Darryl Russell

Research Interests

Cancer Biology and Clinical Oncology Early Origins of Health Fertility and Conception Biochemistry and Cell Biology Bioinformatics Biotechnology Cancer Cell Biology Cell Biology Fertility Reproductive Biology

Prof Darryl Russell

Professorial Research Fellow (E)

School of Biomedicine

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

1. Revealing the molecular mechanism of controlled tissue morphogenesis in ovaries, and understand how the changing ovarian environment promotes oocyte quality leading to diagnostic and therapeutic means to enhance the health of women and their babies in natural fertility and Assisted Reproductive Technology settings2. Generating a full understanding of the mechanism of ovulation of matured oocytes and discover molecular targets and new drugs that block ovulation leading to improved, safer and acute acting contraceptives.3. Understanding development and progression of cancers of reproductive organs

My research group focuses broadly on intercellular communication, cell-matrix interactions and resulting cell signalling and morphogenesis both in normal function and cancer of the reproductive organs.

Our primary focus is on the cyclic remodelling of the ovary during folliculogenesis, atresia, ovulation and luteinisation. Together these processes determine reproductive success and the health the oocyte and hence a healthy start to life.

Australia has one of the highest rates of dependence on Assisted Reproductive Technology (ART) internationally, resulting in over 4,000 births (~3%) annually. Gamete insufficiency is the main cause of infertility and determinant of embryo health and subsequent ART success.  Infertility and polycystic ovary syndrome (PCOS) are both extremely common in the Australian population and both associate with dysregulated ovarian tissue remodelling. Infertility treatment carries serious risks for women due to hormone stimulations, surgical procedures and multiple pregnancies. All the above may be prevented through our work, by understanding the mechanisms of ovarian function and dysfunction and perfecting therapies to address these directly.

Additionally, contraception is among the most important medical drivers of health and economic development through advancing women’s health and opportunities for education and employment through family planning.  Existing contraceptive technologies are not suitable in many circumstances, meaning that nearly a quarter billion women live with unmet need for contraception.  Our research applies functional genomics and drug screening approaches to identify new molecular targets and drugs that can directly block ovulation.  The ultimate goal is to improve accessibility, convenience of use and risk of side effects so that women who need it most have access to effective family planning.

Our Aims :

1.To generate a full understanding of the mechanism of hormone action that control the unique function of the ovary and discover molecular targets and new drugs that block ovulation leading to safer contraceptives with reduced undesirable off-target effects and acute action.

2. To reveal the molecular mechanism of controlled tissue morphogenesis in ovaries, and understand how the changing ovarian environment promotes oocyte quality leading to diagnostic and therapeutic means to enhance the health of women and their babies in natural fertility and Assisted Reproductive Technology settings

Specific Research Projects are Addressing:

· Discovery of molecular targets and drug candidates for blocking ovulation leading to development of improved contraception.

· Identifying biomarkers of oocyte developmental competence

· Molecular mechanisms of ovulation

3. Understanding development and progression of cancers of reproductive organs

Extracellular matrix remodelling and tissue morphogenesis also cause metastases of reproductive organ cancers. Cancer of the breast, prostate, ovary and female reproductive tract account for more than 40% of all cancers in the Australian population (Cancer in Australia: an overview 2006. AIHW Publications 2006;37:144). One in eight Australian women will develop breast cancer and one in 9 men will develop prostate cancer. Each year 3000 women die from breast cancer, and a similar number of men die from prostate cancer, Cancer that progresses to metastatic stage in breast, ovary, prostate or reproductive tracts are often incurable and thus my work also focuses on understanding how cancers become metastatic and how this can be prevented to improve ageing productively.

Our research seeks to understand the biological basis underlying the cause and mechanism of progression to metastatic disease. The changes that arise in malignant tissue to endow their capacity to degrade local extracellular matrix barriers and invade local blood and/or lymphatic vessels for transport to distal sites is under investigation. We aim to develop tests to identify the risk of metastatic disease as well as antimetastatic therapies that specifically target the capacity of tumor cells to invade local tissues, to migrate and to populate new tissues.

Specific research projects are addressing:

· The interaction of tumor cells with local non-malignant stromal tissues

· Proteases of the Adamts family that facilitate degradation of peritumoral ECM

· Tumor mediated angiogenesis and lymphangiogenesis

Research Funding:

NHMRC Project Grants and Fellowships

Bill and Melinda Gates Foundation

ARC Discovery Grants and Fellowship

Prostate Cancer Foundation Grant

Research Interests

Biochemistry and Cell Biology.  Bioinformatics.  Biotechnology.  Cell Biology.  Fertility.  Early Origins of Health.  Fertility and Conception.  Reproductive Biology.

Cancer Cell Biology.  Clinical Oncology. 

Date Position Institution name
2017 - ongoing Professor University of Adelaide
2016 - ongoing NHMRC Senior Research Fellow The University of Adelaide
2009 - 2016 ARC Future Fellow University of Adelaide
2006 - 2009 NHMRC Career Development Fellow University of Adelaide
2003 - 2006 Georgina Dowling Research Fellow University of Adelaide

