Mark Plummer
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Dr Plummer has recently been appointed as the Head of Research and Innovation, Intensive Care Unit, Royal Adelaide Hospital. His research interests include stress hyperglycaemia, sepsis and neurocritical care. He is a current The Hospital Research Foundation Group Early Career Fellow and has received competitive grant funding from the NHMRC, Diabetes Australia and Intensive Care Foundation
Dr Plummer graduated from The University of Adelaide Medical School in 2008 as dux of his year (Keith Sheridan Prize). During his specialist training he was the recipient of prestigious national awards, for both the Australian and New Zealand College of Anaesthetists primary exam (Renton Medal, 2012) and the College of Intensive Care Medicine fellowship exam (Don Harrison Medal, 2019). In 2016 he completed a clinical research-based PhD through the Discipline of Acute Care Medicine at the University of Adelaide and was awarded a Dean’s Commendation for Doctoral Thesis Excellence. During his PhD candidacy he won numerous highly competitive national research awards including the Australian Diabetes Society President’s Award, the Australian and New Zealand Intensive Care Society Matt Spence Medal and the College of Intensive Care Medicine Felicity Hawker Medal. He then undertook post-doctoral research and advanced training in neurointensive care at Addenbrooke’s Hospital in Cambridge (UK), renowned as the international centre of excellence in neurointensive care training and research. He returned to Australia in 2018 to complete training in intensive care medicine and take up an honorary title as Senior Lecturer with the Department of Critical Care at the University of Melbourne. In 2020 he commenced employment as a consultant intensivist at the Royal Melbourne Hospital where he sat on the executive of the Royal Melbourne Intensive Care Research Unit.
Dr Plummer has established himself as an emerging international leader in critical care research. He is among the top 30 researchers in the world in the field of hyperglycaemia (expertscape.com) and is ranked in the top 1% for both diabetes and critical care. His high-impact research to date includes (i) defining the prevalence of stress hyperglycaemia in critical illness, (ii) identifying stress hyperglycaemia as a precursor for subsequent diabetes and (iii) characterising severe COVID-19 and its impact on the Australian healthcare system. He holds leadership positions on the Australian and New Zealand Intensive Care Society (ANZICS) ASM Committee, the ANZICS SPRINT-SARI COVID-19 management committee and the ANZICS/College of Intensive Care Medicine Global Health Special Interest Group. He has supervised two University of Melbourne MD Research Projects and two Honours students.
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Appointments
Date Position Institution name 2021 - ongoing Honorary Senior Lecturer University of Adelaide 2021 - ongoing Head of Research and Innovation Royal Adelaide Hospital 2020 - 2021 Intensive Care Specialist Royal Melbourne Hospital 2019 - ongoing Honorary Senior Lecturer University of Melbourne 2018 - 2019 Senior Registrar Royal Melbourne Hospital 2017 - 2017 Senior Fellow Royal Free Hospital 2016 - 2016 Senior Fellow Addenbrooke's Hospital 2010 - 2012 Registrar Royal Adelaide Hospital -
Awards and Achievements
Date Type Title Institution Name Country Amount 2022 Research Award Florey Medical Research Foundation Prize University of Adelaide Australia - 2019 Award CICM Professor G.A. (Don) Harrison Medal College of Intensive Care Medicine Australia - 2018 Research Award CICM Felicity Hawker Medal College of Intensive Care Medicine Australia - 2016 Research Award Harold Youngman Medal East Anglia Association of Anaesthetists United Kingdom - 2016 Research Award Dean's Commendation for Doctoral Thesis Excellence University of Adelaide Australia - 2014 Research Award ANZICS Tub Worthley Travelling Scholarship Australia and New Zealand Intensive Care Society Australia - 2014 Award Matt Spence Medal College of Intensive Care Medicine Australia - 2014 Scholarship NHMRC Post-graduate scholarship NHMRC Australia - 2013 Research Award Australian Diabetes Society President's Award Australian Diabetes Society Australia - 2013 Scholarship University of Adelaide Dawes Scholarship University of Adelaide Australia - 2013 Research Award Royal Adelaide Hospital NIMMO prize Royal Adelaide Hospital Australia - 2012 Award Renton Medal Australia and New Zealand College of Anaesthetists Australia - 2008 Award Keith Sheridan Prize University of Adelaide Australia - -
Education
Date Institution name Country Title 2013 - 2016 University of Adelaide Australia PhD 2003 - 2008 University of Adelaide Australia MBBS -
Postgraduate Training
Date Title Institution Country 2019 Fellow College of Intensive Care Medicine Australia -
Research Interests
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Journals
Year Citation 2024 Page, K., Viner Smith, E., Plummer, M. P., Ridley, E. J., Burfield, K., & Chapple, L. -A. S. (2024). Nutrition practices in critically ill adults receiving noninvasive ventilation: A quantitative survey of Australian and New Zealand intensive care clinicians. Australian Critical Care, 37(1), 43-50.
Scopus22024 van Zuylen, M. L., Siegelaar, S. E., Plummer, M. P., Deane, A. M., Hermanides, J., & Hulst, A. H. (2024). Perioperative management of long-acting glucagon-like peptide-1 (GLP-1) receptor agonists: concerns for delayed gastric emptying and pulmonary aspiration. British Journal of Anaesthesia, 132(4), 644-648.
