and immune receptivity for embryo transfer. In G. Kovacs, & L. Salamonsen (Eds.), How to prepare the endometrium to maximize implantation rates and IVF success (pp. 151-158). Cambridge, UK: Cambridge University Press.
DOI Scopus12018 Schjenken, J. E., Sharkey, D. J., & Robertson, S. A. (2018). Seminal vesicle-Secretion. In M. K. Skinner (Ed.), Encyclopedia of Reproduction (pp. 349-354). Academic Press.
DOI Scopus62018 Schjenken, J. E., Sharkey, D. J., & Robertson, S. A. (2018). Seminal Vesicle—Secretion. In Encyclopedia of Reproduction: Volume 1-6, Second Edition (Vol. 1, pp. 349-354).
DOI2017 Norman, R. J., Moran, L. J., Robertson, S. A., & Wang, R. (2017). Lifestyle, periconception, and fertility. In Textbook of Assisted Reproductive Techniques, Fifth Edition: Two Volume Set (pp. 434-443). 2016 Fullston, T., Shehadeh, H., Schjenken, J. E., McPherson, N. O., Robertson, S. A., Zander-Fox, D., & Lane, M. (2016). Paternal obesity and programming of offspring health. In L. R. Green, & R. L. Hester (Eds.), Parental Obesity: Intergenerational Programming and Consequences (1 ed., pp. 105-131). New York, NY: Springer.
DOI2015 Robertson, S., Chin, P. -Y., Schjenken, J., & Thompson, J. (2015). Female tract cytokines and developmental programming in embryos. In H. Leese, & D. Brison (Eds.), Cell signalling during mammalian early embryo development (Vol. 843, 1 ed., pp. 173-213). New York: Springer.
DOI Scopus42 WoS27 Europe PMC172015 Schjenken, J., & Robertson, S. (2015). Seminal fluid signalling in the female reproductive tract: Implications for reproductive success and offspring health. In R. Bronson (Ed.), The Male Role in Pregnancy Loss and Embryo Implantation Failure (Vol. 868, pp. 127-158). Switzerland: Springer.
DOI Scopus61 WoS52 Europe PMC432015 Robertson, S. A., Sharkey, D. J., Schjenken, J. E., Care, A. S., & Moldenhauer, L. M. (2015). Pathways for activating implantation tolerance in early pregnancy.. In G. CHAOUAT (Ed.), Immunology of Pregnancy (Vol. 2, pp. 1835-1874). Bentham Science Publishers.
DOI Scopus352014 Robertson, S., & Thompson, J. (2014). Growth factors and cytokines in embryo development. In P. Quinn (Ed.), Culture Media, Solutions, and Systems in Human ART, 2014 (1 ed., pp. 112-131). United Kingdom: Cambridge University Press.
DOI Scopus22008 Robertson, S. A. (2008). Cytokine and chemokine regulation of endometrial immunobiology. In The Endometrium: Molecular, Cellular and Clinical Perspectives, Second Edition (pp. 546-569).
Scopus32006 Robertson, S., Bromfield, J., Glynn, D., Sharkey, D., & Jasper, M. (2006). Actions of seminal plasma cytokines in priming female reproductive tract receptivity for embryo implantation. In Gil Mor (Ed.), Immunology of Pregnancy (pp. 148-158). New York: Springer.
DOI2006 Thompson, J., Lane, M., & Robertson, S. (2006). Adaptive responses of early embryos to their microenvironment and consequences for post-implantation development. In Unknown Book (Vol. 573, pp. 58-69). Kluwer Academic / Plenum Publ.
Scopus7 WoS62002 Robertson, S., & Hudson Keenihan, S. (2002). Cytokines: Pivotal regulators of endometrial immunobiology. In S. Glasser, J. Aplin, L. Giudice, & S. Tabibzadeh (Eds.), The endometrium (pp. 416-433). 11 New Fetter Lane, London EC4P 4EE: Taylor & Francis. 1999 Tremellen, K., & Robertson, S. (1999). Seminal 'Priming' for Successful Mammalian Pregnancy. In Reproductive Immunology (pp. 88-98). Narosa Publishing House. 1998 Robertson, S. (1998). Cytokines. In Encyclopedia of Reproduction (pp. 809-822). Academic Press.
DOI -
Conference Papers
Year Citation 2024 Robertson, S. A., Groome, H. M., Peck, C. Y., Roberts, C. T., & Care, A. S. (2024). Macrophages Are Essential Regulators of Uterine Vascular Adaptation during Early Pregnancy in Mice.. In REPRODUCTIVE SCIENCES Vol. 31 (pp. 93A). CANADA, Vancouver: SPRINGER HEIDELBERG. 2024 Foyle, K. L., Moldenhauer, L. M., Ferguson, G. D., Robertson, S. A., & Care, A. S. (2024). Boosting Maternal Regulatory T Cells in Pregnancy Using IL-2 Antibody Complex Protects Against Fetal Loss in Mice.. In REPRODUCTIVE SCIENCES Vol. 31 (pp. 189A). CANADA, Vancouver: SPRINGER HEIDELBERG. 2023 Lovell, E., Hosking, S., Groome, H., Parry, L., Robertson, S., & Care, A. (2023). MATERNAL C1Q DEFICIENCY LEADS TO IMPAIRED DECIDUAL VASCULAR REMODELLING, PLACENTAL INSUFFICIENCY AND REDUCED FETAL GROWTH. In PLACENTA Vol. 140 (pp. E30). NEW ZEALAND, Rotorua: W B SAUNDERS CO LTD. 2023 Winship, A., Griffiths, M., Marshall, S., Cousins, F., Alesi, L., Higgins, J., . . . Hutt, K. (2023). Radiotherapy Exposure Directly Damages the Uterus and Causes Pregnancy Loss. In REPRODUCTIVE SCIENCES Vol. 30 (pp. 83A). AUSTRALIA, Brisbane: SPRINGER HEIDELBERG. 2023 Sharkey, D. J., & Robertson, S. A. (2023). The role of seminal plasma in supporting successful embryo implantation. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 158 (pp. 1 page). FRANCE, Paris: ELSEVIER IRELAND LTD.
DOI2023 Sharkey, D. J., & Robertson, S. A. (2023). Seminal fluid and the female immune response - an update on the male contribution to pregnancy beyond fertilisation. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 159 (pp. 12-13). ELECTR NETWORK: ELSEVIER IRELAND LTD.
DOI2023 Lovell, E. A., Hosking, S. L., Fitzgerald, R. J., Nicholas, L. M., Parry, L. J., Robertson, S. A., & Care, A. S. (2023). Effect of Regulatory T Cell Depletion in Early Pregnancy on Postpartum Cardio- Metabolic Function in Mice. In REPRODUCTIVE SCIENCES Vol. 30 (pp. 227A-228A). AUSTRALIA, Brisbane: SPRINGER HEIDELBERG. 2023 Moldenhauer, L. M., Linthwaite, S., Foyle, K. L., Sharkey, D. J., McCormack, C. D., Robertson, S. A., & Hull, M. L. (2023). Elevated Insulin and Insulin Resistance is Associated with Altered T Regulatory Cell Parameters in Women with Recurrent Miscarriage. In REPRODUCTIVE SCIENCES Vol. 30 (pp. 98A). Brisbane, AUSTRALIA: SPRINGER HEIDELBERG. 2023 Walker, J. R., Foyle, K. L., Moldenhauer, L. M., & Robertson, S. A. (2023). Regulatory T Cell Deficiency in Periconception Impairs Late Gestation Pregnancy Outcomes and Increases Susceptibility to Inflammation Induced Preterm Birth in Mice. In REPRODUCTIVE SCIENCES Vol. 30 (pp. 49A). Brisbane, AUSTRALIA: SPRINGER HEIDELBERG. 2022 Caruso, J., Miller, C., Crabb, S., Wilson, S., Middleton, P., Room, R., . . . Bowden, J. (2022). Are Australians aware of the risks of drinking during pregnancy and breastfeeding? Results of a baseline survey prior to a national campaign. In DRUG AND ALCOHOL REVIEW Vol. 41 (pp. S38). WILEY. 2022 Mukherjee, A., Robertson, S., & Carden, C. (2022). How has the management of acute biliary pathology changed as a result of the SARS CoV2 pandemic?. In BJS-BRITISH JOURNAL OF SURGERY Vol. 109 (pp. 1 page). ENGLAND, Liverpool: OXFORD UNIV PRESS.
DOI2020 Nunez, K., Robertson, S., Cherry, J., Cooper, E. S., Thevenot, P., Cohen, A., & Alquist, C. (2020). Donor and Recipient Flow Crossmatch Positivity is Associated with Increased Risk of Acute Rejection in Simultaneous Liver-Kidney Transplantations. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 20 (pp. 60). FL, Miami: WILEY. 2020 Prairie, E., Loiselle, S. -E., Vermette-Lacroix, F., Hou, X., Sierra, E. M., Quiniou, C., . . . Chemtob, S. (2020). A Novel Allosteric Modulator of IL-6R Successfully Prevents Deleterious Effects of Inflammation in a LPS Model of Preterm Birth.. In REPRODUCTIVE SCIENCES Vol. 27 (pp. 88A). Vancouver, CANADA: SPRINGER HEIDELBERG. 2019 Arthurs, A., Lumbers, E., de Meaultsart, C. C., Robertson, S., Schjenken, J., & Pringle, K. (2019). MIR-155 REGULATES PLACENTAL DEVELOPMENT AND FETAL GROWTH, PROBABLY BY INHIBITING THE EXPRESSION OF ANGIOTENSIN II TYPE 1 RECEPTOR (AT(1)R). In PLACENTA Vol. 83 (pp. E98-E99). Tokyo, JAPAN: W B SAUNDERS CO LTD.
