Skip to main content

Dr Dan Peet

Dan Peet
Biochemistry and CMGD Lecturer
School of Biological Sciences
Faculty of Sciences

Dr Peet is an Associate Professor in Biochemistry at the University of Adelaide. His research interests are centred on understanding the molecular events within cells that underpin the genomic response to hypoxia. The cellular response to hypoxia is essential for many physiological processes in normal development and adult physiology, and contributes to the pathophysiology of major human diseases, including cancer, myocardial and cerebral ischaemia, pulmonary hypertension, and wound healing. The key components of this cellular response to hypoxia are a unique family of hydroxylase enzymes that act as the primary oxygen sensors, the Hypoxic Inducible transcription Factors (HIFs) that directly regulate gene expression, and specific target genes that mediate cellular changes. His research interests extend beyond the HIFs, to the identification and characterisation of novel substrates of the oxygen-sensing hydroxylases. Understanding these processes has major implications for the diagnosis, prognosis and novel therapeutic approaches to treat human disease.

A more recent focus is on cellular metabolism, specifically the unusual metabolism displayed by proliferating cells, especially cancer cells, that mimic quiescent cells in hypoxia. Of particular interest are the photoreceptor cells in the retina, which also display cancer-like metabolism. A key aim is to determine what controls this unusual metabolism, and whether it is a similar mechanism of control to cancer cells, with important implications for retinal disease.

Connect With Me

External Profiles

Dr Dan Peet

Dr Peet is an Associate Professor in Biochemistry at the University of Adelaide. His research interests are centred on understanding the molecular events within cells that underpin the genomic response to hypoxia. The cellular response to hypoxia is essential for many physiological processes in normal development and adult physiology, and contributes to the pathophysiology of major human diseases, including cancer, myocardial and cerebral ischaemia, pulmonary hypertension, and wound healing. The key components of this cellular response to hypoxia are a unique family of hydroxylase enzymes that act as the primary oxygen sensors, the Hypoxic Inducible transcription Factors (HIFs) that directly regulate gene expression, and specific target genes that mediate cellular changes. His research interests extend beyond the HIFs, to the identification and characterisation of novel substrates of the oxygen-sensing hydroxylases. Understanding these processes has major implications for the diagnosis, prognosis and novel therapeutic approaches to treat human disease.

A more recent focus is on cellular metabolism, specifically the unusual metabolism displayed by proliferating cells, especially cancer cells, that mimic quiescent cells in hypoxia. Of particular interest are the photoreceptor cells in the retina, which also display cancer-like metabolism. A key aim is to determine what controls this unusual metabolism, and whether it is a similar mechanism of control to cancer cells, with important implications for retinal disease.

Eligible to supervise Masters and PhD — email supervisor to discuss availability.