Scopus14 Europe PMC42024 Karamesinis, A. D., Neto, A. S., Shi, J., Fletcher, C., Hinton, J., Xing, Z., . . . Perry, L. A. (2024). Sex Differences in Opioid Administration After Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia, 38(3), 701-708.
Scopus12024 Jeffcote, T., Battistuzzo, C. R., Plummer, M. P., McNamara, R., Anstey, J., Bellapart, J., . . . Udy, A. (2024). PRECISION-TBI: a study protocol for a vanguard prospective cohort study to enhance understanding and management of moderate to severe traumatic brain injury in Australia. BMJ Open, 14(2), 7 pages.
2024 Gribnau, A., van Zuylen, M. L., Coles, J. P., Plummer, M. P., Hermanns, H., & Hermanides, J. (2024). Cerebral Glucose Metabolism following TBI: Changes in Plasma Glucose, Glucose Transport and Alternative Pathways of Glycolysis—A Translational Narrative Review. International Journal of Molecular Sciences, 25(5), 2513.
Scopus1 Europe PMC12024 Hastak, P., Cromer, D., Malycha, J., Andersen, C. R., Raith, E., Davenport, M. P., . . . Sasson, S. C. (2024). Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia. Scientific Reports, 14(1), 10 pages.
2024 May, C. N., Ow, C. P., Pustovit, R. V., Lane, D. J., Jufar, A. H., Trask-Marino, A., . . . Lankadeva, Y. R. (2024). Reversal of cerebral ischaemia and hypoxia and of sickness behaviour by megadose sodium ascorbate in ovine Gram-negative sepsis. British Journal of Anaesthesia, 133(2), 316-325.
2024 Hulst, A. H., Ow, C. P. C., May, C. N., Hood, S. H., Plummer, M. P., Hermanides, J., . . . Lankadeva, Y. R. (2024). Effects of sodium-glucose transporter-2 inhibition on systemic hemodynamics, renal function, and intra-renal oxygenation in sepsis-associated acute kidney injury. Intensive Care Medicine Experimental, 12(1), 10 pages.
2023 Yanase, F., Spano, S., Maeda, A., Chaba, A., Naorungroj, T., Ow, C. P. C., . . . Bellomo, R. (2023). Mega-dose sodium ascorbate: a pilot, single-dose, physiological effect, double-blind, randomized, controlled trial. Critical Care, 27(1), 1-12.
Scopus3 Europe PMC12023 Plummer, M. P., Lankadeva, Y. R., & Bellomo, R. (2023). Apples and Oranges - All 'Vitamin C' May Not Be Created Equal. Critical Care Medicine, 51(12), E281-E282.
Scopus2 WoS1 Europe PMC12023 Turner, N., Farrow, B., Betrie, A. H., Finnis, M. E., Lankadeva, Y. R., Sharman, J., . . . Plummer, M. P. (2023). Cerebrospinal fluid and plasma ascorbate concentrations following subarachnoid haemorrhage. Critical Care and Resuscitation, 25(4), 175-181.
Scopus1 WoS12023 Tsigaras, Z. A., Weeden, M., McNamara, R., Jeffcote, T., Udy, A. A., Anstey, J., . . . Battistuzzo, C. (2023). The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management. Critical Care and Resuscitation, 25(4), 229-236.
2023 Wheatley, J., Liu, Z., Loth, J., Plummer, M. P., Penny‐Dimri, J. C., Segal, R., . . . Perry, L. A. (2023). The Prognostic Value of Elevated
<scp>Neutrophil‐Lymphocyte</scp>
Ratio for Cardiac Surgery Associated Acute Kidney Injury: A Systematic Review and
<scp>Meta‐Analysis</scp>. Acta Anaesthesiologica Scandinavica, 67(2), 131-141.
Scopus4 WoS1 Europe PMC32023 Jalleh, R. J., Umapathysivam, M. M., Plummer, M. P., Deane, A., Jones, K. L., & Horowitz, M. (2023). Postprandial plasma GLP-1 levels are elevated in individuals with postprandial hypoglycaemia following Roux-en-Y gastric bypass – a systematic review. Reviews in Endocrine and Metabolic Disorders, 24(6), 1075-1088.
Scopus4 Europe PMC22023 Zhu, V., Perry, L. A., Plummer, M., Segal, R., Smith, J., & Liu, Z. (2023). Diagnostic accuracy of brain natriuretic peptide and N-terminal-pro brain natriuretic peptide to detect complications of cardiac transplantation in adults: A systematic review and meta-analysis. Transplantation Reviews, 37(3), 13 pages.
Scopus12023 Lankadeva, Y. R., Lane, D. J., Ow, C. P., Story, D. A., Plummer, M. P., & May, C. N. (2023). LOVIT or leave it: The vitamin C debate continues. Critical Care and Resuscitation, 25(2), 63-64.
Scopus3 Europe PMC12023 Plummer, M. P., Rait, L., Finnis, M. E., French, C. J., Bates CCRN, S., Douglas, J., . . . Bhurani, M. (2023). Diabetes mellitus, glycaemic control and severe COVID-19 in the Australian Critical Care Setting – a nested cohort study. Australian Critical Care, 36(4), 579-585.
Scopus5 WoS2 Europe PMC32022 Begum, H., Neto, A. S., Alliegro, P., Broadley, T., Trapani, T., Campbell, L. T., . . . Burrell, A. (2022). People in intensive care with COVID-19: demographic and clinical features during the first, second, and third pandemic waves in Australia. Medical Journal of Australia, 217(7), 352-360.
