Ryan Jalleh
Adelaide Medical School
Faculty of Health and Medical Sciences
Dr Jalleh is an endocrinologist and early career clinician-scientist. He graduated (MBBS) from the University of Adelaide as the top graduate of his year, and was awarded the prestigious Everard Prize for the highest overall grade in medical school (2013), the University Medal (2014) for outstanding academic merit and the Top Scholar Award (2012) for outstanding performance in Obstetrics and Gynaecology. His PhD, focused on the relationship of gastric emptying with glucoregulatory responses and incretin physiology, conducted in the CRE in Translating Nutritional Science into Good Health, was highly productive with 17 publications in major subspecialty journals (first author in 15). His thesis was accepted in Jan 2024 and he was awarded both the Dean’s Commendation for Doctoral Thesis Excellence and the University Doctoral Research Medal from the University of Adelaide.
The theme of his research continues to be the relationships of gastric emptying with glucoregulatory responses and incretin physiology. He has presented his research at numerous international conferences including the European Association for the Study of Diabetes Meetings (EASD) in Barcelona (2019), Stockholm (2022) and Madrid (2024). He was a finalist in the Young Investigator’s Award at the Australasian Diabetes Congress in 2021 and was awarded a prestigious three-year Mary Overton Research Fellowship by the Royal Adelaide Hospital in Dec 2023. Dr Jalleh’s work has had a substantial impact on clinical practice and was recently cited in Australia’s consensus clinical practice recommendations (April 2025) endorsed by the Australian Diabetes Society (ADS), National Association of Clinical Obesity Services, Gastroenterological Society of Australia and Australian and New Zealand College of Anaesthetists regarding consumers taking GLP-1 receptor agonists. He continues ongoing collaborative work with esteemed international experts in gastric emptying and incretin physiology including Professor Michael Nauck, Professor Michael Camilleri and Professor Trygve Hausken.
Dr Jalleh has also been a strong advocate for research and is a member of the Australasian Diabetes Society Research Advisory Committee (since 2022). He has been working with the team to develop a National Diabetes Research Strategy. In addition, he has been part of the steering committee to organise the Adelaide Scientific Exchange Meeting 2024 to disseminate recent knowledge to fellow clinicians and is the convenor for the Adelaide Clinical Endocrine Society meetings. He has participated as a judge for the Australasian Diabetes Congress Quality in Diabetes Care Symposium in 2023 and 2024, and is now convening this initiative in 2025. He is regularly and increasingly invited to peer review journal articles regarding GLP-1 based therapies or incretin physiology and participates actively in this. This has included invitations to review by premier journals such as the Annals of Internal Medicine and The Lancet Diabetes and Endocrinology.
-
Journals
Year Citation 2025 Jalleh, R. J., Plummer, M. P., Marathe, C. S., Umapathysivam, M. M., Quast, D. R., Rayner, C. K., . . . Nauck, M. A. (2025). Clinical Consequences of Delayed Gastric Emptying With GLP-1 Receptor Agonists and Tirzepatide. Journal of Clinical Endocrinology and Metabolism, 110(1), 1-15.
Scopus9 Europe PMC12024 Jalleh, R. J., Jones, K. L., Islam, M. S., Cai, L., & Horowitz, M. (2024). Surgical or medical treatment of obesity-associated type 2 diabetes-an increasing clinical conundrum. World Journal of Diabetes, 15(10), 2036-2040.
2024 Jalleh, R. J., Marathe, C. S., Rayner, C. K., Jones, K. L., Umapathysivam, M. M., Wu, T., . . . Horowitz, M. (2024). Physiology and pharmacology of effects of GLP-1 based therapies on gastric, biliary and intestinal motility. Endocrinology, 166(1), bqae155-1-bqae155-14.
Scopus3 Europe PMC22024 Jalleh, R. J., Phillips, L., Umapathysivam, M. M., Jones, K. L., Marathe, C. S., Watson, L. E., . . . Horowitz, M. (2024). Gastric emptying during and following resolution of moderate diabetic ketoacidosis in type 1 diabetes: a case series. BMJ Open Diabetes Research & Care, 12(2), e003854-1-e003854-4.
Scopus1 Europe PMC12024 Kovoor, J. G., Rayner, C. K., Wu, T., Jalleh, R. J., Maddern, G. J., Horowitz, M., & Jones, K. L. (2024). Effect of lixisenatide on liquid gastric emptying in type 2 diabetes - Implications for the use of GLP-1 receptor agonists before procedures. Journal of Diabetes and Its Complications, 38(8), 108793-1-108793-3.
Scopus5 Europe PMC32024 Smout, A. J. P. M., Jalleh, R. J., Jones, K. L., & Horowitz, M. (2024). Editorial focus: Will the EGG finally hatch?. American Journal of Physiology: Gastrointestinal and Liver Physiology, 327(3), G379-G381.