Appointments

Date Position Institution name
2003 Associate Professor University of Adelaide

Education

Date Institution name Country Title
University of Melbourne Australia PhD

Research Interests

Journals

Year Citation
2018 Sim, J., Cowburn, A., Palazon, A., Madhu, B., Tyrakis, P., Macías, D., . . . Johnson, R. (2018). The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia. Cell Metabolism, 27(4), 898-913.e7.
DOI
2017 Vandyke, K., Zeissig, M., Hewett, D., Martin, S., Mrozik, K., Cheong, C., . . . Zannettino, A. (2017). HIF-2α promotes dissemination of plasma cells in multiple myeloma by regulating CXCL12/CXCR4 and CCR1. Cancer Research, 77(20), 5452-5463.
DOI Scopus1 WoS1
2017 Chen, D., Fabrizio, J., Wilkins, S., Dave, K., Gorman, J., Gleadle, J., . . . Mercer, A. (2017). Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.. J Virol, 91(1), e01430-1-e01430-16.
DOI Scopus1 WoS1
2017 Peet, D., Kittipassorn, T., Wood, J., Chidlow, G., & Casson, R. (2017). HIF signalling: the eyes have it. Experimental Cell Research, 356(2), 136-140.
DOI Scopus1 WoS1 Europe PMC1
2017 Nagarajan, Y., Rychkov, G., & Peet, D. (2017). Modulation of TRP channel activity by hydroxylation and its therapeutic potential. Pharmaceuticals, 10(2), 35.
DOI Scopus2 Europe PMC2
2016 Sullivan, A., Peet, D., & Whitelaw, M. (2016). MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors. FEBS Journal, 283(18), 3488-3502.
DOI Scopus1 WoS1
2016 Scholz, C., Rodriguez, J., Pickel, C., Burr, S., Fabrizio, J., Nolan, K., . . . Taylor, C. (2016). FIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1. PLoS Biology, 14(1), e1002347-1-e1002347-22.
DOI Scopus21 WoS18 Europe PMC17
2016 Casson, R., Wood, J., Han, G., Kittipassorn, T., Peet, D., & Chidlow, G. (2016). M-type pyruvate kinase isoforms and lactate dehydrogenase a in the mammalian retina: metabolic implications. Investigative Ophthalmology and Visual Science, 57(1), 66-80.
DOI Scopus14 WoS13 Europe PMC8
2015 Ng, S., Wood, J., Chidlow, G., Han, G., Kittipassorn, T., Peet, D., & Casson, R. (2015). Cancer-like metabolism of the mammalian retina. Clinical and Experimental Ophthalmology, 43(4), 367-376.
DOI Scopus17 WoS16 Europe PMC8
2015 Karttunen, S., Duffield, M., Scrimgeour, N., Squires, L., Lim, W., Dallas, M., . . . Peet, D. (2015). Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel. Journal of Cell Science, 128(2), 225-231.
DOI Scopus13 WoS13 Europe PMC12
2015 Kittipassorn, T., & Peet, D. (2015). Hypoxia inducible factor single nucleotide polymorphisms: exploring the role of HIF polymorphisms in retinal disease. Clinical and Experimental Ophthalmology, 43(1), 1-2.
DOI
2015 Kind, K., Tam, K., Banwell, K., Gauld, A., Russell, D., Macpherson, A., . . . Thompson, J. (2015). Oxygen-regulated gene expression in murine cumulus cells. Reproduction, Fertility and Development, 27(2), 407-418.
DOI Scopus2 WoS2 Europe PMC1
2015 Ng, S., Wood, J., Chidlow, G., Peet, D., & Casson, R. (2015). Potential adverse effects to the retina of cancer therapy targeting pyruvate kinase M2. Acta Oncologica, 54(1), 136-137.
DOI Scopus1 WoS1
2014 Sullivan, A., Raimondo, A., Schwab, T., Bruning, J., Froguel, P., Farooqi, I., . . . Whitelaw, M. (2014). Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2. Biochemical Journal, 461(3), 403-412.
DOI Scopus5 WoS4 Europe PMC4
2014 Bersten, D., Bruning, J., Peet, D., & Whitelaw, M. (2014). Human variants in the Neuronal Basic Helix-Loop-Helix/ Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function. PLoS One, 9(1), e85768-1-e85768-11.
DOI Scopus10 WoS10 Europe PMC10
2013 Bersten, D., Sullivan, A., Peet, D., & Whitelaw, M. (2013). BHLH-PAS proteins in cancer. Nature Reviews. Cancer, 13(12), 827-841.
DOI Scopus65 WoS59 Europe PMC58
2013 Bonnefond, A., Raimondo, A., Stutzmann, F., Ghoussaini, M., Ramachandrappa, S., Bersten, D., . . . Froguel, P. (2013). Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features. Journal of Clinical Investigation, 123(7), 3037-3041.
DOI Scopus40 WoS40 Europe PMC32
2013 Ramachandrappa, S., Raimondo, A., Cali, A., Keogh, J., Henning, E., Saeed, S., . . . Farooqi, I. (2013). Rare variants in single-minded 1 (SIM1) are associated with severe obesity. Journal of Clinical Investigation, 123(7), 3042-3050.
