Mr Jalil Charmi
Higher Degree by Research Candidate
School of Medicine
College of Health
PhD Researcher | Nanomedicine & Biomaterials | TEM operator | Educator
I am a PhD Researcher and Educator with over a decade of expertise spanning nanophysics, biomedical engineering, and advanced material synthesis. Currently completing my doctoral research at Adelaide University, my work focuses on developing multifunctional "theranostic" agents designed for simultaneous cancer imaging and the enhancement of radiotherapy efficacy.
In My PhD, I am investigating a novel nanotechnology-based radiosensitisation strategy to improve cancer treatment outcomes. Specifically, I am utilizing FerroTrace® Superparamagnetic Iron Oxide Nanoparticles (IONPs), stabilized with polyacrylamide copolymers and conjugated with Fibroblast Activation Protein (FAP) ligands developed in collaboration with Purdue University. My research evaluates how these targeted nanoparticles enhance the efficacy of X-ray radiation against cancer-associated fibroblasts. By employing a rigorous multiparametric approach—including clonogenic survival assays, ROS assay—I aim to validate increased cellular death and precise tumor mapping through the MRI and MPI. Supported by Ferronova, this project bridges the gap between complex nanotechnology and clinical application, positioning my findings within a real-world translational pipeline for more precise cancer therapy.
Throughout my career, I have specialized in the design and modification of nanoparticles for oncology, with a particular emphasis on:
Nanomaterial Synthesis: Expert in the green synthesis of bismuth, gold, silver, and platinum-based nanoparticles for radiosensitization.
Advanced Characterization: Proficient in high-level laboratory techniques, including TEM facility management, SEM, XPS, and magnetic characterization (VSM).
Preclinical Research: Extensive experience in cell culture (MTT assays, ROS generation) and in vivo animal studies to evaluate drug delivery systems and CRISPR/Cas9 delivery.
Beyond the lab, I am a dedicated educator with a strong background in teaching Physics and Specialist Mathematics. I take pride in mentoring the next generation of scientists, helping students transform their academic performance through critical thinking and rigorous problem-solving strategies.
Core Expertise:
Scientific: Nanomedicine, Radiosensitization, Drug Delivery Systems, MRI/CT Contrast Agents, and 3D Bioprinting.
Technical: Spectroscopy (ICP-MS, FTIR, EPR), Thermal Analysis (TGA/DSC), and Data Analysis (MATLAB, Origin Pro, GraphPad Prism).
Languages: English, Persian, and Turkish.
I am always open to collaborating with fellow researchers, clinicians, and industry professionals at the intersection of nanotechnology and healthcare.
Jalil Charmi is a researcher specializing in Nanobiotechnology and Medical Physics, currently contributing to the advancement of precision medicine through his work with Ferronova and the Adelaide University . His research focuses on the development of sophisticated theranostic nanoplatforms and radiosensitizers that improve the detection and treatment of complex cancers. By engineering "smart" nanoparticles—such as Iron oxide, gold, bismuth, and bimetallic hybrids—Jalil seeks to enhance the efficacy of radiotherapy and targeted drug delivery. His collaboration with Ferronova underscores a commitment to bridging the gap between benchtop innovation and clinical oncology, specifically in the realm of image-guided surgery and targeted therapeutics.
Academic Affiliations:
Jalil has been associated with several international research institutions, including:
Adelaide University (Future Industries Institute), Australia (April 2023 to Now)
Erciyes University (Nanotechnology Research and Application Center - ERNAM), Turkey (Jan 2021 to Feb 2023)
Zanjan Pharmaceutical Nanotechnology Research Center (ZPNRC), School of Pharmacy at Zanjan University of Medical Sciences (ZUMS) in Zanjan, Iran (Oct 2017 to Jul 2020)
University of Zanjan (Department of Physics), Iran (Sep 2016 to Feb 2018)
Recent News about Jalil following through LinkedIn
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2023 | Scholarship | Australian Government Research Training Program International (RTPi) Scholarship | Adelaide University | Australia | AUD $39,700 |
| 2021 | Scholarship | Scientific and Technological Research Council of Turkey (TUBITAK) | Erciyes University | Turkey | - |
