Professor Christopher Rayner
Professor
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor Christopher Rayner MBBS, PhD, FRACP
Gwendolyn Michell Professor
Gastroenterologist
Chris Rayner is a Professor in the Adelaide Medical School, University of Adelaide, and a Consultant Gastroenterologist at the Royal Adelaide Hospital, South Australia. His major research interest concerns nutrient-gut interactions, including the regulation of gastrointestinal motility, with an emphasis on the role of upper gut function in diabetes. His key contributions have been to develop an understanding of the mechanisms of glucose sensing and incretin hormone release in the gut, and how these can be manipulated for therapeutic gain. He has developed the concept of protein preloads, taken in advance of meals, to initiate gut feedback mechanisms that will lower subsequent postprandial glycaemia in type 2 diabetes. He is a Chief Investigator in an NHMRC Centre of Research Excellence in Translating Nutritional Science to Good Health, based at the University of Adelaide.
Special Interests
Professor Chris Rayner works closely with Prof Michael Horowitz and Prof Karen Jones in a group that has a well-established program of research focussing on gastrointestinal function in diabetes. We work within a Centre of Research Excellence in Translating Nutritional Science to Good Health, established with NHMRC funding in 2007, which is a focal point for researchers who have an interest in nutrition and gut function, particularly in the areas of diabetes, obesity, critical illness, and aging.
Current projects include:
- Role of the incretin hormone glucose-dependent insulinotropic polypeptide (GIP) in health and type 2 diabetes, using a human GIP receptor antagonist - in collaboration with Dr Simon Veedfald/Prof Jens Holst (University of Copenhagen)
- Comparison of intravenous and subcutaneous routes of infusion of the incretin hormone glucagon-like peptide 1 (GLP-1) in type 2 diabetes - in collaboration with Dr Daniel Quast/Prof Juris Meier/Prof Michael Nauck (Ruhr University Bochum)
- Role of the sweet taste receptor in the small intestine – in collaboration with A/Prof Richard Young (SAHMRI)
- Intestinal bitter taste receptors as a potential treatment target for type 2 diabetes – in collaboration with Dr Tongzhi Wu
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Appointments
Date Position Institution name 2015 - ongoing Gwendolyn Michell Professor University of Adelaide 2008 - 2014 Associate Professor University of Adelaide 2004 - ongoing Consultant Gastroenterologist Royal Adelaide Hospital 2004 - 2007 Senior Lecturer University of Adelaide 2002 - 2004 Post-doctoral Research Fellow St Mark’s Hospital, London 2000 - 2001 Senior Registrar in Gastroenterology Royal Adelaide Hospital 1997 - 1999 Affiliate Registrar in Gastroenterology Royal Adelaide Hospital 1997 - 1999 Research Fellow Royal Adelaide Hospital 1996 - 1996 Advanced Physician Trainee Royal Adelaide Hospital 1993 - 1996 Basic Physician Trainee Royal Adelaide Hospital 1992 - 1992 Intern Royal Adelaide Hospital -
Education
Date Institution name Country Title 2001 University of Adelaide Australia Doctor of Philosophy (PhD) 1992 University of Adelaide Australia Bachelor of Medicine and Bachelor of Surgery (with Honours) -
Research Interests
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Journals
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Book Chapters
Year Citation 2024 Rayner, C. K., Jones, K. L., & Horowitz, M. (2024). Diabetes and the Gut. In S. Rao, H. Parkman, & R. McCallum (Eds.), Handbook of Gastrointestinal Motility and Functional Disorders (pp. 291-302). CRC Press.
DOI2023 Rayner, C. K., Jones, K. L., & Horowitz, M. (2023). Diabetes and the gut. In S. S. C. Rao, H. P. Parkman, & R. W. McCallum (Eds.), Handbook of Gastrointestinal Motility and Disorders of Gut-Brain Interactions, Second Edition (2 ed., pp. 331-343). Elsevier.
DOI2022 Rayner, C. K., & Horowitz, M. (2022). Changes in gastrointestinal motor and sensory function associated with ageing. In Pathy's Principles and Practice of Geriatric Medicine (pp. 231-246). Wiley.
DOI2020 Rayner, C. K., & Horowitz, M. (2020). Gastrointestinal MotilityDisturbances in the Elderly. In Gastrointestinal Tract in the Aged (pp. 23-42). 2020 Rayner, C. K., Jones, K. L., & Horowitz, M. (2020). Diabetic gastroparesis. In Gastroparesis: Pathophysiology, Clinical Presentation, Diagnosis and Treatment (pp. 237-253). Elsevier.
DOI Scopus22019 Marathe, C. S., Rayner, C. K., Wu, T., Jones, K. L., & Horowitz, M. (2019). Diabetes and the Gastrointestinal Tract. In Encyclopedia of Gastroenterology, Second Edition (pp. 9-12). Elsevier.
DOI2019 Rayner, C. K., & Chapman, M. J. (2019). Nutrition and Parenteral Nutrition. In M. Wichmann, T. McCullough, I. Roberts-Thomson, & G. Maddern (Eds.), Gastroenterology For General Surgeons (pp. 215-228). Springer International Publishing.
DOI2017 Watson, L., Wu, T., Horowitz, M., & Rayner, C. (2017). Whey Protein and Diabetes. In R. Watson, R. Collier, & V. Preedy (Eds.), Dairy in Human Health and Disease across the Lifespan (pp. 197-209). United Kingdom: Academic Press.
DOI Scopus22016 Wu, T., Rayner, C., & Horowitz, M. (2016). Incretins. In S. Herzig (Ed.), Metabolic Control (Vol. 233, pp. 137-171). Switzerland: Springer.
DOI Scopus54 Europe PMC252015 Rayner, C. K., Jones, K. L., & Horowitz, M. (2015). Diabetes and the gut.. In S. S. C. Rao, H. P. Parkman, & R. W. McCallum (Eds.), Handbook of Gastrointestinal Motility and Functional Disorders (1 ed., pp. 283-294). Slack Incorporated. 2012 Rayner, C., Hebbard, G., & Horowitz, M. (2012). Physiology of the antral pump and gastric emptying. In L. Johnson (Ed.), Physiology of the Gastrointestinal Tract, Volume 1, Fifth Edition (Vol. 1, 5 ed., pp. 959-976). United Kingdom: Elsevier.
DOI Scopus72012 Rayner, C., Jones, K., & Horowitz, M. (2012). Diabetic Gastroparesis. In H. Parkman, & R. McCallum (Eds.), Gastroparesis: Pathophysiology, Presentation and Treatment (1 ed., pp. 177-190). New York: Springer.
DOI2012 Rayner, C. K., & Horowitz, M. (2012). Changes in gastrointestinal motor and sensory function associated with ageing. In A. J. Sinclair, J. E. Morley, & B. Vellas (Eds.), Pathy's principles and practice of geriatric medicine, Volume 1 & 2 (Vol. 1, 5 ed., pp. 247-263). John Wiley & Sons.
DOI2012 Rayner, C. K., Hebbard, G. S., & Horowitz, M. (2012). Physiology of the Antral Pump and Gastric Emptying. In Physiology of the Gastrointestinal Tract, Two Volume Set (pp. 959-976).
DOI Scopus12011 Rayner, C. K., & Horowitz, M. (2011). Gastrointestinal motility disturbances in the elderly. In Malnick, Stephen D.H. Tal, Sari (Ed.), Gastrointestinal Tract in the Aged (pp. 23-42). Nova Science Publishers. 2010 Wu, T., Rayner, C. K., Jones, K., & Horowitz, M. (2010). Dietary Effects on Incretin Hormone Secretion. In Vitamins & Hormones (pp. 81-110). Elsevier.