Scopus12024 Jalleh, R. J., Rayner, C. K., Hausken, T., Jones, K. L., Camilleri, M., & Horowitz, M. (2024). Gastrointestinal effects of GLP-1 receptor agonists: mechanisms, management, and future directions. Lancet Gastroenterology and Hepatology, 9(10), 957-964.
Scopus22 Europe PMC152024 Huang, W. -K., Jalleh, R. J., Rayner, C. K., & Wu, T. -Z. (2024). Management of gestational diabetes mellitus <i>via</i> nutritional interventions: The relevance of gastric emptying. WORLD JOURNAL OF DIABETES, 15(7), 5 pages.
2023 Jalleh, R. J., Umapathysivam, M. M., Plummer, M. P., Deane, A., Jones, K. L., & Horowitz, M. (2023). Postprandial plasma GLP-1 levels are elevated in individuals with postprandial hypoglycaemia following Roux-en-Y gastric bypass – a systematic review. Reviews in Endocrine and Metabolic Disorders, 24(6), 1075-1088.
Scopus8 Europe PMC92023 Jalleh, R. J., Marathe, C. S., Trahair, L. G., Jones, K. L., & Horowitz, M. (2023). A Biphasic Glucose Response during an Oral Glucose Tolerance Test Is Associated with Greater Plasma Insulin and GLP-1 Responses and a Reduction in 1-Hour Glucose but Does Not Relate to the Rate of Gastric Emptying in Healthy, Older Adults. Nutrients, 15(18), 3889-1-3889-9.
Scopus3 Europe PMC22023 Jalleh, R. J., Jones, K. L., Nauck, M., & Horowitz, M. (2023). Accurate Measurements of Gastric Emptying and Gastrointestinal Symptoms in the Evaluation of Glucagon-like Peptide-1 Receptor Agonists. Annals of Internal Medicine, 176(11), 1542-1544.
Scopus9 Europe PMC82023 Xie, C., Jalleh, R. J., Watson, L. E., Huang, W., Sun, Y., Jones, K. L., . . . Wu, T. (2023). Determinants of blood glucose concentrations following a high carbohydrate meal in type 2 diabetes: A multiple linear regression analysis. Diabetes Research and Clinical Practice, 198, 110606.
Scopus6 Europe PMC52023 Jalleh, R. J., Trahair, L. G., Wu, T., Standfield, S., Feinle-Bisset, C., Rayner, C. K., . . . Jones, K. L. (2023). Effect of gastric distension with concurrent small intestinal saline or glucose infusion on incretin hormone secretion in healthy individuals - a randomised, controlled, cross-over study.. Diabetes, obesity & metabolism, 25(7), 1849-1854.
Scopus2 Europe PMC12022 Jalleh, R. J., Rayner, C. K., Jones, K. L., & Horowitz, M. (2022). Glucagon-like peptide-1 receptor agonists, weight loss, and gastric emptying: have I gut news for you. Obesity, 30(8), 1533-1534.
Scopus8 Europe PMC52022 Jalleh, R. J., Rayner, C. K., Jones, K. L., & Horowitz, M. (2022). Isseki nichō (one stone, two birds): a dual incretin receptor agonist for type 2 diabetes.. The lancet. Diabetes & endocrinology, 10(9), S2213-8587(22)00193-0.
Scopus12022 Jalleh, R. J., Xie, C., Deane, A. M., Plummer, M. P., Jones, K. L., Horowitz, M., & Kar, P. (2022). One-hour plasma glucose level after a 75 g oral glucose load and its relationship to gastric emptying in survivors of critical illness and stress hyperglycaemia. Critical Care and Resuscitation, 24(3), 268-271.
Scopus2 Europe PMC12022 Jalleh, R. J., Jones, K. L., Rayner, C. K., Marathe, C. S., Wu, T., & Horowitz, M. (2022). Normal and disordered gastric emptying in diabetes: recent insights into (patho)physiology, management and impact on glycaemic control.. Diabetologia, 65(12), 1981-1993.
Scopus56 WoS19 Europe PMC322022 Stevens, J. E., Jalleh, R. J., Trahair, L. G., Marathe, C. S., Horowitz, M., & Jones, K. L. (2022). Comparative effects of low-carbohydrate, full-strength and low-alcohol beer on gastric emptying, alcohol absorption, glycemia and insulinemia in health. British Journal of Clinical Pharmacology, 88(7), 3421-3427.
Scopus1 Europe PMC32022 Jalleh, R. J., Wu, T., Jones, K. L., Rayner, C. K., Horowitz, M., & Marathe, C. S. (2022). Relationships of glucose, GLP-1 and insulin secretion with gastric emptying after a 75g glucose load in type 2 diabetes.. J Clin Endocrinol Metab, 107(9), e3850-e3856.
