Associate Professor Louise Hull
Associate Professor
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Associate Professor Louise Hull has worked in fertility services since she graduated as a doctor in 1991. During this time she has been delighted to help many couples conceive, as well as promote the development of improved fertility treatments through research and education. Associate Professor Louise Hull works at the Robinson Research Institute, University of Adelaide, Women’s and Children’s Hospital, Adelaide and in private practice at 266 Melbourne Street www.louise-hull.com and O&G, www.oandg.com.au/team/associate-professor-louise-hull.
Associate Professor Louise Hull became an Obstetrician and Gynaecologist (FRANZCOG) after gaining clinical experience working in IVF units in Christchurch, New Zealand, Cambridge, UK and Adelaide, Australia, including Bourn Hall, the fertility centre where the first IVF baby was born. She was awarded the Certificate in Reproductive Endocrinology and Infertility (CREI) sub speciality qualification by RANZCOG in 2006.
Associate Professor Hull completed a PhD s in Endometriosis at the University of Cambridge, UK in 2006. She was appointed to the University of Adelaide in 2006 where she established and led the Endometriosis Group at the Robinson Research Institute. Her research focuses on the basic science of endometriosis, developing new diagnostics for endometriosis and conducting Phase 3 and 4 pharmaceutical trials. She is an international ambassador for the World Endometriosis Society www.endometriosis.ca/about/ambassador/louise-hull, a Medical Advisory Board member for Endometriosis Australia and EndoNZ and participated in the National Action Plan round Table for Endometriosis by invitation from the Minister of Health. She has several national and international collaborations and has been awarded considerable grant money over the last 2 years to further endometriosis research in Australasia.
More recently Associate Professor Louise Hull has conducted research exploring the immunology and biology of implantation and has participated in biotechnology and pharmacology sponsored clinical trials in the IVF industry. She is the clinical leader of the Fertility and Conception Theme at the Robinson Institute, the co-chair of the Special Interest Group for Implantation of ASPIRE and has funding for several research projects exploring recurrent implantation failure and miscarriage.
Associate Professor Louise Hull publishes widely, presents at international conferences, supervises PhD students and teaches reproductive medicine to medical students, registrars and reproductive medicine fellows. She has received numerous grants, fellowships and awards. Additionally, Louise has been an associate editor for Human Reproduction, chaired several grant committees, sits on the Jean Hailes Governance Committee for the endometriosis national action plan and has been on the board of 3 IVF and software companies and 2 pharmaceutical medical advisory boards.
Associate Professor Louise Hull has founded 2 IVF units and in her roles as scientific director and new developments director has been integral in introducing novel treatments, laboratory methods and models of care to the IVF industry. She is currently the Written Exam Chair for the Certificate in Reproductive Endocrinology and Infertility (CREI) subspeciality for RANZCOG and the treasurer of the ANZCREI society.