DOI2007 Rayner, C. K., & Horowitz, M. (2007). Upper gastrointestinal complaints. In Edition (pp. 443-461). 2005 Rayner, C., & Horowitz, M. (2005). Aging and the gastrointestinal tract. In The Merck Manual of Geriatrics (4th Edition) (pp. 1000). Whitehouse Station, N.J: Merck. 2005 Rayner, C., & Horowitz, M. (2005). Changes in gastrointestinal motor and sensory function associated with aging. In Principles and Practice of Geriatric Medicine, Volume 1 (pp. 357-370). Chichester: Wiley.
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Conference Papers
Year Citation 2024 Portmann, L., Bryant, R., Raja, S., Rayner, C., Telfer, K., Costello, S., & Day, A. (2024). Comprehensive dietitian-delivered dietary advice effectively achieves dietary change in adults with Ulcerative Colitis, whereas generalised written dietary advice does not. In JOURNAL OF CROHNS & COLITIS Vol. 18 (pp. I1527). OXFORD UNIV PRESS. 2023 Schubert, J., Tay, A., Lee, K. H. C., Leong, L., Rayner, C., Warner, W., . . . Bryant, R. (2023). Genomic analysis of Helicobacter pylori in Australia: Antimicrobial resistance, phylogenetic patterns, and virulence mutations. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 38 (pp. 221). Australia: WILEY.
DOI2023 Lim, A. H. W., Singhal, N., Bartholomeusz, D., Naidu, J., Zobel, J., Hsieh, W., . . . Nguyen, N. Q. (2023). Outcomes of phosphorus-32 microparticle intratumoral implantation added to chemotherapy in patients with metastatic pancreatic adenocarcinoma. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 38 (pp. 25). WILEY.
DOI2023 Bannon, C., Wilson, J. M., Verdino, P., Burling, K., Kay, R. G., Wu, T., . . . Gribble, F. (2023). DETERMINANTS OF PLASMA INSULIN-LIKE 5 LEVELS IN HUMANS AND EFFECT OF RECTAL BILE ACID EXPOSURE. In GASTROENTEROLOGY Vol. 164 (pp. S559). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC. 2023 Sun, Y., Luo, Y., Xiang, C., Xie, C., Ma, J., Sun, Z., . . . Wu, T. (2023). Gastric emptying is accelerated in newly diagnosed type 2 diabetes patients, and is slowed with insulin pump therapy. In DIABETES RESEARCH AND CLINICAL PRACTICE Vol. 197 (pp. 1 page). ELSEVIER IRELAND LTD.
DOI2022 Lu, A., Bound, M., Wu, T., Blefari, C., Horowitz, M., Rayner, C., & Jones, K. (2022). The effect of eight weeks' treatment with the short-acting GLP-1 agonist, lixisenatide, on postprandial blood pressure and heart rate in patients with type two diabetes - A secondary quantitative study. In INTERNAL MEDICINE JOURNAL Vol. 52 (pp. 39-40). WILEY. 2022 Lepore, A., Jenkins, A., Januszewski, A., Lange, K., Hatzinikolas, S., Jalleh, R., . . . Jones, K. (2022). Effect of the short-acting GLP-1 agonist, lixisenatide, on markers of inflammation and oxidative stress in health and type 2 diabetes. In INTERNAL MEDICINE JOURNAL Vol. 52 (pp. 20). WILEY. 2022 Quast, D. R., Xie, C., Bound, M. J., Grivell, J., Jones, K. L., Horowitz, M., . . . Wu, T. (2022). Effects of acute and sub-chronic treatment with metformin on post-prandial blood pressure and heart rate in diet-controlled type 2 diabetes. In DIABETOLOGIA Vol. 65 (pp. S319-S320). Stockholm, SWEDEN: SPRINGER. 2022 Li, T., Zhu, W., Sun, Z., Rayner, C., Young, R., & Wu, T. (2022). SGLT2 inhibition prevents high fat diet-induced glucose intolerance, but not weight gain, in C57BL/6 male mice. In DIABETOLOGIA Vol. 65 (pp. S257-S258). SPRINGER. 2022 Schubert, J. P., Ingram, P., Warner, M. S., Rayner, C. K., Costello, S. P., & Bryant, R. V. (2022). Levofloxacin-resistant Helicobacter pylori in Australia: A growing issue for refractory infection. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 37 (pp. 200-201). WILEY. 2021 Schubert, J. P., Woodman, R. J., Mangoni, A. A., Rayner, C. K., Roberts-Thomson, I. C., Costello, S., & Bryant, R. V. (2021). Geospatial analysis of Helicobacter pylori infection in the Greater Adelaide region over 20 years: Should location influence choice of eradication therapy?. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 36 (pp. 137-138). Virtual online: WILEY. 2018 Borg, M. J., Rayner, C. K., Horowitz, M., Jones, K. L., & Wu, T. (2018). Metformin attenuates the fall in postprandial blood pressure and slows gastric emptying in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S112). Berlin, GERMANY: SPRINGER. 2018 Pham, H., Trahair, L., Phillips, L., Rayner, C. K., Horowitz, M., & Jones, K. L. (2018). Acute effects of the combination of acarbose and gastric distension, with a water preload, on the postprandial blood pressure response to oral sucrose. In DIABETOLOGIA Vol. 61 (pp. S537). Berlin, GERMANY: SPRINGER. 2018 Trahair, L. G., Nauck, M. A., Wu, T., Buttfield, M. D. M., Stevens, J. E., Hatzinikolas, S., . . . Jones, K. L. (2018). Measurement of gastric emptying using scintigraphy and a C-13-octanoic acid breath test with Wagner-Nelson analysis in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S338-S339). Berlin, GERMANY: SPRINGER.
WoS22018 Du, Y. T., Piscitelli, D., Ahmad, S., Trahair, L. G., Greenfield, J. R., Samocha-Bonet, D., . . . Jones, K. L. (2018). Effects of glutamine on gastric emptying of low- and high-nutrient drinks in healthy young subjects: impact on glycaemia. In DIABETOLOGIA Vol. 61 (pp. S335). Berlin, GERMANY: SPRINGER. 2018 Rayner, C. K., Watson, L. E., Phillips, L. K., Bound, M. J., Grivell, J., Wu, T., . . . Natali, A. (2018). Effects of sustained treatment with lixisenatide on gastric emptying and glucose metabolism in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S386-S387). Berlin, GERMANY: SPRINGER. 2016 Marathe, C., Trahair, L., Standfield, S., Rayner, C., Feinle-Bisset, C., Horowitz, M., & Jones, K. (2016). Load-dependent effects of small intestinal glucose on glycaemia, insulinaenia and incretin hormone release in obese subjects. In Abstracts of the 52nd Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia Vol. 59 (pp. S34). Munich, GERMANY: Springer-Verlag.
DOI2016 Selvanderan, S. P., Summers, M., Finnis, M., Plummer, M., Abdelhamid, Y. A., Anderson, M., . . . Deane, A. M. (2016). Administration of Stress Ulcer Prophylaxis May Cause Harm in Critically Ill Patients: A Randomized Double Blind Exploratory Study. In GASTROENTEROLOGY Vol. 150 (pp. S882). San Diego, CA: W B SAUNDERS CO-ELSEVIER INC.
DOI WoS12015 Horowitz, M., Aroda, V., Han, J., Hardy, E., & Rayner, C. (2015). Upper and/or lower GI adverse events with long- vs short-acting GLP-1 receptor agonists: incidence, co-incidence, effects on HbA<sub>1c</sub> and weight. In DIABETOLOGIA Vol. 58 (pp. S7). Stockholm, SWEDEN: SPRINGER.
