Dr Sanam Mustafa
ARC Grant-Funded Researcher B
School of Biomedicine
Faculty of Health and Medical Sciences
Dr Sanam Mustafa is at the University of Adelaide and Science Technology Australia’s inaugural Superstar of STEM. An internationally trained molecular pharmacologist , Sanam has developed and leads multidisciplinary and multi-institute research programs that will revolutionise pain management and quantification.Sanam’s academic excellence has been reflected in successful competitive funding (>$4,500,000) funding and her contributions have been recognised by a number of awards, prizes & invited talks. She was recently awarded the University of Adelaide’s Executive Dean’s Medal for Engagement and Advancement for successfully leading a nationally competitive bid to engage with Defence to host a symposium attended by over 100 leading researchers and defence personnel. Demonstrating her reputation as a leading pain researcher, Sanam presented developments in pain management at Royal Australasian College of Surgeons; shared novel concepts for understanding pain signalling at Pain Adelaide; was invited to address Military officials on the importance of the neuroimmune system. In recognition of her successful research approach, Sanam was invited by ARC Centre for Plant Energy Biology to share her insights on the benefits of multidisciplinary research.As a successful first-generation woman in STEM, Sanam leads by positive example to mentor the next generation of researchers, including over 20 student supervisions. A leader among her peers, she represents them at executive levels across the sector, including as Vice President of BliSS Science and Innovation inc. and Chair of BLiSS*Adelaide Chapter – a non-profit organisation fostering & enabling multidisciplinary collaborations. Sanam led a team of 15 to raise over $40,000 in sponsorship and attract over 200 registrants from all the Universities and major research institutions in Adelaide in 2019 and 2020. Sanam contributes actively and positively to the broader science conversation and was interviewed by Nature Careers for an article on media interviews. A passionate advocate for gender, equity and inclusion, Sanam is on the board of aKIDemic Life and a member of multiple committees. Sanam’s invited piece for The Conversation on what Australia needs from the Ambassador for Women in Science received international attention reaching over 4000 reads in two weeks. Sanam has discussed issues facing women in STEM during a radio interview with the Wire and was an invited panel discussion member at a Diversity and Inclusion workshop being held as part of the ASCEPT Annual Scientific Meeting in Adelaide November 2018.
A molecular pharmacologist trained in one of the world’s most renowned research laboratories, Dr Sanam Mustafa now leads a program of independent research. Working closely with the Neuroimmunopharmacology group led by Prof Mark Hutchinson, her research focusses on determining the fundamental biological processes governing the communication between the brain and immune system.
While the immune system critically influences pain, sleep, fertility and protective responses to chemical, biological, radiological and nuclear (CBRN) exposure, researchers lack the technologies to better understand the fundamental process involved in immune signalling and regulation. New tools that provide detailed real-time characterisation of immune signalling are urgently needed. Due to Sanam's unique skillset and experience in developing tools for probing complex intracellular signalling, in response to this problem she has developed a platform technology named illuminating TLR4 assay (iTLR4 assay). Utilising iTLR4 assay, her team has generated data which for the first time allows real-time measurement of a key innate immune receptor, Toll-like receptor 4 (TLR4). iTLR4 is the only assay that can measure real-time ligand dependent conformation changes in TLR4.
Recognised as a scientific leader, Sanam was awarded the Faculty of Health and Medical Sciences (FHMS) Executive Dean’s medal for Engagement & Advancement and Science & Technology Australia (STA) named her an inaugural ‘Superstar of STEM’. Sanam has built strong industry and professional networks serving as Vice President for BLiSS Science & Innovation Inc - a non-profit organisation fostering & enabling multidisciplinary collaborations and has also fostered ongoing engagement with Defence Science & Technology Group (DSTG) as a key academic contact in Adelaide.
A passionate advocate for human rights and gender equity, Sanam has served on multiple committees including STA’s Diversity and Inclusion committee and is currently on the board of Academics for Palestine-South Australia and aKIDemic Life. As a successful first-generation woman in STEM, Sanam leads by positive example to mentor the next generation of researchers and represents her peers at executive levels across the sector.
