Mr Nathan Beu

School of Pharmacy and Biomedical Sciences

College of Health

Available For Media Comment.


I am a methodologist, theoretician, cognitive neuroscientist, and experimental psychologist in the Cognitive Neural Sciences Lab of the School of Psychology and the Cognition, Ageing, and Neurodegenerative Disease laboratory in the School of Pharmacy and Biomedical Sciences. I am currently working on a project investigating the nature of Parkinson's disease and Traumatic Brain Injuries, and the utility of genomic and cognitive information to better predict, diagnose, and treat them, and on a project that maps latent structure of cognitive and motor abilities across the lifespan and the genetic involvement in their developmental processes and changes in later life.
 
I am interested in the neurobiological substrate of the psychological mechanisms involved in higher-order cognition, intelligence, and motor control (particularly the neurogenetics and frontal cortico-basal ganglia pathways involved in their concatenation). To do this, I take a model-based systems neuroscience approach, testing theoretical neural networks that might support these functions using converging evidence from traditional individual differences methods, computational and mathematical models, genotyping, EEG and other imaging methods, neurostimulation techniques, and behavioural testing. The purpose of this approach is to generate causal accounts of disturbances to, and lifespan fluctuations in, various cognitive and executive abilities required for goal-directed, adaptive behaviour.
 
The cognitive mechanisms that I target are those affected by psychiatric dysfunction, pathological degeneration, and ageing processes, such as response inhibition and cognitive control. My work primarily concentrates on reaction and response time and how they vary and fluctuate under different conditions, circumstances, and cognitive demands.
 
In addition to this, I am interested in identifying whether these mechanisms can be separated into discrete processes and how they concatenate using decomposition models of evidence accumulation. These models allow us to capture the distinct cognitive, neural, and motor processes involved in a single decision or a single response. In our lab, we develop, program, and validate novel conceptually, theoretically, and methodologically robust tasks that allow us to measure these processes individually and identify their utility, sensitivity, and specificity as markers of cognitive decline. We test existing models that yield parameters representing underlying cognitive processes that capture the dynamics of decisions, responses, and cognitive states, and map them onto imaging (EEG, MRI) and genetic information.
 
Using these approaches, dysfunction, disease, and degeneration can plausibly be detected using cognitive and behavioural assessments many years before other symptoms, such as psychomotor symptoms and memory impairments, manifest.
 
More broadly, my work has four themes: (1) the psychonomics and psychometrics of the individual differences in intelligence and various cognitive processes; (2) the underlying philosophies of experimental cognitive science and statistical inference, and the social impacts, influences, and implications of such work; (3) investigating potential targets for pharmaceutical, nutritional, technological, psychological, and physical interventions to enhance cognitive and motor functions in healthy individuals, and to offset the decline associated with disease states and ageing; and, (4) constructing formal models of pathology based on behavioural and cognitive assessment to improve the precision of medical diagnostics.
 
Central to my research, teaching, and supervision is my dedication to justice, equity, and ensuring access, representation, and diversity in both education and science. I am committed to improving the quality of science by promoting reproducible and open practices, principles I instantiate by sharing research code and data, preregistering study protocols, and supporting independent replication efforts, and through which, I aim to contribute to a more transparent, reliable, and equitable scientific community.

Cognitive Neural Sciences Laboratory  CNS Lab logo

In the Cognitive Neural Sciences Lab with Dr Irina Baetu, Prof Nicholas Burns, Lauren Heidenreich, Salvatore Russo, and Brittany Child, we are broadly interested in cognition and emotion and their neural underpinnings. We investigate how we learn from our experiences and how this learning guides our choices, as well as how we are able to exert cognitive control. These abilities are critical to our everyday functioning since making optimal decisions based on past experience ensures that we maximise positive outcomes and minimise aversive consequences. We study how these abilities change during ageing and in Parkinson’s disease. We are especially interested in discovering genetic variation that may help us preserve these abilities, as this might help the development of new treatments for cognitive decline. To do this, we are particularly interested in computational modelling and the neurogenetics of the basal ganglia.

