Karissa Barthelson

• Awards and Achievements

  Date	Type	Title	Institution Name	Country	Amount
  2021	Award	The Harold Woolhouse Prize	The University of Adelaide	Australia	$1000

• Education

  Date	Institution name	Country	Title
  2017 - 2021	University of Adelaide	Australia	Doctor of Philosophy
  2016 - 2016	University of Adelaide	Australia	Bachelor of Science (Hons)
  2010 - 2015	The University of Adelaide	Australia	Bachelor of Science

• Postgraduate Training

  Date	Title	Institution	Country
  2021 - 2022	Postdoctoral Research Officer	University of Adelaide	Australia

• Journals

  Year	Citation
  2024	Baer, L., Barthelson, K., Postlethwait, J. H., Adelson, D. L., Pederson, S. M., & Lardelli, M. (2024). Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis. PLoS Computational Biology, 20(2 February), e1011868. DOI
  2023	Baer, L., Barthelson, K., Postlethwait, J., Adelson, D., Pederson, S., & Lardelli, M. (2023). Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis. bioRxiv. DOI
  2023	Allen, A. G., Barthelson, K., & Lardelli, M. (2023). PHAPE: A plasmid for production of DNA size marker ladders for gel electrophoresis. Biology Methods and Protocols, 8(1), 8 pages. DOI
  2023	Gerken, E., Ahmad, S., Rattan, L., Hemsley, K., Barthelson, K., & Lardelli, M. (2023). Zebrafish models of Mucopolysaccharidosis types IIIA, B, & C show hyperactivity and changes in oligodendrocyte state. DOI
  2023	Lardelli, M., Baer, L., Hin, N., Allen, A., Pederson, S. M., & Barthelson, K. (2023). The Use of Zebrafish in Transcriptome Analysis of the Early Effects of Mutations Causing Early Onset Familial Alzheimer's Disease and Other Inherited Neurodegenerative Conditions.. Journal of Alzheimer's disease : JAD, 1-15. DOI
  2023	Barthelson, K., Hemsley, K., & Lardelli, M. (2023). Transcriptome analysis of early-onset familial Alzheimer’s disease and Sanfilippo syndrome zebrafish models reveals commonalities in disease mechanisms. DOI
  2022	Barthelson, K., Newman, M., & Lardelli, M. (2022). Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism. Disease Models and Mechanisms, 15(1), 1-14. DOI Scopus4 WoS1 Europe PMC2
  2021	Barthelson, K., Newman, M., & Lardelli, M. (2021). Comparative analysis of Alzheimer’s disease knock-in model brain transcriptomes implies changes to energy metabolism as a causative pathogenic stress. DOI
  2021	Dong, Y., Newman, M., Pederson, S. M., Barthelson, K., Hin, N., & Lardelli, M. (2021). Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer’s disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM functions, and iron homeostasis. BMC Genomics, 22(1), 211-1-211-16. DOI Scopus7 WoS6 Europe PMC5
  2021	Chin, H. Y., Lardelli, M., Collins-Praino, L., & Barthelson, K. (2021). Differential effects of loss of <i>park7</i> activity on Iron Responsive Element (IRE) gene sets: Implications for the role of iron dyshomeostasis in the pathophysiology of Parkinson’s disease. DOI
  2021	Barthelson, K., Pederson, S. M., Newman, M., Jiang, H., & Lardelli, M. (2021). In-Frame and Frameshift Mutations in Zebrafish Presenilin 2 Affect Different Cellular Functions in Young Adult Brains. Journal of Alzheimer's Disease Reports, 5(1), 395-404. DOI Scopus6 WoS5 Europe PMC6
  2021	Barthelson, K., Dong, Y., Newman, M., & Lardelli, M. (2021). PRESENILIN 1 mutations causing early-onset familial alzheimer's disease or familial acne inversa differ in their effects on genes facilitating energy metabolism and signal transduction. Journal of Alzheimers Disease, 82(1), 327-347. DOI Scopus4 WoS2 Europe PMC5
