Gregory Goodall

Gregory Goodall

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Professor Greg Goodall
Head, Gene Regulation Section
Qualifications: B.Sc. (Adelaide), PhD (Adelaide).

Prof Gregory Goodall is head of the Gene Regulation Laboratory at the Centre for Cancer Biology, Adelaide. His research revolves around the roles that microRNAs play in cancer metastasis. His group was among the first to construct and use microRNA microarrays, which in collaboration with the EMT group of Prof. Yeesim Khew-Goodall lead to the landmark discovery of a microRNA family that controls EMT, with important implications for tumour metastasis. Their report in Nature Cell Biol (2008) is the most highly cited of all papers on microRNAs in cancer. Prof Goodall has been a Postdoctoral Fellow of the Roche Institute of Molecular Biology, NJ, Research Fellow at Cornell University Medical School, NY and at the Friedrich Miescher Institute, Basel, Switzerland. He currently heads the Gene Regulation Section at the Centre for Cancer Biology and is co-Director of the CCB ACRF Cancer Genomics Facility. He is a fellow of the Australian Academy of Science and of the Australian Academy of Health and Medical Sciences. He serves on the editorial board of the journal Oncogene.

https://www.centreforcancerbiology.org.au/research/laboratories/gene-regulation-section/

Key Achievements and Awards
• Discovered further links between miR-200, ZEB transcription repressors and TGF-β in control of EMT.
• Used mouse cancer models to determine effects of miR-200 on cancer metastasis.
• Has developed genome wide methods for identifying microRNAs and circular RNAs in cancer cells.
• Fellow of the Australian Academy of Science
• Fellow of the Australian Academy of Health and Medical Sciences.
• Awarded Lorne Genome Conference Julian Wells Medal

  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2023 Co-Supervisor Immunological determinants of head and neck cancer progression and metastasis, in particular the role of cancer associated fibroblasts Master of Philosophy (Surgery) Master Full Time Miss Laura Kenyon
    2021 Co-Supervisor Understanding how the Epigenetic Field Effect Exerted by Cancers upon their Microenvironment Promotes Tumour Progression Doctor of Philosophy Doctorate Full Time Miss Moganalaxmi Reckdharajkumar
    2020 Co-Supervisor Transforming growth factor beta as a differential regulator of Beta common receptor and Interleukin 3 receptor alpha expression. Doctor of Philosophy Doctorate Full Time Mrs Sepideh Azizi Taramsary
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2012 - 2017 Principal Supervisor A Role for Bivalent Genes in Epithelial to Mesenchymal Transition Doctor of Philosophy Doctorate Part Time Mr Francisco Sadras
    2012 - 2024 Principal Supervisor Regulation of Breast Cancer Progression and Metastasis by MicroRNA-342-3p Doctor of Philosophy Doctorate Part Time Dr Victoria Kiriaki Arnet
    2010 - 2012 Principal Supervisor The miR 200 Family is Controlled by Epigenetic based Mechanisms and Mediates Transition Between Non Stem and Stem like Cell Phenotypes Doctor of Philosophy Doctorate Full Time Mr Yat Yuen Lim
    2010 - 2015 Principal Supervisor Insight into the function of microRNAs and other small RNAs of diverse origin Doctor of Philosophy Doctorate Full Time Mr Daniel Wyville Thomson
    2008 - 2013 Principal Supervisor Regulation of the microRNA-200 family during epithelial to mesenchymal transition Doctor of Philosophy Doctorate Full Time Miss Natasha Kolesnikoff
    2006 - 2010 Co-Supervisor Regulation of Sphingosine Kinase 1 Signalling by Calcium- and Integrin-binding Proteins Doctor of Philosophy Doctorate Full Time Ms Kate Jarman
    2006 - 2010 Principal Supervisor Downregulation of the MicroRNA-200 Family Induces Epithelial to Mesenchymal Transition Doctor of Philosophy Doctorate Full Time Miss Emily Paterson
    2006 - 2012 Co-Supervisor Gene Regulation by Sphingosine Kinase Doctor of Philosophy Doctorate Full Time Dr Duyen Pham
    1999 - 2003 Co-Supervisor Hypoxia-Inducable Factor-1(alpha) mRNA Contains An Internal Ribosome Entry Site That Allows Efficient Translation During Normoxia And Hypoxia Doctor of Philosophy Doctorate Full Time Dr Kenneth Lang

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