Maurizio Costabile

Teaching Strengths

Biochemistry
Immunology
Interactive Simulations
Student engagement
Mind mapping

APrf Maurizio Costabile

Associate Professor of Biochemistry and Immunology Education

School of Pharmacy and Biomedical Sciences

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Available For Media Comment.

Hello and welcome to the homepage for Associate Professor Maurizio Costabile at the University of South Australia (UniSA). I have been employed at UniSA since 1998. I am a teaching-focussed, Associate professor in the Clinical and Health Sciences Academic Unit. I received my Bachelor of Science degree with First Class Honours in Biochemistry from the Flinders University of South Australia and I completed my PhD in Immunology at the Women's and Children's Hospital through the University of Adelaide. I was the Honours co-ordinator for the Laboratory Medicine Program for over 15 years and I was a higher degree research coordinator between 2016-24. I can be contacted for matters relating to Honours study, as well as postgraduate study within my academic unit. I am an active teacher, being responsible for Biochemistry (BIOL 2014) in SP2 and Immunology (BIOL 2037) in SP5. I have a strong interest in educational research, with an emphasis on Stroyline and Unity-based interactive simulations, mind mapping and 3D-printed objects as learning aids.

SoTL research

Associate Professor Maurizio Costabile is a teaching-focused academic who undertakes research in the Scholarship of Teaching and Learning (SoTL) at Adelaide University. His particular focus is on simulation-based pedagogy and the application of immersive technologies in laboratory education.

His research programme investigates how interactive digital simulations can be designed, implemented, and evaluated to improve student learning outcomes in undergraduate STEM and health sciences. This work has produced a substantial publication record in journals including Immunology & Cell Biology, Advances in Physiology Education, Biochemistry and Molecular Biology Education, and the International Journal of Science Education. His simulations have been adopted by institutions across Australia, New Zealand, the USA, and Europe, and evaluated through rigorous empirical study.

A second strand of his research examines cognitive presence and self-regulated learning in online allied health education, developed through a productive collaboration with PhD candidate Sandhya Maranna and published across multiple peer-reviewed journals. More recently, his work has extended into augmented reality for laboratory training, in collaboration with the STEM faculty and industry partners.

Maurizio supervises higher degree research students at the intersection of education technology, learning analytics, and immersive science education, and holds grants from bodies including the Australian Council of Deans of Science and the Australian Institute for Medical Scientists.

