
Oliver Schubert
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
A/Professor K. Oliver Schubert
My research focuses on the molecular underpinnings of psychiatric disorders such as schizophrenia, bipolar disorder, and major depression. I am particularly interested in transcriptomic and proteomic signatures of clinical endophenotypes (subtypes), treatment response and treatment resistance. This research is facilitated through a number of growing clinical cohorts (e.g. mood disorders, psychotic disorders, perinatal mental health) developed at the Discipline of Psychiatry, as well as through post-mortem brain research and animal models. I have a clinical special interest in Youth Mental Health and in the treatment of Early Psychosis.
Education:
2013 Royal Australian and New Zealand College of Psychiatry Australia FRANZCP
2011 The College of Psychiatry of Ireland Ireland Certificate of Satisfactory Completion of Specialist Training (CSCST)
2009 The Institute for Commercial Management United Kingdom Postgraduate Diploma in Health Service Management
2008 Royal College of Psychiatrists United Kingdom MRCPsych
2008 - 2014 Royal College of Surgeons in Ireland Ireland PhD
2000 - 2005 Institute for Anatomy and Cell Biology, University of Freiburg Germany Doctor of Medicine (MD)
1998 - 2004 University of Freiburg Germany State Exam Medicine
- My Research
- Career
- Publications
- Grants and Funding
- Teaching
- Supervision
- Professional Activities
- Contact
Research
My research focuses on the molecular underpinnings of psychiatric disorders such as schizophrenia, bipolar disorder, and major depression. I am particularly interested in transcriptomic and proteomic signatures of clinical endophenotypes (subtypes), treatment response and treatment resistance. This research is facilitated through a number of growing clinical cohorts (e.g. mood disorders, psychotic disorders, perinatal mental health) developed at the Discipline of Psychiatry, as well as through post-mortem brain research and animal models. I have a clinical special interest in Youth Mental Health and in the treatment of Early Psychosis.
Current research projects:
PROTECTIVE TRIAL (collaboration with Department of Anaesthesia - A/Professor Bernd Froessler): As part of this clinical trial (300 participants), we are investigating the impact of iron deficiency in on women’s mental health outcomes such as anxiety, depression, and cognitive function. We are also finding out whether treatment of iron deficiency by iron infusion positively influences mental health outcomes during the first year after giving birth. |
ASTHMA IN PREGNANCY STUDY (collaboration with the Robinson Institute – Professor Vicki Clifton/ Dr Luke Grzeskowiak) Over 300 participants were enrolled in this project investigating the impact of asthma on pregnancy outcomes. Several mental health parameters such as depression, anxiety, and quality of life were also assessed over the course of pregnancy, and we are specifically investigating how mental health interacts with chronic medical conditions such as asthma in pregnant women. |
COGNITIVE FUNCTION AND MOOD DISORDERS STUDY (CoFaMS) The CoFaMS project (Principal investigator: Professor Bernhard Baune) investigates the relationship between mood- and anxiety disorders and cognitive outcomes such as memory, attention, or planning ability. We are also investigating the biological underpinnings of mood disorder symptoms and responses to treatments through genetic, transcriptomic, and proteomic analyses of participant’s blood samples. Currently, >250 participants have been assessed for the CoFaMS project in South Australia. |
COGNITIVE AND AND FUNCTIONAL ASSESSMENTS IN PSYCHOSIS STAGING STUDY (CoFAPSS) The CoFAPSS project (Principal investigator: Professor Bernhard Baune) investigates the longitudinal development of psychotic symptoms, neurocognitive symptoms, and functional outcomes in people who are suffering from a psychotic disorder such as schizophrenia, schizoaffective disorder, or bipolar disorder. In order to better understand the biological drivers of disease progression in psychotic disorders, we are also collecting participant’s blood samples for genetic, transcriptomic, and proteomic analyses. |
TRAJECTORIES OF RESPONSE TO ARIPIPRAZOLE MAINTENA STUDY (TRAMS) This investigator-initiated naturalistic clinical study (Principal Investigator: Professor Bernhard Baune), supported by the Lundbeck Institute, enrolls patients with psychotic disorders such as schizophrenia or schizoaffective disorder who are treated with the recently available depot antipsychotic aripipazole maintena. The study assesses patient’s psychotic symptoms as well as their cognitive- and everyday functioning before and during the first year of treatment. |
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Appointments
Date Position Institution name 2018 - ongoing Clinical Associate Professor University of Adelaide 2016 - 2017 Clinical Senior Lecturer The University of Adelaide 2013 - 2016 Clinical Academic The University of Adelaide 2013 - ongoing Consultant Psychiatrist Northern Mental Health -
Awards and Achievements
Date Type Title Institution Name Country Amount 2015 Award Young Investigator Award International Congress on Schizophrenia Research (ICOSR) United States 2013 Award Prof. Derek Frewin Citation for Clinical Teaching 2013 School of Medicine, The University of Adelaide Australia 2012 Award Prof. Derek Frewin Citation for Clinical Teaching 2012 School of Medicine, The University of Adelaide Australia 2008 Fellowship Molecular Medicine Ireland Clinician Scientist Fellowship Molecular Medicine Ireland (MMI)/ Royal College of Surgeons in Ireland Ireland EUR 180,000 -
Education
Date Institution name Country Title 2013 Royal Australian and New Zealand College of Psychiatry Australia FRANZCP 2011 The College of Psychiatry of Ireland Ireland Certificate of Satisfactory Completion of Specialist Training (CSCST) 2009 The Institute for Commercial Management United Kingdom Postgraduate Diploma in Health Service Management 2008 - 2014 Royal College of Surgeons in Ireland Ireland PhD 2008 Royal College of Psychiatrists United Kingdom MRCPsych 2000 - 2005 Institute for Anatomy and Cell Biology, University of Freiburg Germany Doctor of Medicine (MD) 1998 - 2004 University of Freiburg Germany State Exam Medicine -
Research Interests
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Journals
Year Citation 2022 Cearns, M., Amare, A. T., Schubert, K. O., Thalamuthu, A., Frank, J., Streit, F., . . . Baune, B. T. (2022). Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach. The British Journal of Psychiatry, 220(4), 219-228.