DOI2019 Prairie, E., Loiselle, S. -E., Hou, X., Nadeau-Vallee, M., Sierra, E. M., Quiniou, C., . . . Chemtob, S. (2019). Antenatal Administration of a Potential Interleukin-6 Antagonist Prevents Inflammation-Induced Preterm Birth and Fetal Tissue Injury.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 214A-215A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2019 Nunez, K., Robertson, S., Cherry, J., Cooper, S., Thevenot, P., Cohen, A. J., & Alquist, C. (2019). DONOR SPECIFIC ANTIBODY IN SIMULTANEOUS LIVER-KIDNEY TRANSPLANTATION: PREFORMED CLASS II HLA ANTIBODIES AND ACUTE RENAL AND HEPATIC ALLOGRAFT REJECTION. In HEPATOLOGY Vol. 70 (pp. 706A). MA, Boston: WILEY. 2019 Nunez, K., Sandow, T., Robertson, S., Cohen, A., & Thevenot, P. (2019). Synthetic Liver Function and Absolute Lymphocyte Count in HCC Patients is Associated with Poor Tumor Response to Locoregional Therapy and Increases in Immunosuppressive Cell Populations. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 19 (pp. 73). FL, Miami: WILEY. 2019 Nunez, K., Sandow, T., Robertson, S., Thevenot, P., & Cohen, A. (2019). Modified BALAD Score Predicts Incomplete Locoregional Therapy Treatment in Hepatocellular Carcinoma Patients. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 19 (pp. 72-73). FL, Miami: WILEY. 2019 Groome, H. M., Care, A. S., Chin, P. Y., Roberts, C. T., & Robertson, S. A. (2019). Macrophage Regulation of Decidual Vascular Remodelling is Crucial for Pregnancy Success in Mice.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 202A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2019 Kieffer, E. C., Chin, P. Y., Green, E. S., Moldenhauer, L. M., Prins, J. R., & Robertson, S. A. (2019). Prednisolone Treatment in Early Pregnancy Disrupts Maternal Immune Adaptation and Alters Pregnancy Outcomes in Mice.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 291A-292A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2019 Green, E. S., Moldenhauer, L. M., McColl, S. M., & Robertson, S. A. (2019). Regulatory T Cells are a Key Agent of Progesterone Effects in Early Pregnancy.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 118A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2019 Panir, K., Schjenken, J. E., Breen, J., Greaves, E., Robertson, S. A., & Hull, M. L. (2019). Lesion Development in Endometriosis is Regulated by <i>miR</i>-<i>223</i> Mediated Macrophage Activity.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 375A-376A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2019 Care, A. S., Bourque, S. L., Morton, J. S., Hjartarson, E. P., Humphries, J., Davidge, S. T., & Robertson, S. A. (2019). Regulatory T Cell Deficiency Increases Resistance to Uteroplacental Blood Flow, Leading to Fetal Growth Restriction.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 116A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2018 Robertson, S. A., Zhang, B., Barry, S. C., Schjenken, J. E., & Moldenhauer, L. M. (2018). miRNA-155 is required to induce competent regulatory T cells and to protect against inflammation-induced fetal loss in mice. In CLINICAL ENDOCRINOLOGY Vol. 89 (pp. 36-37). Perth, AUSTRALIA: WILEY. 2016 Robertson, S. A., Zhang, B., Wahid, H. H., & Moldenhauer, L. M. (2016). Repeated priming with male seminal fluid expands regulatory T cell populations to build pregnancy tolerance in mice. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 48). Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2016 Care, A. S., Bourque, S. L., Hjartarson, E. P., Robertson, S. A., & Davidge, S. T. (2016). Effect of Regulatory T Cell Depletion on Uterine Artery Function in the Mouse.. In REPRODUCTIVE SCIENCES Vol. 23 (pp. 221A-222A). Montreal, CANADA: SAGE PUBLICATIONS INC. 2016 Robertson, S., Zhang, B., Moldenhauer, L., & Schjenken, J. (2016). MicroRNA regulation of endometrial macrophages and DCs at conception. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 115 (pp. 50-51). Erfurt, GERMANY: ELSEVIER IRELAND LTD.
DOI2016 Green, E., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Progesterone control of regulatory T cell phenotype and abundance in pregnancy - A novel role for non-classical progesterone action. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 115 (pp. 43). Erfurt, GERMANY: ELSEVIER IRELAND LTD.
DOI2016 Scott, N. M., Jones, A. C., Lauzon-Joset, J. -F., Mincham, K. T., Troy, N. M., Prescott, S. L., . . . Strickland, D. H. (2016). Protection of mother and fetus against bacterial infection induced complications via prophylactic treatment during pregnancy with a microbial-derived immunomodulator. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 1266-1267). Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2016 Koullali, B., Kamphuis, E. I., de Groot, C. J. M., Pajkrt, E., Hof, M. H. P., Robertson, S., . . . Ravelli, A. C. J. (2016). Spontaneous preterm birth rates among unselected women in their first and second pregnancy. In AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY Vol. 214 (pp. S345). Atlanta, GA: MOSBY-ELSEVIER.
DOI2015 Koullali, B., Kamphuis, E., de Groot, C., Pajkrt, E., Hof, M., Robertson, S., . . . Ravelli, A. (2015). Can variation of the interval between the first and second pregnancy be used as a therapeutic strategy to reduce recurrent spontaneous preterm birth?. In AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY Vol. 212 (pp. S12). San Diego, CA: MOSBY-ELSEVIER.
DOI2011 Moldenhauer, L. M., Keenihan, S. N., Hayball, J. D., & Robertson, S. A. (2011). GM-CSF regulates uterine dendritic cell and macrophage maturation and antigen presentation. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 90 (pp. 134-135). Copenhagen, DENMARK: ELSEVIER IRELAND LTD.
DOI WoS22011 Chin, P. Y., Thompson, J. G., & Robertson, S. A. (2011). Maternal Interleukin-10 Deficiency Increases Sensitivity to Adverse Programming Effects of a Low Dose LPS Insult in the Pre-Implantation Period.. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION. 2011 Robertson, S. A. (2011). Basic science to clinical application-the utility of GM-CSF in reproductive medicine. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 90 (pp. 132-133). Copenhagen, DENMARK: ELSEVIER IRELAND LTD.
DOI WoS12010 Chin, P. Y., Thompson, J. G., & Robertson, S. A. (2010). Programming embryo development with a pre-implantation inflammatory insult. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 86 (pp. 39). Palm Grove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI WoS12009 Robertson, S. A. (2009). Immune regulation of embryo implantation-all about quality control?. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 81 (pp. 113-114). Marathon, GREECE: ELSEVIER IRELAND LTD.
DOI2008 Robertson, S., Jasper, M., Bromfield, J., Care, A., Nakamura, H., & Ingman, W. (2008). The role of macrophages in implantation and early pregnancy success. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 274-275). Kailua Kona, HI: SOC STUDY REPRODUCTION.
DOI WoS32008 Sharkey, D., & Robertson, S. (2008). Follistatin mRNA expression is regulated by seminal fluid TGFβ in human Ect1 cervical epithelial cells. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 97-98). Kona, HI: SOC STUDY REPRODUCTION.
DOI WoS12008 Robertson, S., Moldenhauer, L., & Hayball, J. (2008). GMCSF is an essential regulator of uterine dendritic cells in early pregnancy. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 197). Kona, HI: SOC STUDY REPRODUCTION.
DOI WoS32008 Glynn, D., & Robertson, S. (2008). LPS introduced at mating regulates KC production in the murine uterus during early pregnancy. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 136). Kona, HI: SOC STUDY REPRODUCTION.
DOI2008 Sharkey, D., & Robertson, S. (2008). Identification of TGFβ as a major active factor mediating seminal fluid signalling in human cervical epithelial cells. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 284). Kailua Kona, HI: SOC STUDY REPRODUCTION.
DOI WoS12008 Robertson, S. A., Zaragoza, D., Christiaens, I., & Olson, D. M. (2008). Effects of interleukin-6 (IL-6) null mutation on molecular regulation of parturition in mice.. In REPRODUCTIVE SCIENCES Vol. 15 (pp. 266A-267A). San Diego, CA: SAGE PUBLICATIONS INC. 2007 Bromfield, J., & Robertson, S. (2007). Semen exposure regulates lymphangiogeneis in the peri-implanation mouse uterus.. In BIOLOGY OF REPRODUCTION Vol. 77 (pp. 122). San Antonio, TX: SOC STUDY REPRODUCTION.
DOI2006 Robertson, S., O'Leary, S., & Armstrong, D. (2006). Influence of semen on inflammatory modulators of embryo implantation. In C. Ashworth, & R. Kraeling (Eds.), Control of Pig Reproduction VII Vol. 62 (pp. 231-246). UK: Nottingham University Press.
Scopus28 Europe PMC202004 Sivaramakrishnan, G., Jasper, M., O'Leary, S., & Robertson, S. (2004). Probiotic Lactobacillus in seminal plasma.. In Annual Conference of the Society for. Reproductive Biology. ESA & SRB Annual Scientific Meeting, 22-25 August, 2004. Sydney NSW. 2004 Shi, T., Robertson, S., Roberts, C., Beijering, D., Pensa, K., Sheng, Y., & Krilis, S. (2004). Effect of β<sub>2</sub>-glycoprotein I null mutation on reproductive outcome and antiphospholipid antibody-mediated pregnancy pathology in mice. In THROMBOSIS RESEARCH Vol. 114 (pp. 608). Sydney, AUSTRALIA: PERGAMON-ELSEVIER SCIENCE LTD. 2004 Jasper, M., Tremellen, K., & Robertson, S. (2004). Reduced endometrial expression of IL-6 mRNA during the secretory phase of the menstrual cycle is associated with recurrent spontaneous abortion (RSA).. In BIOLOGY OF REPRODUCTION (pp. 211). Univ British Columbia, Vancouver, CANADA: SOC STUDY REPRODUCTION. 2001 Jasper, M. J., O'Leary, S., Armstrong, D. T., & Robertson, S. A. (2001). Seminal plasma-induced expression of cytokine mRNA in pig endometrium during early pregnancy. In P. D. Cranwell (Ed.), MANIPULATING PIG PRODUCTION VIII, PROCEEDINGS Vol. 8 (pp. 198). ADELAIDE, AUSTRALIA: AUSTRALASIAN PIG SCIENCE ASSOC. 2001 O'Leary, S., Armstrong, D., & Robertson, S. (2001). Intrauterine seminal plasma increases ovarian steroidogenesis during early pregnancy in the pig. In P. Cranwell (Ed.), Manipulating pig production VIII : proceedings of the eighth biennial conference of the Australasian Pig Science Association (APSA), 25-28 November, 2001 / P.D. Cranwell (ed.), vol. VIII, pp. 190 Vol. 8 (pp. 190). Adelaide, South Australia: Australasian Pig Science Association.
