Professor Mark Hutchinson

Interim Director, IPAS

School of Biomedicine

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Prof Mark Hutchinson has been recently appointed as the Interim Director of the Institute for Photonics and Advanced Sensing (IPAS).
As a Professor of Biomedicine and lead the Neuroimmunopharmacology laboratory at the University of Adelaide, Prof Hutchinson has a strong record of leadership of successful teams. His expertise spans diverse basic science methods for human and animal research, including biomarker identification, multiomics and complex data analytics. He has a strong record of engagement with consumers and industry and an advocacy for their involvement in research. Hutchinson has a strong record of commercial translation between basic science and knowledge utilisation.
Prof Hutchinson has diverse leadership and Ministerial appointments, including being a member of the Prime Minister’s National Science and Technology Council, Director of the Australian Research Council Centre of Excellence for Nanoscale BioPhotonics (CNBP), President of the Science and Technology Australia (STA), Members of the ARC Legislative Review, the ARC CEO Advisory Council, and the Australian Economic Accelerator Board. He also serves as the chair of the Safeguarding Australia through Biotechnology Response and Engagement (SABRE) Alliance and is the chair of the Australian Pain Solutions Research Alliance board.
His exceptional leadership of the program of research has been recognised with multiple awards: 2022 Inaugural Coppoc ONE Health Lecture, College of Veterinary Med, Kansas State Uni; 2019 Vice-Chancellor’s Award for Outstanding Achievement – A Culture Of Impact, Uni Adelaide; 2015 James McWha Award of Excellence, Uni Adelaide; 2013 Psychoneuroimmunology Res Soc, Robert Ader Young Investigator Award.

My Research
Career
Publications
Grants and Funding
Teaching
Supervision
Professional Activities
Contact

My research addresses the role of neuroimmune signalling in creating exaggerated pain responses, and the creation of sophisticated tools to quantify pain in humans/animals. This work is internationally renowned and has had broad knowledge and economic impacts. My research that changed understanding of how glial cells (non-neuronal cells in nervous system) modulate immune-signalling in the brain and spinal cord has had major impact on understanding exaggerated sensitivity in painful conditions, their role as treatment targets, and as a target for treatment of addiction. Economic impact demonstrated by 108 patents citing 30 of my papers.

I lead the conception & direction of major research nationally/internationally, including the research of my group. I have been CIA of 3 multidisciplinary NHMRC and ARC Grants (2018-22). My multidisciplinary research team of the CNBP over 9 sites has included 200 staff/students, >100 pubs/yr. Under my leadership, the Centre for Nanoscale BioPhotonics created the bench to boardroom program. Stemming directly from this activity are 19 start-ups and spinouts with more than $500M in collective market capitalisation and demonstrated new market impact value. This represents greater than a 20-fold return on the original investment.

I have obtained >$73M in multiple competitive funding organisations nationally and internationally including NHMRC, ARC, Meat and Livestock Australia, Defence Technology Science Group, NIH, US Drug Authority, DoD (USA). I have published >250 publications with 40% as lead/senior author. I am ranked Top 1% author in ESI filed of Neuroscience and Behaviour. I was invited to present >100 international and >50 national since 2013.

I have several openings for research projects within my team for PhD students

Project 1

Title: Cell-based biomarker of persistent pain in livestock

Description: This project will translate a human biomarker of pain into the livestock setting to predict the chronic pain of animal husbandry practices.

Project available for: HDR and/or Honours

Location: Roseworthy and North Tce

Research Project start date: Semester 1 2023

Special requirements: surgical skills, cell culture experience and some bioinformatics

Project 2

Title: Transcriptome biomarker of persistent pain in livestock

Description: This project will translate a human biomarker of pain into the livestock setting to predict the chronic pain of animal husbandry practices.

Project available for: HDR and/or Honours

Location: Roseworthy and North Tce

Research Project start date: Semester 1 2023

Special requirements: surgical skills, bioinformatics and molecular techniques.

Project 3

Title: Modeling persistent pain in livestock

Description: This project will translate a human model of neuroimmune pain into the livestock setting to better predict the consequences of chronic pain in livestock and allow the development of novel pain therapies.

Project available for: HDR and/or Honours

Location: Roseworthy and North Tce

Research Project start date: Semester 1 2023

Special requirements: surgical skills, animal handling experience and molecular techniques.

Project 4

Title: Drug discovery for novel treatments of persistent pain in livestock

Description: This project will translate neuroimmune pain targeted treatments into the livestock setting to better treat chronic pain in livestock and allow the development of deployable pain therapies.

Project available for: HDR and/or Honours

Location: Roseworthy and North Tce

Research Project start date: Semester 1 2023

Special requirements: surgical skills, animal handling experience and molecular pharmacology techniques.

Appointments

Date	Position	Institution name
2024 - ongoing	Interim Director	The Institute for Photonics and Advanced Sensing (IPAS)
2021 - ongoing	Chair, SABRE Alliance	Defence Science and Technology Group
2021 - 2023	President, Science and Technology Australia	Science and Technology Australia
2014 - ongoing	Director	Australian Research Council Centre of Excellence for Nanoscale BioPhotonics
2014 - ongoing	Professor	University of Adelaide
2014 - 2024	Director and Chief Investigator, ARC Centre of Excellence for Nanoscale BioPhotonics	University of Adelaide
2013 - 2014	Associate Professor	University of Adelaide
2011 - 2012	ARC Research Fellow	University of Adelaide
2009 - 2010	NHMRC CJ Martin Research Fellow	University of Adelaide
2005 - 2008	Postdoc Research Fellow	University of Colorado Boulder

Awards and Achievements

Date	Type	Title	Institution Name	Country	Amount
2022	Award	Inaugural Coppoc ONE Health Lecture	College of Veterinary Medicine	United States	-
2019	Award	Vice Chancellor's Award for Outstanding Achievement - A Culture of Impact	University of Adelaide	Australia	-
2015	Award	The James McWha Award of Excellence	University of Adelaide	Australia	-
2014	Award	Brain Behavior & Immunity Reviewer of the Year	Elsevier	Australia	-
2013	Nomination	South Australian Leading Light Finalist	Australian Society for Medical Research (ASMR)	Australia	-
2013	Award	Robert Ader New Investigator	Psychoneuroimmunology Research Society	-	-
2012	Nomination	Young Researcher Award Finalist	Scopus	-	-
2012	Award	Tess Cramond Lecturer	Australian Pain Society	Australia	-
2011	Award	College on Problems of Drug Abuse Early Career Prize	-	-	-
2010	Award	South Australian Tall Poppy Science Awardee	-	Australia	-
2009	Award	Denis Wade Johnson & Johnson New Investigators	The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT)	-	-
2007	Award	National Institute for Drug Addiction Young Investigator	National Institute for Drug Addiction	Australia	-
2006	Award	Society on Neuroimmune Pharmacology Travel	Society on Neuroimmune Pharmacology	-	-
2005	Award	Oral Presentation Finalist Winner	Front Range Neuroscience Group	-	-
2005	Fellowship	American Australian Association Merck Company Foundation Fellow	American Australian Association Merck Company Foundation	-	-
2005	Nomination	Chapter travel award	Front Range Neuroscience Group	-	-
2005	Award	Chapter oral presentation winner	Front Range Neuroscience Group	-	-
2005	Award	Recipient of a British Council Travel	British Council	-	-
2004	Award	Australian FreshScience Winner	Fresh Science	Australia	-

Education

Date	Institution name	Country	Title
2004	University of Adelaide	Australia	PhD in Medicine
1999	University of Adelaide	Australia	BSc (First class Honours) in Pharmacology
1998	University of Adelaide	Australia	BSc

Research Interests

Basic Pharmacology Clinical Pharmacology and Therapeutics Immunology Innate Immunity Nanomaterials Nanophotonics Nanoscience & Nanotechnology Nanotechnology Neurosciences Pharmacogenomics Pharmacology and Pharmaceutical Sciences Photodetectors, Optical Sensors and Solar Cells Neuroscience, Behaviour and Brain Health Surgical and Health Systems Innovation Pregnancy and Birth Early Origins of Health Immunology and Infection Translational Health Outcomes Innovative Therapeutics

