Dr Miguel De Barros Lopes

Dr Miguel De Barros Lopes

School of Agriculture, Food and Wine

College of Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

I received my Bachelor of Science degree at the University of Oregon and my PhD at the University of California. My PhD research characterised genes involved in pheromone signalling in fungi. 
I joined the University of South Australia in 2004 where I teach courses in microbiology and invertebrate and vertebrate biology.
My research has focused on the genetics of the yeast Saccharomyces and the ecology of fungi in foods/wines and natural systems.  A main area of recent interest is the interaction between animals and microbes.

Year Citation
2025 Scott, S., de Barros Lopes, M., Gibbs, J., & Petit, S. (2025). Effects of prescribed fire on body condition, injury frequency, and recapture of reptiles in Mediterranean-type eucalypt forests. Forest Ecology and Management, 586(122683), 1-16.
DOI Scopus1 WoS1
2022 Besedin, D., Turner, B. J., Deo, P., De Barros Lopes, M., & Williams, C. R. (2022). Effect of captivity and water salinity on culture-dependent frog skin microbiota and Batrachochytrium dendrobatidis (Bd) infection. Transactions of the Royal Society of South Australia, 146(2), 273-294.
DOI Scopus1 WoS1
2020 Parker, M., Onetto, C., Hixson, J., Bilogrevic, E., Schueth, L., Pisaniello, L., . . . Francis, L. (2020). Factors Contributing to Interindividual Variation in Retronasal Odor Perception from Aroma Glycosides: The Role of Odorant Sensory Detection Threshold, Oral Microbiota, and Hydrolysis in Saliva. Journal of Agricultural and Food Chemistry, 68(38), 10299-10309.
DOI Scopus38 WoS35 Europe PMC25
2020 Amsalu, A., Sapula, S. A., Lopes, M. D. B., Hart, B. J., Nguyen, A. H., Drigo, B., . . . Venter, H. (2020). Efflux pump-driven antibiotic and biocide cross-resistance in pseudomonas Aeruginosa isolated from different ecological Niches: a case study in the development of multidrug resistance in environmental hotspots. Microorganisms, 8(11), 1-18.
DOI Scopus81 WoS75 Europe PMC56
2018 Wang, Y., Mowla, R., Ji, S., Guo, L., De Barros Lopes, M. A., Jin, C., . . . Venter, H. (2018). Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors. European journal of medicinal chemistry, 143, 699-709.
DOI Scopus35 WoS35 Europe PMC27
2018 Siebert, T. E., Barker, A., Pearson, W., Barter, S. R., De Barros Lopes, M. A., Darriet, P., . . . Francis, I. L. (2018). Volatile Compounds Related to 'Stone Fruit' Aroma Attributes in Viognier and Chardonnay Wines. Journal of Agricultural and Food Chemistry, 66(11), 2838-2850.
DOI Scopus66 WoS58 Europe PMC36
2018 Siebert, T. E., Barker, A., Barter, S. R., de Barros Lopes, M. A., Herderich, M. J., & Francis, I. L. (2018). Analysis, potency and occurrence of (Z)-6-dodeceno-γ-lactone in white wine. Food Chemistry, 256, 85-90.
DOI Scopus9 WoS8 Europe PMC3
2018 Siebert, T. E., Barter, S. R., de Barros Lopes, M. A., Herderich, M. J., & Francis, I. L. (2018). Investigation of 'stone fruit’ aroma in Chardonnay, Viognier and botrytis Semillon wines. Food Chemistry, 256, 286-296.
DOI Scopus57 WoS52 Europe PMC28
2017 Wang, Y., Mowla, R., Guo, L., Ogunniyi, A. D., Rahman, T., De Barros Lopes, M. A., . . . Venter, H. (2017). Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. Bioorganic and Medicinal Chemistry Letters, 27(4), 733-739.
DOI Scopus35 WoS32 Europe PMC26
2014 Madigan, T., Bott, N., Torok, V., Percy, N., Carragher, J., Lopes, M., & Kiermeier, A. (2014). A microbial spoilage profile of half shell Pacific oysters (Crassostrea gigas) and Sydney rock oysters (Saccostrea glomerata). Food Microbiology, 38, 219-227.
DOI Scopus57 WoS51 Europe PMC36
2013 Madigan, T., Kiermeier, A., Carragher, J., de Barros Lopes, M., & Cozzolino, D. (2013). The use of rapid instrumental methods to assess freshness of half shell Pacific oysters, Crassostrea gigas: A feasibility study. Innovative Food Science and Emerging Technologies, 19, 204-209.
DOI Scopus16 WoS16 Europe PMC4
2013 Halloway, K. L., Henneberg, R., De Barros Lopes, M., Staub, K., Link, K., Rühli, F., & Henneberg, M. (2013). Secular trends in tuberculosis during the second epidemiological transition: a Swiss perspective. Advances in anthropology, 3(2), 78-90.