Background
Dr Sanam Mustafa completed her undergraduate studies at the University of Glasgow, graduating in 2004 with a M.Sci (Honours) in Genetics. This included an Industrial work placement year at the Comparative Genomics department of GlaxoSmithKline (GSK). Sanam then trained in one of the world's leading laboratories researching GPCRs under the supervision of Prof Graeme Milligan and Dr Alan Wise. This PhD studentship was co-funded by the Biotechnology and Biological Sciences Research Council and GSK. During her case studentship, Sanam had the invaluable opportunity to spend 3 months in the high throughput-screening department of GSK.
Following a short postdoctoral position in collaboration with Almiral, in 2009 Sanam joined A/Prof Kevin Pfleger's group at the Western Australian Institute for Medical Research at the University of Western Australia. Here Sanam expanded her skill-set to encompass the study of protein-protein interactions at a more detailed level. Alongside academic research projects, Sanam managed contract research work for Dimerix Bioscience. This included project management of a research contract outsourced by Takeda Cambridge. Other responsibilities included the teaching and examination of undergraduate students.
In her role as Research Fellow at the Australian Research Council, Centre of Excellence for Nanoscale BioPhotonics (CNBP), University of Adelaide, Sanam worked closely with physicists and chemists to develop novel light based technologies for sensing and investigating intracellular signalling.
Her skill-set includes techniques such as molecular biology (PCR, RT-PCR), confocal microscopy, immunocytochemistry, Bioluminescence Resonance Energy Transfer (BRET), chemotaxis, ERK, [32P] orthophosphate phosphorylation and ELISA assays.
| Date | Position | Institution name |
|---|---|---|
| 2024 - 2025 | Senior Lecturer | University of Adelaide |
| 2024 - 2025 | Senior Researcher Fellow C | University of Adelaide |
| 2021 - 2024 | ARC Grant-Funded Researcher B | University of Adelaide |
| 2014 - 2021 | ARC Senior Research Fellow | University of Adelaide |
| 2013 - 2014 | Research Associate | University of Adelaide |
| 2013 - 2013 | Scientific and medical writer | iX Biopharma Limited |
| 2013 - 2013 | Case Based Learning tutor | University of Adelaide |
| 2009 - 2011 | Postdoctoral Research Associate | University of Western Australia |
| 2009 - 2009 | Postdoctoral Researcher | University of Glasgow |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2019 | Award | Executive Dean’s Medal for Engagement and Advancement | University of Adelaide | Australia | - |
| 2018 | Award | CNBP Director's Award | University of Adelaide | Australia | - |
| 2017 | Recognition | Science and Technology Australia inaugural Superstar of STEM | Science and Technology Australia | Australia | - |
| 2014 | Award | CNBP Director's Award | University of Adelaide | Australia | - |
| 2010 | Award | Prize for best poster | - | - | - |
| 2007 | Award | Prize for best poster | - | - | - |
| 2007 | Award | Prize for best poster | - | - | - |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2004 - 2008 | University of Glasgow | United Kingdom | PhD in Molecular Pharmacology |
| 1999 - 2004 | University of Glasgow | United Kingdom | M.Sci (Honours) |
| Year | Citation |
|---|---|
| 2022 | Mustafa, S., Evans, S., Barry, B., Barratt, D., Wang, Y., Lin, C., . . . Hutchinson, M. R. (2022). Toll-Like Receptor 4 in Pain: Bridging Molecules-to-Cells-to-Systems.. In V. Kumar (Ed.), Toll-like Receptors in Health and Disease. Handbook of Experimental Pharmacology (Vol. 276, pp. 239-273). Springer Berlin Heidelberg. DOI Scopus2 Europe PMC2 |
| 2015 | Thomas, J., Sanam, M., Johnson, J., & Nicotra, L. (2015). The relationship between opioids and immune signalling in the spinal cord. In Handbook of Experimental Pharmacology (Vol. 227, pp. 207-238). Springer Berlin Heidelberg. DOI Scopus20 Europe PMC15 |
| Year | Citation |
|---|---|