DOI Scopus56 WoS51 Europe PMC42
2013 Hao, N., Bhakti, V., Peet, D., & Whitelaw, M. (2013). Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation. Nucleic Acids Research, 41(11), 5626-5638.
DOI Scopus12 WoS12 Europe PMC11
2013 Ramachandrappa, S., Raimondo, A., Cali, A., Keogh, J., Henning, E., Saeed, S., . . . Farooqi, I. (2013). Erratum: Rare variants in single-minded 1 (SIM1) are associated with severe obesity (Journal of Clinical Investigation (2013) 123:7 (3042-3050) DOI: 10.1172/JCI68016). Journal of Clinical Investigation, 123(8), 3635.
DOI
2012 Wilkins, S., Karttunen, S., Hampton-Smith, R., Murchland, I., Chapman-Smith, A., & Peet, D. (2012). Factor Inhibiting HIF (FIH) recognizes distinct molecular features within hypoxia-inducible factor-α (HIF-α) versus ankyrin repeat substrates. Journal of Biological Chemistry, 287(12), 8769-8781.
DOI Scopus19 WoS19 Europe PMC16
2012 Olechnowicz, S., Fedele, A., & Peet, D. (2012). Hypoxic induction of the regulator of G-protein signalling 4 gene is mediated by the hypoxia-inducible factor pathway. PLoS One, 7(9), 1-12.
DOI Scopus7 WoS7 Europe PMC4
2012 Yusuf, D., Olechnowicz, S., & Peet, D. (2012). The Transcription factor encyclopedia. Genome Biology, 13(3), R24:1-R24:25.
DOI Scopus50 WoS47 Europe PMC46
2011 Martin, S., Diamond, P., Gronthos, S., Peet, D., & Zannettino, A. (2011). The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma. Leukemia, 25(10), 1533-1542.
DOI Scopus65 WoS63 Europe PMC57
2010 Devries, I., Hampton-Smith, R., Mulvihill, M., Alverdi, V., Peet, D., & Komives, E. (2010). Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH). FEBS Letters, 584(23), 4725-4730.
DOI Scopus14 WoS14 Europe PMC10
2010 Tam, K., Russell, D., Peet, D., Bracken, C., Rodgers, R., Thompson, J., & Kind, K. (2010). Hormonally regulated follicle differentiation and luteinization in the mouse is associated with hypoxia inducible factor activity. Molecular and Cellular Endocrinology, 327(1-2), 47-55.
DOI Scopus22 WoS21 Europe PMC17
2010 Martin, S., Diamond, P., Williams, S., To, L., Peet, D., Fujii, N., . . . Zannettino, A. (2010). Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells. Haematologica, 95(5), 776-784.
DOI Scopus52 WoS47 Europe PMC37
2010 Zhang, N., Fu, Z., Karttunen, S., Chicher, J., Gorman, J., Visk, D., . . . Johnson, R. (2010). The asparaginyl hydroxylase factor inhibiting HIF-1α is an essential regulator of metabolism. Cell Metabolism, 11(5), 364-378.
DOI Scopus95 WoS96 Europe PMC82
2009 Hampton-Smith, R., & Peet, D. (2009). From polyps to people: A HIghly Familiar response to hypoxia. Annals of the New York Academy of Sciences, 1177(1), 19-29.
DOI Scopus27 WoS24 Europe PMC21
2009 Wilkins, S., Hyvarinen, J., Chicher, J., Gorman, J., Peet, D., Bilton, R., & Koivunen, P. (2009). Differences in hydroxylation and binding of Notch and HIF-1 alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1). International Journal of Biochemistry & Cell Biology, 41(7), 1563-1571.
DOI Scopus39 WoS33 Europe PMC28
2008 Lisy, K., & Peet, D. (2008). Turn me on: regulating HIF transcriptional activity. Cell Death and Differentiation, 15(4), 642-649.
DOI Scopus115 WoS110 Europe PMC80
2008 Zheng, X., Karttunen, S., Dias, J., Zheng, X., Gradin, K., Wallis, T., . . . Poellinger, L. (2008). Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proceedings of the National Academy of Sciences of the United States of America, 105(9), 3368-3373.
DOI Scopus152 WoS155 Europe PMC122
2008 Lisy, K., & Peet, D. (2008). Erratum: Turn me on: Regulating HIF transcriptional activity (Cell Death and Differentiation (2008) 10.1038/sj.cdd.4402315). Cell Death and Differentiation, 15(4), 805.
DOI
2007 Gorman, J., Wallis, T., Dave, K., Hamilton, B., Headlam, M., Linke, S., & Peet, D. (2007). Quantitative approaches for analysis of regulatory post-translational modifications. MOLECULAR & CELLULAR PROTEOMICS, 6(8), 15.
2007 Karttunen, S., Hampton-Smith, R., & Peet, D. (2007). Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor. Methods in Enzymology, 435, 61-85.
DOI Scopus20 WoS20 Europe PMC17
