
Professor Mark Hutchinson
Director - Centre for Nanoscale BioPhotonics
School of Biomedicine
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Mark Hutchinson is an ARC Future fellow and Professor within the Adelaide Medical School, the Director of the ARC Centre of Excellence for Nanoscale BioPhotonics. Mark is also President of Science and Technology Australia, the peak body in Australia that represents 110,000 scientists.
The team he leads is world-leading, developing innovative technologies that allow for the early diagnosis and treatment of neurological diseases, including pain. Professor Hutchinson’s research explores the “other brain” or the other 90% of cells in the brain and spinal cord. These immune-like cells are termed glia. Mark’s research has implicated the brain immune-like cells in the action of drugs of dependence and the negative side effects of pain treatments. He has pioneered research which has led to the discovery of novel drug activity at innate immune receptors. His work has enabled the translation of compounds at the lab bench to clinical agents used at the bedside.
In his role as Director of the CNBP he is responsible for the research program of the ARC Centre of Excellence with $50M of funding headquartered at The University of Adelaide, with nodes at Macquarie University and UNSW, Sydney, the RMIT, Melbourne and Griffith University Qld. The CNBP is partnered with universities and companies in Europe, the US and China, as well as other Australian institutions. Prof Hutchinson’s work with the CNBP is to "Discover new approaches to measure nano-scale dynamic phenomena in living systems” and allow the first minimally invasive realtime visualisations of the “other brain”.
Mark serves as a founding member of the Operating in Contaminated Environments Advisory Council for the DSTG CBRN STaRShot, is a founding member of the executive of the Animal Welfare Collaborative (TAWC), is the Chair of the Australian Pain Solutions Research Alliance, the co-chair of the Safeguarding Australia through Biotechnology Response and Engagement (SABRE) Alliance, a Ministerial appointment to the Australian Research Council CEO Advisory Council, and one of three eminent academics reviewing the ARC Federal Legislation.
- My Research
- Career
- Publications
- Grants and Funding
- Teaching
- Supervision
- Professional Activities
- Contact
Mark’s research has implicated the brain immune-like cells in the action of drugs of dependence and the negative side effects of pain treatments.
Mark has published over 240 papers in journals and refereed conference proceedings.
The CNBP is an ARC Centre of Excellence with $50M of funding committed for 7 years, headquartered at The University of Adelaide, with nodes at Macquarie University, Sydney; the RMIT, Melbourne; and Griffith University, the Gold Coast. We are partnered with universities and companies in Europe, the US and China, as well as other Australian institutions.
The CNBP has a mission to "Discover new approaches to measure nano-scale dynamic phenomena in living systems".
I have several openings for research projects within my team for PhD students
Project 1
Title: Cell-based biomarker of persistent pain in livestock
Description: This project will translate a human biomarker of pain into the livestock setting to predict the chronic pain of animal husbandry practices.
Project available for: HDR and/or Honours
Location: Roseworthy and North Tce
Research Project start date: Semester 1 2023
Special requirements: surgical skills, cell culture experience and some bioinformatics
Project 2
Title: Transcriptome biomarker of persistent pain in livestock
Description: This project will translate a human biomarker of pain into the livestock setting to predict the chronic pain of animal husbandry practices.
Project available for: HDR and/or Honours
Location: Roseworthy and North Tce
Research Project start date: Semester 1 2023
Special requirements: surgical skills, bioinformatics and molecular techniques.
Project 3
Title: Modeling persistent pain in livestock
Description: This project will translate a human model of neuroimmune pain into the livestock setting to better predict the consequences of chronic pain in livestock and allow the development of novel pain therapies.
Project available for: HDR and/or Honours
Location: Roseworthy and North Tce
Research Project start date: Semester 1 2023
Special requirements: surgical skills, animal handling experience and molecular techniques.
Project 4
Title: Drug discovery for novel treatments of persistent pain in livestock
Description: This project will translate neuroimmune pain targeted treatments into the livestock setting to better treat chronic pain in livestock and allow the development of deployable pain therapies.