WoS32015 Marathe, C., Thazhath, S. S., Wu, T., Horowitz., Jones, K. L., & Rayner, C. K. (2015). Effects of Glucagon-like peptide -1 (GLP-1) receptor agonist, exenatide, on small intestinal motility, and glucose absorption in health and type 2 diabetes. In Diabetes. Adelaide. 2015 Marathe, C., Thazhath, S. S., Wu, T., Horowitz, M., Jones, K. L., & Rayner, C. K. (2015). Effects of glucagon-like peptide -1 (GLP-1) receptor agonist, exenatide, on blood pressure and heart rate during duodenal glucose infusion in type 2 diabetes. In Diabetes. Adelaide. 2015 Marathe, C., Horowitz, M., Bound, M., Jones, K. L., & Rayner, C. K. (2015). Relationships of early and late glycaemic responses with gastric emptying during an oral glucose tolerance test. In Diabetes. Adelaide. 2014 Marathe, C., Horowitz, M., Jones, K. L., & Rayner, C. K. (2014). Ethnic variation in insulin and incretin responses to intraduodenal glucose in healthy humans. In Diabetes. San Francisco. 2014 Nguyen, N. Q., Debreceni, T. L., Bambrick, J. E., Chia, B., Wishart, J. M., Deane, A. M., . . . Young, R. L. (2014). Accelerated Glucose Absorption in Proximal Intestine and Its Relationship to Glucose Transporters, Incretin Hormones and Glycaemia in Morbidly Obese Humans: the "X-Factor" of the Foregut Theory?. In GASTROENTEROLOGY Vol. 146 (pp. S108). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC. 2014 Marathe, C., Bound, M., Standfield, S., Wishart, J., Jones, K. L., Horowitz, M., & Rayner, C. K. (2014). Ethnic Variation in the Secretion of Insulin and Incretin Hormones Following Intraduodenal Glucose Infusion in Healthy Humans. In DIABETES Vol. 63 (pp. A456). AMER DIABETES ASSOC. 2014 Nguyen, N. Q., Debreceni, T. L., Bambrick, J. E., Chia, B., Wishart, J. M., Wittert, G. A., . . . Young, R. L. (2014). Impact of a 2-Week Very Low Calorie Diet (VLCD) on Glucose Sensing, Absorption, Transporters, Incretin Hormones and Glycemia in Morbidly Obese Humans. In GASTROENTEROLOGY Vol. 146 (pp. S899). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC. 2013 Thazhath, S. S., Bound, M. J., Jones, K., Horowitz, M., & Rayner, C. (2013). Effect of Hydroxycitric Acid on the Glycemic Response to a Small Intestinal Glucose Load in Healthy Humans. In GASTROENTEROLOGY Vol. 144 (pp. S473). FL, Orlando: W B SAUNDERS CO-ELSEVIER INC. 2013 Nguyen, N. Q., Debreceni, T. L., Burgstad, C. M., Bellon, M., Wishart, J. M., Rayner, C., & Horowitz, M. (2013). Whey Protein Pre-Load Attenuates Post-Prandial Hyperglycemia and Slows Carbohydrate Absorption in Patients With Roux-en-Y Gastric Bypass. In GASTROENTEROLOGY Vol. 144 (pp. S268). W B SAUNDERS CO-ELSEVIER INC. 2013 Lee, M., Umapathysivam, M., Deane, A. M., Chapman, M., Sundararajan, K., Fraser, J., . . . Rayner, C. K. (2013). The Effect of Exogenous GIP in Combination With GLP-1 on Glycaemia in Critically Ill Patients. In DIABETES Vol. 62 (pp. A259). AMER DIABETES ASSOC. 2013 Umapathysivam, M. M., Lee, M. Y., Jones, K. L., Annink, C., Cousins, C. E., Sardana, R., . . . Deane, A. M. (2013). The Effect of Prolonged Glucagon-Like Peptide-1 Receptor Stimulation on Gastric Emptying and Glycemia. In DIABETES Vol. 62 (pp. A265-A266). AMER DIABETES ASSOC. 2013 Marathe, C., Rayner, C., Jones, K. L., & Horowitz, M. (2013). The magnitude of the incretin effect is dependent on the small intestinal glucose load in type 2 diabetes.. In Diabetes. Chicago. 2013 Marathe, C., Feinle-Bisset, C., Bound, M., Standfield, S., Jones, K. L., Horowitz, M., & Rayner, C. (2013). Effect of Rate of Duodenal Glucose Delivery on the "Oral" Disposition Index in Health and Type 2 Diabetes. In DIABETES Vol. 62 (pp. A479). AMER DIABETES ASSOC. 2013 Little, T., Heruc, G., Luscombe-Marsh, N., Bartlett, B., Feinle-Bisset, C., Rayner, C. K., & Horowitz, M. (2013). Effects of Vildagliptin on Glucose, Insulin, Triglyceride, Energy Expenditure and Energy Intake Responses to an Intraduodenal Fat infusion in Healthy Men. In DIABETES Vol. 62 (pp. A497). AMER DIABETES ASSOC. 2013 Trahair, L. G., Marathe, C. S., Lange, K., Rayner, C. K., Horowitz, M., & Jones, K. L. (2013). Relationships of Glycemia With Gastric Emptying of an Oral Glucose Load in Healthy Older Subjects. In DIABETES Vol. 62 (pp. A517). AMER DIABETES ASSOC. 2013 Marathe, C., Rayner, C., Bound, M., Checklin, H., Standfield, S., Jones, K. L., & Horowitz, M. (2013). The Size of the Incretin Effect Is Dependent on the Rate of Small Intestinal Glucose Entry in Type 2 Diabetes. In DIABETES Vol. 62 (pp. A474). AMER DIABETES ASSOC. 2012 Marathe, C. S., Rayner, C. K., Jones, K. L., & Horowitz, M. (2012). The Size of the Incretin Effect is Dependent on the Small Intestinal Glucose Load. In DIABETES Vol. 61 (pp. A94-A95). Philadelphia, PA: AMER DIABETES ASSOC.
WoS12012 Nguyen, Q., Burgstad, C., Debreceni, T., Bellon, M., Wishart, J., Rayner, C., & Horowitz, M. (2012). Whey protein pre-load attenuates post-prandial hyperglycaemia and reduces carbohydrate absorption in patients with Roux-en-Y gastric bypass. In Journal of Gastroenterology and Hepatology Vol. 27 (pp. 139). Australia: Wiley.
DOI2012 Bound, M., Wu, T., Gedulin, B., Horowitz, M., & Rayner, C. (2012). Effects of bile acid enemas on GLP-1 and PYY secretion in healthy humans. In Diabetologia Vol. 55 (pp. S338). Germany: Springer.
DOI2012 Zhao, R., Wu, T., Jones, K., Horowitz, M., & Rayner, C. (2012). Effects of a D-xylose preload, with or without sitagliptin, on gastric emptying and postprandial glycaemia in patients with type 2 diabetes. In Journal of Gastroenterology and Hepatology Vol. 27 (pp. 148-149). Australia: Wiley-Blackwell.
DOI2012 Nguyen, N. Q., Debreceni, T. L., Burgstad, C. M., Wishart, J. M., Bellon, M., Rayner, C., & Horowitz, M. (2012). Effects of Posture and Meal Volume on Pouch Emptying, Intestinal Transit, Blood Glucose, Gut Hormone Concentrations and Gastrointestinal Symptoms in Patients With Gastric Bypass. In GASTROENTEROLOGY Vol. 142 (pp. S560). CA, San Diego: W B SAUNDERS CO-ELSEVIER INC. 2011 Young, R. L., Chia, B., Ma, J., Wu, T., Khoo, J., Horowitz, M., . . . Rayner, C. (2011). Disordered Control of Intestinal Sweet Taste Receptor Expression in Type 2 Diabetes. In GASTROENTEROLOGY Vol. 140 (pp. S99-S100). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC. 2011 Little, T., Young, R., Blackshaw, L., Rayner, C., & Feinle-Bisset, C. (2011). Expression of the fatty acid sensors, CD36, GPR119 and GPR120, in the duodenum of humans. Relationships with obesity. In 19th Annual Meeting of the Society for the Study of Ingestive Behavior Vol. 575 (pp. S26). Netherlands: Elsevier BV.