Journals

Year	Citation
2025	Dochnal, S. A., Cohen, S. P., Hutchinson, M. R., Miller, Y. I., & Yaksh, T. L. (2025). Virally-initiated pain states: phenotypes, mechanisms, and future directions. Frontiers in Pain Research, 6, 7 pages. DOI
2025	Bedwell, G. J., Mqadi, L., Parker, R., Chikezie, P. C., Moodley, P., Kamerman, P. R., . . . Madden, V. J. (2025). A systematic review and meta-analysis of pharmacological methods to manipulate experimentally induced secondary hypersensitivity. Pain. DOI
2025	Gilron, I., Xiao, M. Z. X., Carley, M., Salter, M. W., Hutchinson, M. R., Moulin, D. E., . . . Ross-White, A. (2025). Glial-modulating agents for the treatment of pain: a systematic review. Pain, 166(5), 1030-1049. DOI Scopus1 Europe PMC1
2024	Lees, F., Mahbub, S. B., Gosnell, M. E., Campbell, J. M., Weedon, H., Habibalahi, A., . . . Crotti, T. N. (2024). Utilising Hyperspectral Autofluorescence Imaging in the Objective Assessment of Disease State and Pain in Patients with Rheumatoid Arthritis. International Journal of Molecular Sciences, 25(22), 11996-1-11996-15. DOI
2024	Zheng, D., Bhuvan, T., Payne, N. L., Pang, S. H. M., Mendonca, S., Hutchinson, M. R., . . . Heng, T. S. P. (2024). Subcutaneous delivery of mesenchymal stromal cells induces immunoregulatory effects in the lymph node prior to their apoptosis. Stem Cell Research and Therapy, 15(1), 432-1-432-16. DOI Scopus1 Europe PMC1
2024	Siegel, M. A. A., Patetta, M. J. J., Deshpande, A., Orland, M. D. D., & Hutchinson, M. R. R. (2024). Traumatic brain injuries in paediatric patients: individual vs. team sports-related hospitalizations. RESEARCH IN SPORTS MEDICINE, 32(4), 567-579. DOI
2024	Lacagnina, M. J., Willcox, K. F., Boukelmoune, N., Bavencoffe, A., Sankaranarayanan, I., Barratt, D. T., . . . Grace, P. M. (2024). B cells drive neuropathic pain-related behaviors in mice through IgG-Fc gamma receptor signaling. Science Translational Medicine, 16(766), eadj1277-1-eadj1277-14. DOI Scopus5 Europe PMC13
2024	Johnston, C. H., Errington, A. J., Hutchinson, M. R., & Whittaker, A. L. (2024). An Update on Australian Policy around Lamb Marking with Examination of Potential Drivers. Comment on Johnston et al. How Well Does Australian Animal Welfare Policy Reflect Scientific Evidence: A Case Study Approach Based on Lamb Marking. Animals 2023, 13, 1358. Animals, 14(19), 2890-1-2890-19. DOI
2024	Morphett, J. C., Whittaker, A. L., Reichelt, A. C., & Hutchinson, M. R. (2024). Perineuronal net structure as a non-cellular mechanism contributing to affective state: a scoping review. Neuroscience and Biobehavioral Reviews, 158, 105568-1-105568-13. DOI Scopus1 Europe PMC1
2024	Chen, K. K., Rolan, P., Hutchinson, M. R., Dickson, C., & de Zoete, R. M. J. (2024). Exercise-induced changes in central sensitization outcomes in individuals with chronic musculoskeletal pain: A systematic review with meta-analysis. European Journal of Pain, 28(9), 1431-1449. DOI Scopus2 Europe PMC1
2024	Nankivell, V., Vidanapathirana, A. K., Hoogendoorn, A., Tan, J. T. M., Verjans, J., Psaltis, P. J., . . . Bursill, C. A. (2024). Targeting macrophages with multifunctional nanoparticles to detect and prevent atherosclerotic cardiovascular disease. Cardiovascular Research, 120(8), 819-838. DOI Scopus7 Europe PMC5
2024	Hutchinson, M. R., & Hill-Yardin, E. L. (2024). Moving from brain-organ axes to mind-body unity: convergence research by neuroscientists with multi-pronged expertise. Neuroscience, 559, 123-124. DOI Scopus1 Europe PMC1
2024	Rickerby, N. C., Hodges, P. W., Besomi, M., Hutchinson, M. R., & Day, M. A. (2024). Avoiding the Edge Before It Is Too Late: When Is Pain a Sign of Injury in Athletes?. Clinical Journal of Sport Medicine, 34(5), 401-403. DOI
2023	Conigrave, J. H., Devine, E. K., Lee, K. S. K., Dobbins, T., Vnuk, J., Hayman, N., & Conigrave, K. (2023). Unintended consequences: Alcohol screening at urban Aboriginal Community Controlled Health Services was suppressed during COVID-19 lockdowns. Drug and Alcohol Review, 42(7), 1633-1638. DOI Scopus1 Europe PMC2
2023	Smith, L. A., Bem, J. D., Lv, X., Lauto, A., Sliow, A., Ma, Z., . . . Tettamanzi, G. C. (2023). Investigation of the mechanisms for wireless nerve stimulation without active electrodes. Bioelectromagnetics, 44(7-8), 181-191. DOI Europe PMC1
2023	Chalmers, J., Hutchinson, M., Dodds, K., Kwok, Y., Evans, S., & Moseley, L. (2023). Time course of lipopolysaccharide- and capsaicin-induced cytokine release in an ex vivo mouse model of vaginal inflammation. DOI
2023	Zhang, J., Lin, C., Jin, S., Wang, H., Wang, Y., Du, X., . . . Wang, X. (2023). The pharmacology and therapeutic role of cannabidiol in diabetes.. Exploration, 3(5), 10 pages. DOI Scopus12 Europe PMC13
2023	Moseley, G. L., Pearson, N., Reezigt, R., Madden, V. J., Hutchinson, M. R., Dunbar, M., . . . Wand, B. M. (2023). Considering Precision and Utility When we Talk About Pain. Comment on Cohen et al. The Journal of Pain, 24(1), 178-181. DOI Scopus9 WoS5 Europe PMC9
2023	Ryan, M., Tuke, J., Hutchinson, M. R., & Spencer, S. J. (2023). Gender-specific effects of COVID-19 lockdowns on scientific publishing productivity: Impact and resilience. Social Science and Medicine, 320, 115761-1-115761-9. DOI Scopus7 WoS2 Europe PMC3
2023	Mustafa, S., Bajic, J. E., Barry, B., Evans, S., Siemens, K. R., Hutchinson, M. R., & Grace, P. M. (2023). One immune system plays many parts: The dynamic role of the immune system in chronic pain and opioid pharmacology.. Neuropharmacology, 228, 1-14. DOI Scopus11 WoS2 Europe PMC9
2023	Chen, K. K., Hutchinson, M. R., Rolan, P., & de Zoete, R. M. J. (2023). Effect of exercise on chronic neck pain and central sensitization: A protocol for a randomized crossover trial.. Exp Physiol, 108(5), 672-682. DOI Scopus2 Europe PMC3
2023	Moh, E. S. X., Dalal, S., Hutchinson, M. R., & Packer, N. H. (2023). Mouse brain glycomics - Insights from exploring the Allen Brain Atlas and the implications for the neuroimmune brain. Brain, Behavior, and Immunity, 113, 83-90. DOI Scopus2 WoS1
2023	Hill-Yardin, E. L., Hutchinson, M. R., Laycock, R., & Spencer, S. J. (2023). A Chat(GPT) about the future of scientific publishing. Brain, Behavior, and Immunity, 110, 152-154. DOI Scopus173 WoS25 Europe PMC41
2022	Madden, V. J., Msolo, N., Mqadi, L., Lesosky, M., Bedwell, G. J., Hutchinson, M. R., . . . Joska, J. A. (2022). Study protocol: an observational study of distress, immune function and persistent pain in HIV. BMJ Open, 12(6), e059723-1-e059723-10. DOI Europe PMC3
2022	Johnston, C. H., Whittaker, A. L., Franklin, S. H., & Hutchinson, M. R. (2022). The Neuroimmune Interface and Chronic Pain Through the Lens of Production Animals. Frontiers in Neuroscience, 16, 1-16. DOI Scopus6 WoS2 Europe PMC5
2022	Gilron, I., Xiao, M. Z. X., Balanaser, M., Carley, M., Ghasemlou, N., Salter, M. W., . . . Ross-White, A. (2022). Glial-modulating agents for the treatment of pain: protocol for a systematic review. BMJ Open, 12(4), 5 pages. DOI Scopus1 Europe PMC1
2022	Moh, E. S. X., Nishtala, K., Iqbal, S., Staikopoulos, V., Kapur, D., Hutchinson, M. R., & Packer, N. H. (2022). Long-term intrathecal administration of morphine vs. baclofen: differences in CSF glycoconjugate profiles using multiglycomics. Glycobiology, 32(1), 50-59. DOI Scopus8 WoS3 Europe PMC3
2022	Thomas, J. H. L., Lui, L., Abell, A., Tieu, W., Somogyi, A. A., Bajic, J. E., & Hutchinson, M. R. (2022). Toll-Like Receptors change morphine-induced antinociception, tolerance and dependence: studies using male and female TLR and Signalling gene KO mice. Brain, Behavior, and Immunity, 102, 71-85. DOI Scopus14 WoS7 Europe PMC12
2022	Bajic, J., Howarth, G., Mashtoub, S., Whittaker, A., Bobrovskaya, L., & Hutchinson, M. R. (2022). Neuroimmunological complications arising from chemotherapy-induced gut toxicity and opioid exposure in female dark agouti rats. Journal of Neuroscience Research, 100(1), 237-250. DOI Scopus3 WoS3 Europe PMC1
2022	Staikopoulos, V., Zhang, X., Pullen, B. P., Reineck, P., Vidanapathirana, A. K., Lee, S. M., . . . Abell, A. D. (2022). Multi-coloured fluorescent sensing toolbox for selective detection of nitroxyl <i>in vitro</i> and <i>ex vivo</i>. Sensors & Diagnostics, 1(2), 280-293. DOI Scopus1 WoS1
2022	Smith, L. A., Bem, J., Lv, X., Lauto, A., Sliow, A., Ma, Z., . . . Tettamanzi, G. C. (2022). Microscopic Modelling of a Wireless Nerve Stimulator Without Electrodes. DOI
2021	Evans, S. F., Hull, M. L., Hutchinson, M. R., & Rolan, P. E. (2021). Androgens, Endometriosis and Pain.. Frontiers in reproductive health, 3, 7 pages. DOI Scopus9 WoS6 Europe PMC7
2021	Zhang, T., Zhang, X., Lin, C., Wu, S., Wang, F., Wang, H., . . . Wang, X. (2021). Artemisinin inhibits TLR4 signaling by targeting co-receptor MD2 in microglial BV-2 cells and prevents lipopolysaccharide-induced blood–brain barrier leakage in mice. Journal of Neurochemistry, 157(3), 611-623. DOI Scopus20 WoS13 Europe PMC10
2021	Evans, S. F., Kwok, Y., Solterbeck, A., Pyragius, C., Hull, M. L., Hutchinson, M. R., & Rolan, P. (2021). The relationship between androgens and days per month of period pain, pelvic pain, headache, and TLR4 responsiveness of peripheral blood mononuclear cells in young women with dysmenorrhoea. Journal of Pain Research, 14, 585-599. DOI Scopus11 WoS6 Europe PMC9
2021	Li, H., Peng, Y., Lin, C., Zhang, X., Zhang, T., Wang, Y., . . . Wang, X. (2021). Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling. The Innovation, 2(2), 100111-1-100111-8. DOI Scopus17 WoS10 Europe PMC9
2021	Marsh, L., Hutchinson, M., McLaughlan, C., Musolino, S., Hebart, M. L., Terry, R., . . . Whittaker, A. (2021). Evaluation of miRNA as biomarkers of emotional valence in pigs. Animals, 7(7), 1-19. DOI Scopus5 WoS2 Europe PMC3
2021	Lin, C., Wang, H., Zhang, M., Mustafa, S., Wang, Y., Li, H., . . . Wang, X. (2021). TLR4 biased small molecule modulators. Pharmacology and Therapeutics, 228, 107918-1-107918-12. DOI Scopus36 WoS17 Europe PMC27
2021	Williams, B., Lees, F., Tsangari, E., Hutchinson, M. R., Perilli, E., & Crotti, T. N. (2021). Effects of mild and moderate monoclonal antibody dose on inflammation, bone loss, and activation of the central nervous system in a female collagen antibody-induced arthritis mouse model. Journal of Histochemistry and Cytochemistry, 69(8), 511-522. DOI Scopus1 WoS2
2021	Arman, A., & Hutchinson, M. R. (2021). Intrathecal implantation surgical considerations in rodents; a review. Journal of Neuroscience Methods, 363, 109327-1-109327-6. DOI Scopus2 Europe PMC3
2021	Maoudis, C. C., McKinnirey, F., Vesey, G., Blaber, S., & Hutchinson, M. (2021). Mesenchymal Stem Cell Secretome Ameliorates Hyperalgesia in a Post-operative Pain Model. DOI
2021	Gosnell, M. E., Staikopoulos, V., Anwer, A. G., Mahbub, S. B., Hutchinson, M. R., Mustafa, S., & Goldys, E. M. (2021). Autofluorescent imprint of chronic constriction nerve injury identified by deep learning. Neurobiology of Disease, 160, 105528-1-105528-11. DOI Scopus7 WoS1 Europe PMC4
2021	George, R., Semendric, I., Hutchinson, M., & Whittaker, A. (2021). Neuroimmune reactivity marker expression in rodent models of chemotherapy-induced cognitive impairment: a systematic scoping review. Brain, Behavior, and Immunity, 94, 392-409. DOI Scopus16 WoS11 Europe PMC10
2021	Staikopoulos, V., Qiao, S., Liu, J., Song, X., Yang, X., Luo, Q., . . . Zhang, Z. (2021). Graded peripheral nerve injury creates mechanical allodynia proportional to the progression and severity of microglial activity within the spinal cord of male mice. Brain, Behavior, and Immunity, 91, 568-577. DOI Scopus6 WoS3 Europe PMC4
2021	Grace, P. M., Tawfik, V. L., Svensson, C. I., Burton, M. D., Loggia, M. L., & Hutchinson, M. R. (2021). The neuroimmunology of chronic pain: from rodents to humans. The Journal of Neuroscience, 41(5), 855-865. DOI Scopus90 WoS60 Europe PMC67
2021	Ribarovska, A. K., Hutchinson, M. R., Pittman, Q. J., Pariante, C., & Spencer, S. J. (2021). Gender inequality in publishing during the COVID-19 pandemic. Brain, Behavior, and Immunity, 91, 1-3. DOI Scopus60 WoS38 Europe PMC32
2021	Miller, T. L., Jones, G. L., Hutchinson, M., Vyas, D., & Borchers, J. (2021). Evolving Expectations of the Orthopedic Team Physician: Managing the Sidelines and Landmines. Current sports medicine reports, 20(10), 553-561. DOI Scopus2 Europe PMC2
2020	Zabolocki, M., McCormack, K., van den Hurk, M., Milky, B., Shoubridge, A., Adams, R., . . . Bardy, C. (2020). BrainPhys neuronal medium optimized for imaging and optogenetics in vitro. DOI
2020	Doyle, T. M., Largent-Milnes, T. M., Chen, Z., Staikopoulos, V., Esposito, E., Delgarno, R., . . . Salvemini, D. (2020). Chronic morphine-induced changes in signaling at the A3 adenosine receptor contribute to morphine-induced hyperalgesia, tolerance and withdrawal. The Journal of pharmacology and experimental therapeutics, 374(2), 331-341. DOI Scopus32 WoS21 Europe PMC28
2020	Frank, M. G., Baratta, M. V., Zhang, K., Fallon, I. P., Pearson, M. A., Liu, G., . . . Maier, S. F. (2020). Acute stress induces the rapid and transient induction of caspase-1, gasdermin D and release of constitutive IL-1β protein in dorsal hippocampus. Brain, Behavior, and Immunity, 90, 70-80. DOI Scopus12 WoS4 Europe PMC8
2020	Doyle, T. M., Hutchinson, M. R., Braden, K., Janes, K., Staikopoulos, V., Chen, Z., . . . Salvemini, D. (2020). Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents. Journal of Neuroinflammation, 17(1), 8 pages. DOI Scopus8 WoS1 Europe PMC6