Project available for: HDR and/or Honours
Location: Roseworthy and North Tce
Research Project start date: Semester 1 2023
Special requirements: surgical skills, animal handling experience and molecular pharmacology techniques.
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Appointments
Date Position Institution name 2014 - ongoing Director Australian Research Council Centre of Excellence for Nanoscale BioPhotonics 2014 - ongoing Professor University of Adelaide 2013 - 2014 Associate Professor University of Adelaide 2011 - 2012 ARC Research Fellow University of Adelaide 2009 - 2010 NHMRC CJ Martin Research Fellow University of Adelaide 2005 - 2008 Postdoc Research Fellow University of Colorado Boulder -
Awards and Achievements
Date Type Title Institution Name Country Amount 2015 Award The James McWha Award of Excellence University of Adelaide Australia - 2014 Award Brain Behavior & Immunity Reviewer of the Year Elsevier Australia - 2013 Nomination South Australian Leading Light Finalist Australian Society for Medical Research (ASMR) Australia - 2013 Award Robert Ader New Investigator Psychoneuroimmunology Research Society - - 2012 Nomination Young Researcher Award Finalist Scopus - - 2012 Award Tess Cramond Lecturer Australian Pain Society Australia - 2011 Award College on Problems of Drug Abuse Early Career Prize - - - 2010 Award South Australian Tall Poppy Science Awardee - Australia - 2009 Award Denis Wade Johnson & Johnson New Investigators The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) - - 2007 Award National Institute for Drug Addiction Young Investigator National Institute for Drug Addiction Australia - 2006 Award Society on Neuroimmune Pharmacology Travel Society on Neuroimmune Pharmacology - - 2005 Award Oral Presentation Finalist Winner Front Range Neuroscience Group - - 2005 Fellowship American Australian Association Merck Company Foundation Fellow American Australian Association Merck Company Foundation - - 2005 Nomination Chapter travel award Front Range Neuroscience Group - - 2005 Award Chapter oral presentation winner Front Range Neuroscience Group - - 2005 Award Recipient of a British Council Travel British Council - - 2004 Award Australian FreshScience Winner Fresh Science Australia - -
Education
Date Institution name Country Title 2004 University of Adelaide Australia PhD in Medicine 1999 University of Adelaide Australia BSc (First class Honours) in Pharmacology 1998 University of Adelaide Australia BSc -
Research Interests
Basic Pharmacology Clinical Pharmacology and Therapeutics Immunology Innate Immunity Nanomaterials Nanophotonics Nanoscience & Nanotechnology Nanotechnology Neurosciences Pharmacogenomics Pharmacology and Pharmaceutical Sciences Photodetectors, Optical Sensors and Solar Cells Neuroscience, Behaviour and Brain Health Surgical and Health Systems Innovation Pregnancy and Birth Early Origins of Health Immunology and Infection Translational Health Outcomes Innovative Therapeutics
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Journals
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Book Chapters
Year Citation 2022 Mustafa, S., Evans, S., Barry, B., Barratt, D., Wang, Y., Lin, C., . . . Hutchinson, M. R. (2022). Toll-Like Receptor 4 in Pain: Bridging Molecules-to-Cells-to-Systems.. In V. Kumar (Ed.), Toll-like Receptors in Health and Disease. Handbook of Experimental Pharmacology (Vol. 276, pp. 239-273). Springer Berlin Heidelberg.
Europe PMC12018 Holmes, J., Corrigan, F., & Hutchinson, M. R. (2018). Neuroimmunopharmacology at the Interface of Inflammation and Pharmacology Relevant to Depression. In B. T. Baune (Ed.), Inflammation and Immunity in Depression Basic Science and Clinical Applications (pp. 223-240). United Kingdom: Academic Press.
2015 Thomas, J., Sanam, M., Johnson, J., & Nicotra, L. (2015). The relationship between opioids and immune signalling in the spinal cord. In Pain Control (Vol. 227, pp. 207-238). Springer Berlin Heidelberg.
Scopus16 Europe PMC82014 Wang, X., Cochran, T. A., Hutchinson, M. R., Yin, H., & Watkins, L. R. (2014). Drug addiction. In M. E. Tremblay, & A. Sierra (Eds.), Microglia in health and disease (pp. 299-317). Online: Springer New York.