DOI2011 Wu, T., Zhao, B., Bound, M., Checklin, H. L., Bellon, M., Little, T. J., . . . Rayner, C. K. (2011). Effects of different sweet preloads on incretin hormone responses, gastric emptying and postprandial glycaemia in healthy humans. In DIABETOLOGIA Vol. 54 (pp. S330). Lisbon, PORTUGAL: SPRINGER. 2011 Marathe, C. S., Horowitz, M., Rayner, C. K., Lange, K., & Jones, K. L. (2011). Biphasic relationship between glucose tolerance and gastric emptying in healthy subjects. In DIABETOLOGIA Vol. 54 (pp. S231). Lisbon, PORTUGAL: SPRINGER. 2011 Young, R. L., Deane, A. M., Chia, B., Horowitz, M., Blackshaw, L. A., & Rayner, C. (2011). Dysregulation of Intestinal Glucose Transporter and Sweet Taste Receptor Expression in Critical Illness. In GASTROENTEROLOGY Vol. 140 (pp. S194). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC. 2010 Horowitz, M., Ma, J., Jesudason, D. R., Russo, A., Stevens, J. E., Keogh, J. B., . . . Rayner, C. K. (2010). Sustained effects of a protein 'preload' on gastric emptying and glycaenna in type 2 diabetes over 4 weeks. In DIABETOLOGIA Vol. 53 (pp. 1 page). Stockholm, SWEDEN: SPRINGER. 2010 Wu, T., Zhao, B., Bound, M., Checklin, H. L., Bellon, M., Little, T., . . . Rayner, C. K. (2010). Effects of sweet preloads on gastric emptying and postprandial glycaemia in healthy subjects. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 25 (pp. A105). WILEY-BLACKWELL PUBLISHING, INC. 2010 Ma, J., Wishart, J. M., Jones, K. L., Horowitz, M., & Rayner, C. K. (2010). Dose dependent effects of protein 'preloads' on gastrointestinal hormones, glycaemia, and energy intake in type 2 diabetes. In DIABETOLOGIA Vol. 53 (pp. 1 page). Stockholm, SWEDEN: SPRINGER. 2010 Rayner, C. K., Ma, J., Checklin, H. I., Wishart, J. M., Stevens, J. E., Jones, K. L., . . . Meyer, J. H. (2010). Effects of enterically coated, nutrient-containing pellets on glycaemia and incretin hormone release in patients with type 2 diabetes. In DIABETOLOGIA Vol. 53 (pp. 1 page). Stockholm, SWEDEN: SPRINGER. 2010 Ma, J., Wu, T., Checklin, H. L., Wishart, J. M., Stevens, J., Jones, K. L., . . . Rayner, C. K. (2010). Effects of enterically coated, nutrient-containing pellets on glycaemia and incretin hormone release in type 2 diabetes. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 25 (pp. A114-A115). WILEY-BLACKWELL PUBLISHING, INC. 2010 Gentilcore, D., Vanis, L., Rayner, C. K., Horowitz, M., & Jones, K. L. (2010). Effects Of Intraduodenal Acarbose On Blood Pressure, Heart Rate And Splanchnic Blood Flow In Healthy Older Subjects.. In JOURNAL OF THE AMERICAN GERIATRICS SOCIETY Vol. 58 (pp. 92). Orlando, FL: WILEY-BLACKWELL PUBLISHING, INC.
WoS12009 Rayner, C. K., Ma, J., Pilichiewicz, A., Feinle-Bisset, C., Checklin, H. L., Wishart, J. M., . . . Horowitz, M. (2009). Effects of variations in duodenal glucose load on glycaemia, insulin and GLP-1 in type 2 diabetes. In DIABETOLOGIA Vol. 52 (pp. S105-S106). Vienna, AUSTRIA: SPRINGER.
WoS72009 Ma, J., Stevens, J. E., Cukier, K., Maddox, A. F., Wishart, J. M., Bowen, J., . . . Rayner, C. K. (2009). Effects of protein on gastric emptying and the glycaemic, insulin and gastrointestinal hormone responses to a carbohydrate meal in type 2 diabetes. In DIABETOLOGIA Vol. 52 (pp. S324). Vienna, AUSTRIA: SPRINGER. 2009 Kuo, P., Chaikomin, R., Bellon, M., Horowitz, M., Jones, K. L., & Rayner, C. (2009). Validation of 3-O-(14c) Methylglucose As a Marker of Glucose Absorption. In GASTROENTEROLOGY Vol. 136 (pp. A539-A540). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
WoS12009 Kuo, P., Bellon, M., Smout, A., Holloway, R. H., Fraser, R. J., Horowitz, M., . . . Rayner, C. (2009). Effects of Metoclopramide On Duodenal Motility and Flow Events, and Glucose Absorption, in Healthy Humans. In GASTROENTEROLOGY Vol. 136 (pp. A540). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC. 2009 Kuo, P., Stevens, J. E., Bellon, M., Jones, K. L., Horowitz, M., Greville, H., . . . Rayner, C. (2009). Acute Effects of Pancreatic Enzyme Replacement On Gastric Emptying and Postprandial Glycaemia in Patients with Cystic Fibrosis. In GASTROENTEROLOGY Vol. 136 (pp. A555). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
WoS32009 Kuo, P., Gentilcore, D., Nair, N., Stevens, J. E., Gilja, O. H., Hausken, T., . . . Rayner, C. (2009). Effects of the Nitric Oxide (NO) Synthase Inhibitor, NG-Nitro-L-Arginine-Methyl-Ester (L-NAME), On Delayed Gastric Emptying Induced By Hyperglycaemia in Healthy Humans. In GASTROENTEROLOGY Vol. 136 (pp. A779). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC. 2008 Sutherland, K., Brierley, S. M., Rayner, C., Horowitz, M., Blackshaw, L. A., & Young, R. L. (2008). Altered duodenal sweet taste receptor expression in diabetic hyperglycemia. In GASTROENTEROLOGY Vol. 134 (pp. A44). W B SAUNDERS CO-ELSEVIER INC. 2008 Ma, J., Stevens, J. E., Maddox, A. F., Bowen, J., Jones, K. L., Wishart, J., . . . Rayner, C. (2008). Effect of a protein preload on gastric emptying and glycemia in type 2 diabetes. In GASTROENTEROLOGY Vol. 134 (pp. A247-A248). W B SAUNDERS CO-ELSEVIER INC.
WoS12008 Kuo, P., Bellon, M., Smout, A. J., Holloway, R. H., Fraser, R. J., Horowitz, M., . . . Rayner, C. K. (2008). Effects of metoclopramide on duodenal motility and flow events, and glucose absorption, in healthy humans. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 23 (pp. A289). WILEY-BLACKWELL. 2007 Chaikomin, R., Wu, K. -L., Doran, S., Meyer, J. H., Jones, K. L., Horowitz, M., & Rayner, C. (2007). Effects of MID-jejunal compared to duodenal glucose infusion on gut hormone release and appetite. In GASTROENTEROLOGY Vol. 132 (pp. A545). Washington, DC: W B SAUNDERS CO-ELSEVIER INC. 2007 Kuo, P., Chaikomin, R., Pilichiewicz, A., O'donovan, D. G., Wishart, J., Meyer, J. H., . . . Rayner, C. (2007). Transient, early release of glucagon-like peptide-1 during low rates of intraduodenal glucose delivery. In GASTROENTEROLOGY Vol. 132 (pp. A545). Washington, DC: W B SAUNDERS CO-ELSEVIER INC. 2007 Karamanlis, A., Chaikomin, R., Doran, S., Bellon, M., Bartholomeusz, D., Wishart, J., . . . Rayner, C. (2007). Effects of protein on glycemic and incretin responses, and gastric emptying, after oral glucose in healthy subjects. In GASTROENTEROLOGY Vol. 132 (pp. A544-A545). Washington, DC: W B SAUNDERS CO-ELSEVIER INC. 2007 Sutherland, K., Brierley, S. M., Horowitz, M., Rayner, C., Blackshaw, L. A., & Young, R. L. (2007). Sweet taste transduction molecules are expressed in the upper gastrointestinal tract in humans. In GASTROENTEROLOGY Vol. 132 (pp. A587). Washington, DC: W B SAUNDERS CO-ELSEVIER INC.