2021 Amare, A., Schubert, K. O., Thalamuthu, A., Clark, S., Schulze, T. G., Rietschel, M., & Baune, B. (2021). TH69. COMBINING SCHIZOPHRENIA AND DEPRESSION POLYGENIC RISK SCORES (PRS) IMPROVES THE GENETIC PREDICTION OF LITHIUM RESPONSE IN BIPOLAR DISORDER PATIENTS. European Neuropsychopharmacology, 51, e231.
2021 Thalamuthu, A., Mills, N. T., Berger, K., Minnerup, H., Grotegerd, D., Dannlowski, U., . . . Baune, B. T. (2021). Genome-wide interaction study with major depression identifies novel variants associated with cognitive function.. Mol Psychiatry, 27(2), 9 pages.
2021 Schubert, K. O., Thalamuthu, A., Amare, A. T., Frank, J., Streit, F., Adl, M., . . . Baune, B. T. (2021). Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry, 11(1), 8 pages.
Scopus2 WoS1 Europe PMC12021 Bidargaddi, N., Schrader, G., Myles, H., Schubert, K. O., van Kasteren, Y., Zhang, T., . . . Strobel, J. (2021). Demonstration of automated non-adherence and service disengagement risk monitoring with active follow-up for severe mental illness. Australian and New Zealand Journal of Psychiatry, 55(10), 976-982.
2021 Kalman, J., Clark, S., Baune, B., Schubert, K. O., Schulze, T., & Ophoff, R. (2021). Characterization of Age and Polarity at Onset in Bipolar Disorder. medRxiv.
2021 Baune, B. T., Sampson, E., Louise, J., Hori, H., Schubert, K. O., Clark, S. R., . . . Fourrier, C. (2021). No evidence for clinical efficacy of adjunctive celecoxib with vortioxetine in the treatment of depression: A 6-week double-blind placebo controlled randomized trial.. Eur Neuropsychopharmacol, 53, 34-46.
Scopus4 WoS4 Europe PMC22021 Kalman, J. L., Olde Loohuis, L. M., Vreeker, A., McQuillin, A., Stahl, E. A., Ruderfer, D., . . . Ophoff, R. A. (2021). Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry, 219(6), 659-669.
Scopus1 WoS1 Europe PMC12021 Le Clerc, S., Lombardi, L., Baune, B. T., Amare, A. T., Schubert, K. O., Hou, L., . . . Tamouza, R. (2021). HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders. Scientific Reports, 11(1), 17823-1-17823-12.
Scopus1 WoS1 Europe PMC12021 Jernbom Falk, A., Galletly, C., Just, D., Toben, C., Baune, B. T., Clark, S. R., . . . Schubert, K. O. (2021). Autoantibody profiles associated with clinical features in psychotic disorders. Translational Psychiatry, 11(1), 9 pages.
2021 Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., . . . Binder, E. B. (2021). Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry, 26(6), 2457-2470.
Scopus15 WoS21 Europe PMC112021 Miles, A. E., Dos Santos, F. C., Byrne, E. M., Renteria, M. E., McIntosh, A. M., Adams, M. J., . . . Nikolova, Y. S. (2021). Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk. Neuropsychopharmacology, 46(13), 2304-2311.
2020 Ciobanu, L. G., Sachdev, P. S., Trollor, J. N., Reppermund, S., Thalamuthu, A., Mather, K. A., . . . Baune, B. T. (2020). Downregulated transferrin receptor in the blood predicts recurrent MDD in the elderly cohort: a fuzzy forests approach. Journal of Affective Disorders, 267, 42-48.
Scopus5 WoS7 Europe PMC42020 Scott, J., Etain, B., Manchia, M., Brichant-Petitjean, C., Geffory, P., Schulze, T., . . . Schubert, K. (2020). An examination of the quality and performance of the Alda scale for classifying lithium response phenotypes. Bipolar Disorders, 22(3), 255-265.