WoS32001 O'Leary, S., Robertson, S., & Armstrong, D. (2001). Seminal plasma treatment stimulates progesterone synthesis during early pregnancy in the pig. In Proceedingsof the thirty-second annual conference of the Sociey for Reproductive Biology. Australia: CSIRO. 2001 O'Leary, S., Jasper, M., Armstrong, D., & Robertson, S. (2001). Cytokine and Cox-2 mRNA expression in pig endometrium during early pregnancy. In 32nd Annual Conference of the Society for Reproductive Biology. Australia: CSIRO. 2001 O'Leary, S., Robertson, S., & Armstrong, D. (2001). Intrauterine seminal plasma increases ovarian steroidogenesis in the pig. In Society for the Study of Reproduction, 34th Annual Meeting Vol. 2001 (pp. 236). Ottawa, Canada: SOC STUDY REPRODUCTION. 1999 O'Leary, S., Armstrong, D. T., Warnes, G. M., Kamai, R. R. C., & Robertson, S. A. (1999). Seminal plasma induces a local inflammatory response in the reproductive tract of gilts. In P. D. Cranwell (Ed.), MANIPULATING PIG PRODUCTION VII, PROCEEDINGS Vol. 7 (pp. 103). ADELAIDE, AUSTRALIA: AUSTRALASIAN PIG SCIENCE ASSOC.
WoS21999 Armstrong, D. T., O'Leary, S., Gilchrist, R. B., Young, F. M., Wames, G. M., & Robertson, S. A. (1999). Effects of intrauterine seminal plasma on responses of pig follicles to gonadotrophic hormones and growth factors. In P. D. Cranwell (Ed.), MANIPULATING PIG PRODUCTION VII, PROCEEDINGS Vol. 7 (pp. 102). ADELAIDE, AUSTRALIA: AUSTRALASIAN PIG SCIENCE ASSOC. 1993 ROBERTSON, S. A., MAYRHOFER, G., & SEAMARK, R. F. (1993). EPITHELIAL-CELL CYTOKINE SYNTHESIS IN THE PREIMPLANTATION RODENT UTERUS. In F. Dondero, & P. M. Johnson (Eds.), REPRODUCTIVE IMMUNOLOGY Vol. 97 (pp. 117-121). ROME, ITALY: RAVEN PRESS. 1992 Seamark, R. F., Hadjisavas, M., & Robertson, S. A. (1992). Influence of the immune system on reproductive function. In Animal Reproduction Science Vol. 28 (pp. 171-178). HAGUE, NETHERLANDS: ELSEVIER SCIENCE BV.
DOI Scopus8 WoS91991 ROBERTSON, S. A., LAVRANOS, T., & SEAMARK, R. F. (1991). INVITRO MODELS OF THE MATERNAL-FETAL INTERFACE. In T. G. WEGMANN, T. J. GILL, & E. NISBETBROWN (Eds.), MOLECULAR AND CELLULAR IMMUNOBIOLOGY OF THE MATERNAL FETAL INTERFACE (pp. 191-206). BANFF CTR CONTINUING EDUC, BANFF, CANADA: OXFORD UNIV PRESS.
WoS371991 ROBERTSON, S. A., & SEAMARK, R. F. (1991). UTERINE GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR IN EARLY-PREGNANCY - CELLULAR-ORIGIN AND POTENTIAL REGULATORS. In G. CHAOUAT, & J. MOWBRAY (Eds.), CELLULAR AND MOLECULAR BIOLOGY OF THE MATERNO-FETAL RELATIONSHIP Vol. 212 (pp. 113-121). PARIS, FRANCE: INST NATL SANTE RECHERCHE MEDICALE.
WoS12 -
Conference Items
Year Citation 2024 Lovell, E. A., Hosking, S. L., Wooldridge, A. L., De Poi, R. J., Nicholas, L. M., Parry, L. J., . . . Care, A. S. (2024). Maternal Regulatory T Cells Are an Early Pregnancy Determinant of Cardiometabolic Health in Adult Mouse Offspring. Poster session presented at the meeting of Abstracts of the 71st Annual Meeting of the Society for Reproductive Investigation (SRI 2024), as published in Reproductive Sciences. Vancouver, BC, Canada: Springer.
DOI2023 Hosking, S. L., Groome, H. M., Moldenhauer, L. M., Roberts, C. T., Davidge, S. T., Robertson, S. A., & Care, A. S. (2023). Regulatory T Cells Promote Decidual Arterial Remodeling to Facilitate Fetal Development in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. AUSTRALIA, Brisbane: SPRINGER HEIDELBERG. 2023 Tran, H., Chan, H. Y., Adelson, D. L., & Robertson, S. A. (2023). Seminal fluid histocompatibility antigens contribute to T cell priming after mating in mice. Poster session presented at the meeting of Society of Reproductive Biology. Brisbane. 2023 Robertson, S. A., Foyle, K. L., Moldenhauer, L. M., Wong, Y. Y., Green, E. S., Barry, S. C., & Hull, M. L. (2023). Lineage infidelity underpinningregulatory T cell deficiency in recurrent pregnancy loss. Poster session presented at the meeting of Abstracts of the XV World Congress of the International Society for Immunology of Reproduction (ISIR 2023), as published in Journal of Reproductive Immunology. Hamburg, Germny: Elsevier BV.
DOI2022 Chan, H. Y., Tran, H. M., Breen, J., Schjenken, J., & Robertson, S. (2022). The endometrial transcriptome transition preceding receptivity to embryo implantation in mice. Poster session presented at the meeting of Society of Reproduction. Christchurch, New Zealand. 2020 Robertson, S. A., Schjenken, J. S., Moldenhauer, L. M., Zhang, B., Groome, H. M., Chan, H. Y., & Care, A. S. (2020). miR-155 Deficiency Impairs Pregnancy Tolerance and Predisposes to Inflammation-Induced Fetal Loss in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG. 2020 Ho, R. M., Yin, C. P., Robertson, S. A., Hutchinson, M. L., & Keelan, J. A. (2020). Comparative Effects of TLR4 Inhibitors on Inflammatory Activation in Human Decidual Cells.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG. 2020 Care, A. S., Groome, H. M., Hosking, S. L., Roberts, C. T., Davidge, S. T., & Robertson, S. A. (2020). Regulatory T Cells Determine Uterine Natural Killer Cell Abundance and Decidual Vascular Remodeling in Early Pregnancy in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG. 2020 Garcia-Flores, V., Romero, R., Xu, Y., Miller, D., Slutsky, R., Robertson, S. A., & Gomez-Lopez, N. (2020). M2-polarized macrophages as a potential cell therapy to mitigate inflammation-induced preterm birth. Poster session presented at the meeting of JOURNAL OF IMMUNOLOGY. Honolulu, HI: AMER ASSOC IMMUNOLOGISTS.
WoS12019 Care, A., Bourque, S. L., Morton, J. S., Hjartarson, E. P., Humphries, J., Davidge, S. T., & Robertson, S. A. (2019). Regulatory T cell deficiency increases resistance to uteroplacental blood flow, leading to fetal growth restriction. Poster session presented at the meeting of Reproductive Sciences. 2018 Robertson, S. A., Sharkey, D. J., Tremellen, K. P., & Dekker, G. A. (2018). Interferon-G in seminal fluid - An 'anti-tolerance' signal in women?. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Aalborg, DENMARK: ELSEVIER IRELAND LTD.
DOI2018 Robertson, S. A., Green, E. S., McColl, S. R., & Moldenhauer, L. M. (2018). Peri-Implantation Progesterone Determines Regulatory T Cell Competence to Impact Late Gestation Pregnancy Outcome in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. San Diego, CA: SAGE PUBLICATIONS INC. 2018 Care, A. S., Bourque, S. L., Morton, J. S., Hjartarson, E. P., Robertson, S. A., & Davidge, S. T. (2018). Regulatory T Cells Regulate Uterine Artery Function to Impact Fetal. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. San Diego, CA: SAGE PUBLICATIONS INC. 2018 Green, E. S., Moldenhauer, L. M., McColl, S. R., & Robertson, S. A. (2018). Reduced progesterone signalling at implantation compromises Treg cell tolerance and impairs fetal growth and viability in later gestation. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. Perth, AUSTRALIA: WILEY.
WoS12017 Nadeau-Vallee, M., Chin, P. -Y., Belarbi, L., Brien, M. -E., Pundir, S., Beaudry-Richard, A., . . . Chemtob, S. (2017). Antenatal Suppression of Interleukin-1 Protects Against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2017 Wahid, H. H., Moldenhauer, L. M., Rice, K. C., Hutchison, M. R., & Robertson, S. A. (2017). Platelet Activating Factor (PAF) Induces Preterm Birth in Mice Through TLR4-Dependant Induction of Pro-Inflammatory Cytokines.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC.