Date Institution name Country Title
1995 Monash University Australia PhD

Year Citation
2025 Moore, V., Rumbold, A., Fernandez, R., McElroy, H., Moore, L., Giles, L., . . . Davies, M. (2025). Clomiphene citrate medication for infertility and risk of stillbirth or neonatal death: a population-based cohort study. Journal of Clinical Endocrinology and Metabolism, 110(7), 1818-1827.
DOI WoS1 Europe PMC1
2025 Winstanley, Y. E., Rose, R. D., Sobinoff, A. P., Wu, L. L., Adhikari, D., Zhang, Q. -H., . . . Robker, R. L. (2025). Telomere length in offspring is determined by mitochondrial-nuclear communication at fertilization. Nature Communications, 16(1), 2527-1-2527-20.
DOI Scopus2 WoS2 Europe PMC1
2025 Allen, T. P., Roennfeldt, A. E., Reckdharajkumar, M., Sullivan, A. E., Liu, M., Quinn, R. J., . . . Bersten, D. C. (2025). dFLASH; dual FLuorescent transcription factor activity sensor for histone integrated live-cell reporting and high-content screening. Nature Communications, 16(1), 3298-1-3298-18.
DOI
2025 Foot, N. J., Dinh, D. T., Emery-Corbin, S. J., Yousef, J. M., Dagley, L. F., & Russell, D. L. (2025). Comparative Analysis of the Progesterone Receptor Interactome in the Human Ovarian Granulosa Cell Line KGN and Other Female Reproductive Cells. Proteomics, 25(13), e202400374.
DOI Scopus1 WoS1 Europe PMC1
2025 Caracuel-Peramos, R., Rodríguez-Baena, F. J., Redondo-García, S., Villatoro-García, J. A., García-Muñoz, A., Peris-Torres, C., . . . Rodríguez-Manzaneque, J. C. (2025). Loss of the extracellular protease ADAMTS1 reveals an antitumorigenic program involving the action of NIDOGEN-1 on macrophage polarization. OncoImmunology, 14(1), 11 pages.
DOI Scopus1 WoS1 Europe PMC1
2025 Zaniker-Gomez, E. J., Yan, Z., Yang, J., Russell, D. L., Zhang, H., Sun, S. X., & Duncan, F. E. (2025). Microscale pressure measurements and optical coherence tomography reveal time-dependent biomechanical stages of ovulation in mice. Iscience, 28(12), 114086.
DOI
2024 Winstanley, Y. E., Liu, J., Adhikari, D., Gonzalez, M. B., Russell, D. L., Carroll, J., & Robker, R. L. (2024). Dynamics of Mitochondrial DNA Copy Number and Membrane Potential in Mouse Pre-Implantation Embryos: Responses to Diverse Types of Oxidative Stress. Genes, 15(3), 15030367-1-15030367-18.
DOI Scopus7 WoS7 Europe PMC5
2024 Chin, P. Y., Chan, H. Y., Kieffer, T. E. C., Prins, J. R., Russell, D. L., Davies, M. J., & Robertson, S. A. (2024). Clomiphene citrate administered in peri-conception phase causes fetal loss and developmental impairment in mice. Endocrinology, 165(7), bqae047-1-bqae047-15.
DOI Scopus2 WoS1 Europe PMC2
2024 Morimoto, A., Rose, R. D., Smith, K. M., Dinh, D. T., Umehara, T., Winstanley, Y. E., . . . Robker, R. L. (2024). Granulosa cell metabolism at ovulation correlates with oocyte competence and is disrupted by obesity and aging. Human Reproduction, 39(9), 2053-2066.
DOI Scopus17 WoS15 Europe PMC14
2024 Winstanley, Y. E., Gonzalez, M. B., Andreas, E., Connaughton, H., Bergen, J., Ween, M., . . . Robker, R. L. (2024). Drinking water quality impacts oocyte viability and embryo development. Frontiers in Reproductive Health, 6, 1-14.
DOI Scopus1 WoS1
2023 Dinh, D. T., Breen, J., Nicol, B., Foot, N. J., Bersten, D. C., Emery, A., . . . Russell, D. L. (2023). Progesterone receptor mediates ovulatory transcription through RUNX transcription factor interactions and chromatin remodelling.. Nucleic Acids Research, 51(12), 5981-5996.
DOI Scopus16 WoS16 Europe PMC20
2023 Roennfeldt, A. E., Allen, T. P., Trowbridge, B. N., Beard, M. R., Whitelaw, M. L., Russell, D. L., . . . Peet, D. J. (2023). NanoFIRE: A NanoLuciferase and Fluorescent Integrated Reporter Element for Robust and Sensitive Investigation of HIF and Other Signalling Pathways. Biomolecules, 13(10), 1545-1-1545-16.
DOI
2023 Emery, A., Dunning, K. R., Dinh, D. T., Akison, L. K., Robker, R. L., & Russell, D. L. (2023). Dynamic regulation of semaphorin 7A and adhesion receptors in ovarian follicle remodeling and ovulation. Frontiers in Cell and Developmental Biology, 11, 1261038-1-1261038-9.
DOI Scopus7 WoS7 Europe PMC5
2022 Bersten, D. C., Sullivan, A. E., McDougal, D., Breen, J., Fitzsimmons, R. L., Muscat, G. E. O., . . . Whitelaw, M. L. (2022). Core and Flanking bHLH-PAS:DNA interactions mediate specificity and drive obesity.
DOI Europe PMC1
2022 Smith, K. M., Dinh, D. T., Akison, L. K., Nicholls, M., Dunning, K. R., Morimoto, A., . . . Robker, R. L. (2022). Intraovarian, Isoform-Specific Transcriptional Roles of Progesterone Receptor in Ovulation. Cells, 11(9), 1-23.
DOI Scopus11 WoS10 Europe PMC7
2022 Umehara, T., Winstanley, Y. E., Andreas, E., Morimoto, A., Williams, E. J., Smith, K. M., . . . Robker, R. L. (2022). Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary.. Science Advances, 8(24), eabn4564-1-eabn4564-17.
DOI Scopus149 WoS151 Europe PMC141
2022 Dinh, D. T., & Russell, D. L. (2022). Nuclear Receptors in Ovarian Function. Advances in experimental medicine and biology, 1390, 41-58.
DOI Scopus2 Europe PMC2
2021 Schjenken, J. E., Green, E. S., Overduin, T. S., Mah, C. Y., Russell, D. L., & Robertson, S. A. (2021). Endocrine disruptor compounds-a cause of impaired immune tolerance driving inflammatory disorders of pregnancy?. Frontiers in Endocrinology, 12, 607539-1-607539-15.
DOI Scopus55 WoS45 Europe PMC39
2020 Frölich, S., Robker, R., & Russell, D. (2020). Development of automated microscopy-assisted high-content multiparametric assays for cell cycle staging and foci quantitation. Cytometry A, 97(4), 378-393.
DOI Scopus5 WoS4 Europe PMC4
2020 Mrozik, K. M., Cheong, C. M., Hewett, D. R., Noll, J. E., Opperman, K. S., Adwal, A., . . . Zannettino, A. C. W. (2020). LCRF-0006, a small molecule mimetic of the N-cadherin antagonist peptide ADH-1, synergistically increases multiple myeloma response to bortezomib.. FASEB Bioadv, 2(6), 339-353.
DOI Scopus5 WoS6 Europe PMC9
2019 Tan, I. A., Frewin, K., Ricciardelli, C., & Russell, D. L. (2019). ADAMTS1 promotes adhesion to extracellular matrix proteins and predicts prognosis in early stage breast cancer patients. Cellular Physiology and Biochemistry, 52(6), 1553-1568.
