Dr Scott Clark
Scott a Clinical Academic for the University of Adelaide Discipline of Psychiatry based in the Central Local Health Network and works as a consultant psychiatrist in the Western Community Mental Health Service.
He is the Chair of the metropolitan Adelaide Clozapine Working Group responsible for quality interventions in clozapine care systems. Scott completed a BSc in Psychology at Flinders University in 1994, followed by an Honours in Medical Science at the Centre for Neuroscience at Flinders University in 1995. He went on to study medicine in Adelaide completing his MBBS in 2004, and followed with a PhD in Health Informatics at Adelaide University during which he was supported by a NHMRC Dora Lush Postgraduate Scholarship. His PhD thesis focussed on the development of computer-based alerting systems designed to improve the quality of health care.
Investigator, cognitive function and mood disorders (CoFaMS) and Cognitive and
Functional Assessment of Psychosis Staging Study (CoFAPSS) studies, with an emphasis on recruitment and assessment of patients with chronic psychosis (CoFAPPs) and lithium treated patients (CoFaMS, ConLiGen international consortium); Predictive modeling of symptom and function trajectories in mental illness (transition to first psychotic episode, treatment resistant psychosis); Pharmacogenetics and prediction of response to lithium and clozapine. Health service data linkage studies of patients with chronic psychosis; investigator in the recently established Adelaide Integrated Mental Health Biobank and Disease Marker Centre.
Investigator, cognitive function and mood disorders (CoFaMS) and Cognitive and Functional Assessment of Psychosis Staging Study (CoFAPSS) studies, with an emphasis on recruitment and assessment of patients with chronic psychosis (CoFAPPs) and lithium treated patients (CoFaMS, ConLiGen international consortium); Predictive modeling of symptom and function trajectories in mental illness (transition to first psychotic episode, treatment resistant psychosis); Pharmacogenetics and prediction of response to lithium and clozapine. Health service data linkage studies of patients with chronic psychosis; investigator in the recently established Adelaide Integrated Mental Health Biobank and Disease Marker Centre.
|2014||Consultant psychiatrist||Health SA|
|2013||Clinical Academic||University of Adelaide|
|2017||Award||2017 RANZCP Early Career Psychiatrist Research Award||Royal Australia & New Zealand College of Psychiatry||$10000|
|2015 - 2015||Research Award||Young Investigator Travel Award for the 15th International Congress on Schizophrenia Research||University of Texas||$US 2000|
|2014 - 2014||Nomination||2013 The National Lead Clinicians Group (LCG) Awards for Excellence in Innovative Implementation of Clinical Guidelines – Invited poster on State-wide Clozapine Monitoring Systems||SA Health||Travel reimbursed|
|2013||Teaching Award||Professor Derek Frewin Citation for Clinical Teaching 2013|
|2012||Teaching Award||Professor Derek Frewin Citation for Clinical Teaching 2012||University of Adelaide|
|2011||Award||SA Health Improving Patient Safety Award 2011||SA Health|
|2002 - 2004||Scholarship||Australian National Health and Medical Research Council (NHMRC) Dora Lush Biomedical Scholarship.||University of Adelaide, Department of Medicine, Health Informatics Unit|
|1996||Scholarship||APA PhD Scholarship 1996||Flinders University|
|1994||Award||Shell Prize for 3rd Year Psychology||Flinders University|
|1994||Recognition||Flinders University Chancellor's Letter of Commendation - 1994||Flinders University|
|1993||Recognition||Flinders University Chancellors Letter of Commendation - 1993.||Flinders University|
|1992||Recognition||Flinders University Chancellor's letter of commendation - 1992||Flinders University|
|2009||University of Adelaide||Australia||PhD Medicine (Health Informatics)|
|2004||University of Adelaide||Australia||MBBS|
|1995 - 1995||Flinders University||Australia||Honours Medical Science (Neuroscience)|
|1994 - 1994||Flinders University||Australia||BSc Psychology|
|2008 - 2013||Psychiatry Registrar||Royal Australian and New Zealand College of Psychiatrists||Australia|
|2013||Fellow||Royal Australian and New Zealand College of Psychiatrists|
|2018||Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Heilbronner, U. ... Cervantes, P. (2018). Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.. JAMA psychiatry, 75, 1, 65-74.
|2017||Schubert, K., Air, T., Clark, S., Grzeskowiak, L., Miller, E., Dekker, G. ... Clifton, V. (2017). Trajectories of anxiety and health related quality of life during pregnancy. PLoS ONE, 12, 7, e0181149-1-e0181149-14.
|2017||Clark, S., Warren, N., Kim, G., Jankowiak, D., Schubert, K., Kisely, S. ... Siskind, D. (2017). Elevated clozapine levels associated with infection: A systematic review. Schizophrenia Research, -.