WoS22017 Nadeau-Vallee, M., Chin, P. -Y., Belarbi, L., Brien, M. -E., Pundir, S., Berryer, M. H., . . . Chemtob, S. (2017). PROTECTIVE EFFECT OF A NOVEL NONCOMPETITIVE IL-1 RECEPTOR-BIASED LIGAND IN AN INFECTION-AND INFLAMMATION-INDUCED PRETERM BIRTH AS WELL AS IN FETAL INJURY AND DEVELOPMENTAL OUTCOMES. Poster session presented at the meeting of ACTA PAEDIATRICA. WILEY. 2016 Scott, N. M., Jones, A. C., Lauzon-Joset, J. F., Mincham, K. T., Troy, N. M., Prescott, S. L., . . . Strickland, D. H. (2016). Protection of mother and fetus against bacterial infection induced complications via prophylactic treatment during pregnancy with a microbial-derived immunomodulator. Poster session presented at the meeting of Abstract of the International Congress of Immunology (ICI 2016), as published in European Journal of Immunology. Melbourne, AUSTRALIA: Wiley-Blackwell.
DOI2016 Green, E. S., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Regulatory T cell abundance and phenotype in pregnancy - a novel role for progesterone potentially independent of nuclear progesterone receptor. Poster session presented at the meeting of EUROPEAN JOURNAL OF IMMUNOLOGY. Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2016 Moore, S., Valtanen, G. P., Robertson, S., Hayball, J., & Diener, K. (2016). The influence of viral infection on the innate immune system during pregnancy. Poster session presented at the meeting of EUROPEAN JOURNAL OF IMMUNOLOGY. Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2015 Kamphuis, E., Koullali, B., Hof, M., de Groot, C., Kazemier, B., Mol, B. W., & Ravelli, A. (2015). Fetal gender of the first born and the recurrent risk of spontaneous preterm birth. Poster session presented at the meeting of AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. San Diego, CA: MOSBY-ELSEVIER.
DOI WoS22015 Schjenken, J., Hewson, L., Zhang, B., & Robertson, S. (2015). THE ROLE OF MICRORNA MIR223 IN IMMUNE ADAPTATION FOR PREGNANCY AND FETAL-PLACENTAL DEVELOPMENT. Poster session presented at the meeting of PLACENTA. W B SAUNDERS CO LTD.
DOI WoS22015 Mial, T. M., Kot, C., Robertson, S. A., & Gomez-Lopez, N. (2015). A Reduction of Macrophage Populations at the Maternal-Fetal Interface in an Infectious, But Not in a Non-Infectious, Model of Preterm Birth.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. SAGE PUBLICATIONS INC. 2015 Robertson, S. A. (2015). IMMUNOMODULATION IN IMPLANTATION. Poster session presented at the meeting of PLACENTA. Mar del Plata, ARGENTINA: W B SAUNDERS CO LTD.
DOI2014 Gomez-Lopez, N., Mial, T., & Robertson, S. (2014). Infection-induced preterm delivery does not involve macrophage M2-M1 polarization. Poster session presented at the meeting of JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. 2014 Robertson, S. A. (2014). Cytokines as mediators of cryptic female choice in the pen-conceptional environment. Poster session presented at the meeting of Abstracts of the 11th Congress of the European Society for Immunology of Reproduction. Budapest, Hungary: Elsevier.
DOI2014 Prins, J. R., Guerin, L. R., Zhang, B., Schjenken, J. E., Barry, S. C., & Robertson, S. A. (2014). Interleukin-10 deficiency causes dysregulation of the regulatory T cell response to pregnancy in mice. Poster session presented at the meeting of Reproductive Sciences. Florence, Italy: SAGE Publications.
DOI2014 Robertson, S. A., Gomez-Lopez, N., Diener, K., Bijland, M. T., Chin, P. -Y., & Olson, D. M. (2014). Essential Role for Macrophages in Late Gestation Pregnancy to Prevent Spontaneous Preterm Birth in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. 2014 Robertson, S. A., Chin, P. -Y., Dorian, C., & Hutchinson, M. (2014). Inhibition of the TLR4 Signalling Pathway Protects Mice from LPS-Induced Preterm Delivery. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. 2014 Robertson, S. A., Wahid, H. W., Dorian, C., Hutchinson, M., & Olson, D. M. (2014). Toll-Like Receptor 4 (TLR4) Signalling Is Implicated in Normal On-Time Labour in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. 2013 Schjenken, J. E., & Robertson, S. A. (2013). Induction of endogenous miR223 expression by sperm in the female reproductive tract following mating in mice. Poster session presented at the meeting of American Journal of Reproductive Immunology. Shanghai, China: John Wiley & Sons.
DOI WoS22013 Robertson, S. A., Wahid, H. H., Harun, N., Zhang, B., & Moldenhauer, L. M. (2013). Repeated Coital Exposure to Male Seminal Fluid Progressively Builds Tolerogenic Regulatory T Cell Populations in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2013 Johan, M. Z., Ingman, W. V., Robertson, S. A., & Hull, M. L. (2013). Activation Status of Macrophages in Lesions from a <i>MacGreen</i>/SCID Mouse Model of Endometriosis. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2013 Gomez-Lopez, N., Bijland, M. T., Olson, D. M., & Robertson, S. A. (2013). Maternal Monocyte-Derived Cell Depletion Promotes Preterm Delivery in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2013 Gomez-Lopez, N., Olson, D. M., & Robertson, S. A. (2013). IL6 Regulates Decidual T Cell Phenotypes To Restore Parturition in IL6 KO Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2012 Yao, Y., Fang, X., Robertson, S., Filkowski, J., Metz, G., Kovalchuk, I., & Olson, D. (2012). Global expression profile in uterine tissue of IL-6-/- and IL6+/+ mice at different stages of gestation and postpartum. Poster session presented at the meeting of Scientific Abstracts of the 59th Annual Scientific Meeting, as published in Reproductive Sciences. SAGE Publications.
DOI2012 Hodyl, N., Scheil, W., Stark, M., & Clifton, V. (2012). Maternal asthma is a significant contributor to neonatal morbidity. Poster session presented at the meeting of Scientific Abstracts of the 59th Annual Scientific Meeting, as published in Reproductive Sciences. San Diego, CA: SAGE Publications.
DOI2012 Gomez-Lopez, N., Dorian, C. L., & Robertson, S. (2012). Parturition Delay in Interleukin-6 Null Mutant Mice Is Not Linked with Gross Alterations in Leukocyte Subsets in the Maternal Periphery, Uterus or Decidual Tissues at Term Gestation.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. San Diego, CA: SAGE PUBLICATIONS INC. 2012 O'Leary, S., Armstrong, D., & Robertson, S. (2012). Presence of immune modulating molecules in boar seminal plasma. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Hamburg, GERMANY: ELSEVIER IRELAND LTD.
DOI2012 Yao, Y., Fang, X., Gomez-Lopez, N., Robertson, S. A., Goldman, S., Shalev, E., . . . Olson, D. M. (2012). Uterine progesterone receptor B (PRB) promotor DNA is methylated in delivering mice. Poster session presented at the meeting of Scientific Abstracts of the 59th Annual Scientific Meeting, as published in Reproductive Sciences. SAGE Publications.
DOI2011 Robertson, S. A., Harun, N., & Moldenhauer, L. M. (2011). Repeated Seminal Fluid Exposure Expands Regulatory T Cell Populations in Mice. Poster session presented at the meeting of BIOLOGY OF REPRODUCTION. Portland, OR: SOC STUDY REPRODUCTION. 2011 Schjenken, J. E., & Robertson, S. A. (2011). Sperm-borne miRNAs: a regulatory role in the endometrium following mating?. Poster session presented at the meeting of Biology of Reproduction. Portland, Oregon: Society for the Study of Reproduction.
DOI2010 Robertson, S. A. (2010). Tolerance or rejection: the immune contribution to embryo-endometrial harmony. Poster session presented at the meeting of Abstracts of the Second International Conference on Reproductive Immunology, Shanghai, China, 28 November-2 December 2010, as published in American Journal of Reproductive Immunology. Shanghai, China: Wiley-Blackwell.
DOI2010 Robertson, S. A. (2010). The immune response to pregnancy: the uncharted territory. Poster session presented at the meeting of Abstracts of the 8th European Congress on Reproductive Immunology, as published in Journal of Reproductive Immunology. Munich, Germany: Elsevier.
DOI2010 Robertson, S. A. (2010). Predicting embryo-endometrial harmony. Poster session presented at the meeting of Abstracts of the 29th Annual Scientific Meeting of The Fertility Society of Australia, as published in Australian and New Zealand Journal of Obstetrics and Gynaecology. Adelaide, South Australia: Wiley-Blackwell.
DOI2010 Ingman, W. V., Chua, A. C. L., Hodson, L. J., & Robertson, S. A. (2010). Novel roles for macrophages in epithelial cell turnover in the cycling adult mammary gland. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Palm Grove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI2010 Lloyd, M. L., Papadimitiou, J. M., O Leary, S., Robertson, S. A., & Shellam, G. R. (2010). The physiological consequences of exposure to zona pellucida 3 antibody in the mouse ovary. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Palm Cove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI2010 Jasper, M. J., Care, A. S., Sullivan, B., Ingman, W. V., Aplin, J. D., & Robertson, S. A. (2010). Uterine epithelial cell fucosylated structures are regulated by macrophages during early pregnancy in mouse. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Palm Grove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI2010 Guerin, L. R., Moldenhauer, L. M., Prins, J., Bromfield, J. D. J., Hayball, J. D., & Robertson, S. A. (2010). Seminal fluid regulates the uterine Foxp3<SUP>+</SUP> T regulatory cell population through CCL19-mediated recruitment during the pen-implantation period in mice. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Palm Cove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI2010 Sharkey, D. J., & Robertson, S. A. (2010). TGFβ superfamily members BMP-15, GDF-9 and Activin A act as seminal fluid signalling agents in human cervical epithelial cells. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Palm Cove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI2010 Sharkey, D. J., & Robertson, S. A. (2010). Sperm and seminal plasma differentially regulate cytokine and chemokine protein expression by human cervical epithelial cells. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Palm Cove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI2010 Christiaens, I., Dorian, C., Olson, D. M., & Robertson, S. A. (2010). Interleukin-6 regulates the timing of birth in mice through a direct uterine effect. Poster session presented at the meeting of Scientific abstracts of the 57th Annual Scientific Meeting, as published in Reproductive Sciences. Orlando, FL: SAGE Publications.