DOI Scopus13 Europe PMC13
2019 Dinh, D. T., Breen, J., Akison, L. K., DeMayo, F. J., Brown, H. M., Robker, R. L., & Russell, D. L. (2019). Tissue-specific progesterone receptor-chromatin binding and the regulation of progesterone-dependent gene expression. Scientific Reports, 9(1), 11966-1-11966-14.
DOI Scopus38 WoS35 Europe PMC34
2018 Robker, R., Hennebold, J., & Russell, D. (2018). Coordination of ovulation and oocyte maturation: a good egg at the right time. Endocrinology, 159(9), 3209-3218.
DOI Scopus148 WoS132 Europe PMC126
2018 Akison, L., Robertson, S., Gonzalez, M., Richards, J., Smith, C., Russell, D., & Robker, R. (2018). Regulation of the ovarian inflammatory response at ovulation by nuclear progesterone receptor. American Journal of Reproductive Immunology, 79(6), e12835-1-e12835-12.
DOI Scopus32 WoS33 Europe PMC22
2018 Brown, C. Y., Dayan, S., Wong, S. W., Kaczmarek, A. K., Hope, C. M., Pederson, S. M., . . . Barry, S. C. (2018). FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1. Oncotarget, 9(45), 27708-27727.
DOI Scopus20 Europe PMC18
2018 Sutherland, J., Frost, E., Ford, E., Peters, A., Reed, N., Seldon, A., . . . McLaughlin, E. (2018). Janus kinase JAK1 maintains the ovarian reserve of primordial follicles in the mouse ovary. Molecular Human Reproduction, 24(11), 533-542.
DOI Scopus32 WoS31 Europe PMC28
2017 Glynn, D., Heng, K., Russell, D., Sharkey, D., Robertson, S., Anand-Ivell, R., & Ivell, R. (2017). Male seminal relaxin contributes to induction of the post-mating cytokine response in the female mouse uterus. Frontiers in Physiology, 8(422), 422-1-422-12.
DOI Scopus10 WoS8 Europe PMC9
2017 Brown, H., Dunning, K., Sutton-McDowall, M., Gilchrist, R., Thompson, J., & Russell, D. (2017). Failure to launch: aberrant cumulus gene expression during oocyte in vitro maturation. Reproduction, 153(3), R109-R120.
DOI Scopus50 WoS46 Europe PMC38
2016 Moran, L., Spencer, L., Russell, D., Hull, M., Robertson, S., Varcoe, T., . . . Rodgers, R. (2016). Research priorities for fertility and conception research as identified by multidisciplinary health care practitioners and researchers. Nutrients, 8(1), 35-1-35-8.
DOI Scopus6 WoS5 Europe PMC6
2016 Russell, D., Gilchrist, R., Brown, H., & Thompson, J. (2016). Bidirectional communication between cumulus cells and the oocyte: old hands and new players?. Theriogenology, 86(1), 62-68.
DOI Scopus183 WoS162 Europe PMC132
2016 Robker, R. L., & Russell, D. L. (2016). A Primate-Specific Mediator of Ovulation?. Endocrinology, 157(11), 4209-4211.
DOI Scopus1 WoS1 Europe PMC1
2015 Russell, D. L., & Rodgers, R. J. (2015). Riding the wave: Determining the hierarchy of ovarian follicle activation. Biology of Reproduction, 93(4), 2 pages.
DOI Scopus1 WoS1 Europe PMC1
2015 Ceko, M., Hummitzsch, K., Hatzirodos, N., Bonner, W., Aitken, J., Russell, D., . . . Harris, H. (2015). X-Ray fluorescence imaging and other analyses identify selenium and GPX1 as important in female reproductive function. Metallomics, 7(1), 71-82.
DOI Scopus66 WoS61 Europe PMC39
2015 Ceko, M. J., Hummitzsch, K., Hatzirodos, N., Bonner, W. M., Aitken, J. B., Russell, D. L., . . . Harris, H. H. (2015). Erratum: X-Ray fluorescence imaging and other analyses identify selenium and GPX1 as important in female reproductive function (Metallomics (2014) DOI:10.1039/c4mt00228h). Metallomics, 7(1), 188.
DOI Scopus12 WoS11 Europe PMC11
2015 Hummitzsch, K., Anderson, R., Wilhelm, D., Wu, J., Telfer, E., Russell, D., . . . Rodgers, R. (2015). Stem cells, progenitor cells, and lineage decisions in the ovary. Endocrine Reviews, 36(1), 65-91.
DOI Scopus107 WoS100 Europe PMC87
2015 Brown, H., Anastasi, M., Frank, L., Kind, K., Richani, D., Robker, R., . . . Thompson, J. (2015). Hemoglobin: a gas transport molecule that is hormonally regulated in the ovarian follicle in mice and humans. Biology of reproduction, 92(1), 26-1-26-10.
DOI Scopus37 WoS33 Europe PMC25
2015 Wu, L., Russell, D., Wong, S., Chen, M., Tsai, T., St John, J., . . . Robker, R. (2015). Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors. Development, 142(4), 681-691.
DOI Scopus242 WoS225 Europe PMC193
2015 Russell, D., Brown, H., & Dunning, K. (2015). ADAMTS proteases in fertility. Matrix Biology, 44-46, 54-63.
DOI Scopus68 WoS63 Europe PMC49
2015 Dunning, K., Watson, L., Zhang, V., Brown, H., Kaczmarek, A., Robker, R., & Russell, D. (2015). Activation of mouse cumulus-oocyte complex maturation in vitro through EGF-like activity of versican. Biology of Reproduction, 92(5), 116-1-116-10.
DOI Scopus32 WoS29 Europe PMC25
2015 Thompson, J., Brown, H., Kind, K., & Russell, D. (2015). The ovarian antral follicle: living on the edge of hypoxia or not?. Biology of Reproduction, 92(6), 153-1-153-6.
DOI Scopus58 WoS52 Europe PMC39
2015 Andraweera, P., Gatford, K., Dekker, G., Leemaqz, S., Russell, D., Thompson, S., . . . Roberts, C. (2015). Insulin family polymorphisms in pregnancies complicated by small for gestational age infants. Molecular Human Reproduction, 21(9), 745-752.
DOI Scopus5 WoS3 Europe PMC2
2015 Kind, K., Tam, K., Banwell, K., Gauld, A., Russell, D., Macpherson, A., . . . Thompson, J. (2015). Oxygen-regulated gene expression in murine cumulus cells. Reproduction, Fertility and Development, 27(2), 407-418.
DOI Scopus17 WoS17 Europe PMC13
2014 Robker, R., Watson, L., Robertson, S., Dunning, K., McLaughlin, E., & Russell, D. (2014). Identification of sites of STAT3 action in the female reproductive tract through conditional gene deletion. PLoS One, 9(7), e101182-1-e101182-9.
DOI Scopus28 WoS25 Europe PMC22
2014 Lim, S., Ricciardelli, C., Oehler, M., De Arao Tan, I., Russell, D., & Grützner, F. (2014). Overexpression of piRNA pathway genes in epithelial ovarian cancer. PLoS One, 9(6), e99687-1-e99687-11.
DOI Scopus57 WoS53 Europe PMC46
2014 Akison, L., Boden, M., Kennaway, D., Russell, D., & Robker, R. (2014). Progesterone receptor-dependent regulation of genes in the oviducts of female mice. Physiological Genomics, 46(16), 583-592.
DOI Scopus32 WoS33 Europe PMC28
