Dr Leigh Donnellan

Research Associate

School of Pharmacy and Biomedical Sciences

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.


Year Citation
2025 Lau, D., Donnellan, L., Briggs, M., Klingler Hoffmann, M., & Hoffmann, P. (2025). MALDI Mass spectrometry imaging of metabolites in cereal grains and legumes: repurposing for industrial applications. Food Reviews International, 41(4), 1200-1221.
DOI Scopus4 WoS4
2025 Lau, D., Donnellan, L., Harris, J. C., Hayes, J. E., Croser, J., & Hoffmann, P. (2025). Proteomic and lipidomic analyses reveal novel molecular insights into oat (Avena sativa L.) lipid regulation and crosstalk with starch synthesis during grain development.. International Journal of Biological Macromolecules, 306(Part 1), 141305-1-141305-11.
DOI
2025 Lau, W. C. D., Donnellan, L., Harris, J. C., Seidel, J., Hayes, J. E., Croser, J., & Hoffmann, P. (2025). Coupling proteomics and lipidomics for insights into regulation of oat (Avena sativa) grain lipid synthesis. Food Chemistry, 478(143644), 143644-1-143644-12.
DOI Scopus4 WoS2
2025 Aralappanavar, V. K., Sarkar, B., Doolette, C. L., Rose, M., Donnellan, L., Smith, E., . . . Lombi, E. (2025). A diffusive gradients in thin-films (DGT) methodology for in situ measurement of imazamox and imazapyr herbicide residues. Talanta, 295(128350), 1-11.
DOI Scopus2 WoS2
2025 Aralappanavar, V. K., Sarkar, B., Doolette, C. L., Donnellan, L., Mason, S., Rose, M., . . . Lombi, E. (2025). Diffusive gradients in thin films (DGT) for measuring potentially bioavailable pesticide residues in soil systems: current challenges and perspectives. Critical Reviews In Environmental Science And Technology, online(17), 1-22.
DOI
2025 Subramaniam, S., Donnellan, L., Wignall, A., Woodcock, J., Coolen, C., Pitson, S., . . . Joyce, P. (2025). Polymeric-lipid nanoparticles that leverage cationic helper lipids and the protein corona for lung-targeted delivery of a novel anti-cancer drug. Journal of Controlled Release, 388(Pt 1), 15 pages.
DOI
2025 Desire, C. T., Dilmetz, B. A., Degenhardt, J., Donnellan, L., Condina, M. R., Young, C., & Hoffmann, P. (2025). The Importance of Denaturing Conditions for Protein and Peptide Quantification by Tryptophan Fluorescence. ACS Omega, 10(46), 56795-56805.
DOI
2025 Donnellan, L., Fenech, M., Dhillon, V. S., Young, C., Hoffmann, P., & Deo, P. (2025). Role of methylglyoxal protein modifications in DNA damage and chromosomal instability: Emerging molecular mechanisms. Mutation Research Reviews in Mutation Research, 796(108558), 10 pages.
DOI Scopus4 WoS4 Europe PMC4
2025 Lee, J. H., Sumer Bayraktar, Z., Mittal, P., Donnellan, L., Young, C., Rushworth, R. L., . . . Meyer, E. J. (2025). Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients. Clinica Chimica Acta, 567(120108), 1-8.
DOI Scopus1 WoS1 Europe PMC1
2024 Seidel, J. D., Condina, M. R., Klingler Hoffmann, M., Young, C., Donnellan, L., Kyngdon, C., & Hoffmann, P. (2024). Development of an optimized LC-MS workflow for host cell protein characterization to support upstream process development. Journal of Proteome Research, 24(1), 234-243.
DOI Scopus1 WoS1
2024 Lau, W. C. D., Donnellan, L., Briggs, M., Rupasinghe, T., Harris, J. C., Hayes, J. E., & Hoffmann, P. (2024). Sodium doping and trapped ion mobility spectrometry improve lipid detection for novel MALDI-MSI analysis of oats. Food Chemistry, 433(137275), 1-10.
DOI Scopus10 WoS10 Europe PMC8