  2021	Chin, H. Y., Lardelli, M., Collins-Praino, L., & Barthelson, K. (2021). Loss of park7 activity has differential effects on expression of iron responsive element (IRE) gene sets in the brain transcriptome in a zebrafish model of Parkinson's disease.. Mol Brain, 14(1), 83. DOI Scopus7 WoS6 Europe PMC4
  2021	Barthelson, K., Baer, L., Dong, Y., Hand, M., Pujic, Z., Newman, M., . . . Lardelli, M. (2021). Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome. Frontiers in Genetics, 12, 1-11. DOI Scopus1 Europe PMC3
  2021	Barthelson, K., Pederson, S. M., Newman, M., & Lardelli, M. (2021). Brain transcriptome analysis of a protein-truncating mutation in sortilin-related receptor 1 associated with early-onset familial alzheimer's disease indicates early effects on mitochondrial and ribosome function. Journal of Alzheimer's Disease, 79(3), 1105-1119. DOI Scopus5 WoS4 Europe PMC5
  2021	Barthelson, K., Newman, M., Nowell, C. J., & Lardelli, M. (2021). No observed effect on brain vasculature of Alzheimer's disease-related mutations in the zebrafish presenilin 1 gene. Molecular Brain, 14(1), 22-1-22-4. DOI Scopus1 WoS1 Europe PMC1
  2021	Barthelson, K., Dong, Y., Newman, M., & Lardelli, M. (2021). <i>PRESENILIN 1</i>mutations causing early-onset familial Alzheimer’s disease or familial acne inversa differ in their effects on genes facilitating energy metabolism and signal transduction. DOI
  2020	Barthelson, K., Pederson, S. M., Newman, M., & Lardelli, M. (2020). Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease. biorxiv. DOI
  2020	Barthelson, K., Newman, M., & Lardelli, M. (2020). Sorting Out the Role of the Sortilin-Related Receptor 1 in Alzheimer's Disease. Journal of Alzheimer’s Disease Reports, 4(1), 123-140. DOI Scopus16 WoS13 Europe PMC11
  2020	Jiang, H., Pederson, S. M., Newman, M., Dong, Y., Barthelson, K., & Lardelli, M. (2020). Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2. PLoS One, 15(7), e0232559-1-e0232559-25. DOI Scopus4 WoS3 Europe PMC4
  2020	Barthelson, K., Pederson, S. M., Newman, M., & Lardelli, M. (2020). Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer's disease.. Molecular brain, 13(1), 142. DOI Scopus17 WoS14 Europe PMC14
  2020	Barthelson, K., Pederson, S., Newman, M., & Lardelli, M. (2020). Transcriptome analysis of a protein-truncating mutation in sortilin-related receptor 1 associated with early-onset familial Alzheimer’s disease indicates effects on mitochondrial and ribosome function in young-adult zebrafish brains. biorxiv. DOI
  2020	Barthelson, K., Pederson, S. M., Newman, M., Jiang, H., & Lardelli, M. (2020). Frameshift and frame-preserving mutations in zebrafish presenilin 2 affect different cellular functions in young adult brains. DOI

Genetics III

• Guest lecturer. 2018-2019, 2021.
• Practical Demonstrator. 2018-2021

Scientific Basis of Medicine II

• Tutor. 2021

• Current Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2024	Co-Supervisor	Creation & phenotypic characterisation of a novel zebrafish model of Zellweger syndrome, an untreatable peroxisomal disorder resulting in childhood dementia.	Doctor of Philosophy	Doctorate	Full Time	Mr Lakshay Rattan
  2023	Co-Supervisor	Investigating Early Molecular Drivers of Neurodegeneration by Modelling Parkinson's Disease in Zebrafish	Master of Philosophy	Master	Full Time	Miss Angel Grace Allen
  2022	Co-Supervisor	Investigating Alzheimer's disease and MPS III mutant gene using Zebrafish and Drosophila genetic models	Doctor of Philosophy	Doctorate	Full Time	Mr Kaijing Xu
  2022	Co-Supervisor	Molecular and bioinformatic studies of Alzheimer's and MPS III disease-linked genes in Zebrafish	Doctor of Philosophy	Doctorate	Full Time	Mr Ewan Gerken

• Email: karissa.barthelson@adelaide.edu.au