Scopus27 WoS15 Europe PMC112022 Liu, Z., Karamesinis, A. D., Plummer, M., Segal, R., Bellomo, R., Smith, J. A., & Perry, L. A. (2022). Epidemiology of persistent postoperative opioid use after cardiac surgery: a systematic review and meta-analysis. British Journal of Anaesthesia, 129(3), 366-377.
Scopus12 WoS6 Europe PMC22022 Liu, Z., Perry, L. A., Penny-Dimri, J. C., Handscombe, M., Overmars, I., Plummer, M., . . . Smith, J. A. (2022). Elevated Cardiac Troponin to Detect Acute Cellular Rejection After Cardiac Transplantation: A Systematic Review and Meta-Analysis. Transplant International, 35, 13 pages.
Scopus4 WoS2 Europe PMC22022 Deane, A. M., Plummer, M. P., & Ali Abdelhamid, Y. (2022). Update on glucose control during and after critical illness. Current Opinion in Critical Care, 28(4), 389-394.
Scopus3 WoS1 Europe PMC22022 Plummer, M. P., Hermanides, J., & Deane, A. M. (2022). Is it time to personalise glucose targets during critical illness?. Current Opinion in Clinical Nutrition and Metabolic Care, 25(5), 364-369.
WoS12022 van Zuylen, M. L., Peters van Ton, A. M., Duindam, H. B., Scholten, E., van Dongen, E. P. A., ten Hoope, W., . . . Hermanides, J. (2022). Perioperative cerebrospinal fluid sorbitol and fructose concentrations in patients undergoing thoracic aortic surgery. British Journal of Anaesthesia, 129(3), e73-e76.
Scopus1 Europe PMC12022 Liu, Z., Penny-Dimri, J. C., Nagel, M., Plummer, M., Segal, R., Morley, P., . . . Perry, L. A. (2022). Early versus late surgical start times for on-pump cardiac surgery. Cochrane Database of Systematic Reviews, 2022(6).
2022 Raveendran, D., Penny-Dimri, J. C., Segal, R., Smith, J. A., Plummer, M., Liu, Z., & Perry, L. A. (2022). The prognostic significance of postoperative hyperbilirubinemia in cardiac surgery: systematic review and meta-analysis. Journal of Cardiothoracic Surgery, 17(1), 13 pages.
Scopus5 Europe PMC32022 Plummer, M. P., & Bellomo, R. (2022). Restrictive fluid therapy and high-dose vitamin C in sepsis. Nature Reviews Nephrology, 18(10), 607-608.
Scopus3 Europe PMC22022 Liu, Z., Perry, L. A., Penny-Dimri, J. C., Handscombe, M., Overmars, I., Plummer, M., . . . Smith, J. A. (2022). Prognostic Significance of Elevated Troponin in Adult Heart Transplant Recipients: A Systematic Review and Meta-Analysis. Experimental and Clinical Transplantation, 20(7), 633-641.
Scopus6 Europe PMC42022 Murthy, T. A., Plummer, M. P., Tan, E., Chapman, M. J., & Chapple, L. -A. S. (2022). Higher versus lower enteral calorie delivery and gastrointestinal dysfunction in critical illness: A systematic review and meta-analysis. Clinical Nutrition, 41(10), 2185-2194.
Scopus5 WoS4 Europe PMC12022 Jalleh, R. J., Xie, C., Deane, A. M., Plummer, M. P., Jones, K. L., Horowitz, M., & Kar, P. (2022). One-hour plasma glucose level after a 75 g oral glucose load and its relationship to gastric emptying in survivors of critical illness and stress hyperglycaemia. Critical Care and Resuscitation, 24(3), 268-271.
Scopus22022 Karri, R., Chen, Y. P. P., Burrell, A. J. C., Penny-Dimri, J. C., Broadley, T., Trapani, T., . . . Plummer, M. P. (2022). Machine learning predicts the short-term requirement for invasive ventilation among Australian critically ill COVID-19 patients. PLoS ONE, 17(10 October), 15 pages.
Scopus3 Europe PMC22022 Perry, L. A., Liu, Z., Loth, J., Penny-Dimri, J. C., Plummer, M., Segal, R., & Smith, J. (2022). Perioperative Neutrophil-Lymphocyte Ratio Predicts Mortality After Cardiac Surgery: Systematic Review and Meta-Analysis. Journal of Cardiothoracic and Vascular Anesthesia, 36(5), 1296-1303.
Scopus14 Europe PMC92022 van Gassel, R. J. J., van de Poll, M. C. G., Schaap, F. G., Plummer, M., Deane, A., & Olde Damink, S. W. M. (2022). Postprandial rise of essential amino acids is impaired during critical illness and unrelated to small-intestinal function. Journal of Parenteral and Enteral Nutrition, 46(1), 114-122.
Scopus6 WoS4 Europe PMC22021 Lankadeva, Y. R., Shehabi, Y., Deane, A. M., Plummer, M. P., Bellomo, R., & May, C. N. (2021). Emerging benefits and drawbacks of α₂-adrenoceptor agonists in the management of sepsis and critical illness. British Journal of Pharmacology, 178(6), 1407-1425.