| 2019 | Dunning, K. R., Campugan, C., Tan, C., Mahbub, S., Goldys, E., Thompson, J., . . . Mustafa, S. (2019). Hyperspectral imaging of the early embryo: can it detect chromosome abnormalities and predict IVF success?. In Label-free Biomedical Imaging and Sensing (LBIS) Vol. 10890:108900I (pp. 1-3). online: SPIE. DOI Scopus2 WoS1 |
| 2016 | Staikopoulos, V., Gosnell, M., Anwer, A., Mustafa, S., Hutchinson, M., & Goldys, E. (2016). Hyperspectral imaging of endogenous fluorescent metabolic molecules to identify pain states in central nervous system tissue. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 1-8). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING. DOI Scopus3 WoS3 |
| 2016 | Peddie, V., Heng, S., Mustafa, S., Thomas, J., Hutchinson, M., & Abell, A. (2016). Shapeshifting photoswitchable azobenzene compounds and their biological applications. In M. Hutchinson, & E. Goldys (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 10013 (pp. 4 pages). Adelaide, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2010 | Godessarti, N., Mustafa, S., Dolgachev, V., Auli, M., Aguilar, N., Cabedo, J., . . . Tarrason, G. (2010). The S1P1 receptor antagonist W146 induces lymphopenia in mice. Demonstration that functional antagonism of S1P1 is the mechanism of lymphopenia evoked by fingolimod-like compounds.. In JOURNAL OF IMMUNOLOGY Vol. 184 (pp. 1 page). AMER ASSOC IMMUNOLOGISTS. |
|
CI Mustafa 2025 Centre for Advanced Defence Research and Enterprise $50,000 CI Mustafa 2025 ISSLS Clinical Science Research Grant Award, $20,000 USD CI Mustafa 2024 Russell Cole Memorial ANZCA Research Award, $132,753 CI Mustafa 2024 Centre for Advanced Defence Research and Enterprise $150,000 CIA Mustafa 2022 DSTG, DMTC A Real-Time Innate Immune Screening Technology (ARTIIST), $225,000 CI Mustafa 2022 DSTG, DMTC The Human Integrated Sensor System Challenge, $3,000,000 CI Mustafa 2020 DSTG, Measurement Enabled Precision Human Performance, Industry Competitive Evaluation Research Agreement (ICERA) with Biosensis, $300,000 CI Mustafa 2020 NGTF Human Biotechnologies: Performance Patch and Technology Trajectory $500,000 CI Mustafa 2020 Air Force Office of Scientific Research - The neuroimmune interface, $75,000 CI Mustafa 2019 DSTG, NGTF Human Biotechnologies: Performance Patch and Technology Trajectory, $500,000 CIA Mustafa 2019 FHMS, Emerging Leadership Development Program, $40,000 CI Mustafa 2018 USA Air Force Office of Scientific Research (AFOSR) The neuroimmune interface, $75,000 CI Mustafa 2017 Barbara Kidman Fellowship CI Mustafa 2017–2020 AFOSR Shining the light on the neuroimmune interface, $225,000 CI Mustafa 2013 Institute for Photonics Advanced Sensing (IPAS) Extending Collaborations Pilot Project, $20,000 CI Mustafa 2013 IPAS Extending Collaborations Pilot Project, $2,000
Monetary Awards
The School of Medical Sciences awarded 13,500 AUD for the purchase of centrifuge equipment in July 2015. |
| The ARC Centre of Excellence for Nanoscale BioPhotonics awarded 19,000 AUD in May 2015 towards the purchase of equipment for a cell culture facility. |
| 8908 AUD was awarded by the School of Medical Sciences towards the purchase of automated cell counters in October 2014. |
| The University of Western Australia awarded 750 AUD towards the cost of attending the ELRIG Drug Discovery Conference in Manchester in September 2011. |
| Recipient of the Tony B academic travel award (>3000 USD) to attend SLAS LabAutomation meeting in Palm Springs, January 2011. |
| A 500 AUD travel award was granted by the organizers towards the attendance of the Molecular Pharmacology GPCR meeting in Melbourne in December 2010. |
| Successful for two travel awards; 1000 AUD from WAIMR and a further 750 AUD from the University of Western Australia, to attend the ELRIG Drug Discovery Conference in Coventry in September 2010. |
| Awarded £100 from the British Pharmacological Society (BPS) to attend the BPS 3rd focused meeting “Cell Signalling” in Leicester in April 2009. |
- Supervision of PhD students:
- Anston Savio D'silva 2025 -
- Michail Laoumtzis 2022 -
- Laura Carr, 2021 - 2025
- Benjamin Barry, 2021 - 2025
- Cheow Yuen Tan (Tiffany), 2017 - 2022
- Mengke Han, 2017 - 2022
- Bianca Laura Guglietti, 2017-2021
- Azim Arman: 2015 - 2020.