2020	Zabolocki, M., McCormack, K., van den Hurk, M., Milky, B., Shoubridge, A. P., Adams, R., . . . Bardy, C. (2020). BrainPhys neuronal medium optimized for imaging and optogenetics in vitro. Nature Communications, 11(1), 1-19. DOI Scopus24 WoS13 Europe PMC19
2020	Evans, S. F., Kwok, Y. H., Solterbeck, A., Liu, J., Hutchinson, M. R., Hull, M. L., & Rolan, P. E. (2020). Toll-like receptor responsiveness of peripheral blood mononuclear cells in young women with dysmenorrhea. Journal of Pain Research, 13, 503-516. DOI Scopus10 WoS5 Europe PMC7
2020	Williams, B., Lees, F., Tsangari, H., Hutchinson, M. R., Perilli, E., & Crotti, T. N. (2020). Assessing the effects of parthenolide on inflammation, bone loss, and glial cells within a collagen antibody-Induced arthritis mouse model. Mediators Inflamm, 2020, 6245798. DOI Scopus17 WoS7 Europe PMC9
2020	Borrachero-Conejo, A. I., Adams, W. R., Saracino, E., Mola, M. G., Wang, M., Posati, T., . . . Benfenati, V. (2020). Stimulation of water and calcium dynamics in astrocytes with pulsed infrared light.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(5), 6539-6553. DOI Scopus31 WoS18 Europe PMC15
2020	Chia, J. S. M., Izham, N. A. M., Farouk, A. A. O., Sulaiman, M. R., Mustafa, S., Hutchinson, M. R., & Perimal, E. K. (2020). Zerumbone Modulates α<inf>2A</inf>-Adrenergic, TRPV1, and NMDA NR2B Receptors Plasticity in CCI-Induced Neuropathic Pain In Vivo and LPS-Induced SH-SY5Y Neuroblastoma In Vitro Models. Frontiers in Pharmacology, 11, 92. DOI Scopus24 WoS15 Europe PMC8
2020	Wang, Y., Zhang, S., Li, H., Wang, H., Zhang, T., Hutchinson, M. R., . . . Wang, X. (2020). Small-molecule modulators of toll-like receptors. Accounts of Chemical Research, 53(3), 1046-1055. DOI Scopus159 WoS96 Europe PMC108
2020	Arman, A., Deng, F., Goldys, E. M., Liu, G., & Hutchinson, M. R. (2020). In vivo intrathecal IL-1β quantification in rats: monitoring the molecular signals of neuropathic pain. Brain, Behavior, and Immunity, 88, 442-450. DOI Scopus18 WoS9 Europe PMC16
2020	Robertson, S. A., Hutchinson, M. R., Rice, K. C., Chin, P. -Y., Moldenhauer, L. M., Stark, M. J., . . . Keelan, J. A. (2020). Targeting Toll-like receptor-4 to tackle preterm birth and fetal inflammatory injury. Clinical and Translational Immunology, 9(4), e1121-1-e1121-19. DOI Scopus41 WoS21 Europe PMC32
2020	Kelley, K. W., Peng, Y. P., Liu, Q., Chang, H. C., Spencer, S. J., Hutchinson, M. R., & Shimada, A. (2020). Psychoneuroimmunology goes East: Development of the PNIRSChina affiliate and its expansion into PNIRSAsia-Pacific. Brain, Behavior, and Immunity, 88, 75-87. DOI Scopus7 WoS4 Europe PMC4
2020	Hutchinson, M. R. (2020). Science convergence applied to psychoneuroimmunology: the future of measurement and imaging. Brain, Behavior, and Immunity, 88, 262-269. DOI Scopus1
2020	Deng, F., Arman, A., Goldys, E. M., Hutchinson, M. R., & Liu, G. (2020). A Method for in Vivo Quantification of Cytokine IL-1β in the Rat Intrathecal Space. ACS Applied Biomaterials, 3(1), 539-546. DOI Scopus11 WoS8 Europe PMC6
2020	Wahid, H. H., Chin, P. Y., Sharkey, D. J., Diener, K. R., Hutchinson, M. R., Rice, K. C., . . . Robertson, S. A. (2020). Toll-like receptor-4 antagonist (+)-naltrexone protects against carbamyl-platelet activating factor (Cpaf)-induced preterm labor in mice. American Journal of Pathology, 190(5), 1030-1045. DOI Scopus15 WoS12 Europe PMC11
2020	Khalid, A., Peng, L., Arman, A., Warren-Smith, S. C., Schartner, E. P., Sylvia, G. M., . . . Li, J. (2020). Silk: a bio-derived coating for optical fiber sensing applications. Sensors and Actuators B: Chemical, 311, 127864-1-127864-8. DOI Scopus24 WoS16
2020	Liddicoat, C., Sydnor, H., Cando-Dumancela, C., Dresken, R., Liu, J., Gellie, N., . . . Breed, M. F. (2020). Naturally-diverse airborne environmental microbial exposures modulate the gut microbiome and may provide anxiolytic benefits in mice. Science of the Total Environment, 701, 1-11. DOI Scopus118 WoS72 Europe PMC63
2020	Iqbal, S., Parker, L. M., Everest-Dass, A., Moh, E. S. X., Sayyadi, N., Hutchinson, M. R., & Packer, N. H. (2020). Lipopolysaccharide and morphine-3-glucuronide-induced immune signalling increases the expression of polysialic acid in PC12 cells. Molecular Neurobiology, 57(2), 964-975. DOI Scopus4 WoS4 Europe PMC2
2020	Iacopetta, K., Collins-Praino, L. E., Buisman-Pijlman, F., Liu, J., Hutchinson, A., & Hutchinson, M. R. (2020). Are the protective benefits of vitamin D in neurodegenerative disease dependent on route of administration? A systematic review. Nutritional Neuroscience, 23(4), 251-280. DOI Scopus16 WoS11 Europe PMC11
2019	Dodds, K., Beckett, E., Evans, S., & Hutchinson, M. (2019). Spinal glial adaptations occur in a minimally invasive mouse model of endometriosis: potential implications for lesion etiology and persistent pelvic pain. Reproductive Sciences, 26(3), 1-13. DOI Scopus20 WoS13 Europe PMC16
2019	Zhang, X., Peng, Y., Grace, P. M., Metcalf, M. D., Kwilasz, A. J., Wang, Y., . . . Wang, X. (2019). Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(8), 9577-9587. DOI Scopus18 WoS11 Europe PMC6
2019	Liu, G., Bursill, C., Cartland, S. P., Anwer, A. G., Parker, L. M., Zhang, K., . . . Goldys, E. M. (2019). A nanoparticle-based affinity sensor that identifies and selects highly cytokine-secreting cells. iScience, 20, 137-147. DOI Scopus16 WoS13 Europe PMC9
2019	Musolino, S. T., Schartner, E. P., Hutchinson, M. R., & Salem, A. (2019). Minocycline attenuates 3,4-methylenedioxymethamphetamine-induced hyperthermia in the rat brain. European Journal of Pharmacology, 858, 172495-1-172495-10. DOI Scopus3 WoS1
2019	Hutchinson, M. R., & Terry, R. (2019). Review: What innovations in pain measurement and control might be possible if we could quantify the neuroimmune synapse?. Animal, 13(12), 3000-3008. DOI Scopus3 WoS2 Europe PMC1
2019	Chin, P. Y., Dorian, C., Sharkey, D. J., Hutchinson, M. R., Rice, K. C., Moldenhauer, L. M., & Robertson, S. A. (2019). Toll-like receptor-4 antagonist (+)-naloxone confers sexually dimorphic protection from inflammation-induced fetal programming in mice. Endocrinology, 160(11), 2646-2662. DOI Scopus16 WoS10 Europe PMC14
2019	Peng, Y., Zhang, X., Zhang, T., Grace, P. M., Li, H., Wang, Y., . . . Wang, X. (2019). Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity, 82, 432-444. DOI Scopus45 WoS34 Europe PMC21
2019	Wang, X., Northcutt, A. L., Cochran, T. A., Zhang, X., Fabisiak, T. J., Haas, M. E., . . . Watkins, L. R. (2019). Methamphetamine activates toll-like receptor 4 to induce central immune signaling within the ventral tegmental area and contributes to extracellular dopamine increase in the nucleus accumbens shell. ACS Chemical Neuroscience, 10(8), 3622-3634. DOI Scopus76 WoS49 Europe PMC57
2019	Zhang, K., Arman, A., Anwer, A., Hutchinson, M., & Goldys, E. (2019). An optical fiber based immunosensor for localized detection of IL-1β in rat spinal cord. Sensors and Actuators, B: Chemical, 282, 122-129. DOI Scopus18 WoS11
2019	Musolino, S. T., Schartner, E. P., Hutchinson, M. R., & Salem, A. (2019). Improved method for optical fiber temperature probe implantation in brains of free-moving rats. Journal of Neuroscience Methods, 313, 24-28. DOI Scopus12 WoS9 Europe PMC4
2019	Parker, L. M., Sayyadi, N., Staikopoulos, V., Shrestha, A., Hutchinson, M. R., & Packer, N. H. (2019). Visualizing neuroinflammation with fluorescence and luminescent lanthanide-based in situ hybridization. Journal of Neuroinflammation, 16(1), 65-1-65-13. DOI Scopus8 WoS6 Europe PMC5
2019	Heng, S., Zhang, X., Pei, J., Adwal, A., Reineck, P., Gibson, B. C., . . . Abell, A. D. (2019). Spiropyran-based nanocarrier: a new Zn²⁺-responsive delivery system with real-time intracellular sensing capabilities. Chemistry - A European Journal, 25(3), 854-862. DOI Scopus17 WoS12 Europe PMC3
2019	Colón, M. R., Hutchinson, M. R., Long, A. M., Voelker, G., & Morrison, M. L. (2019). Postbreeding Habitat Use by Golden-Cheeked Warblers (Setophaga chrysoparia). Western North American Naturalist, 79(3), 337-346. DOI Scopus3 WoS2
2018	Hutchinson, M. R., Stoddart, P. R., & Mahadevan-Jansen, A. (2018). Challenges and opportunities in neurophotonics discussed at the International Conference on Biophotonics 2017. Neurophotonics, 5(4), 1-5. DOI Scopus6 WoS4
2018	Iacopetta, K., Collins-Praino, L., Buisman-Pijlman, F., & Hutchinson, M. (2018). Can neuroimmune mechanisms explain the link between ultraviolet light (UV) exposure and addictive behavior?. Brain, Behavior, and Immunity, 73, 125-132. DOI Scopus4 WoS1 Europe PMC5
2018	Li, J., Ebendorff-Heidepriem, H., Gibson, B., Greentree, A. D., Hutchinson, M., Jia, P., . . . Goldys, E. M. (2018). Perspective: biomedical sensing and imaging with optical fibers - innovation through convergence of science disciplines. APL Photonics, 3(10), 1-20. DOI Scopus39 WoS27
2018	Cao, C., Jin, R., Wei, H., Yang, W., Goldys, E. M., Hutchinson, M. R., . . . Liu, G. (2018). Graphene oxide based recyclable in vivo device for amperometric monitoring of interferon-γ in inflammatory mice. ACS Applied Materials and Interfaces, 10(39), 33078-33087. DOI Scopus25 WoS21 Europe PMC11
2018	Hutchinson, M. R. (2018). GLIA AND PAIN. SCIENTIST, 32(1), 34-41.
2018	Zhang, K., Baratta, M., Liu, G., Frank, M., Leslie, N., Watkins, L., . . . Goldys, E. (2018). A novel platform for in vivo detection of cytokine release within discrete brain regions. Brain, Behavior, and Immunity, 71, 18-22. DOI Scopus29 WoS26 Europe PMC10
2018	Hutchinson, M. R. (2018). ‘Convergence’ created psychoneuroimmunology, and is needed again to secure the future of the field. Brain, Behavior, and Immunity, 71, 1-2. DOI Scopus3 WoS3 Europe PMC2
2018	Bajic, J., Johnston, I., Howarth, G., & Hutchinson, M. (2018). From the bottom-up: chemotherapy and gut-brain axis dysregulation. Frontiers in Behavioral Neuroscience, 12, 104-1-104-16. DOI Scopus78 WoS54 Europe PMC61
2018	Hutchinson, M. (2018). The importance of knowing you are sick: nanoscale biophotonics for the 'other' brain. Microelectronic Engineering, 187-188, 101-104. DOI Scopus4 WoS4
2018	Marcu, L., Boppart, S., Hutchinson, M., Popp, J., & Wilson, B. (2018). Biophotonics: The big picture. Journal of Biomedical Optics, 23(2), 1-7. DOI Scopus26 WoS19 Europe PMC12
2018	Hutchinson, M. R. (2018). Glial ties to persistent pain : Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain. Scientist, 32(1), 34-41.
2018	Liu, J., Mustafa, S., Barratt, D., & Hutchinson, M. (2018). Corticosterone preexposure increases NF-κB translocation and sensitizes IL-1β responses in BV2 microglia-like cells. Frontiers in Immunology, 9(JAN), 1-12. DOI Scopus22 WoS15 Europe PMC14
2018	Robertson, S. A., Wahid, H. H., Chin, P. Y., Hutchinson, M. R., Moldenhauer, L. M., & Keelan, J. A. (2018). Toll-like receptor-4: A new target for preterm labour pharmacotherapies?. Current Pharmaceutical Design, 24(9), 960-973. DOI Scopus17 WoS17 Europe PMC12
2018	Zhang, X., Cui, F., Chen, H., Zhang, T., Yang, K., Wang, Y., . . . Wang, X. (2018). Dissecting the innate immune recognition of opioid inactive isomer (+)-naltrexone derived toll-like receptor 4 (TLR4) antagonists. Journal of Chemical Information and Modeling, 58(4), 816-825. DOI Scopus39 WoS29 Europe PMC26
2018	Beckett, E., Staikopoulos, V., & Hutchinson, M. (2018). Differential effect of morphine on gastrointestinal transit, colonic contractions and nerve-evoked relaxations in Toll-Like Receptor deficient mice. Scientific Reports, 8(1), 5923-1-5923-13. DOI Scopus14 WoS10 Europe PMC14
2018	Jacobsen, J., Buisman-Pijlman, F., Mustafa, S., Rice, K., & Hutchinson, M. (2018). The efficacy of (+)-Naltrexone on alcohol preference and seeking behaviour is dependent on light-cycle. Brain, Behavior, and Immunity, 67, 181-193. DOI Scopus9 WoS8 Europe PMC8
2018	Jacobsen, J., Buisman-Pijlman, F., Mustafa, S., Rice, K., & Hutchinson, M. (2018). Antagonising TLR4-TRIF signalling before or after a low-dose alcohol binge during adolescence prevents alcohol drinking but not seeking behaviour in adulthood. Neuropharmacology, 128, 460-473. DOI Scopus13 WoS9 Europe PMC12
2017	Liu, G., Zhang, K., Nadort, A., Hutchinson, M., & Goldys, E. (2017). Sensitive cytokine assay based on optical fiber allowing localized and spatially resolved detection of interleukin-6. ACS Sensors, 2(2), 218-226. DOI Scopus43 WoS35 Europe PMC15
2017	Dodds, K. N., Beckett, E. A., Evans, S. F., & Hutchinson, M. R. (2017). Lesion development is modulated by the natural estrous cycle and mouse strain in a minimally invasive model of endometriosis. Biology of Reproduction, 97(6), 810-821. DOI Scopus22 WoS14 Europe PMC15
2017	Zohora, N., Kandjani, A., Orth, A., Brown, H., Hutchinson, M., & Gibson, B. (2017). Fluorescence brightness and photostability of individual copper (I) oxide nanocubes. Scientific Reports, 7(1), 16905-1-16905-8. DOI Scopus6 WoS3 Europe PMC2
2017	Tsiminis, G., Schartner, E., Brooks, J., & Hutchinson, M. (2017). Measuring and tracking vitamin B12: a review of current methods with a focus on optical spectroscopy. Applied Spectroscopy Reviews, 52(5), 439-455. DOI Scopus30 WoS17
2017	Johnston, I., Tan, M., Cao, J., Matsos, A., Forrest, D., Si, E., . . . Hutchinson, M. (2017). Ibudilast reduces oxaliplatin-induced tactile allodynia and cognitive impairments in rats. Behavioural Brain Research, 334, 109-118. DOI Scopus23 WoS19 Europe PMC14
2017	Liu, G., Zhang, K., Ma, K., Care, A., Hutchinson, M., & Goldys, E. (2017). Graphene quantum dot based "switch-on" nanosensors for intracellular cytokine monitoring. Nanoscale, 9(15), 4934-4943. DOI Scopus38 WoS30 Europe PMC6