Scopus16 WoS132020 Soda, T., McLoughlin, D. M., Clark, S. R., Oltedal, L., Kessler, U., Haavik, J., . . . Baune, B. T. (2020). International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic).. Eur Arch Psychiatry Clin Neurosci, 270(7), 921-932.
Scopus10 WoS10 Europe PMC62020 Fourrier, C., Sampson, E., Hori, H., Schubert, K. O., Clark, S., Mills, N. T., & Baune, B. T. (2020). Exploratory study of association between blood immune markers and cognitive symptom severity in major depressive disorder: Stratification by body mass index status. Brain, Behavior, and Immunity, 88, 242-251.
Scopus4 WoS5 Europe PMC32020 Zulfic, Z., Liu, D., Lloyd, C., Rowan, J., & Schubert, K. O. (2020). Is telepsychiatry care a realistic option for community mental health services during the COVID-19 pandemic?. Australian and New Zealand Journal of Psychiatry, 54(12), 1228.
Scopus12 WoS10 Europe PMC42020 Thomson, S., Doan, T., Liu, D., Schubert, K. O., Toh, J., Boyd, M. A., & Galletly, C. (2020). Supporting the vulnerable: developing a strategic community mental health response to the COVID-19 pandemic. Australasian Psychiatry, 28(5), 492-499.
Scopus9 WoS9 Europe PMC52019 Janos, K., Serg, P., Clark, S. R., Schubert, K. O., Baune, B. T., & Schulze, T. (2019). Investigating polygenic burden in age at disease onset in bipolar disorder: findings from an international multicentric study.. Bipolar Disorders, 21(1), 68-75.
Scopus15 WoS15 Europe PMC112019 Amare, A. T., Schubert, K. O., Tekola-Ayele, F., Hsu, Y. H., Sangkuhl, K., Jenkins, G., . . . Baune, B. T. (2019). The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression. Journal of Neural Transmission, 126(1), 35-45.
Scopus12 WoS12 Europe PMC82018 Amare, A., Oliver Schubert, K., Hou, L., Clark, S., Papiol, S., Cearns, M., . . . Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. (2018). Polygenic scores for major depressive disorder and depressive symptoms predict response to lithium in patients with bipolar disorder.
2018 Clark, S. R., Schubert, K. O., Olagunju, A. T., Lyrtzis, E. A., & Baune, B. T. (2018). Cognitive and Functional Assessment of Psychosis Stratification Study (CoFAPSS): Rationale, Design, and Characteristics. Frontiers in Psychiatry, 9, 10 pages.
2018 Stacey, D., Schubert, K., Clark, S., Amare, A., Milanesi, E., Maj, C., . . . Baune, B. (2018). A gene co-expression module implicating the mitochondrial electron transport chain is associated with long-term response to lithium treatment in bipolar affective disorder. Translational Psychiatry, 8(1), 183-1-183-11.
Scopus14 WoS10 Europe PMC72018 Ciobanu, L., Sachdev, P., Trollor, J., Reppermund, S., Thalamuthu, A., Mather, K., . . . Baune, B. (2018). Co-expression network analysis of peripheral blood transcriptome identifies dysregulated protein processing in endoplasmic reticulum and immune response in recurrent MDD in older adults. Journal of Psychiatric Research, 107, 19-27.
Scopus16 WoS15 Europe PMC62018 Amare, A., Schubert, K., Hou, L., Clark, S., Papiol, S., Heilbronner, U., . . . Baune, B. (2018). Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: a genome-wide association study. JAMA psychiatry, 75(1), 65-74.
Scopus88 WoS78 Europe PMC432018 Schubert, K., Stacey, D., Arentz, G., Clark, S., Air, T., Hoffmann, P., & Baune, B. (2018). Targeted proteomic analysis of cognitive dysfunction in remitted major depressive disorder: Opportunities of multi-omics approaches towards predictive, preventive, and personalized psychiatry. Journal of Proteomics, 188, 63-70.
Scopus13 WoS12 Europe PMC82018 Amare, A., Schubert, K., Tekola-Ayele, F., Hsu, Y., Sangkuhl, K., Jenkins, G., . . . Baune, B. (2018). Association of the polygenic scores for personality traits and response to selective serotonin reuptake inhibitors in patients with major depressive disorder. Frontiers in Psychiatry, 9(MAR), 65-1-65-11.
Scopus25 WoS23 Europe PMC92018 Reinbold, C. S., Clark, S. R., Schubert, K. O., Baune, B. T., & Cichon, S. (2018). Analysis of the influence of microRNAs in Lithium Response in Bipolar Disorder. Frontiers in Psychiatry, 9(MAY), 207-1-207-9.
Scopus19 WoS15 Europe PMC102018 Schubert, K. O., & Wisdom, A. (2018). Should the Australian Therapeutic Goods Administration recommend rapid dosing of lithium carbonate in acute mania?. Australian and New Zealand Journal of Psychiatry, 52(4), 387.
Scopus2 WoS2 Europe PMC22017 Grzeskowiak, L., Smith, B., Roy, A., Schubert, K., Baune, B., Dekker, G., & Clifton, V. (2017). Impact of a history of maternal depression and anxiety on asthma control during pregnancy. Journal of Asthma, 54(7), 706-713.
