Associate Professor Tak Kee

Tak Kee
Associate Professor
School of Physical Sciences
Faculty of Sciences

My group uses steady state and time-resolved spectroscopic techniques to investigate the molecular processes in two significant systems. The first system is the important medicinal pigment curcumin. We aim to provide molecular insight into the medicinal effects of curcumin, focusing on the role of excited state photophysical processes and metal chelation. In addition, we use molecular assemblies including cyclodextrins and hydrogels to capture and stabilize curcumin in aqueous environment. We use these molecular assemblies to deliver curcumin to cancer cells. Recently, we began to use polymer nanoparticles to capture curcumin with the aim to develop a new means of delivery. Another system of interest is the highly fluorescent conjugated polymer nanostructures. We currently focus on using femtosecond transient absorption spectroscopy and fluorescence upconversion spectroscopy to understand the effect of the shape of the nanostructure on the energy and charge transfer processes in these structures. Because conjugated polymers are used as organic solar cell materials, a good understanding of these processes will lead to strategies for improving the efficiency of organic solar cells.

Connect With Me

Associate Professor Tak Kee

My group uses steady state and time-resolved spectroscopic techniques to investigate the molecular processes in two significant systems. The first system is the important medicinal pigment curcumin. We aim to provide molecular insight into the medicinal effects of curcumin, focusing on the role of excited state photophysical processes and metal chelation. In addition, we use molecular assemblies including cyclodextrins and hydrogels to capture and stabilize curcumin in aqueous environment. We use these molecular assemblies to deliver curcumin to cancer cells. Recently, we began to use polymer nanoparticles to capture curcumin with the aim to develop a new means of delivery. Another system of interest is the highly fluorescent conjugated polymer nanostructures. We currently focus on using femtosecond transient absorption spectroscopy and fluorescence upconversion spectroscopy to understand the effect of the shape of the nanostructure on the energy and charge transfer processes in these structures. Because conjugated polymers are used as organic solar cell materials, a good understanding of these processes will lead to strategies for improving the efficiency of organic solar cells.

My group uses steady state and time-resolved spectroscopic techniques to investigate molecular processes involving light harvesting and energy conversion. A system of interest is the highly fluorescent conjugated polymer nanostructures. We currently focus on using femtosecond transient absorption spectroscopy and fluorescence upconversion spectroscopy to understand the effect of the shape of the nanostructure on the energy and charge transfer processes in these structures. Because conjugated polymers are used as organic solar cell materials, a good understanding of these processes is useful for understanding the limiting factors in the efficiency of organic solar cells.  We have also made progress in stabilizing the highly fluorescent conjugated polymer nanoparticles in high ionic strength condition, facilitating the cell imaging applications of these materials.  This work has also led to progress in fabricating organic light emitting diodes using an aqueous dispersion of conjugated polymers.

Appointments

Date Position Institution name
2015 Associate Professor University of Adelaide
2011 - 2014 Senior Lecturer University of Adelaide
2006 - 2010 Lecturer University of Adelaide
2003 - 2006 Postdoctoral Fellow National Institute of Standards and Technology

Education

Date Institution name Country Title
1999 - 2003 University of Texas at Austin United States PhD
1994 - 1997 Iowa State University United States BSc

