Ivan Kempson

Prof Ivan Kempson

Associate Professor of Biophysics

Future Industries Institute

Future Industries Institute

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Available For Media Comment.

I have a background in physics which has evolved into fields of bio-inorganic chemistry and surface science. This has been motivated by applying physical-chemistry concepts and characterization tools to areas of nanotechnology, biotechnology and pharmaceutical sciences.
These interests are being used to develop improvements in understanding disease, therapeutic delivery and pharmaceutical products and novel methodologies for extracting quantitative metrics in determining relevant parameters. This has been a balance between basic and applied research with interest in clinical developments for human health and engaging pharma industries.
My research has been highly multidisciplinary and incorporated strong collaborations world wide for which I have greatly enjoyed the cultural exchange as well as exposure to exceptional research. I have conducted research in the USA, Canada, Japan, England, The Netherlands, Taiwan and China. I have been the recipient of 5 visiting scholar positions in Canada (the Canadian Light Source and Western University), Taiwan (Institute of Physics, Academia Sinica) and China (Institute of Chemistry, Chinese Academy of Sciences).
I enjoy seeing my research published in high impact journals such as Angewandte Chemie, Small, Chemical Society Reviews, Advanced Materials, the Journal of Controlled Release etc. All up I have over 50 publications including 3 invited book chapters. These are giving rise to rapidly growing citations and an h-index of 19 by PubMed.
Exposure of my work has been given by presentation at over 70 international conference presentations. It is especially recognised by delivering 16 international invited and keynote talks in 8 different countries. The general significance is also demonstrated by being invited twice to represent Australia at the International Atomic Energy Agency (IAEA) technical meetings at the UN headquarters in Vienna, Austria.
Other community duties include:

Editor for Nature Publishing Group’s Scientific Reports
Reviewing for over 30 journals
Reviewing of research grant applications in 5 countries
Member of the Program Advisory Committee for X-ray Fluorescence Microscopy at the Australian Synchrotron 
The Australian representative in the IAEA Collaborative Research Program for X-ray fluorescence at the Elettra Synchrotron, Trieste, Italy
I am the first ever foreign recipient of a certificate in recognition of my work for the Supreme Public Prosecutors Office in Taiwan

  • Nanomedicine
  • Radiosensitization
  • Pharmaceutical surface analysis in relation to product attributes (solid form and biologicals)
  • Biological imaging for heterogeneity in nanoparticle delivery to tumour, nanoparticle fate and nanoparticle contrast agents
  • Stimuli responsive carriers for drug delivery
  • Tumour sensitization for radiotherapies (via gene therapy and nanoparticle-radiation interactions)
  • Trace Analysis and biomonitoring with particular respect to inorganic toxicology
  • Nanoparticle toxicity and fate

