Marianne Chapman

Associate Professor Marianne Chapman

Director of Research

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Professor Marianne Chapman - TITLEHOLDER
Senior Staff Specialist, Intensive Care, Royal Adelaide Hospital.
Clinical Professor, School of Medicine, University of Adelaide.

Professor Chapman is a Senior Staff Specialist in Intensive Care Medicine at the Royal Adelaide Hospital and a Clinical Professor in the School of Medicine at the University of Adelaide.

Her primary degree was from Flinders University of South Australia, graduating in 1982. She trained as an anaesthetist in Plymouth in the UK and worked in Kenya for 12 months before returning to complete intensive care training in Adelaide in 1990. She then spent a further year working in the Hadassah Hospital in Jerusalem in ‘93/94. She has a PhD from the University of Adelaide which involved the investigation of abnormalities in gastrointestinal motility underlying problems with the administration of nutrition to the critically ill.

She has been the Director of Research in the ICU at the Royal Adelaide Hospital since 1998 and is the chairman of the RAH ICU research committee. She was previously a member of the Board of Examiners of the College of Intensive Care Medicine and was involved in a number of other committees including the Formal Project Assessment Panel – College of Intensive Care Medicine, the Abstract Review Committee for the Australian & New Zealand Intensive Care Society, and the Intensive Care Foundation Scientific Committee.

Her clinical research interests include gastrointestinal dysfunction underlying problems with the administration of nutrition, and glucose metabolism in the critically ill. This work is the result of a very successful collaboration with the Departments of Medicine and Gastroenterology in the University of Adelaide, the Royal Adelaide Hospital and the Repatriation General Hospital and forms part of a Centre of Clinical Research Excellence grant from the NH&MRC awarded in 2007.

She currently supervises PhD and honours students undertaking clinical research in the ICU at the Royal Adelaide Hospital. She has published over 100 journal articles, received over $5 million in research funding, and has given invited presentations at national and international meetings.

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  • Appointments

    Date Position Institution name
    2015 Professor University of Adelaide
    2014 Adjunct Associate Professor Monash University
    2008 Professor University of Adelaide
    2004 - 2009 Aeromedical Consultation Royal Adelaide Hospital
    1998 Director of Research Royal Adelaide Hospital
    1994 Senior staff specialist Royal Adelaide Hospital
    1994 - 2015 Consultant/Senior Consultant/Associate Professor Royal Adelaide Hospital
    1994 Visiting ICU Specialist St Andrews Hospital
    1993 - 1994 Consultant Hadassah University Hospital
    1991 - 1993 Intensive Care Trainee and Research Fellow Royal Adelaide Hospital
    1991 Trainee Adelaide Children's Hospital
    1988 - 1989 Intensive Care Trainee The Queen Elizabeth Hospital
    1987 - 1988 Third world medicine/ Anaesthesia Presbyterian Church of East Africa Hospital
    1984 - 1987 Anaesthesia Trainee Plymouth General Hospital
    1983 Resident Medical Officer Queen Elizabeth Hospital & Adelaide Children's Hospital
  • Education

    Date Institution name Country Title
    2010 College of Intensive Care Medicine Australia Fellow of the College of Intensive Care Medicine
    2008 University of Adelaide Australia PhD
    2001 Department of Health Australia Fellow of the Joint Faculty of Intensive Care Medicine
    1993 Australian and New Zealand College of Anaesthetists Australia Fellow of the Faculty of Intensive Care
    1992 Australian and New Zealand College of Anaesthetists Australia Fellow of the Australian and New Zealand College of Anaesthetists
    1990 Royal Australian College of Surgeons (Intensive Care) Australia Fellow of the Faculty of Anaesthetists
    1987 Royal College of Surgeons in Ireland Ireland Fellow of the Faculty of Anaesthetists
    1985 Royal College of Surgeons United Kingdom Diploma of Anaesthesia
    1982 Flinders University Australia Bachelor of Medicine, Bachelor of Surgery
  • Research Interests

Date Project/ No. Investigators Funding Body Amount
2016 Quantification of muscle size and function in response to a randmosied nutritional intervention in critically ill patients.

Costello L-A, Deane AM, Chapman MJ.

Royal Adelaide Hospital Research Trust, Clinical Project Grant $46,198
2016

The effect of protein hydrolysis on the rate and extent of protein absorption and muscle uptake in critically ill patients

Chapman MJ, Deane AM, Soenen S, VanLuc L, Costello L-A Royal Adelaide Hospital Research Trust, Clinical Project Grant $49,560
2015

The effect of critical illness on gallbladder motility, lipid absorption and plasma cholecystokinin concentration

Plummer MP, Deane AM, Chapman MJ, Jones K, Hausken T. Royal Adelaide Hospital Research Trust, Clinical Project Grant $49,565
2015

 

Yandell R, Chapman M.