Journals

Date Citation
2017 Yang,J, Wen,X, Xia,H, Sheng,R, Ma,Q, Kim,J, Tapping,P, Harada,T, Kee,T, Huang,F et al, 2017, Acoustic-optical phonon up-conversion and hot-phonon bottleneck in lead-halide perovskites, Nature Communications, 8, 1-9 10.1038/ncomms14120
2017 Chung,S, Wen,X, Huang,S, Gupta,N, Conibeer,G, Shrestha,S, Harada,T, Kee,T, 2017, Nanosecond long excited state lifetimes observed in hafnium nitride, Solar Energy Materials and Solar Cells, 169, 13-18 10.1016/j.solmat.2017.04.037
2016 Yan,L, Cui,X, Harada,T, Lincoln,S, Dai,S, Kee,T, 2016, Generation of fluorescent and stable conjugated polymer nanoparticles with hydrophobically modified poly(acrylate)s, Macromolecules, 49, 22, 8530-8539 10.1021/acs.macromol.6b02002
2016 Deng,X, Wen,X, Huang,S, Sheng,R, Harada,T, Kee,T, Green,M, Ho-Baillie,A, 2016, Ultrafast carrier dynamics in methylammonium lead bromide perovskite, Journal of Physical Chemistry C, 120, 5, 2542-2547 10.1021/acs.jpcc.5b11640
2016 Shrestha,A, Jin,B, Kee,T, Qiao,S, Dai,S, 2016, A robust strategy for "living" growth of lead sulfide quantum dots, ChemNanoMat, 2, 1, 49-53 10.1002/cnma.201500110
2016 Zhou,S, Valchev,D, Dinovitser,A, Chappell,J, Iqbal,A, Ng,B-H, Kee,T, Abbott,D, 2016, Terahertz signal classification based on geometric algebra, IEEE Transactions on Terahertz Science & Technology, 6, 6, 793-802 10.1109/TTHZ.2016.2610759
2016 Harada,T, Lincoln,S, Kee,T, 2016, Excited-state dynamics of the medicinal pigment curcumin in a hydrogel, Physical Chemistry Chemical Physics, 18, 40, 28125-28133 10.1039/c6cp05648b
2016 Lin,S, Feng,Y, Wen,X, Harada,T, Kee,TW, Huang,S, Shrestha,S, Conibeer,G, 2016, Observation of hot carriers existing in Ag2S nanoparticles and its implication on solar cell application, Journal of Physical Chemistry C, 120, 19, 10199-10205 10.1021/acs.jpcc.6b02607
2015 Leung,M, Harada,T, Dai,S, Kee,T, 2015, Nanoprecipitation and spectroscopic characterization of curcumin-encapsulated polyester nanoparticles, Langmuir, 31, 42, 11419-11427 10.1021/acs.langmuir.5b02773
2015 Tapping,PC, Clafton,SN, Schwarz,KN, Kee,TW, Huang,DM, 2015, Molecular-level details of morphology-dependent exciton migration in poly(3-hexylthiophene) nanostructures, Journal of Physical Chemistry C, 119, 13, 7047-7059 10.1021/acs.jpcc.5b00705
2015 Harada,T, McTernan,H, Pham,D, Lincoln,S, Kee,T, 2015, Femtosecond transient absorption spectroscopy of the medicinal agent curcumin in diamide linked γ-cyclodextrin dimers, The journal of physical chemistry B, 119, 6, 2425-2433 10.1021/jp507272f
2014 Kee,T, 2014, Femtosecond pump-push-probe and pump-dump-probe spectroscopy of conjugated polymers: new insight and opportunities, Journal of Physical Chemistry Letters, 5, 18, 3231-3240 10.1021/jz501549h
2014 Song,Y, Clafton,S, Pensack,R, Kee,T, Scholes,G, 2014, Vibrational coherence probes the mechanism of ultrafast electron transfer in polymer-fullerene blends, Nature Communications, 5, 4933-1-4933-7 10.1038/ncomms5933
2014 Harada,T, Pham,D-T, Lincoln,S, Kee,T, 2014, The capture and stabilization of curcumin using hydrophobically modified polyacrylate aggregates and hydrogels, The Journal of Physical Chemistry B, 118, 31, 9515-9523 10.1021/jp5060205
2014 Tapping,P, Kee,T, 2014, Optical pumping of poly(3-hexylthiophene) singlet excitons induces charge carrier generation, Journal of Physical Chemistry Letters, 5, 6, 1040-1047 10.1021/jz500217f
