2024 |
Lardelli, M., Baer, L., Hin, N., Allen, A., Pederson, S. M., & Barthelson, K. (2024). The Use of Zebrafish in Transcriptome Analysis of the Early Effects of Mutations Causing Early Onset Familial Alzheimer's Disease and Other Inherited Neurodegenerative Conditions. Journal of Alzheimer's Disease, 99(s2), S367-S381. DOI Scopus2 Europe PMC1 |
2024 |
Baer, L., Barthelson, K., Postlethwait, J. H., Adelson, D. L., Pederson, S. M., & Lardelli, M. (2024). Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis. PLoS Computational Biology, 20(2 February), 27 pages. DOI |
2024 |
Hillman, C., Fontana, B. D., Amstislavskaya, T. G., Gorbunova, M. A., Altenhofen, S., Barthelson, K., . . . Parker, M. O. (2024). Housing and Husbandry Factors Affecting Zebrafish (Danio rerio) Novel Tank Test Responses: A Global Multi-Laboratory Study.. Res Sq. DOI |
2023 |
Barthelson, K., Hemsley, K., & Lardelli, M. (2023). Transcriptome analysis of early-onset familial Alzheimer’s disease and Sanfilippo syndrome zebrafish models reveals commonalities in disease mechanisms. DOI |
2023 |
Baer, L., Barthelson, K., Postlethwait, J., Adelson, D., Pederson, S., & Lardelli, M. (2023). Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis. bioRxiv. DOI |
2023 |
Lardelli, M. (2023). An Alternative View of Familial Alzheimer’s Disease Genetics. DOI |
2023 |
Lardelli, M. (2023). An Alternative View of Familial Alzheimer’s Disease Genetics. DOI |
2023 |
Ha, T. T., Burgess, R., Newman, M., Moey, C., Mandelstam, S. A., Gardner, A. E., . . . Corbett, M. A. (2023). Aicardi Syndrome Is a Genetically Heterogeneous Disorder. Genes, 14(8), 1565. DOI |
2023 |
Allen, A. G., Barthelson, K., & Lardelli, M. (2023). PHAPE: A plasmid for production of DNA size marker ladders for gel electrophoresis. Biology Methods and Protocols, 8(1), 8 pages. DOI |
2023 |
Gerken, E., Ahmad, S., Rattan, L., Hemsley, K., Hemsley, K., Suo, S., . . . Lardelli, M. (2023). Zebrafish models of Mucopolysaccharidosis types IIIA, B, & C show hyperactivity and changes in oligodendrocyte state. DOI |
2023 |
Lardelli, M. (2023). An Alternative View of Familial Alzheimer's Disease Genetics.. Journal of Alzheimer's disease : JAD, 96(1), 1-27. DOI Scopus7 WoS1 Europe PMC6 |
2022 |
Barthelson, K., Newman, M., & Lardelli, M. (2022). Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism. Disease Models and Mechanisms, 15(1), 1-14. DOI Scopus5 WoS1 Europe PMC2 |
2022 |
Allen, A., Barthelson, K., & Lardelli, M. (2022). pHAPE: a plasmid for production of DNA size marker ladders for gel electrophoresis. DOI |
2021 |
Coulson, M., Searle, I., Richards, R., Tucker, M. R., Bakaj, N., Bertozzi, T., . . . Lardelli, M. (2021). Multiple learning and administrative advantages when an advanced course in genetics adopted a “flipped-classroom” format with continuous, online assessment. DOI |
2021 |
Jayne, T., Newman, M., Baer, L., & Lardelli, M. (2021). The evolved divergence of γ-secretase-susceptibility of homologous proteins Ngfrb and Nradd in zebrafish. BMC Research Notes, 14(1), 1-5. DOI |
2021 |
Chin, H. Y., Lardelli, M., Collins-Praino, L., & Barthelson, K. (2021). Differential effects of loss of<i>park7</i>activity on Iron Responsive Element (IRE) gene sets: Implications for the role of iron dyshomeostasis in the pathophysiology of Parkinson’s disease. DOI |
2021 |
Barthelson, K., Pederson, S. M., Newman, M., Jiang, H., & Lardelli, M. (2021). In-Frame and Frameshift Mutations in Zebrafish Presenilin 2 Affect Different Cellular Functions in Young Adult Brains. Journal of Alzheimer's Disease Reports, 5(1), 395-404. DOI Scopus7 WoS5 Europe PMC6 |
2021 |