We collaborate with:
Dr Lyndsey Collins-Praino
A/Prof Ahmed Moustafa
A/Prof Sarah Cohen-Woods
Dr Oren Griffiths

Date Position Institution name
2023 - ongoing Research Associate Adelaide University
2023 - ongoing Senior Tutor Adelaide University
2023 - ongoing Senior Marker and Assessor Adelaide University
2022 - 2023 Senior Postdoctoral Research Associate University of Newcastle
2021 - 2022 Postdoctoral Research Fellow Centre National de la Recherche Scientifique
2020 - 2020 Research Fellow Wellbeing and Recovery Research Institute
2019 - 2021 Research Associate University of Adelaide
2019 - 2020 Adjunct Research Associate PsychMed
2016 - 2022 Marker and Assessor University of Adelaide
2016 - 2020 Tutor University of Adelaide
2013 - 2019 Research Assistant University of Adelaide

Date Type Title Institution Name Country Amount
2013 Scholarship Undergraduate Research Scholarship University of Adelaide Australia -

Date Institution name Country Title
2016 - 2020 University of Adelaide Australia PhD in Medicine (Psychology)
2012 - 2015 University of Adelaide Australia Bachelor of Psychological Science (Hons, First Class)

Date Title Institution Country
2018 Investigating neural substrates of perception and cognition with large-scale data Allen Institute for Brain Science United States
2018 Computational Neuroscience Bernstein Center for Computational Neuroscience Berlin Germany
2018 Behavioural Genetics Broad Institute of MIT and Harvard United States

Year Citation
2025 Child, B., Beu, N., Saywell, I., da Silva, R., Collins-Praino, L., & Baetu, I. (2025). Cognitive function in different motor subtypes of Parkinson’s disease: A systematic review and multilevel meta-analysis. Cognitive Affective and Behavioral Neuroscience, 49 pages.
DOI
2023 Beu, N., Jayatilaka, A., Zahedi, M., Babar, A., Hartley, L., Lewinsmith, W., & Baetu, I. (2023). Falling for phishing attempts: An investigation of individual differences that are associated with behavior in a naturalistic phishing simulation. Computers and Security, 131, 1-11.
DOI Scopus19 WoS8
2023 Beu, N., Burns, N., & Baetu, I. (2023). Post-Error Slowing May Not Be Proactive: Electrophysiological evidence favours a disorienting account.
DOI
2022 Beu, N., Burns, N., & Baetu, I. (2022). Measurement of the response inhibition network in a brief battery of tasks: Introducing an assessment of reactive and proactive inhibition processes..
DOI
2022 Beu, N., Jayatilaka, A., Zahedi, M., Babar, A., Hartley, L., Lewinsmith, W., & Baetu, I. (2022). Falling for phishing attempts: An investigation of individual differences that are associated with behavior in a naturalistic phishing simulation.
DOI
2019 Beu, N. D., Burns, N. R., & Baetu, I. (2019). Polymorphisms in dopaminergic genes predict proactive processes of response inhibition. European Journal of Neuroscience, 49(9), 1069-1209.
DOI Scopus5 WoS5 Europe PMC5
2018 Baetu, I., Pitcher, J., Cohen-Woods, S., Lancer, B., Beu, N., Foreman, L., . . . Burns, N. (2018). Polymorphisms that affect GABA neurotransmission predict processing of aversive prediction errors in humans. NeuroImage, 176, 176-192.
DOI Scopus4 WoS5 Europe PMC4

Year Citation
2023 Karayanidis, F., Johnson, J., Ware, N., Johnson, S., Low, K., Soman, S., . . . Fabiani, M. (2023). ASSOCIATION BETWEEN CEREBRAL ARTERIAL ELASTICITY, CARDIOVASCULAR RISK AND COGNITION IN HEALTHY OLDER ADULTS. In PSYCHOPHYSIOLOGY Vol. 60 (pp. S48). LA, New Orleans: WILEY.
2022 Neau, M., Santos, P., Bosser, A. G., Beu, N., & Buche, C. (2022). Commonsense Reasoning for Identifying and Understanding the Implicit Need of Help and Synthesizing Assistive Actions. In A. Martin, K. Hinkelmann, H. -G. Fill, A. Gerber, D. Lenat, R. Stolle, & F. van Harmelen (Eds.), CEUR Workshop Proceedings Vol. 3121. California, USA: RWTH Aachen.