DOI
2012 Madigan, T., Kiermeier, A., de Barros Lopes, M., & Cozzolino, D. (2012). The effect of homogenisation and storage on the near-infrared spectra of half shell Pacific Oysters (Crassostrea gigas). Food Analytical Methods, 5(5), 995-1002.
DOI Scopus8 WoS8
2012 Callegari, S., Gregory, P., Sykes, M., Bellon, J., Andrews, S., McKinnon, R., & de Barros Lopes, M. (2012). Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity. PLoS Genetics, 8(6), 1-12.
DOI Scopus6 WoS6 Europe PMC5
2012 Jatmiko, Y. D., De Barros Lopes, M., & Barton, M. D. (2012). Molecular identification of Yeasts isolated from Dadih by RFLP-PCR and assessment on their ability in utilizing lactate. Microbiology Indonesia, 6(1), 30-34.
DOI
2011 Holloway, K., Henneberg, R., de Barros Lopes, M., & Henneberg, M. (2011). Evolution of human tuberculosis: A systematic review and meta-analysis of paleopathological evidence. Homo - journal of comparative human biology, 62(6), 402-458.
DOI Scopus65 WoS58 Europe PMC32
2011 Callegari, S., McKinnon, R. A., Andrews, S., & De Barros, L. M. (2011). The MEF2 gene is essential for yeast longevity, with a dual role in cell respiration and maintenance of mitochondrial membrane potential. FEBS letters, 585(8), 1140-1146.
DOI Scopus9 WoS7 Europe PMC10
2011 Bellon, J., Eglinton, J., Siebert, T., Pollnitz, A., Rose, L., De Barros Lopes, M., & Chambers, P. (2011). Newly generated interspecific wine yeast hybrids introduce flavour and aroma diversity to wines. Applied Microbiology and Biotechnology, 91(3), 603-612.
DOI Scopus81 WoS81 Europe PMC62
2010 Callegari, S., McKinnon, R. A., Andrews, S., & De, B. L. M. (2010). Atorvastatin-induced cell toxicity in yeast is linked to disruption of protein isoprenylation. FEMS yeast research, 10(2), 188-198.
DOI Scopus21 WoS23 Europe PMC20
2009 Schmidt, S. A., Tan, E. L., Brown, S., Nasution, U. J., Pettolino, F., Macintyre, O. J., . . . Anderson, P. A. (2009). Hpf2 Glycan structure is critical for protection against protein haze formation in white wine. Journal of Agricultural and Food Chemistry, 57(8), 3308-3315.
DOI Scopus23 WoS21 Europe PMC14
2007 Curtin, C. D., Bellon, J. R., Henschke, P. A., Godden, P. W., & De Barros Lopes, M. A. (2007). Genetic diversity of Dekkera bruxellensis yeasts isolated from Australian wineries. FEMS Yeast Research, 7(3), 471-481.
DOI Scopus83 Europe PMC49
2007 Curtin, C. D., Bellon, J. R., Henschke, P. A., Godden, P. W., & de Barros Lopes, M. A. (2007). Genetic diversity of Dekkera bruxellensis yeasts isolated from Australian wineries. FEMS Yeast Research, 7(3), 471-481.
DOI
2007 Brown, S., Stockdale, V., Pettolina, F., Pocock, K., de Barros Lopes, M., Williams, P., . . . Waters, E. (2007). Reducing haziness in white wine by overexpression of Saccharomyces cerevisiae genes YOL155c and YDR055w. Applied Microbiology and Biotechnology, 73(6), 1363-1376.
DOI Scopus62 WoS59 Europe PMC37
2006 McBryde, C., Gardner, J., de Barros Lopes, M., & Jiranek, V. (2006). Generation of novel wine yeast strains by adaptive evolution. American Journal of Enology and Viticulture, 57(4), 423-430.
DOI Scopus59 WoS53
2006 Cozzolino, D., Flood, L., Bellon, J., Gishen, M., & De Barros Lopes, M. (2006). Combining near infrared spectoscopy and multivariate analysis as a tool to differentiate different strains of saccharomyces cerevisiae: a metabolomic study. Yeast: a forum for yeast researchers, 23(14-15), 1089-1096.
DOI Scopus25 WoS20 Europe PMC8
2005 Howell, K., Klein, M., Swiegers, J., Hayasaka, Y., Elsey, G., Fleet, G., . . . de Barros Lopes, M. (2005). Genetic determinants of volatile-thiol release by Saccharomyces cerevisiae during wine fermentation. Applied and Environmental Microbiology, 71(9), 5420-5426.
DOI Scopus101 WoS87 Europe PMC58
2005 Gardner, J., McBryde, C., Vystavelova, A., de Barros Lopes, M., & Jiranek, V. (2005). Identification of genes affecting glucose catabolism in nitrogen-limited fermentation. FEMS Yeast Research, 5(9), 791-800.
DOI Scopus18 WoS19 Europe PMC11
2004 Howell, K., Swiegers, J., Elsey, G., Siebert, T., Bartowsky, E., Fleet, G., . . . de Barros Lopes, M. (2004). Variation in 4-mercapto-4-methyl-pentan-2-one release by saccharomyces cerevisiae commercial wine strains. FEMS Microbiology Letters, 240(2), 125-129.
