Weikun Huang

Health and Medical Sciences Faculty Office

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Weikun's work focuses on developing organ-on-chip platform for studying the endocrine functions of gut and pancreas and the identification of novel therapeutic targets for type 2 diabetes (T2D). He is also interested in understanding the gut and pancreatic hormone secretion in health and T2D.

Career
Publications
Grants and Funding
Supervision
Professional Activities
Contact

Appointments

Date Position Institution name

2023 - ongoing Grant-funded researcher University of Adelaide

2019 - 2023 PhD candidate The University of Adelaide

Date	Position	Institution name
2023 - ongoing	Grant-funded researcher	University of Adelaide
2019 - 2023	PhD candidate	The University of Adelaide

Awards and Achievements

Date	Type	Title	Institution Name	Country	Amount
2023	Award	Travel Grant	Australian Diabetes Society	Australia	350
2023	Award	Travel Grant	European Association for the Study of Diabetes	Germany	€2,000
2023	Award	Pincus Taft Young Investigator Award (Finalist)	Australian Diabetes Society	Australia	-
2022	Award	Travel Award	Australian Diabetes Society	Australia	700
2022	Award	Best Student Paper Award	Institute of Photonics and Advanced Sensing	Australia	500
2022	Research Award	Adelaide Medical School Travel Grant	Adelaide Medical School, The University of Adelaide	Australia	3,500
2022	Research Award	Travel Grant	Adelaide Graduate and Research School, The University of Adelaide	Australia	2,500
2022	Award	Travel Grant	European Association of the Study of Diabetes	Germany	€1,400
2022	Award	Basic Science Poster Award (Finalist)	Australian Diabetes Society	Australia	-
2022	Award	Clinical Poster Award (Finalist)	Australian Diabetes Society	Australia	-
2021	Award	Best Transdisciplinary Paper Award	Institute of Photonics and Advanced Sensing, The University of Adelaide	Australia	500
2020	Award	ADS-Abbott Registration Grant	Australian Diabetes Society	Australia	250
2020	Award	Pincus Taft Young Investigator Award (Finalist)	Australian Diabetes Society	Australia	-
2019	Award	People's Choice for Best Oral Presentation	Institute of Photonics and Advanced Sensing, The University of Adelaide	Australia	-
2019	Scholarship	NHMRC-funded supplementary scholarship	The University of Adelaide	Australia	5,000 per annum
2019	Scholarship	Adelaide Graduate Research Scholarship	The University of Adelaide	Australia	32,500 per annum
2019	Award	Travel Award	ARC Centre of Excellence for Nanoscale BioPhotonics, The University of Adelaide	Australia	-

Language Competencies

Language Competency

Chinese (Mandarin) Can read, write, speak, understand spoken and peer review

English Can read, write, speak, understand spoken and peer review

Language	Competency
Chinese (Mandarin)	Can read, write, speak, understand spoken and peer review
English	Can read, write, speak, understand spoken and peer review

Education

Institution name	Country	Title
Jilin University	China	Bachelor's degree in Agriculture (Veterinary Medicine)
Jilin University	China	Bachelor's degree in Art (English), dual degree
The University of Adelaide	Australia	Master of Philosophy in Physics
The University of Adelaide	Australia	Doctor of Philosophy in Medicine

Research Interests

Innovative Therapeutics Nutrition and Metabolic Health Analytical Chemistry Biomedical Engineering Endocrinology & Metabolism Optical Physics Sensor Technology Microfluidics and nanofluidics Tissue engineering

