Shreetha Ramasubramanian

Shreetha Ramasubramanian

Higher Degree by Research Candidate

School of Biomedicine

Faculty of Health and Medical Sciences

My research investigates the significance of impaired immune tolerance for infertility in men and women. Immune tolerance is important for individual fertility status and might have an additive effect on conception outcomes as a couple.

Maternal T cells can recognise paternal antigens expressed by the embryo and a system to suppress this effector function is vital for successful pregnancy outcomes. The activity of regulatory T cells or Treg cells is essential for this immune modulation and homeostasis. The abundance of Treg cells might decline due to lifestyle or environmental factors and insufficient anti-inflammatory activity of Treg cells maybe a contributing factor to infertility or subfertility in men and women.

Clinically, male fertility status investigation is limited to semen analysis using WHO guidelines. However, meeting the WHO standards is not as assurance of fertility. While there is evidence supporting the association between seminal fluid and T cell parameters, specifically Treg cell population in peripheral blood of men, the correlation has not been fully understood. Our research aims to evaluate the seminal fluid and Treg cell parameters in men attending a reproductive medicine clinic for treatment of infertility and to correlate these findings to couple immune compatibility. 

  • Appointments

    Date Position Institution name
    2024 - 2024 Teaching Assistant University of Adelaide
    2024 - ongoing PhD Candidate University of Adelaide
    2023 - 2024 Research Assistant University of Adelaide
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2024 Award The School of Biological Sciences Prize in Master of Biotechnology (Biomedical) University of Adelaide Australia $500
  • Language Competencies

    Language Competency
    English Can read, write and speak
    Hindi Can read, write and understand spoken
    Tamil Can read, write and speak
  • Education

    Date Institution name Country Title
    2022 - 2023 University of Adelaide Australia Master of Biotechnology (Biomedical)(Advanced)
    2017 - 2021 Vellore Institute of Technology University India Bachelor of Technology, Biotechnology
  • Certifications

    Date Title Institution name Country
    2023 Global IQ Connect University of Adelaide Australia
    2023 Safe Environments for Children an Young People Department of Human Services, South Australia Australia
    2023 ANZCCART ComPass Animal Welfare Training University of Adelaide Australia
    2022 Career Access Mentoring Program University of Adelaide Australia
  • Research Interests

  • Committee Memberships

    Date Role Committee Institution Country
    2024 - ongoing Board Member HeSPA - Health Sciences Postgraduate Association University of Adelaide Australia
    2023 - ongoing Advisory Board Member UVAGAI - University of Adelaide Tamil Students Society University of Adelaide Australia
    2022 - 2023 Vice-President UAVAGI - University of Adelaide Tamil Students Society University of Adelaide Australia
  • Memberships

    Date Role Membership Country
    2024 - ongoing Member Society for Reproductive Biology Australia
    2024 - ongoing Member Australian and New Zealand Placental Research Association Australia
    2024 - ongoing Member Healthy Development Adelaide Australia

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