Barthelson, K., Dong, Y., Newman, M., & Lardelli, M. (2021). PRESENILIN 1 mutations causing early-onset familial alzheimer's disease or familial acne inversa differ in their effects on genes facilitating energy metabolism and signal transduction. Journal of Alzheimers Disease, 82(1), 327-347. DOI Scopus6 WoS2 Europe PMC5 |
2021 |
Chin, H. Y., Lardelli, M., Collins-Praino, L., & Barthelson, K. (2021). Loss of park7 activity has differential effects on expression of iron responsive element (IRE) gene sets in the brain transcriptome in a zebrafish model of Parkinson's disease.. Mol Brain, 14(1), 83. DOI Scopus8 WoS6 Europe PMC5 |
2021 |
Barthelson, K., Baer, L., Dong, Y., Hand, M., Pujic, Z., Newman, M., . . . Lardelli, M. (2021). Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome. Frontiers in Genetics, 12, 1-11. DOI Scopus3 Europe PMC4 |
2021 |
Hin, N., Newman, M., Pederson, S., & Lardelli, M. (2021). Iron responsive element-mediated responses to iron dyshomeostasis in Alzheimer's disease. Journal of Alzheimers Disease, 84(4), 1-34. DOI Scopus14 WoS6 Europe PMC17 |
2021 |
Hin, N., Newman, M., Pederson, S., & Lardelli, M. (2021). Iron Responsive Element (IRE)-mediated responses to iron dyshomeostasis in Alzheimer's disease. Journal of Alzheimer's Disease, 84(4), 1597-1630. DOI |
2021 |
Barthelson, K., Pederson, S. M., Newman, M., & Lardelli, M. (2021). Brain transcriptome analysis of a protein-truncating mutation in sortilin-related receptor 1 associated with early-onset familial alzheimer's disease indicates early effects on mitochondrial and ribosome function. Journal of Alzheimer's Disease, 79(3), 1105-1119. DOI Scopus7 WoS4 Europe PMC6 |
2021 |
Barthelson, K., Newman, M., Nowell, C. J., & Lardelli, M. (2021). No observed effect on brain vasculature of Alzheimer's disease-related mutations in the zebrafish presenilin 1 gene. Molecular Brain, 14(1), 22-1-22-4. DOI Scopus1 WoS1 Europe PMC1 |
2021 |
Barthelson, K., Dong, Y., Newman, M., & Lardelli, M. (2021). <i>PRESENILIN 1</i>mutations causing early-onset familial Alzheimer’s disease or familial acne inversa differ in their effects on genes facilitating energy metabolism and signal transduction. DOI |
2021 |
Barthelson, K., Newman, M., & Lardelli, M. (2021). Comparative analysis of Alzheimer’s disease knock-in model brain transcriptomes implies changes to energy metabolism as a causative pathogenic stress. DOI |
2021 |
Dong, Y., Newman, M., Pederson, S. M., Barthelson, K., Hin, N., & Lardelli, M. (2021). Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer’s disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM functions, and iron homeostasis. BMC Genomics, 22(1), 211-1-211-16. DOI Scopus9 WoS6 Europe PMC5 |
2021 |
Moussavi Nik, S. H., Porter, T., Newman, M., Bartlett, B., Khan, I., Sabale, M., . . . Verdile, G. (2021). Relevance of a truncated PRESENILIN 2 transcript to Alzheimer's disease and neurodegeneration.. Journal of Alzheimer's Disease, 80(4), 1-11. DOI Scopus3 WoS2 Europe PMC3 |
2020 |
Barthelson, K., Pederson, S. M., Newman, M., & Lardelli, M. (2020). Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease. biorxiv. DOI |
2020 |
Jiang, H., Pederson, S. M., Newman, M., Dong, Y., & Lardelli, M. (2020). Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene<i>psen2</i>. DOI |
2020 |
Newman, M., Moussavi Nik, S. H., Sutherland, G. T., Hin, N., Kim, W. S., Halliday, G. M., . . . Lardelli, M. (2020). Accelerated loss of hypoxia response in zebrafish with familial Alzheimer's disease-like mutation of Presenilin 1. Human Molecular Genetics, 29(14), 2379-2394. DOI Scopus10 WoS8 Europe PMC7 |
2020 |
Barthelson, K., Newman, M., & Lardelli, M. (2020). Sorting Out the Role of the Sortilin-Related Receptor 1 in Alzheimer's Disease. Journal of Alzheimer’s Disease Reports, 4(1), 123-140. DOI Scopus20 WoS13 Europe PMC13 |
