Natasha Prizzi

Dr Natasha Prizzi

Research Associate

Centre for Cancer Biology

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.


I am a post-doctoral researcher at the Centre for Cancer Biology (an alliance of the University of South Australia and SA Pathology) in Adelaide in the Tumour Microenvironment laboratory with A/Prof Michael Samuel. My current research focuses include skin cancer and cutaneous wound healing. In particular I am interested in identifying the role of mast cells in the tumour microenvironment and their contribution to the initiation of skin carcinogenesis.
My PhD investigated the transcriptional regulation of a family of microRNA genes during epithelial to mesencymal transition with Prof Gregory Goodall and Dr Philip Gregory. I have also worked with Michele Grimbaldeston to investigate the effect of vitamin D on restraining mast cell function in IgE-dependent activation.

Year Citation
2024 Johan, M. Z., Pyne, N. T., Kolesnikoff, N., Poltavets, V., Esmaeili, Z., Woodcock, J. M., . . . Samuel, M. S. (2024). Accelerated Closure of Diabetic Wounds by Efficient Recruitment of Fibroblasts upon Inhibiting a 14-3-3/ROCK Regulatory Axis. The Journal of Investigative Dermatology, 144(11), 2562-2573.e4.
DOI Scopus1 WoS1 Europe PMC1
2022 Kolesnikoff, N., Chen, C. -H., & Samuel, M. S. (2022). Interrelationships between the extracellular matrix and the immune microenvironment that govern epithelial tumour progression. Clinical Science, 136(5), 361-377.
DOI Scopus35 WoS34 Europe PMC36
2020 Boyle, S. T., Poltavets, V., Kular, J., Pyne, N. T., Sandow, J. J., Lewis, A. C., . . . Samuel, M. S. (2020). ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism. Nature Cell Biology, 22(7), 882-895.
DOI Scopus60 WoS60 Europe PMC57
2020 Boyle, S. T., Poltavets, V., Kular, J., Pyne, N. T., Sandow, J. J., Lewis, A. C., . . . Samuel, M. S. (2020). Publisher Correction: ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism.. Nat Cell Biol, 22(7), 908.
DOI Scopus5 WoS4 Europe PMC6
2016 Yip, K., Kolesnikoff, N., Hauschild, N., Biggs, L., Lopez, A., Galli, S., . . . Grimbaldeston, M. (2016). The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation. Nature Communications, 7(article no. 13198), 13198-1-13198-14.
DOI Scopus31 WoS30 Europe PMC25
2015 Tong, P., Roediger, B., Kolesnikoff, N., Biro, M., Tay, S., Jain, R., . . . Weninger, W. (2015). The skin immune atlas: three-dimensional analysis of cutaneous leukocyte subsets by multiphoton microscopy. Journal of Investigative Dermatology, 135(1), 84-93.
DOI Scopus101 WoS92 Europe PMC81
2015 Kular, J., Scheer, K., Pyne, N., Allam, A., Pollard, A., Magenau, A., . . . Samuel, M. (2015). A negative regulatory mechanism involving 14-3-3ζ limits signaling downstream of ROCK to regulate tissue stiffness in epidermal homeostasis. Developmental Cell, 35(6), 759-774.
DOI Scopus30 WoS24 Europe PMC29
2014 Kolesnikoff, N., Attema, J., Roslan, S., Bert, A., Schwarz, Q., Gregory, P., & Goodall, G. (2014). Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition. Journal of Biological Chemistry, 289(16), 11194-11205.
DOI Scopus61 WoS57 Europe PMC53
2014 Yip, K., Kolesnikoff, N., Yu, C., Hauschild, N., Taing, H., Biggs, L., . . . Grimbaldeston, M. (2014). Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation. Journal of Allergy and Clinical Immunology, 133(5), 1356-1379.
DOI Scopus102 WoS89 Europe PMC78
2013 Attema, J., Bert, A., Lim, Y., Kolesnikoff, N., Lawrence, D., Pillman, K., . . . Goodall, G. (2013). Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells. PLoS One, 8(9), 1-15.
DOI Scopus21 WoS19 Europe PMC19
2008 Paterson, E., Kolesnikoff, N., Gregory, P., Bert, A., Khew-Goodall, Y., & Goodall, G. (2008). The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition. The Scientific World Journal, 8, 901-904.
DOI Scopus76 WoS72 Europe PMC61
2008 Bracken, C., Gregory, P., Kolesnikoff, N., Bert, A., Wang, J., Shannon, M., & Goodall, G. (2008). A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Research, 68(19), 7846-7854.
DOI Scopus959 WoS908 Europe PMC856
  • How can we predict bowel cancer recurrence?, Cancer Council SA - Beat Cancer, 01/01/2023 - 31/12/2023

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor Understanding how the epigenetic field effect exerted by cancers upon their microenvironment promotes tumour progression Doctor of Philosophy Doctorate Full Time Mrs Zahra Esmaeili

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