
Associate Professor Louise Hull
Associate Professor
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor Louise Hull has worked in fertility services since she graduated as a doctor in 1991. During this time she has been delighted to help many couples conceive, as well as promote the development of improved fertility treatments through research and education. Professor Louise Hull works at the Robinson Research Institute, University of Adelaide, Women’s and Children’s Hospital, Adelaide and in private practice at Embrace Fertility in North Adelaide https://embracefertility.org/
Professor Louise Hull became an Obstetrician and Gynaecologist (FRANZCOG) after gaining clinical experience working in IVF units in Christchurch, New Zealand, Cambridge, UK and Adelaide, Australia, including Bourn Hall, the fertility centre where the first IVF baby was born. She was awarded the Certificate in Reproductive Endocrinology and Infertility (CREI) sub speciality qualification by RANZCOG in 2006.
Professor Hull completed a PhD s in Endometriosis at the University of Cambridge, UK in 2006. She was appointed to the University of Adelaide in 2006 where she established and led the Endometriosis Group at the Robinson Research Institute. Her research focuses on the basic science of endometriosis, developing new diagnostics for endometriosis and conducting Phase 3 and 4 pharmaceutical trials. She is an international ambassador for the World Endometriosis Society www.endometriosis.ca/about/ambassador/louise-hull, a Medical Advisory Board member for Endometriosis Australia and EndoNZ and participated in the National Action Plan round Table for Endometriosis by invitation from the Minister of Health. She has several national and international collaborations and has been awarded considerable grant money over the last 2 years to further endometriosis research in Australasia.
More recently Professor Louise Hull has conducted research exploring the immunology and biology of implantation and has participated in biotechnology and pharmacology sponsored clinical trials in the IVF industry. She is the deputy clinical leader of the Fertility and Conception Theme at the Robinson Institute, the co-chair of the Special Interest Group for Implantation of ASPIRE and has funding for several research projects exploring recurrent implantation failure and miscarriage.
Professor Louise Hull publishes widely, presents at international conferences, supervises PhD students and teaches reproductive medicine to medical students, registrars and reproductive medicine fellows. She has received numerous grants, fellowships and awards. Additionally, Louise has been an associate editor for Human Reproduction, chaired several grant committees, sits on the Jean Hailes Governance Committee for the endometriosis national action plan and has been on the board of 3 IVF and software companies and 2 pharmaceutical medical advisory boards.
Associate Professor Louise Hull has founded 2 IVF units and in her roles as scientific director and new developments director has been integral in introducing novel treatments, laboratory methods and models of care to the IVF industry. She is currently the Written Exam Chair for the Certificate in Reproductive Endocrinology and Infertility (CREI) subspeciality for RANZCOG and the treasurer of the ANZCREI society.
How to Improve Endometrial Receptivity
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Appointments
Date Position Institution name 2020 - ongoing Head of Discipline of Obstetrics and Gynaecology Faculty of Medicine 2019 - ongoing Founding member and Fertility Subspecialist (CREI) Embrace Fertility 2019 - ongoing Founding member and Fertility Sub specialist Embrace Fertility 2018 - ongoing Governance Commitee Member Jean Hailes Foundation fro Women's Health NGO 2017 - ongoing Consultant Fertility Specialist O & G 2017 - ongoing Leader Fertility and Conception Theme Robinson Research Insitiute 2015 - ongoing Board Member Genea Oxford Fertility 2015 - ongoing Board Member FAB Software Ltd 2015 - ongoing Assoc Prof and Group Leader of the Endometriosis Research Group, The Robinson Research Institute, Research Centre for Reproductive Health , University of Adelaide 2015 - ongoing Staff Specialist Gynaecologist Women's and Children's Hospital 2011 - 2017 New Developments Director Fertility SA 2009 - 2018 Consultant Fertility Specialist Fertility SA 2009 - 2012 Board Member Fertility SA 2009 - 2010 Scientific Director Fertility