Mark Hutchinson

Professor Mark Hutchinson

Director - Centre for Nanoscale BioPhotonics

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Mark Hutchinson is a Professor within the Adelaide Medical School and is the Director of the ARC Centre of Excellence for Nanoscale BioPhotonics.

Professor Hutchinson returned to the University of Adelaide in 2009 as an NHMRC CJ Martin Research Fellow, and established the Neuroimmunopharmacology research laboratory. From 2005 to 2009 Mark worked in the world leading laboratory of Prof Linda Watkins in the Center for Neuroscience at the University of Colorado, Boulder USA. Here he pioneered with Prof Watkins the research which has led to the discovery of a novel drug activity in innate immune receptors.

Mark’s research has implicated the brain immune-like cells in the action of drugs of dependence and the negative side effects of pain treatments.

Mark has published over 100 papers in journals and refereed conference proceedings.

The CNBP is an ARC Centre of Excellence with $38M of funding committed for 7 years, headquartered at The University of Adelaide, with nodes at Macquarie University, Sydney and the RMIT, Melbourne. We are partnered with universities and companies in Europe, the US and China, as well as other  Australian institutions.  

The CNBP has a mission to "Discover new approaches to measure nano-scale  dynamic phenomena in living systems".  

The Scientific Aims of the CNBP are to:  

  1. Reach the limits of light-based measurement within complex and dynamic  biological environments;  
  2. Exploit physics and multiple scales -- nanoscale to macro -- using  photons to bridge from nanomaterial to devices;  
  3. Create smart, tailored interfaces between these nanoscale systems and  the biochemical environment;  
  4. Establish new forms of measurement assays that can operate within  living organisms; 
  5. Deploy these assays to address identified challenges in systems  including the embryo, brain and blood vessels; and  
  6. Seek molecular level insight into the mechanisms, processes and functionalities in these biological systems. 

My research program has been funded by the following grant schemes

  • ARC discovery grant that includes an ARF (DP110100297; Sole CI)
  • NHMRC CJ Martin Postdoctoral Fellowship (Sole CI)
  • NHMRC project grant (APP1026178; CIB).
  • ARC Centre of Excellence for Nanoscale BioPhotonics ($38M, CE140100003)
  • NIH R01 grants as a PI (R01 DA034185; R01 DA025978; R01 DA23132; R01 DE017782)
  • USA Department of Defence CDMRP grant ($614K)
  • National Breast Cancer Foundation of Australia ($112K)
  • USA Fibromyalgia Association pilot grant ($55K)
  • ~$3M contract research on neuroimmune targeted therapies for pharmaceutical companies such as Phebra, Bionomics, Avigen, Covidien, Implicit Biosciences, NovImmune, Merck and J&J.

 