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Appointments
Date Position Institution name 2019 Senior Consultant Associate Professor Louise Hull 2018 Governance Commitee Member Jean Hailes Foundation fro Women's Health NGO 2017 Consultant Fertility Specialist O & G 2017 Board Member Endocrinology Northwest 2015 Board Member Genea Oxford Fertility 2015 Board Member FAB Software Ltd 2015 Staff Specialist Gynaecologist Women's and Children's Hospital 2015 Assoc Prof Group Leader of the Endometriosis Research Group, Clinical Leader for the Fertility and Conception Theme The Robinson Research Institute, Research Centre for Reproductive Health , University of Adelaide 2011 - 2017 New Developments Director Fertility SA 2009 - 2018 Consultant Fertility Specialist Fertility SA 2009 - 2012 Board Member Fertility SA 2009 - 2010 Scientific Director Fertility SA 2009 Founding Member Fertility SA 2008 - 2014 Senior Lecturer University of Adelaide 2008 - 2009 Fertility Consultant Repromed 2008 Senior Lecturer University of Adelaide 2004 - 2008 Clinical Lecturer University of Adelaide 2004 - 2007 Subspecialist Trainee in Clinical Reproductive Endocrinology and Infertility (CREI) Repromed 2004 - 2007 Fertility Consultant Repromed 2000 - 2004 Research Associate and PhD candidate University of Cambridge 2000 - 2004 Specialist Registrar in Reproductive Medicine, Senior Specialist Registrar (NTN training position East Anglia Deanery) The Rosie Hospital 2000 - 2000 Locum Registrar Royal Free Hospital 1998 - 1999 Senior Registrar Tauton and Sommerset Hospital 1995 - 1998 Registrar Christchurch Women’s Hospital 1993 - 1995 Medical Officer of Special Scale Christchurch Women’s Hospital 1992 - 1992 Senior House Officer Nelson Hospital 1991 - 1992 House Officer Christchurch Public Hospital -
Awards and Achievements
Date Type Title Institution Name Country Amount 2016 Award Paper of the Month Robinson Research Institute Australia — 2015 Award Institute Paper of the Month Robinson Research Institute Australia — 2014 Teaching Award Professor Derek Frewin AO Citation for Clinical Teaching University of Adelaide Australia — 2014 Award Top 10% of reviewers Human Reproduction Update Australia — 2014 Award Top 10% of reviewers Human Reproduction Australia — 2014 Invitation Invited member of the Faculty of 1000 Faculty of 1000 Australia — 2013 Invitation Invited International Ambassador for the World Endometriosis Society World Endometriosis Society Australia — 2012 Award Professor Derek Frewin AO Citation for Clinical Teaching University of Adelaide Australia — 2009 Award Best original scientific paper Research Centre for Reproductive Medicine Australia — 2008 Award Best scientific paper, 10th World Congress of Endometriosis 10th World Congress of Endometriosis Australia — 2008 Award Best scientific paper 10th World Congress of Endometriosis Australia — 2004 Fellowship Burrough’s Welcome Travel Fellowship Society for Gynaecological Investigation United States — 1998 Award Runner up best presentation South West Obstetrics and Gynaecology Training Group United Kingdom — 1995 Award Immigrant Young Investigator Award NZ Medical Women’s Association Harvey Carey Memorial prize for best presentation New Zealand — 1989 Distinction Distinction in Obstetrics and Gynaecology University of Otago New Zealand — 1988 Distinction Basic Science and Clinical Science University of Otago New Zealand — -
Education
Date Institution name Country Title 2016 - 1991 Christchurch School of Medicine, University of Otago New Zealand MBChB 2003 - 2006 University of Cambridge United Kingdom PhD 1983 - 1986 University of Otago New Zealand BSc (Biochemistry and Microbiology) -
Postgraduate Training
Date Title Institution Country 2017 Certificate of Completion, Higher Education Academic Staff Leadership Colloquium Online National Excellence in Educational leadership Initiative (NEELI) Australia 2012 Graduate Australian Institute of Company Directors Australia 2012 Certificate of Reproductive Endocrinology and Infertility (CREI) RANZCOG Australia 2006 Fellowship RANZCOG Australia 1999 Diploma of Fertility and Family Planning (DFFP) Royal College of Obstetricians and Gynaecologists (RCOG) United Kingdom 1999 Member RANZCOG Australia 1993 Diploma of Obstetrics (Dip Obs) University of Auckland New Zealand 1992 Masters papers in Genetics and Statistics Lincoln University New Zealand -
Research Interests
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Journals
Year Citation 2019 Nisenblat, V., Sharkey, D., Wang, Z., Evans, S., Healey, M., Maria Ohlsson Teague, E., . . . Louise Hull, M. (2019). Plasma miRNAs display limited potential as diagnostic tools for endometriosis. Journal of Clinical Endocrinology and Metabolism, 104(6), 1999-2022.
WoS1 Europe PMC12019 Johan, M. Z., Ingman, W. V., Robertson, S. A., & Hull, M. L. (2019). Macrophages infiltrating endometriosis-like lesions exhibit progressive phenotype changes in a heterologous mouse model. Journal of Reproductive Immunology, 132, 1-8.