Scopus22 WoS16 Europe PMC112021 Tan, E., Song, J., Deane, A. M., & Plummer, M. P. (2021). Global Impact of Coronavirus Disease 2019 Infection Requiring Admission to the ICU: A Systematic Review and Meta-analysis. Chest, 159(2), 524-536.
Scopus121 WoS92 Europe PMC882021 Deane, A. M., Ali Abdelhamid, Y., Plummer, M. P., Fetterplace, K., Moore, C., & Reintam Blaser, A. (2021). Are Classic Bedside Exam Findings Required to Initiate Enteral Nutrition in Critically Ill Patients: Emphasis on Bowel Sounds and Abdominal Distension. Nutrition in Clinical Practice, 36(1), 67-75.
Scopus9 WoS8 Europe PMC42021 Burrell, A. J. C., Pellegrini, B., Salimi, F., Begum, H., Broadley, T., Campbell, L. T., . . . Udy, A. A. (2021). Outcomes for patients with COVID-19 admitted to Australian intensive care units during the first four months of the pandemic. Medical Journal of Australia, 214(1), 23-30.
Scopus59 WoS54 Europe PMC442021 Chapple, L. -A. S., Plummer, M. P., & Chapman, M. J. (2021). Gut dysfunction in the ICU: diagnosis and management.. Current opinion in critical care, 27(2), 141-146.
Scopus9 WoS9 Europe PMC52021 Neto, A. S., Burrell, A. J. C., Bailey, M., Broadley, T., Cooper, D. J., French, C. J., . . . Udy, A. (2021). Comparison of critical care occupancy and outcomes of critically ill patients during the 2020 COVID-19 winter surge and 2009 H1N1 influenza pandemic in Australia. Annals of the American Thoracic Society, 18(8), 1380-1389.
Scopus11 Europe PMC72021 Burrell, A. J. C., Neto, A. S., Trapani, T., Broadley, T., French, C., Udy, A. A., . . . Waterson, S. (2021). Rapid translation of COVID-19 preprint data into critical care practice. American Journal of Respiratory and Critical Care Medicine, 203(3), 368-371.
Scopus7 WoS5 Europe PMC52021 Plummer, M. P., Lankadeva, Y. R., Finnis, M. E., Harrois, A., Harding, C., Peiris, R. M., . . . Deane, A. M. (2021). Urinary and renal oxygenation during dexmedetomidine infusion in critically ill adults with mechanistic insights from an ovine model. Journal of Critical Care, 64, 74-81.
Scopus5 WoS2 Europe PMC22021 Bowtell, M. K., Ankravs, M. J., Fazio, T., Presneill, J. J., Macisaac, C., Spence, M., . . . Deane, A. M. (2021). A microcosting analysis of ICU expenditure in the interval between brain death and organ donation. Critical Care and Resuscitation, 23(2), 211-214.
Europe PMC12021 Deane, A. M., Jiang, A., Tascone, B., Clancy, A., Finnis, M. E., Collie, J. T., . . . Ali Abdelhamid, Y. (2021). A multicenter randomized clinical trial of pharmacological vitamin B1 administration to critically ill patients who develop hypophosphatemia during enteral nutrition (The THIAMINE 4 HYPOPHOSPHATEMIA trial). Clinical Nutrition, 40(8), 5047-5052.
Scopus8 WoS42021 Kangisser, L., Tan, E., Bellomo, R., Deane, A. M., & Plummer, M. P. (2021). Neuroprotective Properties of Vitamin C: A Scoping Review of Pre-Clinical and Clinical Studies. Journal of Neurotrauma, 38(16), 2194-2205.
Scopus11 WoS5 Europe PMC102021 Tu, J. S. Y., Reeve, J., Deane, A. M., & Plummer, M. P. (2021). Pharmacological Management of Paroxysmal Sympathetic Hyperactivity: A Scoping Review. Journal of Neurotrauma, 38(16), 2221-2237.
Scopus7 WoS1 Europe PMC22021 Burrell, A. J. C., Neto, A. S., Broadley, T., Trapani, T., Begum, H., Campbell, L. T., . . . Udy, A. A. (2021). Comparison of baseline characteristics, treatment and clinical outcomes of critically ill COVID-19 patients admitted in the first and second waves in Australia. Critical Care and Resuscitation, 23(3), 308-319.
Scopus5 WoS4 Europe PMC22021 Liu, Z., Perry, L. A., Penny-Dimri, J. C., Handscombe, M., Overmars, I., Plummer, M., . . . Smith, J. A. (2021). Donor Cardiac Troponin for Prognosis of Adverse Outcomes in Cardiac Transplantation Recipients: A Systematic Review and Meta-analysis. Transplantation Direct, 8(1), e1261.
Scopus62020 Plummer, M. P., Pellegrini, B., Burrell, A. J. C., Begum, H., Trapani, T., & Udy, A. A. (2020). Smoking in critically ill patients with COVID-19: the Australian experience. Critical Care and Resuscitation, 22(3), 281-283.
Scopus4 WoS2 Europe PMC42019 Kar, P., Plummer, M., Ali Abdelhamid, Y., Giersch, E. J., Summers, M. J., Weinel, L. M., . . . Deane, A. M. (2019). Incident diabetes in survivors of critical illness and mechanisms underlying persistent glucose intolerance: a prospective cohort study. Critical Care Medicine, 47(2), 103-111.
Scopus9 WoS9 Europe PMC92019 Plummer, M. P., Hermanides, J., & Deane, A. M. (2019). Incretin Physiology and Pharmacology in the Intensive Care Unit. Critical Care Clinics, 35(2), 341-355.