Journals

Year	Citation
2024	Huang, W., O'Hara, S. E., Xie, C., Liu, N., Rayner, C. K., Nicholas, L. M., & Wu, T. (2024). Effects of a bitter substance, denatonium benzoate, on pancreatic hormone secretion. American Journal of Physiology: Endocrinology and Metabolism, 326(4), E537-E544. DOI
2024	Xie, C., Iroga, P., Bound, M. J., Grivell, J., Huang, W., Jones, K. L., . . . Wu, T. (2024). Impact of the timing of metformin administration on glycaemic and glucagon-like peptide-1 responses to intraduodenal glucose infusion in type 2 diabetes: a double-blind, randomised, placebo-controlled, crossover study. Diabetologia, 67(7), 1260-1270. DOI Scopus4 Europe PMC2
2024	Xiang, C., Sun, Y., Luo, Y., Xie, C., Huang, W., Sun, Z., . . . Wu, T. (2024). Gastric emptying of a glucose drink is predictive of the glycaemic response to oral glucose and mixed meals, but unrelated to antecedent glycaemic control, in type 2 diabetes. Nutrition and Diabetes, 14(1), 13-1-13-7. DOI Scopus2
2024	Xiang, C., Sun, Y., Luo, Y., Xie, C., Huang, W., Jones, K. L., . . . Wu, T. (2024). Gastric emptying is slower in women than men with type 2 diabetes and impacts on postprandial glycaemia. Diabetes, Obesity and Metabolism, 26(8), 3119-3127. DOI Scopus2
2024	Sun, Y., Luo, Y., Xiang, C., Xie, C., Huang, W., Sun, Z., . . . Wu, T. (2024). Gastric emptying in newly diagnosed, treatment-naïve Han Chinese with type 2 diabetes and the impact of 4-week insulin pump therapy. Diabetes, Obesity and Metabolism, 26(8), 3078-3087. DOI Scopus1
2024	Xie, C., Huang, W., Rayner, C. K., Horowitz, M., & Wu, T. (2024). Letter to the Editor From Xie et al: "The 13C Glucose Breath Test Accurately Identifies Insulin Resistance in People With Type 1 Diabetes".. The Journal of clinical endocrinology and metabolism, 109(10), dgae366. DOI
2024	Huang, W., Xie, C., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2024). Sex differences in the plasma glucagon responses to a high carbohydrate meal and a glucose drink in type 2 diabetes. Diabetes Research and Clinical Practice, 214, 3 pages. DOI Scopus2
2024	Li, T., Sang, M., Wang, J., Sun, Z., Wang, D., Xie, C., . . . Wu, T. (2024). Dark tea consumption is associated with a reduced risk of dysglycaemia and increased urinary glucose and sodium excretion in Chinese adults. Diabetes, Obesity and Metabolism, 26(10), 4705-4712. DOI
2024	Huang, W., Xie, C., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2024). Reply to 'Letter to the Editor: Sex differences in the plasma glucagon responses to a high carbohydrate meal and a glucose drink in type 2 diabetes'.. Diabetes Res Clin Pract, 217, 111880. DOI
2023	Huang, W., Xie, C., Wewer Albrechtsen, N. J., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2023). The 'early' postprandial glucagon response is related to the rate of gastric emptying in patients with type 2 diabetes. Peptides, 161, 170941-1-170941-7. DOI Scopus4 WoS1
2023	Xie, C., Jalleh, R. J., Watson, L. E., Huang, W., Sun, Y., Jones, K. L., . . . Wu, T. (2023). Determinants of blood glucose concentrations following a high carbohydrate meal in type 2 diabetes: A multiple linear regression analysis. Diabetes Research and Clinical Practice, 198, 110606. DOI Scopus4 Europe PMC2
2023	Xie, C., Huang, W., Sun, Y., Xiang, C., Trahair, L., Jones, K. L., . . . Wu, T. (2023). Disparities in the glycaemic and incretin responses to intraduodenal glucose infusion between healthy young men and women. Journal of Clinical Endocrinology and Metabolism, 108(9), e712-e719. DOI Scopus13 WoS2 Europe PMC6
2023	Huang, W., Xie, C., Wewer Albrechtsen, N. J., Sang, M., Sun, Z., Jones, K. L., . . . Wu, T. (2023). Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes. Peptides, 169, 171092-1-171092-10. DOI Scopus3
2022	Huang, W., Wu, T., Xie, C., Rayner, C. K., Priest, C., Ebendorff-Heidepriem, H., & Zhao, J. (2022). Sensing Intra- and Extra-Cellular Ca2+ in the Islet of Langerhans. Advanced Functional Materials, 32(3), 24 pages. DOI Scopus2
2022	Xie, C., Huang, W., Watson, L. E., Soenen, S., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Plasma GLP-1 response to oral and intraduodenal nutrients in health and type 2 diabetes - impact on gastric emptying. The Journal of Clinical Endocrinology & Metabolism, 107(4), e1643-e1652. DOI Scopus20 WoS11 Europe PMC12
2022	Wang, X., Chen, C., Xie, C., Huang, W., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Serum bile acid response to oral glucose is attenuated in patients with early type 2 diabetes and correlates with 2h plasma glucose in individuals without diabetes.. Diabetes, obesity & metabolism, 24(6), 1134-1142. DOI Scopus9 WoS6 Europe PMC7
2021	Xie, C., Huang, W., Wang, X., Trahair, L. G., Pham, H. T., Marathe, C. S., . . . Wu, T. (2021). Gastric emptying in health and type 2 diabetes: an evaluation using a 75g oral glucose drink. Diabetes Research and Clinical Practice, 171, 1-8. DOI Scopus20 WoS9 Europe PMC8
2021	Xie, C., Huang, W., Young, R. L., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2021). Role of bile acids in the regulation of food intake, and their dysregulation in metabolic disease. Nutrients, 13(4), 1-16. DOI Scopus63 WoS44 Europe PMC40
2021	Palasis, K. A., Lokman, N. A., Quirk, B. C., Adwal, A., Scolaro, L., Huang, W., . . . Abell, A. D. (2021). Optical fibre-enabled photoswitching for localised activation of an anti-cancer therapeutic drug. International Journal of Molecular Sciences, 22(19), 10844-1-10844-10. DOI Scopus5 WoS3 Europe PMC2
2020	Huang, W., Wu, T., Shallan, A., Kostecki, R., Rayner, C. K., Priest, C., . . . Zhao, J. (2020). A multiplexed microfluidic platform towards interrogating endocrine function: simultaneous sensing of extracellular Ca²⁺ and hormone. ACS Sensors, 5(2), 490-499. DOI Scopus6 WoS4 Europe PMC2
2020	Huang, W., Xie, C., Young, R. L., Zhao, J., Ebendorff-Heidepriem, H., Jones, K. L., . . . Wu, T. (2020). Development of innovative tools for investigation of nutrient-gut interaction. World Journal of Gastroenterology, 26(25), 3562-3576. DOI Scopus8 WoS7 Europe PMC3
2016	Deng, Q., Ma, D., Shi, Z., Huang, W., Du, X., Gao, W., . . . Li, X. (2016). Effects of β-hydroxybutyricacid on the synthesis and assembly of very low-density lipoprotein in bovine hepatocytes in vitro. Journal of Animal Physiology and Animal Nutrition, 100(2), 331-336. DOI Scopus1 WoS1
2015	Li, X., Huang, W., Gu, J., Du, X., Lei, L., Yuan, X., . . . Liu, G. (2015). SREBP-1c overactivates ROS-mediated hepatic NF-κB inflammatory pathway in dairy cows with fatty liver. Cellular Signalling, 27(10), 2099-2109. DOI Scopus106 WoS94 Europe PMC45