AUSPEN Research Grant

$30,000
2015

The provision of energy and protein in adults with moderate-severe traumatic brain injury: the relationship between nutrition provision and long-term outcomes.

Costello L, Chapman M AUSPEN Small Research Grant $10,000
2015-2019

The Augmented versus Routine approach to Giving Energy Trial (TARGET)

Chapman M, Peake S, Bellomo R, Horowitz M, Davies A, Deane A. NHMRC Project Grant 1078026 $3,542,500
2014

Title:The effect of routine pantoprazole administration when compared to placebo on gastrointestinal bleeding, ventilator-associated pneumonia and Clostridium difficile infection in enterally-fed mechanically ventilated critically ill patients: A prospective randomised study.

Plummer MP, Deane AM, Chapman MJ, Rayner C. Royal Adelaide Hospital Research Trust, Clinical Project Grant $49,139
2014     Royal Adelaide Hospital. Research Infrastructure Block Grant. $70,000
2014 Gallbladder motility in critical illness.
 
Plummer MP, Deane AM, Chapman MJ, Horowitz M, Jones KL Intensive Care Foundation Trainee Project Grant $5000 
      Royal Adelaide Hospital. Research Infrastructure Block Grant. $70,000
2012-2013

Speech production using a cuffed tracheostomy tube: A comparison of two tracheostomy tube designs

Pryor L, Ward E, Cornwell P, O’Connor S and Chapman M Speech Pathology Australia Post Graduate Research Grant $2,000
2012-2013

Speech production during mechanical ventilation via a cuffed tracheostomy tube: A feasibility study comparing two tracheostomy tube designs.

Pryor L, Ward E, Cornwell P, O’Connor S and Chapman M

Royal Adelaide Hospital Clinical Research Grant for Allied Health-Pharmacy-Nursing

$6,000
2013

Project Title: The Augmented versus Routine approach to Giving Energy Trial (TARGET) in Intensive Care: A feasibility study.

M Chapman, S Peake, A Davies, A Deane ANZCA grant 13/012 $34,300
2012-2017

Centre of Research Excellence in Translating Nutritional Science to Good Health

Horowitz, M, Wittert G, Clifton P, Rayner C, Chapman I, Feinle Bisset C, Jones K, Noakes M, Chapman M, Nguyen N

NHMRC CRE Grant 1041687

$2,499,990
2012-2014

The development of a potent new passive immunotherapeutic for the treatment and prevention of bacterial sepsis and septic shock

Hayball J D, Sproston K, Chapman MJ ARC linkage grant $183,000
2012-2014

Optimising nutrient delivery and absorption in critically ill patients.

Chapman M, Nguyen N, Rayner C, Jones K, Deane A, Horowitz M NHMRC Project Grant APP1025186

$542,500

2011-2012

The effect of nasogastric tubes on swallowing physiology and airway protection in older healthy volunteers

Pryor L, Ward E, Cornwell P, O’Connor S and Chapman M Royal Adelaide Hospital Allied Health Research Grant $5,013
2011

Retrospective review of tracheostomy practices across a tertiary hospital: Is there consistency in management? 

Pryor L, Ward E, Cornwell P, O’Connor S and Chapman M Royal Adelaide Hospital Clinical Research Grant for Allied Health-Pharmacy-Nursing. $15,893 ​​​​​​​
2010

Assessing the neutralising activity of therapeutic antibodies directed against the endogenous alarmin HMGB1 in serum samples from septic shock patients and in an experimental murine model of bacterial sepsis

K Diener, J D Hayball, MJ Chapman RAH Clinical Project Grants $25,000 ​​​​​​​
2010

Effect of critical illness on sweet taste receptors, glucose transporters, glucose absorption and secretion of glucagon-like peptide-1

A Deane, M Chapman Intensive Care Foundation Grant $45,000
2010

Project Title: The Effect of exogenous glucagon-like peptide -1 (GLP-1) on glucose absorption in critically ill patients. 

M Chapman, A Deane ANZCA grant 11/015 $32,517
2008

Additional funding for scintigraphic camera.

Horowitz M, Fraser R, Chapman M. Rayner C, Jones K. Ramaciotti Foundation $30,000
2008

The effects of intravenous sedation on the lower oesophageal sphincter: a comparison between dexmedetomidine and propofol in humans.

Deane A, Bryant L, McConnell H, Holloway R, Chapman M, Fraser R. Royal Adelaide Hospital Special Purposes Fund $21,274
2008

Scintigraphic Camera.

Horowitz M, Fraser R, Chapman M, Rayner C, Jones K. Research Equipment Proposal. Hansen Centre. $100,000
2008-2010

Impact of gastrointestinal dysmotility on enteral nutrition in the critically ill.

Fraser R, Chapman M, Rayner C, Holloway RH, Holtman G, Horowitz M. NHMRC Project Grant $ 618,105
2007

Glucose feedback inhibition of gastroduodenal motility in critical illness.