Scopus52013 Sumracki, N., Nicotra, L., Kwok, Y., Liu, L., Steeg, K., Watkins, L., & Hutchinson, M. (2013). The future: new concepts and potential therapies. In C. Toth, & D. Moulin (Eds.), Neuropathic pain: causes, management and understanding (1 ed., pp. 341-356). United Kingdom: Cambridge University Press.
2013 Wu, Y., & Hutchinson, M. (2013). Therapeutic strategies to treat alcohol-related disorders targeting central immune signaling. In C. Cui, L. Grandison, & A. Noronha (Eds.), Neural-Immune Interactions in Brain Function and Alcohol Related Disorders (1 ed., pp. 535-559). United States: Springer.
2013 The Wiley‐Blackwell Handbook of Psychoneuroimmunology (2013). Wiley.
2013 The Wiley‐Blackwell Handbook of Psychoneuroimmunology (2013). Wiley.
2013 Grace, P. M., Watkins, L. R., & Hutchinson, M. R. (2013). Immune-to-Brain Communication in Pain: Historical Perspectives, New Directions. In The Wiley-Blackwell Handbook of Psychoneuroimmunology (pp. 176-197). Wiley.
2012 Grace, P., Watkins, L., & Hutchinson, M. (2012). The Role of the Immune System in Chronic Pain Comorbidities. In M. Giamberardino, & T. Jensen (Eds.), Pain Comorbidities: Understanding and Treating the Complex Patient (1 ed., pp. 137-155). Seattle, WA: USA: IASP Press (International Association for the Study of Pain). 2009 Gordon, A., Hutchinson, M., La Vincente, S., Mitchell, T., Morrish, G., Newcombe, D., . . . White, J. (2009). Pharmacology of opioid agonists and antagonists. In R. Mattick, R. Ali, & N. Lintzeris (Eds.), Pharmacotherapies for the Treatment of Opioid Dependence: Efficacy, Cost-Effectiveness and Implementation Guidelines (pp. 15-53). New York, USA: Informa. 2007 Watkins, L. R., Wieseler-Frank, J., Hutchinson, M. R., Ledeboer, A., Spataro, L., Milligan, E. D., . . . Maier, S. F. (2007). Neuroimmune interactions and pain: The role of immune and glial cells. In Psychoneuroimmunology, Two-Volume Set (Vol. 1, pp. 393-414). Elsevier.
Scopus62006 Watkins, L. R., Wieseler-Frank, J., Hutchinson, M. R., Ledeboer, A., Spataro, L., Milligan, E. D., . . . Maier, S. F. (2006). Neuroimmune Interactions and Pain: The Role of Immune and Glial Cells. In Psychoneuroimmunology (pp. 393-414).
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Conference Papers
Year Citation 2019 Schartner, E., Musolino, S., Salem, A., Hutchinson, M., & Monro, T. (2019). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015 (pp. 1). online: OSA Publishing. 2019 Schartner, E., Tsiminis, G., Henderson, M., Hutchinson, M., & Monro, T. (2019). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015. online: OSA Publishing. 2019 Kostecki, R., Zhang, B., El Habti, A., Arman, A., Hutchinson, M., Tricker, P., . . . Ebendorff-Heidepriem, H. (2019). Reversible protein carbonylation in-vivo biosensor. In osapublishing.org Vol. Part F166-Sensors 2019 (pp. 1-2). online: OSA.
2019 Peng, L., Khalid, A., Warren-Smith, S. C., Arman, A., Schartner, E. P., Sylvia, G. M., . . . Li, J. (2019). Chemical sensing based on silk coated exposed-core fibers. In E. M. Goldys, & B. C. Gibson (Eds.), Biophotonics Australasia 2019 Vol. 11202 (pp. 112020G-1-112020G-2). Bellingham, Washington: SPIE.
2019 Kostecki, R., Zhang, B., El Habti, A., Arman, A., Hutchinson, M. R., Tricker, P. J., . . . Ebendorff-Heidepriem, H. (2019). Optical fiber based in-vivo oxidative stress biosensor. In Proceedings of SPIE - The International Society for Optical Engineering Vol. 11202 (pp. 1-3). online: SPIE.
