Azmeraw Amare

Azmeraw Amare
Higher Degree by Research Candidate
Adelaide Medical School
Faculty of Health and Medical Sciences

Azmeraw T. Amare is a Clinical Epidemiologist and data scientist interested in precision medicine, the pharmacogenomics of antidepressants (SSRIs) & mood stabilizers (lithium), translational medicine and also in global health.

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External Profiles

Azmeraw Amare

Azmeraw T. Amare is a Clinical Epidemiologist and data scientist interested in precision medicine, the pharmacogenomics of antidepressants (SSRIs) & mood stabilizers (lithium), translational medicine and also in global health.

In my research, I apply novel and innovative bioinformatic techniques to identify predictors of response to treatment in psychiatric patients. I am particularly interested in the development of multivariable diagnostic or prognostic algorithms (tools) that can integrate individual’s genomic information with other predictors (e.g. omics pillars (including genomics, epigenomes, proteomics, metabolomics and microbiomes), neuroimaging and clinical characteristics) to finally predict therapeutic outcomes.

Currently, we assess the polygenic predictors of treatment response to antidepressants (SSRIs) and mood stabilizers (lithium) in patients with mood disorders. This project is being conducted in collaboration with international consortia, including the International SSRI Pharmacogenomics Consortium (ISPC), the International Consortium on Lithium Genetics (ConLi+Gen) and the National Institute of Mental Health (NIMH).

Appointments

Date Position Institution name
2015 - 2018 PhD candidate University of Adelaide

Awards and Achievements

Date Type Title Institution Name Amount
2017 - 2017 2017 World congress of psychiatry Young Fellowship Programme World Psychiatric Association
2015 - 2009 Adelaide Scholarship International (ASI) University of Adelaide
2014 19th summer institute in statistical genetics courses in Seattle University of Washington
2012 - 2014 CPE-SHARE research institute, University Medical center Groningen University of Groningen
2011 - 2017 CIUF-CUD Scholarship for postgraduate Study Belgium University Commission for Development (CIUF-CUD)
2006 Top student and gold medal among 2006 graduates in the faculty of public health Hawassa University

Education

Date Institution name Country Title
2015 University of Adelaide Australia PhD in Medicine
2014 - 2014 University of Groningen, Groningen Netherlands Master of Science in Clinical and Psychosocial Epidemiology (Research master)
2011 - 2012 Université Libre de Bruxelles, Brussels Belgium Master in research methodology

Certifications

Date Title Institution name Country
2014 19th Summer Institute in Statistical Genetics University of Washington, Seattle United States

Research Interests

Epidemiology, Genetics, Genomics, Pharmacogenomics, Psychiatry

Journals

Year Citation
2017 Amare, A., Schubert, K., Klingler-Hoffmann, M., Cohen-Woods, S. & Baune, B. (2017). The genetic overlap between mood disorders and cardiometabolic diseases: A systematic review of genome wide and candidate gene studies. Translational Psychiatry, 7, 1, -. 10.1038/tp.2016.261
2017 Nolte, I., Munoz, M., Tragante, V., Amare, A., Jansen, R., Vaez, A. ... Minassian, A. (2017). Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications, 8, -. 10.1038/ncomms15805
2017 Direk, N., Williams, S., Smith, J., Ripke, S., Air, T., Amare, A. ... Dunn, E. (2017). An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biological Psychiatry, 82, 5, 322-329. 10.1016/j.biopsych.2016.11.013
2017 Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A. ... Minassian, A. (2017). Genetic loci associated with heart rate variability and their effects on cardiac disease risk (vol 8, pg 15805, 2017). NATURE COMMUNICATIONS, 8, -. 10.1038/ncomms16140
2016 GBF 2015 Maternal Mortality Collaborators, , Wang, H., Amare, A., Hancock, J., Lalloo, R., Melaku, Y. & Tessema, G. (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388, 10053, 1725-1774. 10.1016/S0140-6736(16)31575-6
2016 GBF 2015 Maternal Mortality Collaborators, , Kassebaum, N., Amare, A., Ciobanu, L., Hancock, J., Lalloo, R. ... Tessema, G. (2016). Global, regional, and national levels of maternal mortality, 1990–2015 : a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388, 10053, 1775-1812. 10.1016/S0140-6736(16)31470-2
2016 Lim, S., Allen, K., Bhutta, Z., Dandona, L., Forouzanfar, M., Fullman, N. ... Wang, H. (2016). Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet, 388, 10053, 1813-1850. 10.1016/S0140-6736(16)31467-2

Book Chapters

Year Citation
2016 Amare, A., Schubert, & Baune, (2016). Genetic Overlap Between Depression and Cardiometabolic Disorders. In Baune & Tully (Eds.), Cardiovascular Diseases and Depression Treatment and Prevention in Psychocardiology (pp. 235-255). Switzerland: Springer.

Conference Items

Year Citation
2015 Amare, A. T., Nigatu, Y. T., Hsu, Y. -. H., Lahti, J., Alizadeh, B. Z. & Snieder, H. (2015). A bivariate Genome Wide Association Study (GWAS) of depressive symptoms and lipid levels has identified pleiotropic gene loci. Joint Meeting of the 20th Biennial Meeting of the International-Society-for-Developmental-Neuroscience / 5th Annual NeuroDevNet Brain Development Conference. Montreal, CANADA. 10.1016/j.ijdevneu.2015.04.305
Phone
83137438
Campus
North Terrace
Building
Adelaide Health and Medical Sciences Building
Room Number
WS7062.37
Org Unit
Health and Medical Sciences Faculty Office

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