2017	Lewis, S., Grace, P., Hutchinson, M., Maier, S., & Watkins, L. (2017). Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia. Brain, Behavior, and Immunity, 64, 59-64. DOI Scopus3 WoS2 Europe PMC3
2016	Jacobsen, J., Parker, L., Everest-Dass, A., Schartner, E., Tsiminis, G., Staikopoulos, V., . . . Mustafa, S. (2016). Novel imaging tools for investigating the role of immune signalling in the brain. Brain, Behavior, and Immunity, 58, 40-47. DOI Scopus12 WoS11 Europe PMC4
2016	Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Coller, J., White, I., . . . Bowen, J. (2016). Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms. Molecular Cancer Therapeutics, 15(6), 1376-1386. DOI Scopus113 WoS82 Europe PMC79
2016	Lee, S., Hutchinson, M., & Saint, D. (2016). The role of Toll-like receptor 4 (TLR4) in cardiac ischaemic-reperfusion injury, cardioprotection and preconditioning. Clinical and Experimental Pharmacology and Physiology, 43(9), 864-871. DOI Scopus30 WoS26 Europe PMC22
2016	Chalmers, K., Madden, V., Hutchinson, M., & Moseley, G. (2016). Local and systemic inflammation in localized, provoked vestibulodynia. Obstetrics and Gynecology, 128(2), 337-347. DOI Scopus20 WoS12 Europe PMC11
2016	Musolino, S., Schartner, E., Tsiminis, G., Salem, A., Monro, T., & Hutchinson, M. (2016). Portable optical fiber probe for in vivo brain temperature measurements. Biomedical Optics Express, 7(8), 3069-3078. DOI Scopus67 WoS48 Europe PMC12
2016	Ellis, A., Grace, P., Wieseler, J., Favret, J., Springer, K., Skarda, B., . . . Watkins, L. (2016). Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury. Brain, Behavior, and Immunity, 58, 348-356. DOI Scopus67 WoS49 Europe PMC51
2016	Dodds, K., Beckett, E., Evans, S., Grace, P., Watkins, L., & Hutchinson, M. (2016). Glial contributions to visceral pain : implications for disease etiology and the female predominance of persistent pain. Translational Psychiatry, 6(9), e888-1-e888-13. DOI Scopus49 WoS41 Europe PMC37
2016	Somogyi, A., Sia, A., Tan, E., Coller, J., Hutchinson, M., & Barratt, D. (2016). Ethnicity-dependent influence of innate immune genetic markers on morphine PCA requirements and adverse effects in postoperative pain. Pain, 157(11), 2458-2466. DOI Scopus25 WoS18 Europe PMC16
2016	Chin, P., Dorian, C., Hutchinson, M., Olson, D., Rice, K., Moldenhauer, L., & Robertson, S. (2016). Novel Toll-like receptor-4 antagonist (+)-naloxone protects mice from inflammation-induced preterm birth. Scientific Reports, 6(1), 36112-1-36112-13. DOI Scopus61 WoS52 Europe PMC45
2016	Grace, P., Gaudet, A., Staikopoulos, V., Maier, S., Hutchinson, M., Salvemini, D., & Watkins, L. (2016). Nitroxidative signaling mechanisms in pathological pain. Trends in Neurosciences, 39(12), 862-879. DOI Scopus94 WoS80 Europe PMC66
2016	Gibson, R., Coller, J., Wardill, H., Hutchinson, M., Smid, S., & Bowen, J. (2016). Chemotherapy-induced gut toxicity and pain: involvement of TLRs. Supportive Care in Cancer, 24(5), 2251-2258. DOI Scopus21 WoS20 Europe PMC14
2016	Wang, X., Zhang, Y., Peng, Y., Hutchinson, M., Rice, K., Yin, H., & Watkins, L. (2016). Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4. British Journal of Pharmacology, 173(5), 856-869. DOI Scopus139 WoS102 Europe PMC101
2016	Jacobsen, J., Hutchinson, M., & Mustafa, S. (2016). Drug addiction: targeting dynamic neuroimmune receptor interactions as a potential therapeutic strategy. Current Opinion in Pharmacology, 26, 131-137. DOI Scopus24 WoS25 Europe PMC21
2016	Liu, G., Qi, M., Hutchinson, M., Yang, G., & Goldys, E. (2016). Recent advances in cytokine detection by immunosensing. Biosensors and Bioelectronics, 79, 810-821. DOI Scopus125 WoS98 Europe PMC58
2016	Mao, J., Tang, D., Bao, S., Luo, L., & Gao, Z. (2016). High temperature strength and multiaxial fatigue life assessment of a tubesheet structure. ENGINEERING FAILURE ANALYSIS, 68, 10-21. DOI
2015	Ingman, W., Glynn, D., & Hutchinson, M. (2015). Mouse models of mastitis - how physiological are they?. International Breastfeeding Journal, 10(1), 12-1-12-5. DOI Scopus17 WoS14 Europe PMC15
2015	Lee, S., Hutchinson, M., Staikopoulos, V., & Saint, D. (2015). Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injury. International Journal of Cardiology, 190, 353-359. DOI Scopus10 WoS8 Europe PMC6
2015	Wahid, H., Dorian, C., Chin, P., Hutchinson, M., Rice, K., Olson, D., . . . Robertson, S. (2015). Toll-like receptor 4 Is an essential upstream regulator of on-time parturition and perinatal viability in mice. Endocrinology, 156(10), 3828-3841. DOI Scopus59 WoS48 Europe PMC41
2015	Bachtell, R., Hutchinson, M., Wang, X., Rice, K., Maier, S., & Watkins, L. (2015). Targeting the toll of drug abuse: the translational potential of toll-like receptor 4. CNS and Neurological Disorders - Drug Targets, 14(6), 692-699. DOI Scopus77 WoS58 Europe PMC59
2015	Johnson, J. L., Kwok, Y. H., Sumracki, N. M., Swift, J. E., Hutchinson, M. R., Johnson, K., . . . Rolan, P. E. (2015). Glial attenuation with ibudilast in the treatment of medication overuse headache: a double-blind, randomized, placebo-controlled pilot trial of efficacy and safety. Headache, 55(9), 1192-1208. DOI Scopus18 WoS13 Europe PMC13
2015	Corrigan, F., Wu, Y., Tuke, J., Coller, J., Rice, K., Diener, K., . . . Hutchinson, M. (2015). Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling. Brain, Behavior, and Immunity, 45, 245-252. DOI Scopus22 WoS17 Europe PMC20
2015	Northcutt, A., Hutchinson, M., Wang, X., Baratta, M., Hiranita, T., Cochran, T., . . . Watkins, L. (2015). DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Molecular Psychiatry, 20(12), 1525-1537. DOI Scopus189 WoS149 Europe PMC143
2015	Li, Y., Jackson, K., Slon, B., Hardy, J., Franco, M., William, L., . . . Somogyi, A. (2015). CYP2B66 allele and age substantially reduce steady-state ketamine clearance in chronic pain patients: impact on adverse effects. British Journal of Clinical Pharmacology*, 80(2), 276-284. DOI Scopus54 WoS37 Europe PMC37
2015	Lewis, S., Hutchinson, M., Frick, M., Zhang, Y., Maier, S., Sammakia, T., . . . Watkins, L. (2015). Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain. Brain, Behavior, and Immunity, 44, 128-136. DOI Scopus14 WoS12 Europe PMC12
2014	Liu, J., Buisman-Pijlman, F., & Hutchinson, M. (2014). Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder. Frontiers in Neuroscience, 8(SEP), 309-1-309-15. DOI Scopus100 WoS73 Europe PMC67
2014	Jacobsen, J., Watkins, L., & Hutchinson, M. (2014). Discovery of a novel site of opioid action at the innate immune pattern-recognition receptor TLR4 and its role in addiction. International Review of Neurobiology, 118, 129-163. DOI Scopus57 WoS42 Europe PMC50
2014	Hutchinson, M. R. (2014). Want more pain? Just add a dash of endotoxin to enhance your clinical pain model. Brain, Behavior, and Immunity, 41(1), 44-45. DOI Scopus9 WoS7 Europe PMC7
2014	Watkins, L. R., & Hutchinson, M. R. (2014). A concern on comparing 'apples' and 'oranges' when differences between microglia used in human and rodent studies go far, far beyond simply species: Comment on Smith and Dragunow. Trends in Neurosciences, 37(4), 189-190. DOI Scopus12 WoS9 Europe PMC9
2014	Johnson, J., Rolan, P., Johnson, M., Bobrovskaya, L., Williams, D., Johnson, K., . . . Hutchinson, M. (2014). Codeine-induced hyperalgesia and allodynia: investigating the role of glial activation. Translational Psychiatry, 4(11), e482-1-e482-9. DOI Scopus32 WoS28 Europe PMC28
2014	Grace, P., Ramos, K., Rodgers, K., Wang, X., Hutchinson, M., Lewis, M., . . . Watkins, L. (2014). Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience, 280, 299-317. DOI Scopus57 WoS51 Europe PMC46
2014	Nicotra, L., Tuke, S., Grace, P., Rolan, P., & Hutchinson, M. (2014). Sex differences in mechanical allodynia: how can it be preclinically quantified and analyzed?. Frontiers in Behavioral Neuroscience, 8(February), 1-16. DOI Scopus43 WoS33 Europe PMC32
2014	Sumracki, N., Buisman-Pijlman, F., Hutchinson, M., Gentgall, M., & Rolan, P. (2014). Reduced response to the thermal grill illusion in chronic pain patients. Pain Medicine, 15(4), 647-660. DOI Scopus19 WoS14 Europe PMC11
2014	Narayan, D., Casson, R., Ebneter, A., Chidlow, G., Grace, P., Hutchinson, M., & Wood, J. (2014). Immune priming and experimental glaucoma: the effect of prior systemic lipopolysaccharide challenge on tissue outcomes after optic nerve injury. Clinical and Experimental Ophthalmology, 42(6), 539-554. DOI Scopus7 WoS2 Europe PMC4
2014	Glynn, D., Hutchinson, M., & Ingman, W. (2014). Toll-like receptor 4 regulates lipopolysaccharide-induced inflammation and lactation insufficiency in a mouse model of mastitis. Biology of Reproduction, 90(5), 1-11. DOI Scopus28 WoS24 Europe PMC22
2014	Grace, P., Hutchinson, M., Maier, S., & Watkins, L. (2014). Pathological pain and the neuroimmune interface. Nature Reviews Immunology, 14(4), 217-231. DOI Scopus720 WoS590 Europe PMC542
2014	Watkins, L. R., Wang, X., Mustafa, S., & Hutchinson, M. R. (2014). In vivo veritas: (+)-Naltrexone's actions define translational importance. A letter in response to Skolnick et al. 'Translational potential of naloxone and naltrexone as TLR4 antagonists'. Trends in Pharmacological Sciences, 35(9), 432-433. DOI Scopus15 WoS14 Europe PMC12
2014	Ingman, W., Glynn, D., & Hutchinson, M. (2014). Inflammatory mediators in mastitis and lactation insufficiency. Journal of Mammary Gland Biology and Neoplasia, 19(2), 161-167. DOI Scopus59 WoS49 Europe PMC44
2014	Zwicker, J., Zhang, Y., Ren, J., Hutchinson, M., Rice, K., Watkins, L., . . . Funk, G. (2014). Glial TLR4 signaling does not contribute to opioid-induced depression of respiration. Journal of Applied Physiology, 117(8), 857-868. DOI Scopus15 WoS11 Europe PMC11
2014	Mulholland, C., Somogyi, A., Barratt, D., Coller, J., Hutchinson, M., Jacobson, G., . . . Sleigh, J. (2014). Association of innate immune single-nucleotide polymorphisms with the electroencephalogram during desflurane general anaesthesia. Journal of Molecular Neuroscience, 52(4), 497-506. DOI Scopus17 WoS11 Europe PMC10
2014	Hutchinson, M., & Watkins, L. (2014). Why is neuroimmunopharmacology crucial for the future of addiction research?. Neuropharmacology, 76(Part B), 218-227. DOI Scopus82 WoS75 Europe PMC67
2014	Stewart, L. R., Morrison, M. L., Hutchinson, M. R., Appel, D. N., & Wilkins, R. N. (2014). Effects of a forest pathogen on habitat selection and quality for the endangered golden-cheeked warbler. Wildlife Society Bulletin, 38(2), 279-287. DOI Scopus13 WoS12
2013	Thomas, J., & Hutchinson, M. R. (2013). Erratum: Exploring neuroinflammation as a potential avenue to improve the clinical efficacy of opioids (Expert Review of Neurotherapeutics (2012) 12:11 (1311-1324)). Expert Review of Neurotherapeutics, 13(3), 339-340. DOI
2013	Thomas, J., & Hutchinson, M. R. (2013). Exploring neuroinflammation as a potential avenue to improve the clinical efficacy of opioids (vol 12, pg 1311, 2012). EXPERT REVIEW OF NEUROTHERAPEUTICS, 13(3), 339-340.
2013	Kwok, Y., Tuke, S., Nicotra, L., Grace, P., Rolan, P., & Hutchinson, M. (2013). TLR 2 and 4 responsiveness from isolated peripheral blood mononuclear cells from rats and humans as potential chronic pain biomarkers. PLoS One, 8(10), 1-16. DOI Scopus20 WoS16 Europe PMC18
2013	Della Vedova, C., Cathcart, S., Dohnalek, A., Lee, V., Hutchinson, M., Immink, M., & Hayball, J. (2013). Peripheral interleukin-1β levels are elevated in chronic tension-type headache patients. Pain Research & Management : The Journal of the Canadian Pain Society = journal de la société canadienne pour le traitement de la douleur, 18(6), 301-306. DOI Scopus35 WoS22 Europe PMC24
2013	Li, Y., Coller, J., Hutchinson, M., Klein, K., Zanger, U., Stanley, N., . . . Somogyi, A. (2013). The CYP2B66 allele significantly alters the N-demethylation of ketamine enantiomers in vitro. Drug Metabolism and Disposition*, 41(6), 1264-1272. DOI Scopus41 WoS34 Europe PMC25
2013	Hutchinson, M., Bujis, M., Tuke, S., Kwok, Y., Gentgall, M., Williams, D., & Rolan, P. (2013). Low-dose endotoxin potentiates capsaicin-induced pain in man: evidence for a pain neuroimmune connection. Brain Behavior and Immunity, 30, 3-11. DOI Scopus58 WoS47 Europe PMC43
2013	Theberge, F., Li, X., Kambhampati, S., Pickens, C., St Laurent, R., Bossert, J., . . . Shaham, Y. (2013). Effect of chronic delivery of the toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving. Biological Psychiatry, 73(8), 729-737. DOI Scopus107 WoS89 Europe PMC94
2013	Lewis, S., Hutchinson, M., Zhang, Y., Hund, D., Maier, S., Rice, K., & Watkins, L. (2013). Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain. Brain Behavior and Immunity, 30, 24-32. DOI Scopus56 WoS44 Europe PMC47
2013	Johnson, J., Hutchinson, M., Williams, D., & Rolan, P. (2013). Medication-overuse headache and opioid-induced hyperalgesia: A review of mechanisms, a neuroimmune hypothesis and a novel approach to treatment. Cephalalgia, 33(1), 52-64. DOI Scopus43 WoS35 Europe PMC29
2012	Jalleh, R., Koh, K., Choi, B., Liu, E., Maddison, J., & Hutchinson, M. (2012). Role of microglia and toll-like receptor 4 in the pathophysiology of delirium. Medical Hypotheses, 79(6), 735-739. DOI Scopus22 WoS17 Europe PMC15
2012	Kwok, Y., Hutchinson, M., Gentgall, M., & Rolan, P. (2012). Increased responsiveness of peripheral blood mononuclear cells to in vitro TLR 2, 4 and 7 ligand stimulation in chronic pain patients. PLoS One, 7(8), 1-8. DOI Scopus47 WoS41 Europe PMC42
