Dr Yu Chinn Joshua Chey

• Appointments

  Date	Position	Institution name
  2024 - ongoing	Postdoctoral Researcher	SAiGENCI
  2024 - 2024	Research Officer	University of Adelaide

• Awards and Achievements

  Date	Type	Title	Institution Name	Country	Amount
  2020	Scholarship	Adelaide Graduate Research Scholarship	The University of Adelaide	Australia	-
  2018	Award	Most Outstanding Student Poster: Runner Up	Australia and New Zeland Society for Cell and Developmental Biology Inc.	Australia	-
  2017	Scholarship	Master of Philosophy International Scholarship 2017	The University of Adelaide	Australia	-
  2017	Award	The RA Fisher Prize for Genetics II 2016	The University of Adelaide	Australia	-
  2015	Scholarship	Adelaide Summer Research Scholarship 2015	The University of Adelaide	Australia	-
  2014	Award	Outstanding Academic Achievement Award 2014, 2015, 2016, 2017	The University of Adelaide	Australia	-

• Language Competencies

  Language	Competency
  English	Can read, write, speak, understand spoken and peer review
  Malay	Can read, write, speak and understand spoken

• Education

  Date	Institution name	Country	Title
  2020 - 2024	University of Adelaide	Australia	Doctor of Philosophy
  2017 - 2020	University of Adelaide, Adelaide	Australia	Master of Philosophy
  2014 - 2017	University of Adelaide, Adelaide	Australia	Bachelor of Science (Biomedical Science)

• Research Interests

  Biochemistry & Molecular Biology Biochemistry and Cell Biology Biological Sciences Cancer Cell Biology Cell Biology Gene and Molecular Therapy Genetics Medical and Health Sciences Innovative Therapeutics Musculoskeletal Health Translational Health Outcomes Cancer Biology and Clinical Oncology Immunology and Infection Biomarkers

• Journals

  Year	Citation
  2025	Chey, Y. C. J., Gierus, L., Lushington, C., Arudkumar, J. C., B Geiger, A., Staker, L. G., . . . Thomas, P. Q. (2025). Optimal SpCas9- and SaCas9-mediated gene editing by enhancing gRNA transcript levels through scaffold poly-T tract reduction. . BMC genomics, 26(1), 138. DOI
  2024	Chey, Y. C. J., Corbett, M. A., Arudkumar, J., Piltz, S. G., Thomas, P. Q., & Adikusuma, F. (2024). CRISPR-mediated megabase-scale transgene de-duplication to generate a functional single-copy full-length humanized DMD mouse model. BMC Biology, 22(1), 15 pages. DOI
  2023	Chey, Y. C. J., Arudkumar, J., Aartsma‐Rus, A., Adikusuma, F., & Thomas, P. Q. (2023). CRISPR applications for Duchenne muscular dystrophy: From animal models to potential therapies. WIREs Mechanisms of Disease, 15(1), e1580-1-e1580-26. DOI Scopus10 WoS4 Europe PMC9
  2021	Adikusuma, F., Lushington, C., Arudkumar, J., Godahewa, G. I., Chey, Y. C. J., Gierus, L., . . . Thomas, P. Q. (2021). Optimized nickase- and nuclease-based prime editing in human and mouse cells. Nucleic Acids Research, 49(18), 10785-10795. DOI Scopus48 WoS26 Europe PMC27
  2018	Sim, J., Cowburn, A. S., Palazon, A., Madhu, B., Tyrakis, P. A., Macias, D., . . . Johnson, R. S. (2018). The Factor Inhibiting HIF asparaginyl hydroxylase regulates oxidative metabolism and accelerates metabolic adaptation to hypoxia. Cell Metabolism, 27(4), 898-e.7. DOI Scopus62 WoS45 Europe PMC38
  -	Arudkumar, J., Chey, Y. C. J., Piltz, S. G., Thomas, P. Q., & Adikusuma, F. (n.d.). CRISPR-mediated generation and comprehensive phenotyping of Duchenne Muscular Dystrophy mouse models. BMC Methods, 1(1). DOI

• Theses

  Year	Citation
  2019	Chey, Y. C. (2019). Generation and Transcriptomic Analysis of HIF-1Alpha and HIF-2Alpha Knockout 5TGM1 Multiple Myeloma Cells. (Master's Thesis).

• Preprint

  Year	Citation
  2024	Chey, Y., Corbett, M., Arudkumar, J., Piltz, S., Thomas, P., & Adikusuma, F. (2024). Megabase-Scale Transgene De-Duplication to Generate a Functional Single-Copy Full-Length Human DMD Transgenic Mouse Model. DOI
  2024	Chey, Y., Gierus, L., Lushington, C., Arudkumar, J., Geiger, A., Staker, L., . . . Adikusuma, F. (2024). Enhancing gRNA Transcript levels by Reducing the Scaffold Poly-T Tract for Optimal SpCas9- and SaCas9-mediated Gene Editing. DOI
  2024	Arudkumar, J., Chey, Y. C. J., Piltz, S. G., Thomas, P. Q., & Adikusuma, F. (2024). Generation and characterisation of mouse models of Duchenne Muscular Dystrophy (DMD). DOI
  2021	Adikusuma, F., Lushington, C., Arudkumar, J., Godahewa, G., Chey, Y. C. J., Gierus, L., . . . Thomas, P. (2021). Optimized nickase- and nuclease-based prime editing in human and mouse cells. DOI

2023, 2024 - Guest Lecturer, Biochemistry III: Cancer, Stem Cells and Development

2018, 2019, 2022 - Prac Lab Demonstrator, Biochemistry III: Cancer, Stem Cells and Development

• Committee Memberships

  Date	Role	Committee	Institution	Country
  2022 - 2024	Member	Adelaide Protein Group	Australian Society for Biochemistry and Molecular Biology	Australia

• Memberships

  Date	Role	Membership	Country
  2021 - 2022	Member	Australian Society for Medical Research	Australia
  2021 - 2024	Member	Australasian Gene and Cell Therapy Society	Australia
  2018 - 2026	Member	Australia and New Zealand Society for Cell and Developmental Biology	Australia
  2017 - 2025	Member	Australian Society for Biochemistry and Molecular Biology	Australia

• Position: Grant Funded Researcher
• Email: yuchinnjoshua.chey@adelaide.edu.au
• Campus: West End Health Precinct
• Building: AHMS - Adelaide Health and Medical Sciences
• Org Unit: South Australian Immunogenomics Cancer Institute