Dr Marina Kochetkova

Senior Research Fellow

Centre for Cancer Biology

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.


Year Citation
2025 Sorvina, A., Antoniou, M., Esmaeili, Z., & Kochetkova, M. (2025). Unusual Suspects: Bone and Cartilage ECM Proteins as Carcinoma Facilitators. Cancers, 15(3), 791-1-791-24.
DOI Scopus5 WoS3 Europe PMC2
2023 Clifton, G. T., Rothenberg, M., Ascierto, P. A., Begley, G., Cecchini, M., Eder, J. P., . . . Fridman, W. H. (2023). Developing a definition of immune exclusion in cancer: results of a modified Delphi workshop. Journal for ImmunoTherapy of Cancer, 11(6, article no. e006773), 1-8.
DOI Scopus20 WoS24 Europe PMC19
2022 Kochetkova, M., & Samuel, M. S. (2022). Differentiation of the tumor microenvironment: are CAFs the Organizer?. Trends in Cell Biology, 32(4), 285-294.
DOI Scopus48 WoS49 Europe PMC46
2021 Poltavets, V., Faulkner, J. W., Dhatrak, D., Whitfield, R. J., McColl, S. R., & Kochetkova, M. (2021). Cxcr4-ccr7 heterodimerization is a driver of breast cancer progression. Life, 11(10), 1-18.
DOI Scopus7 WoS6 Europe PMC5
2020 Boyle, S. T., Poltavets, V., Kular, J., Pyne, N. T., Sandow, J. J., Lewis, A. C., . . . Samuel, M. S. (2020). ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism. Nature Cell Biology, 22(7), 882-895.
DOI Scopus60 WoS60 Europe PMC56
2020 Whyte, C. E., Osman, M., Kara, E. E., Abbott, C., Foeng, J., McKenzie, D. R., . . . McColl, S. R. (2020). ACKR4 restrains antitumor immunity by regulating CCL21. Journal of Experimental Medicine, 217(6), 1-S4.
DOI Scopus29 WoS29 Europe PMC29
2020 Boyle, S. T., Poltavets, V., Kular, J., Pyne, N. T., Sandow, J. J., Lewis, A. C., . . . Samuel, M. S. (2020). Publisher Correction: ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism.. Nat Cell Biol, 22(7), 908.
DOI Scopus5 WoS4 Europe PMC6
2018 Xie, J., Shen, K., Lenchine, R., Gethings, L., Trim, P., Snel, M., . . . Proud, C. (2018). Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis. International Journal of Cancer, 142(9), 1865-1877.
DOI Scopus33 WoS34 Europe PMC32
2018 Poltavets, V., Kochetkova, M., Pitson, S. M., & Samuel, M. S. (2018). The role of the extracellular matrix and its molecular and cellular regulators in cancer cell plasticity. Frontiers in Oncology, 8(431), 431-1-431-19.
DOI Scopus311 WoS301 Europe PMC267
2017 Boyle, S., Gieniec, K., Gregor, C., Faulkner, J., McColl, S., & Kochetkova, M. (2017). Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells. Molecular Cancer, 16(1), 19-1-19-8.
DOI Scopus26 WoS27 Europe PMC22
2016 Samuel, M., Rath, N., Masre, S., Boyle, S., Greenhalgh, D., Kochetkova, M., . . . Olson, M. (2016). Tissue-selective expression of a conditionally-active ROCK2-estrogen receptor fusion protein. Genesis, 54(12), 636-646.
DOI Scopus10 WoS9 Europe PMC9
2016 Boyle, S., Ingman, W., Poltavets, V., Faulkner, J., Whitfield, R., McColl, S., & Kochetkova, M. (2016). The chemokine receptor CCR7 promotes mammary tumorigenesis through amplification of stem-like cells. Oncogene, 35(1), 105-115.
DOI Scopus33 WoS33 Europe PMC30
2015 Boyle, S., Faulkner, J., McColl, S., & Kochetkova, M. (2015). The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages. Molecular Cancer, 14(1), 115-1-115-14.
DOI Scopus51 WoS50 Europe PMC54
2014 Boyle, S. T., & Kochetkova, M. (2014). Breast cancer stem cells and the immune system: promotion, evasion and therapy. Journal of Mammary Gland Biology and Neoplasia, 19(2), 203-211.
DOI Scopus29 WoS29 Europe PMC21
2012 Brazzatti, J., Klingler-Hoffmann, M., Haylock-Jacobs, S., Harata-Lee, Y., Niu, M., Higgins, M., . . . McColl, S. (2012). Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis. Oncogene, 31(18), 2350-2361.
DOI Scopus48 WoS46 Europe PMC45
2012 Wendel, C., Hemping-Bovenkerk, A., Krasnyanska, J., Mees, S., Kochetkova, M., Stoeppeler, S., & Haier, J. (2012). CXCR4/CXCL12 participate in extravasation of metastasizing breast cancer cells within the liver in a rat model. PLoS One, 7(1), 1-13.
DOI Scopus68 WoS64 Europe PMC56
2009 Kochetkova, M., Kumar, S., & McColl, S. (2009). Chemokine receptors CXCR4 and CCR7 promote metastasis by preventing anoikis in cancer cells. Cell Death and Differentiation, 16(5), 664-673.
DOI Scopus87 WoS83 Europe PMC74
2006 Holland, J., Kochetkova, M., Akekawatchai, C., Dottore, M., Lopez, A., & McColl, S. (2006). Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells. Cancer Research, 66(8), 4117-4124.
DOI Scopus85 WoS83 Europe PMC76
2005 Akekawatchai, C., Holland, J., Kochetkova, M., Wallace, J., & McColl, S. (2005). Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells. Journal of Biological Chemistry, 280(48), 39701-39708.
DOI Scopus95 WoS90 Europe PMC78
2002 Powell, J., Gardner, A., Bais, A., Hinze, S., Baker, E., Whitmore, S., . . . Kremmidiotis, G. (2002). Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes. Genomics, 80(3), 303-310.
DOI Scopus41 WoS41 Europe PMC34
2002 Kochetkova, M., McKenzie, O., Bais, A., Martin, J., Secker, G., Seshadri, R., . . . Callen, D. (2002). CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3. Cancer Research, 62(16), 4599-4604.
Scopus62 WoS61 Europe PMC52
1997 Kocketkova, M., Iversen, P., Lopez, A., & Shannon, M. (1997). Deoxyribo-nucleic acid triplex formation inhibits granulocyte-macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells.. Journal of Clinical Investigation, 99(12), 3000-3008.
DOI Scopus47 WoS45 Europe PMC30
  • Stopping breast cancer progression by targeting tumour stroma, NHMRC - Ideas Grants, 01/01/2021 - 31/12/2024