M Chapman, A Deane, N Nguyen, R Holloway, R Fraser Royal Adelaide Hospital Special Purposes Fund $16,700
2007

Effects of glucagon-like peptide -1 on glucose levels and small intestinal transit in critically ill patients.

M Chapman, R Fraser ANZCA grant 07/032 $40,000
2005-2007

Oesophageal, gastric and small intestinal motility in critical illness.

R Fraser, J Dent, M Horowitz, R Holloway, K Jones, R Young.  Associate Investigator M Chapman NHMRC Grant $491,700
2005

Effect of sedation on upper GI motility, CCK levels & glucose absorption in ICU patients.

  ANZCA grant 05/008 $40,000
2003

Effect of sedation on upper GI motility, CCK levels & glucose absorption in ICU patients.

MJ Chapman, RJL Fraser SPF grant $15,000
2003-2005

Upper Gastrointestinal and absorptive function in critically ill patients.

Fraser, J Dent, M Horowitz, R Holloway, K Jones, R. Young. Associate Investigator M Chapman NHMRC Grant. 207753  $423,984
2002

Motor patterns and gastric emptying in the critically ill. 

M Chapman, Young R, Fraser R, Horowitz M. ANZCA Research Grant 02/002 $15,000
2001

The effect of timing of the initiation of enteral feeding on gastric emptying and glucose absorption in critically ill patients.

M Chapman, D Bartholomeusz, R Fraser, M Horowitz, K Jones, R Young Royal Adelaide Hospital Research Project Grant $15,000
1993

Attenuation of the pathophysiological effects of cerebral arterial gas embolism by reduction of endothelial-leukocyte adhesiveness using a monoclonal antibody to CD11/18.

M Chapman, S Helps Special Purposes Fund, Royal Adelaide Hospital $32,174
1991-1993

Mechanisms of decrement in brain blood flow and function after air embolism.

  NH&MRC Medical Postgraduate Research Scholarship $22,000 per year
1991

Effect of monoclonal antibody to ELAM-1 on the decrement in cerebral blood flow and function observed after cerebral embolism.

  Royal Adelaide Hospital, Special Purposes Fund, Career Development Grant $9700
ASSESSOR FOR HONOURS THESES

University of Adelaide 2012

UNDERGRADUATE EXAMINER

MBBS, University of Adelaide 2012

PARTICIPATION AS A TEACHER IN TRAINING COURSES

1998 – current (Annual)      The Adelaide Intensive Care Short Course (Tub’s Course)

2013                                      The Canberra ICU Course

 

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  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2018 Principal Supervisor Factors Affecting Nutrient Absorption and Gastric Emptying in Health and Illness Doctor of Philosophy Doctorate Full Time Dr Tejaswini Arunachala Murthy
    2017 Co-Supervisor Objective Measurement of Physical Function before and after Critical Illness Doctor of Philosophy Doctorate Full Time Dr Samuel Gluck
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2016 - 2017 Co-Supervisor Feeding the Critically Ill Obese Patient Master of Clinical Science Master Part Time Mr Paul John Secombe
    2014 - 2017 Principal Supervisor Nutrition in Survivors of Critical Illness: An exploration of the effect of nutrition therapy on muscle mass, nutritional status and clinical outcomes after critical illness with a focus on patients with a traumatic brain injury Doctor of Philosophy Doctorate Full Time Ms Lee-anne Chapple
    2013 - 2016 Co-Supervisor Glycaemia and upper gastrointestinal function in health and critical illness Doctor of Philosophy Doctorate Full Time Dr Mark Plummer
    2010 - 2015 Co-Supervisor Tri-iodothyronine (T3) Therapy in a Pre-Clinical Model of Septic Shock Doctor of Philosophy Doctorate Full Time Dr Matthew Jerome Maiden
    2007 - 2012 Co-Supervisor Glucose Metabolism in the Critically Ill Doctor of Philosophy Doctorate Full Time Dr Adam Deane
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  • Committee Memberships

    Date Role Committee Institution Country
    2015 - ongoing Member Level E Title holders promotion committee University of Adelaide Australia
    2010 - ongoing Member Research Committee Royal Adelaide Hospital Australia
    2008 - 2011 Member Scientific Committee Intensive Care Foundation Australia
    2007 - 2011 Member Abstract Review Committee Australian & New Zealand Intensive Care Society Australia
    1999 - 2002 Treasurer Australian and New Zealand Intensive Care Society Clinical Trials Group Australia
    1999 - 2001 Member Clinical Practice Committee Royal Adelaide Hospital Australia
    1998 - 2006 Member Research Ethics Committee Royal Adelaide Hospital Australia
    1998 - ongoing Chair ICU Research Committee Royal Adelaide Hospital Australia
    1995 - 1999 Member Drug Committee Royal Adelaide Hospital Australia

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