Year Citation
2026 Ebbert, D., Mirriahi, N., Wilson, N., Korolkiewicz, M., Fewster-Young, N., Lloyd, A., . . . Dawson, S. (2026). Mind wandering in Video-Based learning: Self-Regulated learning and student responses in a naturalistic setting. Metacognition and Learning, 21(1), 6-1-6-26.
DOI
2026 Mahdi, L., Denyer, G., & Costabile, M. (2026). Teaching third-year students MALDI-TOF using a combination of online interactive simulation and face-to-face practical inquiry. Journal of Microbiology and Biology Education, 27(1), 16 pages.
DOI
2025 Costabile, M., Bailey, S., & Denyer, G. (2025). A combined interactive online simulation and face-to-face laboratory enable undergraduate student proficiency in hemocytometer use, cell density and viability calculations. Immunology and Cell Biology, 103(2), 137-148.
DOI Scopus4 WoS4 Europe PMC4
2025 Costabile, M., & Denyer, G. (2025). Teaching the laboratory assessment of neutrophil chemotaxis: a simulation-based approach for undergraduate immunology. Immunohorizons, 9(11), vlaf049.
DOI
2025 Sakkal, S., & Costabile, M. (2025). Innovations in Immunology Education: bridging theory, practice and professional development. Immunology and Cell Biology, 103(2), 111-113.
DOI Scopus1 WoS1
2025 Vedova, C. D., Denyer, G., & Costabile, M. (2025). Combining face-to-face laboratory sessions and a computer simulation effectively teaches gene editing and DNA sequencing to undergraduate genetics students. Biochemistry and Molecular Biology Education, 53(3), 286-296.
DOI Scopus2 WoS1 Europe PMC2
2025 Clemson, M., Huang, A., Denyer, G., & Costabile, M. (2025). Teaching second-year biochemistry students the principles of an enzyme-catalyzed spectrophotometric assay with an online lab simulator. Biochemistry and Molecular Biology Education, 53(4), 370-380.
DOI Europe PMC1
2025 Pieschacon, J. M., Costabile, M., Cunningham, A., Zucco, J., Von Itzstein, G. S., & Smith, R. T. (2025). Smart Pipette: Elevating Laboratory Performance With Tactile Authenticity and Real-Time Feedback. IEEE Transactions on Visualization and Computer Graphics, 31(9), 5788-5800.
DOI Scopus2 Europe PMC1
2025 Costabile, M., Birbeck, D., & Aitchison, C. (2025). Using simulations to meld didactic and constructivist teaching methods in complex second year STEM courses. International Journal of Science Education, 47(2), 173-190.
DOI Scopus3 WoS3
2025 Maranna, S., Claassen, A., Joksimovic, S., Willison, J., Parange, N., & Costabile, M. (2025). Cognitive presence and self-regulated learning: Learning transfer in an online allied health course. Journal of University Teaching and Learning Practice, 22(1), 23 pages.
DOI Scopus1 WoS1
2025 Hastuti, S. D., Munro, J. L., Pyecroft, S. B., Barton, M. D., Costabile, M., & Jones, B. C. (2025). The Immune Responses and Histopathology of Asian Seabass (Lates calcarifer) Fed Diets Supplemented with Various Single Pure Nucleotides. Egyptian Journal of Aquatic Biology and Fisheries, 29(3), 2547-2585.
DOI
2025 Costabile, M., Caruso, C., Della Vedova, C., Bailey, S., & Mahdi, L. (2025). Leveraging computer-based simulations and immersive software technologies for enhanced student learning in laboratory medicine. ADVANCES IN PHYSIOLOGY EDUCATION, 49(2), 338-351.
DOI Scopus5 WoS5 Europe PMC3
2024 Harmon, J., Brown, A., Birbeck, D., Crockett, J., Panadgoo, S., Nawas, A., . . . Costabile, M. (2024). Interdisciplinary reflection by higher education academics using teaching squares: A scoping review. Nurse Education Today, 142(106353), 106353-1-106353-10.
DOI Scopus3 WoS2
2024 Maranna, S., Joksimovic, S., Willison, J., MacDougall, M., Parange, N., & Costabile, M. (2024). Student perspectives on learning transfer from online postgraduate sonography courses to traineeships: A pilot survey. Sonography, 12(1), 13-24.
DOI
2024 Costabile, M., Panadgoo, S., & Birbeck, D. (2024). Effective online material development: A micro-model taxonomy for designing simulations to maximise tertiary students’ learning. Journal of Applied Learning and Teaching, 7(2), 246-257.
DOI Scopus3
2024 Costabile, M., Simpson, B., Turkanovic, J., & Hughes, B. P. (2024). Enhancing teaching effectiveness in biochemistry labs: Author reflections and improvement strategies. Biochemistry and Molecular Biology Education, 52(5), 559-568.
DOI Scopus2
2024 Brown, A. E., Harmon, J., Birbeck, D., & Costabile, M. (2024). Interdisciplinary teaching squares enhance reflection and collegiality: A collaborative pedagogical approach. Nurse Education in Practice, 80(104121), 8 pages.
DOI Scopus2 WoS2
2024 Costabile, M., & Turkanovic, J. (2024). A guided interactive simulation as a tool to teach the classical approach of monoclonal antibody (MAb) production to undergraduate immunology students. Journal of Biological Education, 58(1), 130-143.
DOI Scopus7 WoS8
2023 Costabile, M. (2023). From the bench to the lectern: teaching immunology in higher education as a rewarding career opportunity. Immunology and Cell Biology, 101(3), 186-190.
DOI Scopus1 WoS1 Europe PMC1
2023 Kok, T. W., Izzo, A. A., & Costabile, M. (2023). Intracellular immunoglobulin A (icIgA) in protective immunity and vaccines. Scandinavian Journal of Immunology, 97(4, article no. e13253), 1-13.
DOI Scopus1 WoS2 Europe PMC1
2022 Donnellan, L., Simpson, B. S., Dhillon, V. S., Costabile, M., Fenech, M., & Deo, P. (2022). Folic acid deficiency increases sensitivity to DNA damage by glucose and methylglyoxal. Mutagenesis, 37(1), 24-33.
DOI Scopus10 WoS9 Europe PMC7
2022 Donnellan, L., Young, C., Simpson, B. S., Acland, M., Dhillon, V. S., Costabile, M., . . . Deo, P. (2022). Proteomic analysis of methylglyoxal modifications reveals susceptibility of glycolytic enzymes to dicarbonyl stress. International Journal of Molecular Sciences, 23(7, article no. 3689), 1-15.