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  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2019 Principal Supervisor Peripheral to Central Communication and the Sun: Implication for Addiction and Disease Pathology Master of Philosophy (Medical Science) Master Full Time Ms Krystal Lee Iacopetta
    2018 Co-Supervisor Assessing Pain and Treatment Responsiveness in a Patient Cohort and Mouse Model of Inflammatory Arthritis Using Neurobiophotonics Doctor of Philosophy Doctorate Full Time Miss Florence Jade Lees
    2016 Principal Supervisor The Role of Nitroxyl (HNO) in Inflammation and Neuropathic Pain signaling Doctor of Philosophy Doctorate Full Time Mrs Vicky Staikopoulos
    2015 Principal Supervisor The Effect of Sex on the Role of TLR4 in Chronic Pain Doctor of Philosophy Doctorate Full Time Samuel Greig Evans
    2015 Principal Supervisor Using Biophotonics to Examine Pain Processing Doctor of Philosophy Doctorate Full Time Mr Azim Arman
    2014 Co-Supervisor MDMA Induced Hyperthermia - The Role of Monocyline on Core Body Temperature Doctor of Philosophy Doctorate Full Time Stefan Musolino
    2014 Principal Supervisor The Interaction Between Stress and Alcohol Induced Neuroinflammation on Depressive-like Behaviour Doctor of Philosophy Doctorate Part Time Joshua Luke Holmes
    2014 Principal Supervisor Assessing Glial Activation in Chemotherapy-Related Cognitive Impairment Doctor of Philosophy Doctorate Part Time Juliana Esma Bajic
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2014 - 2017 Principal Supervisor Exploring the Bidirectional Interface between Stress and Innate Immunity: A Focus on Glucocorticoid and TLR4-MyD88 Signalling Doctor of Philosophy Doctorate Full Time Dr Jiajun Liu
    2014 - 2018 Co-Supervisor Investigating the role of Toll-like receptor 4 in myocardial ischaemic-preconditioning and ischaemic-reperfusion injury Doctor of Philosophy Doctorate Full Time Sam Man Lee
    2014 - 2018 Principal Supervisor Exploring the Role of Spinal Glia and Toll-Like Receptor 4 in the Development of Endometriosis and Neuroimmune-Associated Pain Doctor of Philosophy Doctorate Full Time Kelsi Nicole Dodds
    2013 - 2017 Co-Supervisor Toll-Like Receptor 4 Signalling in Inflammation Pathways to Term and Preterm Delivery Doctor of Philosophy Doctorate Full Time Miss Hanan Hamimi Binti Wahid
    2013 - 2017 Principal Supervisor Exploring the Pharmacology of (+)-Naltrexone on Alcohol Reward and Anxiety Behaviours Doctor of Philosophy Doctorate Full Time Jonathan Henry Jacobsen
    2011 - 2017 Principal Supervisor Neuroimmunopharmacology of Opioids Doctor of Philosophy Doctorate Full Time Dr Jacob Henry Lloyd Thomas
    2010 - 2015 Co-Supervisor The thermal grill as a tool to investigate analgesic clinical pharmacology Doctor of Philosophy Doctorate Full Time Mrs Nicole Martha Sumracki
    2010 - 2014 Co-Supervisor Pharmacogenetics of Ketamine Metabolism and Immunopharmacology of Ketamine Doctor of Philosophy Doctorate Full Time Mr Yibai Li
    2010 - 2015 Principal Supervisor Sex Differences in Allodynia: A complex Interaction Between 17beta-Oestradiol and the Innate Immune System Doctor of Philosophy Doctorate Full Time Miss Lauren Louise Nicotra
    2010 - 2015 Co-Supervisor Codeine, heightened pain sensitivity and medication overuse headache: A neuroimmune hypothesis and novel treatment strategy. Doctor of Philosophy Doctorate Full Time Miss Jacinta Lee Johnson
    2009 - 2014 Co-Supervisor Potential peripheral biomarkers for chronic pain Doctor of Philosophy Doctorate Full Time Miss Yuen Kwok
    2009 - 2011 Co-Supervisor CNS Immune Signalling and Drug Addiction: Role of Interleukin-1 Beta Doctor of Philosophy Doctorate Full Time Mr Liang Liu
    2008 - 2011 Co-Supervisor The Neuroimmunopharmacology of Alcohol Doctor of Philosophy Doctorate Full Time Miss Yue Wu
    2007 - 2011 Co-Supervisor Two methods of biomarker discovery: applications in neuropathic pain and pharmacotherapy Doctor of Philosophy Doctorate Full Time Mr Peter Grace
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  • Board Memberships

    Date Role Board name Institution name Country
    2013 - ongoing Board Member Science Technology Australia Australia
  • Memberships

    Date Role Membership Country
    2012 - ongoing Member Australian Pain Society Australia
    2007 - ongoing Member International Association for the Study of Pain United States
    2007 - ongoing Member Psychoneuroimmunology Research Society United States
    2002 - ongoing Member Society for Neuroscience United States
    1999 - ongoing Representative Australasian Society for Clinical and Experimental Pharmacology and Toxicology Australia
  • Editorial Boards

    Date Role Editorial Board Name Institution Country
    2015 - ongoing Associate Editor Brain, Behavior, and Immunity
  • Position: Director - Centre for Nanoscale BioPhotonics
  • Phone: 83130322
  • Email: mark.hutchinson@adelaide.edu.au
  • Fax: 8224 0685
  • Campus: North Terrace
  • Building: The Braggs, floor 3
  • Room: 3 10
  • Org Unit: Medical Sciences

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