Year Citation
2018 Beu, N., Burns, N., & Baetu, I. (2018). Polymorphisms in dopaminergic genes predict proactive inhibition in a Go/No Go task. Poster session presented at the meeting of BEHAVIOR GENETICS. MA, Boston: SPRINGER.
2018 Beu, N., Burns, N., & Baetu, I. (2018). Polymorphisms in dopaminergic genes predict proactive inhibition in a Go/No-Go task. Poster session presented at the meeting of Conference programme: 48th Behavior Genetics Annual Meeting 2018. Cambridge, USA: Behavior Genetics Association.
2018 Beu, N. D., Burns, N. R., & Baetu, I. (2018). Polymorphisms in dopaminergic genes predict proactive inhibition in a Go/No-Go task. Poster session presented at the meeting of Forum for European Neuroscience Societies Forum of Neuroscience. Berlin, Germany.
2016 Beu, N. D., Burns, N. R., & Baetu, I. (2016). tDCS differentially modulates response inhibition processes disturbed by disease. Poster session presented at the meeting of Florey Postgraduate Conference. Adelaide, Australia.

Year Citation
2025 Sghirripa, S., Beu, N., Burns, N., Collins-Praino, L., Cohen-Woods, S., Jenkinson, M., & Baetu, I. (2025). Cognitive Reserve Buffers the Impact of Traumatic Events and Post-Traumatic Stress Symptoms on Mid- to Late-Life Cognitive Performance.
DOI

Level 4 (Honours)

Research Project & Thesis Assessor (2021 - Ongoing)

Level 3

Doing Research in Psychology: Advanced (2024 - Ongoing)
Individual Differences, Personality, and Assessment (2017 - 2020)
Learning and Behaviour (2016 - 2018)
Health and Lifespan Development Psychology (2016)

Level 2

Doing Research in Psychology (2019 - Ongoing)
Foundations of Health and Lifespan Development Psychology (2016)
Foundations of Perception and Cognition (2019)

Level 1

Psychology 1A (2016 - 2020)

Date Role Research Topic Program Degree Type Student Load Student Name
2024 External Supervisor An Exploration of the Role of Working Memory in Associative Learning Doctor of Philosophy Doctorate Part Time Miss Brittany Dorothy Amelia Child
2024 External Supervisor An Exploration of the Role of Working Memory in Associative Learning Doctor of Philosophy Doctorate Part Time Miss Brittany Dorothy Amelia Child

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2024 - ongoing External Supervisor An Exploration of the Role of Working Memory in Associative Learning University of Adelaide Doctor of Philosophy Doctorate Part Time Brittany Child

Date Role Committee Institution Country
2017 - 2019 Director Adelaide Postgraduate Student Association University of Adelaide Australia
2017 - 2019 Board Member Health Sciences Postgraduate Association University of Adelaide Australia
2015 - 2019 Representative School Committee University of Adelaide Australia

Date Role Membership Country
2018 - ongoing Member Behavior Genetics Association United States
2017 - ongoing Member Australasian Cognitive Neuroscience Society Australia
2017 - ongoing Co-Chair Brain and Cognition Group Australia
2017 - ongoing Member EEG Club Australia

Date Topic Presented at Institution Country
2018 - 2018 Age moderates the genetic effect of why we make simple errors and how we correct them The Laboratory of Neural Computation and Cognition Carney Institute for Brain Science, Brown University United States
2018 - 2018 Limitations and new directions for investigating response inhibition The Laboratory of Neural Computation and Cognition Carney Institute for Brain Science, Brown University United States

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