APrf Mitchell Goldsworthy
Enterprise Fellow
School of Psychology
College of Education, Behavioural and Social Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
I am an Enterprise Fellow in Psychology, ARC Future Fellow, and Deputy Director of the Behaviour-Brain-Body Research Centre at Adelaide University. My research expertise spans human neuroscience and cognitive ageing and centres on two complementary research themes: the methodological and physiological factors that influence neuroplasticity induced by non-invasive brain stimulation in humans, and the neural mechanisms through which changes in brain function across the adult lifespan contribute to cognitive resilience or impairment in older age. Together, these research streams aim to advance our understanding of cognitive ageing and inform the development of novel strategies to non-invasively modulate brain function and build resilience to age-related cognitive decline.
I use a range of complementary research methods, including transcranial magnetic stimulation (TMS), transcranial electrical stimulation (tES), electroencephalography (EEG), magnetic resonance imaging (MRI), and behavioural assessment, to investigate the neural physiology underlying cognitive performance and ageing. Current projects of interest include:
Neural noise in human cognitive ageing and reserve
Age-related increases in neural noise degrade information transfer in the brain and lead to diminished cognitive function. Yet with cognitive reserve, some people are able to maintain healthy functioning well into their later years. This project aims to investigate the effects of neural noise on brain connectivity, cognitive performance and reserve, advancing breakthrough work on the neural physiology of healthy cognitive ageing and malleability of neural noise. This will be delivered by novel combinations of electrophysiology, neuroimaging and non-invasive brain stimulation. Benefits extend from developing neural markers for measuring cognitive reserve to new strategies for building resilience to age-related cognitive decline.
Aperiodic neural activity across time: prospects for optimising human cognition
The aperiodic signal that pervades human brain activity changes over the lifespan and explains individual differences in cognitive function. Yet, the physiological and behavioural impacts of aperiodic signal fluctuations over shorter time scales remain unclear. This project aims to investigate the effects of time-varying aperiodic neural activity on human cognitive performance, brain excitability and neuroplasticity. This will be delivered by a closed-loop approach, using brain signals recorded in real time to target momentary shifts in aperiodic activity and infer direct causal relationships. Benefits include a detailed mechanistic understanding of how dynamic fluctuations in aperiodic neural activity across time affect human behaviour.
| Date | Position | Institution name |
|---|---|---|
| 2026 - ongoing | Deputy Director, Behaviour-Brain-Body Research Centre | Adelaide University |
| 2026 - ongoing | Enterprise Fellow, ARC Future Fellow, Associate Research Professor | Adelaide University |
| 2024 - 2025 | Deputy Director, Behaviour-Brain-Body Research Centre | University of South Australia |
| 2024 - 2025 | ARC Future Fellow | University of South Australia |
| 2023 - 2025 | Enterprise Fellow, Psychology | University of South Australia |
| 2020 - 2023 | ARC DECRA Research Fellow, Senior Research Fellow | University of Adelaide |
| 2016 - 2019 | NHMRC–ARC Dementia Research Development Fellow | University of Adelaide |
| 2014 - 2015 | AADRF Postdoctoral Research Fellow | University of Adelaide |
| 2013 - 2013 | Postdoctoral Research Officer | University of Adelaide |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2010 - 2013 | University of Adelaide | Australia | PhD (Medicine) |