DOI2010 Care, A. S., Jasper, M. J., Ingman, W. V., & Robertson, S. A. (2010). Macrophages are essential for maintenance of corpus luteum function in early pregnancy. Poster session presented at the meeting of Meeting Abstracts, as published in Biology of Reproduction. Milwaukee, Wisconsin: Society for the Study of Reproduction. 2009 Moldenhauer, L. M., Hayball, J. D., & Robertson, S. A. (2009). Immune-deviating cytokines determine the maternal T cell response and conceptus tolerance or rejection. Poster session presented at the meeting of Abstracts of the 42nd Annual Meeting of the Society for the Study of Reproduction, as published in Biology of Reproduction. Pittsburgh, PA: Society for the Study of Reproduction.
WoS22009 Ingman, W. V., Chua, A. C. L., Clark, L. J., & Robertson, S. A. (2009). Key roles for macrophages in the proliferation, differentiation, and phagocytosis of epithetial cells in the mammary gland of cycling mice. Poster session presented at the meeting of Abstracts of the 42nd Annual Meeting of the Society for the Study of Reproduction, as published in Biology of Reproduction. Pittsburgh, PA: Society for the Study of Reproduction. 2006 Olson, D. M., Zaragoza, D. B., Makino, S., Christiaens, I., Robertson, S. A., & Mitchell, B. F. (2006). Inflammatory processes in parturition. Poster session presented at the meeting of Keynote Presentations, as published in Journal of Reproductive Immunology. Banff, Canada: Elsevier Ireland.
DOI2006 Moldenhauer, L. M., Hayball, J. D., & Robertson, S. A. (2006). Conceptus antigens activate the maternal immune response in pregnancy utilising maternal antigen presenting cells. Poster session presented at the meeting of Abstracts of the 3rd International Conference on Experimental and Clinical Reproductive Immunobiology, as published in Journal of Reproductive Immunology. Banff, Canada: Elsevier.
DOI WoS22006 Robertson, S. A., Guerin, L. R., & Bromfield, J. J. (2006). Male seminal constituents activate expansion of the T regulatory cell pool in early pregnancy. Poster session presented at the meeting of Abstracts of the 3rd International Conference on Experimental and Clinical Reproductive Immunobiology, as published in Journal of Reproductive Immunology. Banff, Canada: Elsevier.
DOI WoS41997 Tremellen, K. P., & Robertson, S. A. (1997). Potential role of seminal plasma TGFβ, in the initiation of the post-coital inflammatory response in humans. Poster session presented at the meeting of Abstracts of the 1st International Conference on Experimental and Clinical Reproductive Immunobiology, as published in Journal of Reproductive Immunology. Charlottesville, Virginia: Elsevier.
DOI Scopus51997 Jasper, M., Robertson, S., & Norman, R. J. (1997). Ovarian function in the GM-CSF deficient mouse. Poster session presented at the meeting of Abstracts of the 1st International Conference on Experimental and Clinical Reproductive Immunobiology, as published in Journal of Reproductive Immunology. Charlottesville, Virginia: Elsevier.
DOI -
Patents
Year Citation 2023 Robertson, S., Rasi Ghaemi, S., Sharkey, D., McPherson, N., & Vasilev, K. (2023). PCT/AU2024/050764, SPERM SORTING DEVICE AND METHOD. Australia. 2013 Robertson, S., Wikland, M., & Sjoblom, C. (2013). 2331890, Method and medium for invitro culture of human embryos. Canada. 2007 Robertson, S., Sjoblom, C., & Wikland, M. (2007). 1088057, Method and Medium for In vitro Culture of Human Embryos. Europe. 2006 Robertson, S., & Tremellen, K. (2006). 1028743, Treatment of infertility using TGF-beta or Activin. Europe. 2004 Robertson, S., Sharkey, D., Tremellen, K., & Glynn, D. (2004). WO/2004/026333, Treatment and diagnosis of a reproductive disorder by measuring or inhibiting interferon-&gammad. Australia. -
Figures
Year Citation - Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Toll-like receptor-4 antagonist (+)-naloxone elicits sexually dimorphic attenuation of inflammation-induced fetal programming in mice. Supplemental Figure 1.
DOI- Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Effect of Toll-like receptor-4 antagonist (+)-naloxone and LPS challenge on gestation length, litter size and early post-natal survival and growth..
DOI -
Filesets
Year Citation - Nisenblat, V., Sharkey, D., Wang, Z., Evans, S., HEALEY, M., Ohlsson-Teague, E. M. C., . . . Hull, L. (n.d.). Supplementary Material from: Plasma microRNAs display limited potential as diagnostic tools for endometriosis.
DOI -
Media
Year Citation - Norman, R., Fernandez, R., Schjenken, J., & Robertson, S. (n.d.). Making Babies in the 21st Century.
DOI
Research Grants - Current
National and International Competitive Schemes
| Date | Project/No. | Amount |
|---|---|---|
| 2022-2025 | Peri-conception determinants of reproductive and pregnancy health CI-A NHMRC Investigator Grant APP1198172 |
$3,560,000 |
| 2022-2024 | The immune response as a determinant of female reproductive investment CI-A ARC Discovery DP220103487 |
$629,916 |
| 2021-2024 | Prevention of preterm birth and fetal inflammation: the pharmacology and toxicology of targeting IL-6 with HSJ633, a small peptide allosteric IL6 receptor antagonist CI-E with Olson D, Chemtob S, Hebert T, Lubell W |
$310,590 |
| 2019-2021 | Seminal fluid interferon-gamma – an inhibitor of reproductive success? CI-A ARC Discovery Grant DP190103694 |
$490,000 |
| 2018-2021 | The male partner contribution to pregnancy immune tolerance deficit in women CI-A with Tremellen KP, Lane M, Sharkey D, Barry SC, Dekker G. NHMRC Project Grant APP1139509 |
$1,462,925 |
| 2018-2020 | Preclinical development of TLR signalling inhibitors for prevention of preterm labour and fetal inflammatory injury CI-A with Keelan J and Hutchinson MR. NHMRC Project Grant APP1140916 |
$690,821 |
| 2018-2021 | Preclinical evaluation of a novel allosteric IL1R inhibitor (rytvela) for the prevention of perinatal inflammation-induced fetal injury CI-C with Keelan J, Olson D, Kemp M, Dickinson H. NHMRC Project Grant APP1145295 |
$1,377,827 |
| 2016-2019 | Priming the maternal immune response to resist inflammatory disorders of pregnancy CI-A with Barry SC and Hutchinson MR. NHMRC Project Grant APP1099461 |
$920,972 |
| 2017-2019 |
Impact of Phthalate exposure in fathers on programming of offspring neurological phenotype? CI-A Channel 7 Childrens Medical Research Foundation |
$70,000 |
|---|
| 2018-2024 | A randomised controlled feasibility trial of the mechanism of the fertility enhancing effect of lipiodol CI-B with Johnson N, Guerbet Pharmaceuticals P/L |
$608,223 |
|---|---|---|
| 2017-2019 | Boosting Treg cells with novel immune-regulatory agents for pregnancy success? CI-A Ferring Pharmaceuticals P/L |
$204,914 |
Research Grants - Past
International Competitive Schemes
| Date | Project/No. | Amount |
|---|---|---|
| 2012-2014 | The pivotal roles of IL1B and IL6 in the timing of birth Co-investigator C with Olson DM and Chemtob S Canadian Institutes of Health Research Operating Grant |
CAN $610,000 |
| 2012-2015 | Inflammatory Pathways to Preterm Birth Co-investigator C with Olson DM, Chemtob S, Lubell W, Metz G, Mitchell B Global Alliance for the Prevention of Prematurity and Stillbirth (USA), Preventing Preterm Birth Initiative – Gates Foundation |
US $1.5M |
| 2003-2007 | How do oocytes and embryos cope with adverse environments? Co-investigator H with Thompson JG, Edwards L, Gilchrist RB, Kaye P, Kind K, Pantaleon M, Roberts CT, National Institutes of Health (NIH) USA, #HD-02-018 |
US 1.28M |
Past National Competitive Schemes - Fellowships
| Date | Project/No. | Amount |
|---|---|---|
| 2010-2014 | CI-A NHMRC Research Fellowship (Principal Research Fellow) ID627017 | $752,500 |
| 2005–2009 | CI-A NHMRC Research Fellowship ID349490 | $635,000 |
| 2003–2004 | Seminal transforming growth factor (TGF)β, maternal immune tolerance and pregnancy outcome – promotion out of synchrony CI-A NHMRC Research Fellowship 250450 |
$249,500 |
| 2000–2002 | Seminal transforming growth factor (TGF)β, maternal immune tolerance and pregnancy outcome CI-A NHMRC Research Fellowship 158069 |
$246,000 |
| 1996-2000 | Cytokine-leukocyte networks in early mammalian pregnancy CI-A NHMRC R Douglas Wright Award 977745 |
$201,000 |
Past National Competitive Schemes – Program and Project
| Date | Project/No. | Amount |
|---|---|---|
| 2016-2018 | Sperm signalling in the female reproductive tract - a new biological paradigm CI-A ARC Discovery Grant DP16102366 |
$433,100 |
| 2015-2018 | Inflammatory cytokines as causal agents in peri-conception programming of offspring health CI-A with Thompson JG and Brown H. NHMRC Project Grant APP1079150 |
$585,276 |
| 2015-2017 | Achieving targeted delivery of drugs to uterine muscle in women for the prevention of preterm labour CI-C with Smith, R., Hua, S., Ho, R., Adams Waldorf, K. NHMRC Project Grant APP1099461 |
