Michael Horowitz

Professor Michael Horowitz

Professor of Medicine & Head Endocrine Unit

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Professor Michael Horowitz was appointed to a Personal Chair at the University of Adelaide in 1995 and has been the Director of the Endocrine and Metabolic Unit at the Royal Adelaide Hospital since 1997. His research activities are almost exclusively clinically based and relate primarily to gastrointestinal motor, sensory, and hormonal function, particularly in the context of diabetes mellitus, appetite regulation, critical illness and aging.

Professor Horowitz leads the National Health and Medical Research Council (NHMRC) Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health (2012-17). He is a co-author of 604 peer-reviewed papers and 40 book chapters.

He has been the recipient of a number of awards, including the Elder Prize for Scholarship at the University of Adelaide in 1995, the Distinguished Research Prize of the Gastroenterological Society of Australia (1999), the Eric Susman Prize of the Royal Australasian College of Physicians (2000), the Kellion Award of the Australian Diabetes Society (2009), a Masters Award for Sustained Achievement in Digestive Sciences from the American Gastroenterological Association (2010), An inaugural Fellow to the Australasian Academy of Health and Medical Sciences (2014), and the Royal Australasian College of Physicians 75th Anniversary Award (2014).

Research

My major research interests are in the two unrelated areas of gastrointestinal motor function and metabolic bone disease.  In both instances this research is being performed on a collaborative basis and has attracted international recognition.  The high level of scholarship and my pivotal role in both of these research programmes is evidenced by: (i) 212 papers in international, peer-reviewed journals and 22 book chapters.  – The majority of these papers have been published in high impact journals such as Gastroenterology, Gut, the American Journal of Physiology, Diabetologia, the American Journal of Clinical Nutrition and the British Medical Journal and they were cited in the scientific literature 311 times in 1993 and 380 times in 1994;  (ii) considerable success in attracting funding from competitive sources.  I have been the recipient of a total of approximately $1,978,000 from external peer-reviewed granting bodies since 1994 including 11 project grants, each of three years duration, provided by the National Health and Medical Research Council of Australia and grants from the Dutch government and the US Department of Health and Human Services;  (iii) the ongoing involvement of established overseas researchers of the highest calibre;  (iv) multiple invitations to participate in both national and international meetings, and;  (v) the ability to attract both Australian and overseas research fellows (the latter usually provide their own funding).

Grants and Funding
2009-11 Project title: Effects of the fatty acid, lauric acid, on energy intake and gut motor and hormonal function in health and obesity National Health and Medical Research Council Project Grant Feinle-Bisset C, Clifton P, Horowitz M, Jones K, Wittert G Value: $714,000