Scopus14 WoS13 Europe PMC32017 Clark, S., Schubert, K., & Baune, B. (2017). How Early Can We Predict and Prevent Psychosis?. Australasian Science, 38(4), 36-37. 2017 Schubert, K., Air, T., Clark, S., Grzeskowiak, L., Miller, E., Dekker, G., . . . Clifton, V. (2017). Trajectories of anxiety and health related quality of life during pregnancy. PLoS ONE, 12(7), e0181149-1-e0181149-14.
Scopus19 WoS18 Europe PMC102017 Amare, A., Schubert, K., & Baune, B. (2017). Pharmacogenomics in the treatment of mood disorders: Strategies and Opportunities for personalized psychiatry. EPMA Journal, 8(3), 211-227.
Scopus56 WoS50 Europe PMC282017 Amare, A., Schubert, K., Klingler-Hoffmann, M., Cohen-Woods, S., & Baune, B. (2017). The genetic overlap between mood disorders and cardiometabolic diseases: A systematic review of genome wide and candidate gene studies. Translational Psychiatry, 7(1), 1-12.
Scopus142 WoS139 Europe PMC762017 Clark, S., Warren, N., Kim, G., Jankowiak, D., Schubert, K., Kisely, S., . . . Siskind, D. (2017). Elevated clozapine levels associated with infection: a systematic review. Schizophrenia Research, 192, 50-56.
Scopus59 WoS51 Europe PMC282017 Clark, S., Amminger, P., Lin, A., Schubert, K. O., Pantelis, C., Yung, A., . . . Nelson, B. (2017). PROBABILISTIC MODELING OF TRANSITION TO PSYCHOSIS USING CLINICAL AND COGNITIVE VARIABLES IN THE PERSONAL ASSESSMENT AND CRISIS EVALUATION ("PACE 400") STUDY. SCHIZOPHRENIA BULLETIN, 43, S101. 2017 Schubert, K. O., Clark, S. R., Van, L. K., Collinson, J. L., & Baune, B. T. (2017). Depressive symptom trajectories in late adolescence and early adulthood: A systematic review. Australian and New Zealand Journal of Psychiatry, 51(5), 477-499.
Scopus49 WoS46 Europe PMC182017 Amare, A., Schubert, K. O., Hou, L., Clark, S., Papiol, S., Heilbronner, U., . . . Baune, B. (2017). High genetic loading of schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis. biorxiv, 48 pages.
2016 Schubert, K., Foecking, M., Wynne, K., & Cotter, D. (2016). Proteome and pathway effects of chronic haloperidol treatment in mouse hippocampus. Proteomics, 16(3), 532-538.
Scopus6 WoS5 Europe PMC52016 Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., . . . Schulze, T. (2016). Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. The Lancet, 387(10023), 1085-1093.
Scopus206 WoS178 Europe PMC1092016 Clark, S., Baune, B., Schubert, K., Lavoie, S., Smesny, S., Rice, S., . . . Amminger, G. (2016). Prediction of transition from ultra-high risk to first-episode psychosis using a probabilistic model combining history, clinical assessment and fatty-acid biomarkers. Translational Psychiatry, 6(9), 1-8.
Scopus45 WoS42 Europe PMC212016 Schubert, K., Weiland, F., Baune, B., & Hoffmann, P. (2016). The use of MALDI-MSI in the investigation of psychiatric and neurodegenerative disorders: a review. Proteomics, 16(11-12), 1747-1758.
Scopus25 WoS25 Europe PMC122016 Schubert, K., Stacey, D., Air, T., & Baune, B. (2016). Peripheral blood gene expression analysis implicates B lymphocyte proliferation and ribosomal S26 transcripts in cognitive dysfunction in people with remitted Major Depression. Journal of Affective Disorders, 190, 754-756.
Scopus5 WoS5 Europe PMC32015 Schubert, K., Föcking, M., & Cotter, D. (2015). Proteomic pathway analysis of the hippocampus in schizophrenia and bipolar affective disorder implicates 14-3-3 signaling, aryl hydrocarbon receptor signaling, and glucose metabolism: potential roles in GABAergic interneuron pathology. Schizophrenia Research, 167(1-3), 64-72.
Scopus53 WoS53 Europe PMC372015 Clark, S., Schubert, K., & Baune, B. (2015). Towards indicated prevention of psychosis: using probabilistic assessments of transition risk in psychosis prodrome. Journal of Neural Transmission, 122(1), 155-169.
Scopus24 WoS28 Europe PMC132015 Oliver Schubert, K., Clark, S., & Baune, B. (2015). The use of clinical and biological characteristics to predict outcome following First Episode Psychosis. Australian and New Zealand Journal of Psychiatry, 49(1), 24-35.
Scopus23 WoS24 Europe PMC142015 McGorry, P. D. (2015). Australian Early Psychosis Research Network: national collaboration, international competitive advantage. The Medical Journal of Australia, 202(4), 170-171.