2014 Dunning, K., Russell, D., & Robker, R. (2014). Lipids and oocyte developmental competence: the role of fatty acids and β-oxidation. Reproduction, 148(1), R15-R27.
DOI Scopus378 WoS363 Europe PMC280
2014 Frank, L., Sutton-McDowall, M., Brown, H., Russell, D., Gilchrist, R., & Thompson, J. (2014). Hyperglycaemic conditions perturb mouse oocyte in vitro developmental competence via beta-O-linked glycosylation of Heat shock protein 90. Human Reproduction, 29(6), 1292-1303.
DOI Scopus33 WoS31 Europe PMC29
2014 Ceko, M., Hummitzsch, K., Hatzirodos, N., Bonner, W., Aitken, J., Russell, D., . . . Harris, H. (2014). Correction: X-Ray fluorescence imaging and other analyses identify selenium and GPX1 as important in female reproductive function.. Metallomics : integrated biometal science, 7(1), 188.
DOI
2014 Dunning, K., Anastasi, M., Zhang, V., Russell, D., & Robker, R. (2014). Regulation of fatty acid oxidation in mouse cumulus-oocyte complexes during maturation and modulation by PPAR agonists. PLoS One, 9(2), e87327-1-e87327-11.
DOI Scopus131 WoS125 Europe PMC112
2014 Brown, H., & Russell, D. (2014). Blood and lymphatic vasculature in the ovary: development, function and disease. Human Reproduction Update, 20(1), 29-39.
DOI Scopus79 WoS75 Europe PMC71
2013 Tan, I., Ricciardelli, C., & Russell, D. (2013). The metalloproteinase ADAMTS1: A comprehensive review of its role in tumorigenic and metastatic pathways. International Journal of Cancer, 133(10), 2263-2276.
DOI Scopus73 WoS67 Europe PMC62
2013 Frank, L., McDowall, M., Russell, D., Wang, X., Inglis, D., Gilchrist, R., & Thompson, J. (2013). Effect of varying glucose and glucosamine concentration in vitro on mouse oocyte maturation and developmental competence. Reproduction Fertility and Development, 25(8), 1095-1104.
DOI Scopus16 WoS14 Europe PMC12
2013 Kind, K., Banwell, K., Gebhardt, K., Macpherson, A., Gauld, A., Russell, D., & Thompson, J. (2013). Microarray analysis of mRNA from cumulus cells following in vivo or in vitro maturation of mouse cumulus-oocyte complexes. Reproduction Fertility and Development, 25(2), 426-438.
DOI Scopus35 WoS33 Europe PMC29
2012 Watson, L., Mottershead, D., Dunning, K., Robker, R., Gilchrist, R., & Russell, D. (2012). Heparan sulfate proteoglycans regulate responses to oocyte paracrine signals in ovarian follicle morphogenesis. Endocrinology, 153(9), 4544-4555.
DOI Scopus53 WoS52 Europe PMC49
2012 Akison, L., Alvino, E., Dunning, K., Robker, R., & Russell, D. (2012). Transient invasive migration in mouse cumulus oocyte complexes induced at ovulation by luteinizing hormone. Biology of Reproduction, 86(4), 1-8.
DOI Scopus46 WoS45 Europe PMC43
2012 Wu, L., Russell, D., Norman, R., & Robker, R. (2012). Endoplasmic reticulum (ER) stress in cumulus-oocyte complexes impairs pentraxin-3 secretion, mitochondrial membrane potential (Δᴪm), and embryo development. Molecular Endocrinology, 26(4), 562-573.
DOI Scopus129 WoS122 Europe PMC106
2012 Sutherland, J., Keightley, R., Nixon, B., Roman, S., Robker, R., Russell, D., & McLaughlin, E. (2012). Suppressor of cytokine signaling 4 (SOCS4): moderator of ovarian primordial follicle activation. Journal of Cellular Physiology, 227(3), 1188-1198.
DOI Scopus42 WoS43 Europe PMC36
2012 Dunning, K., Watson, L., Sharkey, D., Brown, H., Norman, R., Thompson, J., . . . Russell, D. (2012). Molecular filtration properties of the mouse expanded cumulus matrix: controlled supply of metabolites and extracellular signals to cumulus cells and the oocyte. Biology of Reproduction, 87(4), 1-10.
DOI Scopus23 WoS23 Europe PMC20
2011 Ricciardelli, C., Frewin, K., Tan, I., Williams, E., Opeskin, K., Pritchard, M., . . . Russell, D. (2011). The ADAMTS1 protease gene is required for mammary tumor growth and metastasis. American Journal of Pathology, 179(6), 3075-3085.
DOI Scopus68 WoS58 Europe PMC63
2011 Dunning, K., Akison, L., Russell, D., Norman, R., & Robker, R. (2011). Increased beta-oxidation and improved oocyte developmental competence in response to L-Carnitine during ovarian in vitro follicle development in mice. Biology of Reproduction, 85(3), 548-555.
DOI Scopus107 WoS100 Europe PMC91
2011 Gebhardt, K., Inglis, D., Dunning, K., Lane, M., & Russell, D. (2011). Human cumulus cell gene expression as a biomarker of pregnancy outcome after single embryo transfer. Fertility and Sterility, 96(1), 47-54.
DOI Scopus168 WoS148 Europe PMC131
2010 Dunning, K., Cashman, K., Russell, D., Thompson, J., Norman, R., & Robker, R. (2010). Beta-oxidation is essential for mouse oocyte developmental competence and early embryo development. Biology of Reproduction, 83(6), 909-918.
DOI Scopus369 WoS355 Europe PMC301
2010 Linyan Wu, L., Dunning, K., Yang, X., Russell, D., Lane, M., Norman, R., & Robker, R. (2010). High-fat diet causes lipotoxicity responses in cumulus-oocyte complexes and decreased fertilization rates. Endocrinology, 151(11), 5438-5445.
DOI Scopus313 WoS284 Europe PMC244
2010 Brown, H., Robker, R., & Russell, D. (2010). Development and hormonal regulation of the ovarian lymphatic vasculature. Endocrinology, 151(11), 5446-5455.
DOI Scopus55 WoS49 Europe PMC47
2010 Yang, X., Dunning, K., Linyan Wu, L., Hickey, T., Norman, R., Russell, D., . . . Robker, R. (2010). Identification of Perilipin-2 as a lipid droplet protein regulated in oocytes during maturation. Reproduction Fertility and Development, 22(8), 1262-1271.
DOI Scopus50 WoS47 Europe PMC43
2010 Brown, H., Dunning, K., Robker, R., Boerboom, D., Pritchard, M., Lane, M., & Russell, D. (2010). ADAMTS1 cleavage of versican mediates essential structural remodeling of the ovarian follicle and cumulus-oocyte matrix during ovulation in mice. Biology of Reproduction, 83(4), 549-557.
DOI Scopus141 WoS125 Europe PMC119
2010 Sasseville, M., Ritter, L., Nguyen, T., Liu, F., Mottershead, D., Russell, D., & Gilchrist, R. (2010). Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells. Journal of Cell Science, 123(18), 3166-3176.
DOI Scopus60 WoS54 Europe PMC51
2010 Tam, K., Russell, D., Peet, D., Bracken, C., Rodgers, R., Thompson, J., & Kind, K. (2010). Hormonally regulated follicle differentiation and luteinization in the mouse is associated with hypoxia inducible factor activity. Molecular and Cellular Endocrinology, 327(1-2), 47-55.