2009-11

 Project title: Gastrointestinal function and appetite in obesity – acute and longer-term effects of changes in energy intake National Health and Medical Research Council Project Grant Feinle-Bisset C, Horowitz M, Clifton P, Value: Rades T, Jones K, Rayner C $714,000
2009 Project title: Measurement of arterial stiffness in diabetes Rebecca Cooper Research Foundation Horowitz M, Rayner C, Clifton P, Jones K, Feinle-Bisset C, Wittert G Value: $20,000
2009 Project title: Involvement of interstitial cells of Cajal (ICC) in the gastric dysmotility associated with acute changes in extracellular glucose concentration Royal Adelaide Hospital Research Project Grant Beckett E, Rayner C, Horowitz M, Game P, Spencer N Value: $20,000
2010-12      Project title: The effects of testosterone and a nutritional supplement on hospital admissions in under-nourished older people National Health and Medical Research Council Project Grant Chapman I, Visvanathan R, Naganathan V, Hunter P, Karnon J, Horowitz M, Lange K, Cameron I Value: $1,018,438
2010-12     Project title: Gastric, small intestinal and cardiovascular mechanisms in postprandial hypotension National Health and Medical Research Council Project Grant Jones K, Gentilcore D, Visvanathan R, Chapman I, Rayner C, Horowitz M. Value: $676,500
2010-12    Project title: Upper gastrointestinal function and glycaemic control in diabetes mellitus National Health and Medical Research Council Project Grant        Rayner C, Horowitz M, Jones K, Feinle-Bisset C Value: $753,500
2010  Project title: Measurement of superior mesenteric artery blood flow in patients with diabetes with and without postprandial hypotension Rebecca Cooper Medical Research Foundation Ltd Horowitz M, Jones KL, Gentilcore D, Rayner C Value: $22,000
2011 Project title: Assessment of splanchnic blood flow in humans Hanson Institute, Royal Adelaide Hospital Equipment Grant Jones KL, Gentilcore D, Visvanathan R, Chapman IM, Rayner CK, Deane A, Horowitz M Value: $65,000
2011 Project title: Studies in Nutritional Physiology and Related Diseases National Health and Medical Research Council Equipment Grant Wittert G, Horowitz M, Chapman I, Rayner C, Feinle-Bisset C, Jones KL, Heilbronn L, Beckett E. Value: $25,000
2011     Project title: Sweet taste receptors and critical illness Intensive Care Foundation Project Grant Deane A, Young R, Chapman M, O’Connor S, Rayner C, Horowitz M. Value: $45,000
2011  Project title: Measurement of glucose in blood or plasma Rebecca Cooper Medical Research Foundation Ltd Horowitz M, Rayner C, Jones K, Deane A Value: $22,000
2012    Project title: Optimising nutrient delivery and absorption in critically ill patients National Health and Medical Research Council Project Grant Chapman M, Nguyen N, Horowitz M, Rayner C, Jones K, Deane A. Value: $542,500
2012-2017  Project title: Translating Nutritional Science to Good Health National Health and Medical Research Council CRE Grant Horowitz M, Wittert G, Clifton P, Rayner C, Chapman I, Feinle-Bisset C, Jones K, Noakes M, Chapman M, Nguyen N Value: $2,500,000
2013     Project title: The Augmented versus Routine approach to giving energy trial (TARGET) in intensive care: a feasibility study) Australian and New Zealand College of Anaesthetists Research Grant Chapman M, Davies A, Deane A, Horowitz M, Moran J, O’Connor S, Peake S, Ridley E, Williams P Value: $34,300
2014-16     Project title: Modulating gastrointestinal function for control of diabetes National Health and Medical Research Council Project Grant Rayner CK, Horowitz M, Jones KL Value: $857,562
2014-16      Project title: Protein "preloads" to improve postprandial glycaemia in type 2 diabetes National Health and Medical Research Council Project Grant Rayner CK, Clifton PM, Horowitz M, Jones KL Value: $603,447
2014    Project title: Gallbladder motility in critical illness. Intensive Care Foundation Trainee Project Grant. Plummer MP, Deane AM, Chapman MJ, Horowitz M, Jones KL Value: $5,000
2014    Project title: The role of exanatide in post prandial glycaemia in Cystic fibrosis.  Channel 7 Research Foundation Couper J, Horowitz M, Rayner C Value: $72,000
2015-19      Project title: The Augmented versus Routine approach to Giving Energy Trial (TARGET). National Health and Medical Research Council Project Grant Chapman M, Peake S, Bellomo R, Horowitz M, Davies A, Deane, A. Value: $3,847,350
2015-17   Project title: Why do sweetened drinks link to type 2 diabetes? National Health and Medical Research Council Project Grant Young R, Rayner CK, Horowitz M. Value: $853,134
2015-18    Project title: Effects of dietary amino and fatty acids on energy intake and glycaemia - implications for novel approaches to the management of obesity and type 2 diabetes. National Health and Medical Research Council Project Grant Feinle-Bisset C, Horowitz M, Clifton P, Rayner C. Value: $715,493
2015     Project title: Gastric emptying, incretin hormones and glycaemia in non-diabetic Indigenous Australians – implications for the pathogenesis of type 2 diabetes. Royal Adelaide Hospital Research Project Grant Marathe C, Rayner CK, Horowitz M, Jones K. Value: $49,887
2015    Project title: Dietary protein digestion and absorption kinetics and subsequent postprandial muscle protein accretion in healthy young and older people. Royal Adelaide Hospital Research Project Grant Soenen S, van Loon L, Chapman I, Horowitz M. Value: $49,920
2016  Project title: Acute effects of oral nutrients on appetite and energy intake, gastric emptying and gut hormones in undernourished, obese and healthy older individuals. Royal Adelaide Hospital Research Project Grant Soenen S, Chapman I, Horowitz M. Value: 49,980
2016 Project title: Does instestinal bitter taste sensing modulate gastrointestinal motility and hormone secretion to reduce glycaemia and energy intake in humans? Royal Adelaide Hospital Research Project Grant Wu T, Rayner C, Horowitz M Value: $49,258
2016  Project title: A longitudinal study: does rapid gastric emptying increase the risk of type 2 diabetes? Royale Adelaide Hospital Research Project Grant Phillips L, Horowtz M, Rayner C, Jones K Value: $50,113
2016     Project title: Glycaemia in the critically ill – dysglycaemia as a predictor for incident type 2 diabetes and the effect of pre-existing type 2 diabetes on outcomes in survivors of critical illness. Diabetes Australia Research Trust Phillips LK, Horowitz M, Shaw JE, Deane AM and Plummer MP Value: $59,915
2016   Project title: Survivors of ICU with type 2 diabetes and the effect of shared care follow up clinics: The SWEET-AS feasibility study Intensive Care Foundation Ali Abdelhamid Y, Phillips L, Horowitz M and Deane AM Value: $35,000
Teaching activities