- Samuel Evans, 2015- 2020
- Jonathan Henry Jacobsen, 2014-2017: Award of PhD and Dean's Commendation for Doctoral Thesis Excellence
- Jiajun Liu, 2014-2017: Award of PhD and Dean's Commendation for Doctoral Thesis Excellence,
- Supervision of Masters student:
- Kariel Renee Siemens, 2021-
- Supervision of Honours student:
- Laura Carr, First class Honours, 2020
- Benjamin Barry, First class Honours, 2020
- Miriam Dodds, First class Honours, 2019
- Edwina Cox, Second class Honours (2A), 2017. On time completion
- Supervision of work placement students
- Lucille Michelot, Overseas work placement student, October 2018-March 2019
- Benjamin Barry, 3 weeks 2018
- Shenyi Peng, Summer 2017-2018
- Andreas Anargyros, 4 weeks, 2017
- Lucy Carpenter, 2 weeks, 2017
- Mehrnoosh Ostovar, 6 months, 2015
- Kishan Sangani, 6 months, 2014
- Mathew Steen, Summer 2014-2015
- Regular teaching and assessment of undergraduate (SGDP) and Honours students.
Medicine Learning and Teaching Unit (MLTU), University of Adelaide
Case Based Learning tutor for 2nd year medical students (2013)
In-depth preparation for group workshop sessions, facilitation of discussions to encourage knowledge consolidation and clinical reasoning, and oral and written assessment of students including providing constructive feedback.
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Co-Supervisor | Investigating the role of TLR4 antagonists and the effects on chronic pain: a structural biology journey | Doctor of Philosophy under a Jointly-awarded Degree Agreement with | Doctorate | Full Time | Mr Anston Savio D'silva |
| 2022 | Co-Supervisor | The Human Integrated Sensor System (HISS) Challenge | Doctor of Philosophy | Doctorate | Full Time | Mr Michail Laoumtzis |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2021 - 2025 | Co-Supervisor | Exploring A20 In the Context of Neuroimmune Regulation and Pain. | Doctor of Philosophy | Doctorate | Part Time | Mr Benjamin Daniel Barry |
| 2021 - 2025 | Co-Supervisor | Exploring Microglial Ageing: Insights from Human Genomic Data, Pre-Clinical Animal Models, and the Future of In Vitro Modelling | Doctor of Philosophy | Doctorate | Full Time | Miss Laura May Carr |
| 2019 - 2022 | Co-Supervisor | Intracellular delivery and voltage sensitivity of nanomaterials for the optical imaging of neuronal activity | Doctor of Philosophy | Doctorate | Full Time | Ms Mengke Han |
| 2018 - 2022 | Co-Supervisor | Optical imaging detects metabolic signatures associated with oocyte and embryo quality | Doctor of Philosophy | Doctorate | Full Time | Miss Cheow Yuen Tan |
| 2018 - 2021 | Co-Supervisor | Targeting Cognitive Impairment in Parkinson’s Disease: Novel Pharmacological and Non-Pharmacological Approaches | Doctor of Philosophy | Doctorate | Full Time | Miss Bianca Laura Guglietti |
| 2015 - 2020 | Co-Supervisor | Investigation of a Functional Relationship Between Toll-Like Receptor 4 and Transient Receptor Potential Cation Channel Subfamily V Member 1 in Relation to a Novel Neuroimmune Pain Model | Doctor of Philosophy | Doctorate | Full Time | Mr Samuel Evans |
| 2015 - 2020 | Co-Supervisor | Advanced Preclinical Assessment of Hyper-Nociception | Doctor of Philosophy | Doctorate | Full Time | Mr Azim Arman |