WoS12017 Hutchinson, M. R. (2017). The importance of knowing you are sick: Biophotonics for the 'Other' brain. In Optics InfoBase Conference Papers Vol. Part F41-CLEO_SI 2017 (pp. 1 page). San Jose, CA: IEEE.
WoS12017 Liu, G., Zhang, K., Nadort, A., Hutchinson, M., & Goldys, E. (2017). An optical fibre based ex-vivo device for detection of cytokines. In IET Conference Publications Vol. 2017 (pp. 1-4). online: IET Digital Library.
2017 Tsiminis, G., Schartner, E., Brooks, J., & Hutchinson, M. (2017). Measurements of vitamin B12 in human blood serum using resonance Raman spectroscopy. In Proceedings of the 29th IEEE Photonics Conference (pp. 684-685). Waikoloa, HI: IEEE.
Scopus1 WoS12016 Tsiminis, G., Schartner, E., Bekteshi, M., Hutchinson, M., & Ebendorff-Heidepriem, H. (2016). Hollow-core optical fibers made by glass billet extrusion as sensors for raman spectroscopy. In Optics InfoBase Conference Papers Vol. Part F3-ACOFT 2016 (pp. 1-2). online: OSA.
2016 Musolino, S., Schartner, E., Tsiminis, G., Salem, A., Monro, T., & Hutchinson, M. (2016). A portable optical fiber probe for in vivo brain temperature measurements. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 4 pages). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING.
Scopus2 WoS12016 Staikopoulos, V., Gosnell, M., Anwer, A., Mustafa, S., Hutchinson, M., & Goldys, E. (2016). Hyperspectral imaging of endogenous fluorescent metabolic molecules to identify pain states in central nervous system tissue. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 1-8). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING.
Scopus3 WoS32016 Peddie, V., Heng, S., Mustafa, S., Thomas, J., Hutchinson, M., & Abell, A. (2016). Shapeshifting photoswitchable azobenzene compounds and their biological applications. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 4 pages). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING.
2016 Tsiminis, G., Schartner, E., Brooks, J., & Hutchinson, M. (2016). Measurements of vitamin B12 in human blood serum using resonance Raman spectroscopy. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE: SPIE BioPhotonics Australasia Conference Vol. 10013 (pp. 100130M-1-100130M-4). Adelaide, Australia: SPIE.
2016 Tsiminis, G., Schartner, E., Hutchinson, M., & Ebendorff-Heidepriem, H. (2016). Hollow core optical fibres made by glass billet extrusion as sensors for Raman spectroscopy. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 4 pages). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING.
2016 Bajic, J., Whittaker, A., Bobrovskaya, L., Hutchinson, M., & Howarth, G. (2016). Intestinal mucositis induced by 5-Fluorouracil results in glial changes modified by analgesics via neuro-immune mechanisms. In Australian Society for Medical Research. Adelaide. 2016 Whittaker, A. L., Bajic, J. E., Bobrovskaya, L., Hutchinson, M. R., & Howarth, G. S. (2016). Chemotherapy Induces Intestinal Inflammation and Central Changes Which Are Modified by Analgesics via Neuro-Immune Mechanisms. In GASTROENTEROLOGY Vol. 150 (pp. S52). San Diego, CA: W B SAUNDERS CO-ELSEVIER INC.