DOI Scopus115 Europe PMC54
2003 Walker, M., Gardner, J., Vystavelova, A., McBryde, C., de Barros Lopes, M., & Jiranek, V. (2003). Application of the reuseable, KanMX selectable marker to industrial yeast: construction and evaluation of heterothallic wine strains of Saccharomyces cerevisiae, possessing minimal foreign DNA sequences. FEMS Yeast Research, 4(3), 339-347.
DOI Scopus57 WoS54 Europe PMC42
2003 O'Halloran, C., Henschke, P., Langridge, P., & de Barros Lopes, M. (2003). Subunit and cofactor binding of Saccharomyces cerevisiae sulfite reductase - towards developing wine yeast with lowered ability to produce hydrogen sulfide. Australian Journal of Grape and Wine Research, 9(3), 186-193.
DOI Scopus19 WoS15
2003 Gecz, J., Shaw, M., Bellon, J., & de Barros Lopes, M. (2003). Human wild-type SEDL protein functionally complements yeast Trs20p but some naturally occurring SEDL mutants do not. Gene, 320(1-2), 137-144.
DOI Scopus31 WoS30 Europe PMC26
2002 Eglinton, J., Heinrich, A., Pollnitz, A., Langridge, P., Henschke, P., & de Barros Lopes, M. (2002). Decreasing acetic acid accumulation by a glycerol overproducing strain of Saccharomyces cerevisiae by deleting the ALD6 aldehyde dehydrogenase gene. Yeast, 19(4), 295-301.
DOI Scopus141 WoS124 Europe PMC75
2002 De Barros Lopes, M., Bellon, J., Shirley, N., & Ganter, P. (2002). Evidence for multiple interspecific hybridisation in Saccharomyces sensu stricto species. FEMS Yeast Research, 1(4), 323-331.
DOI Scopus122 Europe PMC78
2000 De Barros Lopes, M., Ata-Ur-Rehman., Gockowiak, H., Heinrich, A., Langridge, P., & Henschke, P. (2000). Fermentation properties of a wine yeast over-expressing the Saccharomyces cerevisiae glycerol 3-phosphate dehydrogenase gene (GPD2). Australian Journal of Grape and Wine Research, 6(3), 208-215.
Scopus54
2000 Yap, N., de Barros Lopes, M., Langridge, P., & Henschke, P. (2000). The incidence of killer activity of non-Saccharomyces yeasts towards indigenous yeast species of grape must: potential application in wine fermentation. Journal of Applied Microbiology, 89(3), 381-389.
DOI Scopus54 WoS46 Europe PMC30
2000 Ganter, P. F., & De Barros Lopes, M. (2000). The use of anonymous DNA markers in assessing worldwide relatedness in the yeast species Pichia kluyveri Bedford and Kudrjavzev. Canadian Journal of Microbiology, 46(11), 967-980.
DOI Scopus16 Europe PMC9
1998 De Barros Lopes, M., Soden, A., Martens, A. L., Henschke, P. A., & Langridge, P. (1998). Differentiation and species identification of yeasts using PCR. International Journal of Systematic Bacteriology, 48(1), 279-286.
DOI Scopus85 WoS75 Europe PMC31
1996 De Barros Lopes, M., Soden, A., Henschke, P. A., & Langridge, P. (1996). PCR differentiation of commercial yeast strains using intron splice site primers. Applied and Environmental Microbiology, 62(12), 4514-4520.
DOI Scopus105 WoS87 Europe PMC61
1991 Stone, D. E., Cole, G. M., De Barros Lopes, M., Goebl, M., & Reed, S. I. (1991). N-myristoylation is required for function of the pheromone-responsive Gα protein of yeast: Conditional activation of the pherpmone response by a temperature-sensitive N-myristoyl transferase. Genes and Development, 5(11), 1969-1981.
DOI Scopus78 Europe PMC65
1990 De Barros Lopes, M., Ho, J. Y., & Reed, S. I. (1990). Mutations in Cell Division Cycle Genes CDC36 and CDC39 Activate the Saccharomyces cerevisiae Mating Pheromone Response Pathway. Molecular and Cellular Biology, 10(6), 2966-2972.
DOI Scopus31 Europe PMC23
1989 Hadwiger, J. A., Wittenberg, C., Richardson, H. E., De Barros Lopes, M., & Reed, S. I. (1989). A family of cyclin homologs that control the G1 phase in yeast). Proceedings of the National Academy of Sciences of the United States of America, 86(16), 6255-6259.
DOI Scopus350 Europe PMC272
1985 Reed, S. I., de Barros Lopes, M. A., Ferguson, J., Hadwiger, J. A., Ho, J. Y., Horwitz, R., . . . Peterson, T. A. (1985). Genetic and molecular analysis of division control in yeast.. Cold Spring Harbor Symposia on Quantitative Biology, 50(0), 627-634.
DOI Scopus22 Europe PMC11