2012	Hutchinson, M., Northcutt, A., Hiranita, T., Wang, X., Lewis, S., Thomas, J., . . . Watkins, L. (2012). Opioid activation of toll-like receptor 4 contributes to drug reinforcement. Journal of Neuroscience, 32(33), 11187-11200. DOI Scopus245 WoS198 Europe PMC191
2012	Grace, P., Hurley, D., Barratt, D., Tsykin, A., Watkins, L., Rolan, P., & Hutchinson, M. (2012). Harnessing pain heterogeneity and RNA transcriptome to idenitfy blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic construction injury model. Journal of Neurochemistry, 122(5), 976-994. DOI Scopus23 WoS22 Europe PMC18
2012	Watkins, L., Hutchinson, M., & Johnson, K. (2012). Commentary on Landry et al.: "Propentofylline, a CNS glial modulator, does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages". Experimental Neurology, 234(2), 351-353. DOI Scopus19 WoS17 Europe PMC18
2012	Corrigan, F., & Hutchinson, M. (2012). Are the effects of alcohol on the CNS influenced by Toll-like receptor signaling?. Expert Review of Clinical Immunology, 8(3), 201-203. DOI Scopus6 WoS4 Europe PMC3
2012	Sumracki, N., Hutchinson, M., Gentgall, M., Briggs, N., Williams, D., & Rolan, P. (2012). The effects of pregabalin and the glial attenuator minocycline on the response to intradermal capsaicin in patients with unilateral sciatica. PLoS One, 7(6), 1-8. DOI Scopus20 WoS18 Europe PMC15
2012	Lewis, S., Loram, L., Hutchinson, M., Li, C., Zhang, Y., Maier, S., . . . Watkins, L. (2012). (+)-Naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats. The Journal of Pain, 13(5), 498-506. DOI Scopus89 WoS77 Europe PMC72
2012	Wang, X., Loram, L., Ramos, K., de Jesus, A., Thomas, J., Cheng, K., . . . Yin, H. (2012). Morphine activates neuroinflammation in a manner parallel to endotoxin. Proceedings of the National Academy of Sciences of the United States of America, 109(16), 6325-6330. DOI Scopus396 WoS332 Europe PMC310
2012	Coller, J., & Hutchinson, M. (2012). Implications of central immune signaling caused by drugs of abuse: Mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence. Pharmacology & Therapeutics, 134(2), 219-245. DOI Scopus156 WoS129 Europe PMC126
2012	Nicotra, L., Loram, L., Watkins, L., & Hutchinson, M. (2012). Toll-like receptors in chronic pain. Experimental Neurology, 234(2), 316-329. DOI Scopus221 WoS177 Europe PMC161
2012	Wu, Y., Lousberg, E., Moldenhauer, L., Hayball, J., Coller, J., Rice, K., . . . Hutchinson, M. (2012). Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. British Journal of Pharmacology, 165(5), 1319-1329. DOI Scopus68 WoS57 Europe PMC56
2012	Thomas, J., & Hutchinson, M. (2012). Exploring neuroinflammation as a potential avenue to improve the clinical efficacy of opioids. Expert Review of Neurotherapeutics, 12(11), 1311-1324. DOI Scopus13 WoS10 Europe PMC11
2011	Schwarz, J., Hutchinson, M., & Bilbo, S. (2011). Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. The Journal of Neuroscience, 31(49), 17835-17847. DOI Scopus164 WoS139 Europe PMC144
2011	Anderson, P., Hutchinson, M., Irvine, R., & Salem, A. (2011). Attenuating glial activation with minocycline reduces the hyperthermic response to 3, 4-methylenedioxymethamphetamine (MDMA) in the rat. The Open Addiction Journal, 4(Sp Iss), 4-5. DOI
2011	Salem, A., Gordon, J., Hutchinson, M., & Irvine, R. (2011). 3,4-Methylenedioxymethamphetamine (MDMA) induced hyperthermia - the role of pro-inflammatory cytokines. The Open Addiction Journal, 4(Sp Iss), 48-49. DOI
2011	Grace, P., Rolan, P., & Hutchinson, M. (2011). Peripheral immune contributions to the maintenance of central glial activation underlying neuropathic pain. Brain Behavior and Immunity, 25(7), 1322-1332. DOI Scopus96 WoS84 Europe PMC81
2011	Liu, L., Ghosh, N., Slivka, P., Fiorini, Z., Hutchinson, M., Watkins, L., & Yin, H. (2011). An MD2 hot-spot-mimicking peptide that suppresses TLR4-mediated inflammatory response in vitro and in vivo. ChemBioChem, 12(12), 1827-1831. DOI Scopus14 WoS13 Europe PMC10
2011	Liu, L., Coller, J., Watkins, L., Somogyi, A., & Hutchinson, M. (2011). Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: Comparison of different mouse strains. Brain Behavior and Immunity, 25(6), 1223-1232. DOI Scopus54 WoS47 Europe PMC46
2011	Hutchinson, M., Shavit, Y., Grace, P., Rice, K., Maier, S., & Watkins, L. (2011). Exploring the neuroimmunopharmacology of opioids: An integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacological Reviews, 63(3), 772-810. DOI Scopus335 WoS289 Europe PMC253
2011	Wu, Y., Lousberg, E., Moldenhauer, L., Hayball, J., Robertson, S., Coller, J., . . . Hutchinson, M. (2011). Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment. Brain Behavior and Immunity, 25(Suppl 1), 155-164. DOI Scopus70 WoS52 Europe PMC53
2011	Grace, P., Hutchinson, M., Bishop, A., Somogyi, A., Mayrhofer, G., & Rolan, P. (2011). Adoptive transfer of peripheral immune cells potentiates allodynia in a graded chronic constriction injury model of neuropathic pain. Brain Behavior and Immunity, 25(3), 503-513. DOI Scopus24 WoS21 Europe PMC21
2010	Grace, P., Hutchinson, M., Manavis, J., Somogyi, A., & Rolan, P. (2010). A novel animal model of graded neuropathic pain: Utility to investigate mechanisms of population heterogeneity. Journal of Neuroscience Methods, 193(1), 47-53. DOI Scopus45 WoS39 Europe PMC39
2010	Joce, C., Stahl, J., Shridhar, M., Hutchinson, M., Watkins, L., Fedichev, P., & Yin, H. (2010). Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions. Bioorganic & Medicinal Chemistry Letters, 20(18), 5411-5413. DOI Scopus34 WoS32 Europe PMC28
2010	Stanley, N., Hutchinson, M., Kvist, T., Nielsen, B., Mathiesen, J., Brauner-Osborne, H., . . . Taylor, D. (2010). A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity. Bioorganic & Medicinal Chemistry, 18(16), 6089-6098. DOI Scopus6 WoS4
2010	Buchanan, M., Hutchinson, M., Watkins, L., & Yin, H. (2010). Toll-like receptor 4 in CNS pathologies. Journal of Neurochemistry, 114(1), 13-27. DOI Scopus298 WoS266 Europe PMC227
2010	Hutchinson, M., Zhang, Y., Shridhar, M., Evans, J., Buchanan, M., Zhao, T., . . . Watkins, L. (2010). Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behavior and Immunity, 24(1), 83-95. DOI Scopus447 WoS371 Europe PMC360
2010	Lewis, S., Hutchinson, M., Rezvani, N., Loram, L., Zhang, Y., Maier, S., . . . Watkins, L. (2010). Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta. Neuroscience, 165(2), 569-583. DOI Scopus153 WoS129 Europe PMC117
2010	Hutchinson, M., Loram, L., Zhang, Y., Shridhar, M., Rezvani, N., Berkelhammer, D., . . . Watkins, L. (2010). Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience, 168(2), 551-563. DOI Scopus86 WoS68 Europe PMC60
2010	Hutchinson, M., Lewis, S., Coats, B., Rezvani, N., Zhang, Y., Wieseler, J., . . . Watkins, L. (2010). Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences. Neuroscience, 167(3), 880-893. DOI Scopus114 WoS95 Europe PMC99
2009	Slivka, P., Shridhar, M., Lee, G., Sammond, D., Hutchinson, M., Martinko, A., . . . Yin, H. (2009). A Peptide Antagonist of the TLR4-MD2 Interaction. ChemBioChem, 10(4), 645-649. DOI Scopus41 WoS40 Europe PMC31
2009	Rolan, P., Hutchinson, M., & Johnson, K. (2009). Ibudilast: a review of its pharmacology, efficacy and safety in respiratory and neurological disease. Expert Opinion on Pharmacotherapy, 10(17), 2897-2904. DOI Scopus134 WoS108 Europe PMC92
2009	Hutchinson, M., Ramos, K., Loram, L., Wieseler-Frank, J., Sholar, P., Kearney, J., . . . Watkins, L. (2009). Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience, 164(4), 1821-1832. DOI Scopus71 WoS60 Europe PMC58
2009	Loram, L., Harrison, J., Sloane, E., Hutchinson, M., Sholar, P., Taylor, F., . . . Watkins, L. (2009). Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: A novel therapy for neuropathic pain. Journal of Neuroscience, 29(44), 14015-14025. DOI Scopus97 WoS79 Europe PMC73
2009	Liu, L., Hutchinson, M., White, J., Somogyi, A., & Coller, J. (2009). Association of IL-1B genetic polymorphisms with an increased risk of opioid and alcohol dependence. Pharmacogenetics and Genomics (Print Edition), 19(11), 869-876. DOI Scopus42 WoS36 Europe PMC35
2009	Watkins, L., Hutchinson, M., Rice, K., & Maier, S. (2009). The "Toll" of Opiod-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia. Trends in Pharmacological Sciences, 30(11), 581-591. DOI Scopus326 WoS287 Europe PMC252
2009	Rodgers, K., Hutchinson, M., Northcutt, A., Maier, S., Watkins, L., & Barth, D. (2009). The cortical innate immune response increases local neuronal excitability leading to seizures. Brain, 132(9), 2478-2486. DOI Scopus132 WoS120 Europe PMC103
2009	Bland, S., Hutchinson, M., Maier, S., Watkins, L., & Johnson, K. (2009). The glial activation inhibitor AV411 reduces morphine-induced nucleus accumbens dopamine release. Brain Behavior and Immunity, 23(4), 492-497. DOI Scopus84 WoS66 Europe PMC74
2009	Hutchinson, M., Lewis, S., Coats, B., Skyba, D., Crysdale, N., Berkelhammer, D., . . . Johnson, K. (2009). Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast). Brain Behavior and Immunity, 23(2), 240-250. DOI Scopus215 WoS196 Europe PMC182
2008	Hutchinson, M., Coats, B., Lewis, S., Zhang, Y., Sprunger, D., Rezvani, N., . . . Watkins, L. (2008). Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behavior and Immunity, 22(8), 1178-1189. DOI Scopus267 WoS227 Europe PMC209
2008	Hutchinson, M., Northcutt, A., Chao, L., Kearney, J., Zhang, Y., Berkelhammer, D., . . . Maier, S. (2008). Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia. Brain Behavior and Immunity, 22(8), 1248-1256. DOI Scopus163 WoS139 Europe PMC124
2008	Hutchinson, M., Zhang, Y., Brown, K., Coats, B., Shridhar, M., Sholar, P., . . . Watkins, L. (2008). Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). European Journal of Neuroscience, 28(1), 20-29. DOI Scopus338 WoS308 Europe PMC286
2007	Watkins, L., Hutchinson, M., Milligan, E., & Maier, S. (2007). 'Listening' and 'talking' to neurons: Implications of immune activation for pain control and increasing the efficacy of opioids. Brain Research Reviews, 56(1), 148-169. DOI Scopus159 WoS135 Europe PMC121
2007	Der-Avakian, A., Bland, S., Rozeske, R., Tamblyn, J., Hutchinson, M., Watkins, L., & Maier, S. (2007). The effects of a single exposure to uncontrollable stress on the subsequent conditioned place preference responses to oxycodone, cocaine, and ethanol in rats. Psychopharmacology, 191(4), 909-917. DOI Scopus37 WoS33 Europe PMC28
2007	Watkins, L., Hutchinson, M., Ledeboer, A., Wieseler-Frank, J., Milligan, E., & Maier, S. (2007). Glia as the "bad guys": Implications for improving clinical pain control and the clinical utility of opioids. Brain Behavior and Immunity, 21(2), 131-146. DOI Scopus307 WoS260 Europe PMC224
2007	Hutchinson, M., Johnson, K., Rice, K., Maier, S., & Watkins, L. (2007). Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward. The Scientific World Journal, 7(Suppl 2), 98-111. DOI Scopus317 WoS14 Europe PMC233
2007	Ledeboer, A., Hutchinson, M., Watkins, L., & Johnson, K. (2007). Ibudilast (AV-411): A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opinion on Investigational Drugs, 16(7), 935-950. DOI Scopus134 WoS115 Europe PMC99
2005	Hutchinson, M., & Somogyi, A. (2005). Characterisation of the in vitro modulation of splenocyte proliferation by non-4,5-epoxymorphinan opioids. International Immunopharmacology, 5(12), 1713-1722. DOI Scopus6 WoS4 Europe PMC4
2005	Watkins, L., Hutchinson, M., Johnston, I., & Maier, S. (2005). Glia: novel counter-regulators of opioid analgesia. Trends in Neurosciences, 28(12), 661-669. DOI Scopus299 WoS259 Europe PMC218
2004	Hutchinson, M., & Somogyi, A. (2004). (S)-(+)methadone is more immunosuppressive than the potent analgesic (R)-(-)-methadone. International Immunopharmacology, 4(12), 1525-1530. DOI Scopus13 WoS12 Europe PMC11
2004	Hutchinson, M., La Vincente, S., & Somogyi, A. (2004). In vitro opioid induced proliferation of peripheral blood immune cells correlates with in vivo cold pressor pain tolerance in humans: a biological marker of pain tolerance. Pain, 110(3), 751-755. DOI Scopus13 WoS11 Europe PMC10
2004	Hutchinson, M., & Somogyi, A. (2004). Relationship between 4,5-epoxymorphinan structure and in vitro modulation of cell proliferation. European Journal of Pharmacology, 494(2-3), 251-262. DOI Scopus10 WoS7 Europe PMC8
2004	Hutchinson, M., Menelaou, A., Foster, D., Coller, J., & Somogyi, A. (2004). CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes. British Journal of Clinical Pharmacology, 57(3), 287-297. DOI Scopus133 WoS96 Europe PMC73
2003	Menelaou, A., Hutchinson, M., Quinn, I., Christensen, A., & Somogyi, A. (2003). Quantification of the O- and N-demethylated metabolites of hydrocodone and oxycodone in human liver microsomes using liquid chromatography with ultraviolet absorbance detection. Journal of Chromatography. B, Analytical Techniques in the Biomedical and Life Sciences, 785(1), 81-88. DOI Scopus23 WoS19 Europe PMC12
2002	Hutchinson, M., & Somogyi, A. (2002). Diacetylmorphine degradation to 6-monoacetylmorphine and morphine in cell culture: implications for in vitro studies. European Journal of Pharmacology, 453(1), 27-32. DOI Scopus18 WoS18 Europe PMC13
-	Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Toll-like receptor-4 antagonist (+)-naloxone elicits sexually dimorphic attenuation of inflammation-induced fetal programming in mice. Supplemental Tables 1-5. DOI