$469,000 |
| 2013-2016 | Activating T cell tolerance to prevent preeclampsia in women CI-A with Dekker G. NHMRC Project Grant APP1041332 |
$610,045 |
| 2013-2015 | Reducing susceptibility to allergic asthma in offspring by immunomodulatory therapy of the pregnant mother CI-C with Strickland D and Prescott S. NHMRC Project Grant APP1041764 |
$430,300 |
| 2012-2014 | Inflammatory pathways for novel therapeutic intervention in preterm delivery CI-A with Hutchinson MH and Olson DM. NHMRC Project Grant APP1026178 |
$525,000 |
| 2009-2011 | Seminal fluid and reproductive health in women CI-A with Quayle AJ, NHMRC Project Grant 565368 |
$450,000 |
| 2009-2011 | Mechanisms of seminal fluid signalling in mammals CI-A with RB Gilchrist, ARC Discovery Grant DP0986882 |
$470,000 |
| 2007–2011 | Periconceptual Foundations for a Healthy Start to Life CI-B with Norman RJ, Rogers RJ, Thompson JG, Lane M, Dekker G, Davies M, NHMRC Program Grant 453556 |
$10.2 million |
| 2006-2008 | Macrophage-regulated tissue remodelling in endometrial receptivity for embryo implantation and pregnancy success CI-A with Roberts CT, NHMRC Project Grant 399105 |
$445,250 |
| 2005-2006 | Seminal plasma cytokines as novel fertility diagnostics in men CI-A with Tremellen KP, Norman RJ, NHMRC Development Grant 399106 |
$101,000 |
| 2005-2007 | Mechanisms of infertility induced in mice by vaccination with murine ZP3 CI-B with GR Shellam, ARC Discovery Grant |
$220,000 |
| 2005-2009 | Network in Genes and Environment in Development Convenor RI Richards + 46 other participants, Australian Research Council / NHMRC Research Network #RN0457079 |
$1.5 million |
| 2003-2007 | Reproductive health in women CI-D with Norman RJ, Rodgers RJ, Armstrong DT, Thompson JG NHMRC Program Grant 250306 |
$8.2 million |
| 2003-2005 | GM-CSF regulation of pre-implantation embryo development CI-A with Thompson JG, NHMRC Development Grant 250388 |
$480,000 |
| 2002-2004 | The mechanistic basis of a reproductive lesion in TGFβ null mutant mice CI-A, ARC Discovery Grant |
$292,000 |
| 2000-2002 | Seminal transforming growth factor (TGF)β, maternal immune tolerance and pregnancy outcome CI-A with RF Seamark and JS Robinson, NHMRC Project Grant 104837: 5 year award (2000-2004) |
$195,000 |
| 2000-2002 | Effects of leptin on follicle growth and development CI-C with Norman RJ, Armstrong DT and Owens PC NHMRC Project Grant 104813 |
$327,000 |
| 1997-1999 | Seminal plasma and sperm as determinants of the maternal immune response to pregnancy CI-A with RF Seamark, JS Robinson NHMRC Project Grant 970070 |
$195,000 |
| 1997-1999 | Colony stimulating factors in ovulation and luteal function CI-C with RJ Norman, SR Maddocks, AM Dharmarajan NHMRC Project Grant 970069 |
$199,000 |
| 1995-1997 | Regulation of chorionic gonadotrophin expression and secretion in the marmoset monkey CI-C with RJ Norman and A Lopata ARC Large Grant #A09531907 |
$217,000 |
| 1994-1996 | The role of uterine epithelial cell-derived cytokines in reproduction, CI-A with RF Seamark, NHMRC Project Grant 940339 |
$282,000 |
Past Industry and Consulting Income
| Date | Project/No. | Amount |
|---|---|---|
| 2017-2019 | Boosting Treg cells with novel immune-regulatory agents for pregnancy success CI-A, Ferring Pharmaceuticals |
USD $155,733 |
| 2003-2004 | PV903 product testing in animal models CI-A, Gropep Pty. Ltd |
$46,708 |
| 2002-2003 | Cytokine index / bacterial load in semen as a determinant of boar fertility CI-A, Australian Pork Limited ID1831 |
$107,251 |
| 2001-2002 | Development of an assay for immune status in pregnancy CI-A, Gropep Pty. Ltd |
$124,000 |
| 2000-2001 | Interleukin-6 and interleukin-10 as cofactors in induction of reproductive tract immunity CI-A, Pest Animal Control CRC |
$20,000 |
| 2000-2001 | Insemination as a vehicle for induction of immunity to implantation antigens CI-A, Pest Animal Control CRC |
$10,000 |
Past NHMRC Equipment Grants
| Date | Project/No. | Amount |
|---|---|---|
| 2010 | Infrared Fluorescence Imager for protein quantification CI-B with Russell D, Thompson JG et al. IDGNT9000031 |
$35,000 |
| 2010 | Radiometric and Reporter Gene Bioassay Facility CI-D with Gilchrist RB, Russell D, Thompson JG et al. IDGNT9000031 |
$40,000 |
| 2010 | Becton Dickinson FACSCanto II three laser Flow Cytometer CI-B with Ingman WV, Russell D, Moldenhauer LM et al. IDGNT9000031 |
$90,000 |
| 2008 | Applied Biosystems 7900HT low density array Taqman PCR platform CI-C with Russell D, Owens JA, Thompson JT, Somogyi A, et al. ID 580008 |
$70,000 |
| 2008 | PIXImus II DEXA XRay system for small animal analysis CI-E with Kennaway D, Owens JA, Norman RJ, Thompson JG, et al. ID 580008 |
$62,000 |
| 2007 | Genomelab GeXP Genetic analysis system CI-H with Kennaway D, Owens JA, Wittert GA, Hiendleder S, et al. ID520946 |
$65,000 |
| 2007 | SlidePath digital SlideServer software, Acer Altos R250 Server CI-H with Owens JA, Tilley WD, Norman RJ, Findlay D, et al. ID520946 |
$52,510 |
| 2006 | Ariol SL-50 for high throughput image analysis CI-I with Tilley WD, Owens JA, Norman RJ, Findlay D, et al. ID467207 |
$100,695 |
| 2005 | 2 x Applied Biosystems 7500 Real Time PCR Machine, CI-I with JA Owens, KL Gatford, JS Robinson, et al. ID264655 |
$97,000 |
| 2005 | Rodent blood pressure monitoring station, CI-H with L MacKenzie, DA Saint, J Ross, RJ Irvine et al. ID219354 |
$97,000 |
| 2004 | MC-Nikon 018C1A Confocal Microscope CI-B with Thompson JG ID264518 |
$21,100 |
| 2004 | Cobas Integra 400 plus Roche Clinical Chemistry Analyser CI-J with Owens JA, Gatford KL, Robinson JS, Schwartz J, et al ID264518 |
$40,000 |
| 2004 | Amersham Biosciences Typhoon #9410 Imaging System CI-D with Rogers RJ, Ivell RJ, Gibson MA, Saint DA, Russell DL ID264518 |
$117,500 |
| 2003 | ABI Prism 7000 Sequence Detection System CI-A with Rodgers AJ, Armstrong DT, Thompson JG, Norman RJ ID219354 |
$46,110 |
| 2003 | Agilent Nanoflow LC System for QTOF2 mass spectrometer CI-E with Findlay DM, McColl SR, Wallace JC, Tilley WD ID219354 |
$68,649 |
| 2001 | POLAR Star Galaxy (BMG) Fluorescent Microplate Reader CI-E with Fontaine FR, Bochner F, McMillen IC, Rodgers RJ etc. |
$69,257 |
| 2000 | Perkin Elmer 5990 real-time thermal cycler CI-C with JA Owens, IC McMillen, JS Robinson et al. |
$50,000 |
| 1995 | Sorvall RC5C Plus Superspeed Centrifuge CI-C with DT Kennaway, JA Owens, |
$20,000 |
Past State Competitive Scheme
| Date | Project/No. | Amount |
|---|---|---|
| 2008 | The role of host-derived TGFβ in the establishment of endometriotic lesions CI-C with Hull ML, Norman RJ Women’s and Children’s Hospital Research Grant |
$48,138 |
| 2007 | Tissue remodelling in endometriosis CI-B with Hull ML, Women’s and Children’s Hospital Research Grant |
$50,000 |
| 2005-2008 | SCreening fOr Pregnancy Endpoints; SA SCOPE CI-C with G Dekker, CT Roberts, J Robinson, R Norman, R Richards, R North Premier’s Science and Research Fund, Government of SA |
$2.37M |
| 2004-2005 | Towards improved IVF outcomes: An expression cloning approach to investigate the action of GM-CSF in pre-implantation development CI-B with D’Andrea RJ, Brown AL, Sadlon TJ, Roberts CT Women’s and Children’s Hospital Foundation, adelaide |
$44,480 |
| 2000 | Characterisation of a reproductive lesion in b2-glycoprotein1 null mice: a model for anti-phospholipid syndrome. CI-A with Krilis SA (University of NSW), WCH Foundation, Adelaide |
$28,402 |
Past Intramural Schemes – Project Grants
| Date | Project/No. | Amount |
|---|---|---|
| 2006-2007 | Physiological role of TGFβ in erectile function and dysfunction CI-C with Ingman WV, Musgrave IF - Faculty of Health Sciences – Small Grants Scheme |
$25,000 |
| 2005-2006 | Macrophage–regulating cytokines in mammary gland development and disease, CI-B with Ingman WV - Faculty of Health Sciences – Small Grants Scheme |
$17,000 |
| 2003-2004 | The influence of acupuncture on pregnancy rates for women undergoing embryo transfer: a randomised controlled trial CI-C, with Smith C, Norman RJ - Faculty of Health Science |
$8,800 |
| 2000-2002 |
Reproductive Medicine Fund Grant, University of Adelaide CI-A |
$50,000 |
| 2000 | The role of IL-10 in murine pregnancy CI-A with Ramsay AJ (University of Newcastle), ARC small grant |
$10,000 |
| 1999 | Semen exposure and pregnancy outcome in women CI-B with G Dekker, KP Tremellen, University of Adelaide (B3 Category) |
$25,000 |
| 1999 | The role of GM-CSF in early embryo development CI-A with RJ Norman, University of Adelaide (B1 Category) |
$10,000 |
| 1999 | Fertility and fecundity in IL-6 deficient mice CI-A with AJ Ramsay, ARC Small Grant |
$10,000 |
| 1998 | Immune deviation and pregnancy outcome CI-A, University of Adelaide (B3) |
$10,000 |
| 1998 | The role of chemokines in early murine pregnancy CI-A, ARC Small Grant |
$10,000 |