Year Citation
2006 de Barros Lopes, M., Bartowsky, E., & Pretorius, I. (2006). The application of gene technology in the wine industry. In Y. Hui (Ed.), Handbook of food science, technology and engineering (pp. 40-1-40-21). Boca Raton, Florida: Taylor & Francis.
2006 Pretorius, I., Bartowsky, E., de Barros Lopes, M., Bauer, F., du Toit, M., van Rensburg, P., & Vivier, M. (2006). The Tailoring of Designer Grapevines and Microbial Starter Strains for a Market-Directed and Quality-Focused Wine Industry. In Y. Hui (Ed.), Handbook of food science technology and engineering (Vol. 4, pp. 174-1-174-24). London: Taylor & Francis.
2006 Swiegers, J., Willmott, R., Hill-Ling, A., Capone, D., Pardon, K., Elsey, G., . . . Pretorius, I. (2006). Modulation of volatile thiol and ester aromas in wine by modified wine yeast. In W. Bredie, & M. Peterson (Eds.), Developments in Food Science. Flavour Science: Recent Advances and Trends (Vol. 43, pp. 113-116). The Netherlands: Elsevier.
DOI Scopus57
2006 De Barros Lopes, M., & Ganter, P. (2006). Genorne studies of cactus yeast. In Source details - Title: Plant Genome Biodiversity and Evolution (Vol. 2, pp. 459-479). New Hampshire, USA: Science Publishers Inc.
2005 De Barros Lopes, M. A., Bartowsky, E. J., & Pretorius, I. S. (2005). The application of gene technology in the wine industry. In Handbook of Food Science Technology and Engineering 4 Volume Set (pp. 731-751).
Scopus3
2005 Pretorius, I. S., Bartowsky, E. J., De Barros Lopes, M., Bauer, F. F., Du Toit, M., Van Rensburg, P., & Vivier, M. A. (2005). The tailoring of designer grapevines and microbial starter strains for a market-directed and quality-focused wine industry. In Handbook of Food Science Technology and Engineering 4 Volume Set (pp. 3065-3088).
Scopus2