2020 |
Jiang, H., Pederson, S. M., Newman, M., Dong, Y., Barthelson, K., & Lardelli, M. (2020). Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2. PLoS One, 15(7), e0232559-1-e0232559-25. DOI Scopus6 WoS3 Europe PMC4 |
2020 |
Barthelson, K., Pederson, S. M., Newman, M., & Lardelli, M. (2020). Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer's disease.. Molecular brain, 13(1), 142. DOI Scopus22 WoS14 Europe PMC16 |
2020 |
Barthelson, K., Pederson, S., Newman, M., & Lardelli, M. (2020). Transcriptome analysis of a protein-truncating mutation in sortilin-related receptor 1 associated with early-onset familial Alzheimer’s disease indicates effects on mitochondrial and ribosome function in young-adult zebrafish brains. biorxiv. DOI |
2020 |
Barthelson, K., Pederson, S. M., Newman, M., Jiang, H., & Lardelli, M. (2020). Frameshift and frame-preserving mutations in zebrafish presenilin 2 affect different cellular functions in young adult brains. DOI |
2020 |
Hin, N., Newman, M., Kaslin, J., Douek, A. M., Lumsden, A., Moussavi Nik, S. H., . . . Lardelli, M. (2020). Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. PloS one, 15(1), e0227258. DOI Scopus22 WoS17 Europe PMC16 |
2019 |
Newman, M., Hin, N., Pederson, S., & Lardelli, M. (2019). A familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene affects brain energy production. DOI |
2019 |
Newman, M., Nik, H. M., Sutherland, G., Hin, N., Kim, W., Halliday, G., . . . Lardelli, M. (2019). Accelerated loss of hypoxia response in zebrafish with familial Alzheimer’s disease-like mutation of Presenilin 1. DOI |
2019 |
Newman, M., Hin, N., Pederson, S., & Lardelli, M. (2019). Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Molecular Brain, 12(1), 1-5. DOI Scopus20 WoS18 Europe PMC15 |
2019 |
Braggin, J. E., Bucks, S. A., Course, M. M., Smith, C. L., Sopher, B., Osnis, L., . . . Jayadev, S. (2019). Alternative splicing in a presenilin 2 variant associated with Alzheimer disease. Annals of Clinical and Translational Neurology, 6(4), 762-777. DOI Scopus27 WoS21 Europe PMC16 |
2018 |
Lumsden, A., Rogers, J., Majd, S., Newman, M., Sutherland, G., Verdile, G., & Lardelli, M. (2018). Dysregulation of neuronal iron homeostasis as an alternative unifying effect of mutations causing familial Alzheimer's disease. Frontiers in Neuroscience, 12(AUG), 533-1-533-21. DOI Scopus36 WoS29 Europe PMC24 |
2018 |
Nik, S. H. M., Newman, M., Lumsden, A., Jayne, T., & Lardelli, M. (2018). HMGA1 zebrafish co-orthologue hmga1b can modulate p53-dependent cellular responses but is unable to control the alternative splicing of psen1. DOI |
2018 |
Jiang, H., Newman, M., & Lardelli, M. (2018). The zebrafish orthologue of familial Alzheimer's disease gene PRESENILIN 2 is required for normal adult melanotic skin pigmentation. PLoS ONE, 13(10), e0206155-1-e0206155-20. DOI Scopus20 WoS16 Europe PMC10 |
2018 |
Jiang, H., Jayadev, S., Lardelli, M., & Newman, M. (2018). A Review of the Familial Alzheimer's Disease Locus PRESENILIN 2 and Its Relationship to PRESENILIN 1. Journal of Alzheimer's Disease, 66(4), 1323-1339. DOI Scopus15 WoS11 Europe PMC10 |
2018 |
Ratnayake, D., Newman, M., & Lardelli, M. (2018). Degenerate codon mixing for PCR-based manipulation of highly repetitive sequences. BMC Research Notes, 11(1), 202-1-202-7. DOI Scopus1 Europe PMC1 |
2018 |
Hin, N., Newman, M., Kaslin, J., Douek, A. M., Lumsden, A., Zhou, X., . . . Lardelli, M. (2018). Accelerated brain aging towards transcriptional inversion in a zebrafish model of familial Alzheimer's disease. BioRxiv, OnlinePubl. DOI |
2017 |
Newman, M., Halter, L., Lim, A., & Lardelli, M. (2017). Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer’s disease. PLoS ONE, 12(6), e0179859-1-e0179859-17. DOI Scopus3 WoS2 Europe PMC2 |