Book Chapters

Year	Citation
2022	Mustafa, S., Evans, S., Barry, B., Barratt, D., Wang, Y., Lin, C., . . . Hutchinson, M. R. (2022). Toll-Like Receptor 4 in Pain: Bridging Molecules-to-Cells-to-Systems.. In V. Kumar (Ed.), Toll-like Receptors in Health and Disease. Handbook of Experimental Pharmacology (Vol. 276, pp. 239-273). Springer Berlin Heidelberg. DOI Scopus2 Europe PMC2
2018	Holmes, J., Corrigan, F., & Hutchinson, M. R. (2018). Neuroimmunopharmacology at the Interface of Inflammation and Pharmacology Relevant to Depression. In B. T. Baune (Ed.), Inflammation and Immunity in Depression Basic Science and Clinical Applications (pp. 223-240). United Kingdom: Academic Press. DOI
2015	Thomas, J., Sanam, M., Johnson, J., & Nicotra, L. (2015). The relationship between opioids and immune signalling in the spinal cord. In Handbook of Experimental Pharmacology (Vol. 227, pp. 207-238). Springer Berlin Heidelberg. DOI Scopus20 Europe PMC13
2014	Wang, X., Cochran, T. A., Hutchinson, M. R., Yin, H., & Watkins, L. R. (2014). Drug addiction. In M. E. Tremblay, & A. Sierra (Eds.), Microglia in health and disease (pp. 299-317). Online: Springer New York. DOI Scopus6
2013	Sumracki, N., Nicotra, L., Kwok, Y., Liu, L., Steeg, K., Watkins, L., & Hutchinson, M. (2013). The future: new concepts and potential therapies. In C. Toth, & D. Moulin (Eds.), Neuropathic pain: causes, management and understanding (1 ed., pp. 341-356). United Kingdom: Cambridge University Press. DOI
2013	Wu, Y., & Hutchinson, M. (2013). Therapeutic strategies to treat alcohol-related disorders targeting central immune signaling. In C. Cui, L. Grandison, & A. Noronha (Eds.), Neural-Immune Interactions in Brain Function and Alcohol Related Disorders (1 ed., pp. 535-559). United States: Springer. DOI
2013	Kusnecov, A. W., & Anisman, H. (Eds.) (2013). The Wiley‐Blackwell Handbook of Psychoneuroimmunology. In . Wiley. DOI
2013	Kusnecov, A. W., & Anisman, H. (Eds.) (2013). The Wiley‐Blackwell Handbook of Psychoneuroimmunology. In . Wiley. DOI
2013	Grace, P. M., Watkins, L. R., & Hutchinson, M. R. (2013). Immune-to-Brain Communication in Pain: Historical Perspectives, New Directions. In The Wiley-Blackwell Handbook of Psychoneuroimmunology (pp. 176-197). Wiley. DOI
2012	Grace, P., Watkins, L., & Hutchinson, M. (2012). The Role of the Immune System in Chronic Pain Comorbidities. In M. Giamberardino, & T. Jensen (Eds.), Pain Comorbidities: Understanding and Treating the Complex Patient (1 ed., pp. 137-155). Seattle, WA: USA: IASP Press (International Association for the Study of Pain).
2009	Gordon, A., Hutchinson, M., La Vincente, S., Mitchell, T., Morrish, G., Newcombe, D., . . . White, J. (2009). Pharmacology of opioid agonists and antagonists. In R. Mattick, R. Ali, & N. Lintzeris (Eds.), Pharmacotherapies for the Treatment of Opioid Dependence: Efficacy, Cost-Effectiveness and Implementation Guidelines (pp. 15-53). New York, USA: Informa.
2007	Watkins, L. R., Wieseler-Frank, J., Hutchinson, M. R., Ledeboer, A., Spataro, L., Milligan, E. D., . . . Maier, S. F. (2007). Neuroimmune interactions and pain: The role of immune and glial cells. In Psychoneuroimmunology, Two-Volume Set (Vol. 1, pp. 393-414). Elsevier. DOI Scopus6
2006	Watkins, L. R., Wieseler-Frank, J., Hutchinson, M. R., Ledeboer, A., Spataro, L., Milligan, E. D., . . . Maier, S. F. (2006). Neuroimmune Interactions and Pain: The Role of Immune and Glial Cells. In Psychoneuroimmunology (pp. 393-414). DOI Scopus2