|2017||Schubert, K., Clark, S., Van, L., Collinson, J. & Baune, B. (2017). Depressive symptom trajectories in late adolescence and early adulthood: A systematic review. Australian and New Zealand Journal of Psychiatry, 51, 5, 477-499.
|2017||Myles, N., Myles, H., Clark, S., Bird, R. & Siskind, D. (2017). Use of granulocyte-colony stimulating factor to prevent recurrent clozapine-induced neutropenia on drug rechallenge: A systematic review of the literature and clinical recommendations. Australian and New Zealand Journal of Psychiatry, 51, 10, 980-989.
|2016||Clark, S., Baune, B., Schubert, K., Lavoie, S., Smesny, S., Rice, S. ... Amminger, G. (2016). Prediction of transition from ultra-high risk to first-episode
psychosis using a probabilistic model combining history,
clinical assessment and fatty-acid biomarkers. Translational Psychiatry, 6, 9, 1-8.
|2016||Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N. ... Cousins, D. (2016). Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. The Lancet, 387, 10023, 1085-1093.
|2015||Clark, S., Schubert, K. & Baune, B. (2015). Towards indicated prevention of psychosis: using probabilistic assessments of transition risk in psychosis prodrome. Journal of Neural Transmission, 122, 1, 155-169.
|2015||McGorry, P. D. (2015). Australian Early Psychosis Research Network: national collaboration, international competitive advantage. The Medical Journal of Australia, 202, 4, 170-171.
|2015||Jaehne, E., Ramshaw, H., Xu, X., Saleh, E., Clark, S., Schubert, K. ... Baune, B. (2015). In-vivo administration of clozapine affects behaviour but does not reverse dendritic spine deficits in the 14-3-3ζ KO mouse model of schizophrenia-like disorders. Pharmacology Biochemistry and Behavior, 138, 1-8.
|2015||Tan, L., Suetani, S., Clark, S. & Wilson, D. (2015). Late onset myocarditis with clozapine use. Australian and New Zealand Journal of Psychiatry, 49, 3, 295-.
|2015||Oliver Schubert, K., Clark, S. & Baune, B. (2015). The use of clinical and biological characteristics to predict outcome following first episode psychosis. Australian and New Zealand Journal of Psychiatry, 49, 1, 24-35.
|2014||Clark, S., Wilton, L., Baune, B., Procter, N. & Hustig, H. (2014). A state-wide quality improvement system utilising nurse-led clinics for clozapine management. Australasian Psychiatry, 22, 3, 254-259.
|2013||Fitzpatrick, A., Clark, S., Newcombe, R., Davis, A. & Baune, B. (2013). Fingolimod exacerbated affective psychosis?. Australian and New Zealand Journal of Psychiatry, 47, 4, 399-400.
|2013||Manchia, M. & Baune, B. (2013). Assessment of response to lithium maintenance treatment in bipolar disorder: a consortium on lithium genetics (ConLiGen) report. PLoS One, 8, 6, 1-9.
|2005||Clark, S., Pradhan, M., Adams, R., Faunt, J., Hill, A. & Guterres, A. (2005). Opportunities to reduce delay to antibiotic in community acquired pneumonia: early diagnosis modelling and simulation. National Health Informatics Conference. Melbourne, Victoria, Australia.|
|2003||Clark, S., Pradhan, M., Adams, R., Faunt, J. & Hill, A. (2003). Workflow assessment. National Royal Australian College of General Practitioners Computer Conference and National Health Informatics Conference. Sydney, NSW, Australia.|
|2000||Clark, S. R. & Pradhan, M. (2000). A Comparison Of A Paper-Based Clinical Guideline And A Decision Support System For The Management of Community Acquired Pneumonia.. Health Informatics Conference 2000 - Integrating Information for Health Care. M. Pradhan (Ed.) Adelaide.|
|2017||Clark, S., Amminger, P., Lin, A., Schubert, K. O., Pantelis, C., Yung, A. ... Nelson, B. (2017). PROBABILISTIC MODELING OF TRANSITION TO PSYCHOSIS USING CLINICAL AND COGNITIVE VARIABLES IN THE PERSONAL ASSESSMENT AND CRISIS EVALUATION ("PACE 400") STUDY. 16th International Congress on Schizophrenia Research (ICOSR). San Diego, CA.|
|2015||Schubert, K. O., Wylde, C. P., Clark, S. R. & Baune, B. T. (2015). Are Deficits in the Verbal Comprehension Index (VCI) of the Wechsler Adult Intelligence Scale (WAIS) associated with clinical and functional outcomes in Schizophrenia?. Australasian Schizophrenia Conference 2015. Melbourne.|
|2015||Clark, S. R., Kim, G., Jankowiak, D., Schubert, K. O. & Baune, B. T. (2015). Multiple mechanisms of clozapine toxicity related to infection. Society of Mental Health Research Conference 2015. Brisbane.|
|2015||Baune, B., Clark, S., Schubert, O., Rice, S., Vijayakumar, N., Schaefer, M. ... Amminger, P. (2015). Oxidative Markers for Prediction of Transition to Psychosis From the Clinical High-risk State.