2016 |
Ebrahimie, E., Moussavi Nik, S., Newman, M., Van Der Hoek, M., & Lardelli, M. (2016). The Zebrafish equivalent of Alzheimer's disease-associated PRESENILIN Isoform PS2V regulates inflammatory and other responses to hypoxic stress. Journal of Alzheimer's Disease, 52(2), 581-608. DOI Scopus14 WoS12 Europe PMC12 |
2016 |
Jayne, T., Newman, M., Verdile, G., Sutherland, G., Münch, G., Musgrave, I., . . . Lardelli, M. (2016). Evidence for and against a pathogenic role of reduced γ-secretase activity in familial Alzheimer's disease. Journal of Alzheimer's Disease, 52(3), 781-799. DOI Scopus36 WoS27 Europe PMC27 |
2016 |
Richards, R., Robertson, S., O'Keefe, L., Fornarino, D., Scott, A., Lardelli, M., & Baune, B. (2016). The enemy within: innate surveillance-mediated cell death, the common mechanism of neurodegenerative disease. Frontiers in Neuroscience, 10(MAY), 193-1-193-20. DOI Scopus33 WoS27 Europe PMC21 |
2015 |
Moussavi Nik, S., Newman, M., Wilson, L., Ebrahimie, E., Wells, S., Musgrave, I., . . . Lardelli, M. (2015). Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity. Human Molecular Genetics, 24(13), 3662-3678. DOI Scopus26 WoS22 Europe PMC14 |
2015 |
Lim, A., Moussavi Nik, S., Ebrahimie, E., & Lardelli, M. (2015). Analysis of nicastrin gene phylogeny and expression in zebrafish. Development Genes and Evolution, 225(3), 171-178. DOI Scopus5 WoS4 Europe PMC3 |
2014 |
Newman, M., Ebrahimie, E., & Lardelli, M. (2014). Using the zebrafish model for Alzheimer's disease research. Frontiers in Genetics, 5(JUN), 189-1-189-10. DOI Scopus114 WoS92 Europe PMC55 |
2014 |
Ganesan, S., Moussavi Nik, S., Newman, M., & Lardelli, M. (2014). Identification and expression analysis of the zebrafish orthologues of the mammalian MAP1LC3 gene family. Experimental Cell Research, 328(1), 228-237. DOI Scopus10 WoS11 Europe PMC5 |
2014 |
Nik, S., Croft, K., Mori, T., & Lardelli, M. (2014). The comparison of methods for measuring oxidative stress in zebrafish brains. Zebrafish, 11(3), 248-254. DOI Scopus12 WoS10 Europe PMC7 |
2014 |
Newman, M., Wilson, L., Verdile, G., Lim, A., Khan, I., Nik, S., . . . Lardelli, M. (2014). Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease. Human Molecular Genetics, 23(3), 602-617. DOI Scopus46 WoS40 Europe PMC27 |
2014 |
Moussavi Nik, S. H., Newman, M., Ganesan, S., Chen, M., Martins, R., Verdile, G., & Lardelli, M. (2014). Hypoxia alters expression of Zebrafish Microtubule-associated protein Tau (mapta, maptb) gene transcripts. BMC Research Notes, 7(1), 767-1-767-9. DOI Scopus20 Europe PMC6 |
2014 |
Klarić, T., Lardelli, M., Key, B., Koblar, S., & Lewis, M. (2014). Activity-dependent expression of neuronal PAS domain-containing protein 4 (npas4a) in the developing zebrafish brain. Frontiers in Neuroanatomy, 8(DEC), 148-1-148-13. DOI Scopus19 WoS16 Europe PMC13 |
2013 |
Wilson, L., & Lardelli, M. (2013). The development of an in vivo γ-secretase assay using zebrafish embryos. Journal of Alzheimer's Disease, 36(3), 521-534. DOI Scopus9 WoS8 Europe PMC4 |
2013 |
Sharman, M., Moussavi Nik, S., Chen, M., Ong, D., Wijaya, L., Laws, S., . . . Verdile, G. (2013). The Guinea Pig as a model for sporadic Alzheimer's Disease (AD): the impact of cholesterol intake on expression of AD-related genes. PLoS One, 8(6), 1-12. DOI Scopus35 WoS31 Europe PMC24 |
2012 |
Avdesh, A., Chen, M., Martin-Iverson, M., Mondal, A., Ong, D., Rainey-Smith, S., . . . Martins, R. (2012). Regular care and maintenance of a Zebrafish (Danio rerio) laboratory: an introduction. Journal of Visualized Experiments, (69), 1-8. DOI Scopus314 WoS230 Europe PMC115 |
2012 |