2015 Clark, S. R., Schubert, K. O., & Baune, B. T. (2015). PROBABILISTIC ASSESSMENTS OF TRANSITION RISK IN THE PSYCHOSIS PRODROME. SCHIZOPHRENIA BULLETIN, 41(suppl 1), S14-S15.
2015 Jaehne, E., Ramshaw, H., Xu, X., Saleh, E., Clark, S., Schubert, K., . . . Baune, B. (2015). In-vivo administration of clozapine affects behaviour but does not reverse dendritic spine deficits in the 14-3-3ζ KO mouse model of schizophrenia-like disorders. Pharmacology Biochemistry and Behavior, 138, 1-8.
Scopus10 WoS9 Europe PMC62015 Baune, B., Clark, S., Schubert, O., Rice, S., Vijayakumar, N., Schaefer, M., . . . Amminger, P. (2015). Oxidative Markers for Prediction of Transition to Psychosis From the Clinical High-risk State. EUROPEAN PSYCHIATRY, 30, 1 page.
2015 Baune, B., Schubert, O., & Clark, S. (2015). Indicated Prevention in Clinical High Risk (Chr) for First Episode Psychosis (Fep): the Utility of an Extended Diagnostic Approach.. EUROPEAN PSYCHIATRY, 30, 1 page.
WoS12013 Manchia, M., & Baune, B. (2013). Assessment of response to lithium maintenance treatment in bipolar disorder: a consortium on lithium genetics (ConLiGen) report. PLoS One, 8(6), 1-9.
Scopus106 WoS97 Europe PMC592012 Schubert, K., Föcking, M., Prehn, J., & Cotter, D. (2012). Hypothesis review: are clathrin-mediated endocytosis and clathrin-dependent membrane and protein trafficking core pathophysiological processes in schizophrenia and bipolar disorder?. Molecular Psychiatry, 17(7), 669-681.
Scopus58 WoS57 Europe PMC392011 Föcking, M., Dicker, P., English, J., Schubert, K., Dunn, M., & Cotter, D. (2011). Common Proteomic Changes in the Hippocampus in Schizophrenia and Bipolar Disorder and Particular Evidence for Involvement of Cornu Ammonis Regions 2 and 3. Archives of General Psychiatry, 68(5), 477-488.
Scopus80 Europe PMC652009 Schubert, K. O., English, J. A., & Cotter, D. R. (2009). An update on the Neuropathology of Schizophrenia. Advances in Schizophrenia and Clinical Psychiatry, 4(2), 38-44. 2006 Naumann, T., Steup, A., Schnell, O., Schubert, K. O., Zhi, Q., Guijarro, C., . . . Hofmann, H. D. (2006). Altered neuronal responses and regulation of neurotrophic proteins in the medial septum following fimbria-fornix transection in CNTF- and leukaemia inhibitory factor-deficient mice. European Journal of Neuroscience, 24(8), 2223-2232.
Scopus5 Europe PMC42005 Schubert, K. O., Naumann, T., Schnell, O., Zhi, Q., Steup, A., Hofmann, H. D., & Kirsch, M. (2005). Activation of STAT3 signaling in axotomized neurons and reactive astrocytes after fimbria-fornix transection. Experimental Brain Research, 165(4), 520-531.
Scopus11 Europe PMC102003 Naumann, T., Schnell, O., Zhi, Q., Kirsch, M., Schubert, K. O., Sendtner, M., & Hofmann, H. D. (2003). Endogenous ciliary neurotrophic factor protects GABAergic, but not cholinergic, septohippocampal neurons following fimbria-fornix transection. Brain Pathology, 13(3), 309-321.
Scopus23 Europe PMC16 -
Book Chapters
Year Citation 2020 Clark, S. R., Cearns, M., Schubert, K. O., & Baune, B. (2020). Multimodal modeling for personalized psychiatry. In B. Baune (Ed.), Personalised Psychiatry (1st ed., pp. 521-536). London, United Kingdom: Academic Press.
Scopus12020 Clark, S. R., Schubert, K. O., & Baune, B. (2020). The modeling of trajectories in psychotic illness. In B. Baune (Ed.), Personalized Psychiatry (1st ed., pp. 3-12). London, United Kingdom: Academic Press.
2020 Schubert, K. O., Clark, S. R., Van, L. K., Collinson, J. L., & Baune, B. T. (2020). Mood trajectories as a basis for personalized psychiatry in young people. In B. T. Baune (Ed.), Personalized Psychiatry (pp. 13-26). London, United Kingdom: Academic Press.
2020 Cotter, D., Sabherwal, S., & Schubert, K. (2020). Proteomics for diagnostic and therapeutic blood biomarker discovery in schizophrenia and other psychotic disorders. In B. Baune (Ed.), Personalized Psychiatry (pp. 307-317). London, United Kingdom: Academic Press.
Scopus12016 Amare, A., Schubert., & Baune. (2016). Genetic Overlap Between Depression and Cardiometabolic Disorders. In Baune, & Tully (Eds.), Cardiovascular Diseases and Depression Treatment and Prevention in Psychocardiology (pp. 235-255). Switzerland: Springer.