Year Citation
2025 Atkinson, J., Chopin, J., Bezak, E., Le, H., & Kempson, I. (2025). Gold nanoparticles cause radiosensitization in 4T1 cells by inhibiting DNA double strand break repair: single cell comparisons of DSB formation and γH2AX expression. ChemPhysChem, 26(3, article no. e202400764), 1-9.
DOI Scopus2 WoS2 Europe PMC1
2025 Yang, C. T., Cho, I. C., Yu, C. F., Cheah, E., Liu, T., Lin, Y. P., . . . Thierry, B. (2025). 3D printed microtissue cassettes enabling high throughput proton radiobiological assays. Analytica Chimica Acta, 1356(344027), 1-7.
DOI
2025 Sailo, B. L., Garhwal, A., Mishra, A., Hegde, M., Vishwa, R., Girisa, S., . . . Kunnumakkara, A. B. (2025). Potential of capsaicin as a combinatorial agent to overcome chemoresistance and to improve outcomes of cancer therapy. Biochemical Pharmacology, 236(116828), 16 pages.
DOI Scopus4 WoS3
2025 Liang, S., Van-Chanh Le, Q., Arrua, R. D., Turnbull, T., & Kempson, I. (2025). Improved Control of Triple-Negative Breast Cancer Tumor and Metastasis with a pH-Sensitive Hyaluronic Acid Nanocarrier for Doxorubicin Delivery. ACS Biomaterials Science and Engineering, 11(1), 623-633.
DOI Scopus2 WoS2 Europe PMC2
2024 Ghasemi, M., Holmes, A., Turnbull, T., & Kempson, I. (2024). Gold Nanoparticle Detection with Two-Photon Excitation Fluorescence Lifetime Imaging of NAD(P)H in Cancer Cells: An Analytical Approach to Separate Nanoparticle and NAD(P)H Signals. Analytical Chemistry, 96(52), 20435-20444.
DOI Scopus1 WoS1 Europe PMC1
2024 Ou, D. L., Liao, Z. X., Kempson, I. M., Li, L., Yang, P. C., & Tseng, S. J. (2024). Nano-modified viruses prime the tumor microenvironment and promote the photodynamic virotherapy in liver cancer. Journal of Biomedical Science, 31(1), 12 pages.
DOI Scopus12 WoS11 Europe PMC11
2024 Atkinson, J., Bezak, E., Le, H., & Kempson, I. (2024). DNA Double strand break and response fluorescent assays: choices and interpretation. International Journal of Molecular Sciences, 25(4, article no. 2227), 1-27.
DOI Scopus15 WoS13 Europe PMC14
2024 Howard, D., Turnbull, T., Wilson, P., Paterson, D. J., Milanova, V., Thierry, B., & Kempson, I. (2024). Quantitative Single-Cell Comparison of Sensitization to Radiation and a Radiomimetic Drug for Diverse Gold Nanoparticle Coatings. Small Science, 4(9), 13 pages.
DOI Scopus3 WoS4 Europe PMC2
2023 Atkinson, J., Bezak, E., Le, H., & Kempson, I. (2023). The current status of FLASH particle therapy: a systematic review. Physical and Engineering Sciences in Medicine, 46(2), 529-560.
DOI Scopus33 WoS30 Europe PMC14
2023 Sebastian, S., Hoffmann, M. K., Howard, D., Young, C., Washington, J., Unterweger, H., . . . Kempson, I. (2023). Kinetic effects of transferrin-conjugated gold nanoparticles on the antioxidant glutathione-thioredoxin pathway. Antioxidants, 12(8, article no. 1617), 1-21.
DOI Scopus8 WoS8 Europe PMC7
2023 Liao, Z. X., Hsu, S. H., Tang, S. C., Kempson, I., Yang, P. C., & Tseng, S. J. (2023). Potential targeting of the tumor microenvironment to improve cancer virotherapy. Pharmacology and Therapeutics, 250(108521), 11 pages.
DOI Scopus18 WoS15 Europe PMC10
2022 Dehghankelishadi, P., Maritz, M. F., Dmochowska, N., Badiee, P., Cheah, E., Kempson, I., . . . Thierry, B. (2022). Formulation of simvastatin within high density lipoprotein enables potent tumour radiosensitisation. Journal of Controlled Release, 346, 98-109.
DOI Scopus20 WoS17 Europe PMC11
2022 Nazarizadeh, A., Staudacher, A. H., Wittwer, N. L., Turnbull, T., Brown, M. P., & Kempson, I. (2022). Aluminium Nanoparticles as Efficient Adjuvants Compared to Their Microparticle Counterparts: Current Progress and Perspectives. International Journal of Molecular Sciences, 23(9), 4707-1-4707-15.
DOI Scopus36 WoS32 Europe PMC26
2022 Atkinson, J., Bezak, E., & Kempson, I. (2022). Imaging DNA double-strand breaks - are we there yet?. Nature Reviews Molecular Cell Biology, 23(9), 579-580.
DOI Scopus12 WoS11 Europe PMC11
2022 Howard, D., Turnbull, T., Paterson, D. J., Thierry, B., & Kempson, I. (2022). Cell Size as a Primary Determinant in Targeted Nanoparticle Uptake. ACS Applied Bio Materials, 5(9), 4222-4231.
DOI Scopus7 WoS6 Europe PMC3
2022 Kempson, I. (2022). Nanoparticle-Based Radiosensitization. International Journal of Molecular Sciences, 23(9), 3 pages.
DOI Scopus4 WoS4 Europe PMC4
2022 Tseng, S. J., Kempson, I. M., Liao, Z. X., Ho, Y. C., & Yang, P. C. (2022). Corrigendum to “An acid degradable, lactate oxidizing nanoparticle formulation for non-small cell lung cancer virotherapy” Nano Today 46 (2022) 101582 (Nano Today (2022) 46, (S1748013222002109), (10.1016/j.nantod.2022.101582)). Nano Today, 47, 3 pages.
DOI
2022 Tseng, S. J., Kempson, I. M., Liao, Z. X., Ho, Y. C., & Yang, P. C. (2022). An acid degradable, lactate oxidizing nanoparticle formulation for non-small cell lung cancer virotherapy. Nano Today, 46(101582), 10 pages.