| 1995 | Seminal plasma proteins as determinants of pregnancy outcome CI-A with RF Seamark. The Florey Research Fund Faulding Grant 1995 |
$10,000 |
Past Intramural Schemes - Equipment Grants (Faculty of Heath Sciences, unless indicated otherwise)
| Date | Project/No. | Amount |
|---|---|---|
| 2008 | Applied Biosystems 7900HT low density array Taqman PCR platform CI-C with Russell D, Owens JA, Thompson JT, Somogyi A, et al. |
$20,000 |
| 2008 | PIXImus II DEXA XRay system for small animal analysis CI-E with Kennaway D, Owens JA, Norman RJ, Thompson JG, et al. |
$20,000 |
| 2007 | Genomelab GeXP Genetic analysis system CI-H with Kennaway D, Owens JA, Wittert GA, Hiendleder S, et al. |
$20,000 |
| 2007 | SlidePath digital SlideServer software, Acer Altos R250 Server CI-H with Owens JA, Tilley WD, Norman RJ, Findlay D, et al. |
$20,000 |
| 2006 | Ariol SL-50 for high throughput image analysis CI-I with Tilley WD, Owens JA, Norman RJ, Findlay D, et al. |
$25,000 |
| 2005 | Applied Biosystems 7500 Real Time PCR Machine CI-I with JA Owens, KL Gatford, JS Robinson, et al. O&G Strategic Research Development Grant |
$16,000 |
| 2005 | Two Applied Biosystems 7500 Real Time PCR Systems CI-B with Owens JA, Thompson JG, Nottle M, Kennaway D, et al. |
$15,000 |
| 2005 | Eppendorf Microfuge CI-D with DJ Kennaway, CT Roberts, JA Owens, R Rodgers, M Jasper, O&G Strategic Research Development Grant |
$4,350 |
| 2005 | Becton Dickinson FACSCanto 6-colour Flow Cytometer CI-A with Robker R, Ingman WV, O&G Strategic Research Development Grant |
$40,000 |
| 2004 | MC-Nikon 018C1A Confocal Miscroscope CI-B with Thompson JG |
$16,100 |
| 2004 | Cobas Integra 400 plus Roche Clinical Chemistry Analyser CI-J with Owens JA, Gatford KL, Robinson JS, Schwartz J, et al |
$2,852 |
| 2004 | Amersham Biosciences Typhoon #9410 Imaging System CI-D with Rogers RJ, Ivell RJ, Gibson MA, Saint DA, Russell DL |
$58,750 |
| 2003 | ABI Prism 7000 Sequence Detection System CI-A with Rodgers AJ, Armstrong DT, Thompson JG, Norman RJ |
$23,055 |
| 2003 | Agilent Nanoflow LC System for QTOF2 mass spectrometer CI-E with Findlay DM, McColl SR, Wallace JC, Tilley WD |
$34,324 |
| 2000 | Leading Edge Video Image Analysis System CI-A with CT Roberts Ramaciotti Foundations: project RA093/00 |
$9,770 |
| 1999 | Biorad ELISA plate reader CI-A with CT Roberts, Ramaciotti RAMA 99 |
$11,000 |
| 1998 | Detection and quantification of cytokine mRNAs during pregnancy CI-A with CT Roberts, Ramaciotti Foundations: project RAMA 98082 |
$10,974 |
| 1995 | Miltenyi Biotec 'MiniMACS' magnetic cell sorter CI-A with RJ Norman |
$4,880 |
| 1994 | Hybaid Omnigene Thermal Cycler CI-A, Co-operative Foundation Grant |
$10,000 |
Undergraduate teaching (at University of Adelaide unless otherwise indicated)
| Date | Course |
|---|---|
| 1995-2007, 2013 | Lecturer and examiner, Infection and Immunity II |
| 2002-2004, 2011 | Lecturer, Molecular and Cell Biology I |
| 2005-present | Lecturer, Comparative Reproductive Biology III |
| 1997-present | Lecturer and problem-based learning tutor, Human Reproductive Health II |
| 2000-present | Project Supervisor, Medical Research Project IV, University of Leiden, The Netherlands |
Other postgraduate teaching
| Date | Course |
|---|---|
| 1995-2003 | Tutor and Examiner, Experimental Methodology, Dept. Obstetrics and Gynaecology |
| 1995-2007 | Ad-hoc External Examiner, Depts. Microbiology and Immunology / Animal Sciences |
| 1995-present | Assessor, BSc (Hons) Research Projects, Dept. Obstetrics and Gynaecology |
PhD thesis examination
University of Melbourne (1996); University of Sydney (1998, 2005); University of NSW (2001); University of Newcastle (2001, 2003); Monash University (2006, 2007, 2008); The University of Auckland (2009, 2010); University of Cape Town, SOUTH AFRICA (2011); Indian Institute of Science Bangalore, INDIA (2011).
-
Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2025 Co-Supervisor Recurrent pregnancy loss Doctor of Philosophy Doctorate Full Time Miss Cristina Norzel Arriaran Scott 2024 Principal Supervisor Significance of impaired immune tolerance for infertility in men. Doctor of Philosophy Doctorate Full Time Ms Shreetha Ramasubramanian 2024 Principal Supervisor Paternal MHC disparity and maternal immune adaptation to pregnancy. Doctor of Philosophy Doctorate Full Time Miss Le Phuong Uyen Pham 2024 Co-Supervisor Innate phagocytosis from a basic feeding behaviour to a regulated defence action Doctor of Philosophy Doctorate Full Time Mr Wei Da Ho 2024 Co-Supervisor Delineating the relationship between metabolic and immune dysfunction that underpins recurrent pregnancy loss. Doctor of Philosophy Doctorate Full Time Dr Rashmi Baid 2023 Principal Supervisor Identity of seminal fluid antigens driving expansion of the female adaptive immune response after mating Doctor of Philosophy Doctorate Full Time Mr Ha Manh Tran 2021 Principal Supervisor Regulatory T cell contributions to maternal immune system dysfunction in preterm birth Doctor of Philosophy Doctorate Full Time Miss Jessie Rose Walker 2021 Co-Supervisor Immune cells in preeclampsia – a target for cardiovascular disease prevention? Doctor of Philosophy Doctorate Full Time Miss Evangeline Alice Ksenija Lovell 2020 Principal Supervisor New insight into spermatozoa selection for improving assisted reproductive technologies (ARTs) outcomes Doctor of Philosophy Doctorate Full Time Mrs Soraya Rasi Ghaemi 2019 Co-Supervisor Mechanisms of Action of Lipiodol in Women Undergoing Reproductive Therapy Doctor of Philosophy Doctorate Part Time Mr Faizz Fattah -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2022 - 2024 Principal Supervisor Peri-conception Contributions to the Origins of Autoimmunity Doctor of Philosophy Doctorate Full Time Miss Stacey Jasmin Savin 2020 - 2020 Co-Supervisor Management Options for Hydrosalpinx - Salpingostomy or IVF Doctor of Philosophy Doctorate Full Time APrf Oswald Petrucco 2017 - 2020 Principal Supervisor The Effect of Washed vs Unwashed Packed Red Blood Cell Transfusion on Immune Responses in the Extremely Preterm Newborn: A Randomised Trial Doctor of Philosophy Doctorate Full Time Miss Tara Marie Crawford 2017 - 2021 Principal Supervisor The role of macrophages in vascular adaptation to pregnancy in mice Doctor of Philosophy Doctorate Full Time Miss Holly Michelle Groome 2015 - 2020 Principal Supervisor Progesterone control of regulatory T cell abundance, phenotype and stability for pregnancy success Doctor of Philosophy Doctorate Full Time Ella Shana Green 2015 - 2019 Co-Supervisor The contribution of immune regulatory MicroRNAs in endometriosis Doctor of Philosophy Doctorate Full Time Miss Kavita Panir 2015 - 2020 Principal Supervisor Regulators of Seminal Fluid Signalling and their Impact on Gene Expression during the Peri-Implantation Period of Pregnancy Doctor of Philosophy Doctorate Full Time Dr Hon Yeung Chan 2013 - 2018 Principal Supervisor T Regulatory Cells in Early Pregnancy in Mice Doctor of Philosophy Doctorate Full Time Miss Bihong Zhang 2013 - 2017 Principal Supervisor Toll-Like Receptor 4 Signalling in Inflammation Pathways to Term and Preterm Delivery Doctor of Philosophy Doctorate Full Time Miss Hanan Hamimi Binti Wahid 2012 - 2015 Co-Supervisor Cytokine-macrophage Regulatory Network in Mammary Gland Development and Tumourigenesis Doctor of Philosophy Doctorate Full Time Miss Xuan Sun 2011 - 2014 Principal Supervisor The Effect of Macrophages on Fibroblast Activity and Lesion Development in Mouse Models of Endometriosis Doctor of Philosophy Doctorate Full Time Mr Zahied Zahied Johan 2011 - 2017 Co-Supervisor Effect of C1q Null Mutation on Mammary Gland Development and Breast Cancer Susceptibility Doctor of Philosophy Doctorate Full Time Miss Siti Mariam Noor Din 2009 - 2012 Principal Supervisor The Role of Macrophages in Early Pregnancy Success Doctor of Philosophy Doctorate Full Time Dr Alison Care 2009 - 2014 Principal Supervisor Cytokines and programming the pre-implantation embryo Doctor of Philosophy Doctorate Full Time Dr Loretta Chin 2009 - 2013 Principal Supervisor Circulating microRNAs in endometriosis Doctor of Philosophy Doctorate Full Time Dr Victoria Nisenblat 2008 - 2009 Co-Supervisor Characterisation of the Development and Hormonal Regulation of the Ovarian Lymphatic Vasculature Doctor of Philosophy Doctorate Full Time Prof Hannah Brown 2008 - 2010 Principal Supervisor Seminal Fluid and Cytokine Control of Regulatory T-Cells in Murine Pregnancy Doctor of Philosophy Doctorate Full Time Mr Leigh Guerin 2006 - 2008 Principal Supervisor Pathways of Paternal Antigen Presentation to Initiate Antigen-Specific Immune Responses in Pregnancy Doctor of Philosophy Doctorate Full Time Dr Lachlan Moldenhauer 2005 - 2008 Principal Supervisor Actions of Seminal Fluid Signalling Factors in the Female Reproductive Tract and on Pregnancy Outcome Doctor of Philosophy Doctorate Full Time Dr Danielle Glynn 2005 - 2009 Principal Supervisor The Impact of Exogenous TGF Beta 1 on Male Reproductive Function Doctor of Philosophy Doctorate Full Time Ms Leanne McGrath 2003 - 2006 Principal Supervisor The Physiological Significance of Insemination in Programming Pregnancy Outcome Doctor of Philosophy Doctorate Full Time Dr John Bromfield 2002 - 2005 Principal Supervisor Seminal Plasma Regulation of the Post-Coital Inflammatory Response in the Human Cervix Doctor of Philosophy Doctorate Full Time Dr David Sharkey 1999 - 2010 Principal Supervisor Seminal Plasma Cytokines as Determinants of Ovulation, Embryo Development and Pregnancy Success in the Pig Doctor of Philosophy Doctorate Full Time Dr Sean O'Leary 1998 - 2002 Principal Supervisor The effect of transforming growth factor beta1 null mutation on murine reproductive function Doctor of Philosophy Doctorate Full Time APrf Wendy Ingman -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2018 - 2018 Co-Supervisor Macrophage alterations in microRNA deficient mouse models of endometriosis The University of Adelaide Bachelor of Health and Medical Sciences (Honours) (First Class Honours Award) Honours Full Time Kavita Bikram Shah