Newman, M., Nornes, S., Martins, R., & Lardelli, M. (2012). Robust homeostasis of Presenilin1 protein levels by transcript regulation. Neuroscience Letters, 519(1), 14-19. DOI Scopus6 WoS5 Europe PMC4 |
2012 |
Moussavi Nik, S., Wilson, L., Newman, M., Croft, K., Mori, T., Musgrave, I., & Lardelli, M. (2012). The BACE1-PSEN-AβPP regulatory axis has an ancient role in response to low oxygen/oxidative stress. Journal of Alzheimer's Disease, 28(3), 515-530. DOI Scopus48 WoS23 Europe PMC29 |
2012 |
Avdesh, A., Martin-Iverson, M., Mondal, A., Chen, M., Askraba, S., Newman, M., . . . Martins, R. (2012). Evaluation of color preference in zebrafish for learning and memory. Journal of Alzheimer's Disease, 28(2), 459-469. DOI Scopus106 WoS92 Europe PMC43 |
2012 |
Chen, M., Tegg, M., Avdesh, A., Mondal, A., Lardelli, M., Verdile, G., & Martins, R. (2012). P4‐121: Analysis of insulin‐degrading enzyme (IDE) expression and function in zebrafish embryos. Alzheimer's & Dementia, 8(4S_Part_18). DOI |
2011 |
Sugano, Y., & Lardelli, M. (2011). Identification and expression analysis of the zebrafish orthologue of Klotho. Development Genes and Evolution, 221(3), 179-186. DOI Scopus15 WoS12 Europe PMC10 |
2011 |
Wells, S., Nornes, S., & Lardelli, M. (2011). Transgenic zebrafish recapitulating tbx16 gene early developmental expression. PLoS One, 6(6), e21559-1-e21559-6. DOI Scopus11 WoS10 Europe PMC8 |
2011 |
Moussavi Nik, S., Newman, M., & Lardelli, M. (2011). The response of HMGA1 to changes in oxygen availability is evolutionarily conserved. Experimental Cell Research, 317(11), 1503-1512. DOI Scopus21 WoS20 Europe PMC17 |
2011 |
Newman, M., Verdile, G., Martins, R., & Lardelli, M. (2011). Zebrafish as a tool in Alzheimer's disease research. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1812(3), 346-352. DOI Scopus61 WoS45 Europe PMC28 |
2010 |
Newman, M., & Lardelli, M. (2010). A hyperactive sleeping beauty transposase enhances transgenesis in zebrafish embryos. BMC Research Notes, 3(1), 282-286. DOI Scopus7 Europe PMC5 |
2010 |
Wells, S., Conran, J., Tamme, R., Gaudin, A., Webb, J., & Lardelli, M. (2010). Cryptic organisation within an apparently irregular rostrocaudal distribution of interneurons in the embryonic zebrafish spinal cord. Experimental Cell Research, 316(19), 3292-3303. DOI Scopus1 WoS1 Europe PMC3 |
2010 |
Newman, M., Wilson, L., Camp-Dotlic, E., Verdile, G., Martins, R., & Lardelli, M. (2010). A zebrafish melanophore model of amyloidβ toxicity. Zebrafish, 7(2), 155-159. DOI Scopus19 WoS19 Europe PMC12 |
2010 |
Aleklett, K., Hook, M., Jakobsson, K., Lardelli, M., Snowden, S., & Soderbergh, B. (2010). The peak of the oil age - Analyzing the world oil production reference scenario in world energy outlook 2008. Energy Policy, 38(3), 1398-1414. DOI Scopus270 WoS203 |
2009 |
Chen, M., Martins, R., & Lardelli, M. (2009). Complex splicing and neural expression of duplicated Tau genes in zebrafish embryos. Journal of Alzheimer's Disease, 18(2), 305-317. DOI Scopus49 WoS41 Europe PMC28 |
2009 |
Henshall, T., Tucker, B., Lumsden, A., Nornes, S., Lardelli, M., & Richards, R. (2009). Selective neuronal requirement for Huntingtin in the developing zebrafish. Human Molecular Genetics, 18(24), 4830-4842. DOI Scopus40 WoS37 Europe PMC31 |
2009 |
Nornes, S., Newman, M., Wells, S., Verdile, G., Martins, R., & Lardelli, M. (2009). Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos. Experimental Cell Research, 316(16), 2791-2801. DOI Scopus45 WoS40 Europe PMC22 |
2009 |
Newman, M., Tucker, B., Nornes, S., Ward, A., & Lardelli, M. (2009). Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's Disease pathogenesis. Journal of Alzheimer's Disease, 16(1), 133-147. DOI Scopus26 WoS25 Europe PMC16 |
2009 |