| 2009 - 2009 | University of Adelaide | Australia | Honours Degree of Bachelor of Science |
| 2006 - 2008 | University of Adelaide | Australia | Bachelor of Science (Biomedical Science) |
| Year | Citation |
|---|---|
| 2022 | Hussain, S., Price, G., McAndrew, M., Bose, A., Rodger, J., Hennessy, L. A., . . . McFarlane, A. (2022). REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (RTMS), ELECTROENCEPHALOGRAPHY (EEG) AND CONNECTOMES: A CLINICAL AND TECHNICAL UPDATE. In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY Vol. 56 (pp. 115-116). SAGE PUBLICATIONS LTD. |
| Year | Citation |
|---|---|
| 2023 | Arthurs, E., Goldsworthy, M., Sokolenko, E., Schubert, K. O., Tan, K. T., Bol, D., & Clark, S. (2023). Frontal Alpha Asymmetry as a Biomarker of Symptoms, Cognition, and Function in Mood Disorders. Poster session presented at the meeting of Society for Social and Affective Neuroscience. Adelaide. |
| 2022 | Tan, K. T., Lawrence, A., Lawrence-Wood, E., Edwards, S., Rogasch, N., Schubert, K. O., . . . McFarlane, A. (2022). TRAUMA HISTORY IS ASSOCIATED WITH A 1/F ELECTROENCEPHALOGRAPHY (EEG) SIGNATURE IN A MILITARY SAMPLE. Poster session presented at the meeting of AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY. SAGE PUBLICATIONS LTD. |
| Year | Citation |
|---|---|
| 2026 | Holden, M., Goldsworthy, M., Liao, W. -Y., Clark, S., Cline, C., Keller, C., . . . Rogasch, N. (2026). Characterising and Minimising Step and Filtering Artifacts in TMS-EEG Recordings. DOI |
| 2024 | Boda, M., Otieno, L., Smith, A., Goldsworthy, M., & Sidhu, S. (2024). Metaplastic neuromodulation via transcranial direct current stimulation has no effect on corticospinal excitability and neuromuscular fatigue. DOI |
| 2023 | Mellow, M., Dumuid, D., Olds, T., Stanford, T., Dorrian, J., Wade, A., . . . Smith, A. (2023). Cross-sectional associations between 24-hour time-use composition, grey matter volume and cognitive function in healthy older adults. DOI |
| 2021 | Smith, A., Wade, A., Olds, T., Dumuid, D., Breakspear, M., Laver, K., . . . Karayanidis, F. (2021). Optimising activity and diet compositions for dementia prevention: Protocol for the ACTIVate prospective longitudinal cohort study. DOI |
| 2020 | Van Dam, J., Goldsworthy, M. R., Hague, W. M., Coat, S., & Pitcher, J. B. (2020). Lower Morning Cortisol Secretion in Adolescents Born to Women with Gestational Diabetes Mellitus. |
My research has attracted more than $5 million in competitive research funding, with more than $3.3 million as lead/sole CI. This includes:
- ARC Discovery Project (CIA), 2026-2029
- ARC Future Fellowship (sole CI), 2024-2028
- NHMRC Boosting Dementia Research Grant (CIF), 2020-2024
- ARC Discovery Early Career Researcher Award (sole CI), 2020-2022
- Yulgilbar Postdoctoral Excellence Award (CIA), 2017
- NHMRC-ARC Dementia Research Development Fellowship (sole CI), 2016–2019
- Alzheimer’s Australia (AADRF) Project Grant (CIA), 2015
- AADRF Postdoctoral Research Fellowship (sole CI), 2014-2015
- German Academic Exchange Service (DAAD) Research Grant (sole CI), 2012
Courses I teach
- BEHL 1004 Psychology 1B (2025)
- BEHL 1004 Psychology 1B (2024)
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2026 | Principal Supervisor | Neural noise in human cognitive ageing and reserve | Doctor of Philosophy | Doctorate | Full Time | Ms Yaroslava Leonova |
| 2025 | Co-Supervisor | The Neural Correlates of Working Memory | Master of Philosophy (Medical Science) | Master | Full Time | Ms Anis Syatirah Mohammad Gadapi |
| 2025 | Co-Supervisor | Integrating EEG feature discovery and biophysical modelling to optimise TMS for working memory | Doctor of Philosophy | Doctorate | Full Time | Mr Thomas Eblinghaus |