DOI Scopus24 WoS22
2021 Ou, D. L., Tseng, S. J., Kempson, I. M., Hsu, C. L., Yang, P. C., & Liao, Z. X. (2021). Enhanced Targeting and Immune Activation of Tumor Microenvironment by Nanomodified Anti-PD1 in Liver Cancer. Advanced Therapeutics, 4(6), 8 pages.
DOI Scopus14 WoS13
2021 Ghasemi, M., Turnbull, T., Sebastian, S., & Kempson, I. (2021). The mtt assay: Utility, limitations, pitfalls, and interpretation in bulk and single-cell analysis. International Journal of Molecular Sciences, 22(23), 30 pages.
DOI Scopus879 WoS773 Europe PMC519
2021 Liao, Z. X., Kempson, I. M., Hsieh, C. C., Tseng, S. J., & Yang, P. C. (2021). Potential therapeutics using tumor-secreted lactate in nonsmall cell lung cancer. Drug Discovery Today, 26(11), 2508-2514.
DOI Scopus37 WoS35 Europe PMC28
2021 Kempson, I. (2021). Mechanisms of nanoparticle radiosensitization. Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, 13(1), 19 pages.
DOI Scopus68 WoS65 Europe PMC41
2021 Huynh, M., Kempson, I., Bezak, E., & Phillips, W. (2021). Predictive modeling of hypoxic head and neck cancers during fractionated radiotherapy with gold nanoparticle radiosensitization. Medical Physics, 48(6), 3120-3133.
DOI Scopus10 WoS10 Europe PMC9
2020 Peukert, D., Kempson, I., Douglass, M., & Bezak, E. (2020). Gold nanoparticle enhanced proton therapy: A Monte Carlo simulation of the effects of proton energy, nanoparticle size, coating material and coating thickness on dose and radiolysis yield.. Medical physics, 47(2), 651-661.
DOI Scopus38 WoS36 Europe PMC23
2020 Peukert, D., Kempson, I., Douglass, M., & Bezak, E. (2020). Modelling Spatial Scales of Dose Deposition and Radiolysis Products from Gold Nanoparticle Sensitisation of Proton Therapy in A Cell: From Intracellular Structures to Adjacent Cells.. Int J Mol Sci, 21(12), 1-19.
DOI Scopus7 WoS7 Europe PMC4
2020 Huynh, M., Kempson, I., Bezak, E., & Phillips, W. (2020). In silico modeling of cellular probabilistic nanoparticle radiosensitization in head and neck cancers. Nanomedicine, 15(29), 2837-2850.
DOI Scopus3 WoS3 Europe PMC3
2020 Sepand, M. R., Ranjbar, S., Kempson, I. M., Akbariani, M., Muganda, W. C. A., Müller, M., . . . Raoufi, M. (2020). Targeting non-apoptotic cell death in cancer treatment by nanomaterials: Recent advances and future outlook. Nanomedicine Nanotechnology Biology and Medicine, 29(102243), 20 pages.
DOI Scopus41 WoS35 Europe PMC19
2020 Holmes, A. M., Kempson, I., Turnbull, T., Paterson, D., & Roberts, M. S. (2020). Penetration of Zinc into Human Skin after Topical Application of Nano Zinc Oxide Used in Commercial Sunscreen Formulations. ACS Applied Bio Materials, 3(6), 3640-3647.
DOI Scopus37 WoS34 Europe PMC19
2020 Liao, Z. X., Huang, K. Y., Kempson, I. M., Li, H. J., Tseng, S. J., & Yang, P. C. (2020). Nanomodified strategies to overcome EGFR-tyrosine kinase inhibitors resistance in non-small cell lung cancer. Journal of Controlled Release, 324, 482-492.
DOI Scopus21 WoS19 Europe PMC13
2020 Kempson, I. (2020). Nanoparticle-based radiosensitization. International Journal of Molecular Sciences, 21(8), 3 pages.
DOI Scopus6 WoS7 Europe PMC2
2020 Howard, D., Sebastian, S., Le, Q. V. C., Thierry, B., & Kempson, I. (2020). Chemical mechanisms of nanoparticle radiosensitization and radioprotection: A review of structure-function relationships influencing reactive oxygen species. International Journal of Molecular Sciences, 21(2), 23 pages.
DOI Scopus92 WoS89 Europe PMC64
2019 Turnbull, T., Thierry, B., & Kempson, I. (2019). A quantitative study of intercellular heterogeneity in gold nanoparticle uptake across multiple cell lines. Analytical and Bioanalytical Chemistry, 411(28), 7529-7538.
DOI Scopus14 WoS13 Europe PMC11
2019 Liao, Z. X., Fa, Y. C., Kempson, I. M., & Tseng, S. J. (2019). Repolarization of M2 to M1 Macrophages Triggered by Lactate Oxidase Released from Methylcellulose Hydrogel. Bioconjugate Chemistry, 30(10), 2697-2702.
DOI Scopus41 WoS38 Europe PMC30
2019 Guo, Z., Yang, C. T., Maritz, M. F., Wu, H., Wilson, P., Warkiani, M. E., . . . Thierry, B. (2019). Validation of a Vasculogenesis Microfluidic Model for Radiobiological Studies of the Human Microvasculature. Advanced Materials Technologies, 4(4), 12 pages.
DOI Scopus33 WoS28
2019 Peukert, D., Incerti, S., Kempson, I., Douglass, M., Karamitros, M., Baldacchino, G., & Bezak, E. (2019). Validation and investigation of reactive species yields of Geant4-DNA chemistry models. Medical Physics, 46(2), 983-998.
DOI Scopus26 WoS26 Europe PMC18
2019 Kaur, S., Law, C. S., Williamson, N. H., Kempson, I., Popat, A., Kumeria, T., & Santos, A. (2019). Environmental copper sensor based on polyethylenimine-functionalized nanoporous anodic alumina interferometers. Analytical Chemistry, 91(8), 5011-5020.
DOI Scopus55 WoS51 Europe PMC19