WoS32006 Chaikomin, R., Doran, S., Horowitz, M., & Rayner, C. (2006). Effects of intraluminal local anesthetic on duodenal glucose sensing in humans. In GASTROENTEROLOGY Vol. 130 (pp. A251-A252). CA, Los Angeles: W B SAUNDERS CO-ELSEVIER INC. 2006 Wu, K. -L., Chaikomin, R., Doran, S., Jones, K. L., Horowitz, M., & Rayner, C. (2006). Artificially sweetened, compared to regular mixers, accelerate gastric emptying and the rate of alcohol absorption. In GASTROENTEROLOGY Vol. 130 (pp. A433). Los Angeles, CA: W B SAUNDERS CO-ELSEVIER INC. 2006 Stevens, J. E., Russo, A., Maddox, A. F., Rayner, C. K., Phillips, L., Talley, N. J., . . . Jones, K. L. (2006). Effect of itopride hydrochloride on gastric emptying in longstanding diabetes mellitus. In AMERICAN JOURNAL OF GASTROENTEROLOGY Vol. 101 (pp. S89). Las Vegas, NV: LIPPINCOTT WILLIAMS & WILKINS.
DOI2005 Chaikomin, R., Doran, S., Jones, K. L., Feinle-Bisset, C., Wishart, J. M., O'Donovan, D. G., . . . Horowitz, M. (2005). More rapid small intestinal glucose delivery increases plasma insulin, GIP and GLP-1, but does not improve overall glycemia in healthy subjects. In GASTROENTEROLOGY Vol. 128 (pp. A357). Chicago, IL: W B SAUNDERS CO. 2003 Rayner, C. K., Kamm, M. A., Knowles, C. H., Scott, S. M., & Lunniss, P. J. (2003). Idiopathic slow transit constipation: A rarity in males. In GUT Vol. 52 (pp. A84). BIRMINGHAM, ENGLAND: BRITISH MED JOURNAL PUBL GROUP. 2001 Su, Y. C., Vozzo, R., Doran, S., Leelakusolvong, S., Rayner, C. K., Chapman, I. M., . . . Horowitz, M. (2001). Effects of the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on antropyloroduodenal motility and appetite in response to intraduodenal lipid infusion in humans. In GASTROENTEROLOGY Vol. 120 (pp. A289). W B SAUNDERS CO. 2000 Rayner, C. K., Su, Y. C., Doran, S., Jones, K. L., Malbert, C. H., & Horowitz, M. (2000). The stimulation of antral motility by erythromycin is attenuated during hyperglycemia.. In GASTROENTEROLOGY Vol. 118 (pp. A1195). W B SAUNDERS CO-ELSEVIER INC.
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Conference Items
Year Citation 2023 Xie, C., Huang, W., Sun, Y., Horowitz, M., Jones, K., Rayner, C., & Wu, T. (2023). Disparities in blood glucose and incretin responses to intraduodenal glucose infusion in healthy young males and females. Poster session presented at the meeting of DIABETES RESEARCH AND CLINICAL PRACTICE. ELSEVIER IRELAND LTD.
DOI2023 Portmann, L., Bryant, R., Raja, S., Rayner, C., Telfer, K., Costello, S., & Day, A. (2023). Comprehensive dietitian-delivered dietary advice effectively achieves dietary change in adults with ulcerative colitis, whereas generalized written dietary advice does not. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY. 2023 Portmann, L., Bryant, R., Raja, S., Rayner, C., Telfer, K., Costello, S., & Day, A. (2023). Habitual diets of Australian adults with ulcerative colitis are carnivorous and lack fiber: A cross-sectional study. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY. 2023 Veedfald, S., Sun, Y., Xiang, C., Xie, C., Wu, T., Bound, M., . . . Rayner, C. K. (2023). Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 do not account for the entire incretin effect in healthy humans. Poster session presented at the meeting of Abstracts of the 59 th EASD Annual Meeting of the European Association for the Study of Diabetes, as published in Diabetologia. Hamburg, Germany: Springer. 2023 Horowitz, M., Xiang, C., Xie, C., Sun, Y., Jones, K. L., Rayner, C. K., . . . Wu, T. (2023). Gastric emptying is slower in women than men with type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2023 Wu, T., Xie, C., Iroga, P., Bound, M., Grivell, J., Huang, W., . . . Rayner, C. (2023). The impact of timing of metformin administration on glycaemic and glucagon like peptide 1 responses to intraduodenal glucose in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2023 Xiang, C., Sun, Y., Luo, Y., Xie, C., Huang, W., Sun, Z., . . . Wu, T. (2023). Gastric emptying of 75g oral glucose is predictive of the glycaemic response to mixed meals as well as oral glucose, but unrelated to antecedent glycaemia in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2023 Quast, D. R., Lancaster, D., Xie, C., Bound, M. J., Grivell, J., Jones, K. L., . . . Nauck, M. A. (2023). Glucagon-like peptide 1 for lowering plasma glucose in hyperglycaemic subjects with type 2 diabetes: a systematic comparison of intravenous and subcutaneous routes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2023 Huynh, L. Q., Hatzinikolas, S., Jalleh, R. J., Marathe, C. S., Wu, T., Malbert, C. -H., . . . Jones, K. L. (2023). Effect of exenatide once-weekly (QW) on the blood pressure and glycaemic responses to a mashed potato meal in type 2 diabetes: relationships to gastric emptying. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2023 Rayner, C. K., Huang, W., O'Hara, S. E., Xie, C., Nicholas, L. M., & Wu, T. (2023). Effects of a bitter tasting substance, denatonium benzoate, on pancreatic hormone secretion. Poster session presented at the meeting of Abstracts of the 59th Annual Meeting of the European Association for the Study of Diabetes (EASD 2023), as published in Diabetologia. Hamburg, Germany: Springer.
DOI2023 Borg, M. J., Xie, C., Rayner, C., Horowitz, M., Jones, K., & Wu, T. (2023). Fasting plasma GIP is related to metabolic derangements in health and type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2023 Xie, C., Huang, W., Bound, M., Grivell, J., Jones, K., Horowitz, M., . . . Wu, T. (2023). Effect of intestinal exposure to endogenous bile acids on the incretin axis in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2023 Li, T., Sang, M., Wang, J., Sun, Z., Xie, C., Rayner, C., . . . Wu, T. (2023). Tea consumption is associated with increased urinary glucose excretion, improved insulin resistance and reduced risk of dysglycaemia, in Chinese community-dwelling adults. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER. 2022 Xie, C., Jalleh, R. J., Huang, W., Sun, Y., Jones, K. L., Horowitz, M., . . . Wu, T. (2022). Determinants of blood glucose concentrations after a high carbohydrate meal in type 2 diabetes: a multiple linear regression analysis. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm & Online: Springer.
DOI2022 Wu, T., Xie, C., Huang, W., Sun, Y., Horowitz, M., Jones, K. L., & Rayner, C. K. (2022). Disparities in blood glucose and incretin responses to intraduodenal glucose infusion in healthy young males and females. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm, Sweden & Online: Springer.
DOI2022 Huang, W., Xie, C., Albrechtsen, N. J. W., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2022). The 'early' postprandial glucagon response to a mixed meal is dependent on the rate of gastric emptying in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm, Sweden & Online: Springer.