DOI Scopus44 WoS42 Europe PMC36
2010 Gebhardt, K., Feil, D., Lane, M., & Russell, D. (2010). Predicting Pregnancy Success-Evaluation of Cumulus Cell Gene Expression Following Single Embryo Transfer. AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 50, 23.
2009 Robker, R., Akison, L., & Russell, D. (2009). Control of oocyte release by progesterone receptor-regulated gene expression. Nuclear Receptor Signaling, 7(1), 1-12.
DOI Scopus93 Europe PMC63
2009 Robker, R., Akison, L., Bennett, B., Thrupp, P., Chura, L., Russell, D., . . . Norman, R. (2009). Obese Women Exhibit Differences in Ovarian Metabolites, Hormones, and Gene Expression Compared with Moderate-Weight Women. Journal of Clinical Endocrinology and Metabolism, 94(5), 1533-1540.
DOI Scopus341 WoS288 Europe PMC250
2009 Ricciardelli, C., Sakko, A., Ween, M., Russell, D., & Horsfall, D. (2009). The biological role and regulation of versican levels in cancer. Cancer and Metastasis Reviews, 28(1-2), 233-245.
DOI Scopus196 WoS184 Europe PMC168
2007 Dunning, K., Lane, M., Brown, H., Yeo, C., Robker, R., & Russell, D. (2007). Altered composition of the cumulus-oocyte complex matrix during in vitro maturation of oocytes. Human Reproduction, 22(11), 2842-2850.
DOI Scopus70 WoS62 Europe PMC53
2007 Banwell, K., Lane, M., Russell, D., Kind, K., & Thompson, J. (2007). Oxygen concentration during mouse oocyte in vitro maturation affects embryo and fetal development. Human Reproduction, 22(10), 2768-2775.
DOI Scopus88 WoS83 Europe PMC67
2007 Russell, D., & Robker, R. (2007). Molecular mechanisms of ovulation: co-ordination through the cumulus complex. Human Reproduction Update, 13(3), 289-312.
DOI Scopus362 WoS325 Europe PMC270
2007 Ricciardelli, C., Russell, D., Ween, M., Mayne, K., Suwiwat, S., Byers, S., . . . Horsfall, D. (2007). Formation of hyaluronan- and versican-rich pericellular matrix by prostate cancer cells promotes cell motility. Journal of Biological Chemistry, 282(14), 10814-10825.
DOI Scopus135 WoS133 Europe PMC111
2006 Brown, H., Dunning, K., Robker, R., Pritchard, M., & Russell, D. (2006). Requirement for ADAMTS-1 in extracellular matrix remodeling during ovarian folliculogenesis and lymphangiogenesis. Developmental Biology, 300(2), 699-709.
DOI Scopus114 WoS103 Europe PMC100
2006 Russell, D., & Salustri, A. (2006). Extracellular matrix of the cumulus-oocyte complex. Seminars in Reproductive Medicine, 24(4), 217-227.
DOI Scopus152 WoS135 Europe PMC114
2005 Brown, H., Pritchard, M., & Russell, D. (2005). Early ovarian follicle dysgenesis in a disintegrin and metalloproteinase with thrombospondin motifs type 1 (ADAMTS-1) null mice. Reproduction Fertility and Development, 17(9), 87.
DOI
2005 Russell, D. (2005). The cumulus matrix in ovulation: inert packaging or active delivery vehicle for the oocyte?. Reproduction Fertility and Development, 17(9), 69.
DOI
2004 Doyle, K., Russell, D., Sriraman, V., & Richards, J. (2004). Coordinate transcription of the ADAMTS-1 gene by luteinizing hormone and progesterone receptor. Molecular Endocrinology, 18(10), 2463-2478.
DOI Scopus116 WoS108 Europe PMC96
2004 Mittaz, L., Russell, D., Wilson, T., Brasted, M., Tkalcevic, J., Salamonsen, L., . . . Pritchard, M. (2004). Adamts-1 is essential for the development and function of the urogenital system. Biology of Reproduction, 70(4), 1096-1105.
DOI Scopus171 WoS156 Europe PMC136
2003 Rodgers, R., Irving-Rodgers, H., & Russell, D. (2003). Extracellular matrix of the developing ovarian follicle. Reproduction, 126(4), 415-424.
DOI Scopus210 WoS195 Europe PMC169
2003 Russell, D., Doyle, K., Gonzales-Robayna, I., Pipaon, C., & Richards, J. (2003). Egr-1 induction in rat granulosa cells by follicle-stimulating hormone and luteinizing hormone: Combinatorial regulation by transcription factors cyclic adenosine 3' 5'- monophosphate regulatory element binding protein serum response factor Sp1. Molecular Endocrinology, 17(4), 520-533.
DOI Scopus95 WoS89 Europe PMC77
2003 Boerboom, D., Russell, D., Richards, J., & Sirois, J. (2003). Regulation of transcripts encoding ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin-like motifs-1) and progesterone receptor by human chorionic gonadotropin in equine preovulatory follicles. Journal of Molecular Endocrinology, 31(3), 473-485.
DOI Scopus47 WoS46 Europe PMC32
2003 Ochsner, S., Russell, D., Day, A., Breyer, R., & Richards, J. (2003). Decreased expression of tumor necrosis factor-α-stimulated gene 6 in cumulus cells of the cyclooxygenase-2 and EP2 null mice. Endocrinology, 144(3), 1008-1019.
DOI Scopus134 WoS125 Europe PMC100
2003 Russell, D., Ochsner, S., Hsieh, M., Mulders, S., & Richards, J. (2003). Hormone-regulated expression and localization of versican in the rodent ovary. Endocrinology, 144(3), 1020-1031.
DOI Scopus125 WoS122 Europe PMC101
2003 Russell, D., Doyle, K., Ochsner, S., Sandy, J., & Richards, J. (2003). Processing and localization of ADAMTS-1 and proteolytic cleavage of versican during cumulus matrix expansion and ovulation. Journal of Biological Chemistry, 278(43), 42330-42339.
DOI Scopus243 WoS227 Europe PMC199
2003 Abkevich, V., Camp, N. J., Hensel, C. H., Neff, C. D., Russell, D. L., Hughes, D. C., . . . Cannon-Albright, L. (2003). Predisposition locus for major depression at chromosome 12q22-12q23.2. AMERICAN JOURNAL OF HUMAN GENETICS, 73(6), 1271-1281.
DOI WoS146 Europe PMC124
2002 Stone, S., Abkevich, V., Hunt, S. C., Gutin, A., Russell, D. L., Neff, C. D., . . . Shattuck, D. (2002). A major predisposition locus for severe obesity, at 4p15-p14. AMERICAN JOURNAL OF HUMAN GENETICS, 70(6), 1459-1468.
DOI WoS108 Europe PMC88
2002 Richards, J., Russell, D., Ochsner, S., & Espey, L. (2002). Ovulation: new dimensions and new regulators of the inflammatory-like response. Annual Review of Physiology, 64(1), 69-92.
DOI Scopus396 WoS346 Europe PMC288
2002 Richards, J., Russell, D., Ochsner, S., Hsieh, M., Doyle, K., Falender, A., . . . Sharma, S. (2002). Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization. Recent Progress in Hormone Research, 57(1), 195-220.