DOI Scopus29 WoS28 Europe PMC28
2022 Donnellan, L., Young, C., Simpson, B. S., Dhillon, V. S., Costabile, M., Hoffmann, P., . . . Deo, P. (2022). Methylglyoxal impairs sister chromatid separation in lymphocytes. International Journal of Molecular Sciences, 23(8, article no. 4139), 1-11.
DOI Scopus4 WoS4 Europe PMC3
2022 Lewis, A. C., Pope, V. S., Tea, M. N., Li, M., Nwosu, G. O., Nguyen, T. M., . . . Pitson, S. M. (2022). Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.. Blood, 139(26), 3737-3751.
DOI Scopus46 WoS41 Europe PMC44
2022 Maranna, S., Willison, J., Joksimovic, S., Parange, N., & Costabile, M. (2022). Factors that influence cognitive presence: A scoping review. Australasian Journal of Educational Technology, 38(4), 95-111.
DOI Scopus21 WoS16
2022 Mahdi, L., Denyer, G., Caruso, C., & Costabile, M. (2022). Introducing First-Year Undergraduate Students the Fundamentals of Antibiotic Sensitivity Testing through a Combined Computer Simulation and Face-to-Face Laboratory Session. Journal of Microbiology and Biology Education, 23(2), 10 pages.
DOI Scopus10 WoS8 Europe PMC5
2022 Peake, B., Ghetia, M., Gerber, C., Costabile, M., & Deo, P. (2022). Role of saturated and unsaturated fatty acids on dicarbonyl–albumin derived advanced glycation end products in vitro. Amino Acids, 54(5), 721-732.
DOI Scopus7 WoS5 Europe PMC1
2021 Costabile, M. (2021). Design, implementation, and assessment of an interactive simulation to teach undergraduate immunology students hemolytic disease of the newborn. Advances in physiology education, 45(2), 299-306.
DOI Scopus11 WoS11 Europe PMC7
2021 Donnellan, L., Simpson, B., Dhillon, V. S., Costabile, M., Fenech, M., & Deo, P. (2021). Methylglyoxal induces chromosomal instability and mitotic dysfunction in lymphocytes. Mutagenesis, 36(5), 339-348.
DOI Scopus14 WoS15 Europe PMC14
2021 Hastuti, S. D., Munro, J., Pyecroft, S., Barton, M., Costabile, M., & Glencross, B. (2021). Supplementation of Nucleotides to Enhance Performance and Immune Responses of Asian Seabass. Jordan Journal of Biological Sciences, 14(4), 621-628.
DOI Scopus4
2020 Costabile, M., Nguyen, H., & Kenyon, A. (2020). Manipulating leukocyte populations to mimic immune disease states: a novel active approach to teaching flow cytometry to undergraduate immunology students. Advances in Physiology Education, 44(2), 247-253.
DOI Scopus5 WoS5 Europe PMC2
2020 Hastuti, S. D., Barton, M. D., Pyecroft, S. B., & Costabile, M. (2020). Assay optimization for measuring the alternate complement pathway activity in asian seabass (Lates calcarifer). Biodiversitas, 21(7), 3034-3040.
DOI Scopus7
2020 Costabile, M., Day, C., Garg, S., & Aldous, G. (2020). Development, implementation and evaluation of an innovative, project-based assignment for final year pharmacy students, relating to novel drug delivery systems. Pharmacy Education, 20(1), 67-75.
2020 Costabile, M. (2020). Using online simulations to teach Biochemistry laboratory content during COVID-19. Biochemistry and Molecular Biology Education, 48(5), 509-510.
DOI Scopus23 WoS22 Europe PMC13
2020 Costabile, M. (2020). Effectively teaching biochemistry practical's via simulations in the absence of face-to-face instruction. Australian Biochemist, 51(3), 31-32.
2020 O'Flaherty, J., & Costabile, M. (2020). Using a science simulation-based learning tool to develop students' active learning, self-confidence and critical thinking in academic writing. Nurse Education in Practice, 47(102839), 1-8.
DOI Scopus46 WoS34 Europe PMC10
2019 Costabile, M. (2019). Teaching hemolytic disease of the newborn (Erythroblastalis fetalis) to undergraduate immunology students through the use of an interactive simulation. Journal of Immunology, 202(S1), 1.
DOI
2019 Costabile, M., Nguyen, H., & Kenyon, A. (2019). Manipulating peripheral blood cell populations to mimic immune disease states: a novel approach to teach flow cytometry to undergraduate immunology students.. Journal of Immunology, 202(1), 1.
2019 Costabile, M., & Della Vedova, C. (2019). Development of an interactive simulation and app (PipetteMaster) to teach undergraduate students how to read, set and use an automatic laboratory pipette.. Journal of Immunology, 202(S1), 1.
DOI
2019 Costabile, M. (2019). Development and evaluation of an interactive simulation to teach undergraduate immunology students all stages of monoclonal antibody (mAb) production.. Journal of Immunology, 202(S1), 1.
2019 Neubauer, H. A., Tea, M. N., Zebol, J. R., Gliddon, B. L., Stefanidis, C., Moretti, P. A. B., . . . Pitson, S. M. (2019). Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene, 38(8), 1151-1165.
DOI Scopus27 WoS26 Europe PMC20
2019 Hastuti, S. D., Quach, A., Costabile, M., Barton, M. D., Pyecroft, S. B., & Ferrante, A. (2019). Measuring the Asian seabass (Lates calcarifer) neutrophil respiratory burst activity by the dihydrorhodamine-123 reduction flow cytometry assay in whole blood. Fish and Shellfish Immunology, 92, 871-880.
DOI Scopus6 WoS4 Europe PMC2
2019 Powell, J. A., Pitman, M. R., Zebol, J. R., Moretti, P. A., Neubauer, H. A., Davies, L. T., . . . Pitson, S. M. (2019). Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1. The Biochemical Journal, 476(21), 3211-3226.
DOI Scopus14 WoS14 Europe PMC12
2019 Garg, S., Aldous, G., Day, C., & Costabile, M. (2019). DEVELOPMENT, IMPLEMENTATION AND EVALUATION OF AN INNOVATIVE, PROJECT-BASED ASSIGNMENT FOR PHARMACY AND PHARMACEUTICAL SCIENCE STUDENTS, RELATING TO ADVANCED DRUG DELIVERY SYSTEMS. RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY, 15(5), E22.
DOI WoS1
2018 Kok, T., Costabile, M., Tannock, G., & Li, P. (2018). Colocalization of intracellular specific IgA (icIgA) with influenza virus in patients' nasopharyngeal aspirate cells. Journal of Virological Methods, 252, 8-14.