| 2014 - 2017 | Co-Supervisor | Exploring the Bidirectional Interface between Stress and Innate Immunity: A Focus on Glucocorticoid and TLR4-MyD88 Signalling | Doctor of Philosophy | Doctorate | Full Time | Dr Jiajun Liu |
| 2014 - 2017 | Co-Supervisor | Exploring the Pharmacology of (+)-Naltrexone on Alcohol Reward and Anxiety Behaviours | Doctor of Philosophy | Doctorate | Full Time | Jonathan Henry Jacobsen |
| Date | Role | Board name | Institution name | Country |
|---|---|---|---|---|
| 2018 - ongoing | Advisory Board Member | aKIDemic Life | University of Tasmania | Australia |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2020 - ongoing | Member | Science & Technology Australia Equity, Diversity & Inclusion committee | Science & Technology Australia | Australia |
| 2018 - ongoing | Chair | BliSS Adelaide Steering committee | BLiSS Science & Innovation Inc | Australia |
| 2018 - ongoing | Member | IPAS Scientific Leadership Team | Institute of Photonics Advanced Sensing | Australia |
| 2018 - ongoing | Member | CNBP Nurturing Environment Committee | ARC Centre for Nanoscale BioPhotonics | Australia |
| 2018 - ongoing | Chair | DST EDTAS symposium committee | Defence Science and Technology and University of Adelaide | Australia |
| 2018 - ongoing | Member | ASCEPT Adelaide conference committee | ASCEPT | Australia |
| 2018 - 2018 | Representative | CNBP Executive Management Committee | ARC Centre for Nanoscale BioPhotonics | Australia |
| 2018 - 2018 | Member | Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Local organising committee | University of Adelaide | Australia |
| 2017 - ongoing | Member | Faculty of Health Sciences, Gender Equity and Diversity Committee | University of Adelaide | Australia |
| 2016 - ongoing | Representative | CNBP Adelaide node Early Career Researcher | ARC Centre for Nanoscale BioPhotonics | Australia |
| 2016 - ongoing | Member | ECR/MCR committee member | University of Adelaide | - |
| 2015 - ongoing | Chair | Biological challenges forum | ARC Centre of Excellence for Nanoscale and BioPhotonics | - |
| 2013 - ongoing | Member | Australasian Neuroscience Society (ANS) | - | - |
| 2010 - 2011 | Member | Australian Society for Medical Research (ASMR | - | - |
| 2004 - 2007 | Member | Biochemical Society | - | - |
| 2004 - ongoing | Member | British Pharmacological Society (BPS) | - | - |
| Date | Title | Engagement Type | Institution | Country |
|---|---|---|---|---|
| 2018 - ongoing | Tall Tales of Science | Public Community Engagement | National Science Week | Australia |
| 2018 - 2018 | High school visit | Public Community Engagement | Adelaide High School | Australia |
| Date | Role | Editorial Board Name | Institution | Country |
|---|---|---|---|---|
| 2022 - ongoing | Editor | Brain, Behavior, and Immunity | University of Adelaide | Australia |
| 2014 - ongoing | Board Member | Frontiers in Cellular Endocrinology | - | - |
| Date | Event Name | Event Type | Institution | Country |
|---|---|---|---|---|
| 2014 - 2014 | Nanoscale BioPhotonics ASCEPT-MPGPCR meeting | Workshop | ARC Centre for Nanoscale BioPhotonics | Australia |
| Date | Office Name | Institution | Country |
|---|---|---|---|
| 2020 - ongoing | Vice President | BLiSS Science & Innovation Inc | Australia |
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