2019 Turnbull, T., Douglass, M., Williamson, N. H., Howard, D., Bhardwaj, R., Lawrence, M., . . . Kempson, I. M. (2019). Cross-correlative single-cell analysis reveals biological mechanisms of nanoparticle radiosensitization. ACS Nano, 13(5), 5077-5090.
DOI Scopus49 WoS50 Europe PMC37
2019 Dylan, P., Kempson, I., Douglass, M., & Bezak, E. (2019). Gold Nanoparticle Enhanced Proton Therapy: Monte Carlo Modeling of Reactive Species' Distributions Around a Gold Nanoparticle and the Effects of Nanoparticle Proximity and Clustering. International Journal of Molecular Sciences, 20(17), 1-22.
DOI Scopus37 WoS33 Europe PMC25
2018 Peukert, D., Kempson, I., Douglass, M., & Bezak, E. (2018). Metallic nanoparticle radiosensitisation of ion radiotherapy: a review. Physica Medica, 47, 121-128.
DOI Scopus63 WoS51 Europe PMC33
2018 Kaur, S., Kempson, I., Xu, H., Nyden, M., & Larsson, M. (2018). Bio-template assisted synthesis of porous glutaraldehyde-polyethyleneimine particulate resin for selective copper ion binding and recovery. RSC ADVANCES, 8(22), 12043-12052.
DOI Scopus12 WoS12 Europe PMC5
2018 Tseng, S. J., Kempson, I. M., Huang, K. Y., Li, H. J., Fa, Y. C., Ho, Y. C., . . . Yang, P. C. (2018). Targeting Tumor Microenvironment by Bioreduction-Activated Nanoparticles for Light-Triggered Virotherapy. ACS Nano, 12(10), 9894-9902.
DOI Scopus75 WoS73 Europe PMC50
2018 Liao, Z. X., Kempson, I. M., Fa, Y. C., Liu, M. C., Hsieh, L. C., Huang, K. Y., & Wang, L. F. (2018). Correction: Magnetically guided viral transduction of gene-based sensitization for localized photodynamic therapy to overcome multidrug resistance in breast cancer cells (Bioconjugate Chemistry (2017) 28:6 (1702-1708) DOI: 10.1021/acs.bioconjchem.7b00162). Bioconjugate Chemistry, 29(6), 2126.
DOI Scopus1 WoS1 Europe PMC1
2018 Holmes, A. M., Kempson, I., Turnbull, T., Paterson, D., & Roberts, M. S. (2018). Imaging the penetration and distribution of zinc and zinc species after topical application of zinc pyrithione to human skin. Toxicology and Applied Pharmacology, 343, 40-47.
DOI Scopus23 WoS19 Europe PMC13
2018 Liao, Z. X., Kempson, I. M., Chen, M. J., Fa, Y. C., Huang, K. Y., & Wang, L. F. (2018). Micro-scale RNA Interference using Iron Oxide Nanoparticle-modified Lentivirus. Chemnanomat, 4(1), 98-102.
DOI Scopus7 WoS7
2017 Liao, Z. X., Liu, M. C., Kempson, I. M., Fa, Y. C., & Huang, K. Y. (2017). Light-triggered methylcellulose gold nanoparticle hydrogels for leptin release to inhibit fat stores in adipocytes. International Journal of Nanomedicine, 12, 7603-7611.
DOI Scopus16 WoS14 Europe PMC9
2017 Liao, Z. X., Kempson, I. M., Fa, Y. C., Liu, M. C., Hsieh, L. C., Huang, K. Y., & Wang, L. F. (2017). Magnetically Guided Viral Transduction of Gene-Based Sensitization for Localized Photodynamic Therapy to Overcome Multidrug Resistance in Breast Cancer Cells. Bioconjugate Chemistry, 28(6), 1702-1708.
DOI Scopus13 WoS13 Europe PMC10
2017 Kaur, S., Kempson, I. M., Lindén, J. B., Larsson, M., & Nydén, M. (2017). Unhindered copper uptake by glutaraldehyde-polyethyleneimine coatings in an artificial seawater model system with adsorbed swollen polysaccharides and competing ligand EDTA. Biofouling, 33(2), 184-194.
DOI Scopus10 WoS9 Europe PMC3
2017 Larsson, M., Lindén, J. B., Kaur, S., Le Cerf, B., & Kempson, I. (2017). Cu K-edge XANES: polymer, organic, inorganic spectra, and experimental considerations. Powder diffraction, 32(2), 28-32.
DOI Scopus11 WoS11
2017 Turnbull, T., Douglass, M., Bezak, E., Thierry, B., & Kempson, I. (2017). An image processing application for quantitative cross-correlative microscopy for large cell-populations: a gold nanoparticle radiosensitisation study. Powder Diffraction, 32(S2), S33-S37.
DOI Scopus2 WoS2
2016 Tseng, S. J., Huang, K. Y., Kempson, I. M., Kao, S. H., Liu, M. C., Yang, S. C., . . . Yang, P. C. (2016). Remote Control of Light-Triggered Virotherapy. ACS Nano, 10(11), 10339-10346.
DOI Scopus39 WoS35 Europe PMC28
2016 Joyce, P., Kempson, I., & Prestidge, C. A. (2016). Orientating lipase molecules through surface chemical control for enhanced activity: A QCM-D and ToF-SIMS investigation. Colloids and Surfaces B Biointerfaces, 142, 173-181.
DOI Scopus32 WoS30 Europe PMC16
2015 Kao, S. H., Huang, K. Y., Li, H. J., Tseng, S. J., Liao, Z. X., & Kempson, I. (2015). Erratum: Environmental pH-sensitive polymeric nano-carriers for targeted tumor delivery (J. Control. Release (2015) 213 (e46-e47) DOI: 10.1016/j.jconrel.2015.05.075 PII: S0168365915003739). Journal of Controlled Release, 218, 1.
DOI
2015 Joyce, P., Kempson, I., & Prestidge, C. A. (2015). QCM-D and ToF-SIMS Investigation to Deconvolute the Relationship between Lipid Adsorption and Orientation on Lipase Activity. Langmuir, 31(37), 10198-10207.
DOI Scopus25 WoS25 Europe PMC14
