Welcome to the captivating world of biomanufacturing research, where cutting-edge scientific breakthroughs are transforming the way we produce life-saving therapeutics, revolutionary protein-based foods, and next-generation vaccines. As a lecturer at The University of Adelaide, I am dedicated to exploring and advancing the frontiers of continuous biomanufacturing, downstream processing, chromatography, and virus-like particle (VLP) technology. In this brief overview, I will introduce you to my research interests and shed light on the exciting possibilities that lie ahead.

Please also check out our biomanufacturing research group page

Continuous Biomanufacturing and Process Intensification:

At the forefront of my research lies the development and optimization of continuous biomanufacturing processes. By moving away from traditional batch-based methods, we are pioneering integrated manufacturing approaches that facilitate the streamlined production of biotherapeutics, recombinant proteins, mRNA-based medicines, and even recombinant food proteins. By enhancing process efficiency, reducing costs, and ensuring consistent quality, continuous biomanufacturing holds immense potential to revolutionize the healthcare and food industries.

Downstream Processing and Chromatography Innovations:

In the pursuit of efficient and sustainable biomanufacturing, my research delves into downstream processing and chromatography, a critical step in isolating and purifying biotherapeutics and proteins. A particular focus of my work revolves around novel resin materials based on porous co-polymers. These advanced materials offer increased selectivity, improved separation capabilities, and enhanced productivity, paving the way for more efficient and environmentally friendly purification processes.

Mechanistic Modeling and Process Optimization:

To optimize chromatographic purification and overcome the challenges posed by complex biomolecules, my research incorporates mechanistic modeling techniques. By employing computational approaches and mathematical modeling, we gain valuable insights into the intricate interactions between biomolecules and chromatographic systems. This deeper understanding enables us to fine-tune purification processes, maximize product yield, minimize production costs, and accelerate the delivery of life-saving therapies to patients worldwide.

Virus-Like Particle (VLP) Technology and Vaccine Platforms:

Viruses have long been a significant challenge in public health, but they also offer a unique opportunity to harness their structural properties for novel vaccine development. My research explores the manufacturing of Virus-Like Particles (VLPs) and the creation of innovative VLP-based vaccine platforms. By leveraging the self-assembling nature of VLPs, we aim to engineer safe and effective vaccines against a wide range of diseases, including those caused by emerging pathogens. These breakthroughs hold promise for providing rapid responses to pandemics and protecting global health.

Future Perspectives:

As we move forward, my research group seeks to collaborate with motivated students and researchers who share our passion for biomanufacturing advancements. Through our multidisciplinary approach, we aim to integrate engineering, biology, and computational sciences to drive transformative innovations. Our overarching goal is to contribute to a future where life-saving medicines are more accessible, sustainable protein production is realized, and global health threats are effectively addressed.