Nornes, S., Tucker, B., & Lardelli, M. (2009). Zebrafish aplnra functions in epiboly. BMC Research Notes, 2(1), 1-6. DOI Scopus7 Europe PMC6 |
2009 |
Lardelli, M. (2009). Mining the data on coal. Science, 324(5929), 880-881. DOI Scopus6 WoS5 |
2009 |
Newman, M., Tucker, B., Nornes, S., Ward, A., & Lardelli, M. (2009). Erratum: Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis (Journal of Alzheimer's Disease (2009) 16:1 (133-147)). Journal of Alzheimer's Disease, 18(4), 993. DOI |
2008 |
Nornes, S., Newman, M., Verdile, G., Wells, S., Stoick-Cooper, C., Tucker, B., . . . Lardelli, M. (2008). Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity. Human Molecular Genetics, 17(3), 402-412. DOI Scopus44 WoS40 Europe PMC26 |
2007 |
Khut, P., Tucker, B., Lardelli, M., & Wood, S. (2007). Evolutionary and expression analysis of the zebrafish deubiquitylating enzyme, Usp9. Zebrafish, 4(2), 95-101. DOI Scopus12 WoS10 Europe PMC9 |
2007 |
Tucker, B., & Lardelli, M. (2007). A rapid apoptosis assay measuring relative acridine orange fluorescence in zebrafish embryos. Zebrafish, 4(2), 113-116. DOI Scopus118 WoS99 Europe PMC64 |
2007 |
Belle, L., Wadham, C., Crocker, L., Lardelli, M., & Khew-Goodall, Y. (2007). The protein tyrosine phosphatase Pez regulates TGFβ, epithelial–mesenchymal transition, and organ development. Journal of Cell Biology, 178(7), 1223-1235. DOI Scopus73 WoS68 Europe PMC52 |
2007 |
Lumsden, A., Henshall, T., Dayan, S., Lardelli, M., & Richards, R. (2007). Huntingtin-deficient zebrafish exhibit defects in iron utilization and development. Human Molecular Genetics, 16(16), 1905-1920. DOI Scopus133 WoS123 Europe PMC92 |
2007 |
Newman, M., Musgrave, I., & Lardelli, M. (2007). Alzheimer disease: amyloidogenesis, the presenilins and animal models. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1772(3), 285-297. DOI Scopus117 WoS103 Europe PMC66 |
2007 |
Lardelli, M. (2007). Scientists need to confront economists about peak oil. Nature, 446(7133), 257. DOI Scopus3 WoS3 Europe PMC1 |
2007 |
Tucker, B., Hepperle, C., Kortschak, R., Rainbird, B., Wells, S., Oates, A., & Lardelli, M. (2007). Zebrafish Angiotensin II receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia. Gene Expression Patterns, 7(3), 258-265. DOI Scopus27 WoS27 Europe PMC23 |
2007 |
Newman, M., Musgrave, I. F., & Lardelli, M. (2007). Corrigendum to "Alzheimer disease: Amyloidogenesis, the presenilins and animal models" [Biochim. Biophys. Acta 1772 (2007) 285-297] (DOI:10.1016/j.bbadis.2006.12.001). Biochimica et Biophysica Acta - Molecular Basis of Disease, 1772(9), 1118. DOI |
2006 |
Tucker, B., Richards, R., & Lardelli, M. (2006). Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome. Human Molecular Genetics, 15(23), 3446-3458. DOI Scopus107 WoS104 Europe PMC84 |
2004 |
Tucker, B., Richards, R., & Lardelli, M. (2004). Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships. Development Genes and Evolution, 214(11), 567-574. DOI Scopus33 WoS28 Europe PMC22 |
2004 |
Scholpp, S., Groth, C., Lohs, C., Lardelli, M., & Brand, M. (2004). Zebrafish fgfr1 is a member of the fgf8 synexpression group and is required for fgf8 signalling at the midbrain-hindbrain boundary. Development Genes and Evolution, 214(6), 285-295. DOI Scopus61 WoS53 Europe PMC47 |
2003 |
Lardelli, M. (2003). The evolutionary relationships of zebrafish genes tbx6, tbx16/spadetail and mga. Development Genes and Evolution, 213(10), 519-522. DOI Scopus17 WoS17 Europe PMC15 |
2003 |
Camp-Dotlic, E., Badhwar, P., Mann, G., & Lardelli, M. (2003). Expression analysis of a Tyrosinase promoter sequence in zebrafish. Pigment Cell Research, 16(2), 117-126. DOI Scopus14 WoS15 Europe PMC7 |
2003 |