Conference Papers

Year	Citation
2023	Smith, D. L., Nguyen, L. V., Reja, M. I., Ottaway, D. J., & Warren-Smith, S. C. (2023). Exploiting Complex Light Propagation in Multimode Fibers for Multi-Point Sensing. In Proceedings - 28th International Conference on Optical Fiber Sensors, OFS 2023 (pp. Tu3.53). Online: Optical Society of America. DOI
2020	Yao, H., Jiang, J., Xin, J., Shi, D., Mohamed, H. M. H., He, L., . . . Li, J. (2020). RNA AND SMALL RNA PROFILING OF PERIPHERAL BLOOD MONONUCLEAR CELLS REVEALS REGULATORY NETWORKS IN EMT-INDUCED FIBROGENESIS DURING THE PROGRESSION OF HEPATITIS B VIRUS-RELATED LIVER CIRRHOSIS. In HEPATOLOGY Vol. 72 (pp. 518A). ELECTR NETWORK: WILEY.
2019	Schartner, E., Musolino, S., Salem, A., Hutchinson, M., & Monro, T. (2019). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015 (pp. 1). online: OSA Publishing.
2019	Schartner, E., Tsiminis, G., Henderson, M., Hutchinson, M., & Monro, T. (2019). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015. online: OSA Publishing.
2019	Kostecki, R., Zhang, B., El Habti, A., Arman, A., Hutchinson, M., Tricker, P., . . . Ebendorff-Heidepriem, H. (2019). Reversible protein carbonylation in-vivo biosensor. In osapublishing.org Vol. Part F166-Sensors 2019 (pp. 1-2). online: OSA. DOI
2019	Peng, L., Khalid, A., Warren-Smith, S. C., Arman, A., Schartner, E. P., Sylvia, G. M., . . . Li, J. (2019). Chemical sensing based on silk coated exposed-core fibers. In E. M. Goldys, & B. C. Gibson (Eds.), Biophotonics Australasia 2019 Vol. 11202 (pp. 112020G-1-112020G-2). Bellingham, Washington: SPIE. DOI
2019	Kostecki, R., Zhang, B., El Habti, A., Arman, A., Hutchinson, M. R., Tricker, P. J., . . . Ebendorff-Heidepriem, H. (2019). Optical fiber based in-vivo oxidative stress biosensor. In Proceedings of SPIE - The International Society for Optical Engineering Vol. 11202 (pp. 1-3). online: SPIE. DOI WoS1
2017	Hutchinson, M. R. (2017). The importance of knowing you are sick: Biophotonics for the 'Other' brain. In Optics InfoBase Conference Papers Vol. Part F41-CLEO_SI 2017 (pp. 1 page). San Jose, CA: IEEE. DOI WoS1
2017	Liu, G., Zhang, K., Nadort, A., Hutchinson, M., & Goldys, E. (2017). An optical fibre based ex-vivo device for detection of cytokines. In IET Conference Publications Vol. 2017 (pp. 1-4). online: IET Digital Library. DOI
2017	Tsiminis, G., Schartner, E., Brooks, J., & Hutchinson, M. (2017). Measurements of vitamin B12 in human blood serum using resonance Raman spectroscopy. In Proceedings of the 29th IEEE Photonics Conference (pp. 684-685). Waikoloa, HI: IEEE. DOI Scopus1 WoS2
2016	Tsiminis, G., Schartner, E., Bekteshi, M., Hutchinson, M., & Ebendorff-Heidepriem, H. (2016). Hollow-core optical fibers made by glass billet extrusion as sensors for raman spectroscopy. In Optics InfoBase Conference Papers Vol. Part F3-ACOFT 2016 (pp. 1-2). online: OSA. DOI
2016	Musolino, S., Schartner, E., Tsiminis, G., Salem, A., Monro, T., & Hutchinson, M. (2016). A portable optical fiber probe for in vivo brain temperature measurements. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 4 pages). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING. DOI Scopus3 WoS1
2016	Staikopoulos, V., Gosnell, M., Anwer, A., Mustafa, S., Hutchinson, M., & Goldys, E. (2016). Hyperspectral imaging of endogenous fluorescent metabolic molecules to identify pain states in central nervous system tissue. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 1-8). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING. DOI Scopus3 WoS3
2016	Peddie, V., Heng, S., Mustafa, S., Thomas, J., Hutchinson, M., & Abell, A. (2016). Shapeshifting photoswitchable azobenzene compounds and their biological applications. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 4 pages). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING. DOI
2016	Tsiminis, G., Schartner, E., Brooks, J., & Hutchinson, M. (2016). Measurements of vitamin B12 in human blood serum using resonance Raman spectroscopy. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE: SPIE BioPhotonics Australasia Conference Vol. 10013 (pp. 100130M-1-100130M-4). Adelaide, Australia: SPIE. DOI
2016	Tsiminis, G., Schartner, E., Hutchinson, M., & Ebendorff-Heidepriem, H. (2016). Hollow core optical fibres made by glass billet extrusion as sensors for Raman spectroscopy. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 4 pages). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING. DOI
2016	Bajic, J., Whittaker, A., Bobrovskaya, L., Hutchinson, M., & Howarth, G. (2016). Intestinal mucositis induced by 5-Fluorouracil results in glial changes modified by analgesics via neuro-immune mechanisms. In Australian Society for Medical Research. Adelaide.
2016	Whittaker, A. L., Bajic, J. E., Bobrovskaya, L., Hutchinson, M. R., & Howarth, G. S. (2016). Chemotherapy Induces Intestinal Inflammation and Central Changes Which Are Modified by Analgesics via Neuro-Immune Mechanisms. In GASTROENTEROLOGY Vol. 150 (pp. S52). San Diego, CA: W B SAUNDERS CO-ELSEVIER INC. DOI
2015	Dodds, K., Beckett, E., Staikopoulos, V., Evans, S., & Hutchinson, M. (2015). Novel mouse model of endometriosis permits identification of spinal glia and nociception characteristics involved in pelvic pain. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 267). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2015	Staikopoulos, V., Jin, D., Lu, Y., Gibson, B., Reineck, P., Goldys, E., . . . Hutchinson, M. (2015). Ultra-structural imaging in cleared mouse cns using nanoparticles. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 382). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2015	Jacobsen, J., Staikopoulos, V., & Hutchinson, M. (2015). Optimisation and utilisation of a novel whole-brain imaging technique (clarity) to analyse addiction-like behaviours. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 351). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2015	Schartner, E., Musolino, S., Salem, A., Hutchinson, M., & Monro, T. (2015). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Optics InfoBase Conference Papers.
2015	Schartner, E. P., Musolino, S., Salem, A., Hutchinson, M. R., & Monro, T. M. (2015). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Optics InfoBase Conference Papers.
2015	Schartner, E. P., Musolino, S., Salem, A., Hutchinson, M. R., & Monro, T. M. (2015). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015.
2015	Schartner, E. P., Tsiminis, G., Henderson, M. R., Hutchinson, M. R., & Monro, T. M. (2015). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. In Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015.
2015	Schartner, E. P., Tsiminis, G., Henderson, M. R., Hutchinson, M. R., & Monro, T. M. (2015). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. In Optics InfoBase Conference Papers.
2014	Maeda, H. (2014). THE EPR EFFECT AND BEYOND FOR CANCER SELECTIVE DRUG DELIVERY FOR TREATMENT AND IMAGING USING NANOMEDICINE. In DRUG METABOLISM REVIEWS Vol. 45 (pp. 15). Toronto, CANADA: INFORMA HEALTHCARE.
2014	Narayan, D., Casson, R. J., Ebneter, A., Chidlow, G., Grace, P. M., Hutchinson, M. R., & Wood, J. P. M. (2014). Immune priming and experimental glaucoma: The effect of prior systemic lipopolysaccharide challenge on tissue outcomes after optic nerve injury. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55 (pp. 7 pages). ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
2007	Hutchinson, M. R., Coats, B. D., Zhang, Y., Lewis, S. S., Sprunger, D. B., Baker, E. M., . . . Watkins, L. R. (2007). Opioid-induced glial activation via a non-classical opioid receptor: clinical implications & the search for the target. In NEURON GLIA BIOLOGY Vol. 2 (pp. S16). CAMBRIDGE UNIV PRESS. WoS1
1995	Linch, D. C., Milligan, D. W., Winfield, D. A., Kelsey, S., Johnson, S., Littlewood, T., . . . Long, S. G. (1995). G-CSF significantly accelerates neutrophil recovery after peripheral blood stem cell transplantation (PBSCT) in lymphoma patients and shortens the time in hospital; Preliminary results of a randomised BNLI trial.. In BLOOD Vol. 86 (pp. 873). AMER SOC HEMATOLOGY.

Conference Items

Year	Citation
2023	Hutchinson, M., Barratt, D. T., Holmes, J., Mustafa, S., Bajic, J. E., Kolarich, D., . . . Semmler, C. (2023). From blood markers to performance prediction: New insights for athletes and beyond. Poster session presented at the meeting of BRAIN BEHAVIOR AND IMMUNITY. CO, Boulder: ACADEMIC PRESS INC ELSEVIER SCIENCE. DOI
2023	Mustafa, S., Evans, S., & Hutchinson, M. (2023). Breaking ground in pain research: Advancements in TLR4 signaling pathways and implications for brain-behavior-immunity crosstalk. Poster session presented at the meeting of Abstracts of the PsychoNeuroImmunology Research Society Annual Meeting (PNIRS 2023), as published in Brain, Behavior, and Immunity. Boulder, CO, USA: Elsevier. DOI
2020	Ho, R. M., Yin, C. P., Robertson, S. A., Hutchinson, M. L., & Keelan, J. A. (2020). Comparative Effects of TLR4 Inhibitors on Inflammatory Activation in Human Decidual Cells.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG.
2016	Bajic, J. E., Whittaker, A. L., Bobrovskaya, L., Hutchinson, M. R., & Howarth, G. S. (2016). Intestinal mucositis induced by 5-Fluorouracil results in glial changes modified by analgesics via neuro-immune mechanisms. Poster session presented at the meeting of Multinational Association for Supportive Care in Cancer. Adelaide.
2015	Bajic, J., Howarth, G., Eden, G., Lampton, L., Mashtoub, S., & Hutchinson, M. (2015). Intestinal mucositis induced by 5-fluorouracil results in spinal astrocyte expression changes in rats. Poster session presented at the meeting of Journal of Neurochemistry. Cairns, Australia: Wiley. DOI WoS1
2014	Bajic, J. E., Howarth, G. S., Eden, G. L., Lampton, L. S., Mashtoub, S., & Hutchinson, M. R. (2014). Intestinal mucositis induced by 5-fluorouracil results in spinal astrocyte expression changes in rats. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Broadbeach, Qld.: Wiley. DOI
2014	Schartner, E., Musolino, S., Salem, A., Hutchinson, M., & Monro, T. (2014). Rare-earth thermometry using functionalised optical fibre tips for in vivo measurements of brain temperature. Poster session presented at the meeting of Optics InfoBase Conference Papers.
2014	Schartner, E., Tsiminis, G., Henderson, M., Hutchinson, M., & Monro, T. (2014). A comparison between multimode tip and suspended core fluorescence optical fibre sensors. Poster session presented at the meeting of Optics InfoBase Conference Papers.
2014	Li, Y., Coller, J., Hutchinson, M., Klein, K., Zanger, U., Currow, D., . . . Somogyi, A. (2014). Cyp2B6*6 Allele Alters Ketamine'S Pharmacokinetics In Chronic Pain Patients And Metabolism In Vitro. Poster session presented at the meeting of Drug Metabolism Reviews. Toronto, CANADA: Informa Healthcare. DOI Europe PMC3
2014	Robertson, S. A., Chin, P. -Y., Dorian, C., & Hutchinson, M. (2014). Inhibition of the TLR4 Signalling Pathway Protects Mice from LPS-Induced Preterm Delivery. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC.
2014	Robertson, S. A., Wahid, H. W., Dorian, C., Hutchinson, M., & Olson, D. M. (2014). Toll-Like Receptor 4 (TLR4) Signalling Is Implicated in Normal On-Time Labour in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC.
2013	Rolan, P. E., Hutchinson, M. R., Buijs, M., Tuke, J., Kwok, Y. H., Gentgall, M., . . . Nillsen, N. (2013). First demonstration of the neuroimmune link in humans using IV Endotoxin and Intradermal Capsaicin in the face and arm. Poster session presented at the meeting of JOURNAL OF HEADACHE AND PAIN. SPRINGER-VERLAG ITALIA SRL. DOI
2013	Kwiatek, R., Hutchinson, M., Cleland, L., Limaye, V., True, B., Lubhan, C., . . . Coller, J. (2013). GENETIC VARIABILITY IN CYTOKINE AND CYTOKINE RECEPTORS IN FIBROMYALGIA - A PILOT STUDY. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY-BLACKWELL.
2013	Hutchinson, M. R. (2013). THE PROINFLAMMATORY HYPOTHESIS OF ADDICTION: CLINICAL AND PRECLINICAL EVIDENCE.. Poster session presented at the meeting of JOURNAL OF NEUROIMMUNE PHARMACOLOGY. SPRINGER.
2013	Johnson, J., Hutchinson, M., Williams, D., & Rolan, P. (2013). Codeine, Increasing Pain & Medication Overuse Headache: The First Evidence of Codeine-Induced Hyperalgesia. Poster session presented at the meeting of CEPHALALGIA. Boston, MA: SAGE PUBLICATIONS LTD.
2012	Zwicker, J. D., Zhang, Y., Hutchinson, M. R., Rice, K. C., Watkins, L. R., & Funk, G. D. (2012). Microglia attenuate the opioid-induced depression of preBotzinger Complex (preBotC) inspiratory rhythm in vitro via a TLR4-independent pathway. Poster session presented at the meeting of FASEB JOURNAL. San Diego, CA: FEDERATION AMER SOC EXP BIOL. WoS1
2012	Narayan, D., Wood, J., Ebneter, A., Chidlow, G., Grace, P., Hutchinson, M., & Casson, R. (2012). IMMUNE PRIMING AND EXPERIMENTAL GLAUCOMA: THE EFFECT OF PRIOR SYSTEMIC LIPOPOLYSACCHARIDE CHALLENGE ON TISSUE OUTCOMES AFTER OPTIC NERVE INJURY. Poster session presented at the meeting of CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. WILEY-BLACKWELL.