2015 Dodds, K., Beckett, E., Staikopoulos, V., Evans, S., & Hutchinson, M. (2015). Novel mouse model of endometriosis permits identification of spinal glia and nociception characteristics involved in pelvic pain. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 267). Cairns, AUSTRALIA: WILEY-BLACKWELL. 2015 Staikopoulos, V., Jin, D., Lu, Y., Gibson, B., Reineck, P., Goldys, E., . . . Hutchinson, M. (2015). Ultra-structural imaging in cleared mouse cns using nanoparticles. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 382). Cairns, AUSTRALIA: WILEY-BLACKWELL. 2015 Jacobsen, J., Staikopoulos, V., & Hutchinson, M. (2015). Optimisation and utilisation of a novel whole-brain imaging technique (clarity) to analyse addiction-like behaviours. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 351). Cairns, AUSTRALIA: WILEY-BLACKWELL. 2015 Schartner, E., Musolino, S., Salem, A., Hutchinson, M., & Monro, T. (2015). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Optics InfoBase Conference Papers. 2015 Schartner, E. P., Musolino, S., Salem, A., Hutchinson, M. R., & Monro, T. M. (2015). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015. 2015 Schartner, E. P., Tsiminis, G., Henderson, M. R., Hutchinson, M. R., & Monro, T. M. (2015). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015. 2015 Schartner, E. P., Musolino, S., Salem, A., Hutchinson, M. R., & Monro, T. M. (2015). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Optics InfoBase Conference Papers. 2015 Schartner, E. P., Tsiminis, G., Henderson, M. R., Hutchinson, M. R., & Monro, T. M. (2015). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. In Optics InfoBase Conference Papers. 2014 Maeda, H. (2014). THE EPR EFFECT AND BEYOND FOR CANCER SELECTIVE DRUG DELIVERY FOR TREATMENT AND IMAGING USING NANOMEDICINE. In DRUG METABOLISM REVIEWS Vol. 45 (pp. 15). Toronto, CANADA: INFORMA HEALTHCARE. 2014 Narayan, D., Casson, R. J., Ebneter, A., Chidlow, G., Grace, P. M., Hutchinson, M. R., & Wood, J. P. M. (2014). Immune priming and experimental glaucoma: The effect of prior systemic lipopolysaccharide challenge on tissue outcomes after optic nerve injury. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55 (pp. 7 pages). ASSOC RESEARCH VISION OPHTHALMOLOGY INC. 2007 Hutchinson, M. R., Coats, B. D., Zhang, Y., Lewis, S. S., Sprunger, D. B., Baker, E. M., . . . Watkins, L. R. (2007). Opioid-induced glial activation via a non-classical opioid receptor: clinical implications & the search for the target. In NEURON GLIA BIOLOGY Vol. 2 (pp. S16). CAMBRIDGE UNIV PRESS.
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Conference Items
Year Citation 2020 Ho, R. M., Yin, C. P., Robertson, S. A., Hutchinson, M. L., & Keelan, J. A. (2020). Comparative Effects of TLR4 Inhibitors on Inflammatory Activation in Human Decidual Cells.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG. 2016 Bajic, J. E., Whittaker, A. L., Bobrovskaya, L., Hutchinson, M. R., & Howarth, G. S. (2016). Intestinal mucositis induced by 5-Fluorouracil results in glial changes modified by analgesics via neuro-immune mechanisms. Poster session presented at the meeting of Multinational Association for Supportive Care in Cancer. Adelaide. 2015 Bajic, J., Howarth, G., Eden, G., Lampton, L., Mashtoub, S., & Hutchinson, M. (2015). Intestinal mucositis induced by 5-fluorouracil results in spinal astrocyte expression changes in rats. Poster session presented at the meeting of Journal of Neurochemistry. Cairns, Australia: Wiley.
WoS12014 Bajic, J. E., Howarth, G. S., Eden, G. L., Lampton, L. S., Mashtoub, S., & Hutchinson, M. R. (2014). Intestinal mucositis induced by 5-fluorouracil results in spinal astrocyte expression changes in rats. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Broadbeach, Qld.: Wiley.
2014 Schartner, E., Musolino, S., Salem, A., Hutchinson, M., & Monro, T. (2014). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. Poster session presented at the meeting of Optics InfoBase Conference Papers. 2014 Schartner, E., Tsiminis, G., Henderson, M., Hutchinson, M., & Monro, T. (2014). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. Poster session presented at the meeting of Optics InfoBase Conference Papers. 2014 Li, Y., Coller, J., Hutchinson, M., Klein, K., Zanger, U., Currow, D., . . . Somogyi, A. (2014). Cyp2B6*6 Allele Alters Ketamine'S Pharmacokinetics In Chronic Pain Patients And Metabolism In Vitro. Poster session presented at the meeting of Drug Metabolism Reviews. Toronto, CANADA: Informa Healthcare.
