Mr Ha Tran
Higher Degree by Research Candidate
School of Pharmacy and Biomedical Sciences
College of Health
Ha Tran (he/him) is pursuing his PhD and holds a Bachelor of Science (Advanced) degree from the University of Adelaide, obtained in 2021. Born in Vietnam, he moved to Alice Springs (Mparntwe) in 2008 before heading to Adelaide in 2019 for his undergraduate studies in Immunology and Bioinformatics.Ha's research is centred around the study of mammalian reproduction and development, with a focus on the immune regulation of fertility and pregnancy by male seminal fluid factors. He leverages cutting-edge technologies such as flow cytometry, single-cell sequencing, and machine learning to advance the understanding of T cell activation by seminal fluid proteins, which will be vital for enhancing breeding efficiency and reducing wastage in endangered species conservation and agriculture.In his spare time, he enjoys making elaborate meals with produce grown in his suburban backyard. As an ex-Territorian, he thoroughly enjoys camping, 4WD, and anything related to the Outback.
PhD Research
Role of seminal fluid histocompatibility antigens in T cell priming after mating in mice.
At conception, seminal fluid introduces factors into the female reproductive tract that help her immune system accept the genetically different fetus. Key proteins in this fluid, known as major and minor histocompatibility antigens (MHC and MiHC), may affect immune tolerance and pregnancy by triggering maternal T cell responses. Our study explores how these seminal fluid antigens initiate a T cell response that supports successful pregnancy.
Other Projects
1. Role of paternal beta-defensin 22 in promoting maternal immune tolerance and receptivity to implantation in mice.
During mating, molecules in seminal plasma and sperm work with the female reproductive system to trigger an immune reaction that helps her body become ready for pregnancy. This research examines the role of DEFB22, a protein in mice that corresponds to human DEFB126, in how seminal fluid influences fertility and the ability to produce offspring.
| Language | Competency |
|---|---|
| Vietnamese | Can read, write, speak, understand spoken and peer review |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2019 - 2021 | University of Adelaide | Australia | Bachelor of Science (Advanced) |
| Year | Citation |
|---|---|
| 2023 | Tran, H., Chan, H. Y., Adelson, D. L., & Robertson, S. A. (2023). Seminal fluid histocompatibility antigens contribute to T cell priming after mating in mice. Poster session presented at the meeting of Society of Reproductive Biology. Brisbane. |
| 2022 | Chan, H. Y., Tran, H. M., Breen, J., Schjenken, J., & Robertson, S. (2022). The endometrial transcriptome transition preceding receptivity to embryo implantation in mice. Poster session presented at the meeting of Society of Reproduction. Christchurch, New Zealand. |
| 2022 | Chan, H. Y., Tran, H. M., Breen, J., Schjenken, J., & Robertson, S. (2022). The endometrial transcriptome transition preceding receptivity to embryo implantation in mice. Poster session presented at the meeting of Society of Reproduction. Christchurch, New Zealand. |
| Year | Citation |
|---|---|
| - | Chan, H. Y., Tran, H., Breen, J., Schjenken, J. E., & Robertson, S. (n.d.). <strong>The</strong> <strong>endometrial transcriptome transition preceding receptivity to embryo implantation in mice</strong>. DOI |
| Year | Citation |
|---|---|
| 2023 | Tran, H. (2023). The endometrial transcriptome transition preceding receptivity to embryo implantation in mice [Computer Software]. https://github.com/tranmanhha135/Mouse_endometrial_transcriptome_2023. |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2024 - ongoing | Member | Society for the Study of Reproduction (SSR) | United States |
| 2022 - ongoing | Member | The Society of Reproductive Biology (SRB) | Australia |
| 2022 - ongoing | Member | The Australian Bioinformatics and Computational Biology Society (ABACBS) | Australia |
| 2022 - ongoing | Member | Australian and New Zealand Society for Immunology (ASI) | Australia |
| 2021 - ongoing | Member | International Society for Computational Biology (ISCB) | United States |
| Date | Topic | Presented at | Institution | Country |
|---|---|---|---|---|
| 2023 - ongoing | Seminal fluid histocompatibility antigens contribute to T cell priming after mating in mice | - | The Society of Reproductive Biology | Australia |
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