Scopus12 WoS5 Europe PMC92021 Jalleh, R., & Torpy, D. J. (2021). The Emerging Role of Copeptin.. The Clinical biochemist. Reviews, 42(1), 17-25.
Europe PMC182021 Jalleh, R. J., Marathe, C. S., Jones, K. L., Horowitz, M., & Rayner, C. K. (2021). Digesting the pathogenesis of diabetic gastroparesis. Journal of Diabetes and its Complications, 35(10), 3 pages.
Scopus5 WoS1 Europe PMC22020 Jalleh, R., Pham, H., Marathe, C. S., Wu, T., Buttfield, M. D., Hatzinikolas, S., . . . Jones, K. L. (2020). Acute Effects of Lixisenatide on Energy Intake in Healthy Subjects and Patients with Type 2 Diabetes: Relationship to Gastric Emptying and Intragastric Distribution.. Nutrients, 12(7), 1-8.
Scopus22 WoS12 Europe PMC142019 Jalleh, R., Marathe, C. S., Rayner, C. K., Jones, K. L., & Horowitz, M. (2019). Diabetic Gastroparesis and Glycaemic Control.. Curr Diab Rep, 19(12), 153.
Scopus20 WoS14 Europe PMC212018 Jalleh, R., Basu, G., Le Leu, R., & Jesudason, S. (2018). Denosumab-Induced Severe Hypocalcaemia in Chronic Kidney Disease.. Case reports in nephrology, 2018, 7384763.
Europe PMC172014 Sannarangappa, V., & Jalleh, R. (2014). Inhaled corticosteroids and secondary adrenal insufficiency. Open Respiratory Medicine Journal, 8(1), 93-100.
Scopus37 Europe PMC242012 Jalleh, R., Koh, K., Choi, B., Liu, E., Maddison, J., & Hutchinson, M. (2012). Role of microglia and toll-like receptor 4 in the pathophysiology of delirium. Medical Hypotheses, 79(6), 735-739.
Scopus22 WoS17 Europe PMC15 -
Conference Papers
Year Citation 2023 Marathe, J. A., Kamruzzaman, M., Jalleh, R. J., Horowitz, M., Jones, K. L., & Marathe, C. S. (2023). Diabetes distress and depression frequently co-exist in people with type 2 diabetes in Bangladesh. In DIABETOLOGIA Vol. 66 (pp. S446-S447). GERMANY, Hamburg: SPRINGER. -
Conference Items
Year Citation 2023 Huynh, L. Q., Hatzinikolas, S., Jalleh, R. J., Marathe, C. S., Wu, T., Malbert, C. -H., . . . Jones, K. L. (2023). Effect of exenatide once-weekly (QW) on the blood pressure and glycaemic responses to a mashed potato meal in type 2 diabetes: relationships to gastric emptying. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2022 Stevens, J. E., Jalleh, R. J., Trahair, L. G., Marathe, C. S., Horowitz, M., & Jones, K. (2022). Comparative effects of low-carbohydrate, full-strength and low-alcohol beer on gastric emptying, alcohol absorption, glycaemia and insulinaemia in health.. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY. 2022 Xie, C., Jalleh, R. J., Huang, W., Sun, Y., Jones, K. L., Horowitz, M., . . . Wu, T. (2022). Determinants of blood glucose concentrations after a high carbohydrate meal in type 2 diabetes: a multiple linear regression analysis. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm & Online: Springer.
DOI2022 Jalleh, R. J., Umapathysivam, M., Louise, J., Plummer, M. P., Deane, A., Jones, K. L., & Horowitz, M. (2022). Incretin hormone and glucoregulatory responses to nutrients in individuals with and without post-bariatric hypoglycaemia: a systematic review. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm & Online: Springer.
DOI2019 Jalleh, R. J., Pham, H. T., Marathe, C. S., Wu, T., Buttfield, M. D., Hatzinikolas, S., . . . Jones, K. L. (2019). Acute effects of lixisenatide on intragastric meal distribution: impact on energy intake. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
Dr Jalleh has been the primary recipient of prestigious research grants and awards including the NHMRC post-graduate scholarship ($132,743), Mary Overton Early Career Fellowship ($321,248) and ADS/RACP Research Establishment Fellowship ($50,000).
Dr Jalleh is a clinical senior lecturer at the University of Adelaide and provide mentorship to the year 3 medical students and organised the year 3 OSCEs in 2024. He also supervises the research projects for Endocrinology Advanced Trainees, with one being selected for oral presentation at the Madrid EASD meeting in 2024.
He was awarded the Australian Medical Students Foundation Intern Teaching Award in 2015.
Connect With Me
External Profiles