Scopus6 WoS4 Europe PMC32019 Koelfat, K. V. K., Plummer, M. P., Schaap, F. G., Lenicek, M., Jansen, P. L. M., Deane, A. M., & Olde Damink, S. W. M. (2019). Gallbladder Dyskinesia Is Associated With an Impaired Postprandial Fibroblast Growth Factor 19 Response in Critically Ill Patients. Hepatology, 70(1), 308-318.
Scopus8 WoS7 Europe PMC62019 Plummer, M. P., Reintam Blaser, A., & Deane, A. M. (2019). Gut dysmotility in the ICU: diagnosis and therapeutic options. Current Opinion in Critical Care, 25(2), 138-144.
Scopus12 WoS7 Europe PMC52018 Hulst, A. H., Plummer, M. P., Hollmann, M. W., Devries, J. H., Preckel, B., Deane, A. M., & Hermanides, J. (2018). Systematic review of incretin therapy during peri-operative and intensive care. Critical Care, 22(1), 12 pages.
Scopus33 WoS21 Europe PMC162018 Hermanides, J., Plummer, M. P., Finnis, M., Deane, A. M., Coles, J. P., & Menon, D. K. (2018). Glycaemic control targets after traumatic brain injury: A systematic review and meta-analysis. Critical Care, 22(1), 11 pages.
Scopus56 WoS39 Europe PMC322018 Plummer, M. P., Notkina, N., Timofeev, I., Hutchinson, P. J., Finnis, M. E., & Gupta, A. K. (2018). Cerebral metabolic effects of strict versus conventional glycaemic targets following severe traumatic brain injury. Critical Care, 22(1), 8 pages.
Scopus15 WoS11 Europe PMC112018 Plummer, M. P., Young, A. M. H., O’Leary, R., Damian, M. S., & Lavinio, A. (2018). Probable Catastrophic Antiphospholipid Syndrome with Intracerebral Hemorrhage Secondary to Epstein–Barr Viral Infection. Neurocritical Care, 28(1), 127-132.
Scopus6 WoS5 Europe PMC42017 Young, A. M. H., Adams, H., Donnelly, J., Guilfoyle, M. R., Fernandes, H., Garnett, M. R., . . . Hutchinson, P. J. (2017). Glycemia is related to impaired cerebrovascular autoregulation after severe pediatric traumatic brain injury: A retrospective observational study. Frontiers in Pediatrics, 5, 7 pages.
Scopus6 WoS4 Europe PMC22017 Young, A. M. H., Adams, H., Donnelly, J., Guilfoyle, M. R., Fernandes, H., Garnett, M. R., . . . Hutchinson, P. J. (2017). Glycemia is related to impaired Cerebrovascular Autoregulation after Severe Pediatric traumatic Brain injury: A retrospective observational Study (vol 5, 205, 2017). FRONTIERS IN PEDIATRICS, 5, 1 page.
2017 Ovenden, C., Plummer, M., Selvanderan, S., Donaldson, T., Nguyen, N., Weinel, L., . . . Deane, A. (2017). Occult upper gastrointestinal mucosal abnormalities in critically ill patients. Acta Anaesthesiologica Scandinavica, 61(2), 216-223.
Scopus6 WoS4 Europe PMC52017 Kar, P., Jones, K. L., Plummer, M. P., Ali Abdelhamid, Y., Giersch, E., Summers, M. J., . . . Deane, A. M. (2017). Antecedent hypoglycemia does not attenuate the acceleration of gastric emptying by hypoglycemia. Journal of Clinical Endocrinology and Metabolism, 102(11), 3953-3960.
Scopus7 WoS8 Europe PMC42017 Abdelhamid, Y. A., Plummer, M. P., Finnis, M. E., Biradar, V., Bihari, S., Kar, P., . . . Deane, A. M. (2017). Long-term mortality of critically ill patients with diabetes who survive admission to the intensive care unit. Critical Care and Resuscitation, 19(4), 303-309.
Scopus10 WoS10 Europe PMC32017 Miller, A., Deane, A., Plummer, M., Cousins, C., Chapple, L., Horowitz, M., & Chapman, M. (2017). Exogenous glucagon-like peptide-1 attenuates glucose absorption and reduces blood glucose concentration after small intestinal glucose delivery in critical illness. Critical Care and Resuscitation, 19(1), 37-42.
Scopus11 WoS9 Europe PMC62016 Kar, P., Plummer, M. P., Bellomo, R., Jenkins, A. J., Januszewski, A. S., Chapman, M. J., . . . Deane, A. M. (2016). Liberal glycemic control in critically Ill patients with type 2 diabetes: an exploratory study. Critical Care Medicine, 44(9), 1695-1703.
Scopus42 WoS42 Europe PMC272016 Plummer, M., Finnis, M., Horsfall, M., Ly, M., Kar, P., Abdelhamid, Y., & Deane, A. (2016). Prior exposure to hyperglycaemia attenuates the relationship between glycaemic variability during critical illness and mortality. Critical Care and Resuscitation, 18(3), 189-197.
Scopus21 WoS18 Europe PMC92016 Selvanderan, S. P., Summers, M. J., Finnis, M. E., Plummer, M. P., Ali Abdelhamid, Y., Anderson, M. B., . . . Deane, A. M. (2016). Pantoprazole or placebo for stress ulcer prophylaxis (POP-UP): randomized double-blind exploratory study. Critical Care Medicine, 44(10), 1842-1850.