DOI2021 Huang, W., Zhao, J., Nicholas, L. M., Shallan, A., Priest, C., Rayner, C. K., . . . Wu, T. (2021). An integrated microfluidic sensing system platform for dissecting insulin secretion and extracellular Ca²⁺ dynamics of pancreatic islets. Poster session presented at the meeting of Abstracts of the 57th EASD Annual Meeting of the European Association for the Study of Diabetes, as published in Diabetologia. Virtual: Springer.
DOI2020 Kreuch, D., Ivey, K., Mobegi, F. M., Leong, L., Isaacs, N. J., Pezos, N., . . . Young, R. L. (2020). Mechanisms linking low-calorie sweeteners to impaired glycaemic control. Poster session presented at the meeting of Abstracts of the 4th Meeting of the Federation of Neurogastroenterology and Motility (FNM 2020), as published in Neurogastroenterology and Motility. Adelaide Convention Centre, Adelaide, Australia: Wiley.
DOI2020 Wang, X., Chen, C., Xie, C., Horowitz, M., Jones, K. L., Rayner, C. K., . . . Wu, T. (2020). Serum bile acids after an oral glucose load in Chinese healthy individuals and patients with type 2 diabetes: relationships with glycaemia. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER. 2020 Xie, C., Wang, X., Bound, M. J., Young, R. L., Jones, K. L., Horowitz, M., . . . Wu, T. (2020). Bitter taste signalling modulates bile acid-induced PYY, but not GLP-1 secretion in healthy humans. Poster session presented at the meeting of Abstracts of the 56th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Virtual Online: Springer-Verlag.
DOI2020 Wu, T., Xie, C., Wang, X., Bound, M. J., Grivell, J., Jones, K. L., . . . Rayner, C. K. (2020). Role of endogenous glucagon-like peptide-1 in the serum triglyceride response to intraduodenal fat infusion in type 2 diabetic patients on vildagliptin. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER. 2020 Sansome, D. J., Veedfald, S., Xie, C., Bound, M., Grivell, J., Jones, K. L., . . . Wu, T. (2020). Role of bile acids on glucose-lowering by metformin in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER. 2020 Huynh, L. Q., Ng, S., Xie, D., Hargreaves, M., Murthy, T. A., Wu, T., . . . Marathe, C. S. (2020). Diabetes distress is associated with gastrointestinal symptoms in type 1 diabetes. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER. 2020 Bizzotto, R., Rayner, C. K., Watson, L. E., Phillips, L. K., Lange, K., Bound, M. J., . . . Mari, A. (2020). Comparison of paracetamol absorption and gastric emptying measured by scintigraphy in relation to rate of appearance of oral glucose and postprandial glycaemia. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER. 2020 Schubert, J., Gehlert, J., Rayner, C., Roberts-Thomson, I., Costello, S., Mangoni, A., & Bryant, R. (2020). Prevalence of primary and secondary antibiotic resistance of Helicobacter pylori in Australia and New Zealand: A systematic review and meta-analysis. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY. 2020 Schubert, J., Warner, M., Rayner, C., Roberts-Thomson, I., Ngoi, B., Costello, S., & Bryant, R. (2020). Increasing primary antibiotic resistance of Helicobacter pylori in Australia over 20 years. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY. 2019 Ooi, M., Wong, S., Rayner, C., & Nguyen, N. Q. (2019). CHARACTERIZATION AND OUTCOMES OF OESOPHAGEAL MOTILITY DISORDER IN ELDERLY WITH FOOD BOLUS OBSTRUCTION. Poster session presented at the meeting of GASTROINTESTINAL ENDOSCOPY. San Diego, CA: MOSBY-ELSEVIER.
DOI2019 Ooi, M., Wong, S., Rayner, C., Duong, T. A., & Nguyen, N. Q. (2019). SAFETY AND TREATMENT OUTCOMES OF SAME-SESSION ENDOSCOPIC DILATION (SSED) OF THE ESOPHAGUS AFTER REMOVAL OF FOOD BOLUS OBSTRUCTION (FBO): INTERIM ANALYSIS. Poster session presented at the meeting of GASTROINTESTINAL ENDOSCOPY. San Diego, CA: MOSBY-ELSEVIER.
DOI2019 Ooi, M., Wong, S., Duong, T., Appleyard, M., Rayner, C., Grimpen, F., & Nguyen, N. (2019). Luminal Basic Science. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
DOI WoS12019 Jalleh, R. J., Pham, H. T., Marathe, C. S., Wu, T., Buttfield, M. D., Hatzinikolas, S., . . . Jones, K. L. (2019). Acute effects of lixisenatide on intragastric meal distribution: impact on energy intake. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER. 2019 Jones, K. L., Huynh, L. Q., Hatzinikolas, S., Rigda, R. S., Phillips, L., Pham, H. T., . . . Horowitz, M. (2019). Effect of exenatide once-weekly (QW) on gastric emptying in health: impact on glycaemia and glucose absorption. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
WoS12019 Huynh, L. Q., Pham, H. T., Holen, I. S., Hatzinikolas, S., Phillips, L., Wu, T., . . . Jones, K. L. (2019). Effects of a guar/whey preload on gastric emptying and glycaemic responses to oral glucose in healthy older people. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER. 2019 Xie, C., Wang, X., Bound, M. J., Grivell, J., Jones, K. L., Horowitz, M., . . . Wu, T. (2019). Roles of endogenous GLP-1 in the glycaemic and energy expenditure responses to fat in type 2 diabetes studied using vildagliptin and exendin(9-39). Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER. 2019 Marathe, C. S., Rigda, R. S., Buttfield, M., Hatzinikolas, S., Pham, H. T., Wu, T., . . . Jones, K. L. (2019). Acute administration of lixisenatide diminishes the insulin secretory response to oral glucose by slowing gastric emptying. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER. 2019 Marathe, J. A., Pham, H., Trahair, L., Huynh, L. Q., Wu, T., Rayner, C. K., . . . Marathe, C. S. (2019). Relationships between GIP and GLP-1 secretion in people with normal or impaired glucose tolerance. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER. 2019 Horowitz, M., Xie, C., Wang, X., Bound, M. J., Grivell, J., Jones, K. L., . . . Wu, T. (2019). Comparative effects of intraduodenal glucose and fat on blood pressure and heart rate in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 55th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Barcelona, SPAIN: Springer-Verlag.