DOI Scopus377 WoS335 Europe PMC282
2001 Hunt, S. C., Abkevich, V., Hensel, C. H., Gutin, A., Neff, C. D., Russell, D. L., . . . Stone, S. (2001). Linkage of body mass index to chromosome 20 in Utah pedigrees. HUMAN GENETICS, 109(3), 279-285.
DOI WoS43 Europe PMC39
2000 Yoshioka, S., Ochsner, S., Russell, D. L., Ujioka, T., Fujii, S., Richards, J. S., & Espey, L. L. (2000). Expression of tumor necrosis factor-stimulated gene-6 in the rat ovary in response to an ovulatory dose of gonadotropin. Endocrinology, 141(11), 4114-4119.
DOI Scopus84 WoS80 Europe PMC60
2000 Robker, R. L., Russell, D. L., Espey, L. L., Lydon, J. P., O'Malley, B. W., & Richards, J. S. (2000). Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases. Proceedings of the National Academy of Sciences of the United States of America, 97(9), 4689-4694.
DOI Scopus478 WoS445 Europe PMC366
2000 Espey, L. L., Ujioka, T., Russell, D. L., Skelsey, M., Vladu, B., Robker, R. L., . . . Richards, J. S. (2000). Induction of early growth response protein-1 gene expression in the rat ovary in response to an ovulatory dose of human chorionic gonadotropin. Endocrinology, 141(7), 2385-2391.
DOI Scopus80 WoS75 Europe PMC60
2000 Robker, R. L., Russell, D. L., Yoshioka, S., Sharma, S. C., Lydon, J. P., O'Malley, B. W., . . . Richards, J. S. (2000). Ovulation: a multi-gene, multi-step process. Steroids, 65(10-11), 559-570.
DOI Scopus139 WoS134 Europe PMC98
2000 Ujioka, T., Russell, D. L., Okamura, H., Richards, J. S., & Espey, L. L. (2000). Expression of regulator of G-protein signaling protein-2 gene in the rat ovary at the time of ovulation. Biology of Reproduction, 63(5), 1513-1517.
DOI Scopus41 WoS38 Europe PMC34
2000 Espey, L. L., Yoshioka, S., Russell, D. L., Robker, R. L., Fujii, S., & Richards, J. A. S. (2000). Ovarian expression of a disintegrin and metalloproteinase with thrombospondin motifs during ovulation in the gonadotropin-primed immature rat. Biology of Reproduction, 62(4), 1090-1095.
DOI Scopus130 WoS116 Europe PMC94
2000 Yoshioka, S. (2000). Expression of Tumor Necrosis Factor-Stimulated Gene-6 in the Rat Ovary in Response to an Ovulatory Dose of Gonadotropin. Endocrinology, 141(11), 4114-4119.
DOI
1999 Russell, D. L. (1999). Differentiation-Dependent Prolactin Responsiveness and Stat (Signal Transducers and Activators of Transcription) Signaling in Rat Ovarian Cells. Molecular Endocrinology, 13(12), 2049-2064.
DOI
1999 Russell, D. L., & Richards, J. A. S. (1999). Differentiation-dependent prolactin responsiveness and stat (signal transducers and activators of transcription) signaling in rat ovarian cells. Molecular Endocrinology, 13(12), 2049-2064.
DOI Scopus68 WoS62 Europe PMC48
1996 Russell, D. L., Norman, R. L., Dajee, M., Liu, X., Henninghausen, L., & Richards, J. A. S. (1996). Prolactin-induced activation and binding of stat proteins to the IL-6RE of the α2-macroglobulin (α2M) promoter: Relation to the expression of α2M in the rat ovary. Biology of Reproduction, 55(5), 1029-1038.
DOI Scopus40 WoS42 Europe PMC31
1996 McConnell, D. T., Wilson, B. J., Russell, D., Parkin, D. E., & Kitchener, H. C. (1996). Rising incidence of vulval cancer in north east Scotland 1974-94: A population based study. International Journal of Gynecological Cancer, 6(4), 309-312.
DOI Scopus7
1996 Russell, D. L., & Kim, K. H. (1996). Expression of triosephosphate isomerase transcripts in rat testis: Evidence for retinol regulation and a novel germ cell transcript. BIOLOGY OF REPRODUCTION, 55(1), 11-18.
DOI WoS24 Europe PMC22
1995 Russell, D. L., Salamonsen, L. A., & Findlay, J. K. (1995). Immunization against the N-Terminal Peptide of the Inhihin α43-Subunit (αN) Disrupts Tissue Remodeling and the Increase in Matrix Metalloproteinase-2 during Ovulation. Endocrinology, 136(8), 3657-3664.
DOI Scopus47 Europe PMC24
1995 RUSSELL, D. L., SALAMONSEN, L. A., & FINDLAY, J. K. (1995). IMMUNIZATION AGAINST THE N-TERMINAL PEPTIDE OF THE INHIBIN ALPHA-43-SUBUNIT (ALPHA-N) DISRUPTS TISSUE REMODELING AND THE INCREASE IN MATRIX METALLOPROTEINASE-2 DURING OVULATION. ENDOCRINOLOGY, 136(8), 3657-3664.
DOI WoS48
1995 Russell, D. L., & Findlay, J. K. (1995). The N-terminal peptide of the inhibin α subunit. What are its endocrine and paracrine roles?. Trends in Endocrinology and Metabolism, 6(9-10), 305-311.
DOI Scopus5 WoS6 Europe PMC3
1994 Findlay, J. K., Russell, D. L., Doughton, B., Tsonis, C. G., Borchers, C., & Forage, R. G. (1994). Effect of active immunization against the amino-terminal peptide (An) of the alpha 43 kda subunit of inhibin (α43) on fertility of ewes. Reproduction, Fertility and Development, 6(2), 265-267.
DOI Scopus19 WoS19 Europe PMC7
1994 Russell, D. L., Doughton, B. W., Tsonis, C. G., & Findlay, J. K. (1994). Pituitary and ovarian function in ewes immunized against the amino-terminal peptide (αN) of the inhibin α<inf>43</inf>-subunit. Journal of Reproduction and Fertility, 100(1), 115-122.
DOI Scopus11 WoS11 Europe PMC3
1993 Russell, D. L., Manalo, G. G., Findlay, J. K., & Salamonsen, L. A. (1993). Binding sites for interferons on ovine and human endometrial membranes. Reproduction Fertility and Development, 5(2), 219-227.
DOI Scopus6 WoS7 Europe PMC4
1992 Findlay, J. K., Robertson, D. M., Clarke, I. J., Klein, R., Doughton, B. W., Xiao, S., . . . Shukovski, L. (1992). Hormonal regulation of reproduction - general concepts. Animal Reproduction Science, 28(1-4), 319-328.
DOI Scopus15 WoS14
1991 Findlay, J. K., Doughton, B. W., & Russell, D. L. (1991). Peripheral concentrations of immunoreactive inhibin during pregnancy and parturition in the ewe. Reproduction, Fertility and Development, 3(5), 543-549.
DOI Scopus8 WoS10 Europe PMC2
1986 CONSIGLI, R. A., RUSSELL, D. L., & WILSON, M. E. (1986). THE BIOCHEMISTRY AND MOLECULAR-BIOLOGY OF THE GRANULOSIS-VIRUS THAT INFECTS PLODIA-INTERPUNCTELLA. CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY, 131, 69-101.
- Chin, L., Kieffer, T., Chan, H. Y., Prins, J. R., Russell, D., Davies, M., & Robertson, S. (n.d.). Clomiphene citrate administered in peri-conception phase causes fetal loss and developmental impairment in mice.
DOI