2015 Tseng, S. J., Liao, Z. X., Kao, S. H., Zeng, Y. F., Huang, K. Y., Li, H. J., . . . Kempson, I. M. (2015). Highly specific in vivo gene delivery for p53-mediated apoptosis and genetic photodynamic therapies of tumour. Nature Communications, 6(1), 10 pages.
DOI Scopus99 WoS98 Europe PMC73
2015 Kao, S. -H., Huang, K. -Y., Li, H. -J., Tseng, S. -J., Liao, Z. -X., & Kempson, I. (2015). Environmental pH-sensitive polymeric nano-carriers for targeted tumor delivery. JOURNAL OF CONTROLLED RELEASE, 213, E46-E47.
DOI WoS1
2015 Turnbull, T., Douglass, M., Paterson, D., Bezak, E., Thierry, B., & Kempson, I. (2015). Relating intercellular variability in nanoparticle uptake with biological consequence: a quantitative x-ray fluorescence study for radiosensitization of cells. Analytical Chemistry, 87(21), 10693-10697.
DOI Scopus14 WoS13 Europe PMC7
2015 Lindén, J. B., Larsson, M., Kaur, S., Skinner, W. M., Miklavcic, S. J., Nann, T., . . . Nydén, M. (2015). Polyethyleneimine for copper absorption II: kinetics, selectivity and efficiency from seawater. Rsc Advances, 5(64), 51883-51890.
DOI Scopus64 WoS62
2014 Aboh, I. K., Eichert, D., Euaruksakul, C., Fazinic, S., Kempson, I. M., Musa, M. A., & Voutchkov, M. K. (2014). IAEA Technical Meeting on 'The advanced analytical techniques for Laboratory and Industralia applications' - TM-42953, 24-28 September 2012. XRF Newsletter.
2014 Kempson, I., Smith, E., Gao, M., De Jonge, M., & Thierry, B. (2014). Large area synchrotron X-ray fluorescence mapping of biological samples. Journal of Instrumentation, 9(12), 6 pages.
DOI Scopus4 WoS6
2014 Jing, L., Ding, K., Kershaw, S. V., Kempson, I. M., Rogach, A. L., & Gao, M. (2014). Magnetically Engineered Semiconductor Quantum Dots as Multimodal Imaging Probes. Advanced Materials, 26(37), 6367-6386.
DOI Scopus152 WoS142 Europe PMC76
2014 Sun, X., Wang, B., Kempson, I., Liu, C., Hou, Y., & Gao, M. (2014). Restructuring and remodeling of NaREF 4 nanocrystals by electron irradiation. Small, 10(22), 4711-4717.
DOI Scopus28 WoS27 Europe PMC13
2014 Liu, T., Kempson, I., De Jonge, M., Howard, D. L., & Thierry, B. (2014). Quantitative synchrotron X-ray fluorescence study of the penetration of transferrin-conjugated gold nanoparticles inside model tumour tissues. Nanoscale, 6(16), 9774-9782.
DOI Scopus34 WoS32 Europe PMC15
2013 Kempson, I. M., Chang, P., Bremmell, K., & Prestidge, C. A. (2013). Low temperature thermal dependent filgrastim adsorption behavior detected with ToF-SIMS. Langmuir, 29(50), 15573-15578.
DOI Scopus9 WoS10 Europe PMC6
2013 Liu, T., Cousins, A., Chien, C., Kempson, I., Thompson, S., Hwu, Y., & Thierry, B. (2013). Immunospecific targeting of CD45 expressing lymphoid cells: Towards improved detection agents of the sentinel lymph node. Cancer Letters, 328(2), 271-277.
DOI Scopus13 WoS12 Europe PMC7
2013 Chien, C. C., Kempson, I. M., Wang, C. L., Chen, H. H., Hwu, Y., Chen, N. Y., . . . Margaritondo, G. (2013). Complete microscale profiling of tumor microangiogenesis. A microradiological methodology reveals fundamental aspects of tumor angiogenesis and yields an array of quantitative parameters for its characterization.. Biotechnology advances, 31(3), 396-401.
DOI Scopus9 WoS11 Europe PMC8
2013 Tseng, S. J., Kempson, I. M., Peng, S. F., Ke, B. H., Chen, H. H., Chen, P. F., & Hwu, Y. (2013). Environment acidity triggers release of recombinant adeno-associated virus serotype 2 from a tunable matrix. Journal of Controlled Release, 170(2), 252-258.
DOI Scopus20 WoS21 Europe PMC16
2013 Tung, H. T., Chen, I. G., Song, J. M., Tsai, M. G., Kempson, I. M., Margaritondo, G., & Hwu, Y. (2013). Cu(In1-xGax)S2 nanocrystals and films: Low-temperature synthesis with size and composition control. Nanoscale, 5(11), 4706-4710.
DOI Scopus10 WoS10
2013 Lin, C. W., Tseng, S. J., Kempson, I. M., Yang, S. C., Hong, T. M., & Yang, P. C. (2013). Extracellular delivery of modified oligonucleotide and superparamagnetic iron oxide nanoparticles from a degradable hydrogel triggered by tumor acidosis. Biomaterials, 34(17), 4387-4393.
DOI Scopus40 WoS39 Europe PMC29
2013 Tseng, S. J., Zeng, Y. F., Deng, Y. F., Yang, P. C., Liu, J. R., & Kempson, I. M. (2013). Switchable delivery of small interfering RNA using a negatively charged pH-responsive polyethylenimine-based polyelectrolyte complex. Chemical Communications, 49(26), 2670-2672.
DOI Scopus25 WoS22 Europe PMC16
2012 Kempson, I. M., Chien, C. C., Chung, C. Y., Hwu, Y., Paterson, D., de Jonge, M. D., & Howard, D. L. (2012). Fate of Intravenously Administered Gold Nanoparticles in Hair Follicles: Follicular Delivery, Pharmacokinetic Interpretation, and Excretion. Advanced Healthcare Materials, 1(6), 736-741.
DOI Scopus19 WoS18 Europe PMC7
2012 Tung, H. T., Chen, I. G., Kempson, I. M., Song, J. M., Liu, Y. F., Chen, P. W., . . . Hwu, Y. (2012). Shape-controlled synthesis of silver nanocrystals by X-ray irradiation for inkjet printing. ACS Applied Materials and Interfaces, 4(11), 5930-5935.