  • Repurposing the Field Effect to understand epigenetic control of the microenvironment, NHMRC - Ideas Grants, 01/01/2020 - 31/12/2022

Date Role Research Topic Program Degree Type Student Load Student Name
2025 External Supervisor Investigating epigenetically regulated CAF conversion to the pro-malignant state in early-stage oral tongue squamous cell carcinoma Doctor of Philosophy Doctorate Full Time Miss Di Jiang
2025 External Supervisor Investigating epigenetically regulated CAF conversion to the pro-malignant state in early-stage oral tongue squamous cell carcinoma Doctor of Philosophy Doctorate Full Time Miss Di Jiang
2023 External Supervisor How Cancer Associated Fibroblasts Modify Stromal Landscape to Advance Malignant Progression of Breast Cancer Doctor of Philosophy Doctorate Full Time Mr Michael Antoniou
2023 External Supervisor Immunological determinants of head and neck cancer progression and metastasis, in particular the role of cancer associated fibroblasts Master of Philosophy (Surgery) Master Part Time Miss Laura Kenyon
2023 External Supervisor Immunological determinants of head and neck cancer progression and metastasis, in particular the role of cancer associated fibroblasts Master of Research Master Full Time Miss Laura Kenyon
2022 External Supervisor Tumour stroma characteristics as new modality for breast cancer diagnosis and treatment. Master of Philosophy (Surgery) Master Part Time Miss Ngoc Hoang Ha
2022 External Supervisor Tumour stroma characteristics as new modality for breast cancer diagnosis and treatment. Master of Research Master Full Time Miss Ngoc Hoang Ha

Date Role Research Topic Program Degree Type Student Load Student Name
2012 - 2015 Co-Supervisor The Role of Chemokine Receptors CCR6 and CCR7 in the Initiation and Progression of Breast Cancer Doctor of Philosophy Doctorate Full Time Dr Sarah Theresa Boyle
2003 - 2007 Co-Supervisor The Role of Chemokine Receptors in Breast Cancer Metastasis Doctor of Philosophy Doctorate Full Time Miss Jane Holland

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