SA 2009 - ongoing Founding Member Fertility SA 2008 - 2014 Senior Lecturer University of Adelaide 2008 - 2009 Fertility Consultant Repromed 2004 - 2008 Clinical Lecturer University of Adelaide 2004 - 2007 Subspecialist Trainee in Clinical Reproductive Endocrinology and Infertility (CREI) Repromed 2004 - 2007 Fertility Consultant Repromed 2000 - 2004 Research Associate and PhD candidate University of Cambridge 2000 - 2004 Specialist Registrar in Reproductive Medicine, Senior Specialist Registrar (NTN training position East Anglia Deanery) The Rosie Hospital 2000 - 2000 Locum Registrar Royal Free Hospital 1998 - 1999 Senior Registrar Tauton and Sommerset Hospital 1995 - 1998 Registrar Christchurch Women’s Hospital 1993 - 1995 Medical Officer of Special Scale Christchurch Women’s Hospital 1992 - 1992 Senior House Officer Nelson Hospital 1991 - 1992 House Officer Christchurch Public Hospital -
Awards and Achievements
Date Type Title Institution Name Country Amount 2016 Award Paper of the Month Robinson Research Institute Australia 2015 Award Institute Paper of the Month Robinson Research Institute Australia 2014 Teaching Award Professor Derek Frewin AO Citation for Clinical Teaching University of Adelaide Australia 2014 Award Top 10% of reviewers Human Reproduction Update Australia 2014 Award Top 10% of reviewers Human Reproduction Australia 2014 Invitation Invited member of the Faculty of 1000 Faculty of 1000 Australia 2013 Invitation Invited International Ambassador for the World Endometriosis Society World Endometriosis Society Australia 2012 Award Professor Derek Frewin AO Citation for Clinical Teaching University of Adelaide Australia 2009 Award Best original scientific paper Research Centre for Reproductive Medicine Australia 2008 Award Best scientific paper, 10th World Congress of Endometriosis 10th World Congress of Endometriosis Australia 2008 Award Best scientific paper 10th World Congress of Endometriosis Australia 2004 Fellowship Burrough’s Welcome Travel Fellowship Society for Gynaecological Investigation United States 1998 Award Runner up best presentation South West Obstetrics and Gynaecology Training Group United Kingdom 1995 Award Immigrant Young Investigator Award NZ Medical Women’s Association Harvey Carey Memorial prize for best presentation New Zealand 1989 Distinction Distinction in Obstetrics and Gynaecology University of Otago New Zealand 1988 Distinction Basic Science and Clinical Science University of Otago New Zealand -
Education
Date Institution name Country Title 2016 - 1991 Christchurch School of Medicine, University of Otago New Zealand MBChB 2003 - 2006 University of Cambridge United Kingdom PhD 1983 - 1986 University of Otago New Zealand BSc (Biochemistry and Microbiology) -
Postgraduate Training
Date Title Institution Country 2017 Certificate of Completion, Higher Education Academic Staff Leadership Colloquium Online National Excellence in Educational leadership Initiative (NEELI) Australia 2012 Graduate of the Australian Institute of Company Directors (GAICD) Australian Institute of Company Directors Australia 2012 Certificate of Reproductive Endocrinology and Infertility (CREI) Royal Australian and New Zealand College of Obstetricians and Gynaecologists Australia 2006 Fellowship Royal Australian and New Zealand College of Obstetricians and Gynaecologists Australia 1999 Diploma of Fertility and Family Planning (DFFP) Royal College of Obstetricians and Gynaecologists (RCOG) United Kingdom 1999 Fellow (FRANZCOG) Royal Australian and New Zealand College of Obstetricians and Gynaecologists Australia 1993 Diploma of Obstetrics (Dip Obs) University of Auckland New Zealand 1992 Masters papers in Genetics and Statistics Lincoln University New Zealand -
Research Interests
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Journals
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Book Chapters
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Conference Papers
Year Citation 2019 Panir, K., Schjenken, J. E., Breen, J., Greaves, E., Robertson, S. A., & Hull, M. L. (2019). Lesion Development in Endometriosis is Regulated by miR-223 Mediated Macrophage Activity.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 375A-376A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2010 Hull, M. L. (2010). Macrophages, TGFB superfamily cytokines, micro-RNAs and endometriosis. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 86 (pp. 20). Palm Grove, AUSTRALIA: ELSEVIER IRELAND LTD.
