School of Biomedicine
Faculty of Health and Medical Sciences
Hon Yeung (Dexter) Chan is a Postdoctoral Researcher in the Reproductive Immunology group at the Robinson Research Institute. His research aims to further the understanding and to define the significance of the male seminal fluid in the reproductive process, and the female response to signalling factors carried within the ejaculate. His research will help understand how both paternal and maternal factors contribute to normal reproductive processes and may ultimately, improve our understanding of the causes of infertility.
His current research interests include:
- the identification of the regulators of seminal fluid signalling that alter the female response to conception, such as signalling factors in the male ejaculate and receptors for these signalling moieties in the female reproductive tract
- the mechanisms by which semen contributes to gene regulation in the uterus during the peri-implantation phase of pregnancy critical for female receptivity for successful embryo implantation
Date Position Institution name 2020 Postdoctoral Researcher University of Adelaide
Language Competency Chinese (Cantonese) Can read, write, speak, understand spoken and peer review Chinese (Mandarin) Can read, speak and understand spoken English Can read, write, speak, understand spoken and peer review
Date Institution name Country Title 2015 - 2020 University of Adelaide Australia PhD in Medicine 2014 - 2014 University of Adelaide Australia Honours Degree of Bachelor of Health Sciences 2011 - 2013 University of Adelaide Australia Bachelor of Science (Biomedical Science)
Year Citation 2021 Schjenken, J. E., Sharkey, D. J., Green, E. S., Chan, H. Y., Matias, R. A., Moldenhauer, L. M., & Robertson, S. A. (2021). Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice. Communications Biology, 4(1), 14 pages.
2021 Schjenken, J. E., Moldenhauer, L. M., Sharkey, D. J., Chan, H. Y., Chin, P. Y., Fullston, T., . . . Robertson, S. A. (2021). High fat diet alters male seminal plasma composition to impair female immune adaptation for pregnancy in mice.. Endocrinology.
2020 Schjenken, J. E., Moldenhauer, L. M., Zhang, B., Care, A. S., Groome, H. M., Chan, H. -Y., . . . Robertson, S. A. (2020). MicroRNA miR-155 is required for expansion of regulatory T cells to mediate robust pregnancy tolerance in mice. Mucosal Immunology, 13(4), 609-625.
DOI Scopus8 WoS7 Europe PMC5
2020 McCarron, A., Cmielewski, P., Reyne, N., McIntyre, C., Finnie, J., Craig, F., . . . Donnelley, M. (2020). Phenotypic characterization and comparison of Phe508del and cystic fibrosis transmembrane conductance regulator (CFTR) knockout rat models of cystic fibrosis generated by CRISPR/Cas9 gene editing. The American Journal of Pathology, 190(5), 977-993.
DOI Scopus8 WoS8 Europe PMC7
2017 Robertson, S., Zhang, B., Chan, H., Sharkey, D., Barry, S., Fullston, T., & Schjenken, J. (2017). MicroRNA regulation of immune events at conception. Molecular Reproduction and Development, 84(9), 914-925.
DOI Scopus13 WoS12 Europe PMC10
2016 Schjenken, J. E., Zhang, B., Chan, H. Y., Sharkey, D. J., Fullston, T., & Robertson, S. A. (2016). miRNA Regulation of Immune Tolerance in Early Pregnancy. American Journal of Reproductive Immunology, 75(3), 272-280.
DOI Scopus24 WoS22 Europe PMC19
2014 Chua, K., Pietsch, M., Zhang, X., Hautmann, S., Chan, H., Bruning, J., . . . Abell, A. (2014). Macrocyclic protease inhibitors with reduced peptide character. Angewandte Chemie International Edition, 53(30), 7828-7831.
DOI Scopus19 WoS18 Europe PMC7
Year Citation 2020 Robertson, S. A., Schjenken, J. S., Moldenhauer, L. M., Zhang, B., Groome, H. M., Chan, H. Y., & Care, A. S. (2020). miR-155 Deficiency Impairs Pregnancy Tolerance and Predisposes to Inflammation-Induced Fetal Loss in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG.
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