DOI2019 Murthy, T. A., Grivell, J., Hatzinikolas, S., Weinel, L., Rayner, C., Chapple, L. S., . . . Marathe, C. S. (2019). The magnitude of acceleration of gastric emptying by acute hypoglycaemia in health is dependent on the level of hypoglycaemia. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
WoS12019 Wu, T., Zhang, X., Horowitz, M., Jones, K. L., & Rayner, C. K. (2019). Comparative effects of proximal and distal small intestinal glucose exposure on blood pressure, heart rate and mesenteric blood flow in health and type 2 diabetes. Poster session presented at the meeting of Diabetologia. Barcelona, Spain: Springer. 2018 Wu, T., Borg, M., Jones, K. L., Horowitz, M., & Rayner, C. K. (2018). Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and GLP-1, and gastric emptying after oral glucose in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. Berlin, GERMANY: SPRINGER. 2018 Veedfald, S., Wu, T., Bound, M., Grivell, J., Hartmann, B., Rehfeld, J. F., . . . Rayner, C. K. (2018). Hyperosmolar duodenal saline infusion lowers circulating ghrelin and stimulates intestinal hormone release in young men. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY. 2018 Giezenaar, C., Watson, L., Rayner, C., Horowitz, M., Chapman, I., & Soenen, S. (2018). Ultrasonographic muscle and subcutaneous fat thickness as a measure of body composition and muscle function. Poster session presented at the meeting of AUSTRALASIAN JOURNAL ON AGEING. WILEY. 2018 Xie, C., Wang, X., Bound, M. J., Grivell, J., Young, R. L., Jones, K. L., . . . Wu, T. (2018). Effects of the bitter taste receptor agonist, denatonium benzoate, on postprandial glycaemia, gastric emptying and energy intake in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 54th Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI2018 Jones, K. L., Stevens, J. E., Buttfield, M., Wu, T., Hatzinikolas, S., Pham, H., . . . Horowitz, M. (2018). The reduction in postprandial glucose by sitagliptin is related to the rate of gastric emptying in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. Berlin, GERMANY: SPRINGER. 2018 Young, R. L., Kreuch, D., Mobegi, F. M., Leong, L., Schober, G., Isaacs, N. J., . . . Rogers, G. B. (2018). Low-calorie sweeteners disrupt the gut microbiome in healthy subjects in association with impaired glycaemic control. Poster session presented at the meeting of Abstracts of the 54th Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI2017 Phillips, L., Watson, L., Wu, T., Bound, M., Checklin, H., Grivell, J., . . . Rayner, C. (2017). Longitudinal evaluation of gastric emptying in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI2017 Jones, K., Rigda, R., Buttfield, M., Hatzinikolas, S., Pham, H., Marathe, C., . . . Horowitz, M. (2017). Acute effects of lixisenatide on gastric emptying, glycaemia and 'postprandial' blood pressure responses to an oral glucose load in healthy subjects and type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS12017 Young, R., Isaacs, N., Schober, G., Wu, T., Cvijanovic, N., Pezos, N., . . . Horowitz, M. (2017). Impact of artificial sweeteners on glycaemic control in healthy humans. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS42017 Rayner, C., Wu, T., Horowitz, M., & Jones, K. (2017). Blockade of glucagon-like peptide-1 receptors by exendin(9-39) attenuates the increase in heart rate during small intestinal glucose infusion in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS12017 Wu, T., Horowitz, M., Jones, K., & Rayner, C. (2017). Endogenous glucagon-like peptide-1 mediates the lowering of glycaemia during small intestinal glucose infusion by bile acids in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS22017 Buttfield, M., Stevens, J., Hatzinikolas, S., Wu, T., Pham, H., Lange, K., . . . Jones, K. (2017). EFFECTS OF SITAGLIPTIN ON GASTRIC EMPTYING OF, AND THE BLOOD PRESSURE RESPONSE TO, A CARBOHYDRATE MEAL IN TYPE 2 DIABETES. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY. 2016 Phillips, L. K., Marathe, C., Trahair, L., Bound, M. J., Hatzinikolas, S., Mignone, L. E., . . . Horowitz, M. (2016). Preliminary observations of gastric emptying in diabetic ketoacidosis. Poster session presented at the meeting of DIABETOLOGIA. Munich, GERMANY: SPRINGER. 2016 Zhang, X., Bound, M., Standfield, S., Hu, S., Jones, K., Horowitz, M., . . . Wu, T. (2016). Comparative effects of proximal and distal small intestinal glucose on glycaemia, incretin hormone secretion and incretin effect in healthy males. Poster session presented at the meeting of Abstracts of the 52nd Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Munich, GERMANY: Springer-Verlag.
DOI WoS22016 Wu, T., Zhang, X., Little, T. L., Bound, M. J., Standfield, S., Deacon, C. F., . . . Rayner, C. K. (2016). The rate of intraduodenal glucose delivery affects the lowering of blood glucose by vildagliptin in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. Munich, GERMANY: SPRINGER. 2016 Mignone, L., Wu, T., Phillips, L., Bound, M., Checklin, H., Grivell, J., . . . Rayner, C. (2016). A whey/guar "preload" improves postprandial glycaemia and HbA(1c) in type 2 diabetes: a 12-week, single-blind, randomised and placebo controlled trial. Poster session presented at the meeting of Abstracts of the 52nd Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Munich, GERMANY: Springer-Verlag.
DOI2015 Nguyen, N., Debreceni, T., Burgess, J., Bellon, M., Wishart, J., Standfield, S., . . . Horowitz, M. (2015). Impact of gastric emptying and small intestinal transit on blood glucose, intestinal hormones, glucose absorption in the morbidly obese. Poster session presented at the meeting of Abstract of the Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015. World Congress of Gastroenterology, as published in Journal of Gastroenterology and Hepatology. Brisbane, Queensland: Wiley-Blackwell.
DOI2015 Nguyen, N. Q., Burgess, J. E., Debrecini, T. L., Wishart, J., Rayner, C. K., Horowitz, M., & Young, R. L. (2015). Impact of a 2-week very low calorie diet (vlcd) on fatty acid sensing and transport, incretin hormones and lipid profile in morbidly obese humans. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY-BLACKWELL. 2015 Marathe, C. S., Rayner, C. K., Bound, M., Checklin, H., Standfield, S., Wishart, J., . . . Horowitz, M. (2015). SMALL INTESTINAL GLUCOSE EXPOSURE DETERMINES THE MAGNITUDE OF THE INCRETIN EFFECT IN HEALTH AND TYPE 2 DIABETES. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY-BLACKWELL.
DOI2014 Rigda, R. S., Little, T. J., Trahair, L. G., Lange, K., Feinle-Bisset, C., Rayner, C. K., . . . Jones, K. L. (2014). Effects of region of small intestine exposed to glucose on incretin hormones, insulinaemia and glycaemia in healthy older subjects. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER. 2014 Mignone, L. E., Wu, T., Bound, M. J., Jones, K. L., Horowitz, M., & Rayner, C. K. (2014). A low-dose whey protein preload slows gastric emptying and improves post-prandial glycaemia in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER. 2014 Wu, T., Bound, M., Deacon, C., Jones, K., Horowitz, M., & Rayner, C. (2014). Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity?. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER. 2014 Trahair, L. G., Horowitz, M., Hausken, T., Feinle-Bisset, C., Rayner, C. K., & Jones, K. L. (2014). Effects of exogenous glucagon-like peptide-1 on the blood pressure, heart rate, mesenteric blood low and glycaemic responses to intraduodenal glucose in older subjects. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER. 2013 Thazhath, S. S., Bound, M., Jones, K., Horowitz, M., & Rayner, C. (2013). Effect of hydroxycitric acid on the glycaemic response to a small intestinal glucose load in healthy humans. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY-BLACKWELL. 2012 Wu, T., Zhao, B. R., Horowitz, M., Jones, K. L., & Rayner, C. K. (2012). Effects of a xylose preload, with or without sitagliptin, on gastric emptying and postprandial glycaemia in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER. 2012 Little, T., Ott, R., Young, R., Isaacs, N., Rayner, C., Horowitz, M., & Feinle-Bisset, C. (2012). Expression of duodenal fatty acid receptors in humans is inversely related to body mass index. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY-BLACKWELL. 2012 Young, R., Chia, B., Wu, T., Michael, H., & Rayner, C. (2012). Loss of intestinal sweet taste receptor control in type 2 diabetes: A risk factor for postprandial hyperglycemia?. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY-BLACKWELL. 2010 Young, R., Sutherland, K., Pezos, N., Brierley, S., Ma, J., Rayner, C., . . . Blackshaw, L. (2010). Control of intestinal sweet taste receptor expression is impaired in type 2 diabetes. Poster session presented at the meeting of Proceedings of 2010 Joint International Neurogastroenterology and Motility Meeting (NGM), as published in Neurogastroenterology & Motility. Boston, MA, USA: Wiley-Blackwell Publishing.