Camp-Dotlic, E., Hope, R., Kortschak, R., Cox, T., & Lardelli, M. (2003). Expression of three spalt (sal) gene homologues in zebrafish embryos. Development Genes and Evolution, 213(1), 35-43. DOI Scopus23 WoS20 Europe PMC20 |
2003 |
Nornes, S., Groth, C., Camp-Dotlic, E., Ey, P., & Lardelli, M. (2003). Developmental control of Presenilin1 expression, endoproteolysis, and interaction in zebrafish embryos. Experimental Cell Research, 289(1), 124-132. DOI Scopus49 WoS42 Europe PMC29 |
2003 |
Lardelli, M. (2003). Something fishy in 21st century genomics. Todays Life Science, 15, 20-23. |
2002 |
Tamme, R., Wells, S., Conran, J., & Lardelli, M. (2002). The identity and distribution of neural cells expressing the mesodermal determinant spadetail. BMC Developmental Biology, 2(9), www 1-www 13. DOI |
2002 |
Groth, C., Nornes, S., Mc Carty, R., Tamme, R., & Lardelli, M. (2002). Identification of a second presenilin gene in zebrafish with similarity to the human Alzheimer's disease gene presenilin2. Development Genes and Evolution, 212(10), 486-490. DOI Scopus59 WoS52 Europe PMC35 |
2002 |
Groth, C., & Lardelli, M. (2002). The structure and function of vertebrate fibroblast growth factor receptor 1. International Journal of Developmental Biology, 46(4 Special Issue SI), 393-400. Scopus74 WoS70 Europe PMC51 |
2002 |
Tamme, R., Wells, S., Conran, J. G., & Lardelli, M. (2002). The identity and distribution of neural cells expressing the mesodermal determinant spadetail.. BMC developmental biology [electronic resource], 2(1), 9. DOI Scopus8 Europe PMC12 |
2002 |
Tamme, R., Wells, S., Conran, J., & Lardelli, M. (2002). The identity and distribution of neural cells expressing the mesodermaldeterminant spadetail. BMC Developmental Biology, 2, 1-13. DOI Scopus15 |
2002 |
Kortschak, R. D., Tamme, R., & Lardelli, M. (2002). Erratum: Evolutionary analysis of vertebrate Notch genes (Development Genes and Evolution (2001) vol. 211 (350-354)). Development Genes and Evolution, 212(3), 158. DOI |
2001 |
Holland, L. Z., Rached, L. A., Tamme, R., Holland, N. D., Kortschak, D., Inoko, H., . . . Lardelli, M. (2001). Erratum: Characterization and developmental expression of the amphioxus homolog of Notch (AmnphiNotch): Evolutionary conservation of multiple expression domains in amphioxus and vertebrates (Developmental Biology (2001) 232:2 (495-507)). Developmental Biology, 233(1), 238. DOI Scopus1 |
2001 |
Jonsson, J., Xiang, Z., Pettersson, M., Lardelli, M., & Nilsson, G. (2001). Distinct and regulated expression of Notch receptors in hematopoietic lineages and during myeloid differentiation. European Journal of Immunology, 31(11), 3240-3247. DOI Scopus46 WoS44 Europe PMC34 |
2001 |
Holland, L., Rached, L., Tamme, R., Holland, N., Inoko, H., Kortschak, R., . . . Lardelli, M. (2001). Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): Evolutionary conservation of multiple expression domains in amphioxus and vertebrates. Developmental Biology, 232(2), 493-507. DOI Scopus50 WoS48 Europe PMC33 |
2001 |
Camp-Dotlic, E., & Lardelli, M. (2001). Tyrosinase gene expression in zebrafish embryos. Development Genes and Evolution, 211(3), 150-153. DOI Scopus70 WoS60 Europe PMC44 |
2001 |
Kortschak, R., Tamme, R., & Lardelli, M. (2001). Evolutionary analysis of vertebrate Notch genes. Development Genes and Evolution, 211(7), 350-354. DOI Scopus31 WoS30 Europe PMC24 |
2001 |
Tamme, R., Mills, K., Rainbird, B., Nornes, S., & Lardelli, M. (2001). Simple, directional cDNA cloning for in situ transcript hybridization screens. Biotechniques, 31(4), 938-946. DOI Scopus6 WoS5 Europe PMC5 |
2000 |
Tamme, R., Camp-Dotlic, E., Kortschak, R., & Lardelli, M. (2000). Non-specific, nested suppression PCR method for isolation of unknown flanking DNA. Biotechniques, 28(5), 895-902. DOI Scopus10 WoS8 Europe PMC6 |