During all stages of my postgraduate career I have made major contributions and enjoyed both undergraduate and postgraduate teaching.  My involvement in postgraduate teaching on both a national and international basis is increasingly sought and I have consistently received excellent ratings for my teaching from both medical students and physician trainees.  Major initiatives include:

  1. International training in gastrointestinal motility
  2. Establishment of research project in the medical curriculum
  3. Contributions to professional literature and editorial boards
  4. Royal Adelaide Hospital Research Forum

In addition to those stated my current activities in relation to teaching include:

(i)         Postgraduate

(a)  Tutorials in general medicine and endocrinology to trainees undertaking the Part I examination for the Fellowship of the Royal Australasian College of Physicians (about 2 hours/week);  (b) invited lectures at local, national and international meetings (including lectures to interns and regular presentations at medical grand rounds at the Royal Adelaide Hospital) (about 3 hours each week);  (c) supervision of higher degree students; and (d)  supervision of postdoctoral research fellows.

 

(ii)         Undergraduate

Tutorials (mainly bed-side teaching) and lectures in general medicine and endocrinology (metabolic bone disease, pituitary function, diabetes, gastrointestinal disorders) to 3rd, 4th, 5th and 6th year medical students (about 8 hours/week).  This includes weekly tutorials (about 3 hours) to 4th year medical students during their attachment to the Professorial Medical Unit.  The Departmental student assessments of these tutorials has been extremely favourable;  (b)  examination of 4th, 5th and 6th year medical students.   I have had a major involvement in the 4th and 6th year medicine examinations and organised the clinical component of the 4th year examination at the Royal Adelaide Hospital on a number of occasions.

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  • Current Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2018 Co-Supervisor Effects of Lauric Acid, Alone or with Other Nutrients, on Energy Intake and Glycaemic Control Doctor of Philosophy Doctorate Full Time Ms Maryam Hajishafiee
    2018 Co-Supervisor Blood Glucose Management in Critically ill Patients with Pre-Existing Type-2 Diabetes Doctor of Philosophy Doctorate Full Time Mr Alexis Paul Poole
    2018 Co-Supervisor The effects of lauric acid and other dietary components on appetite, energy intake and blood glucose in lean and obese subjects Doctor of Philosophy Doctorate Full Time Mr Peyman Rezaie
    2017 Co-Supervisor Effects of the branded-chain amino acid, Valine, alone and in combination with other nutrients or the bitter substance, Quinine, on energy intake and blood glucose in healthy obese subjects Doctor of Philosophy Doctorate Full Time Ms Rachel Anne Elovaris
    2016 Co-Supervisor Mechanisms and management of postprandial hypotension Doctor of Philosophy Doctorate Full Time Mr Hung Thai Pham
    2015 Co-Supervisor Long-Term Outcome in Survivors of Critical Illness and Interaction with Glucose Metabolism Doctor of Philosophy Doctorate Full Time Dr Yasmine Ali Abdelhamid
    2015 Co-Supervisor Regulation of Energy Intake and Blood Glucose by Dietary Nutrients - Implications of Novel Therapeutic Approaches to Obesity and Type-2 Diabetes Doctor of Philosophy Doctorate Part Time Mrs Christina McVeay

