Lyndsey Collins-Praino

Associate Professor Lyndsey Collins-Praino

Associate Professor

School of Biomedicine

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD, but is currently at capacity - email supervisor to discuss availability.


Dr Lyndsey Collins-Praino holds a PhD in behavioral neuroscience. Her research focuses on the pathophysiological mechanisms underlying cognitive decline in healthy aging and in neurodegenerative diseases, including Alzheimer's and Parkinson's disease. She is particularly interested in the role of inflammation in this process. Her research has appeared in a variety of high-quality, peer-reviewed journals, and she has presented it at both national and international conferences. Lyndsey is the recipient of numerous prestigious fellowships, honours and awards for the novelty, quality and interest of this work, including a 2016 South Australian Young Tall Poppy award. Her research can be seen featured in multiple media outlets..

In addition to her research background, Lyndsey has significant teaching experience. She is co-convenor of the Neuroscience major in the Bachelor of Health and Medical Sciences, and teaches neuroanatomy and neuroscience courses to nursing, medical and health sciences students. Her commitment to teaching has been recognized by her receipt of the Executive Dean's Award for Teaching Excellence (2015) and the STEM Educator of the Year Award at the 2016 SA Science Excellence Awards.

Lyndsey is also heavily involved in neuroscience outreach in the local community. She has a strong commitment to making neuroscience content accessible and fun to children and young adults in the community, particularly to members of groups who are traditionally under-represented in the field. Lyndsey is the founder and organiser of the Kids Navigate Neuroscience event, held annually during National Science Week, and generously supported by a National Science Week grant. She is Treasurer of the National Science Week Committee (SA) and a member of the Inspiring South Australia Steering Group. She is also involved in raising community awareness of Parkinson's Disease, and volunteers as a speaker for Parkinson's SA.

I am the Head of the Cognition, Ageing and Neurodegenerative Disease laboratory (CANDL). Within CANDL, our research utilises an innovative "dish to deathbed" approach to identify novel predictors of the risk/rate of cognitive decline both in healthy ageing and in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. We are particularly interested on the role of neuroinflammation in this process.  

Currently, there are a number of projects ongoing. Some of these include

1. Investigation of whether targeting aberrant neuroinflammation can improve functional outcomes and slow dopamine neuron degeneration in pre-clinical models of Parkinson's disease.

2. Identification of novel methods to prevent the spread of pathological proteins in neurodegenerative disease.

3. Investigation of whether growth factor administration is able to prevent neurodegeneration and reduce chronic inflammation following traumatic brain injury.

4. Use of novel genomic analyses and cognitive data to predict risk and rate of cognitive decline in healthy ageing and Parkinson's disease.

5. Investigation of whether a neuroinflammatory signature is predictive of conversion to dementia in Parkinson's disease.

6. Assessment of the role of microglia in pathological transmission of alpha synuclein.

7. Use of cognitive training to improve cognitive function in Parkinson's disease.

8. Tracking the evolution of parkinsonian like-pathology following traumatic brain injury.

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  • Appointments

    Date Position Institution name
    2020 Associate Professor University of Adelaide
    2017 - 2019 Senior Lecturer, Anatomy and Pathology University of Adelaide
    2014 - 2016 Lecturer University of Adelaide
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2016 Award Early Career STEM Educator of the Year (Tertiary Teaching)
    2016 Award Executive Dean's Award for Teaching Excellence
    2016 Fellowship International Neurotrauma Symposium travel fellowship
    2016 Award South Australian Young Tall Poppy (Finalist, Tall Poppy of the Year)
    2015 Award Unsung euro of South Australian Science, Finalist
    2012 Fellowship Society for Neuroscience/Japanese Neuroscience Society Travel Award
    2012 Fellowship Alzheimer’s Disease International Conference travel fellowship
    2012 Award Henry Taub Award for Best Poster Presentation Columbia University Medical Centre United States
    2012 Fellowship NIA Butler-Williams Scholar
    2010 Award Outstanding Scientific Presentation University of Connecticut Health Center United States
    2010 Award Tieman Research Prize NEURON Conference
    2010 Fellowship Society for Neuroscience Graduate Student Travel Award
    2010 Fellowship International Basal Ganglia Society travel fellowship
    2006 Award Excellence in Neuroscience University of Scranton United States
  • Language Competencies

    Language Competency
    English Can read, write, speak, understand spoken and peer review
    Italian Can read, write, speak and understand spoken
  • Research Interests

Since 2014, I have received over $1.5 million in competitive research funding. Funding bodies include the Australian Research Council (ARC), Neurosurgical Research Foundation, James and Diana Ramsay Foundation, Brain Foundation, the Australia-Japan Foundation, Perpetual IMPACT Philanthropy Application Program and Adelaide Research and Innovation.

 

 

Prior to coming to the University of Adelaide, I taught neuroscience, psychology and anatomy courses at the University of Connecticut (Storrs, CT, USA), Fairfield University (Fairfield, CT, USA) and Eastern Connecticut State University (Willimantic, CT, USA).

At the University of Adelaide, I currently teach into a number of courses in the Bachelors of Health and Medical Sciences, including:

  • Foundations of Human Neuroanatomy (Coordinator)
  • Essentials of Neuroscience (Co-Coordinator)
  • Neurological Diseases
  • Essential Understanding of Disease and Treatment
  • Ethics, Science and Society
  • Exercise, Movement and Cognition

In addition to my teaching duties in the Bachelor of Health and Medical Sciences program, I provide a large portion of neuroanatomy content across Years 1-3 of the MBBS program.

I am Co-Convenor of the Neuroscience major in the Bachelor of Health and Medical Science program.