2006 Bracken, C., Fedele, A., Karttunen, S., Balrak, W., Lisy, K., Whitelaw, M., & Peet, D. (2006). Cell-specific regulation of hypoxia-inducible factor (HIF)-1α and HIF-2α stabilization and transactivation in a graded oxygen environment. Journal of Biological Chemistry, 281(32), 22575-22585.
DOI Scopus103 WoS99 Europe PMC78
2005 Bracken, C., Whitelaw, M., & Peet, D. (2005). Activity of hypoxia-inducible factor 2α is regulated by association with the NF-κB essential modulator. Journal of Biological Chemistry, 280(14), 14240-14251.
DOI Scopus50 WoS49 Europe PMC41
2004 Peet, D., Lando, D., Whelan, D., Whitelaw, M., & Gorman, J. (2004). Oxygen-dependent asparagine hydroxylation. Methods in Enzymology, 381, 467-487.
DOI Scopus18 WoS14 Europe PMC8
2004 Karttunen, S., Stojkoski, C., Kewley, R., Booker, G., Whitelaw, M., & Peet, D. (2004). Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor. Biological Chemistry, 279(14), 14391-14397.
DOI Scopus62 WoS57 Europe PMC37
2003 Bracken, C., Whitelaw, M., & Peet, D. (2003). The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses. Cellular and Molecular Life Sciences, 60(7), 1376-1393.
DOI Scopus161 WoS149 Europe PMC115
2003 Lees, M., Peet, D., & Whitelaw, M. (2003). Defining the role for XAP2 in stabilization of the dioxin receptor. Journal of Biological Chemistry, 278(38), 35878-35888.
DOI Scopus60 WoS51 Europe PMC26
2003 Lando, D., Gorman, J., Whitelaw, M., & Peet, D. (2003). Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation. FEBS Journal, 270(5), 781-790.
DOI Scopus98 WoS88 Europe PMC57
2002 Fedele, A., Whitelaw, M., & Peet, D. (2002). Regulation of gene expression by the hypoxia-inducible factors. Molecular Interventions, 2(4), 229-243.
DOI Scopus58 Europe PMC36
2002 Lando, D., Peet, D., Pongratz, I., & Whitelaw, M. (2002). Mammalian two-hybrid assay showing redox control of HIF-like factor. Methods in Enzymology, 353, 3-10.
DOI Scopus3 WoS3 Europe PMC1
2002 Lando, D., Peet, D., Gorman, J., Whelan, D., Whitelaw, M., & Bruick, R. (2002). FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes & Development, 16(12), 1466-1471.
DOI Scopus945 WoS909 Europe PMC671
2002 Lando, D., Peet, D., Whelan, D., Gorman, J., & Whitelaw, M. (2002). Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch. Science, 295(5556), 858-861.
DOI Scopus1075 WoS1013 Europe PMC680
1998 Peet, D., Janowski, B., & Mangelsdorf, D. (1998). The LXRs: A new class of oxysterol receptors. Current Opinion in Genetics and Development, 8(5), 571-575.
DOI Scopus277 WoS262 Europe PMC166
1998 Peet, D., Turley, S., Ma, W., Janowski, B., Lobaccaro, J., Hammer, R., & Mangelsdorf, D. (1998). Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα. Cell, 93(5), 693-704.
DOI Scopus1047 WoS1027 Europe PMC668
1998 Peet, D., Doyle, D., Corey, D., & Mangelsdorf, D. (1998). Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR. Chemistry and Biology, 5(1), 13-21.
DOI Scopus42 WoS40 Europe PMC26
1998 Corey, D., Doyle, D., Peet, D., & Mangelsdorf, D. (1998). Engineering novel specificities for ligand dependent transcriptional activation. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 216, U256.
1998 Doyle, D., Peet, D., Mangelsdorf, D., & Corey, D. (1998). Changing the ligand-binding specificity of the nuclear hormone receptor RXR.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 215, U876.
1996 Jones, L., Peet, D., Danks, D., Negri, A., & Rivett, D. (1996). Hairs from patients with maple syrup urine disease show a structural defect in the fiber cuticle. Journal of Investigative Dermatology, 106(3), 461-464.
DOI Scopus28 Europe PMC12
1996 Negri, A., Peet, D., Rivett, D., Rivett, R., & Cornell, H. (1996). Covalently Bound Fatty Acids and Ceramides in Wool. Journal of the Textile Institute, 87(3), 608-611.
DOI
1995 Peet, D., Rivett, D., & Wettenhall, R. (1995). The Chemistry of the Cuticle Surface of Keratin Fibers. Textile Research Journal, 65(1), 58-59.
DOI Scopus20 WoS18
1992 Peet, D., Wettenhall, R., Rivett, D., & Allen, A. (1992). A comparative study of covalently-bound fatty acids in keratinized tissues. Comparative Biochemistry and Physiology -- Part B: Biochemistry and, 102(2), 363-366.
DOI Scopus20 WoS19 Europe PMC3