  • Holsworth - Post-fire recovery and chytrid prevalence in South Australian frogs - Shawn Scott, ESA-Holsworth Wildlife Research Endowment, 18/03/2024 - 18/03/2025

Date Role Research Topic Program Degree Type Student Load Student Name
2024 Co-Supervisor What factors are causing the decline of the threatened Bibron's toadlet (Pseudophryne bibronii) in the Mount Lofty Ranges? - Master Part Time Mr Thomas Prosser
2021 Co-Supervisor Fire ecology and succession of Herpetofauna, with implications for conservation management, in the Mount Lofty Ranges Doctor of Philosophy Doctorate Full Time Mr Shawn William Scott
2019 Co-Supervisor Risk factors in the development and dissemination of antimicrobial resistance in residential age care facilities Doctor of Philosophy Doctorate Part Time Mrs Naomi Siderius
2019 Principal Supervisor Understanding the chemical basis of 'jammy' character in red wine and grapes Doctor of Philosophy Doctorate Part Time Miss Jana Hildebrandt

Date Role Research Topic Program Degree Type Student Load Student Name
2010 - 2013 External Supervisor Tuberculosis is an Evolving Disease: Paleoepidemiological and Historical Evidence Doctor of Philosophy Doctorate Full Time Miss Kara Lee Holloway
2002 - 2006 Co-Supervisor Development of Novel Wine Yeast Strains Using Adaptive Evolution Doctor of Philosophy Doctorate Full Time Mr Colin McBryde
2000 - 2006 Co-Supervisor Identification of Genomic Differences Between Laboratory and Commercial Strains of Saccharomyces Cerevisiae Doctor of Philosophy Doctorate Full Time Mr Anthony Heinrich
1999 - 2004 Co-Supervisor Investigation into the mechanism of action and biological role of Saccharomyces cerevisiae mannoproteins which reduce visible haziness in white wine Doctor of Philosophy Doctorate Full Time Dr Shauna Liam Hockley
1999 - 2006 Co-Supervisor Identification of Genes affecting Glucose Catabolism in Nitrogen-limited Fermentation Doctor of Philosophy Doctorate Full Time Dr Jennifer Gardner
1998 - 2002 Co-Supervisor Enhancing yeast performance under oenological conditions by enabling proline utilisation Doctor of Philosophy Doctorate Full Time Ms Kathryn Poole

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