2016 Schubert. (2016). Chapter 2. In D. Browne, & S. M. Pillay (Eds.), Master Pass Mcqs for the New Mrcpsych Paper a With Answers Explained. CRC Press. -
Conference Papers
Year Citation 2021 Schubert, K. O., Falk, A. J., Galletly, C., Just, D., Toben, C., Baune, B., . . . Manberg, A. (2021). Autoantibody profiles are associated with specific clinical features in psychotic disorders. In EUROPEAN PSYCHIATRY Vol. 64 (pp. S765-S766). CAMBRIDGE UNIV PRESS.
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Conference Items
Year Citation 2021 Ciobanu, L., Stankov, L., Heathcote, A., Clark, S., Breen, J., Rogasch, N., . . . Aidman, E. (2021). Mapping the genetic architectures of cognitive functioning. Poster session presented at the meeting of GeneMappers 2021. Virtual. 2021 Tan, K., Lawrence-Wood, E., Lawrence, A., Edwards, S., Rogasch, N., Schubert, K., . . . McFarlane, A. (2021). Trauma history is associated with a 1/f Electroencephalography signature in the MEAOP combat sample. Poster session presented at the meeting of Defence Human Sciences Symposium 2021. Melbourne. 2020 Ciobanu, L., Schubert, K. O., Amare, A., Jawahar, C., Mills, N., Knight, M., . . . Aidman, E. (2020). Genetic Pathways of Cognitive Performance are Overlapping but Distinct for General Intelligence and Executive Functioning Tasks. Poster session presented at the meeting of 2020 Virtual World Congress of Psychiatric Genetics. Virtual. 2020 Ciobanu, L., Schubert, K. O., Amare, A., Jawahar, C., Lawrence-Woods, E., Knight, M., . . . Aidman, E. (2020). Genetic Markers of Cognitive Fitness. Poster session presented at the meeting of Defence Human Sciences Symposium 2020. online. 2019 Clark, S., Stacey, D., Schubert, K. O., & Baune, B. T. (2019). Transcriptomic analyses on the biological underpinnings of lithium treatment response. Poster session presented at the meeting of 14th world cpngress of biological psychiatry. Vancouver. 2018 Clark, S., Schubert, K., Olagunju, A., Lyrtzis, E., Watson, D., & Baune, B. (2018). Trajectories in response to Aripiprazole Maintena Study: Six-month follow-up. Poster session presented at the meeting of Abstracts of the Australia and New Zealand College of Psychiatrists Congress (RANZCP 2018), as published in Australia and New Zealand Journal of Psychiatry. Auckland, New Zealand: Sage Publications.
WoS22018 Clark, S. (2018). Writing a Successful RANZCP Grant. Poster session presented at the meeting of Abstracts of the Australia and New Zealand College of Psychiatrists Congress (RANZCP 2018), as published in Australia and New Zealand Journal of Psychiatry. Auckland, New Zealand: Sage Publications.
2018 Clark, S. R., Schubert, K. O., Opel, N., Amminger, G. P., Lin, A., Pantelis, C., . . . Baune, B. T. (2018). Prediction Modelling in Psychosis: A Comparison of Simple Bayesian and Support Vector Machine Techniques.. Poster session presented at the meeting of The Human Brain Proteome Project (HBPP) Workshop 2018. Adelaide. 2018 Clark, S. R., Schubert, K. O., & Baune, B. T. (2018). Bayesian Prediction Modelling in Psychosis. Poster session presented at the meeting of World Psychiatry Association 2018 Thematic Congress. Melbourne. 2017 Clark, S. R., schubert, K. O., Olagunju, A. T., Lyrtzis, E., Watson, D., & Baune, B. T. (2017). Trajectories in response to Aripiprazole Maintena Study (TRAMS). Poster session presented at the meeting of Society for Mental Health Research Conference 2017. Canberra. 2017 Schubert, K. O., Stacey, D., Arentz., Hoffmann., & Baune. (2017). Using a Correlational Systems Biology Approach in Gene Expression and Proteomic Discovery Platforms, to characterize Cognitive Dysfunction in people with remitted Major Depression. Poster session presented at the meeting of EUROPEAN NEUROPSYCHOPHARMACOLOGY. Jerusalem, Israel: ELSEVIER SCIENCE BV.