Scopus78 WoS61 Europe PMC542016 Ali Abdelhamid, Y., Kar, P., Finnis, M. E., Phillips, L. K., Plummer, M. P., Shaw, J. E., . . . Deane, A. M. (2016). Stress hyperglycaemia in critically ill patients and the subsequent risk of diabetes: a systematic review and meta-analysis.. Critical Care, 20(1), 301.
Scopus67 WoS47 Europe PMC442016 Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., . . . Deane, A. M. (2016). Stress induced hyperglycemia and the subsequent risk of type 2 diabetes in survivors of critical illness. PLoS One, 11(11), e0165923-12.
Scopus49 WoS36 Europe PMC262016 Kar, P., Plummer, M., Chapman, M., Cousins, C., Lange, K., Horowitz, M., . . . Deane, A. (2016). Energy-Dense Formulae May Slow Gastric Emptying in the Critically Ill. Journal of Parenteral and Enteral Nutrition, 40(7), 1050-1056.
Scopus17 WoS14 Europe PMC92016 Plummer, M., Kar, P., Cousins, C., Lange, K., Chapman, M., Nauck, M., . . . Deane, A. (2016). The insulinotropic effect of pulsatile compared with continuous intravenous delivery of GLP-1. Diabetologia, 59(5), 966-969.
Scopus1 WoS12016 Plummer, M., & Deane, A. (2016). Dysglycemia and glucose control during sepsis. Clinics in Chest Medicine, 37(2), 309-319.
Scopus39 WoS30 Europe PMC182016 Plummer, M., Kar, P., Cousins, C., Hausken, T., Lange, K., Chapman, M., . . . Deane, A. (2016). Critical illness is associated with impaired gallbladder emptying as assessed by 3D ultrasound. Critical Care Medicine, 44(9), e790-e796.
Scopus8 WoS9 Europe PMC72016 Liew, V. Y., Chapman, M. J., Nguyen, N. Q., Cousins, C. E., Plummer, M. P., Chapple, L. A. S., . . . Deane, A. M. (2016). A prospective observational study of the effect of critical illness on ultrastructural and microscopic morphology of duodenal mucosa. Critical Care and Resuscitation, 18(2), 102-108.
Scopus6 WoS6 Europe PMC52016 Plummer, M. P., & Lavinio, A. (2016). Stroke following inadvertent carotid artery catheterisation. Anaesthesia, 71(11), 1370.
Scopus2 WoS2 Europe PMC22015 Plummer, M. P., Kar, P., Cousins, C. E., Chapman, M. J., Hausken, T., Jones, K. L., . . . Deane, A. M. (2015). Nutrient-stimulated gallbladder emptying is incomplete during critical illness as assessed by 3D ultrasound. Intensive care medicine experimental, 3(Suppl 1). 2015 Selvanderan, S. P., Summers, M. J., Plummer, M. P., Finnis, M. E., Ali Abdelhamid, Y., Anderson, M. B., . . . Deane, A. M. (2015). Withholding Stress Ulcer Prophylaxis To Mechanically Ventilated Enterally-Fed Critically Ill Patients Appears Safe: A Randomised Double-Blind Placebo Controlled Pilot Study. Intensive care medicine experimental, 3(Suppl 1). 2015 Plummer, M. P., Kar, P., Cousins, C. E., Chapman, M. J., Hausken, T., Jones, K. L., . . . Deane, A. M. (2015). Nutrient-stimulated gallbladder emptying is incomplete during critical illness as assessed by 3D ultrasound. Intensive Care Medicine Experimental, 3(Suppl 1), A285.
2015 Summers, M. J., Selvanderan, S. P., Plummer, M. P., Finnis, M. E., Ali Abdelhamid, Y., Anderson, M. B., . . . Deane, A. M. (2015). Comparison of macroscopic abnormalities in patients receiving routine pantoprazole when compared to placebo. Intensive Care Medicine Experimental, 3(Suppl 1), A980.
2015 Selvanderan, S. P., Summers, M. J., Plummer, M. P., Finnis, M. E., Ali Abdelhamid, Y., Anderson, M. B., . . . Deane, A. M. (2015). Withholding stress ulcer prophylaxis to mechanically ventilated enterally-fed critically ill patients appears safe: A randomised double-blind placebo controlled pilot study. Intensive Care Medicine Experimental, 3(Suppl 1), A41.
Scopus32015 Kar, P., Plummer, M. P., Bellomo, R., Jenkins, A. J., Januszewski, A. S., Lange, K., . . . Deane, A. M. (2015). Personalised glucose therapy: Glucose targets in critically ill patients with pre-existing poorly controlled type 2 diabetes. Intensive Care Medicine Experimental, 3(Suppl 1), A290.
2015 Plummer, M., Jones, K., Cousins, C., Trahair, L., Meier, J., Chapman, M., . . . Deane, A. (2015). Hyperglycemia potentiates the slowing of gastric emptying induced by exogenous GLP-1. Diabetes Care, 38(6), 1123-1129.
Scopus27 WoS25 Europe PMC162014 Plummer, M., Blaser, A., & Deane, A. (2014). Stress ulceration: prevalence, pathology and association with adverse outcomes. Critical Care, 18(2), 1-7.