Europe PMC12014 Robertson, S. A., Chin, P. -Y., Dorian, C., & Hutchinson, M. (2014). Inhibition of the TLR4 Signalling Pathway Protects Mice from LPS-Induced Preterm Delivery. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. 2014 Robertson, S. A., Wahid, H. W., Dorian, C., Hutchinson, M., & Olson, D. M. (2014). Toll-Like Receptor 4 (TLR4) Signalling Is Implicated in Normal On-Time Labour in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. 2013 Rolan, P. E., Hutchinson, M. R., Buijs, M., Tuke, J., Kwok, Y. H., Gentgall, M., . . . Nillsen, N. (2013). First demonstration of the neuroimmune link in humans using IV Endotoxin and Intradermal Capsaicin in the face and arm. Poster session presented at the meeting of JOURNAL OF HEADACHE AND PAIN. SPRINGER-VERLAG ITALIA SRL.
2013 Kwiatek, R., Hutchinson, M., Cleland, L., Limaye, V., True, B., Lubhan, C., . . . Coller, J. (2013). GENETIC VARIABILITY IN CYTOKINE AND CYTOKINE RECEPTORS IN FIBROMYALGIA - A PILOT STUDY. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY-BLACKWELL. 2013 Hutchinson, M. R. (2013). THE PROINFLAMMATORY HYPOTHESIS OF ADDICTION: CLINICAL AND PRECLINICAL EVIDENCE.. Poster session presented at the meeting of JOURNAL OF NEUROIMMUNE PHARMACOLOGY. SPRINGER. 2013 Johnson, J., Hutchinson, M., Williams, D., & Rolan, P. (2013). Codeine, Increasing Pain & Medication Overuse Headache: The First Evidence of Codeine-Induced Hyperalgesia. Poster session presented at the meeting of CEPHALALGIA. Boston, MA: SAGE PUBLICATIONS LTD. 2012 Zwicker, J. D., Zhang, Y., Hutchinson, M. R., Rice, K. C., Watkins, L. R., & Funk, G. D. (2012). Microglia attenuate the opioid-induced depression of preBotzinger Complex (preBotC) inspiratory rhythm in vitro via a TLR4-independent pathway. Poster session presented at the meeting of FASEB JOURNAL. San Diego, CA: FEDERATION AMER SOC EXP BIOL.
WoS12012 Narayan, D., Wood, J., Ebneter, A., Chidlow, G., Grace, P., Hutchinson, M., & Casson, R. (2012). IMMUNE PRIMING AND EXPERIMENTAL GLAUCOMA: THE EFFECT OF PRIOR SYSTEMIC LIPOPOLYSACCHARIDE CHALLENGE ON TISSUE OUTCOMES AFTER OPTIC NERVE INJURY. Poster session presented at the meeting of CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. WILEY-BLACKWELL. -
Internet Publications
Year Citation - Morphett, J., Whittaker, A., Reichelt, A., & Hutchinson, M. (n.d.). Perineuronal net structure as a non-cellular mechanism of affective state, a scoping review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols.
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Datasets
Year Citation - Liddicoat, C., Sydnor, H., Cando-Dumancela, C., Dresken, R., Liu, J., Gellie, N., . . . Breed, M. (n.d.). Supporting Data - Naturally-diverse airborne environmental microbial exposures modulate the gut microbiome and may provide anxiolytic benefits in mice.
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Figures
Year Citation - Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Toll-like receptor-4 antagonist (+)-naloxone elicits sexually dimorphic attenuation of inflammation-induced fetal programming in mice. Supplemental Figure 1.
My research program has been funded by the following grant schemes
- DSTG, Centre for Advanced Defence Research and Enterprise – OCE
- DSTG, Defence Science Technology Group - SynBioGen programs
- DSTG, Human Integrated Sensor System Program - Meat and Livestock Australia
- ARC Future Fellowship (FT180100565; Sole CI)
- ARC discovery grant that includes an ARF (DP110100297; Sole CI)
- NHMRC CJ Martin Postdoctoral Fellowship (Sole CI)
- NHMRC project grant (APP1026178; CIB).