1997 |
Westin, J., & Lardelli, M. (1997). Three novel Notch genes in zebrafish: Implications for vertebrate Notch gene evolution and function. Development Genes and Evolution, 207(1), 51-63. DOI Scopus121 WoS116 Europe PMC69 |
1997 |
Zhang, H. Y., Lardelli, M., & Ekblom, P. (1997). Sequence of zebrafish fibulin-1 and its expression in developing heart and other embryonic organs. Development Genes and Evolution, 207(5), 340-351. DOI Scopus16 WoS14 Europe PMC8 |
1997 |
Lardelli, M. (1997). Generation and PCR screening of bacteriophage gamma sublibraries enriched for rare clones (the "sublibrary method").. Methods in molecular biology (Clifton, N.J.), 67, 345-355. DOI Scopus3 Europe PMC1 |
1996 |
Lardelli, M., Williams, R., Mitsiadis, T., & Lendahl, U. (1996). Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development. Mechanisms of Development, 59(2), 177-190. DOI Scopus94 WoS93 Europe PMC71 |
1995 |
Dahlstrand, J., Lardelli, M., & Lendahl, U. (1995). Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system. Developmental Brain Research, 84(1), 109-129. DOI Scopus459 WoS427 Europe PMC341 |
1995 |
Mitsiadis, T. A., Lardelli, M., Lendahl, U., & Thesleff, I. (1995). Expression of Notch 1, 2, and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. Journal of Cell Biology, 130(2), 407-418. DOI Scopus157 WoS153 Europe PMC116 |
1995 |
Williams, R., Lendahl, U., & Lardelli, M. (1995). Complementary and combinatorial patterns of Notch gene family expression during early mouse development. Mechanisms of Development, 53(3), 357-368. DOI Scopus146 WoS146 Europe PMC100 |
1995 |
Lardelli, M. (1995). Residents’ rights. Nature, 378(6555), 330. DOI |
1995 |
Lardelli, M., Williams, R., & Lendahl, U. (1995). Notch-related genes in animal development. International Journal of Developmental Biology, 39(5), 769-780. Scopus51 WoS50 Europe PMC31 |
1995 |
Lardelli, M. (1995). Discriminatory frontier policy. Nature, 376(6535), 12. DOI |
1994 |
Lardelli, M., Dahlstrand, J., & Lendahl, U. (1994). The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mechanisms of Development, 46(2), 123-136. DOI Scopus271 WoS275 Europe PMC187 |
1994 |
Larsson, C., Lardelli, M., White, I., & Lendahl, U. (1994). The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation. Genomics, 24(2), 253-258. DOI Scopus87 WoS90 Europe PMC57 |
1994 |
Barlow, C., Meister, B., Lardelli, M., Lendahl, U., & Vennström, B. (1994). Thyroid abnormalities and hepatocellular carcinoma in mice transgenic for v-erbA. EMBO Journal, 13(18), 4241-4250. DOI Scopus77 WoS76 Europe PMC49 |
1994 |
Lardelli, M., & Lendahl, U. (1994). Generating bacteriophage λ sublibraries enriched for rare clones. BioTechniques, 16(3), 420-422. Scopus10 WoS10 Europe PMC7 |
1993 |
Lardelli, M., & Ish-Horowicz, D. (1993). Drosophila hairy pair-rule gene regulates embryonic patterning outside its apparent stripe domains. Development, 118(1), 255-266. DOI Scopus12 WoS12 Europe PMC9 |
1993 |
Lardelli, M., & Lendahl, U. (1993). Motch A and Motch B — Two mouse Notch homologues coexpressed in a wide variety of tissues. Experimental Cell Research, 204(2), 364-372. DOI Scopus125 WoS133 Europe PMC73 |
1989 |
Rushlow, C. A., Hogan, A., Pinchin, S. M., Howe, K. M., Lardelli, M., & Ish-Horowicz, D. (1989). The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N-myc.. The EMBO journal, 8(10), 3095-3103. DOI Scopus206 WoS232 Europe PMC134 |
1989 |
Johnson, M. A., Misra, R. M., Lardelli, M., Messina, M., Ephraums, C., Reeves, P. R., . . . Holmes, I. H. (1989). Synthesis in Escherichia coli of the major glycoprotein of human rotavirus: analysis of the antigenic regions. Gene, 84(1), 73-81. DOI Scopus10 WoS9 Europe PMC9 |