DOI Scopus17 WoS15 Europe PMC6
2012 Zeng, Y. F., Tseng, S. J., Kempson, I. M., Peng, S. F., Wu, W. T., & Liu, J. R. (2012). Controlled delivery of recombinant adeno-associated virus serotype 2 using pH-sensitive poly(ethylene glycol)-poly-l-histidine hydrogels. Biomaterials, 33(36), 9239-9245.
DOI Scopus43 WoS38 Europe PMC25
2012 Kempson, I. M. (2012). Strands of useful information. Chemistry and industry, 76(2), 42-45.
DOI
2012 Smith, E., Gancarz, D., Rofe, A., Kempson, I. M., Weber, J., & Juhasz, A. L. (2012). Antagonistic effects of cadmium on lead accumulation in pregnant and non-pregnant mice. Journal of Hazardous Materials, 199-200, 453-456.
DOI Scopus34 WoS28 Europe PMC22
2012 Kempson, I. M., & Skinner, W. M. (2012). A comparison of washing methods for hair mineral analysis: Internal versus external effects. Biological Trace Element Research, 150(1-3), 10-14.
DOI Scopus26 WoS26 Europe PMC15
2011 Smith, E., Kempson, I. M., Juhasz, A. L., Weber, J., Rofe, A., Gancarz, D., . . . Gräfe, M. (2011). In vivo-in vitro and XANES spectroscopy assessments of lead bioavailability in contaminated periurban soils. Environmental Science and Technology, 45(14), 6145-6152.
DOI Scopus118 WoS108 Europe PMC73
2011 Barnes, T. J., Kempson, I. M., & Prestidge, C. A. (2011). Surface analysis for compositional, chemical and structural imaging in pharmaceutics with mass spectrometry: A ToF-SIMS perspective. International Journal of Pharmaceutics, 417(1-2), 61-69.
DOI Scopus49 WoS49 Europe PMC19
2011 Chen, Y. T., Chen, T. Y., Yi, J., Chu, Y. S., Lee, W. K., Wang, C. L., . . . Margaritondo, G. (2011). Hard x-ray Zernike microscopy reaches 30 nm resolution. Optics letters, 36(7), 1269-1271.
DOI Scopus53 WoS51 Europe PMC23
2011 Chen, T. Y., Chen, Y. T. T., Wang, C. L., Kempson, I. M., Lee, W. K., Chu, Y. S., . . . Margaritondo, G. (2011). Full-field microimaging with 8 keV X-rays achieves a spatial resolutions better than 20 nm. Optics express, 19(21), 19919-19924.
DOI Scopus79 WoS70 Europe PMC33
2011 Wang, C. H., Liu, C. J., Chien, C. C., Chen, H. T., Hua, T. E., Leng, W. H., . . . Margaritondo, G. (2011). X-ray synthesized PEGylated (polyethylene glycol coated) gold nanoparticles in mice strongly accumulate in tumors. Materials Chemistry and Physics, 126(1-2), 352-356.
DOI Scopus32 WoS28
2011 Wang, C. L., Hsao, B. J., Lai, S. F., Chen, W. C., Chen, H. H., Chen, Y. Y., . . . Margaritondo, G. (2011). One-pot synthesis of AuPt alloyed nanoparticles by intense x-ray irradiation. Nanotechnology, 22(6), 6 pages.
DOI Scopus29 WoS22 Europe PMC11
2011 Lai, S. F., Chen, W. C., Wang, C. L., Chen, H. H., Chen, S. T., Chien, C. C., . . . Margaritondo, G. (2011). One-pot tuning of Au nucleation and growth: From nanoclusters to nanoparticles. Langmuir, 27(13), 8424-8429.
DOI Scopus17 WoS16 Europe PMC9
2011 Tung, H. T., Hwu, Y., Chen, I. G., Tsai, M. G., Song, J. M., Kempson, I. M., & Margaritondo, G. (2011). Fabrication of single crystal CuGaS2 nanorods by X-ray irradiation. Chemical Communications, 47(32), 9152-9154.
DOI Scopus26 WoS27 Europe PMC6
2011 Lombi, E., Scheckel, K. G., & Kempson, I. M. (2011). In situ analysis of metal(loid)s in plants: State of the art and artefacts. Environmental and Experimental Botany, 72(1), 3-17.
DOI Scopus143 WoS131
2011 Cai, X., Chen, H. H., Wang, C. L., Chen, S. T., Lai, S. F., Chien, C. C., . . . Margaritondo, G. (2011). Imaging the cellular uptake of tiopronin-modified gold nanoparticles. Analytical and Bioanalytical Chemistry, 401(3), 809-816.
DOI Scopus28 WoS24 Europe PMC17
2011 Kempson, I. M., & Lombi, E. (2011). Hair analysis as a biomonitor for toxicology, disease and health status. Chemical Society Reviews, 40(7), 3915-3940.
DOI Scopus164 WoS151 Europe PMC86
2011 Chen, H. H., Chien, C. C., Petibois, C., Wang, C. L., Chu, Y. S., Lai, S. F., . . . Margaritondo, G. (2011). Quantitative analysis of nanoparticle internalization in mammalian cells by high resolution X-ray microscopy. Journal of Nanobiotechnology, 9(14), 15 pages.
DOI Scopus65 WoS59 Europe PMC41
2010 Cai, X., Wang, C. L., Chen, H. H., Chien, C. C., Lai, S. F., Chen, Y. Y., . . . Margaritondo, G. (2010). Tailored Au nanorods: Optimizing functionality, controlling the aspect ratio and increasing biocompatibility. Nanotechnology, 21(33), 8 pages.
DOI Scopus26 WoS26 Europe PMC9
2010 Kempson, I. M., & Henry, D. A. (2010). Determination of arsenic poisoning and metabolism in hair by synchrotron radiation: The case of phar lap. Angewandte Chemie International Edition, 49(25), 4237-4240.
DOI Scopus28 WoS25 Europe PMC12
2010 Denman, J. A., Skinner, W. M., Kirkbride, K. P., & Kempson, I. M. (2010). Organic and inorganic discrimination of ballpoint pen inks by ToF-SIMS and multivariate statistics. Applied Surface Science, 256(7), 2155-2163.
DOI Scopus74 WoS68