WoS12019 Robertson, S. A., Green, E. S., Care, A. S., Moldenhauer, L. M., Prins, J. R., Hull, M. L., . . . Dekker, G. (2019). Therapeutic potential of regulatory T cells in preeclampsia-opportunities and challenges. Frontiers in Immunology, 10(MAR), 478-1-478-18.
Scopus1 WoS12019 Schjenken, J., Panir, K., Robertson, S., & Hull, M. (2019). Exosome-mediated intracellular signalling impacts the development of endometriosis-new avenues for endometriosis research. Molecular human reproduction, 25(1), 2-4.
2018 Evans, S., Brooks, T., Esterman, A., Hull, M., & Rolan, P. (2018). The comorbidities of dysmenorrhea: A clinical survey comparing symptom profile in women with and without endometriosis. Journal of Pain Research, 11, 3181-3194.
Scopus1 WoS12018 Brown, H., Green, E., Tan, T., Gonzalez, M., Rumbold, A., Hull, M., . . . Thompson, J. (2018). Periconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaptation to pregnancy. Scientific reports, 8(1), 2114-1-2114-13.
Scopus5 WoS4 Europe PMC32018 Panir, K., Schjenken, J., Robertson, S. A., & Hull, M. (2018). Non-coding RNA’s in Endometriosis. Human Reproduction Update, 24(4), 497-515.
2018 Nissenblatt, V., & Hull, M. (2018). Ovulation induction: when and how to use it. Endocrinology Today, 7(2), 38-42. 2017 Short, A., & Hull, M. L. (2017). How to treat Paediatric and Adolescent Gynaecology. Australian Doctor, 17-24. 2017 Rogers, P., Adamson, G., Al-Jefout, M., Becker, C., D'Hooghe, T., Dunselman, G., . . . Zondervan, K. (2017). Research priorities for endometriosis: recommendations from a global consortium of investigators in endometriosis. Reproductive Sciences, 24(2), 202-226.
Scopus25 WoS26 Europe PMC152017 Johnson, N., Hummelshoj, L., Adamson, G., Keckstein, J., Taylor, H., Abrao, M., . . . Giudice, L. (2017). World endometriosis society consensus on the classification of endometriosis. Human Reproduction, 32(2), 315-324.
Scopus61 WoS52 Europe PMC252016 Nisenblat, V., Prentice, L., Bossuyt, P. M., Farquhar, C., Hull, M. L., & Johnson, N. (2016). Combination of the non-invasive tests for the diagnosis of endometriosis. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (7), 132 pages.
2016 Nisenblat, V., Prentice, L., Bossuyt, P., Farquhar, C., Hull, M., & Johnson, N. (2016). Combination of the non-invasive tests for the diagnosis of endometriosis. Cochrane Database of Systematic Reviews, 2016(7), 132 pages.
Scopus50 WoS38 Europe PMC172016 Robertson, S., Jin, M., Yu, D., Moldenhauer, L., Davies, M., Hull, M., & Norman, R. (2016). Corticosteroid therapy in assisted reproduction - immune suppression is a faulty premise. Human Reproduction, 31(10), 2164-2173.
Scopus27 WoS26 Europe PMC152016 Moran, L., Spencer, L., Russell, D., Hull, M., Robertson, S., Varcoe, T., . . . Rodgers, R. (2016). Research priorities for fertility and conception research as identified by multidisciplinary health care practitioners and researchers. Nutrients, 8(1), 35-1-35-8.
Scopus12016 Nisenblat, V., Bossuyt, P., Farquhar, C., Johnson, N., & Hull, M. (2016). Imaging modalities for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews, 2016(2), 295 pages.
Scopus86 WoS63 Europe PMC282016 Nisenblat, V., Bossuyt, P., Shaikh, R., Farquhar, C., Jordan, V., Scheffers, C., . . . Hull, M. (2016). Blood biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews, 2016(5), 647 pages.