Scopus77 WoS48 Europe PMC402014 Plummer, M., Bellomo, R., Cousins, C., Annink, C., Sundararajan, K., Reddi, B., . . . Deane, A. (2014). Dysglycaemia in the critically ill and the interaction of chronic and acute glycaemia with mortality. Intensive Care Medicine, 40(7), 973-980.
Scopus155 WoS117 Europe PMC1012014 Plummer, M., Jones, K., Annink, C., Cousins, C., Meier, J., Chapman, M., . . . Deane, A. (2014). Glucagon-like peptide 1 attenuates the acceleration of gastric emptying induced by hypoglycemia in healthy subjects. Diabetes Care, 37(6), 1509-1515.
Scopus31 WoS27 Europe PMC242014 Plummer, M., Chapman, M., Horowitz, M., & Deane, A. (2014). Incretins and the intensivist: what are they and what does an intensivist need to know about them?. Critical Care, 18(1), 205-1-205-10.
Scopus13 WoS6 Europe PMC62013 Plummer, M., Meier, J., & Deane, A. (2013). The gut-brain axis in the critically ill: is glucagon-like peptide-1 protective in neurocritical care?. Critical Care, 17(4), 163-1-163-2.
Scopus3 WoS16 Europe PMC2- Bisiani, A., Redmond, J. M., Deane, A. M., & Plummer, M. P. (n.d.). Vaptans for the Management of Hyponatremia in Neurocritical Care: a Systematic Review. SN Comprehensive Clinical Medicine, 4(1).
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Book Chapters
Year Citation 2016 Plummer, M., Blaser, A., & Deane, A. (2016). Enterohormones and the response to critical illness. In J. -C. Preiser (Ed.), The Stress Response of Critical Illness: Metabolic and Hormonal Aspects (pp. 153-168). Switzerland: Springer.
Scopus2 -
Conference Papers
Year Citation 2016 Selvanderan, S. P., Summers, M., Finnis, M., Plummer, M., Abdelhamid, Y. A., Anderson, M., . . . Deane, A. M. (2016). Administration of Stress Ulcer Prophylaxis May Cause Harm in Critically Ill Patients: A Randomized Double Blind Exploratory Study. In GASTROENTEROLOGY Vol. 150 (pp. S882). San Diego, CA: W B SAUNDERS CO-ELSEVIER INC.
WoS12015 Plummer, M. P., Jones, K. L., Cousins, C. E., Trahair, L. G., Meier, J. J., Chapman, M. J., . . . Deane, A. M. (2015). Hyperglycemia Potentiates the Slowing of Gastric Emptying Induced by Exogenous GLP-1. In DIABETES Vol. 64 (pp. A283-A284). Boston, MA: AMER DIABETES ASSOC. -
Conference Items
Year Citation 2022 Jalleh, R. J., Umapathysivam, M., Louise, J., Plummer, M. P., Deane, A., Jones, K. L., & Horowitz, M. (2022). Incretin hormone and glucoregulatory responses to nutrients in individuals with and without post-bariatric hypoglycaemia: a systematic review. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm & Online: Springer.
2016 Kar, P., Plummer, M. P., Giersch, E., Summers, M. J., Hatzinikolas, S., Horowitz, M., . . . Deane, A. (2016). Effects of antecedent hypoglycaemia on gastric and cardiac responses to subsequent hypoglycaemia in health. Poster session presented at the meeting of DIABETOLOGIA. Munich, GERMANY: SPRINGER. 2014 Deane, A. M., Plummer, M. P., Cousins, C. E., Annink, C. E., Sundararajan, K., Reddi, B. A., . . . Bellomo, R. (2014). The Impact Of Premorbid Glycemia On The Association Between Acute Hyperglycemia And Mortality In Critically Ill Patients. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC. 2014 Plummer, M. P., Kar, P., Chapman, M. J., Cousins, C. E., Heyland, D. K., Horowitz, M., . . . Deane, A. M. (2014). INCREASING CALORIE CONTENT SLOWS GASTRIC EMPTYING IN THE CRITICALLY ILL. Poster session presented at the meeting of INTENSIVE CARE MEDICINE. Barcelona, SPAIN: SPRINGER. 2014 Cousins, C. E., Miller, A., Plummer, M. P., Deane, A. M., Horowitz, M., & Chapman, M. J. (2014). THE EFFECT OF EXOGENOUS GLUCAGON LIKE PEPTIDE-1 (GLP-1) ON SMALL INTESTINAL GLUCOSE MISORPTION UN THE CRITICALLY ILL. Poster session presented at the meeting of INTENSIVE CARE MEDICINE. Barcelona, SPAIN: SPRINGER. 2013 Plummer, M. P., Zaknic, A. V., Reddi, B. A., Raj, J., Sundararajan, K., Chapman, M. J., . . . Deane, A. M. (2013). The prevalence of unrecognised diabetes and critical-illness induced hyperglycaemia in critically ill patients: a prospective observational study. Poster session presented at the meeting of Abstracts of Oral Presentations and Poster Sessions of the 26th Annual Congress of the European Society of Intensive Care Medicine, as published in Intensive Care Medicine. Paris, France: Springer Berlin Heidelberg.