Internet Publications

Year	Citation
-	Morphett, J., Whittaker, A., Reichelt, A., & Hutchinson, M. (n.d.). Perineuronal net structure as a non-cellular mechanism of affective state, a scoping review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols. DOI

Datasets

Year	Citation
-	Liddicoat, C., Sydnor, H., Cando-Dumancela, C., Dresken, R., Liu, J., Gellie, N., . . . Breed, M. (n.d.). Supporting Data - Naturally-diverse airborne environmental microbial exposures modulate the gut microbiome and may provide anxiolytic benefits in mice. DOI

Figures

Year	Citation
-	Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Toll-like receptor-4 antagonist (+)-naloxone elicits sexually dimorphic attenuation of inflammation-induced fetal programming in mice. Supplemental Figure 1. DOI

Preprint

Year	Citation
2025	Madden, V., Mqadi, L., Arendse, G., Bedwell, G., Msolo, N., Lesosky, M., . . . Joska, J. (2025). Provoked cytokine response is not associated with distress or induced secondary hyperalgesia in people with suppressed HIV. DOI
2025	Mqadi, L., Bedwell, G., Msolo, N., Arendse, G., Lesosky, M., Kamerman, P., . . . Madden, V. (2025). Distress is positively associated with induced secondary hyperalgesia in people with suppressed HIV. DOI
2024	Bedwell, G., Mqadi, L., Kamerman, P., Hutchinson, M., Parker, R., & Madden, V. (2024). Inflammatory reactivity is unrelated to childhood adversity or provoked modulation of nociception. DOI

My research program has been funded by the following grant schemes

Centre for Advanced Defence Research and Enterprise - OCE (CIB)
SA Sheep Industry Fund - Pain Mitigation (CIA)
DSTG, Centre for Advanced Defence Research and Enterprise – OCE
DSTG, Defence Science Technology Group - SynBioGen programs
DSTG, Human Integrated Sensor System Program - Meat and Livestock Australia
ARC Future Fellowship (FT180100565; Sole CI)
ARC discovery grant that includes an ARF (DP110100297; Sole CI)
NHMRC CJ Martin Postdoctoral Fellowship (Sole CI)
NHMRC project grant (APP1026178; CIB).
ARC Centre of Excellence for Nanoscale BioPhotonics ($38M, CE140100003)
NIH R01 grants as a PI (R01 DA034185; R01 DA025978; R01 DA23132; R01 DE017782)
USA Department of Defence CDMRP grant ($614K)
National Breast Cancer Foundation of Australia ($112K)
USA Fibromyalgia Association pilot grant ($55K)
~$3M contract research on neuroimmune targeted therapies for pharmaceutical companies such as Phebra, Bionomics, Avigen, Covidien, Implicit Biosciences, NovImmune, Merck and J&J.

I regularly teach into continuing medical education courses for Medical Colleges, Faculties and Societies.

I also teach into several University of Adelaide undergraduate courses as an invited specialist lecturer

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2025	Co-Supervisor	Using Virtual Reality to induce positive affect and explore the impact on wellbeing and anhedonia.	Doctor of Philosophy	Doctorate	Full Time	Mr Elliot Howard
2025	Principal Supervisor	Investigating the role of TLR4 antagonists and the effects on chronic pain: a structural biology journey	Doctor of Philosophy under a Jointly-awarded Degree Agreement with	Doctorate	Full Time	Mr Anston Savio D'silva
2024	Co-Supervisor	Strength training interventions for people at risk of osteopenia or osteoporosis	Doctor of Philosophy	Doctorate	Full Time	Ms Riccarda Albana Quattlaender
2024	Co-Supervisor	A phenotypic and genetic approach to identify fossil frogs from Naracoorte caves with comparison to modern Australian species in the southeast.	Doctor of Philosophy	Doctorate	Full Time	Miss Natasha Lee Hiotis
2022	Co-Supervisor	Oxidative stress activated prodrugs	Master of Philosophy	Master	Full Time	Mr Ravindu Ranasinghe
2022	Principal Supervisor	The Human Integrated Sensor System (HISS) Challenge	Doctor of Philosophy	Doctorate	Full Time	Mr Michail Laoumtzis
2021	Principal Supervisor	Exploring the neurobiological bases of affective states	Doctor of Philosophy	Doctorate	Part Time	Jane Cerina Morphett
2021	Principal Supervisor	Regulation of the neuro-immune system	Doctor of Philosophy	Doctorate	Part Time	Mr Benjamin Daniel Barry
2021	Co-Supervisor	Effectiveness of Exercise to Improve Patient-Reported and Central Pain Modulation Outcomes in Chronic Neck Pain	Doctor of Philosophy	Doctorate	Full Time	Mr Kexun Kenneth Chen
2021	Principal Supervisor	Quantification of the lifetime experience of pain in livestock and its implications on productivity and animal husbandry practices, including applications to human health and wellbeing	Doctor of Philosophy	Doctorate	Part Time	Miss Charlotte Helen Johnston
2021	Co-Supervisor	The physiological impacts of virtual fencing on sheep and cattle in South Australia.	Doctor of Philosophy	Doctorate	Part Time	Miss Megan Beth Willis
2020	Principal Supervisor	Immunophenotyping of Spinal Cord Injured Patients – Advancing Diagnostics and Prognostics.	Doctor of Philosophy	Doctorate	Part Time	Mr James Edward Swift

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2019 - 2019	Principal Supervisor	Peripheral-to-Central Neuroimmune Communication and the Sun: Implications for Addiction and Neurodegenerative Disease Pathology	Master of Philosophy (Medical Science)	Master	Full Time	Ms Krystal Lee Iacopetta
2019 - 2024	Principal Supervisor	Investigating the effect of mesenchymal stem cells and conditioned media for the treatment of pain and neuropathic pain	Doctor of Philosophy	Doctorate	Full Time	Mr Chrysostomos Constantine Maoudis
2018 - 2022	Co-Supervisor	Assessing Pain and Treatment Responsiveness in a Patient Cohort and Mouse Model of Inflammatory Arthritis Using Neurobiophotonics	Doctor of Philosophy	Doctorate	Full Time	Miss Florence Lees
2016 - 2020	Principal Supervisor	The Role of Nitroxyl in the Development of Neuropathic Pain	Doctor of Philosophy	Doctorate	Full Time	Mrs Vicky Staikopoulos
2015 - 2020	Principal Supervisor	Investigation of a Functional Relationship Between Toll-Like Receptor 4 and Transient Receptor Potential Cation Channel Subfamily V Member 1 in Relation to a Novel Neuroimmune Pain Model	Doctor of Philosophy	Doctorate	Full Time	Mr Samuel Greig Evans
2015 - 2020	Principal Supervisor	Advanced Preclinical Assessment of Hyper-Nociception	Doctor of Philosophy	Doctorate	Full Time	Mr Azim Arman
2014 - 2017	Principal Supervisor	Exploring the Bidirectional Interface between Stress and Innate Immunity: A Focus on Glucocorticoid and TLR4-MyD88 Signalling	Doctor of Philosophy	Doctorate	Full Time	Dr Jiajun Liu
2014 - 2018	Co-Supervisor	Investigating the role of Toll-like receptor 4 in myocardial ischaemic-preconditioning and ischaemic-reperfusion injury	Doctor of Philosophy	Doctorate	Full Time	Sam Man Lee
2014 - 2018	Principal Supervisor	Exploring the Role of Spinal Glia and Toll-Like Receptor 4 in the Development of Endometriosis and Neuroimmune-Associated Pain	Doctor of Philosophy	Doctorate	Full Time	Kelsi Nicole Dodds
2014 - 2019	Co-Supervisor	An optical fibre point temperature sensor for investigation of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') induced hyperthermia in the rat brain	Doctor of Philosophy	Doctorate	Full Time	Mr Stefan Tyrone Musolino
2014 - 2019	Principal Supervisor	From the Bottom Up: Chemotherapy-Induced Gut Toxicity, Glial Reactivity and Cognitive Impairment	Doctor of Philosophy	Doctorate	Part Time	Dr Juliana Esma Bajic
2014 - 2022	Principal Supervisor	Experimental Models of Alcohol Induced Inflammation-associated Depressive-like Behaviour	Doctor of Philosophy	Doctorate	Part Time	Joshua Luke Holmes
2013 - 2017	Co-Supervisor	Toll-Like Receptor 4 Signalling in Inflammation Pathways to Term and Preterm Delivery	Doctor of Philosophy	Doctorate	Full Time	Miss Hanan Hamimi Binti Wahid
2013 - 2017	Principal Supervisor	Exploring the Pharmacology of (+)-Naltrexone on Alcohol Reward and Anxiety Behaviours	Doctor of Philosophy	Doctorate	Full Time	Jonathan Henry Jacobsen
2011 - 2017	Principal Supervisor	Neuroimmunopharmacology of Opioids	Doctor of Philosophy	Doctorate	Full Time	Dr Jacob Henry Lloyd Thomas
2010 - 2015	Co-Supervisor	The thermal grill as a tool to investigate analgesic clinical pharmacology	Doctor of Philosophy	Doctorate	Full Time	Mrs Nicole Martha Sumracki
2010 - 2014	Co-Supervisor	Pharmacogenetics of Ketamine Metabolism and Immunopharmacology of Ketamine	Doctor of Philosophy	Doctorate	Full Time	Mr Yibai Li
2010 - 2015	Principal Supervisor	Sex Differences in Allodynia: A complex Interaction Between 17beta-Oestradiol and the Innate Immune System	Doctor of Philosophy	Doctorate	Full Time	Miss Lauren Louise Nicotra
2010 - 2015	Co-Supervisor	Codeine, heightened pain sensitivity and medication overuse headache: A neuroimmune hypothesis and novel treatment strategy.	Doctor of Philosophy	Doctorate	Full Time	Miss Jacinta Lee Johnson
2009 - 2014	Co-Supervisor	Potential peripheral biomarkers for chronic pain	Doctor of Philosophy	Doctorate	Full Time	Miss Yuen Kwok
2009 - 2011	Co-Supervisor	CNS Immune Signalling and Drug Addiction: Role of Interleukin-1 Beta	Doctor of Philosophy	Doctorate	Full Time	Mr Liang Liu
2008 - 2011	Co-Supervisor	The Neuroimmunopharmacology of Alcohol	Doctor of Philosophy	Doctorate	Full Time	Miss Yue Wu
2007 - 2011	Co-Supervisor	Two methods of biomarker discovery: applications in neuropathic pain and pharmacotherapy	Doctor of Philosophy	Doctorate	Full Time	Mr Peter Grace

Board Memberships

Date	Role	Board name	Institution name	Country
2024 - ongoing	Member	National Science and Technology Council	National Science and Technology Council	Australia
2024 - ongoing	Member	Australian Economic Accelerator Board	Australian Economic Accelerator Board	Australia
2024 - ongoing	Board Member	the Prime Minister’s National Science and Technology Council	the Prime Minister’s National Science and Technology Council	Australia
2022 - 2023	Board Member	Ministerial Review of the 2001 ARC Act Legislation	Ministerial Review of the 2001 ARC Act Legislation	Australia
2022 - 2023	Member	Ministerial Review of the 2001 ARC Act Legislation	Ministerial Review of the 2001 ARC Act Legislation	Australia
2022 - ongoing	Member	the DSTG CBRN STaR Shot OSAC advisory council	DSTG CBRN STaR Shot OSAC	Australia
2022 - ongoing	Member	Ministerial Review of the 2001 ARC Act Legislation	ARC	Australia
2020 - ongoing	Founder	The Animal Welfare Collaborative	The Animal Welfare Collaborative	Australia
2013 - 2024	Chair	Centre for Nanoscale BioPhotonics	Centre for Nanoscale BioPhotonics	Australia
2013 - ongoing	Board Member	Science Technology Australia	-	Australia

Committee Memberships

Date	Role	Committee	Institution	Country
2023 - ongoing	Chair	STEM Career Pathways Review for the Office of the Chief Scientist	STEM Career Pathways Review for the Office of the Chief Scientist	Australia
2022 - ongoing	Chair	the Australian Pain Solutions Research Alliance steering committee	the Australian Pain Solutions Research Alliance steering committee	Australia
2022 - ongoing	Chair	the Safeguarding Australia through Biotechnology Response and Engagement (SABRE) Alliance steering committee	SABRE Alliance Steering Committee	Australia
2020 - ongoing	Chair	Davies Livestock Research Centre advisory committee	Davies Livestock Research Centre advisory committee	Australia
2013 - 2024	Convener	Centre for Nanoscale BioPhotonics	Centre for Nanoscale BioPhotonics	Australia

Memberships

Date	Role	Membership	Country
2012 - ongoing	Member	Australian Pain Society	Australia
2007 - ongoing	Member	International Association for the Study of Pain	United States
2007 - ongoing	Member	Psychoneuroimmunology Research Society	United States
2002 - ongoing	Member	Society for Neuroscience	United States
1999 - ongoing	Representative	Australasian Society for Clinical and Experimental Pharmacology and Toxicology	Australia

Consulting/Advisories

Date	Institution	Department	Organisation Type	Country
2022 - ongoing	The Australian Research Council, CEO Advisory Council	The Australian Research Council	Scientific research	Australia
2022 - ongoing	DSTG, Human Integrated Sensory System Program	DSTG	Scientific research	Australia

Editorial Boards

Date Role Editorial Board Name Institution Country

2015 - ongoing Associate Editor Brain, Behavior, and Immunity - -

Date	Role	Editorial Board Name	Institution	Country
2015 - ongoing	Associate Editor	Brain, Behavior, and Immunity	-	-

Position: Interim Director, IPAS
Phone: 83130322
Email: mark.hutchinson@adelaide.edu.au
Fax: 82240685
Campus: North Terrace
Building: Helen Mayo South, floor Fifth Floor
Org Unit: Institute for Photonics and Advanced Sensing