Scopus63 WoS49 Europe PMC152016 Gupta, D., Hull, M., Fraser, I., Miller, L., Bossuyt, P., Johnson, N., & Nisenblat, V. (2016). Endometrial biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews, 2016(4), 297 pages.
Scopus39 WoS30 Europe PMC182015 Liu, E., Nisenblat, V., Farquhar, C., Fraser, I., Bossuyt, P., Johnson, N., & Hull, M. (2015). Urinary biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database of Systematic Reviews, 2015(12), 95 pages.
Scopus24 WoS12 Europe PMC52015 Pantasri, T., Wu, L., Hull, M., Sullivan, T., Barry, M., Norman, R., & Robker, R. (2015). Distinct localisation of lipids in the ovarian follicular environment. Reproduction, Fertility and Development, 27(4), 593-601.
Scopus9 WoS7 Europe PMC12015 McGuane, J., Watson, K., Zhang, J., Johan, M., Wang, Z., Kuo, G., . . . Hull, M. (2015). Seminal plasma promotes lesion development in a xenograft model of endometriosis. American Journal of Pathology, 185(5), 1409-1422.
Scopus6 WoS6 Europe PMC32014 Becker, C. M., Laufer, M. R., Stratton, P., Hummelshoj, L., Missmer, S. A., Zondervan, K. T., . . . Zondervan, K. (2014). World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research. Fertility and Sterility, 102(5), 1213-1222.
2014 Rahmioglu, N., Fassbender, A., Vitonis, A. F., Tworoger, S. S., Hummelshoj, L., D'Hooghe, T. M., . . . Zondervan, K. (2014). World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research. Fertility and Sterility, 102(5), 1233-1243.
2013 Hull, M., & Nisenblat, V. (2013). Tissue and circulating microRNA influence reproductive function in endometrial disease. Reproductive BioMedicine Online, 27(5), 515-529.
Scopus40 WoS35 Europe PMC212012 Nisenblat, V., Farquhar, C., Akoum, A., Fraser, I., Bossuyt, P., & Hull, M. (2012). Non-invasive tests for the diagnosis of endometriosis. The Cochrane Database of Systematic Reviews, 2012(1), 1-35.
2012 Nakamura, H., Jasper, M., Hull, M., Aplin, J., & Robertson, S. (2012). Macrophages regulate expression of α1,2-fucosyltransferase genes in human endometrial epithelial cells. Molecular Human Reproduction, 18(4), 204-215.
Scopus24 WoS19 Europe PMC102012 Hull, M., Johan, M., Hodge, W., Robertson, S., & Ingman, W. (2012). Host-derived TGFB1 deficiency suppresses lesion development in a mouse model of endometriosis. American Journal of Pathology, 180(3), 880-887.
Scopus36 WoS36 Europe PMC262011 Zhao, Z., Croft, L., Nyholt, D., Chapman, B., Treloar, S., Hull, M., & Montgomery, G. (2011). Evaluation of polymorphisms in predicted target sites for micro RNAs differentially expressed in endometriosis. Molecular Human Reproduction, 17(2), 92-103.
Scopus25 WoS23 Europe PMC172010 Ohlsson Teague, E., Print, C., & Hull, M. (2010). The role of microRNAs in endometriosis and associated reproductive conditions. Human Reproduction Update, 16(2), 142-165.
Scopus178 WoS151 Europe PMC1162009 Hull, M., Nemeth, D., Hague, W., Wilkinson, C., Liebelt, J., Lane, M., & Inglis, D. (2009). Mitochondrial fatty acid transport enzyme deficiency-implications for in vitro fertilization. Fertility and Sterility, 91(6), 11-14.
Scopus2 WoS22009 Ohlsson Teague, E., Van Der Hoek, K., Van der Hoek, M., Perry, N., Wagaarachchi, P., Robertson, S., . . . Hull, M. (2009). MicroRNA-regulated pathways associated with endometriosis. Molecular Endocrinology, 23(2), 265-275.