2013 Plummer, M. P., Crowhurst, T. D., Annink, C. E., Cousins, C. E., Sardana, R. R., Meier, J. J., . . . Deane, A. M. (2013). GLP-1 attenuates the acceleration of gastric emptying induced by hypoglycaemia in healthy subjects. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
2021
- The Hospital Research Foundation Group Early Career Fellowship:
Plummer MP. Mega-dose vitamin C for the management of septic shock, Value $390,000
- Intensive Care Foundation Project Grant
Reeve J, Plummer MP, Deane AM, Ankravs M, Cavric A. Cannabis in paroxysmal sympaethetic hyperactivity. Value $5000
- Intensive Care Foundation Project Grant
Surace S, Plummer MP, Deane AM, Macisaac C, Ankravs M, Adamson N. Prospective observational study of biochemically verified nicotine use in a critically ill population compared with self-reporting and collateral history. Value $5000
- Diabetes Australia Research Trust General Grant
Horowitz M, Chapman MJ, Plummer MP, Jones KL, Deane AM, Rayner C. Management of critical illness-indiuced (‘stress’) hyperglyacemia with native glucagon-like peptide-1 (GLP-1). Value $60,000
2016
- Diabetes Australia Research Trust General Grant
Philips LK, Horowitz M, Shaw JE, Deane AM, Plummer MP. Glycaemia in the critically ill – dysglyaemia as a predictor for incident type 2 diabetes and the effect of pre-existing type 2 diabetes on outcomes in survivors of critical illness. Value $59, 915
- South Australia Intensive Care Association Research Assistance Program
Plummer MP, Finnis ME, Phillips LK, Kar P, Bihari S, Biradar V, Moodie S, Horowitz M, Shaw JE, Deane AM. Stress induced hyperglycaemia and the subsequent risk of type 2 diabetes in survivors of critical illness.Value $2,000
2015
- Royal Adelaide Hospital Research Foundation, Clinical Project Grant
Plummer MP, Deane AM, Chapman MJ, Jones KL, Hausken T. The effect of critical illness on gallbladder motility, lipid absorption and plasma cholecystokinin concentrations. Value $49,565
- Maurice Sando Foundation Grant
Plummer MP, Deane AM, Finnis ME, Shaw JE, Moodie S, Biradar V. A state-wide study to determine whether hyperglycaemia during critical illness identifies survivors at risk of subsequently developing diabetes. Value $10,000
2014
- National Health and Medical Research Council Postgraduate Scholarship
Plummer MP. Patient safety and therapeutic implications of a new glucose lowering agent for type 2 diabetes and high blood glucose states in the critically ill. GNT1075657. Value $84,905
- Royal Adelaide Hospital Research Foundation, Clinical Project Grant
Plummer MP, Deane AM, Chapman MJ, Rayner C. The effect of routine pantoprazole administration when compared to placebo on gastrointestinal bleeding, ventilator-associated pneumonia and Clostridium difficile infection in enterally-fed mechanically ventilated critically ill patients: A prospective randomised study. Value: $49,139
- Inaugural Intensive Care Foundation Trainee Grant
Plummer MP, Deane AM, Chapman MJ, Horowitz M, Jones K. Gallbladder motility in critical illness. Value $5,000
Editor e-Medici: 2019 - present
Examiner: University of Adelaide Medical School OSCE's: 2021 - present
Australian Medical Council Examination writing committee: 2015 - present
CICM primary examination course lecturer: 2013 - present
Convener: University of Melbourne Department of Critical Care Postgraduate Research Seminar 2020-21
Professor Derek Frewin AO Citation for clinical teaching 2011, 2013
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 Co-Supervisor Novel pathophysiology and therapeutics in acute brain injury Doctor of Philosophy Doctorate Full Time Dr Tim Paul Webber 2023 Co-Supervisor Mitigating the short and long-term complications of stress hyperglycaemia Doctor of Philosophy Doctorate Full Time Mr Aniket Nadkarni 2022 Co-Supervisor Enteral protein delivery in the critically ill Doctor of Philosophy Doctorate Full Time Mr Matthew Summers -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2022 - ongoing Principal Supervisor Neuroprotection post subarachnoid haemorrhage University of Melbourne - Honours - Ms Lauren Kassinger 2021 - ongoing Principal Supervisor Paroxysmal sympathetic hyperactivity University of Melbourne University of Melbourne MD Research Project Other - Mr Justin Tu 2021 - ongoing Principal Supervisor CSF anti-oxidants post subarachnoid haemorrhage University of Melbourne - Honours - Ms Natasha Turner 2019 - ongoing Principal Supervisor Vasospasm prevention post subarachnoid haemorrhage University of Melbourne University of Melbourne MD Research Project Other - Ms Lauren Sperring
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Committee Memberships
Date Role Committee Institution Country 2022 - ongoing Co-Chair Asia-Pacific Intensive Care Society ASM Management committee Asia-Pacific Intensive Care Society Australia 2021 - ongoing Member PRECISION-TBI steering committee PRECISION TBI Australia 2021 - ongoing Member ANZICS-CTG protocol review panel ANZICS-Clinical Trials Group Australia 2020 - ongoing Member ANZICS Global Health Special Interest Group Australia and New Zealand Intensive Care Society Australia 2020 - ongoing Member ANZICS COVID-19 SPRINT-SARI Australia Management Committee Australia and New Zealand Intensive Care Society Australia -
Memberships
Date Role Membership Country 2012 - ongoing Member Australia and New Zealand Intensive Care Society Australia 2012 - ongoing Member College of Intensive Care Medicine Australia
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