DOI WoS22008 Kuo, P., Gentilcore, D., Nair, N., Stevens, J. E., Hausken, T., Horowitz, M., . . . Rayner, C. K. (2008). Effects of the nitric oxide (NO) synthase inhibitor, ng-nitro-l-arginine-methyl-ester (L-NAME), on delayed gastric emptying induced by hyperglycaemia in healthy humans. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY-BLACKWELL PUBLISHING, INC. 2008 Kuo, P., Stevens, J. E., Bellon, M., Jones, K. L., Horowitz, M., Greville, H. W., . . . Rayner, C. K. (2008). Acute effects of pancreatic enzyme replacement on gastric emptying and postprandial glycemia in patients with cystic fibrosis. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY-BLACKWELL. 1998 Andrews, J. M., Rayner, C. K., Doran, S. M., & Horowitz, M. (1998). Variations of blood glucose in the physiological range alter appetite, gastrointestinal sensation, and pyloric motility. Poster session presented at the meeting of Abstracts of the American Gastroenterological Association and Digestive Disease Week (DDW 1998) as published in Gastroenterology. New Orleans, Louisiana: Elsevier.
DOI1998 Verhaaen, M. A. M. T., Rayner, C. K., Andrews, J. M., Doran, S. M., Hebbard, G. S., Samsom, M., & Horowitz, M. (1998). Effect of physiological changes in blood glucose on proximal gastric motor and sensory function. Poster session presented at the meeting of Abstracts of the Netherlands Society of Gastroenterology and the Netherlands Society of Hepatology: Spring Meeting, 19–20 March 1998. Lippincott Williams.
DOI -
Preprint
Year Citation 2023 Ow, T. -W., Sukocheva, O., Bampton, P., Iyngkaran, G., Rayner, C. K., & Tse, E. (2023). Improving Concordance Between Clinicians With Australian Guidelines for Bowel Cancer Prevention Using a Digital Application: Randomized Controlled Crossover Study (Preprint).
DOI2023 Zhou, X., Wu, T., Sang, M., Qiu, S., Wang, B., Guo, H., . . . Sun, Z. (2023). Variations in Blood Pressure Before and after 75 g Oral Glucose in Chinese Community-Dwelling Adults: Implications for the Detection of Both Hypertension and Postprandial Hypotension.
DOI
Research Funding Support
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 Principal Supervisor Faecal Microbiota Transplant (FMT) as a safe and efficacious therapeutic alternative for refractory proctitis Doctor of Philosophy Doctorate Full Time Dr Sreecanth Raja 2023 Co-Supervisor The impact of obesity and adiposity on inflammatory bowel disease Master of Clinical Science Master Part Time Dr Patricia Kaazan 2022 Co-Supervisor Joint Award Project: Bile Acids and Glycaemia Control in Health and Type 2 Diabetes Doctor of Philosophy under a Jointly-awarded Degree Agreement with Doctorate Full Time Miss Yixuan Sun 2021 Co-Supervisor Critical care nutrition throughout the hospital continuum Doctor of Philosophy Doctorate Full Time Miss Elizabeth Viner Smith 2021 Principal Supervisor Brachy therapy with intra-tumor injection of OncoSil (phosphorus-32) in pancreatic tumors Doctor of Philosophy Doctorate Full Time Miss Amanda Huoy Wen Lim 2019 Principal Supervisor Improving Digestive Health Using Novel Electronic Models of Care Doctor of Philosophy Doctorate Full Time Tsai-Wing Ow -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2021 - 2024 Principal Supervisor Improving treatment outcomes and prognosticating gastric cancer risk in patients with Helicobacter pylori infection Doctor of Philosophy Doctorate Full Time Mr Jonathon Paul Schubert 2019 - 2023 Co-Supervisor Understanding intestinal and pancreatic hormone secretion in health and type 2 diabetes: (pre-)clinical studies and technical innovations Doctor of Philosophy Doctorate Full Time Dr Weikun Huang 2017 - 2021 Principal Supervisor The role of gastrointestinal function in the regulation of postprandial glycaemia and energy balance in health and type 2 diabetes Doctor of Philosophy Doctorate Full Time Mr Cong Xie 2015 - 2018 Principal Supervisor A Novel Nutritional Approach to the Management of Type 2 Diabetes: Effects of Nutritional Preloads on Postprandial Blood Glucose and Gastric Emptying in Type 2 Diabetes Mellitus Doctor of Philosophy Doctorate Full Time Dr Linda Ernestine Watson 2015 - 2022 Co-Supervisor Targeting Postprandial Hyperglycaemia with Exenatide in Young People with Cystic Fibrosis Master of Philosophy (Medical Science) Master Part Time Ms Myfanwy Geyer 2014 - 2015 Co-Supervisor Gastric emptying and its relationship with postprandial glycaemic control in young people with cystic fibrosis and type 1 diabetes Master of Philosophy (Medical Science) Master Full Time Mrs Shiree Perano 2013 - 2016 Principal Supervisor Gastrointestinal Mediation of Glucose Homeostasis and Postprandial Cardiovascular Risk Doctor of Philosophy Doctorate Full Time Dr Sony Thazhath 2012 - 2016 Co-Supervisor Relationships of Gastric Emptying with Glycaemia. Insulin Secretion and the Incretin Effect in Health and Type 2 Diabetes Doctor of Philosophy Doctorate Part Time Dr Chinmay Marathe 2010 - 2012 Co-Supervisor Gastric Motor Function in Health and Diabetes - Implications for Incretin Hormone Release and Postprandial Blood Glucose Regulation Master of Philosophy (Medical Science) Master Full Time Dr Jessica Lee Sing Chang 2009 - 2013 Principal Supervisor Gastrointestinal motor and sensory function and hormone secretion - implications for postprandial blood glucose regulation in type 2 diabetes mellitus Doctor of Philosophy Doctorate Full Time APrf Tongzhi Wu 2007 - 2011 Co-Supervisor The role of gastric and small intestinal mechanisms in postprandial hypotension Doctor of Philosophy Doctorate Full Time Ms Lora Vanis 2006 - 2010 Principal Supervisor Gastrointestinal motor function and glycaemic control in diabetes Doctor of Philosophy Doctorate Full Time Mrs Jing Ma 2006 - 2010 Principal Supervisor Gastric and Small Intestinal Motor Function in Health and Disease - Implications for Glucose Absorption, Incretin Hormone Release, and Postprandial Blood Glucose Regulation Doctor of Philosophy Doctorate Full Time Mr Paul Kuo 2004 - 2007 Co-Supervisor Gastrointestinal Motility and Glycaemic Control in Diabetes Doctor of Philosophy Doctorate Full Time Ms Reawika Chaikomin
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Committee Memberships
Date Role Committee Institution Country 2021 - ongoing Member Grants Advisory Committee Royal Australiasian College of Physicians Australia 2021 - ongoing Member Gastrointestinal Expert Group Therapeutic Guidelines Australia 2019 - ongoing - Medical Programs Oversight and Operations Committee University of Adelaide Australia 2016 - ongoing Member RAH Research Committee Scholarship and Fellowship Panel Royal Adelaide Hospital Australia 2009 - 2016 - School of Medicine Research Committee University of Adelaide Australia 2005 - 2016 - Year 1 MBBS Course Committee University of Adelaide Australia 2004 - ongoing - Medical Education Committee Royal Adelaide Hospital Australia -
Memberships
Date Role Membership Country 2013 - ongoing Member American Diabetes Association United States 2009 - ongoing Member European Association for the Study of Diabetes - 2006 - ongoing Member American Gastroenterological Association United States 2004 - ongoing Member Gastroenterological Society of Australia Australia 1992 - ongoing Member Australian Medical Association Australia -
Offices Held
Date Office Name Institution Country 2019 - ongoing Chair, BMD Research Development Group University of Adelaide Australia 2008 - ongoing Regional Examiner, Royal Adelaide Hospital Royal Australasian College of Physicians Australia 2005 - ongoing Honours Program Coordinator, School of Medicine University of Adelaide Australia
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