2010 Liu, C. J., Wang, C. H., Chen, S. T., Chen, H. H., Leng, W. H., Chien, C. C., . . . Margaritondo, G. (2010). Enhancement of cell radiation sensitivity by pegylated gold nanoparticles. Physics in Medicine and Biology, 55(4), 931-945.
DOI Scopus220 WoS205 Europe PMC133
2010 Kempson, I. M., Skinner, W. M., & Martin, R. R. (2010). Changes in the metal content of human hair during diagenesis from 500 years, exposure to glacial and aqueous environments. Archaeometry, 52(3), 450-466.
DOI Scopus20 WoS19
2010 Kempson, I. M., & Henry, D. (2010). Determination of arsenic poisoning and metabolism in hair by synchrotron radiation : the case of Phar Lap. Angewandte Chemie, 122(25), 4333-4336.
DOI
2010 Kempson, I. M., Martin, A. L., Denman, J. A., French, P. W., Prestidge, C. A., & Barnes, T. J. (2010). Detecting the presence of denatured human serum albumin in an adsorbed protein monolayer using TOF-SIMS. Langmuir, 26(14), 12075-12080.
DOI Scopus33 WoS33 Europe PMC23
2010 Jani, A., Kempson, I., Losic, D., & Voelcker, N. (2010). Dressing in layers: Layering surface functionalities in nanoporous aluminum oxide membranes. Angewandte Chemie-International Edition, 49(43), 7933-7937.
DOI Scopus75 WoS71 Europe PMC42
2010 Kempson, I. M., Barnes, T. J., & Prestidge, C. A. (2010). Use of TOF-SIMS to Study Adsorption and Loading Behavior of Methylene Blue and Papain in a Nano-Porous Silicon Layer. Journal of the American Society for Mass Spectrometry, 21(2), 254-260.
DOI Scopus28 WoS23 Europe PMC10
2009 Kempson, I. M., Henry, D., & Francis, J. (2009). Characterizing arsenic in preserved hair for assessing exposure potential and discriminating poisoning. Journal of Synchrotron Radiation, 16(3), 422-427.
DOI Scopus20 WoS20 Europe PMC10
2009 Smith, E., Kempson, I., Juhasz, A. L., Weber, J., Skinner, W. M., & Gräfe, M. (2009). Localization and speciation of arsenic and trace elements in rice tissues. Chemosphere, 76(4), 529-535.
DOI Scopus65 WoS59 Europe PMC35
2009 Beattie, D. A., Kempson, I. M., Fan, L. J., & Skinner, W. M. (2009). Synchrotron XPS studies of collector adsorption and co-adsorption on gold and gold: silver alloy surfaces. International Journal of Mineral Processing, 92(3-4), 162-168.
DOI Scopus32 WoS30
2008 Denman, J. A., Kempson, I. M., Skinner, W. M., & Kirkbride, K. P. (2008). Discrimination of pencil markings on paper using elemental analysis: An initial investigation. Forensic Science International, 175(2-3), 123-129.
DOI Scopus45 WoS40 Europe PMC14
2008 Prestidge, C. A., Barnes, T. J., MierczynsKa-Vasilev, A., Kempson, I., Peddie, F., & Barnett, C. (2008). Peptide and protein loading into porous silicon wafers. Physica Status Solidi A Applications and Materials Science, 205(2), 311-315.
DOI Scopus42 WoS39
2007 Kempson, I. M., Skinner, W. M., & Kirkbride, K. P. (2007). The occurrence and incorporation of copper and zinc in hair and their potential role as bioindicators: A review. Journal of Toxicology and Environmental Health Part B Critical Reviews, 10(8), 611-622.
DOI Scopus48 WoS35 Europe PMC20
2006 Kempson, I. M., Skinner, W. M., & Kirkbride, K. P. (2006). Advanced analysis of metal distributions in human hair. Environmental Science and Technology, 40(10), 3423-3428.
DOI Scopus60 WoS55 Europe PMC22
2005 Kempson, I. M., Kirkbride, K. P., Skinner, W. M., & Coumbaros, J. (2005). Applications of synchrotron radiation in forensic trace evidence analysis. Talanta, 67(2), 286-303.
DOI Scopus34 WoS26 Europe PMC13
2005 Kempson, I. M., & Skinner, W. M. (2005). ToF-SIMS analysis of elemental distributions in human hair. Science of the Total Environment, 338(3), 213-227.
DOI Scopus65 WoS62 Europe PMC32
2005 Martin, R. R., Kempson, I. M., Naftel, S. J., & Skinner, W. M. (2005). Preliminary synchrotron analysis of lead in hair from a lead smelter worker. Chemosphere, 58(10), 1385-1390.
DOI Scopus51 WoS45 Europe PMC28
2003 Kempson, I. M., Skinner, W. M., & Kirkbride, P. K. (2003). Calcium distributions in human hair by ToF-SIMS. Biochimica Et Biophysica Acta General Subjects, 1624(1-3), 1-5.
DOI Scopus36 WoS32 Europe PMC12
2003 Kempson, I. M., Skinner, W. M., Kirkbride, P. K., Nelson, A. J., & Martin, R. R. (2003). Time-of-flight secondary ion mass spectrometry analysis of hair from archaeological remains. European Journal of Mass Spectrometry, 9(6), 589-597.
DOI Scopus31 WoS31 Europe PMC14
2003 Kempson, I. M., Skinner, W. M., Kirkbride, K., Nelson, A., & Martin, R. (2003). Mass spectroscopic analysis of hair from archaelogical remains. Microscopy and microanalysis, 9(SUPPL. 2), 650-651.
DOI
2003 Kempson, I. M., Skinner, W. M., & Kirkbride, K. (2003). Investigations into hair analysis by ToF-SIMS. Microscopy and microanalysis, 9(SUPPL. 2), 1216-1217.
DOI
2002 Kempson, I. M., Skinner, W. M., & Kirkbride, K. P. (2002). A method for the longitudinal sectioning of single hair samples. Journal of Forensic Sciences, 47(4), 889-892.
DOI Scopus26 WoS22 Europe PMC9

