School of Biomedicine
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD, but is currently at capacity - email supervisor to discuss availability.
Dr Lyndsey Collins-Praino holds a PhD in behavioral neuroscience. Her research focuses on the pathophysiological mechanisms underlying cognitive decline in healthy aging and in neurodegenerative diseases, including Alzheimer's and Parkinson's disease. She is particularly interested in the role of inflammation in this process. Her research has appeared in a variety of high-quality, peer-reviewed journals, and she has presented it at both national and international conferences. Lyndsey is the recipient of numerous prestigious fellowships, honours and awards for the novelty, quality and interest of this work, including a 2016 South Australian Young Tall Poppy award. Her research can be seen featured in multiple media outlets..
In addition to her research background, Lyndsey has significant teaching experience. She is co-convenor of the Neuroscience major in the Bachelor of Health and Medical Sciences, and teaches neuroanatomy and neuroscience courses to nursing, medical and health sciences students. Her commitment to teaching has been recognized by her receipt of the Executive Dean's Award for Teaching Excellence (2015) and the STEM Educator of the Year Award at the 2016 SA Science Excellence Awards.
Lyndsey is also heavily involved in neuroscience outreach in the local community. She has a strong commitment to making neuroscience content accessible and fun to children and young adults in the community, particularly to members of groups who are traditionally under-represented in the field. Lyndsey is the founder and organiser of the Kids Navigate Neuroscience event, held annually during National Science Week, and generously supported by a National Science Week grant. She is Treasurer of the National Science Week Committee (SA) and a member of the Inspiring South Australia Steering Group. She is also involved in raising community awareness of Parkinson's Disease, and volunteers as a speaker for Parkinson's SA.
- My Research
- Grants and Funding
- Professional Activities
I am the Head of the Cognition, Ageing and Neurodegenerative Disease laboratory (CANDL). Within CANDL, our research utilises an innovative "dish to deathbed" approach to identify novel predictors of the risk/rate of cognitive decline both in healthy ageing and in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. We are particularly interested on the role of neuroinflammation in this process.
Currently, there are a number of projects ongoing. Some of these include
1. Investigation of whether targeting aberrant neuroinflammation can improve functional outcomes and slow dopamine neuron degeneration in pre-clinical models of Parkinson's disease.
2. Identification of novel methods to prevent the spread of pathological proteins in neurodegenerative disease.
3. Investigation of whether growth factor administration is able to prevent neurodegeneration and reduce chronic inflammation following traumatic brain injury.
4. Use of novel genomic analyses and cognitive data to predict risk and rate of cognitive decline in healthy ageing and Parkinson's disease.
5. Investigation of whether a neuroinflammatory signature is predictive of conversion to dementia in Parkinson's disease.
6. Assessment of the role of microglia in pathological transmission of alpha synuclein.
7. Use of cognitive training to improve cognitive function in Parkinson's disease.
8. Tracking the evolution of parkinsonian like-pathology following traumatic brain injury.
Date Position Institution name 2020 Associate Professor University of Adelaide 2017 - 2019 Senior Lecturer, Anatomy and Pathology University of Adelaide 2014 - 2016 Lecturer University of Adelaide
Awards and Achievements
Date Type Title Institution Name Country Amount 2016 Award Early Career STEM Educator of the Year (Tertiary Teaching) — — — 2016 Award Executive Dean's Award for Teaching Excellence — — — 2016 Fellowship International Neurotrauma Symposium travel fellowship — — — 2016 Award South Australian Young Tall Poppy (Finalist, Tall Poppy of the Year) — — — 2015 Award Unsung euro of South Australian Science, Finalist — — — 2012 Fellowship Society for Neuroscience/Japanese Neuroscience Society Travel Award — — — 2012 Fellowship Alzheimer’s Disease International Conference travel fellowship — — — 2012 Award Henry Taub Award for Best Poster Presentation Columbia University Medical Centre United States — 2012 Fellowship NIA Butler-Williams Scholar — — — 2010 Award Outstanding Scientific Presentation University of Connecticut Health Center United States — 2010 Award Tieman Research Prize NEURON Conference — — 2010 Fellowship Society for Neuroscience Graduate Student Travel Award — — — 2010 Fellowship International Basal Ganglia Society travel fellowship — — — 2006 Award Excellence in Neuroscience University of Scranton United States —
Language Competency English Can read, write, speak, understand spoken and peer review Italian Can read, write, speak and understand spoken
Year Citation 2020 Foreman, L., Baetu, I., Rego, J., Moustafa, A., & Collins-Praino, L. (2020). Theories of compulsive drug use: A brief overview of learning and motivation processes. In A. Moustafa (Ed.), Cognitive, Clinical, and Neural Aspects of Drug Addiction (pp. 137-185). London, United Kingdom: Academic Press. 2014 Salamone, J., Podurgiel, S., Collins-Praino, L., & Correa, M. (2014). Physiological and behavioral assessment of tremor in rodents. In M. LeDoux (Ed.), Movement Disorders: Genetics and Models (2 ed., pp. 631-640). Elsevier.