2009 Hull, M. L., Johan, M., & Ingman, W. V. (2009). Host Site TGFB1 Deficiency Constrains Endometriosis-Like Lesion Development. In REPRODUCTIVE SCIENCES Vol. 16 (pp. 101A). Glasgow, SCOTLAND: SAGE PUBLICATIONS INC. 2004 Hull, M. L., Borthwick, J. M., Gardner, C., Butt, R. P., Phillips, S. C., Smith, S. K., & Charnock-Jones, D. S. (2004). Identification of peritoneal and endometrial transcript profiles in a nude mouse model of endometriosis.. In JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION Vol. 11 (pp. 186A). Houston, TX: ELSEVIER SCIENCE INC. -
Conference Items
Year Citation 2013 Johan, M. Z., Ingman, W. V., Robertson, S. A., & Hull, M. L. (2013). Activation Status of Macrophages in Lesions from a MacGreen/SCID Mouse Model of Endometriosis. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2013 McGuane, J. T., Johan, M. Z., Wang, Z., Paterson, E. L., Goodall, G. J., & Hull, M. L. (2013). Stromal Localisation of the miR-99 and-125 microRNA Families in Endometriotic Tissues. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC.
RESEARCH SUPPORT
GRANTS
2020 |
Commercial Partnership with Guerbet The biological effects of oil contrast media for tubal flushing Principle Investigator: Sarah Robertson Co-investigators: M.louise Hull, Neil Johnson, Lachlan Mouldenhauer |
$640,000 over 3 years |
2019 |
Pharmaceutical Trial with Bayer DARE study to assess vaginal combined HRT ring |
$130,000 over 1 year |
MRFF Grant Project Sep 2019 – Sep 2022 Project: Digital Platform for Endometriosis Principle Investigator: M. Louise Hull |
$1,200,000 over 3 years |
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Australasian Gynaecological and Endoscopic Research Grant Project: Machine learning using ultrasound and MRI scans in the diagnosis of endometriosis. Principle Investigator: M. Louise Hull |
$9570 over one year | |
Pharmaceutical Trial with MERC MKT 4326 in pain management in endometriosis Principle Investigator: M. Louise Hull |
$10,000 |
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Pharmaceutical Trial with Myovant Project: Relagolix in the treatment of endometriosis Principle Investigator: M. Louise Hull |
$86,000 |
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NHMRC Grant Project -Jan 2019- Dec 2021 Project: The magic shield of the human uterus and fate of embryo implantation Grant ID: APP1156666 CIA: Guying Nie CIB: Luk Rhombauts CIC: Louise Hull |
$ 749,000 over 3 years |
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2018 |
Australasian Gynaecological and Endoscopic Research Grant Project: Surgical and medical management of miscarriage and genetic diagnosis. Principle Investigator: M. Louise Hull |
$28,000 over 1 year |
Women’s and Children’s Foundation Grant Anti-Mullerian Hormone Isoforms in the Diagnosis of Adolescents with Polycystic Ovarian Syndrome. CIA: Alexia Pena CIB: Erandi Hewawasam CIC: Michael Pankhurst CID: Louise Hull CIE: Asha Short |
$71,000 | |
Women’s and Children’s Foundation Grant Project: Comparison of models of care for delivering pelvic floor physiotherapy for chronic pelvic pain CIA: Kate Goode CIB: Tamara McNamara CIC Louise Hull |
$34,000 | |
Women and Children’s Foundation Grant Project: Comparison of Karyotype and CGH arrays for genetic diagnosis of products of conception after medical and surgical miscarriage CIA: Louise Hull CIB: Sarah Linsthwaite CIC: Catherine McCormack CID: Clare Roberts CIE:, Sarah Robertson CIF: Wendy Walters CIG: Emma Knight |
$30,000 | |
2016 |
Engaging Opportunities Program, Robinson Research Institute Project: ‘Developing a smart-phone sperm motility assessment tool’ CIA: J Thompson CIB: ML Hull CIC: T Fullston |
$9,500 |
2015 |
