Mr Isaac Saywell

Grant-Funded Researcher (A)

School of Public Health

College of Health


Dr Isaac Saywell is an early-career Research Fellow in the Synthesis Science Division at JBI, Adelaide University. He has completed a PhD in Cognitive Neuroscience entitled "Resilience to neurodegeneration: the role of cognitive reserve in explaining Parkinson’s disease cognitive heterogeneity". Isaac has multiple years of academic and industry-related experience, with proficiency in research and teaching across several disciplines including neuroscience, psychology, health sciences, public health, evidence synthesis, and research methodology. 
 
In his current role at JBI, Isaac contributes to the development, conduct, and use of evidence synthesis methods. He is actively involved in methodological research focused on increasing understanding of effective evidence synthesis methodology and improving the quality of research workflows. Isaac is also responsible for the ongoing development and delivery of JBI teaching materials related to evidence synthesis and research, such as the Comprehensive Systematic Review Training Program, Scoping Review Workshop, and Use of Artificial Intelligence in Evidence Synthesis Workflows.  
 
Before working at JBI, Isaac worked on several projects related to healthy ageing, traumatic brain injury, and Parkinson's disease, where he led and assisted with research exploring individual differences in clinical outcomes using a combination of cognitive testing and magnetic resonance imaging. He was also responsible for managing a large magnetic resonance imaging database, tasked with preprocessing and organising healthy adult, traumatic brain injury and Parkinson's disease data obtained from multiple imaging modalities. Isaac's other roles throughout his doctoral studies consisted of teaching neuroscience, psychology, health sciences, and research methodology to undergraduate students. 
 
Isaac's research interests include meta-analysis, advanced statistical methods for systematic reviews, improving the systematic review workflow efficiency, and evidence synthesis methodology more broadly. He also has a keen interest in utilising cognitive assessments and neuroimaging to investigate individual differences in normal ageing and pathological circumstances, with the aim of improving outcomes for those affected by traumatic brain injuries and neurodegeneration. Beyond research, Isaac is committed to being an effective and supportive teacher who enhances students' learning experiences and fosters their intellectual growth.

Date Position Institution name
2025 - ongoing Research Fellow Adelaide University

Date Institution name Country Title
2022 - 2026 University of Adelaide Australia Doctor of Philosophy (PhD) - Cognitive Neuroscience
2021 - 2021 University of Adelaide Australia Honours Degree of Psychological Science (First Class)
2018 - 2020 University of Adelaide Australia Bachelor of Psychological Science

Year Citation
2026 Saywell, I., Sghirripa, S., Walls, A., Dwyer, A., Child, B., Salamon, J., . . . Baetu, I. (2026). Cognitive reserve proxies predict cognition and motor function beyond multimodal MRI brain measures in healthy adults. Biological Psychology, 209, 109327-1-109327-13.
DOI
2026 Child, B., Beu, N., Saywell, I., da Silva, R., Collins-Praino, L., & Baetu, I. (2026). Cognitive function in different motor subtypes of Parkinson's disease: A systematic review and multilevel meta-analysis.. Cogn Affect Behav Neurosci, 26(1), 218-266.
DOI Scopus1 WoS1 Europe PMC1
2025 Foreman, L., Child, B., Saywell, I., Collins-Praino, L., & Baetu, I. (2025). Cognitive reserve moderates the effect of COVID-19 on cognition: A systematic review and meta-analysis of individual participant data. Neuroscience and Biobehavioral Reviews, 171, 31 pages.
DOI Scopus6 WoS5 Europe PMC3
2024 Saywell, I., Foreman, L., Child, B., Phillips-Hughes, A. L., Collins-Praino, L., & Baetu, I. (2024). Influence of cognitive reserve on cognitive and motor function in α-synucleinopathies: A systematic review and multilevel meta-analysis. Neuroscience and Biobehavioral Reviews, 161, 28 pages.
DOI Scopus11 WoS10 Europe PMC7
2024 Child, B., Saywell, I., da Silva, R., Collins-Praino, L., & Baetu, I. (2024). Cognitive function in different motor subtypes of Parkinson's disease: A systematic review protocol.. Health Sci Rep, 7(5), e2092.
DOI Scopus5 WoS4 Europe PMC6
2023 Saywell, I., Child, B., Foreman, L., Collins‐Praino, L., & Baetu, I. (2023). Influence of cognitive reserve on cognitive and motor function in α‐synucleinopathies: A systematic review protocol. Annals of the New York Academy of Sciences, 1522(1), 15-23.
DOI Scopus3 WoS3 Europe PMC2

University of Adelaide:

Tutor and Lab Demonstrator for ANAT SC 2006: Foundations of Human Neuroanatomy (2023, 2024, 2025)

Tutor for ANAT SC 2110: The Neuroscience of Human Cognition and Behaviour (2024, 2025)

Tutor for HLTH SC 1001: Essentials of Neuroscience (2023, 2024)

Tutor and Marker for PSYCHOL 2005: Foundations of Health and Lifespan Development (2022)

Marker for PSYCHOL 1001: Psychology 1B (2023, 2024)

University of South Australia:

Tutor, Marker and Practical Demonstrator for HLTH 2026: Motor Control and Learning (2023, 2024, 2025)


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