| Year | Citation |
|---|---|
| 2024 | Nomani, A., Nosrati, H., Faraji, N., Charmi, J., & Javani, S. (2024). Bismuth-gold nanohybrid based nano photosensitizer to combat antimicrobial resistance. Scientific Reports, 14(1), 22598. Scopus3 Europe PMC2 |
| 2023 | Ghaffarlou, M., Mohammadi, A., Mousazadeh, N., Salehiabar, M., Kalantari, Y., Charmi, J., . . . Javani, S. (2023). Facile preparation of silver based radiosensitizers via biomineralization method for enhanced in vivo breast cancer radiotherapy. Scientific Reports, 13(1), 15131. Scopus13 Europe PMC7 |
| 2023 | Nosrati, H., Salehiabar, M., Charmi, J., Yaray, K., Ghaffarlou, M., Balcioglu, E., & Ertas, Y. N. (2023). Enhanced In Vivo Radiotherapy of Breast Cancer Using Gadolinium Oxide and Gold Hybrid Nanoparticles. ACS Applied Bio Materials, 6(2), 784-792. Scopus56 Europe PMC39 |
| 2023 | Charmi, J., Seidi, F., Amereh, M., Ghaffarlou, M., Salehiabar, M., Yousefnejad, S., . . . Nosrati, H. (2023). Synthesis of Pt nanoparticles with gelatin-assisted green route to improve sensitization of cancer cells to X-Ray irradiation. International Journal of Pharmaceutics, 643, 123148. Scopus8 Europe PMC1 |
| 2023 | Rashidzadeh, H., Seidi, F., Ghaffarlou, M., Salehiabar, M., Charmi, J., Yaray, K., . . . Ertas, Y. N. (2023). Preparation of alginate coated Pt nanoparticle for radiosensitization of breast cancer tumor. International Journal of Biological Macromolecules, 233, 123273. Scopus32 Europe PMC22 |
| 2022 | Walweel, N., Kutlu, A. U., Yilmaz, U., Al-Shaebi, Z., Charmi, J., & Aydin, O. (2022). Review: mRNA delivery systems in vaccinations and COVID-19. Journal of Research in Pharmacy, 26(5), 1084-1101. |
| 2022 | Nosrati, H., Salehiabar, M., Mozafari, F., Charmi, J., Erdoğan, N., Ghaffarlou, M., . . . Nuri Ertas, Y. (2022). Preparation and evaluation of bismuth sulfide and magnetite-based theranostic nanohybrid as drug carrier and dual MRI/CT contrast agent. Applied Organometallic Chemistry, 36(11), 10 pages. Scopus29 WoS28 |
| 2020 | Rahimi, H., Salehiabar, M., Charmi, J., Barsbay, M., Ghaffarlou, M., Roohi Razlighi, M., . . . Webster, T. J. (2020). Harnessing nanoparticles for the efficient delivery of the CRISPR/Cas9 system. Nano Today, 34, 28 pages. Scopus75 WoS64 |
| 2020 | Faghfoori, M. H., Nosrati, H., Rezaeejam, H., Charmi, J., Kaboli, S., Johari, B., & Danafar, H. (2020). Anticancer effect of X-Ray triggered methotrexate conjugated albumin coated bismuth sulfide nanoparticles on SW480 colon cancer cell line. International Journal of Pharmaceutics, 582, 9 pages. Scopus43 WoS44 Europe PMC22 |
| 2020 | Abhari, F., Charmi, J., Rezaeejam, H., Karimimoghaddam, Z., Nosrati, H., Danafar, H., & Farajollahi, A. (2020). Folic Acid Modified Bismuth Sulfide and Gold Heterodimers for Enhancing Radiosensitization of Mice Tumors to X-ray Radiation. ACS Sustainable Chemistry and Engineering, 8(13), 5260-5269. Scopus49 WoS47 |
| 2020 | Nosrati, H., Charmi, J., Abhari, F., Attari, E., Bochani, S., Johari, B., . . . Danafar, H. (2020). Improved synergic therapeutic effects of chemoradiation therapy with the aid of a co-drug-loaded nano-radiosensitizer under conventional-dose X-ray irradiation. Biomaterials Science, 8(15), 4275-4286. Scopus27 WoS26 Europe PMC13 |
| 2019 | Nosrati, H., Tarantash, M., Bochani, S., Charmi, J., Bagheri, Z., Fridoni, M., . . . Kheiri Manjili, H. (2019). Glutathione (GSH) Peptide Conjugated Magnetic Nanoparticles As Blood-Brain Barrier Shuttle for MRI-Monitored Brain Delivery of Paclitaxel. ACS Biomaterials Science and Engineering, 5(4), 1677-1685. Scopus63 WoS58 |
| 2019 | Nosrati, H., Abhari, F., Charmi, J., Davaran, S., & Danafar, H. (2019). Multifunctional nanoparticles from albumin for stimuli-responsive efficient dual drug delivery. Bioorganic Chemistry, 88, 7 pages. Scopus25 WoS23 Europe PMC17 |
| 2019 | Nosrati, H., Abhari, F., Charmi, J., Rahmati, M., Johari, B., Azizi, S., . . . Danafar, H. (2019). Facile green synthesis of bismuth sulfide radiosensitizer via biomineralization of albumin natural molecule for chemoradiation therapy aim. Artificial Cells Nanomedicine and Biotechnology, 47(1), 3832-3838. Scopus18 WoS14 Europe PMC5 |
| 2019 | Nosrati, H., Charmi, J., Salehiabar, M., Abhari, F., & Danafar, H. (2019). Tumor Targeted Albumin Coated Bismuth Sulfide Nanoparticles (Bi2S3) as Radiosensitizers and Carriers of Curcumin for Enhanced Chemoradiation Therapy. ACS Biomaterials Science and Engineering, 5(9), 4416-4424. Scopus60 WoS57 Europe PMC29 |