2024 UK Reserach and Innovation Grant (£161,994)

Project Title: Sensing and signalling of extracellular Ca²⁺ in the islet of Langerhans

Chief Investigators: Jiangbo Zhao, Weikun Huang

2023 Diabetes Australia Project Grant (ID: Y24G-XIEC) ($59,995)

Project title: Development of a novel bile acid-based therapy to optimise postprandial glycaemic control in type 2 diabetes

Chief Investigators: Cong Xie, Tongzhi Wu, Richard Young, Michael Horowitz, Weikun Huang

2023 Diabetes Australia Project Grant (ID: Y23G-WUTO) ($70,000)

Project title: Harnessing bile acid sensing mechanisms to improve the management of type 2 diabetes.

Chief Investigators: Tongzhi Wu, Chris Rayner, Richard Young, Michael Horowitz, Karen Jones, Cong Xie, Heike Ependorff-Heidepriem, Weikun Huang

2023 Diabetes Australia Project Grant (ID: Y23G-RAYN) ($70,000)

Project title: Impact of renal 'sweet taste' sensing on the risk of dysglycaemia.

Chief Investigators: Chris Rayner, Tongzhi Wu, Richard Young, Merlin Thomas, Cong Xie, Weikun Huang

2022 Faculty of Health and Medical Sciences Strategic Research Support, The University of Adelaide ($32,600)

Project title: Application of a novel “organ-on-a-chip” system to understand the role of bitter taste in the regulation of the gut-pancreas axis

Chief Investigators: Tongzhi Wu, Lisa Nicholas, Weikun Huang, Chris Rayner, Heike Ebedorff-Heidepriem

2021 University of Adelaide, Faculty of Health and Medical Sciences - 2021 Small Equipment funding Award – Microfluidic perfusion pump ($2,470).

Tongzhi Wu, Richard Young, Lisa Nicholas, Weikun Huang

Mentoring

Date	Topic	Location	Name
2021 - 2022	Profiling the glucagon-like peptide-1 (GLP-1) secretion from the mouse intestinal tissue ex vivo	The University of Adelaide	Health science undergraduate students

Memberships

Date Role Membership Country

2021 - ongoing Member European Association for the Study of Diabetes Germany

2020 - ongoing Member Australian Diabetes Society Australia

Date	Role	Membership	Country
2021 - ongoing	Member	European Association for the Study of Diabetes	Germany
2020 - ongoing	Member	Australian Diabetes Society	Australia

Email: weikun.huang@adelaide.edu.au

Weikun Huang

Appointments

Awards and Achievements

Language Competencies

Education

Research Interests

Journals

Mentoring

Memberships

Connect With Me

External Profiles