DOI Scopus6 WoS7 Europe PMC6
2017 Willem Jones, A., & Costabile, M. (2017). ComBio education symposium chairs summary. Australian Biochemist, 48(3), 36.
2017 Costabile, M., Bassal, N. K., Gerber, J. P., & Hughes, B. P. (2017). Inhibition of indoleamine 2,3-dioxygenase activity by fatty acids and prostaglandins: A structure function analysis. Prostaglandins leukotrienes and essential fatty acids, 122, 7-15.
DOI Scopus7 WoS5 Europe PMC6
2016 Bassal, N. K., Hughes, B. P., & Costabile, M. (2016). Prostaglandin D2 is a novel repressor of IFNγ induced indoleamine-2,3-dioxygenase via the DP1 receptor and cAMP pathway. Prostaglandins Leukotrienes and Essential Fatty Acids, 110, 48-54.
DOI Scopus10 WoS8 Europe PMC9
2016 Pitman, M. R., Costabile, M., & Pitson, S. M. (2016). Recent advances in the development of sphingosine kinase inhibitors. Cellular Signalling, 28(9), 1349-1363.
DOI Scopus85 WoS86 Europe PMC70
2014 Simpson, B., Luo, X., Costabile, M., Caughey, G., Wang, J., Claudie, D., . . . Semple, S. (2014). Polyandric acid A, a clerodane diterpenoid from the Australian medicinal plant Dodonaea polyandra, attenuates pro-inflammatory cytokine secretion in vitro and in vivo. Journal of Natural Products, 77(1), 85-91.
DOI Scopus23 WoS22 Europe PMC12
2012 Boog, B., Quach, A., Costabile, M., Smart, J., Quinn, P., Singh, H., . . . Ferrante, A. (2012). Identification and functional characterization of two novel mutations in the α-helical loop (residues 484-503) of CYBB/gp91phox resulting in the rare X91⁺ variant of chronic granulomatous disease. Human Mutation, 33(3), 471-475.
DOI Scopus7 WoS8 Europe PMC7
2012 Bassal, N. K., Hughes, B. P., & Costabile, M. (2012). Arachidonic acid and its COX1/2 metabolites inhibit interferon-γ mediated induction of indoleamine-2,3 dioxygenase in THP-1 cells and human monocytes. Prostaglandins, leukotrienes & essential fatty acids, 87(4-5), 119-126.
DOI Scopus14 WoS14 Europe PMC10
2010 Costabile, M. (2010). Determining the reactivity and titre of serum using a haemagglutination assay. Journal of visualized experiments, 35(article no. 1752), 1-2.
DOI Scopus4
2010 Costabile, M. (2010). Measuring the 50% haemolytic complement (CH50) activity of serum. Journal of visualized experiments, 37(article no. 1923), 1923.
DOI Scopus95 Europe PMC56
2009 Costabile, M. (2009). Monoclonal antibodies. Australian pharmacist, 28(5), 410-414.
2009 Costabile, M. (2009). Temozolomide. Australian pharmacist, 28(8), 671-673.
2008 Mukaro, V., Costabile, M., Murphy, K., Hii, C., Howe, P., & Ferrante, A. (2008). Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels. Arthritis Research & Therapy, 10(3), R57-R67.
DOI Scopus33 WoS31 Europe PMC24
2007 Moghaddami, N., Irvine, J., Gao, X., Grover, P., Costabile, M., Hii, C., & Ferrante, A. (2007). Novel action of n-3 polyunsaturated fatty acids - Inhibition of arachidonic acid-induced increase in tumor necrosis factor receptor expression on neutrophils and a role for proteases. Arthritis and Rheumatism, 56(3), 799-808.
DOI Scopus18 WoS16 Europe PMC11
2007 Chatziandreou, I., Gilmour, K. C., McNicol, A. M., Costabile, M., Sinclair, J., Cubitt, D., . . . Gaspar, H. B. (2007). Capture and generation of adenovirus specific T cells for adoptive immunotherapy. British Journal of Haematology, 136(1), 117-126.
DOI Scopus37 WoS31 Europe PMC30
2006 Costabile, M., Quach, A., & Ferrante, A. (2006). Molecular approaches in the diagnosis of primary immunodeficiency diseases. Human Mutation, 27(12), 1163-1173.
DOI Scopus20 WoS16 Europe PMC11
2005 Costabile, M., Hii, C., Melino, M., Easton, C., & Ferrante, A. (2005). The immunomodulatory effects of novel β-oxa, β-thia, and γ-thia polyunsaturated fatty acids on human T lymphocyte proliferation, cytokine production, and activation of protein kinase C and MAPKs. Journal of Immunology, 174(1), 233-243.
DOI Scopus27 WoS26 Europe PMC22
2004 Hii, C., Anson, D., Costabile, M., Mukaro, V., Dunning, K., & Ferrante, A. (2004). Characterization of the MEK5-ERK5 module in human neutrophils and its relationship to ERK1/ERK2 in the chemotactic response. Journal of Biological Chemistry, 279(48), 49825-49834.
DOI Scopus34 WoS33 Europe PMC33
2003 Moghaddami, N., Costabile, M., Grover, P., Jersmann, H., Huang, Z., Hii, C., & Ferrante, A. (2003). Unique effect of arachidonic acid on human neutrophil TNF receptor expression: Up-regulation involving protein kinase C, extracellular signal-regulated kinase, and phospholipase A₂¹. Journal of Immunology, 171(5), 2616-2624.
DOI Scopus17 WoS19 Europe PMC13
2003 Hii, C., Costabile, M., Mayne, G., Der, C., Murray, A., & Ferrante, A. (2003). Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells. Biochemical Journal, 370(2), 497-503.
DOI Scopus16 WoS13 Europe PMC13
2003 Moghaddami, N., Costabile, M., Grover, P., Jersmann, H., Huang, Z., Hii, C., & Ferrante, A. (2003). Unique effect of arachidonic acid on human neutrophil TNF receptor expression. Journal of immunology.
2001 Costabile, M., Hii, C., Robinson, B., Rathjen, D., Pitt, M., Easton, C., . . . Ferrante, A. (2001). A novel long chain polyunsaturated fatty acid, b-oxa 21:3n-3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals. Journal of Immunology, 167(7), 3980-3987.
DOI Scopus22 WoS23 Europe PMC15
1999 Li, Y., Hii, C., Costabile, M., Goh, D., Der, C., & Ferrante, A. (1999). Regulation of lymphotoxin production by the p21ras-raf-MEK-ERK cascade in PHA/PMA-stimulated Jurkat cells. Journal of Immunology, 162(6), 3316-3320.
DOI Scopus20 WoS20 Europe PMC15
1998 Hii, C., Huang, Z., Bilney, A., Costabile, M., Murray, A., Rathjen, D., . . . Ferrante, A. (1998). Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases. Journal of Biological Chemistry, 273(30), 19277-19282.
DOI Scopus99 WoS95 Europe PMC81