Year Citation
2019 Findlay, J. K., Dunning, K. R., Gilchrist, R. B., Hutt, K. J., Russell, D. L., & Walters, K. A. (2019). Follicle Selection in Mammalian Ovaries. In P. Leung, & E. Adashi (Eds.), The Ovary (3 ed., pp. 3-21). United Kingdom: Academic Press.
DOI
2019 Russell, D., & Robker, R. (2019). Ovulation: The Coordination of Intrafollicular Networks to Ensure Oocyte Release. In P. Leung, & E. Adashi (Eds.), The Ovary (3 ed., pp. 217-234). United Kingdom: Academic Press.
2018 Russell, D. L., & Robker, R. L. (2018). Cumulus cells. In M. K. Skinner (Ed.), Encyclopedia of Reproduction (pp. 43-46). Academic Press.
DOI Scopus6
2018 Russell, D. L., & Robker, R. L. (2018). Cumulus Cells. In Encyclopedia of Reproduction Volume 1 6 Second Edition (Vol. 2, pp. 43-46).
DOI
2009 Ricciardelli, C., Sakko, A., Ween, M., Russell, D., & Horsfall, D. (2009). The proteoglycan versican: an important regulator of cell locomotion in development and disease. In T. Abreu, & G. Silva (Eds.), Cell movement : new research trends (pp. 1-19). Nova Science Publishers.