NHMRC Project Grant Jan 2015 – Dec 2017 Project: The ‘hostile’ reproductive tract – pro-apoptotic cytokines in infertility, embryo programming and offspring health. Grant ID: APP1079150 CIA: SA Robertson CIB: J Thompson CIC: H Brown AIA: C Sjoblom AIB: L Sedger AIC: M Sirard AID: ML Hull AIE: M Brannstrom AIF: SJ Bent AIG: W Yeung |
$595,810 over 3 years |
The DA and JS Ballantyne Medical and Surgical Research Trust Grant Project: Macrophages in Endometriosis |
$50,660 over 1 year | |
The DA and JS Ballantyne Medical and Surgical Research Trust Grant Project: MiRNA deficient mouse models of endometriosis |
$128,000 over 5 years | |
AGES Research Grant Project: Determining the prevalence and fertility outcomes in couples undertaking IVF when the female partner has ultrasongraphically defined endometriosis. |
$15,000 | |
Investment for Success, Robinson Research Insitute Project: microRNA regulation of macrophages – a causal pathway to endometriosis. |
$28,200 | |
2014 |
BlastGen trial, Origio Randomised controlled trial of BlastGen media |
$31,000 |
2013 |
Solstice Trial, Abbvie Randomised controlled trial of Egalotrix in Endometriosis |
$250,000 over 18 months |
Investment for Success, Robinson Research Institute Project: microRNA deficiency in Endometriosis | $22,000 | |
The Australian Endoscopic Gynaecological Society Grant Project: Bone Pathways in Endometriosis |
$12,000 | |
2012 |
NHMRC Project Grant Jan 2012 – Dec 2014 Project: Seminal fluid and activating T cell tolerance for pregnancy success Grant ID: GNT1028205 CIA: SA Robertson CIB: L Moldenhauer CIC: G Dekker AIA: D Sharkey AIB: J Hayball AIC: ML Hull AID: S Barry |
$481,417 over 3 years |
The DA and JS Ballantyne Medical and Surgical Research Trust Grant Project: microRNAs in Endometriosis |
$97,000 over 1 year | |
Commercial Funding – Bioinnovation SA (now BioSA) Project: Plasma Diagnostic Test Development for Endometriosis |
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2011 |
NHMRC Project Grant Jan 2011 – Dec 2013 Project: TGFB1 is a pivotal regulator of endometriotic lesion development Grant ID: GNT1012950 CIA: ML Hull CIB: WV Ingman AIA: SA Robertson AIB: MJ Jasper AIC: GG Goodall |
$496,000 over 3 years |
The Australian Endoscopic Gynaecological Society Grant Project: microRNAs as a diagnostic tool for Endometriosis |
$17,000 over 2 years | |
The DA and JS Ballantyne Medical and Surgical Research Trust Grant Project: MicroRNAs in Endometriosis |
$48,381 over 1 year | |
2010 |
Fertility Society of Australia Serum MicroRNAs as a Diagnostic Test for Endometriosis |
$30,000 over 1 year |
2009 |
SEED Funding Grant Department of Obstetrics and Gynaecology, The University of Adelaide |
$40,000 over 1 year |
2008 |
Women’s and Children’s Hospital Research Grant The role of Host-derived TGFB in the Establishment of Endometriotic Lesions |
$48,138 over 1 year |
2007 |
The DA and JS Ballantyne Medical and Surgical Research Trust Grant Project: MicroRNAs in Endometriosis |
$150,000 over 3 years |
Women’s and Children’s Hospital Research Grant Project: Tissue Remodelling in Endometriosis |
$48,138 over 1 year | |
2006 |
A Clinical Investigator for the TRUST Clinical Trial Phase 3 Multicentre Trial at REPROMED sponsored by Organon assessing immunogenicity and clinical outcomes of Long Acting FSH |
$250,000 over 3 years |
Colin Matthew’s Grant 2006 | $12,000 | |
TOTAL | $5,873,774 |
RESEARCH FELLOWSHIPS
2010-2015 |
SA Health Early to Mid-Career Clinical Practitioner Fellowship ($90,000 per year for 5 years) |
2005-2007 |
The Arthur Wilson Memorial Fellowship, RANZCOG ($30,000 per year for 2 years) |
2001-2004 | Overseas and Commonwealth Fellowship, St Edmunds College |
2001-2004 | Research Fellowship – sponsored by Pfizer (£2,000 per year) |