Year Citation
2025 Maranna, S., Joksimovic, S., Willison, J., Parange, N., & Costabile, M. (2025). The practical messiness of integrating learning transfer in an online allied health curriculum: a conceptual analysis. In M. A. Doolan, & L. Ritchie (Eds.), Source details - Title: Transforming Teaching Excellence: Future Proofing Education for All. UK: IFNTF Publishing.
2024 Aitchison, C., Bell, A., Bretana, N., Butler, M., Causby, R., Costabile, M., . . . Serrada, I. (2024). Case study 12: building a community of practice through gentle leadership. In K. Butler-Henderson, & A. Ashok (Eds.), Source details - Title: The Gentle Academic: Case studies in Higher Education Leadership (pp. 50-55). Australia: Charles Sturt University.
2023 Maranna, S., Willison, J., Joksimovic, S., Parange, N., & Costabile, M. (2023). Strategies for building sustainable and meaningful online learning communities in higher education. In M. Doolan, & L. Ritchie (Eds.), Event/exhibition information: IFNTF Symposathon, online, 19/09/2022-20/09/2022
Source details - Title: Reshaping Teaching Excellence: Pandemic and the New Now (pp. 45-60). UK: IFNTF Publishing.
2020 Costabile, M., & Timms, H. (2020). Developing an Online Simulation to Teach Enzyme Kinetics to Undergraduate Biochemistry Students. In Advances in Educational Marketing, Administration, and Leadership (pp. 281-302). IGI Global.
DOI
2020 Costabile, M., & Timms, H. (2020). Developing an online simulation to teach enzyme kinetics to undergraduate biochemistry students: an academic and educational designer perspective. In R. C. Plews, & M. L. Amos (Eds.), Source details - Title: Evidence-Based Faculty Development Through the Scholarship of Teaching and Learning (SoTL) (pp. 281-302). US: IGI Global.
DOI
2005 Ferrante, A., Hii, C. S., & Costabile, M. (2005). Regulation of Neutrophil Functions by Long Chain Fatty Acids. In D. I. Gabrilovich (Ed.), NEUTROPHILS: NEW OUTLOOK FOR OLD CELLS, 2ND EDITION (pp. 169-228). IMPERIAL COLL PRESS.
DOI WoS7