- ARC Centre of Excellence for Nanoscale BioPhotonics ($38M, CE140100003)
- NIH R01 grants as a PI (R01 DA034185; R01 DA025978; R01 DA23132; R01 DE017782)
- USA Department of Defence CDMRP grant ($614K)
- National Breast Cancer Foundation of Australia ($112K)
- USA Fibromyalgia Association pilot grant ($55K)
- ~$3M contract research on neuroimmune targeted therapies for pharmaceutical companies such as Phebra, Bionomics, Avigen, Covidien, Implicit Biosciences, NovImmune, Merck and J&J.
I regularly teach into continuing medical education courses for Medical Colleges, Faculties and Societies.
I also teach into several University of Adelaide undergraduate courses as an invited specialist lecturer
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2022 Co-Supervisor Oxidative stress activated prodrugs Master of Philosophy Master Full Time Mr Ravindu Ranasinghe 2022 Principal Supervisor The Human Integrated Sensor System (HISS) Challenge Doctor of Philosophy Doctorate Full Time Mr Michail Laoumtzis 2021 Principal Supervisor Exploring the neurobiological bases of affective states Doctor of Philosophy Doctorate Full Time Ms Jane Cerina Morphett 2021 Principal Supervisor Regulation of the neuro-immune system Doctor of Philosophy Doctorate Full Time Mr Benjamin Daniel Barry 2021 Co-Supervisor Effectiveness of Exercise to Improve Patient-Reported and Central Pain Modulation Outcomes in Chronic Neck Pain Doctor of Philosophy Doctorate Full Time Mr Kexun Kenneth Chen 2021 Principal Supervisor Quantification of the lifetime experience of pain in livestock and its implications on productivity and animal husbandry practices, including applications to human health and wellbeing Doctor of Philosophy Doctorate Full Time Miss Charlotte Helen Johnston 2021 Co-Supervisor Assessing the effects of glycosylation on mu- and delta- opioid receptor function and heteromerization. Master of Philosophy (Medical Science) Master Full Time Miss Kariel Renee Siemens 2021 Co-Supervisor The physiological impacts of virtual fencing on sheep and cattle in South Australia. Doctor of Philosophy Doctorate Part Time Miss Megan Beth Willis 2020 Principal Supervisor Immunophenotyping of Spinal Cord Injured Patients – Advancing Diagnostics and Prognostics. Doctor of Philosophy Doctorate Part Time Mr James Edward Swift 2019 Principal Supervisor Investigating the effects of human mesenchymal stem cells and conditioned media (secretome) for the treatment of pain and neuropathic pain. Doctor of Philosophy Doctorate Full Time Mr Chrysostomos Constantine Maoudis -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2019 - 2019 Principal Supervisor Peripheral-to-Central Neuroimmune Communication and the Sun: Implications for Addiction and Neurodegenerative Disease Pathology Master of Philosophy (Medical Science) Master Full Time Ms Krystal Lee Iacopetta 2018 - 2022 Co-Supervisor Assessing Pain and Treatment Responsiveness in a Patient Cohort and Mouse Model of Inflammatory Arthritis Using Neurobiophotonics Doctor of Philosophy Doctorate Full Time Miss Florence Jade Lees 2016 - 2020 Principal Supervisor The Role of Nitroxyl in the Development of Neuropathic Pain Doctor of Philosophy Doctorate Full Time Mrs Vicky Staikopoulos 2015 - 2020 Principal Supervisor Advanced Preclinical Assessment of Hyper-Nociception Doctor of Philosophy Doctorate Full Time Mr Azim Arman 2015 - 2020 Principal Supervisor Investigation of a Functional Relationship Between Toll-Like Receptor 4 and Transient Receptor Potential Cation Channel Subfamily V Member 1 in Relation to a Novel Neuroimmune Pain Model Doctor of Philosophy Doctorate Full Time Samuel Greig Evans 2014 - 2022 Principal Supervisor Experimental Models of Alcohol Induced Inflammation-associated Depressive-like