Book Chapters

Conference Papers

Year Citation
2006 Murphy, M., Schumacker, P., Kummer, W., Archer, S., Harris, A., Sylvester, J., . . . Peet, D. (2006). Discussion. In Novartis Foundation Symposium Vol. 272 (pp. 192-195).
2006 Duchen, M., Semenza, G., Ratcliffe, P., López-Barneo, J., Prabhakar, N., Acker, H., . . . Archer, S. (2006). Discussion. In Novartis Foundation Symposium Vol. 272 (pp. 8-14).
2006 Ratcliffe, P., Peet, D., Chandel, N., Semenza, G., Stolze, I., Pouysségur, J., . . . Schumacker, P. (2006). Discussion. In Novartis Foundation Symposium Vol. 272 (pp. 49-53).
2005 Peet, D. (2005). Cellular response to hypoxia: A key role for oxygen-sensing peptidyl hydroxylases. In JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 39 (pp. 568-569). Perth, AUSTRALIA: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD.
1999 Rivett, D., & Peet, D. (1999). Fatty acids chemically bound to protein forms the hydrophic membrane of the hair cuticle. In Experimental Dermatology Vol. 8 (pp. 360-361). Denmark.

Conference Items

Year Citation
2016 Scholz, C., Rodriguez, J., Pickel, C., Burr, S., Fabrizio, J. -A., Nolan, K., . . . Taylor, C. (2016). FIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1. Poster session presented at the meeting of ACTA PHYSIOLOGICA. WILEY-BLACKWELL.
2009 Lisy, K., & Peet, D. J. (2009). Is FIH-1 Phosphorylated? 2-DE Analysis of FIH-1 Isoforms. Poster session presented at the meeting of Hypoxia and Consequences: From Molecule to Malady. New York, New York.
2007 Lisy, K., & Peet, D. J. (2007). Regulation of Gene Expression via the Asparaginyl Hydroxylase Factor Inhibiting HIF (FIH-1). Poster session presented at the meeting of Lorne Cancer Conference. Lorne, Australia.
2006 Lisy, K., & Peet, D. J. (2006). Characterising Expression of the Asparaginyl Hydroxylase Factor Inhibiting HIF (FIH-1). Poster session presented at the meeting of Lorne Genome Conference. Lorne, Australia.
2005 Lisy, K., & Peet, D. J. (2005). Characterisation of FIH-1 Expression. Poster session presented at the meeting of Australian Society for Biochemistry and Molecular Biology ComBio Conference. Adelaide, Australia.