Year Citation
2025 Costabile, M., & Denyer, G. (2025). Simulating Innate immunity: Enhancing Undergraduate Learning through a Virtual Neutrophil Chemotaxis Assay. In JOURNAL OF IMMUNOLOGY Vol. 214 (pp. 1 page). OXFORD UNIV PRESS.
DOI
2025 Costabile, M., Bailey, S., & Denyer, G. (2025). A combined interactive online simulation and face-to-face laboratory enable undergraduate student proficiency in hemocytometer use, cell density and viability calculations. In JOURNAL OF IMMUNOLOGY Vol. 214 (pp. 157-158). OXFORD UNIV PRESS.
DOI
2019 Costabile, M. (2019). Teaching hemolytic disease of the newborn (Erythroblastalis fetalis) to undergraduate immunology students through the use of an interactive simulation. In JOURNAL OF IMMUNOLOGY Vol. 202 (pp. 1 page). CA, San Diego: AMER ASSOC IMMUNOLOGISTS.
2019 Costabile, M., & Della Vedova, C. (2019). Development of an interactive simulation and app (Pipette Master) to teach undergraduate students how to read, set and use and automatic laboratory pipette. In JOURNAL OF IMMUNOLOGY Vol. 202 (pp. 2 pages). CA, San Diego: AMER ASSOC IMMUNOLOGISTS.
2016 Costabile, M. (2016). Creation, implementation & assessment of an interactive digital simulation for the teaching of enzyme kinetics at a university level. In International Science Education Conference. Italy.
2012 Kamal Bassal, N. M., Hughes, B. P., & Costabile, M. (2012). Tryptophan Metabolism-Indoleamine 2,3-Dioxygenase-Friend and Foe. In Journal of Metabonomics & Metabolites Vol. 1 (pp. 1-3). US: SciTechnol-International Publisher of Science, Tec....
DOI