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2021 Co-Supervisor Imagendo: Diagnosing endometriosis with imaging and AI Doctor of Philosophy Doctorate Full Time Ms Yuan Zhang 2020 Principal Supervisor Co-creation and evaluation of a digital health platform for endometriosis using Design Thinking Doctor of Philosophy Doctorate Full Time Diksha Sirohi 2019 Principal Supervisor Mechanisms of Action of Lipiodol in Women Undergoing Reproductive Therapy Doctor of Philosophy Doctorate Part Time Mr Faizz Fattah -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2019 Principal Supervisor The contribution of immune regulatory MicroRNAs in endometriosis Doctor of Philosophy Doctorate Full Time Miss Kavita Panir 2013 - 2021 Co-Supervisor Investigations into the Lived Experience and Aetiology of Dysmenorrhoea and Pelvic Pain in Young Women Doctor of Philosophy Doctorate Part Time APrf Susan Evans 2011 - 2014 Co-Supervisor The Effect of Macrophages on Fibroblast Activity and Lesion Development in Mouse Models of Endometriosis Doctor of Philosophy Doctorate Full Time Mr Mohammad Zahied Johan 2009 - 2013 Co-Supervisor Circulating microRNAs in endometriosis Doctor of Philosophy Doctorate Full Time Dr Victoria Nisenblat -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2018 - 2018 Co-Supervisor Macrophage alterations in microRNA deficient mouse models of endometriosis The University of Adelaide Bachelor of Health and Medical Sciences (Honours) (First Class Honours Award) Honours Full Time Kavita Bikram Shah 2012 - 2012 Principal Supervisor The effect of seminal plasma on endometriosis-like lesion development in the SCID mouse model of endometriosis The University of Adelaide Honours Full Time Dr Kathryn Watson 2008 - 2008 Principal Supervisor The effects of p38 MAPK inhibitor in an In Vivo model of endometriosis The University of Adelaide Honours Full Time Mr Mohammed Zahied Johan -
Mentoring
Date Topic Location Name 2018 - ongoing Year 3 Research Proposal The University of Adelaide Georgina Duncan, Emily Marriott, Takshin Fernando, Jude Dejanovic 2017 - ongoing Year 3 research proposal The University of Adelaide Larrisa Au, Vishakha Dissanayake, Jessica Huynh, Natasya Cahyadi 2016 - ongoing Year 3 research proposal The University of Adelaide Madeline Rock, Kathryn Sharley, Jennifer Hughes, Lucy Heyworth 2016 - ongoing Year 3 research proposal The University of Adelaide Soravee Kiranantawat, Cutie Kannampuzha, Si-Lin Ong, Siu-Man Yuen 2014 - ongoing Summer medical student project The University of Adelaide Ms Annette Marden 2013 - ongoing Summer medical student project The University of Adelaide Mr Gabriel Kuo 2007 - ongoing Medical student research project The University of Adelaide Mr Raj Kumar 2007 - ongoing Medical student research project The University of Adelaide Ms Fiona Khoo
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Board Memberships
Date Role Board name Institution name Country 2009 - 2012 Member Fertility SA Fertility SA Australia -
Committee Memberships
Date Role Committee Institution Country 2015 - ongoing Member Scientific Organising Committee for ASPIRE 2016 Congress Asia Pacific Initiative on Reproduction (ASPIRE) -
Memberships
Date Role Membership Country 2015 - ongoing Treasurer Australian and New Zealand Society of Reproductive Endocrinology and Infertility Australia 2015 - ongoing Representative Endometriosis Awareness 2012 - ongoing Representative World Endometriosis Society (WES) Australia 2010 - ongoing Member ASRM United States 2008 - ongoing Member Fertility Society of Australia (FSA) Australia 2008 - ongoing Member Australian Gynaecological Endoscopic Society (AGES) Australia 1999 - ongoing Member Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2013 - ongoing Member Faculty of 1000 2010 - 2014 Associate Editor Human Reproduction
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