|2015||Clark, S. R., Schubert, K. O., Rice, S., Vijayakumar, N., Schäfer, M., McGorry, P. D. ... Amminger, G. P. (2015). Can we predict psychosis in a frontline clinical setting?. Australasian Schizophrenia Conference. Melbourne.|
|2015||Siskind, D., Clark, S. R., Kisely, S., Rosenheck, R., Smith, G. & Whitehead, J. (2015). Managing Metabolic Adverse Drug Reactions Associated with Clozapine Treatment for People with Treatment Refractory Schizophrenia. Society for Mental Health Research. Brisbane.|
|2015||Clark, S. R., Schubert, K. O. & Baune, B. T. (2015). PROBABILISTIC ASSESSMENTS OF TRANSITION RISK IN THE PSYCHOSIS PRODROME. 15th International Congress on Schizophrenia Research (ICOSR). Colorado Springs, CO.
|2015||Baune, B., Schubert, O. & Clark, S. (2015). Indicated Prevention in Clinical High Risk (Chr) for First Episode Psychosis (Fep): the Utility of an Extended Diagnostic Approach..
|2014||Clark, S. R., Arolt, V., Bayrakci, B. & Baune, B. T. (2014). Long-term symptoms and functional trajectories of patients with major depressive disorder post hospital discharge.. Society for Mental Health Research. Adelaide.|
|2014||Schubert, K. O., Higgs, L., McKay, S., Baune, B. T., Clark, S. R., Rafalowicz, E. ... Mylvaganam, S. (2014). EPIS North: a consultation-based Early Psychosis Intervention Programme supporting a general adult community mental health service.. Society for Mental Health Research (SMHR) Annual Conference. Adelaide.|
|2014||Clark, S. R., Baune, B. T., Schubert, K. O., Rice, S., Vijayakumar, N., Schäfer, M. R. ... Amminger, G. P. (2014). Modeling trajectories in clinical high risk of psychosis. Society for Mental Health Research. Adelaide.|
|2014||Clark, S. R., Wilton, L., Donohoe, P., Schubert, K. O. & Baune, B. T. (2014). General Practice based public-private clozapine monitoring.. Society for Mental Health Research. Adelaide.|
|2014||Suetani, S., Oh, H. & Clark, S. R. (2014). Clozapine and Constipation. Society for Mental Health Research. Adelaide.|
|2013||Clark, S. R. (2013). Rural Intermediate Care in South Australia: a perspective on the first 12 months.. 12th National Rural Health Conference. Adelaide.|
|2012||Clark, S. R. & Wilton, L. (2012). Clozapine: A Statewide Systems Approach to Improving the Quality of Care.. Royal Australian and New Zealand College of Psychiatrists’ Congress. Hobart.|
|2012||Clark, S. R. & Mosler, D. (2012). The Specialist Training Program in the South Australian Distance Consultation Service.. Royal Australian and New Zealand College of Psychiatry Congress. Hobart.|
|2011||Clark, S. R. & Wilton, L. (2011). Clozapine – Nurse Led Clinics - The dream. The coordination required to achieve consistency of practice and information flow - The reality.. 2nd Annual Mental Health Units Conference. Sydney.|
|2009||Clark, S. R.; (2009); Decision support systems for the treatment of community-acquired pneumonia;|
|2014 - ongoing||Member||Society for Mental Health Research||Australia|
|2014 - ongoing||Member||Fellow of the Royal Australian College of Psychiatrists||Australia|
|2014 - ongoing||Member||Australian Early Psychosis Research Network||Australia|
|2009 - ongoing||Member||Health Informatics Society of Australia||Australia|
|2016 - ongoing||Member||RANZCP Research Committee||Royal Australian & New Zealand College of Psychiatry||Australia|
|2015 - ongoing||Member||EPAS Clozapine order set working group||SA Health||Australia|
|2014 - ongoing||Member||Clozapine Focus Group||SA Health||Australia|
|2013 - 2014||Member||Australian Society for Mental Health Research 2014 conference||University of Adelaide||Australia|
|2012 - ongoing||Member||EPAS Mental Health Clinical Working Party||SA Health||Australia|
|2010 - ongoing||Chair||Adelaide Metropolitan Clozapine Working Group||SA Health||Australia|
|2016 - 2016||Adelaide Primary Health Care Network||Business and professional||Australia|