Dr Tongzhi Wu
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Dr Tongzhi Wu leads a research team within the NHMRC Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health at the University of Adelaide, using sophisticated techniques to gain important insights into how ingested nutrients interact with the gut in health and disease. He is particularly interested in how the gut “tastes” meal contents, especially bitter tasting substances. He is embarking on exciting new research funded by the National Health and Medical Research Council (NHMRC), Diabetes Australia, the Royal Adelaide Hospital (RAH) Research Foundation, and the University of Adelaide, to understand how the sensing of bitter substances in the gut can regulate appetite and blood glucose levels. The outcomes of Dr Wu’s research program have the potential to establish new, safe and inexpensive treatments for type 2 diabetes.
-
Expand
-
Appointments
Date Position Institution name 2018 Adjunct Senior Fellow University of Adelaide, Adelaide 2018 - 2020 Royal Adelaide Hospital Florey Fellow Royal Adelaide Hospital, Adelaide 2014 - 2017 Royal Adelaide Hospital Mary Overton Fellow University of Adelaide 2014 - 2014 NHMRC Clinical Research Fellow University of Adelaide, Adelaide 2007 - 2009 Basic Physician Trainee Zhongda Hospital Southeast University 2006 - 2007 Intern (First Class) Zhongda Hospital Southeast University -
Awards and Achievements
Date Type Title Institution Name Country Amount 2016 Award Executive Dean's Award for Research Excellence (Early Career Researcher) The University of Adelaide — — 2016 Award Travel Award European Association for the Study of Diabetes — €1500 2016 Award Travel Award University of Adelaide, School of Medicine Australia 2835 2015 Fellowship Early Career Fellowship Royal Adelaide Hospital Australia — 2015 Recognition Best Poster Australian Diabetes Society Australia — 2015 Award Travel Grant University of Adelaide, Discipline of Medicine Australia — 2014 Research Award University Doctoral Research Medal University of Adelaide Australia — 2013 Recognition Dean's commendation for thesis excellence University of Adelaide Australia — 2013 Award Travel Award, Diabetes Congress International Diabetes Federation (IDF) Australia — 2013 Fellowship Travelling Fellowship University of Adelaide, Discipline of Medicine Australia 2600 2012 Award Travel Award European Association for the Study of Diabetes — €2000 2011 Award Travel Award European Association for the Study of Diabetes — €2000 2011 Fellowship Postgraduate Travelling Fellowship University of Adelaide Australia 1700 2010 Recognition Best Poster Presentation University of Adelaide, Research Expo Australia — 2009 Recognition Outstanding Postgraduate in Clinical Medicine Southeast University Australia — 2009 Scholarship Postgraduate Scholarship China Scholarship Council China — 2009 Scholarship Postgraduate Supplementary Scholarship Centre of Research Excellence in Translating Nutritional Science to Good Health Australia — 2007 Scholarship First-class postgraduate scholarship Southeast University China — 2007 Recognition Outstanding Graduate in Clinical Medicine Southeast University China — 2006 Recognition 'Excellent Student Researcher' in the Student Research Training Program (SRTP) Southeast University China — 2004 Scholarship 'Zi-guang' Scholarship Southeast University Australia — -
Education
Date Institution name Country Title 2009 - 2013 University of Adelaide Australia Doctor of Philosophy 2007 - 2009 Southeast University China Master of Clinical Medicine 2002 - 2007 Southeast University China Bachelor of Clinical Medicine
-
Expand
-
Journals
-
Book Chapters
Year Citation 2017 Whey Protein and Diabetes (2017). In Dairy in Human Health and Disease across the Lifespan (pp. 197-209).
Scopus12016 Wu, T., Rayner, C. K., & Horowitz, M. (2016). Incretins. In S. Herzig (Ed.), Metabolic Control (Vol. 233, pp. 137-171). Switzerland: Springer.
Scopus21 Europe PMC13 -
Conference Papers
Year Citation 2018 Borg, M., Rayner, C., Horowitz, M., Jones, K., & Wu, T. (2018). Metformin attenuates the fall in postprandial blood pressure and slows gastric emptying in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S112). Berlin, GERMANY: SPRINGER. 2018 Veedfald, S., Wu, T., Bound, M., Grivell, J., Hartmann, B., Rehfeld, J., . . . Rayner, C. (2018). Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men. In The Journal of clinical endocrinology and metabolism Vol. 103 (pp. 4409-4418). United States: WILEY.