2023 Dilmetz, B. A., Desire, C. T., Donnellan, L., Meneses, J., Klingler Hoffmann, M., & Young, C. (2023). Assessment of yeast physiology during industrial-scale brewing practices using the redox-sensitive dye resazurin. Yeast, 40(5-6), 171-181.
DOI Scopus2 WoS2 Europe PMC1
2023 Subramaniam, S., Joyce, P., Donnellan, L., Young, C., Wignall, A., Hoffmann, P., & Prestidge, C. A. (2023). Protein adsorption determines pulmonary cell uptake of lipid-based nanoparticles. Journal of Colloid and Interface Science, 641, 36-47.
DOI Scopus32 WoS31 Europe PMC23
2022 Donnellan, L., Simpson, B. S., Dhillon, V. S., Costabile, M., Fenech, M., & Deo, P. (2022). Folic acid deficiency increases sensitivity to DNA damage by glucose and methylglyoxal. Mutagenesis, 37(1), 24-33.
DOI Scopus9 WoS9 Europe PMC6
2022 Donnellan, L., Young, C., Simpson, B. S., Acland, M., Dhillon, V. S., Costabile, M., . . . Deo, P. (2022). Proteomic analysis of methylglyoxal modifications reveals susceptibility of glycolytic enzymes to dicarbonyl stress. International Journal of Molecular Sciences, 23(7, article no. 3689), 1-15.
DOI Scopus26 WoS25 Europe PMC25
2022 Donnellan, L., Young, C., Simpson, B. S., Dhillon, V. S., Costabile, M., Hoffmann, P., . . . Deo, P. (2022). Methylglyoxal impairs sister chromatid separation in lymphocytes. International Journal of Molecular Sciences, 23(8, article no. 4139), 1-11.
DOI Scopus4 WoS4 Europe PMC3
2021 Forbes, J. M., Le Bagge, S., Righi, S., Fotheringham, A. K., Gallo, L. A., McCarthy, D. A., . . . O’Moore-Sullivan, T. (2021). Advanced glycation end products as predictors of renal function in youth with type 1 diabetes. Scientific Reports, 11(1), 9422-1-9422-10.
DOI Scopus9 WoS9 Europe PMC8
2021 Donnellan, L., Simpson, B., Dhillon, V. S., Costabile, M., Fenech, M., & Deo, P. (2021). Methylglyoxal induces chromosomal instability and mitotic dysfunction in lymphocytes. Mutagenesis, 36(5), 339-348.
DOI Scopus14 WoS14 Europe PMC14
2021 Snelson, M., Min Tan, S., Clarke, R. E., de Pasquale, C., Donnellan, L., Deo, P., & Coughlan, M. T. (2021). Processed foods drive intestinal barrier permeability and microvascular diseases. Science Advances, 7(14, article no. eabe4841), 1-15.
DOI Scopus126 WoS123 Europe PMC96
2020 Deo, P., McCullough, C. L., Almond, T., Jaunay, E. L., Donnellan, L., Dhillon, V. S., & Fenech, M. (2020). Dietary sugars and related endogenous advanced glycation end-products increase chromosomal DNA damage in WIL2-NS cells, measured using cytokinesis-block micronucleus cytome assay. Mutagenesis, 35(2), 1-9.
DOI Scopus17 WoS19 Europe PMC11
2020 Deo, P., Dhillon, V. S., Lim, W. M., Jaunay, E. L., Donnellan, L., Peake, B., . . . Fenech, M. (2020). Advanced glycation end-products accelerate telomere attrition and increase pro-inflammatory mediators in human WIL2-NS cells. Mutagenesis, 35(3), 291-297.
DOI Scopus18 WoS18 Europe PMC12
  • Exploring Fucoidan’s Role as a Gut-Protective Prebiotic, Marine Bioproducts CRC, 19/01/2026 - 19/01/2028

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor Food safety and key nutritional analysis of black soldier fly (Hermetia illucens L) larvae: an alternative protein source Doctor of Philosophy Doctorate Part Time Samuel Andrew Mallard
2023 Co-Supervisor Mass spectrometry and spectroscopic analytical approaches for directed monoclonal antibody formulation development Doctor of Philosophy Doctorate Full Time Abdulafeez Akinloye
2023 Co-Supervisor 111153 - Mass Spectrometry assays for protein biomarker for the early detection of ovarian cancer - Master Full Time Mr Nicholas Chappell

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