2016 Clark, S. R., Amminger, G. P., Lin, A., Schubert, K. O., Yung, A., Wood, S., . . . Nelson, B. (2016). Prediction of transition to psychosis in the PACE 400 sample using a probabilistic model. Poster session presented at the meeting of Society for Mental Health Research Conference. Sydney. 2016 Schubert, K. O., Stacey., Arentz., Hoffmann., & Baune. (2016). Peripheral blood gene expression and proteomic analysis implicates B-cell development and ribosomal proteins in cognitive dysfunction in people with remitted Major Depression.. Poster session presented at the meeting of Human Brain Proteome Project (HBPP) Workshop. Stockholm, Sweden. 2016 Schubert, K. O., Stacey., Arentz., Hoffmann., & Baune. (2016). Gene expression and Proteomic Analysis of Cognitive Dysfunction in People with Remitted Major Depression.. Poster session presented at the meeting of 15th Human Proteome Organization World Congress. Taipei, Taiwan. 2015 Clark, S. R., Schubert, K. O., Rice, S., Vijayakumar, N., Schäfer, M., McGorry, P. D., . . . Amminger, G. P. (2015). Can we predict psychosis in a frontline clinical setting?. Poster session presented at the meeting of Australasian Schizophrenia Conference. Melbourne. 2015 Schubert, K. O., Wylde, C. P., Clark, S. R., & Baune, B. T. (2015). Are Deficits in the Verbal Comprehension Index (VCI) of the Wechsler Adult Intelligence Scale (WAIS) associated with clinical and functional outcomes in Schizophrenia?. Poster session presented at the meeting of Australasian Schizophrenia Conference 2015. Melbourne. 2015 Schubert, K. O., Stacey, D., Arentz, G., Hoffmann, P., & Baune, B. T. (2015). Peripheral blood gene expression and proteomic analysis implicates B-cell development and ribosomal proteins in cognitive dysfunction in people with remitted Major Depression. Poster session presented at the meeting of Society for Mental Health Research Conference 2015. Brisbane. 2015 Clark, S. R., Kim, G., Jankowiak, D., Schubert, K. O., & Baune, B. T. (2015). Multiple mechanisms of clozapine toxicity related to infection. Poster session presented at the meeting of Society of Mental Health Research Conference 2015. Brisbane. 2015 Schubert, K. O., Foecking, M., & Cotter, D. R. (2015). PROTEOMIC PATHWAY ANALYSIS OF THE HIPPOCAMPUS IN SCHIZOPHRENIA AND BIPOLAR AFFECTIVE DISORDER IMPLICATES 14-3-3 SIGNALING, ARYL HYDROCARBON RECEPTOR SIGNALING, AND GLUCOSE METABOLISM.. Poster session presented at the meeting of SCHIZOPHRENIA BULLETIN. Colorado Springs, CO: OXFORD UNIV PRESS.
2014 Clark, S. R., Baune, B. T., Schubert, K. O., Rice, S., Vijayakumar, N., Schäfer, M. R., . . . Amminger, G. P. (2014). Modeling trajectories in clinical high risk of psychosis. Poster session presented at the meeting of Society for Mental Health Research. Adelaide. 2014 Clark, S. R., Wilton, L., Donohoe, P., Schubert, K. O., & Baune, B. T. (2014). General Practice based public-private clozapine monitoring.. Poster session presented at the meeting of Society for Mental Health Research. Adelaide. 2014 Schubert, K. O., Higgs, L., McKay, S., Baune, B. T., Clark, S. R., Rafalowicz, E., . . . Mylvaganam, S. (2014). EPIS North: a consultation-based Early Psychosis Intervention Programme supporting a general adult community mental health service.. Poster session presented at the meeting of Society for Mental Health Research (SMHR) Annual Conference. Adelaide. 2014 Schubert, K. O. (2014). Destigmatising long acting injectables in the eyes of the carers and families. Poster session presented at the meeting of Society for Mental Health Research (SMHR) Annual Conference. Adelaide. 2011 Schubert, K. O., Foecking, M., & Cotter, D. R. (2011). Does dysfunction of clathrin mediated endocytosis contribute to synaptic pathology in psychotic disorders? A review of the evidence?. Poster session presented at the meeting of Advancing Drug Discovery for Schizophrenia, New York Academy of Science. New York. 2010 Schubert, K. O., Föcking, M., Dicker, P., Dunn, M. J., & Cotter, D. R. (2010). PROTEOMIC ANALYSIS OF THE BASIC SUB-PROTEOME (PH 6-11) IN THE HIPPOCAMPUS IN SCHIZOPHRENIA AND BIPOLAR AFFECTIVE DISORDER. Poster session presented at the meeting of Schizophrenia Research. Elsevier BV.
2008 Schubert, K. O., Foecking, M., Prehn, J. H., & Cotter, D. R. (2008). Differential hippocampal expression of proteins associated with NMDA receptor functioning in schizophrenia. Poster session presented at the meeting of RCSI Research Day. Dublin, Ireland. 2008 Schubert, K. O., Foecking, M., Dicker, P., Hudson, L., Dunn, M. J., & Cotter, D. (2008). Proteomic and western blot analysis of hippocampal subregions in schizophrenia and bipolar disorder.. Poster session presented at the meeting of The Schizophrenia International Research Society Conference. Venice, Italy. 2002 Schubert, K. O., Schnell, O., Zhi, Q., Kirsch, M., Hofmann, H. D., & Naumann, T. (2002). Protective effects of endogenous ciliary neurotrophic factor on axotomized GABAergic forebrain neurons. Poster session presented at the meeting of 5th European Meeting on Glial Cell Function in Health and Disease. Rome, Italy. 2002 Schubert, K. O., Schnell, O., Zhi, Q., Kirsch, M., Hoffmann, H. D., & Naumann, T. (2002). Endogenous ciliary neurotrophic factor (CNTF) and leukemia inhibitory factor (LIF) differentially affect axotomized basal ferebrain neurons. Poster session presented at the meeting of 3rd Forum of European Neuroscience. Paris, France. -
Theses
Year Citation 2014 Schubert, K. O. (2014). Effects of Schizophrenia, bipolar disorder, and haloperidol on the hippocampus: a proteomic approach. (PhD Thesis, Royal College of Surgeons in Ireland).