Scopus214 WoS197 Europe PMC1532008 Hull, M., Escareno, C., Godsland, J., Doig, J., Johnson, C., Phillips, S., . . . Charnock-Jones, S. (2008). Endometrial-peritoneal interactions during endometriotic lesion establishment. American Journal of Pathology, 173(3), 700-715.
Scopus95 WoS91 Europe PMC672006 Hull, M., Gun, M., & Ritossa, M. (2006). Hook-wire insertion facilitates the excision of scar endometriosis. BJOG, 113(6), 744-746.
Scopus2 WoS22005 Hull, M., Prentice, A., Wang, D., Butt, R., Phillips, S., Smith, S., & Charnock-Jones, D. (2005). Nimesulide, a COX-2 inhibitor, does not reduce lesion size or number in a nude mouse model of endometriosis. Human Reproduction, 20(2), 350-358.
Scopus45 Europe PMC302005 Hull, M., & Charnock-Jones, D. (2005). Reply: Is the dose to inhibit the COX-2 enzyme in nude mice also adequate in human endometrial tissues?. Human Reproduction, 20(9), 2665-2666.
2005 Matsuzaki, S., Canis, M., Hull, M., & Charnock-Jone, D. (2005). Is the dose to inhibit the COX-2 enzyme in nude mice also adequate in 'human' endometrial tissues? (multiple letters) [4]. Human Reproduction, 20(9), 2665-2666.
Scopus1 Europe PMC22003 Hull, M., Charnock-Jones, D., Chan, C., Bruner-Tran, K., Osteen, K., Tom, B., . . . Smith, S. (2003). Antiangiogenic agents are effective inhibitors of endometriosis. The journal of Clinical Endocrinology and Metabolism, 88(6), 2889-2899.
Scopus211 Europe PMC1402003 Borthwick, J., Charnock-Jones, D., Tom, B., Hull, M., Teirney, R., Phillips, S., & Smith, S. (2003). Determination of the transcript profile of human endometrium. Molecular human reproduction, 9(1), 19-33.
Scopus262 Europe PMC1482001 Inder, W. J., Prickett, T. C., Ellis, M. J., Hull, L., Reid, R., Benny, P. S., . . . Donald, R. A. (2001). The Utility of Plasma CRH as a Predictor of Preterm Delivery. The Journal of Clinical Endocrinology & Metabolism, 86(12), 5706-5710.
1998 Hull, M., Livesey, J., Evans, J., & Benny, P. (1998). The effect of recombinant follicle stimulating hormone (Gonal-F) on endogenous luteinizing hormone secretion in women. Human Reproduction, 13(5), 1139-1143.
Scopus7 Europe PMC41995 Hull, M., Reid, R., Evans, J., Benny, P., & Aickin, D. (1995). Pre-ovulatory oxytocin administration promotes the onset of the luteinizing hormone surge in human females. Human Reproduction, 10(9), 2266-2269. 1995 Hull, M., Reid, R., Evans, J., Benny, P., & Aickin, D. (1995). Endocrinology: Pre-ovulatory oxytocin administration promotes the onset of the luteinizing hormone surge in human females. Human Reproduction, 10(9), 2266-2269.
Scopus26 Europe PMC91989 Kroencke, M., & Hull, M. (1989). A method for designing multiload component dynamometers incorporating octagonal strain rings. Experimental Mechanics, 29(2), 195-204.
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Book Chapters
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Conference Papers
Year Citation 2010 Hull, M. L. (2010). Macrophages, TGFB superfamily cytokines, micro-RNAs and endometriosis. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 86 (pp. 20). Palm Grove, AUSTRALIA: ELSEVIER IRELAND LTD.