2013 Harada,T, Giorgio,L, Harris,T, Pham,D, Ngo,H, Need,E, Coventry,B, Lincoln,S, Easton,C, Buchanan,G et al, 2013, Diamide linked γ-cyclodextrin dimers as molecular-scale delivery systems for the medicinal pigment curcumin to prostate cancer cells, Molecular Pharmaceutics, 10, 12, 4481-4490 10.1021/mp400309s
2013 Schwarz,K, Kee,T, Huang,D, 2013, Coarse-grained simulations of the solution-phase self-assembly of poly(3-hexylthiophene) nanostructures, Nanoscale, 5, 5, 2017-2027 10.1039/c3nr33324h
2013 Clafton,S, Huang,D, Massey,W, Kee,T, 2013, Femtosecond dynamics of excitons and hole-polarons in composite P3HT/PCBM nanoparticles, Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 117, 16, 4626-4633 10.1021/jp308876z
2013 Leung,M, Harada,T, Kee,T, 2013, Delivery of curcumin and medicinal effects of the copper(II)-curcumin complexes, Current Pharmaceutical Design, 19, 11, 2070-2083 10.2174/1381612811319110008
2013 Wallace,S, Kee,T, Huang,D, 2013, Molecular basis of binding and stability of curcumin in diamide-linked y-cyclodextrin dimers, Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 117, 41, 12375-12382 10.1021/jp406125x
2012 Chiu,M, Kee,T, Huang,D, 2012, Coarse-grained simulations of the effects of chain length, solvent quality, and chemical defects on the solution-phase morphology of MEH-PPV conjugated polymers, Australian Journal of Chemistry, 65, 5, 463-471 10.1071/CH12029
2012 Leung,H, Mohan,P, Pukala,T, Scanlon,D, Lincoln,S, Kee,T, 2012, Reduction of Copper(II) to Copper(I) in the Copper-Curcumin Complex Induces Decomposition of Curcumin, Australian Journal of Chemistry, 65, 5, 490-495 10.1071/CH12081
2012 Leung,H, Pham,D, Lincoln,S, Kee,T, 2012, Femtosecond transient absorption spectroscopy of copper(II)–curcumin complexes, Physical Chemistry Chemical Physics, 14, 39, 13580-13587 10.1039/c2cp40208d
2011 Wang,J, Pham,DT, Kee,T, Clafton,S, Guo,X, Clements,P, Lincoln,S, Prud'homme,R, Easton,C, 2011, Aggregation and host-guest interactions in dansyl-substituted poly(acrylate)s in the presence of β-cyclodextrin and a β-cyclodextrin dimer in aqueous solution: a UV-vis, fluorescence, ¹H NMR, and rheological study, Macromolecules, 44, 24, 9782-9791 10.1021/ma202055a
2011 Kee,T, Adhikary,R, Carlson,P, Mukherjee,P, Petrich,J, 2011, Femtosecond fluorescence upconversion investigations on the excited-state photophysics of curcumin, Australian Journal of Chemistry, 64, 1, 23-30 10.1071/CH10417
2011 Harada,T, Pham,D, Leung,H, Ngo,H, Lincoln,S, Easton,C, Kee,T, 2011, Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-Cyclodextrin Dimers: a spectroscopic characterization, Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 115, 5, 1268-1274 10.1021/jp1096025
2011 Addicoat,M, Metha,G, Kee,T, 2011, Density functional theory investigation of Cu(I)- and Cu(II)-curcumin complexes, Journal of Computational Chemistry, 32, 3, 429-438 10.1002/jcc.21631
2011 Adhikary,R, Barnes,C, Trampel,R, Wallace,S, Kee,T, Petrich,J, 2011, Photoinduced trans-to-cis isomerization of cyclocurcumin, Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 115, 36, 10707-10714 10.1021/jp200080s
2010 Pham,DT, Wang,J, Kee,T, Guo,X, Clements,P, Lincoln,S, Prud'homme,R, 2010, Dansyl substituted poly(acrylate)s: Synthesis, host-guest complexation, and viscosity study at molecular and macroscopic levels, PMSE Preprints, 51, 2, 1-2
2010 Wang,Z, Leung,H, Kee,T, English,D, 2010, The role of charge in the surfactant-assisted stabilization of the natural product curcumin, Langmuir, 26, 8, 5520-5526 10.1021/la903772e
2010 Adhikary,R, Carlson,P, Kee,T, Petrich,J, 2010, Excited-state intramolecular hydrogen atom transfer of curcumin in surfactant micelles, Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 114, 8, 2997-3004 10.1021/jp9101527