2018 Bitarafan, V., Fitzgerald, P., Little, T., Wu, T., Horowitz, M., & Feinle-Bisset, C. (2018). Effects of intraduodenal infusion of the bitter tastant, quinine, on antropyloroduodenal motility, plasma cholecystokinin concentrations and energy intake in humans. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 30 (pp. 1 page). WILEY. 2018 Jones, K., Stevens, J., Buttfield, M., Wu, T., Hatzinikolas, S., Pham, H., . . . Horowitz, M. (2018). The reduction in postprandial glucose by sitagliptin is related to the rate of gastric emptying in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S381). Berlin, GERMANY: SPRINGER. 2018 Trahair, L., Nauck, M., Wu, T., Buttfield, M., Stevens, J., Hatzinikolas, S., . . . Jones, K. (2018). Measurement of gastric emptying using scintigraphy and a C-13-octanoic acid breath test with Wagner-Nelson analysis in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S338-S339). Berlin, GERMANY: SPRINGER. 2018 Borg, M., Bound, M., Grivell, J., Sun, Z., Jones, K., Horowitz, M., . . . Wu, T. (2018). Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes. In Diabetes, Obesity and Metabolism Vol. 61 (pp. S112-S113). Berlin, GERMANY: SPRINGER.
Scopus12018 Rayner, C., Watson, L., Phillips, L., Bound, M., Grivell, J., Wu, T., . . . Natali, A. (2018). Effects of sustained treatment with lixisenatide on gastric emptying and glucose metabolism in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S386-S387). Berlin, GERMANY: SPRINGER. 2015 Marathe, C., Thazhath, S. S., Wu, T., Horowitz., Jones, K. L., & Rayner, C. K. (2015). Effects of Glucagon-like peptide -1 (GLP-1) receptor agonist, exenatide, on small intestinal motility, and glucose absorption in health and type 2 diabetes. In Diabetes. Adelaide. 2015 Marathe, C., Thazhath, S. S., Wu, T., Horowitz, M., Jones, K. L., & Rayner, C. K. (2015). Effects of glucagon-like peptide -1 (GLP-1) receptor agonist, exenatide, on blood pressure and heart rate during duodenal glucose infusion in type 2 diabetes. In Diabetes. Adelaide. 2012 Bound, M., Wu, T., Gedulin, B., Horowitz, M., & Rayner, C. (2012). Effects of bile acid enemas on GLP-1 and PYY secretion in healthy humans. In Diabetologia Vol. 55 (pp. S338). Germany: Springer.
2012 Zhao, R., Wu, T., Jones, K., Horowitz, M., & Rayner, C. (2012). Effects of a D-xylose preload, with or without sitagliptin, on gastric emptying and postprandial glycaemia in patients with type 2 diabetes. In Journal of Gastroenterology and Hepatology Vol. 27 (pp. 148-149). Australia: Wiley-Blackwell.