  • Past Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2017 - 2019 Co-Supervisor Supporting the Journey of Pregnancy for Women with Type 1 Diabetes Doctor of Philosophy Doctorate Full Time Ms Helen Margret Edwards
    2015 - 2018 Co-Supervisor A Novel Nutritional Approach to the Management of Type 2 Diabetes: Effects of Nutritional Preloads on Postprandial Blood Glucose and Gastric Emptying in Type 2 Diabetes Mellitus Doctor of Philosophy Doctorate Full Time Dr Linda Ernestine Watson
    2014 - 2018 Co-Supervisor Hyperglycaemia in the Critically Ill Patient - Ideal Treatment and Impact of the Condition Doctor of Philosophy Doctorate Full Time Dr Palash Kar
    2014 - 2017 Co-Supervisor Corticosteroid-Binding Globulin – a Targeted Delivery System for Cortisol. Physiology and Responses to Acute and Chronic Inflammation Doctor of Philosophy Doctorate Full Time Dr Marni Anne Nenke
    2014 - 2018 Co-Supervisor Gastrointestinal Mechanisms in the 'Anorexia of Ageing' - Effects of Dietary Protein Doctor of Philosophy Doctorate Full Time Ms Caroline Gerda Thea Giezenaar
    2014 - 2017 Co-Supervisor Regulation of Energy Intake and Blood Glucose by Dietary Nutrients - Implications for Novel Therapeutic Approaches to Obesity and Type 2 Diabetes Doctor of Philosophy Doctorate Full Time Miss Sina Stefanie Ullrich
    2013 - 2016 Co-Supervisor Glycaemia and upper gastrointestinal function in health and critical illness Doctor of Philosophy Doctorate Full Time Dr Mark Plummer
    2013 - 2016 Co-Supervisor Gastrointestinal Mediation of Glucose Homeostasis and Postprandial Cardiovascular Risk Doctor of Philosophy Doctorate Full Time Dr Sony Thazhath
    2012 - 2016 Principal Supervisor Relationships of Gastric Emptying with Glycaemia. Insulin Secretion and the Incretin Effect in Health and Type 2 Diabetes Doctor of Philosophy Doctorate Part Time Dr Chinmay Marathe
    2011 - 2016 Co-Supervisor Gastric and Small Intestinal Determinants of Postprandial Blood Pressure and Glycaemia Doctor of Philosophy Doctorate Full Time Mr Laurence Trahair
    2010 - 2012 Principal Supervisor Gastric Motor Function in Health and Diabetes - Implications for Incretin Hormone Release and Postprandial Blood Glucose Regulation Master of Philosophy (Medical Science) Master Full Time Dr Jessica Lee Sing Chang
    2009 - 2013 Co-Supervisor Gastrointestinal motor and sensory function and hormone secretion - implications for postprandial blood glucose regulation in type 2 diabetes mellitus Doctor of Philosophy Doctorate Full Time Dr Tongzhi Wu
    2009 - 2017 Co-Supervisor Studies on the Relationship between Dietary Calcium and Bone Mineral Homeostasis in Post-menopausal Women Doctor of Philosophy Doctorate Full Time Dr Sunethra Devika Chin Thomas
    2007 - 2014 Co-Supervisor LACK OF DEMONSTRABLE HARMFUL EFFECT OF HIGHER PROTEIN WEIGHT LOSS DIETS ON BONE HEALTH AND NEPHROPATHY IN TYPE 2 DIABETES Doctor of Philosophy Doctorate Part Time Dr David Jesudason
    2007 - 2012 Co-Supervisor Glucose Metabolism in the Critically Ill Doctor of Philosophy Doctorate Full Time Dr Adam Deane
    2007 - 2011 Co-Supervisor The role of gastric and small intestinal mechanisms in postprandial hypotension Doctor of Philosophy Doctorate Full Time Ms Lora Vanis