2010 Clafton,S, Beattie,D, Mierczynska-Vasilev,A, Acres,R, Morgan,A, Kee,T, 2010, Chemical defects in the highly fluorescent conjugated polymer dots, Langmuir, 26, 23, 17785-17789 10.1021/la103063p
2009 Hudson,S, Ecroyd,H, Kee,T, Carver,J, 2009, The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds, FEBS Journal, 276, 20, 5960-5972 10.1111/j.1742-4658.2009.07307.x
2009 Adhikary,R, Mukherjee,P, Kee,T, Petrich,J, 2009, Excited-State Intramolecular Hydrogen Atom Transfer and Solvation Dynamics of the Medicinal Pigment Curcumin, Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 113, 15, 5255-5261 10.1021/jp901234z
2009 Leung,H, Kee,T, 2009, Effective stabilization of curcumin by association to plasma proteins: Human serum albumin and fibrinogen, Langmuir, 25, 10, 5773-5777 10.1021/la804215v
2008 Wallace,S, Morrison,J, Botting,K, Kee,T, 2008, Second-harmonic generation and two-photon-excited autofluorescence microscopy of cardiomyocytes: quantification of cell volume and myosin filaments, Journal of Biomedical Optics, 13, 6, 1-1 10.1117/1.3027970
2008 Leung,H, Colangelo,H, Kee,T, 2008, Encapsulation of curcumin in cationic micelles suppresses alkaline hydrolysis, Langmuir, 24, 11, 5672-5675 10.1021/la800780w
2006 Cicerone,MT, Kee,TW, 2006, PHYS 505-Towards non-invasive, high-resolution hyperspectral imaging of cells and tissues, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 232, -
2006 Kee,T, Zhao,H, Cicerone,M, 2006, One-laser interferometric broadband coherent anti-Stokes Raman scattering, Optics Express, 14, 8, 3631-3640 10.1364/OE.14.003631
2005 Zhang,T, Lee,Y, Kee,T, Barbara,P, 2005, The mechanism of electron-cation geminate recombination in liquid isooctane, Chemical Physics Letters, 403, 4-6, 257-261 10.1016/j.cplett.2005.01.015
2004 Lee,Y, Kee,T, Zhang,T, Barbara,P, 2004, Pump-Probe Spectroscopy of the Hydrated Electron in Reverse Micelles, Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 108, 11, 3474-3478 10.1021/jp0373393
2004 Kee,T, Cicerone,M, 2004, Simple approach to one-laser, broadband coherent anti-Stokes Raman scattering microscopy, Optics Letters, 29, 23, 2701-2703 10.1364/OL.29.002701
2002 Son,D, Kambhampati,P, Kee,T, Barbara,P, 2002, Femtosecond multicolor pump-probe study of ultrafast electron transfer of [(NH₃)₅RuIIINCRuII(CN)₅]⁻ in aqueous solution, Journal of Physical Chemistry A, 106, 18, 4591-4597 10.1021/jp014151f
2002 Kambhampati,P, Son,D, Kee,T, Barbara,P, 2002, Solvation Dynamics of the Hydrated Electron Depends on Its Initial Degree of Electron Delocalization, Journal of Physical Chemistry A, 106, 10, 2374-2378 10.1021/jp014291p
2001 Son,D, Kambhampati,P, Kee,T, Barbara,P, 2001, One-photon UV detrapping of the hydrated electron, Chemical Physics Letters, 342, 5-6, 571-577 10.1016/S0009-2614(01)00167-1
2001 Kee,T, Son,D, Kambhampati,P, Barbara,P, 2001, A unified electron transfer model for the different precursors and excited states of the hydrated electron, Journal of Physical Chemistry A, 105, 37, 8434-8439 10.1021/jp004516g
2001 Son,D, Kambhampati,P, Kee,T, Barbara,P, 2001, Delocalizing Electrons in Water with Light, Journal of Physical Chemistry A, 105, 36, 8269-8272 10.1021/jp012431p
2000 Kambhampati,P, Son,D, Kee,T, Barbara,P, 2000, Solvent Effects on Vibrational Coherence and Ultrafast Reaction Dynamics in the Multicolor Pump-Probe Spectroscopy of Intervalence Electron Transfer, Journal of Physical Chemistry A, 104, 46, 10637-10644 10.1021/jp002549q