Year Citation
2023 Mahdi, L., Denyer, G., & Costabile, M. (2023). Embracing innovation in microbiology education: Integrating online interactive simulation and F-2-F practical inquiry when teaching MADLI-TOF. Poster session presented at the meeting of ACSME 2023 Proceedings: The Changing Climate of Science Education. Australia: University of Sydney.
2023 Costabile, M., Bailey, S., & Denyer, G. (2023). From virtual to practical: Integrating an online simulation and face-to-face learning to enable hemocytometer proficiency. Poster session presented at the meeting of ACSME 2023 Proceedings: The Changing Climate of Science Education. Australia: University of Sydney.
2019 Hastuti, S., Barton, M., Pyecroft, S., & Costabile, M. (2019). Optimisation of conditions for measuring the alternate complement pathway activity in Asian seabass (Lates calcarifer).. Poster session presented at the meeting of International Conference of Aquaculture. Indonesia.
2019 Costabile, M. (2019). Development and evaluation of an interactive simulation to teach undergraduate immunology students all stages of monoclonal antibody (mAb) production. Poster session presented at the meeting of 48th Annual Scientific Meeting of The Australian and New Zealand Society for Immunology: Poster session. Australia: ICMS Australasia.
2018 Costabile, M., Kuit, T., & LeBard, R. (2018). How to win a teaching and learning award. Poster session presented at the meeting of ComBio 2018 Symposium. Australia.
2018 Ruggero, A., Nguyen, H., & Costabile, M. (2018). Teaching immunology students about primary immunodeficiency disease diagnosis through a modified flow cytometry practical. Poster session presented at the meeting of TechNet 2018 Posters. Australia: University of Queensland.
2017 Kok, T., & Costabile, M. (2017). Interaction of intracellular specific IgA (icIgA) with uncleaved influenza virus haemagglutinin (HA0) in patient respiratory exudate cells can inform vaccine design. Poster session presented at the meeting of International Union of Microbiological Societies Congress (IUMS). Singapore: International Union of Microbiological Societies.
2017 Costabile, M. (2017). The development of innovative and engaging digital simulations for the laboratory-based teaching of biochemistry. Poster session presented at the meeting of 26th FAOBMB Conference. Japan: FAOBMB.
2016 Costabile, M. (2016). Assessment of an interactive simulation for the teaching of enzyme kinetics.. Poster session presented at the meeting of ComBio 2016 Symposium Abstracts. Australia.
2016 Costabile, M. (2016). Improving student learning of biochemistry using simulations. Poster session presented at the meeting of OLC Innovate 2016 - Program Listing. US: Online Learning Consortium, Inc..
2014 Costabile, M. (2014). Assessment of an e-Learning simulation for the teaching of enzyme kinetics. Poster session presented at the meeting of HERGA Conference - Changing Horizons: Local Learning for Global Impact. Adelaide, Australia: Education Research Group of Adelaide.
2013 Quach, A., Lester, S., Smith, A., Hissaria, P., Al Kindi, M., Heddle, R., . . . Costabile, M. (2013). A HAPLOTYPE/DIPLOTYPE ASSOCIATED WITH DELAYED TACI UPREGULATION AND INCREASED RISK OF COMMON VARIABLE IMMUNODEFICIENCY. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY-BLACKWELL.