Behaviour Doctor of Philosophy Doctorate Part Time Joshua Luke Holmes 2014 - 2019 Principal Supervisor From the Bottom Up: Chemotherapy-Induced Gut Toxicity, Glial Reactivity and Cognitive Impairment Doctor of Philosophy Doctorate Part Time Dr Juliana Esma Bajic 2014 - 2017 Principal Supervisor Exploring the Bidirectional Interface between Stress and Innate Immunity: A Focus on Glucocorticoid and TLR4-MyD88 Signalling Doctor of Philosophy Doctorate Full Time Dr Jiajun Liu 2014 - 2019 Co-Supervisor An optical fibre point temperature sensor for investigation of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') induced hyperthermia in the rat brain Doctor of Philosophy Doctorate Full Time Mr Stefan Tyrone Musolino 2014 - 2018 Principal Supervisor Exploring the Role of Spinal Glia and Toll-Like Receptor 4 in the Development of Endometriosis and Neuroimmune-Associated Pain Doctor of Philosophy Doctorate Full Time Kelsi Nicole Dodds 2014 - 2018 Co-Supervisor Investigating the role of Toll-like receptor 4 in myocardial ischaemic-preconditioning and ischaemic-reperfusion injury Doctor of Philosophy Doctorate Full Time Sam Man Lee 2013 - 2017 Co-Supervisor Toll-Like Receptor 4 Signalling in Inflammation Pathways to Term and Preterm Delivery Doctor of Philosophy Doctorate Full Time Miss Hanan Hamimi Binti Wahid 2013 - 2017 Principal Supervisor Exploring the Pharmacology of (+)-Naltrexone on Alcohol Reward and Anxiety Behaviours Doctor of Philosophy Doctorate Full Time Jonathan Henry Jacobsen 2011 - 2017 Principal Supervisor Neuroimmunopharmacology of Opioids Doctor of Philosophy Doctorate Full Time Dr Jacob Henry Lloyd Thomas 2010 - 2014 Co-Supervisor Pharmacogenetics of Ketamine Metabolism and Immunopharmacology of Ketamine Doctor of Philosophy Doctorate Full Time Mr Yibai Li 2010 - 2015 Co-Supervisor Codeine, heightened pain sensitivity and medication overuse headache: A neuroimmune hypothesis and novel treatment strategy. Doctor of Philosophy Doctorate Full Time Miss Jacinta Lee Johnson 2010 - 2015 Principal Supervisor Sex Differences in Allodynia: A complex Interaction Between 17beta-Oestradiol and the Innate Immune System Doctor of Philosophy Doctorate Full Time Miss Lauren Louise Nicotra 2010 - 2015 Co-Supervisor The thermal grill as a tool to investigate analgesic clinical pharmacology Doctor of Philosophy Doctorate Full Time Mrs Nicole Martha Sumracki 2009 - 2011 Co-Supervisor CNS Immune Signalling and Drug Addiction: Role of Interleukin-1 Beta Doctor of Philosophy Doctorate Full Time Mr Liang Liu 2009 - 2014 Co-Supervisor Potential peripheral biomarkers for chronic pain Doctor of Philosophy Doctorate Full Time Miss Yuen Kwok 2008 - 2011 Co-Supervisor The Neuroimmunopharmacology of Alcohol Doctor of Philosophy Doctorate Full Time Miss Yue Wu 2007 - 2011 Co-Supervisor Two methods of biomarker discovery: applications in neuropathic pain and pharmacotherapy Doctor of Philosophy Doctorate Full Time Mr Peter Grace
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Board Memberships
Date Role Board name Institution name Country 2013 - ongoing Board Member Science Technology Australia - Australia -
Memberships
Date Role Membership Country 2012 - ongoing Member Australian Pain Society Australia 2007 - ongoing Member International Association for the Study of Pain United States 2007 - ongoing Member Psychoneuroimmunology Research Society United States 2002 - ongoing Member Society for Neuroscience United States 1999 - ongoing Representative Australasian Society for Clinical and Experimental Pharmacology and Toxicology Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2015 - ongoing Associate Editor Brain, Behavior, and Immunity - -
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External Profiles