Lukas Gerstweiler
School of Chemical Engineering and Advanced Materials
Faculty of Sciences, Engineering and Technology
I am interested in the efficient production and purification of biomolecules and novel therapeutics, such as vaccines, virus-like particles, mRNA/DNA and antibodies. My research concentrates on process intensification and the transition from batch to continuous manufacturing applying continuous multi-column chromatography systems and advanced process integration strategies. Another research field is in-silico simulation of chromatography for process development and up-scaling, and advanced control strategies using artificial intelligence
-
Appointments
Date Position Institution name 2022 - ongoing Lecturer The University of Adelaide 2017 - 2017 Intern Bardehle & Pagenberg 2016 - 2017 Student assistant Fraunhofer Institute for Process Engineering and Packaging -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review German Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title University of Hohenheim Germany Bc. Sc. Food Science and Biotechnology Technical University Munich Germany M.Sc. Pharmaceutical Bioprocess Engineering -
Research Interests
-
Journals
Year Citation 2022 Gerstweiler, L., Billakanti, J., Bi, J., & Middelberg, A. P. J. (2022). Control strategy for multi-column continuous periodic counter current chromatography subject to fluctuating inlet stream concentration. Journal of Chromatography A, 1667, 8 pages.
Scopus1 WoS12022 Gerstweiler, L., Billakanti, J., Bi, J., & Middelberg, A. P. J. (2022). An integrated and continuous downstream process for microbial virus-like particle vaccine biomanufacture. Biotechnology and Bioengineering, 12 pages.
2021 Gerstweiler, L., Billakanti, J., Bi, J., & Middelberg, A. (2021). Comparative evaluation of integrated purification pathways for bacterial modular polyomavirus major capsid protein VP1 to produce virus-like particles using high throughput process technologies. Journal of Chromatography A, 1639, 1-11.
Scopus2 WoS22021 Gerstweiler, L., Bi, J., & Middelberg, A. (2021). Virus‐like particle preparation is improved by control over capsomere‐DNA interactions during chromatographic purification. Biotechnology and Bioengineering, 118(4), 1688-1701.
Scopus4 WoS5 Europe PMC22021 Gerstweiler, L., Bi, J., & Middelberg, A. P. J. (2021). Front Cover Image, Volume 118, Number 4, April 2021. Biotechnology and Bioengineering, 118(4).
2020 Gerstweiler, L., Bi, J., & Middelberg, A. P. J. (2020). Continuous downstream bioprocessing for intensified manufacture of biopharmaceuticals and antibodies. Chemical Engineering Science, 231, 1-17.
Scopus7 WoS5
CHEM ENG 7065 - Batch and Continuous Biomanufacturing
CHEM ENG 4074 - Brewery Engineering
CHEM ENG 2073 - Food Engineering
BIOTECH 3000 - Biotechnology Practice III
Connect With Me
External Profiles