2011 Wu, T., Zhao, B., Bound, M., Checklin, H., Bellon, M., Little, T., . . . Rayner, C. (2011). Effects of different sweet preloads on incretin hormone responses, gastric emptying and postprandial glycaemia in healthy humans. In DIABETOLOGIA Vol. 54 (pp. S330). Lisbon, PORTUGAL: SPRINGER. 2010 Wu, T., Zhao, B., Bound, M., Checklin, H., Bellon, M., Little, T., . . . Rayner, C. (2010). Effects of sweet preloads on gastric emptying and postprandial glycaemia in healthy subjects. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 25 (pp. A105). WILEY-BLACKWELL PUBLISHING, INC. 2010 Ma, J., Wu, T., Checklin, H., Wishart, J., Stevens, J., Jones, K., . . . Rayner, C. (2010). Effects of enterically coated, nutrient-containing pellets on glycaemia and incretin hormone release in type 2 diabetes. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 25 (pp. A114-A115). WILEY-BLACKWELL PUBLISHING, INC. -
Conference Items
| Years | Funding details |
|---|---|
| 2018-20 |
NHMRC Project Grant (APP114733) - Bitter taste as a mediator of food intake and postprandial glycaemia in health and type 2 diabetes. Wu T, Rayner CK, Jones KL, Young RL and Feinle-Bisset C. ($725,276) |
| 2018-20 | Royal Adelaide Hospital (RAH) Research Foundation Florey Fellowship - Bitter taste as a mediator of food intake and postprandial glycaemia in health and type 2 diabetes. Wu T. ($348,000) |
| 2018-19 | Diabetes Australia Millennium Grant - Do artificial sweeteners affect glycaemic control in T2DM adversely? Young RL, Rayner CK, Horowitz M, Wu T. ($150,000) |
| 2018 | Royal Adelaide Hospital (RAH) Research Foundation Clinical Project Grant - Role of endogenous glucose-dependent insulinotropic polypeptide in the gastric emptying, glycaemia, splanchnic blood flow and blood pressure responses to oral glucose in healthy older subjects. Jones KL, Rayner CK, Wu T, Bartholomeusz D, Horowitz M, Veedfald S, Holst J, Rosenkilde M, Deacon C. ($49,472) |
| 2018 | Royal Adelaide Hospital (RAH) Research Foundation Clinical Project Grant - Molecular events linking artificial sweetener intake to augmented glucose absorption and dysglycaemia in health and type 2 diabetes. Young RL, Nguyen N, Rayner CK, Wu T. ($49,710) |
| 2017-18 |
Project Development Award of NHMRC Centre of Research Excellence in Translating Nutritional Science to Good Health - Effects of the bitter taste agonist, denatonium benzoate, on energy intake and postprandial glycaemia in health and type 2 diabetes. Wu T. ($32,610) |
| 2017-18 |
The University of Adelaide Early Career Researcher Mentored Project Development Grant - Nutrient-gut interactions and glycaemic control in type 2 diabetes. Wu T ($14,992) |
| 2017-18 | Diabetes Australia General Grant - Gastrointestinal mechanisms of the anti-diabetic effect of metformin. Wu T, Rayner CK, Horowitz M.
($59,270) |
| 2017 |
The University of Adelaide Research Infrastructure Funding Awards - LOGIQ eR7 Ultrasound System to measure 2D and Doppler ultrasound in nutrition research. Jones KL, Rayner CK, Feinle-Bisset C, Wu T, Soenen S ($26,410) |
| 2016-17 |
Royal Adelaide Hospital (RAH) Research Foundation Clinical Project Grant - Does intestinal bitter taste sensing modulate gastrointestinal motility and hormone secretion to reduce glycaemia and energy intake in humans? Wu T, Rayner CK. ($49,258) |
| 2015-17 |
Royal Adelaide Hospital (RAH) Research Committee Early Career Fellowship - The “gut-incretin” axis in the regulation of postprandial glycaemia in type 2 diabetes. Wu T. ($252,000) |
| 2015 |
The University of Adelaide Interdisciplinary Seed Funding - Fibre insight in diabetes treatment: a new photonic fibre device to investigate the enteroendocrine L-cells. Zhao J, Wu T. ($22,000) |
| 2014-16 |
Royal Adelaide Hospital (RAH) Research Foundation Clinical Project Grant - Intestinal sweet taste receptor control of glucose absorption in human health & type 2 diabetes. Young RL, Wu T, Rayner CK. ($40,000) |
| 2014-16 | Royal Adelaide Hospital (RAH) Research Foundation Clinical Project Grant - Effects of DPP-4 inhibition with sitagliptin on postprandial blood pressure, glycaemia and incretin hormones in type 2 diabetes – relationship to gastric emptying. Jones KL, Wu T, Rayner CK. ($49,700) |
| 2014 |
Clinical Research Fellowship, NHMRC Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health - “Gut-based” approaches to the management of type 2 diabetes. Wu T. ($80,571) |
-
Expand
-
Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2017 Co-Supervisor Bitter Taste Control of Blood Glucose Homeostasis Doctor of Philosophy Doctorate Full Time Mr Cong Xie 2017 Co-Supervisor The fabrication of a multiplexing Optimal fibre sensor to detect metal ion and glucose. Master of Philosophy Master Full Time Mr Weikun Huang
-
Expand
-
Committee Memberships
Date Role Committee Institution Country 2015 - ongoing Member Australian Diabetes Society — Australia 2009 - ongoing Member European Association for the Study of Diabetes — —
Connect With Me