2009 Hull, M. L., Johan, M., & Ingman, W. V. (2009). Host Site TGFB1 Deficiency Constrains Endometriosis-Like Lesion Development. In REPRODUCTIVE SCIENCES Vol. 16 (pp. 101A). Glasgow, SCOTLAND: SAGE PUBLICATIONS INC. -
Conference Items
Year Citation 2013 Johan, M. Z., Ingman, W., Robertson, S., & Hull, M. (2013). Activation Status of Macrophages in Lesions from a MacGreen/SCID Mouse Model of Endometriosis. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2013 McGuane, J. T., Johan, M. Z., Wang, Z., Paterson, E. L., Goodall, G. J., & Hull, M. L. (2013). Stromal Localisation of the miR-99 and-125 microRNA Families in Endometriotic Tissues. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC.
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 Principal Supervisor Evaluating the Contribution of Immune Regulatory Factors in Endometriosis Doctor of Philosophy Doctorate Full Time Miss Kavita Panir 2013 Co-Supervisor Pelvic Pain in Young Women Doctor of Philosophy Doctorate Part Time Dr Susan Evans -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2011 - 2014 Co-Supervisor The Effect of Macrophages on Fibroblast Activity and Lesion Development in Mouse Models of Endometriosis Doctor of Philosophy Doctorate Full Time Mr Mohammad Zahied Johan 2009 - 2013 Co-Supervisor Circulating microRNAs in endometriosis Doctor of Philosophy Doctorate Full Time Dr Victoria Nisenblat -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2018 - 2018 Co-Supervisor Macrophage alterations in microRNA deficient mouse models of endometriosis The University of Adelaide Bachelor of Health and Medical Sciences (Honours) (First Class Honours Award) Honours Full Time Kavita Bikram Shah 2012 - 2012 Principal Supervisor The effect of seminal plasma on endometriosis-like lesion development in the SCID mouse model of endometriosis The University of Adelaide — Honours Full Time Dr Kathryn Watson 2008 - 2008 Principal Supervisor The effects of p38 MAPK inhibitor in an In Vivo model of endometriosis The University of Adelaide — Honours Full Time Mr Mohammed Zahied Johan -
Mentoring
Date Topic Location Name 2018 - ongoing Year 3 Research Proposal The University of Adelaide Georgina Duncan, Emily Marriott, Takshin Fernando, Jude Dejanovic 2017 - ongoing Year 3 research proposal The University of Adelaide Larrisa Au, Vishakha Dissanayake, Jessica Huynh, Natasya Cahyadi 2016 - ongoing Year 3 research proposal The University of Adelaide Madeline Rock, Kathryn Sharley, Jennifer Hughes, Lucy Heyworth 2016 - ongoing Year 3 research proposal The University of Adelaide Soravee Kiranantawat, Cutie Kannampuzha, Si-Lin Ong, Siu-Man Yuen 2014 - ongoing Summer medical student project The University of Adelaide Ms Annette Marden 2013 - ongoing Summer medical student project The University of Adelaide Mr Gabriel Kuo 2007 - ongoing Medical student research project The University of Adelaide Mr Raj Kumar 2007 - ongoing Medical student research project The University of Adelaide Ms Fiona Khoo
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Board Memberships
Date Role Board name Institution name Country 2009 - 2012 Member Fertility SA Fertility SA Australia -
Committee Memberships
Date Role Committee Institution Country 2015 - ongoing Member Scientific Organising Committee for ASPIRE 2016 Congress Asia Pacific Initiative on Reproduction (ASPIRE) — -
Memberships
Date Role Membership Country 2015 - ongoing Treasurer Australian and New Zealand Society of Reproductive Endocrinology and Infertility Australia 2015 - ongoing Representative Endometriosis Awareness — 2012 - ongoing Representative World Endometriosis Society (WES) Australia 2010 - ongoing Member ASRM United States 2008 - ongoing Member Fertility Society of Australia (FSA) Australia 2008 - ongoing Member Australian Gynaecological Endoscopic Society (AGES) Australia 1999 - ongoing Member Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2013 - ongoing Member Faculty of 1000 — — 2010 - 2014 Associate Editor Human Reproduction — —
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External Profiles