Year Citation 2017 Collins-Praino, L., Burton, J., & Johnson, I. (2017). Integration of a novel three-dimensional teaching tool for undergraduate neuroanatomy: student opinions and learning outcomes.. In Journal of Anatomy Vol. 230 (pp. 358). Sussex, UK: Blackwell Publishing Inc.. 2015 Collins-Praino, L., Burton, J., & Johnson, I. (2015). Evaluation of the utility of an in-house three-dimensional teaching tool for undergraduate neuroanatomy. In Abstracts presented at the Australian and New Zealand Association of Clinical Anatomists (ANZACA) 11th annual meeting, “Anatomy in work and play,” 3rd to 5th December 2014, Queenstown, Otago, New Zealand, as published in Clinical Anatomy Vol. 28 (pp. 941). Queenstown, New Zealand: Wiley.
Year Citation 2019 Child, B. D., Baetu, I., Collins-Praino, L., & Burns, N. (2019). Reinforcement learning in Parkinson’s disease: Do motor symptoms predict performance?. Poster session presented at the meeting of 28th Annual Meeting of the International Behavioral Neuroscience Society. Cairns, Australia. 2019 Corrigan, F., Kaukas, L., Collins-Praino, L., & Holmes, J. (2019). EFFECT OF A MILD TRAUMATIC BRAIN INJURY DURING ADOLESCENCE ON EXECUTIVE FUNCTION IN ADULTHOOD. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Pittsburgh, PA: MARY ANN LIEBERT, INC. 2019 Child, B. D., Baetu, I., Collins-Praino, L., Salamon, J., & Burns, N. (2019). Reinforcement learning in Parkinson's disease: Do motor symptoms predict performance?. Poster session presented at the meeting of Florey Postgraduate Research Conference. Adelaide, Australia. 2018 Johnson, I., Collins-Praino, L., & Burton, J. (2018). They liked it, but did they learn anything?. Poster session presented at the meeting of Clinical Anatomy. Canberra, Australia: Wiley. 2016 Collins-Praino, L., Teng, J., Colton, H., Van den Heuvel, C., & Corrigan, F. (2016). INVESTIGATING THE COMPLEX RELATIONSHIP BETWEEN NEUROINFLAMMATION, NEURODEGENERATION AND LONG-TERM FUNCTIONAL OUTCOMES IN AN EXPERIMENTAL MODEL OF TRAUMATIC BRAIN INJURY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Cape Town, SOUTH AFRICA: MARY ANN LIEBERT, INC. 2016 Corrigan, F., & Vink, R. (2016). Toll like receptor 4 activation can be either detrimental or beneficial following mild repetitive traumatic brain injury depending on timing of activation. Poster session presented at the meeting of Abstracts of the 12th Symposium of the International Neurotrauma Society, as published in Journal of Neurotrauma. Cape Town, SOUTH AFRICA: Mary Ann Liebert.
2012 Collins-Praino, L., Scarmeas, N., Manly, J., Schupf, N., Noble, J., Provenzano, F., . . . Brickman, A. (2012). P3-193: White matter hyperintensities may mediate the relationship between inflammation and cognition in an elderly cohort. Poster session presented at the meeting of Alzheimer's & Dementia. Wiley.
Year Citation 2021 Semendric, I., Haller, O., George, R., Pollock, D., Whittaker, A., & Collins-Praino, L. (2021). Experience of the impact of chemobrain in childhood cancer survivors: a qualitative systematic review protocol. PROSPERO 2021 CRD42021240573. PROSPERO. 2021 Haller, O., Whittaker, A., George, R., Semendric, I., & Collins-Praino, L. (2021). Investigating the effects of anti-inflammatory agents in pre-clinical models of chemotherapy-induced cognitive impairment – a systematic review protocol. PROSPERO- registration no: CRD42021240789.
Since 2014, I have received over $1.5 million in competitive research funding. Funding bodies include the Australian Research Council (ARC), Neurosurgical Research Foundation, James and Diana Ramsay Foundation, Brain Foundation, the Australia-Japan Foundation, Perpetual IMPACT Philanthropy Application Program and Adelaide Research and Innovation.
Prior to coming to the University of Adelaide, I taught neuroscience, psychology and anatomy courses at the University of Connecticut (Storrs, CT, USA), Fairfield University (Fairfield, CT, USA) and Eastern Connecticut State University (Willimantic, CT, USA).
At the University of Adelaide, I currently teach into a number of courses in the Bachelors of Health and Medical Sciences, including:
- Foundations of Human Neuroanatomy (Coordinator)
- Essentials of Neuroscience (Co-Coordinator)
- Neurological Diseases
- Essential Understanding of Disease and Treatment
- Ethics, Science and Society
- Exercise, Movement and Cognition
In addition to my teaching duties in the Bachelor of Health and Medical Sciences program, I provide a large portion of neuroanatomy content across Years 1-3 of the MBBS program.
I am Co-Convenor of the Neuroscience major in the Bachelor of Health and Medical Science program.
Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2021 Principal Supervisor The Role of the Substantia Nigra in predicting longitudinal non-motor changes in Parkinson's Disease Doctor of Philosophy Doctorate Full Time Mr Benjamin Paul Ellul 2021 Co-Supervisor Understanding the mechanisms of chemotherapy-induced cognitive impairment with a focus on neuroinflammation Doctor of Philosophy Doctorate Full Time Miss Olivia Jane Haller 2021 Co-Supervisor Mapping the spread of toxic tau following traumatic brain injury to develop new biomarkers to identify those at risk of later developing dementia Master of Philosophy (Medical Science) Master Full Time Miss Eleanor Rose Bowley-Schubert 2021 Principal Supervisor Assessing the role of traumatic brain injury in the spread of alpha synuclein in Parkinson’s Disease Master of Philosophy (Medical Science) Master Full Time Ms Samantha Elizabeth Edwards 2021 Principal Supervisor Chemobrain impact and remediation: a focus on the paediatric patient Doctor of Philosophy Doctorate Full Time Miss Ines Semendric 2021 Co-Supervisor Exploring the Building Blocks of Human Associative Learning Using Electroencephalography Doctor of Philosophy Doctorate Full Time Ms Lauren Mary Heidenreich 2021 Principal Supervisor “Utility of Inflammatory Biomarkers to Predict Brainstem Imaging Changes in Parkinson’s Disease and TBI” Doctor of Philosophy Doctorate Full Time Mr Angus McNamara 2021 Principal Supervisor Nanoparticle based strategies for the treatment of Parkinson's Disease: opportunities and challenges Doctor of Philosophy Doctorate Full Time Miss Laura May Carr 2020 Co-Supervisor The Role of Neuroinflammation in Delayed Neurodegeneration following Ischemic Stroke Doctor of Philosophy Doctorate Full Time Miss Shannon Mikayla Stuckey 2020 Co-Supervisor The role of neuroinflammation in mediating cognitive deficits following traumatic spinal cord injury: Can Fyn kinase inhibition break the link? Doctor of Philosophy Doctorate Full Time Miss Kavi Sivasankar 2020 Principal Supervisor Decision making under threat Master of Philosophy (Medical Science) Master Full Time Mr Manuel Salazar 2020 Co-Supervisor Potential Role of Aquaporin Channels in the Propagation of Extracellular Tau in Alzheimer's Disease Doctor of Philosophy Doctorate Full Time Mr Zein Alabedyn Amro 2019 Principal Supervisor Mechanisms by which Neuroinflammation mediates the development and progression of Parkinsons' Disease Doctor of Philosophy under a Jointly-awarded Degree Agreement with Doctorate Full Time Miss Ing Chee Wee 2019 Co-Supervisor Blood-Brain Barrier Changes in Healthy Ageing and Disease Doctor of Philosophy Doctorate Full Time Miss Isabella Megan Bilecki 2019 Co-Supervisor An Exploration of the Role of Working Memory in Associative Learning Doctor of Philosophy Doctorate Full Time Miss Brittany Dorothy Amelia Child 2017 Principal Supervisor Targeting Cognitive Impairment in Parkinson’s Disease: Novel Pharmacological and Non-Pharmacological Approaches Doctor of Philosophy Doctorate Full Time Miss Bianca Laura Guglietti
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2019 - 2019 Co-Supervisor Peripheral-to-Central Neuroimmune Communication and the Sun: Implications for Addiction and Neurodegenerative Disease Pathology Master of Philosophy (Medical Science) Master Full Time Ms Krystal Lee Iacopetta 2015 - 2019 Principal Supervisor From Trauma to Neurodegeneration: A One-Year Time Progression of Functional Impairments and its Associated Neuropathological Link Following Varied Severity of Experimental Diffuse Traumatic Brain Injury Doctor of Philosophy Doctorate Full Time Miss Alina Arulsamy
Date Role Committee Institution Country 2016 - ongoing Member School of Medicine (SOM) Early/Middle Career Researcher Committee University of Adelaide — 2016 - ongoing Treasurer National Science Week Committee (South Australia) — — 2016 - ongoing Member Inspiring South Australia Steering Group — — 2015 - ongoing Chair Year 1 MBBS Committee University of Adelaide — 2015 - ongoing Member MBBS Assessment Committee University of Adelaide — 2015 - ongoing Member Low-Risk Human Research Ethics Committee University of Adelaide — 2015 - ongoing Member MBBS Curriculum Committee Member — — 2015 - 2015 Member School of Medical Sciences Learning and Teaching Committee Member University of Adelaide — 2015 - 2015 Member School of Medical Sciences Seminar Committee University of Adelaide —
Date Role Membership Country 2016 - ongoing — Australasian Cognitive Neuroscience Society — 2016 - ongoing — International Neurotrauma Society — 2015 - ongoing — International Society for Neurochemistry — 2015 - ongoing — Australasian Neuroscience Society — 2006 - ongoing Member Society for Neuroscience — 2006 - ongoing Member International Basal Ganglia Society —
Date Office Name Institution Country 2016 - ongoing Co-convenor, Neuroscience Major University of Adelaide — 2015 - ongoing Year 1 Convenor, MBBS Program University of Adelaide —
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