Year Citation
- Ebbert, D., Mirriahi, N., Wilson, N., Korolkiewicz, M., Fewster-Young, N., Lloyd, A., . . . Dawson, S. (n.d.). Mind Wandering in Video-Based Learning: Self-Regulated Learning and Student Responses in a Naturalistic Setting.
DOI
  • Enhancing Laboratory Medicine Education: A Digital Approach to teaching Quality Control in Clinical Diagnostics, Australian Institute of Medical and Clinical Scientists - Education and Leadership/Management Grant, ($10,000), 01/10/2025 - 01/10/2026

  • Identification and Resolution of Transition Shock for Laboratory Medicine Students undertaking Work Integrated Learning (WIL) Laboratory Placement. Australian Council of Deans of Science (ACDS) ($5,277), 2023.

  • Development of a “Complement” teaching simulation. Pharmacy and Medical Science Teaching fund, ($1000). 2019.

  • Teaching Leadership Funding. University of South Australia, ($2000), 2016.
  • Development of interactive simulations to enhance student teaching and learning of undergraduate Biochemistry and Immunology. UniSA Digital Teaching Equipment Fund ($5,700), 2015.
  • Funding to Purchase a Becton Dickinson, Accuri Flow Cytometer. Contributor to the application, flow cytometer is used for both teaching and research purposes. ($80,000), 2013
  • NHMRC Development Grant. ($276,598.06), 2011-13.
  • Mind mapping: Enhancing student engagement and linkage of scientific knowledge. UniSA Teaching Development Grant, ($9,000), 2007.
  • Tracking changes in B-lymphocyte gene expression in patients suffering from common variable immunodeficiency. Australian Competitive Grant Scheme, ($20,000), 2005.
  • Equipment grant (Thermal cycler). Rebecca L Cooper Medical Foundation, $11,000, 2004.
  • M.S. McLeod travel scholarship. Dept of Immunology, Great Ormond Street Hospital for Sick Children, London ($25,000), 2003-4
  • Inhibition of Natural killer cell activity by engineered polyunsaturated fatty acids. UniSA Research Grant, ($3500), 2001.
  • Intracellular signalling in neonatal T cells. UniSA Research Grant, ($4000), 2000.
  • Australian Postgraduate Award (Industry) Scholarship ($20,000/yr), 1995.

Courses I teach

  • BIOL 2027 Biochemistry (AU, 2026)
  • BIOL 2034 Immunology (AU, 2026)
  • BIOL 2014 Biochemistry (UniSA, 2025)
  • BIOL 2037 Immunology (UniSA, 2025)

Programs I'm associated with

  • IBBL - Bachelor of Laboratory Medicine
  • IBMS - Bachelor of Medical Science
  • IBNF - Bachelor of Nutrition and Food Sciences
  • IBPS - Bachelor of Pharmaceutical Sciences

Date Role Research Topic Program Degree Type Student Load Student Name
2022 Co-Supervisor Hand skill training with custom haptics, real-time visual instruction, and immersive technologies Doctor of Philosophy Doctorate Full Time Mr Juan Pieschacon Aponte
2017 External Supervisor The use of nucleotides as an immune nutrition in innate and adaptive immunity in Barramundi Doctor of Philosophy Doctorate Full Time Mrs Sri Dwi Hastuti

Date Role Research Topic Program Degree Type Student Load Student Name
2019 - 2025 Principal Supervisor Exploring the relation between cognitive presence, self-regulated learning and learning transfer in online postgraduate medical sonography students Doctor of Philosophy Doctorate Part Time Mrs Sandhya Maranna
2019 - 2024 Co-Supervisor Targeting sphingosine kinase 1 to overcome venetoclax resistance in acute myeloid leukemia Doctor of Philosophy Doctorate Full Time Mr Gus Nwosu
2019 - 2023 Co-Supervisor Methylglyoxal induces chromosomal instability under normal and folic acid deficient conditions Doctor of Philosophy Doctorate Part Time Mr Leigh Donnellan
2017 - 2023 Principal Supervisor The role of fatty acids on dicarbonyl- induced protein glycation, receptor expression and inflammatory biomarkers Master of Research (Pharmaceutical Science) Master Part Time Mr Brock Peake
2009 - 2014 Principal Supervisor Regulation of indoleamine 2,3-dioxygenase (IDO) by fatty acids and their eicosanoid derivatives in THP-1 cells and human monocytes Doctor of Philosophy Doctorate Full Time Mrs Nesrine Kamal Bassal
2006 - 2012 Principal Supervisor The characterisation of a novel haplotype within TNFRSF13B associated with increased risk of development of common variable immunodeficiency Doctor of Philosophy Doctorate Full Time Mr Alexander Quach

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2022 - 2025 Principal Supervisor Exploring the relationship between cognitive presence, self-regulated learning and learning transfer in online post graduate medical sonography students University of South Australia - Doctorate Part Time Sandhya (Sandy) Maranna

Date Topic Location Name
2025 - ongoing SoTL mentoring University of New South Wales Nirmani Wijenayake Gamachchige
2022 - 2022 ASI Immunology mentor program University of Melbourne A/Prof Odilia Wijburg

Date Role Editorial Board Name Institution Country
2025 - ongoing Board Member Biochemistry and Molecular Biology Education NA United States
2025 - ongoing Board Member Biochemistry and Molecular Biology Education NA United States
2024 - ongoing Associate Editor Immunology and Cell Biology NA Australia

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