Year Citation
2019 Kempson, I., & Turnbull, T. (2019). WO2019079841A1, Nanoparticle cancer therapy.

Year Citation
2025 Atkinson, J., Chopin, J., Bezak, E., Le, H., & Kempson, I. (2025). Mechanisms of ATM Inhibitor AZD1390-Mediated Radiosensitization by Comparing DNA DSB Formation and Repair in 4T1 Cells.
DOI
2024 Yang, C. -T., Cho, I. -C., Yu, C. -F., Cheah, E., Liu, T., Lin, Y. -P., . . . Thierry, B. (2024). 3D printed microtissue cassettes enabling high throughput proton radiobiological assays.
DOI

  • DNA damage assessment for preclinical screening of therapeutic strategies, Mark Hughes Foundation Limited, 06/03/2025 - 31/12/2026

  • Therapeutic and Bio-Equivalence Comparison of Isomers, Rize Oncology Australia Pty Ltd, 31/07/2025 - 31/10/2026

  • Nanoparticle regulation of DNA replication and repair pathways, ARC - Discovery Projects, 21/01/2019 - 29/06/2023

  • Priming cancer for radiotherapy, Tour de Cure Ltd, 01/01/2020 - 30/09/2022

Courses I teach

  • NASC 3015 Atomic, Nuclear, and Radiation Science (2025)
  • NASC 1011 Honours Research Project 2 N (2024)
  • NASC 3015 Atomic, Nuclear, and Radiation Science (2024)
  • NASC 4021 Scientific Practice (2024)
  • PHYS 2004 Applied Physics 4 (2024)

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Geofrey John
2025 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mr Luke Samuel Roeger
2023 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Jalil Charmi
2022 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mr Quang Minh Luu
2019 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mr QUY VAN CHANH LE

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