-
Board Memberships
Date Role Board name Institution name Country 2024 - ongoing Member Eureka Award Judging Panel Australian Museum Australia 2020 - ongoing Advisory Board Member Scientific Advisory Committee Ramaciotti Foundations Australia 2019 - 2021 Board Member AAMRI Board Association of Australian Medical Research Institutes Australia 2015 - 2021 Member Maternal & Neonatal Health Community of Practise, SA Health South Australian Government Australia 2014 - 2017 Member Women's and Children's Hospital Research Institute The Womens and Childrens Hospital, Adelaide Australia 2014 - ongoing Member Channel 7 Children's Research Foundation - Australia 2013 - ongoing Advisory Board Member Advisory Board, Robinson Research Institute The University of Adelaide Australia 2008 - 2009 Advisory Board Member Board, Mater Medical Research Institute Mater Medical Research Institute Australia 2001 - 2010 Board Member Bio Innovation SA Bio Innovation SA Australia -
Committee Memberships
Date Role Committee Institution Country 2023 - ongoing Chair Selection Panel SC10 (Immunology), Australian Academy of Science Australian Academy of Science Australia 2021 - 2022 Member Selection Panel SC10 (Immunology), Australian Academy of Science Australian Academy of Science Australia 2020 - ongoing Member Ramaciotti Foundations Scientific Advisory Committee Ramaciotti Foundations Australia 2019 - 2021 Member SSR Awards Committee Society for the Study of Reproduction United States 2018 - 2019 Chair Selection Panel SC7 (Physiology, Neuroscience), Australian Academy of Science Australian Academy of Science Australia 2016 - 2018 Member Selection Panel SC7 (Physiology, Neuroscience), Australian Academy of Science Australian Academy of Science Australia 2013 - 2014 Chair Nominations Committee Society for the Study of Reproduction United States 2011 - ongoing Member Lloyd Cox Endowment Fund - - 2008 - ongoing Chair School Space Committee - Medical School Campus - - 2003 - 2006 Member Research Committee of the NHMRC (2003-2006) NHMRC Australia -
Memberships
Date Role Membership Country 2015 - ongoing Member Australian Academy of Health and Medical Sciences Australia 2013 - 2014 Representative International Union of Immunological Societies Germany 2011 - ongoing Member NHMRC Academy Australia 2010 - ongoing Member American Association of Immunologists United States 2006 - 2009 Treasurer Society for Reproductive Biology Australia 2005 - ongoing Member American Society for the Immunology of Reproduction United States 2003 - 2006 Member NHMRC Council Australia 1998 - ongoing Secretary International Society for the Immunology of Reproduction Japan 1995 - ongoing Member Society for the Study of Reproduction United States 1989 - ongoing Member Australasian Society for Immunology Australia 1988 - ongoing Member Society for Reproductive Biology Australia -
Community Engagement
Date Title Engagement Type Institution Country 2024 - ongoing ABC National Radio Sex is Weird "Sexy females fight back" Public Community Engagement ABC National Radio Australia 2016 - ongoing Festival of Ideas presentation "Resistance and Persistence" Public Community Engagement The Adelaide Festival of Ideas Australia 2016 - ongoing New Scientist article "Semen reshapes immune system to boost chances of pregnancy" Scientific Community Engagement New Scientist magazine United States 2014 - ongoing ABC Science article "Seminal fluid key to offspring health"" Public Community Engagement Australian Broadcasting Commission Australia 2013 - ongoing Louis Waller Lecture of VARTA, The Victorian Assisted Reproduction Treatment Authority “Parenting Begins Before Conception" Public Community Engagement The Victorian Assisted Reproduction Treatment Authority Australia 2012 - ongoing Healthy Development Adelaide public lecture "The male contribution to embryo implantation" Public Community Engagement Healthy Development Adelaide Australia 2011 - ongoing Research Tuesday public seminar of the University of Adelaide “The discriminating female – How the choosy female immune system exercises reproductive quality control” Public Community Engagement The University of Adelaide Australia 2004 - ongoing ABC Catalyst Feature "Sperm tolerance" Public Community Engagement ABC Catalyst Feature Australia 2002 - ongoing Nature commentary "Immunity's pregnant pause" Scientific Community Engagement Nature magazine United States 2002 - ongoing New Scientist article "Gentle Persuasion" Scientific Community Engagement New Scientist magazine United States -
Consulting/Advisories
Date Institution Department Organisation Type Country 2024 - ongoing Cooper Surgical P/L Origio A/S Infertility Products Health services and related United States 2023 - ongoing Australian Government, Advisor to Roundtable on Pregnancy Loss Department of Health Legislative and political Australia 2022 - ongoing Early Pregnancy Loss Coalition Advisory Board Advocacy Australia 2020 - ongoing Hudson Institute of Medical Research Executive Scientific research Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2018 - ongoing Board Member Immunology and Cell Biology Australiasian Society for Immunology Australia 2018 - 2020 Board Member Endocrinology US Society for Endocrinology United States 2017 - ongoing Board Member Clinical and Translational Immunology - - 2014 - ongoing Consulting Editor Journal of Clinical Investigation - United States 2009 - 2013 Editor-In-chief Journal of Reproductive Immunology Journal of Reproductive Immunology United States 2008 - ongoing Board Member Reproduction The Journal of the Society for Reproduction and Fertility United Kingdom 2007 - 2010 Board Member Biology of Reproduction The Society for the Study of Reproduction United States 2003 - ongoing Board Member Journal of Reproductive Immunology Journal of Reproductive Immunology United States -
Expert Witness
Date Case Institution Country 2023 - 2023 Turner v Bayer Australia Ltd Supreme Court of Victoria Australia -
Industry Partnerships
Date Engagement Type Partner Name 2024 - ongoing Consultant Cooper Surgical P/L 2019 - 2023 Consultant Ferring Pharmaceuticals P/L 2019 - 2022 Consultant Organon P/L 2018 - ongoing Research Contract Guerbet P/L 2018 - 2022 Research Contract Ferring Pharmaceuticals 2017 - 2021 Consultant MSD Australia 2005 - 2017 Consultant ORIGIO A/S, Denmark -
Offices Held
Date Office Name Institution Country 2024 - ongoing Member, NHMRC Embryo Research Licensing Committee National Health and Medical Research Council Australia 2024 - ongoing President-Elect Society for Reproductive Biology, Australia Australia 2021 - 2024 Member, NHMRC Embryo Research Licencing Committee National Health and Medical Research Council Australia 2019 - ongoing Council Member International Society for immunology of reproduction Japan 2017 - 2019 Secretary-General International Society of Reproductive Immunology Japan 2015 - 2016 Chair, Inflammation in Reproduction, Pregnancy and Development; a Satellite Conference of the International Congress in Immunology, International Society of Reproductive Immunology Australia 2015 - ongoing Associate Member, South Australian Health and Medical Research Institute SAHMRI - 2008 - 2010 Chair, XI International Congress of Reproductive Immunology International Society of Immunology of Reproduction Australia 1999 - 2003 Associate Scientist Pest Animal CRC, Canberra Australia 1999 - ongoing External Member Hanson Centre for Cancer Research Australia 1997 - 2003 Scientific Adviser Fertilitetscentrum AB, Göteborg Sweden
Connect With Me
External Profiles
