Dr Hon Yeung Chan

ARC Grant-Funded Researcher (A)

School of Biomedicine

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

My Research
Career
Publications
Supervision
Contact

Hon Yeung (Dexter) Chan is a Postdoctoral Researcher in the Reproductive Immunology group at the Robinson Research Institute. His research aims to further the understanding and to define the significance of the male seminal fluid in the reproductive process, and the female response to signalling factors carried within the ejaculate. His research will help understand how both paternal and maternal factors contribute to normal reproductive processes and may ultimately, improve our understanding of the causes of infertility.

His current research interests include:

the identification of the regulators of seminal fluid signalling that alter the female response to conception, such as signalling factors in the male ejaculate and receptors for these signalling moieties in the female reproductive tract
the mechanisms by which semen contributes to gene regulation in the uterus during the peri-implantation phase of pregnancy critical for female receptivity for successful embryo implantation

Appointments

Date Position Institution name
2020 - ongoing Postdoctoral Researcher University of Adelaide

Date	Position	Institution name
2020 - ongoing	Postdoctoral Researcher	University of Adelaide

Language Competencies

Language	Competency
Chinese (Cantonese)	Can read, write, speak, understand spoken and peer review
Chinese (Mandarin)	Can read, speak and understand spoken
English	Can read, write, speak, understand spoken and peer review

Education

Date	Institution name	Country	Title
2015 - 2020	University of Adelaide	Australia	PhD in Medicine
2014 - 2014	University of Adelaide	Australia	Honours Degree of Bachelor of Health Sciences
2011 - 2013	University of Adelaide	Australia	Bachelor of Science (Biomedical Science)

Research Interests

Fertility and Conception Men's Health Pregnancy and Birth Fertility Immunology Obstetrics & Reproductive Medicine Reproduction Reproductive Biology

Journals

Year	Citation
2024	Green, E. S., Chan, H. Y., Frost, E., Griffiths, M., Hutchison, J., Martin, J. H., . . . Dunleavy, J. E. M. (2024). Recent advances in reproductive research in Australia and New Zealand: highlights from the Annual Meeting of the Society for Reproductive Biology, 2022. Reproduction, Fertility and Development, 36(4), 10 pages. DOI
2024	Chin, P. Y., Chan, H. Y., Kieffer, T. E. C., Prins, J. R., Russell, D. L., Davies, M. J., & Robertson, S. A. (2024). Clomiphene Citrate Administered in Periconception Phase Causes Fetal Loss and Developmental Impairment in Mice. Endocrinology (United States), 165(7), 15 pages. DOI Europe PMC1
2023	Chan, H. Y., Tran, H. M., Breen, J., Schjenken, J. E., & Robertson, S. A. (2023). The endometrial transcriptome transition preceding receptivity to embryo implantation in mice. BMC Genomics, 24(1), 1-16. DOI Scopus2 Europe PMC3
2021	Schjenken, J. E., Sharkey, D. J., Green, E. S., Chan, H. Y., Matias, R. A., Moldenhauer, L. M., & Robertson, S. A. (2021). Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice. Communications Biology, 4(1), 1-14. DOI Scopus27 WoS20 Europe PMC20
2021	Schjenken, J. E., Moldenhauer, L. M., Sharkey, D. J., Chan, H. Y., Chin, P. Y., Fullston, T., . . . Robertson, S. A. (2021). High fat diet alters male seminal plasma composition to impair female immune adaptation for pregnancy in mice. Endocrinology, 162(10), 1-20. DOI Scopus18 WoS11 Europe PMC11
2021	Chan, H. Y., Moldenhauer, L. M., Groome, H. M., Schjenken, J. E., & Robertson, S. A. (2021). Toll-like receptor-4 null mutation causes fetal loss and fetal growth restriction associated with impaired maternal immune tolerance in mice.. Scientific reports, 11(1), 1-17. DOI Scopus16 WoS12 Europe PMC9
2020	Schjenken, J. E., Moldenhauer, L. M., Zhang, B., Care, A. S., Groome, H. M., Chan, H. Y., . . . Robertson, S. A. (2020). MicroRNA miR-155 is required for expansion of regulatory T cells to mediate robust pregnancy tolerance in mice. Mucosal Immunology, 13(4), 609-625. DOI Scopus33 WoS28 Europe PMC20
2020	McCarron, A., Cmielewski, P., Reyne, N., McIntyre, C., Finnie, J., Craig, F., . . . Donnelley, M. (2020). Phenotypic characterization and comparison of Phe508del and cystic fibrosis transmembrane conductance regulator (CFTR) knockout rat models of cystic fibrosis generated by CRISPR/Cas9 gene editing. The American Journal of Pathology, 190(5), 977-993. DOI Scopus29 WoS20 Europe PMC23
2017	Robertson, S., Zhang, B., Chan, H., Sharkey, D., Barry, S., Fullston, T., & Schjenken, J. (2017). MicroRNA regulation of immune events at conception. Molecular Reproduction and Development, 84(9), 914-925. DOI Scopus20 WoS17 Europe PMC15
2016	Schjenken, J. E., Zhang, B., Chan, H. Y., Sharkey, D. J., Fullston, T., & Robertson, S. A. (2016). miRNA Regulation of Immune Tolerance in Early Pregnancy. American Journal of Reproductive Immunology, 75(3), 272-280. DOI Scopus44 WoS35 Europe PMC27
2014	Chua, K., Pietsch, M., Zhang, X., Hautmann, S., Chan, H., Bruning, J., . . . Abell, A. (2014). Macrocyclic protease inhibitors with reduced peptide character. Angewandte Chemie International Edition, 53(30), 7828-7831. DOI Scopus23 WoS20 Europe PMC8

Conference Papers

Year	Citation
2019	Parsons, D., Cmielewski, P., Mccarron, A., Mcintyre, C., Craig, F., Finnie, J., . . . Donnelley, M. (2019). Update on the Australian cystic fibrosis rat colony. In Respirology Vol. 24 (pp. 136). Broadbeach, Qld.: Wiley.

Conference Items

Year	Citation
2020	Robertson, S. A., Schjenken, J. S., Moldenhauer, L. M., Zhang, B., Groome, H. M., Chan, H. Y., & Care, A. S. (2020). miR-155 Deficiency Impairs Pregnancy Tolerance and Predisposes to Inflammation-Induced Fetal Loss in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG.

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2024	Co-Supervisor	Paternal MHC disparity and maternal immune adaptation to pregnancy.	Doctor of Philosophy	Doctorate	Full Time	Miss Le Phuong Uyen Pham
2023	Co-Supervisor	Identity of seminal fluid antigens driving expansion of the female adaptive immune response after mating	Doctor of Philosophy	Doctorate	Full Time	Mr Ha Manh Tran

Position: ARC Grant-Funded Researcher (A)
Phone: 83137729
Email: honyeung.chan@adelaide.edu.au
Campus: North Terrace
Building: Adelaide Health and Medical Sciences, floor 6
Org Unit: Medical Sciences

Dr Hon Yeung Chan

Appointments

Language Competencies

Education

Research Interests

Journals

Conference Papers

Conference Items

Current Higher Degree by Research Supervision (University of Adelaide)

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