| 2019 | Charmi, J., Nosrati, H., Mostafavi Amjad, J., Mohammadkhani, R., & Danafar, H. (2019). Polyethylene glycol (PEG) decorated graphene oxide nanosheets for controlled release curcumin delivery. Heliyon, 5(4), 14 pages. Scopus102 WoS94 Europe PMC48 |
| 2018 | Nosrati, H., Charmi, J., Abedini, S., Rashidi, N., Attari, E., Davaran, S., . . . Kheiri Manjili, H. (2018). Preparation and characterization of magnetic theranostic nanoparticles for curcumin delivery and evaluation as MRI contrast agent. Applied Organometallic Chemistry, 32(12), 9 pages. Scopus11 WoS7 |
| 2018 | Nosrati, H., Abbasi, R., Charmi, J., Rakhshbahar, A., Aliakbarzadeh, F., Danafar, H., & Davaran, S. (2018). Folic acid conjugated bovine serum albumin: An efficient smart and tumor targeted biomacromolecule for inhibition folate receptor positive cancer cells. International Journal of Biological Macromolecules, 117, 1125-1132. Scopus112 WoS102 Europe PMC60 |
Training – I am undertaking a 3.5-year full-time PhD titled “Development of a Theranostic Agent for Image-Guided and Radiosensitisation of Pancreatic Cancer”, supported by the highly competitive Australian Government Research Training Program International (RTPi) Scholarship. This scholarship covers full tuition and provides an annual stipend of AUD $39,700.
Jalil's research focuses on designing multifunctional nanoparticles for simultaneous cancer imaging and enhancing radiotherapy efficacy, involving synthesis, characterization, and preclinical evaluation. [2023], Performance award 12000 TL from 2250-Lisansüstü Burslari Performans Programi 2022/1, Project No: 118C346, TUBITAK BIDEB,
Project Title: Production of Highly Magnetic Nanoparticles using Nanofabrication Approaches and Their Applications as MRI Contrast Agents [2022], Scholarship of 2,920,000 TL from The Scientific and Technological Research Council of Turkey (TUBITAK-2232)
Project Title: Production of Highly Magnetic Nanoparticles using Nanofabrication Approaches and Their Applications as MRI Contrast Agents [2021], Scholarship of 650.000 TL from Büyük Ögrenci Projesi (BOP) at T.C. Erciyes Üniversitesi Bilimsel Arastirma Projeleri Koordinasyon Birimi, Turkey
Project Title: Aptamer-functionalized smart materials for targeted quantification of some of cancer biomarker using Electrochemical (EC) techniques [2021], Research Grant of 300.000.000 IRR from Golestan University of Medical Sciences in Gorgan, Iran
Project Title: Designing and developing photodynamic therapy green LED set-up (540 nm and 2.5 mV) for evaluation antibacterial properties of bismuth gold nano-hybrid conjugated to HEX-linked oligonucleotide as optical nanosensor (tracing code 111679) [2018]
Math and physic teacher | Senior Physics & Math Tutor (Sep 2025 to Present)
Private Tutoring (Self-Employed) | Physics & Math Educator
Face-to-Face | Adelaide, SA |
- Personalized Learning Design: Founded a private tutoring practice providing bespoke, one-on-one education tailored to the unique learning styles of diverse students (Year 7–12).
- In-Depth Problem Solving: Guided students through rigorous mathematical derivations and physics problem-solving strategies, fostering critical thinking and independent study habits.
- Flexible Delivery: Managed all scheduling, curriculum sourcing, and client relations, maintaining a consistent roster of long-term students through high referral rates and proven grade improvements.
Grade Transformation: Successfully mentored students, consistently elevating academic performance from average grades (C/B) to Distinction and High Distinction (A/A+) levels in Physics and Specialist Mathematics.
Mathematics and English Language teaching (Part-time) Tutor | RASA Institute (Jun 2016 to Mar 2020)
Class-group oriented | Iran, Zanjan|
- Preparation of the course materials and Teaching practices
- Examination of the students
| Date | Event Name | Event Type | Institution | Country |
|---|---|---|---|---|
| 2025 - 2025 | 10th Annual Symposium of the Australian Society of Molecular Imaging | Symposium | Australian Society of Molecular Imaging | Australia |
| 2025 - 2025 | IUPESM World Congress 2025 | Conference | International | Australia |
| Date | Engagement Type | Partner Name |
|---|---|---|
| 2025 - ongoing | Collaboration | Ferronova |
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