| 2025 | Co-Supervisor | The Neural Correlates of Working Memory | Master of Philosophy | Master | Full Time | Ms Anis Syatirah Mohammad Gadapi |
| 2025 | Co-Supervisor | Neurophysiological indices of delirium: risk to recovery | Doctor of Philosophy | Doctorate | Full Time | Miss Jingxian Lin |
| 2025 | Co-Supervisor | Integrating EEG feature discovery and biophysical modelling to optimise TMS for working memory | - | Doctorate | Full Time | Mr Thomas Eblinghaus |
| 2025 | Co-Supervisor | Integrating EEG feature discovery and biophysical modelling to optimise TMS for working memory | Doctor of Philosophy | Doctorate | Full Time | Mr Thomas Eblinghaus |
| 2023 | Principal Supervisor | Neurophysiology of Cognitive Reserve and Working Memory in Ageing | Doctor of Philosophy | Doctorate | Full Time | Ms Victoria Prowse |
| 2023 | Principal Supervisor | Neurophysiology of Cognitive Reserve and Working Memory in Ageing | Doctor of Philosophy | Doctorate | Full Time | Ms Victoria Prowse |
| 2023 | Principal Supervisor | Neurophysiology of Cognitive Reserve and Working Memory in Ageing | Doctor of Philosophy | Doctorate | Part Time | Ms Victoria Prowse |
| 2022 | Co-Supervisor | The interaction between diet, physical activity and neuroplasticity in multiple sclerosis | Doctor of Philosophy | Doctorate | Full Time | Miss Madison Boda |
| 2022 | Co-Supervisor | The interaction between diet, physical activity and neuroplasticity in multiple sclerosis | - | Doctorate | Part Time | Miss Madison Boda |
| 2022 | Co-Supervisor | The interaction between diet, physical activity and neuroplasticity in multiple sclerosis | Doctor of Philosophy | Doctorate | Part Time | Miss Madison Boda |
| 2021 | Co-Supervisor | Investigating inducing plasticity in cortical circuits using repetitive paired pulse transcranial magnetic stimulation. | Doctor of Philosophy | Doctorate | Part Time | Mr Suraj Suresh |
| 2021 | Co-Supervisor | The impact of different drugs on neural oscillations | Doctor of Philosophy | Doctorate | Part Time | Miss Marissa Marina Holden |
| 2021 | Co-Supervisor | Investigating inducing plasticity in cortical circuits using repetitive paired pulse transcranial magnetic stimulation. | - | Doctorate | Part Time | Mr Suraj Suresh |
| 2021 | Co-Supervisor | The impact of different drugs on neural oscillations | - | Doctorate | Part Time | Miss Marissa Marina Holden |
| 2021 | Co-Supervisor | The impact of different drugs on neural oscillations | Doctor of Philosophy | Doctorate | Part Time | Miss Marissa Marina Holden |
| 2021 | Co-Supervisor | Investigating inducing plasticity in cortical circuits using repetitive paired pulse transcranial magnetic stimulation. | Doctor of Philosophy | Doctorate | Part Time | Mr Suraj Suresh |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2022 - 2025 | Co-Supervisor | Non-invasive brain stimulation in the treatment of post-stroke aphasia: challenges and opportunities for translation | Doctor of Philosophy | Doctorate | Full Time | Miss Ellen Evelyn Robison Williams |
| 2019 - 2022 | Co-Supervisor | Brain Rhythms and Working Memory in Healthy Ageing | Doctor of Philosophy | Doctorate | Full Time | Miss Sabrina Sghirripa |
| 2019 - 2022 | Co-Supervisor | A Study of Behavioural, Cognitive and Neural Markers Underlying Visuospatial Learning | Doctor of Philosophy | Doctorate | Full Time | Mr Toby Martin Branson |
| 2017 - 2020 | Co-Supervisor | Neurophysiological and Neuroendocrine Development in Adolescents Born to Women with Gestational Diabetes Mellitus | Doctor of Philosophy | Doctorate | Full Time | Mr Jago McDonald Van Dam |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2021 - 2024 | Member | Australasian Brain Stimulation Society, Executive Committee | Australasian Brain Stimulation Society | Australia |