    2006 - 2009 Co-Supervisor Evaluation of Appetite Regulation in Lean and Obese Individuals Doctor of Philosophy Doctorate Full Time Miss Ixchel Brennan
    2006 - 2010 Co-Supervisor Gastrointestinal motor function and glycaemic control in diabetes Doctor of Philosophy Doctorate Full Time Mrs Jing Ma
    2006 - 2010 Co-Supervisor Gastric and Small Intestinal Motor Function in Health and Disease - Implications for Glucose Absorption, Incretin Hormone Release, and Postprandial Blood Glucose Regulation Doctor of Philosophy Doctorate Full Time Mr Paul Kuo
    2005 - 2008 Co-Supervisor Investigations into the Gastrointestinal Control of Appetite and Nutritional Frailty Doctor of Philosophy Doctorate Full Time Dr Kamilia Tai
    2004 - 2008 Co-Supervisor The Role of the Free Fatty Acid, Lauric Acid, in Appetite Regulation and its Potential as an Appetite-Suppressant Doctor of Philosophy Doctorate Full Time Miss Kate Lauren Feltrin
    2003 - 2008 Co-Supervisor Factors Involved in the Regulation of Gastrointestinal Motility, Hormone Release, Symptoms and Energy Intake in Health and Patients with Functional Dyspepsia Doctor of Philosophy Doctorate Full Time Ms Amelia Nicole Pilichiewicz
    2003 - 2007 Principal Supervisor Gastrointestinal Motility and Glycaemic Control in Diabetes Doctor of Philosophy Doctorate Full Time Ms Reawika Chaikomin
    2003 - 2007 Co-Supervisor Role of the Gastrointestinal Tract in Postprandial Blood Pressure Regulation Doctor of Philosophy Doctorate Full Time Dr Diana Piscitelli
    2003 - 2007 Co-Supervisor Investigations into the Gastrointestinal Factors Involved in the Regulation of Appetite and Energy Intake Doctor of Philosophy Doctorate Full Time Dr Tanya Little
    2003 - 2005 Co-Supervisor Nutritional Frailty: Prevalence, Screening and Management Doctor of Philosophy Doctorate Full Time Prof Renuka Visvanathan
    2003 - 2009 Co-Supervisor Studies of Gastric Motility in Health and Diabetes Doctor of Philosophy Doctorate Part Time Ms Julie Eva Stevens
    2001 - 2005 Co-Supervisor Appetite, food intake and ageing: The role of the gut Doctor of Philosophy Doctorate Full Time Dr Barbara Parker
    1999 - 2008 Co-Supervisor Gastro-Duodenal Motility and Nutrition in the Critically Ill Doctor of Philosophy Doctorate Part Time Prof Marianne Chapman
    1995 - 2006 Principal Supervisor Bone Loss in Men and Women: Role of Calcium and Hormones Doctor of Philosophy Doctorate Full Time Dr Franca Scopacasa
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  • Committee Memberships
    Date Role Committee Institution Country
    2013 - ongoing Member National Health and Medical Research Council Assigners Academy — —
    2009 - ongoing Chair Research Advisory Committee Royal Australasian College of Physicians —

  • Memberships
    Date Role Membership Country
    2015 - ongoing Member Australian Academy of Health and Medical Sciences Australia
    2008 - ongoing Member Endocrine Society of Australia Australia
  • Position: Professor of Medicine & Head Endocrine Unit
  • Phone: 70742812
  • Email: michael.horowitz@adelaide.edu.au
  • Fax: 8223 3870
  • Campus: Royal Adelaide Hospital
  • Building: RAH - Eleanor Harrald, floor 8
  • Room: Endocrine and Metabolic Unit
  • Org Unit: Medical Specialties
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