Conference Papers

Date Citation
2016 Zhou,S, Valchev,D, Dinovitser,A, Chappell,J, Iqbal,A, Ng,B, Kee,T, Abbot,D, 2016, Dispersion-independent terahertz classification based on Geometric Algebra for substance detection, 41st International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), Copenhagen, DENMARK 10.1109/IRMMW-THz.2016.7758626
2015 Deng,X, Wen,X, Sheng,R, Huang,S, Harada,T, Kee,TW, Green,MA, Ho-Baillie,A, 2015, Ultrafast charge generation and relaxation dynamics in methylammonium lead bromide perovskites, SPIE Conference on Micro+Nano Materials, Devices, and Systems, Sydney, AUSTRALIA 10.1117/12.2202330
2015 Wen,X, Chung,S, Gupta,N, Xia,H, Feng,Y, Shrestha,S, Huang,S, Kee,T, Harad,T, Conibeer,G et al, 2015, Ultrafast transient absorption study of hot carrier dynamics in hafnium nitride and zirconium nitride, IEEE 42nd Photovoltaic Specialist Conference (PVSC), New Orleans, LA 10.1109/PVSC.2015.7356012
2011 Clafton,SN, Kee,TW, 2011, Ultrafast exciton dynamics of conjugated polymer nanoparticles, 242nd National Meeting of the American-Chemical-Society (ACS), Denver, CO
2009 Kee,TW, 2009, COLL 403-Photo-induced unfolding of MEH-PPV nanoparticles
2008 Kee,T, Zhao,H, Cicerone,M, 2008, Elimination of Non-Resonant Background in CARS Imaging using Interferometry [124], Microscopy and Microanalysis, Perth
2008 Wallace,S, Botting,K, Morrison,J, Kee,T, 2008, Quantifcation of Cell Volume of Cardiomyocytes using Second Harmonic Generation and Two Photon Excitation Fluorescence Microscopy, Microscopy and Microanalysis, Perth
2005 Kee,TW, Cicerone,MT, 2005, Biological imaging using broadband Coherent anti-Stokes Raman Scattering (CARS) microscopy, 49th Annual Meeting of the Biopysical-Society, Long Beach, CA
2005 Kee,TW, Becker,ML, Zhao,HX, Kohn,J, Cicerone,MT, 2005, Broadband CARS microscopy as a tool for probing protein adsorption on biocompatible surfaces, 230th National Meeting of the American-Chemical-Society, Washington, DC
2004 Cicerone,MT, Kee,TW, 2004, Broadband CARS imaging of single cells., 228th National Meeting of the American-Chemical-Society, Philadelphia, PA
Year(s) Funding Agency Scheme Grant Title Investigators Amount
2016-2018 Australian Research Council (ARC) Discovery Projects Quantum Coherences in Artificial Light-Harvesting Complexes TW Kee, GD Scholes  
2013 Australian Research Council (ARC) LIEF Supercontinuum Fibre Laser Consortium for the Chemical and Materials Sciences TW Kee, EJ Bieske, GF Metha, TA Smith, PR Medwell, KP Ghiggino  
2010 Australian Research Council (ARC) LIEF Spectroscopic Imaging for Materials, Minerals, and Life Sciences D Beattie, J Ralston, A Ellis, T Kee, K Bremmell, J Morrison, G Andersson, D Lewis, D Saint, K Vasilev, F Malherbe  

2010

Australian Research Council (ARC) LIEF Ultrafast Dynamics Measurement Facility for the Physical, Biomedical and Materials Sciences TW Kee, TM Monro, D Abbott, BM Fischer, GF Metha, JA Carver, DA Beattie, CA Prestidge, RA Lewis, DG Lancaster, U Bach  
Position
Associate Professor
Phone
83135039
Fax
8313 4380
Campus
North Terrace
Building
Badger
Room Number
2 30
Org Unit
Chemistry

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