Patents

Current Higher Degree by Research Supervision (University of Adelaide)

Date Role Research Topic Program Degree Type Student Load Student Name
2017 Principal Supervisor Elucidating the Roles HIFI/HIFI2 on Multiple Myeloma Using an Inducible CRISPR/Cas9 System Master of Philosophy Master Full Time Mr Yu Chinn Joshua Chey
2017 Co-Supervisor Characterising the Proteom of Invasive and Metastatic Ovarian Cancer Cells Doctor of Philosophy Doctorate Full Time Mitchell Aidan Acland
2017 Principal Supervisor Role of Hypoxic Inducible Factors in Retinal Metabolism Doctor of Philosophy Doctorate Full Time Mr Cameron David Haydinger
2015 Co-Supervisor Structure and Function of Basic Helix-Loop-Helix/Pas Transcription Factors Doctor of Philosophy Doctorate Full Time Miss Alexis Georgia Gerassimou
2014 Principal Supervisor Molecular Mechanisms for the Warburg Effect in the Mammalian Retina Doctor of Philosophy Doctorate Full Time Miss Thaksaon Kittipassorn
2011 Principal Supervisor Differential Regulation of the Hypoxia Inducible Transcription Factors HIF-1x and HIF-2x Doctor of Philosophy Doctorate Full Time Miss Natalia Magdalena Martin

Past Higher Degree by Research Supervision (University of Adelaide)

Date Role Research Topic Program Degree Type Student Load Student Name
2013 - 2018 Principal Supervisor Characterising Novel Substrates of the Asparaginyl Hydroxylase FIH Doctor of Philosophy Doctorate Full Time Miss Jacqueline-Alba Fabrizio
2012 - 2018 Co-Supervisor Regulation of Sphingosine Kinase 1 Oncogenic Signalling by Calcium and Integrin Binding Proteins Doctor of Philosophy Doctorate Part Time Ms Wenying Zhu
2009 - 2016 Co-Supervisor Function and Regulation of Single-minded 1 and Single-minded 2 Transcription Factors in Disease Doctor of Philosophy Doctorate Full Time Ms Adrienne Sullivan
2007 - 2012 Principal Supervisor Characterising Ankyrin Repeat Proteins as Substrates of the Asparaginyl Hydroxylase FIH Doctor of Philosophy Doctorate Full Time Miss Sarah Wilkins
2006 - 2012 Principal Supervisor Regulation of the Rgs4 Gene by the Hypoxia Inducible Factors Doctor of Philosophy Doctorate Full Time Mr Sam Olechnowicz
2006 - 2014 Co-Supervisor Regulation of Expression and Activity of the bHLH-PAS Transcription Factor NPAS4 Doctor of Philosophy Doctorate Full Time Dr David Bersten
2005 - 2011 Principal Supervisor Investigating Potential Post-Translational Modification of Factor-Inhibiting HIF (FIH-1) Doctor of Philosophy Doctorate Full Time Ms Karolina Lisy
2005 - 2016 Principal Supervisor Identification and Characterisation of Novel Substrates and Binding Partners of the Asparaginyl Hydroxylase, FIH Doctor of Philosophy Doctorate Part Time Ms Rachel Hampton-Smith
2004 - 2008 Principal Supervisor Substrate Specificity of Factor Inhibiting HIF-1 (FIH-1) Doctor of Philosophy Doctorate Full Time Dr Sarah Karttunen
2004 - 2009 Co-Supervisor Gene Regulatory and Pro-Tumourigenic Mechanisms of the bHLH-PAS Transcription Factor SIM2s Doctor of Philosophy Doctorate Full Time Ms Alexandra Farrall
2003 - 2005 Co-Supervisor Differential Function and Regulation of the Hypoxia Inducible Factors in the Rat Pheochromocytoma Cell Line Pc12 Doctor of Philosophy Doctorate Full Time Mr Anthony Fedele
2001 - 2005 Co-Supervisor Characterising the Differential Regulation of Hypoxia-Inducible Factor 1a and 2a Doctor of Philosophy Doctorate Full Time Mr Cameron Bracken

Memberships

Date Role Membership Country
2009 - 2011 Member New York Academy of Sciences
2004 - ongoing Member American Society of Biochemistry and Molecular Biology United States
2004 - ongoing Member Federation of American Societies for Experimental Biology United States
1990 - ongoing Member Australian Society of Biochemistry and Molecular Biology Australia

Editorial Boards

Date Role Editorial Board Name Institution Country
2015 - ongoing Consulting Editor Journal of Hypoxia University of Adelaide Australia
Position
Biochemistry and CMGD Lecturer
Phone
83135367
Fax
8313 4362
Campus
North Terrace
Building
Molecular Life Sciences, floor 3
Room Number
3 40
Org Unit
Molecular and Cellular Biology

top