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  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2021 Principal Supervisor The Role of the Substantia Nigra in predicting longitudinal non-motor changes in Parkinson's Disease Doctor of Philosophy Doctorate Full Time Mr Benjamin Paul Ellul
    2021 Co-Supervisor Understanding the mechanisms of chemotherapy-induced cognitive impairment with a focus on neuroinflammation Doctor of Philosophy Doctorate Full Time Miss Olivia Jane Haller
    2021 Co-Supervisor Mapping the spread of toxic tau following traumatic brain injury to develop new biomarkers to identify those at risk of later developing dementia Master of Philosophy (Medical Science) Master Full Time Miss Eleanor Rose Bowley-Schubert
    2021 Principal Supervisor Assessing the role of traumatic brain injury in the spread of alpha synuclein in Parkinson’s Disease Master of Philosophy (Medical Science) Master Full Time Ms Samantha Elizabeth Edwards
    2021 Principal Supervisor Chemobrain impact and remediation: a focus on the paediatric patient Doctor of Philosophy Doctorate Full Time Miss Ines Semendric
    2021 Co-Supervisor Exploring the Building Blocks of Human Associative Learning Using Electroencephalography Doctor of Philosophy Doctorate Full Time Ms Lauren Mary Heidenreich
    2021 Principal Supervisor “Utility of Inflammatory Biomarkers to Predict Brainstem Imaging Changes in Parkinson’s Disease and TBI” Doctor of Philosophy Doctorate Full Time Mr Angus McNamara
    2021 Principal Supervisor Nanoparticle based strategies for the treatment of Parkinson's Disease: opportunities and challenges Doctor of Philosophy Doctorate Full Time Miss Laura May Carr
    2020 Co-Supervisor The Role of Neuroinflammation in Delayed Neurodegeneration following Ischemic Stroke Doctor of Philosophy Doctorate Full Time Miss Shannon Mikayla Stuckey
    2020 Co-Supervisor The role of neuroinflammation in mediating cognitive deficits following traumatic spinal cord injury: Can Fyn kinase inhibition break the link? Doctor of Philosophy Doctorate Full Time Miss Kavi Sivasankar
    2020 Principal Supervisor Decision making under threat Master of Philosophy (Medical Science) Master Full Time Mr Manuel Salazar
    2020 Co-Supervisor Potential Role of Aquaporin Channels in the Propagation of Extracellular Tau in Alzheimer's Disease Doctor of Philosophy Doctorate Full Time Mr Zein Alabedyn Amro
    2019 Principal Supervisor Mechanisms by which Neuroinflammation mediates the development and progression of Parkinsons' Disease Doctor of Philosophy under a Jointly-awarded Degree Agreement with Doctorate Full Time Miss Ing Chee Wee
    2019 Co-Supervisor Blood-Brain Barrier Changes in Healthy Ageing and Disease Doctor of Philosophy Doctorate Full Time Miss Isabella Megan Bilecki
    2019 Co-Supervisor An Exploration of the Role of Working Memory in Associative Learning Doctor of Philosophy Doctorate Full Time Miss Brittany Dorothy Amelia Child
    2017 Principal Supervisor Targeting Cognitive Impairment in Parkinson’s Disease: Novel Pharmacological and Non-Pharmacological Approaches Doctor of Philosophy Doctorate Full Time Miss Bianca Laura Guglietti
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2019 - 2019 Co-Supervisor Peripheral-to-Central Neuroimmune Communication and the Sun: Implications for Addiction and Neurodegenerative Disease Pathology Master of Philosophy (Medical Science) Master Full Time Ms Krystal Lee Iacopetta
    2015 - 2019 Principal Supervisor From Trauma to Neurodegeneration: A One-Year Time Progression of Functional Impairments and its Associated Neuropathological Link Following Varied Severity of Experimental Diffuse Traumatic Brain Injury Doctor of Philosophy Doctorate Full Time Miss Alina Arulsamy
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  • Committee Memberships

    Date Role Committee Institution Country
    2016 - ongoing Member School of Medicine (SOM) Early/Middle Career Researcher Committee University of Adelaide
    2016 - ongoing Treasurer National Science Week Committee (South Australia)
    2016 - ongoing Member Inspiring South Australia Steering Group
    2015 - ongoing Chair Year 1 MBBS Committee University of Adelaide
    2015 - ongoing Member MBBS Assessment Committee University of Adelaide
    2015 - ongoing Member Low-Risk Human Research Ethics Committee University of Adelaide
    2015 - ongoing Member MBBS Curriculum Committee Member
    2015 - 2015 Member School of Medical Sciences Learning and Teaching Committee Member University of Adelaide
    2015 - 2015 Member School of Medical Sciences Seminar Committee University of Adelaide
  • Memberships

    Date Role Membership Country
    2016 - ongoing Australasian Cognitive Neuroscience Society
    2016 - ongoing International Neurotrauma Society
    2015 - ongoing International Society for Neurochemistry
    2015 - ongoing Australasian Neuroscience Society
    2006 - ongoing Member Society for Neuroscience
    2006 - ongoing Member International Basal Ganglia Society
  • Offices Held

    Date Office Name Institution Country
    2016 - ongoing Co-convenor, Neuroscience Major University of Adelaide
    2015 - ongoing Year 1 Convenor, MBBS Program University of Adelaide
  • Position: Associate Professor
  • Phone: 83135488
  • Email: lyndsey.collins-praino@adelaide.edu.au
  • Campus: North Terrace
  • Building: Helen Mayo North, floor 2
  • Room: N2 12
  • Org Unit: Medical Sciences

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