PhD funding: 2008-2014:
Clinician Scientist Fellowship, Molecular Medicine Ireland (MMI) Administered through RCSI, Ireland - EUR 180,000 (AUD 262,800)
Post-PhD funding:
2014:
RANZCP SA local branch research grant for undergraduate projects - AUD 2,500. Procter L, Stacey D, Schubert KO, Clark SR, Baune BT
2016:
Investigator Initiated Project (Industry Collaboration, Lundbeck): Trajecotories of Response to Abilify Maintena Study (TRAMS) – AUD 140.000 Baune BT, Clark SR, Schubert KO, Watson D.
RANZCP Research and Education Foundation Grant - AUD 10,000. Title: Developing blood biomarkers for long-term cognitive deficits in people with Major Depressive Disorder (MDD): Schubert KO
National Blood Authority Australia, National Blood Sector Research and Development Pilot Project Grant - AUD 139,000. Title: Preventive total dose of intravenous iron in pregnancy and beyond: Froessler B, Hodyl N, Stark M, Dekker G, Schubert KO
Society for Mental Health Research (SMHR) Early Career Researcher Project Grant - AUD 20,000. Title: Genomic and Proteomic validation of a gene expression module associated with poor response to lithium in Bipolar Affective Disorder: Schubert KO
Teaching
Undergraduate Programmes
MBBS Year 4 Clinical Psychiatry: introductury lectures (psychosis, psychopathology); exam-preparation tutorials; examiner for end-of-rotation examinations; preceptor for student placements at Lyell McEwin Hospital |
MBBS Year 5: examiner end-of-year examinations |
Faculty of Health Sciences Elective Course "Fundamentals of Biological Psychiatry": topic lectures - "clinical overview psychosis, mood disorder, anxiety disorders"; "biomarker research in psychiatry" |
Graduate Programmes
South Australian Psychiatric Training Committee (SAPTC): Seminars "First Episode Psychosis, Clinical Overview"; "Neurobiology of Depression and Medical Co-Morbidity" |
The Adelaide Pre-vocational Psychiatry Program (TAPPP): Seminar "Psychosis" |
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2019 Principal Supervisor Exploring The Relationship between Electroencephalography Aperiodic Slope, Neuroinflammation, Cognition and Function in Posttraumatic Stress Disorder Doctor of Philosophy Doctorate Full Time Mr Kai Tit Tan 2019 Co-Supervisor Analysis of symptomatic and biological changes in Major Depressive Disorder related to co-administered antidepressant and anti-inflammatory treatment Doctor of Philosophy Doctorate Part Time Miss Emma Karen Sampson 2018 Principal Supervisor Investigation into the Relationship Between Mental Health, Genetics and Health Outcomes in Chronic and Terminal Lung Disease Doctor of Philosophy Doctorate Part Time Mrs Debra Gaye Sandford -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2018 Co-Supervisor Genetic Predictors of Response to Pharmacotherapy in Patients with Mood Disorders: Steps on the Path to Personalised Psychiatry Doctor of Philosophy Doctorate Full Time Dr Azmeraw Tayelgn Amare
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Board Memberships
Date Role Board name Institution name Country 2015 - ongoing Board Member Human Brain Protein Project (HBPP), Scientific Board Human Brain Protein Project (HBPP) 2013 - ongoing Member Board of Examiners for Year 4/5 MBBS School of Medicine, The University of Adelaide -
Committee Memberships
Date Role Committee Institution Country 2016 - ongoing Advisory Board Member Youth Mental Health Services Expert Advisory Group SA Health 2015 - ongoing Member Early Career Psychiatrists Committee, 17th WPA World Congress of Psychiatry, Berlin, 2017 World Psychiatric Association 2014 - 2015 Member 2014 SMHR Conference - Local Organising Committee Society for Mental Health Research Australia 2014 - 2014 Co-Chair 2014 SMHR Conference - Social Committee Society for Mental Health Research Australia 2014 - 2014 Member 2014 SMHR Conference - Scientific Committee Society for Mental Health Research Australia 2013 - ongoing Member Year 4/5 MBBS Course Committee The University of Adelaide, School of Medicine Australia -
Memberships
Date Role Membership Country 2014 - ongoing Member Australian Early Psychosis Research Network Australia 2013 - ongoing Member Fellowship of the Royal Australian and New Zealand College of Psychiatrists Australia 2013 - ongoing Member Society for Mental Health Research (SMHR) Australia 2013 - ongoing Member Royal College of Psychiatrists United Kingdom 2013 - ongoing Member Northern Adelaide Local Health Network - The University of Adelaide Liaison Committee Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2016 - ongoing Board Member Irish Journal of Psychological Medicine
Connect With Me
External Profiles