| 2018 - 2019 | Member | NHMRC National Institute for Dementia Research, Accelerator Working Group | NHMRC National Institute for Dementia Research | Australia |
| 2017 - 2020 | Member | Australian Association of Gerontology, SA division | Australian Association of Gerontology | Australia |
| Date | Title | Engagement Type | Institution | Country |
|---|---|---|---|---|
| 2024 - 2024 | Invited Speaker, Pint of Science Festival | Public Community Engagement | Pint of Science Australia | Australia |
| 2022 - 2022 | Invited Speaker, SAHMRI Lifelong Health Outreach: “Can we really slow ageing?” | Public Community Engagement | South Australian Health and Medical Research Institute | Australia |
| 2020 - 2020 | Invited Speaker, SAHMRI Consumer and Carer Research Consultation Group | Public Community Engagement | South Australian Health and Medical Research Institute | Australia |
| 2019 - 2019 | Organiser and Chair, AAG SA Lifestyle and Healthy Brain Ageing Seminar | Public Community Engagement | Australian Association of Gerontology | Australia |
| Date | Role | Editorial Board Name | Institution | Country |
|---|---|---|---|---|
| 2025 - ongoing | Editor | Scientific Reports | Springer Nature | United Kingdom |
| Date | Event Name | Event Type | Institution | Country |
|---|---|---|---|---|
| 2019 - 2021 | Scientific Program Committee Member, Australian Dementia Forum | Conference | Australian Dementia Network | Australia |
| 2017 - 2017 | Organising Committee Member, Australasian Cognitive Neuroscience Society Conference | Conference | Australasian Cognitive Neuroscience Society | Australia |
| Date | Title | Type | Institution | Country |
|---|---|---|---|---|
| 2026 - 2026 | Detailed Assessor, ARC Discovery Program (DP27) | Grant Assessment | Australian Research Council | Australia |
| 2026 - 2026 | Detailed Assessor, ARC Discovery Program (DE27) | Grant Assessment | Australian Research Council | Australia |
| 2025 - 2026 | Detailed Assessor, ARC Discovery Program (FT26) | Grant Assessment | Australian Research Council | Australia |
| 2025 - 2025 | Expert Reviewer, UKRI Funding Service | Grant Assessment | UK Research and Innovation | United Kingdom |
| 2024 - 2024 | Detailed Assessor, ARC Discovery Program (DP25) | Grant Assessment | Australian Research Council | Australia |
| 2023 - 2023 | Detailed Assessor, ARC Discovery Program (DP24) | Grant Assessment | Australian Research Council | Australia |
| 2023 - 2023 | Detailed Assessor, ARC Discovery Program (DE24) | Grant Assessment | Australian Research Council | Australia |
| 2022 - 2022 | Detailed Assessor, ARC Discovery Program (DP23) | Grant Assessment | Australian Research Council | Australia |
| 2022 - 2022 | Detailed Assessor, ARC Discovery Program (DE23) | Grant Assessment | Australian Research Council | Australia |
| 2022 - 2022 | Detailed Assessor, ARC Discovery Program (FT22) | Grant Assessment | Australian Research Council | Australia |
| 2020 - 2020 | Reviewer, Sir Charles Hercus Research Fellowship | Grant Assessment | Health Research Council of New Zealand | New Zealand |
| 2020 - 2020 | Detailed Assessor, ARC Discovery Program (DP21) | Grant Assessment | Australian Research Council | Australia |
| 2020 - 2020 | External Reviewer, Dementia Australia Research Foundation Grants Program | Grant Assessment | Dementia Australia | Australia |
| 2017 - 2017 | External Assessor, 2017 NHMRC Project Grants | Grant Assessment | National Health and Medical Research Council | Australia |
| 2015 - 2015 | Expert Assessor, Neurological Foundation of New Zealand | Grant Assessment | Neurological Foundation of New Zealand | New Zealand |
| 2015 - 2015 | External Assessor, 2015 NHMRC Project Grants | Grant Assessment | National Health and Medical Research Council | Australia |