Year Citation
2015 Muhling, J., Russell, D., & Barry, S. (2015). USE OF VIRAL VECTORS IN PRIMARY CELLS. In JOURNAL OF GENE MEDICINE Vol. 17 (pp. 214-215). Univ Melbourne, Univ Coll, Parkville, AUSTRALIA: WILEY-BLACKWELL.
2011 Gebhardt, K. M., Feil, D. K., Dunning, K. R., Lane, M., & Russell, D. L. (2011). Human cumulus cell gene expression as a biomarker of pregnancy outcome after single embryo transfer. In Revista Iberoamericana De Fertilidad Y Reproduccion Humana Vol. 28 (pp. 7).
2011 Russell, D. L., Matson, L. N., Dunning, K. R., Thompson, J. G., Robker, R. L., & Gilchrist, R. B. (2011). Patterning the Response to Oocyte Signals in Ovarian Follicle Morphogenesis.. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION.
2011 Akison, L. K., Alvino, E. R., Dunning, K. R., Robker, R. L., & Russell, D. L. (2011). Migratory, Invasive and Adhesive Phenotypes Are Transiently Induced in the Cumulus Oocyte Complex at Ovulation.. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION.
2011 Frank, L. A., Sutton-McDowall, M. L., Russell, D. L., Gilchrist, R. B., & Thompson, J. G. (2011). Proteomic Analysis of Beta-O-Linked Glycosylated Proteins Extracted from Glucosamine-Treated Mouse Cumulus-Oocyte Complexes Reveals HSP90 Glycosylation as a Potential Regulator of Oocyte Competence. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION.
WoS1
2010 Robker, R. L., Akison, L. K., Richards, J. S., Smith, C. W., & Russell, D. L. (2010). The Inflammatory Response at Ovulation Is Altered in Ovaries of Progesterone Receptor Null (PRKO) Mice. In BIOLOGY OF REPRODUCTION (pp. 71). Milwaukee, WI: SOC STUDY REPRODUCTION.
2010 Dunning, K. R., Cashman, K., Russell, D. L., Thompson, J., Norman, R., & Robker, R. L. (2010). Increased Beta-Oxidation, ATP Levels, and Improved Oocyte Developmental Competence in Response to L-Carnitine. In BIOLOGY OF REPRODUCTION (pp. 84). Milwaukee, WI: SOC STUDY REPRODUCTION.
2010 Wu, L. L., Dunning, K. R., Yang, X., Russell, D. L., Norman, R. J., & Robker, R. L. (2010). Oocytes Exhibit Lipid Accumulation, Endoplasmic Reticulum Stress, Mitochondrial Dysfunction, and Apoptosis in Response to High Fat Diet. In BIOLOGY OF REPRODUCTION (pp. 91). Milwaukee, WI: SOC STUDY REPRODUCTION.
WoS1
2009 Dunning, K. R., Cashman, K., Russell, D. L., Norman, R. N., & Robker, R. L. (2009). The Role of Beta-Oxidation During Oocyte Maturation and Embryo Development.. In BIOLOGY OF REPRODUCTION (pp. 54). Pittsburgh, PA: SOC STUDY REPRODUCTION.
2009 Ricciardelli, C., Frewin, K., Ingman, W., & Russell, D. L. (2009). Role of Adamts1 in mammary cancer growth and metastasis. In CLINICAL & EXPERIMENTAL METASTASIS Vol. 26 (pp. 922). SPRINGER.
2009 Sasseville, M., Nguyen, T. M., Ritter, L. J., Russell, D. L., & Gilchrist, R. B. (2009). Oocyte/GDF9 Regulation of Granulosa/Cumulus Cell Functions Requires EGF Receptor/MAPK3/1 Signaling.. In BIOLOGY OF REPRODUCTION (pp. 72). Pittsburgh, PA: SOC STUDY REPRODUCTION.
WoS2
2009 Russell, D. L., Gebhardt, K., Fed, D., Robker, R. L., & Lane, M. (2009). Novel Cumulus Cell Biomarkers of an Oocyte's Potential to Achieve Pregnancy. In BIOLOGY OF REPRODUCTION (pp. 91). Pittsburgh, PA: SOC STUDY REPRODUCTION.
2008 Russell, D., Brown, H., Alvino, E., & Robker, R. (2008). Involvement of blood and lymphatic angiogenesis in folliculogenesis and ovulation. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 79). Kona, HI: SOC STUDY REPRODUCTION.
DOI
2008 Tam, K., Russell, D., Kind, K., & Thompson, J. (2008). Post hCG follicle differentiation in the mouse is associated with an increase in hypoxia inducible factor activity. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 127). Kona, HI: SOC STUDY REPRODUCTION.
DOI
2007 Dunning, K., Lane, M., Brown, H., Yeo, C., Thompson, J., Robker, R., & Russell, D. (2007). Altered cumulus oocyte matrix following in vitro maturation of oocytes.. In BIOLOGY OF REPRODUCTION Vol. 77 (pp. 199). San Antonio, TX: SOC STUDY REPRODUCTION.
DOI WoS1
2007 Banwell, K. M., Lane, M., Russell, D. L., Kind, K. L., & Thompson, J. G. (2007). Oxygen concentration during <i>in vitro</i> maturation of murine oocytes influences subsequent fetal and placental outcomes. In REPRODUCTION FERTILITY AND DEVELOPMENT Vol. 19 (pp. 285). CSIRO PUBLISHING.
DOI
2006 Russell, D. L., Brown, H. M., Dunning, K. R., Pritchard, M. A., & Robker, R. L. (2006). Ovarian folliculogenesis and lymphangiogenesis are dependent on ECM remodelling by the protease ADAMTS-1.. In BIOLOGY OF REPRODUCTION (pp. 109). Univ Nebraska Med Ctr, Omaha, NE: SOC STUDY REPRODUCTION.
2005 Russell, D. L., Pritchard, M., & Brown, H. (2005). Oocyte ovulation and oviductal transport: The importance of extracellular, matrix and proteolytic activity in the cumulus complex.. In BIOLOGY OF REPRODUCTION (pp. 110). Ctr Rech Biol Reproduct, Quebec City, CANADA: SOC STUDY REPRODUCTION.
WoS1
2005 Camp-Dotlic, E., Froiland, D., Kind, K., Irving-Rodgers, H., Thompson, J., & Russell, D. (2005). Murine HIF-1a localisation by immunohistochemistry in a mouse reproductive tissue. In Reproduction Fertility and Development Vol. 17 (pp. 129). C S I R O Publishing.
DOI
2005 Banwell, K., Lane, M., Russell, D., Kind, K., & Thompson, J. (2005). Oxygen concentration during in vitro maturation of murine oocytes affects blastocyst cell lineage. In Reproduction Fertility and Development Vol. 17 (pp. 91). C S I R O Publishing.
DOI
2005 Dunning, K., Yeo, C., & Russell, D. (2005). Altered matrix composition of cumulus oocyte complexes following in vitro maturation. In Reproduction Fertility and Development Vol. 17 (pp. 90). C S I R O Publishing.
DOI
2003 Robker, R. L., Smith, C. W., Norman, R. J., & Russell, D. L. (2003). Macrophage migration and luteal regression in ovaries of leukocyte adhesion molecule-deficient (ICAM-1-/-) mice.. In BIOLOGY OF REPRODUCTION Vol. 68 (pp. 307-308). CINCINNATI, OHIO: SOC STUDY REPRODUCTION.
2003 Russell, D. L., Doyle, K. M. H., Ochsner, S. A., Sandy, J. D., Pritchard, M., Mittaz-Crettol, L., & Richards, J. S. (2003). Localization, processing and function of ADAMTS-1 during ovulation.. In BIOLOGY OF REPRODUCTION Vol. 68 (pp. 212). CINCINNATI, OHIO: SOC STUDY REPRODUCTION.
2003 Doyle, K. M. H., Russell, D. L., & Richards, J. S. (2003). Analysis of an LH- and PR-regulated gene in ovulation: ADAMTS-1.. In BIOLOGY OF REPRODUCTION Vol. 68 (pp. 212). CINCINNATI, OHIO: SOC STUDY REPRODUCTION.
2002 Boerboom, D., Russell, D. L., Richards, J. S., & Sirois, J. (2002). Coordinated regulation of transcripts encoding ADAMTS-1 and progesterone receptor in equine preovulatory follicles.. In BIOLOGY OF REPRODUCTION Vol. 66 (pp. 131). SOC STUDY REPRODUCTION.
2002 Russell, D. L., Kronenberg, F., Timms, K. M., McDermott, M. T., DeGrado, J., O'Neill, H. A., . . . Shattuck, D. M. (2002). Germline mutations in angiotensinogen associated with predisposition to type 1 diabetes.. In AMERICAN JOURNAL OF HUMAN GENETICS Vol. 71 (pp. 490). BALTIMORE, MD: CELL PRESS.
2001 Uwaifo, G. I., Nguyen, T. T., Russell, D. L., Nicholson, J. C., Keil, M. F., Goldhar, L., . . . Yanovski, J. A. (2001). Determinants of differences in insulin sensitivity, secretion and clearance of African American and Caucasian children. In OBESITY RESEARCH Vol. 9 (pp. 84S). NORTH AMER ASSOC STUDY OBESITY.
2001 Hunt, S. C., Abkevich, V., Hensel, C. H., Gutin, A., Neff, C. D., Russell, D. L., . . . Stone, S. (2001). Linkage of body mass index to chromosome 20 in Utah pedigrees. In OBESITY RESEARCH Vol. 9 (pp. 71S). NORTH AMER ASSOC STUDY OBESITY.
2001 Doyle, K. M. H., Russell, D. L., & Richards, J. S. (2001). Hormonal regulation of ADAMTS-1 in the rodent ovary.. In BIOLOGY OF REPRODUCTION Vol. 64 (pp. 290-291). SOC STUDY REPRODUCTION.
WoS2
2000 Espey, L. L., Yoshioka, S., Russell, D., Ujioka, T., Vladu, B., Skelsey, M., . . . Richards, J. A. S. (2000). Characterization of ovarian carbonyl reductase gene expression during ovulation in the gonadotropin-primed immature rat. In Biology of Reproduction Vol. 62 (pp. 390-397). PORTLAND, OREGON: SOC STUDY REPRODUCTION.
DOI Scopus38 WoS33 Europe PMC26
2000 Nicholson, J. C., McDuffie, J. R., Russell, D. L., Boyce, K. A., McCann, S., Michael, M., . . . Yanovski, J. A. (2000). Body composition by air displacement plethysmography in African American and Caucasian children. In OBESITY RESEARCH Vol. 8 (pp. 37S). NORTH AMER ASSOC STUDY OBESITY.
1999 Richards, J. A., Robker, R. L., & Russell, D. L. (1999). Ovulation: A multi-gene, multi-step process.. In BIOLOGY OF REPRODUCTION Vol. 60 (pp. 87-88). SOC STUDY REPRODUCTION.
1999 Yoshioka, S., Russell, D., Fujii, S., Richards, J. A. S., & Espey, L. L. (1999). Ovarian expression of a metalloproteinase-disintegrin family protein during ovulation in the PMSG-primed immature rat model.. In BIOLOGY OF REPRODUCTION Vol. 60 (pp. 215). SOC STUDY REPRODUCTION.
WoS1
1998 Richards, J. A. S., Russell, D. L., Robker, R. L., Dajee, M., & Alliston, T. N. (1998). Molecular mechanisms of ovulation and luteinization. In Molecular and Cellular Endocrinology Vol. 145 (pp. 47-54). NETHERLANDS, AMSTERDAM: ELSEVIER IRELAND LTD.
DOI Scopus204 WoS187 Europe PMC141
1997 Russell, D. L., & Richards, J. S. (1997). Causes of infertility in mice with targeted deletion of the PGS-2 gene.. In BIOLOGY OF REPRODUCTION Vol. 56 (pp. 382). SOC STUDY REPRODUCTION.
WoS4
1996 Russell, D. L., & Richards, J. S. (1996). Prolactin signaling in the ovary: Activation and binding of STATs to the IL-6RE of the alpha 2-macroglobulin promoter.. In BIOLOGY OF REPRODUCTION Vol. 54 (pp. 182). SOC STUDY REPRODUCTION.
1996 Selstan, G., Russell, D. L., & Richards, J. S. (1996). Differential activation of stat factors and expression of alpha 2macroglobulin by prolactin in pseudopregnant and pregnant rat ovaries. In BIOLOGY OF REPRODUCTION Vol. 54 (pp. 181). SOC STUDY REPRODUCTION.
1994 FINDLAY, J. K., SHUKOVSKI, L., & RUSSELL, D. L. (1994). THE ROLES OF INHIBIN, ACTIVIN AND FOLLISTATIN IN FOLLICULOGENESIS AND OVULATION. In H. G. Burger, J. Findlay, D. Robertson, D. DeKretser, & F. Petraglia (Eds.), INHIBIN AND INHIBIN-RELATED PROTEINS Vol. 3 (pp. 145-161). SIENA, ITALY: ARES-SERONO SYMPOSIA PUBLICATIONS.
1990 JOHNSTON, R. E., DAVIS, N. L., POLO, J. M., RUSSELL, D. L., PENCE, D. F., MEYER, W. J., . . . SMITH, J. F. (1990). STUDIES OF ALPHAVIRUS VIRULENCE USING FULL-LENGTH CLONES OF SINDBIS AND VENEZUELAN EQUINE ENCEPHALITIS VIRUSES. In M. A. BRINTON, & F. X. HEINZ (Eds.), NEW ASPECTS OF POSITIVE-STRAND RNA VIRUSES (pp. 334-339). VIENNA, AUSTRIA: AMER SOC MICROBIOLOGY.
WoS1

Year Citation
- Roennfeldt, A., Allen, T., Trowbridge, B., Beard, M., Whitelaw, M., Russell, D., . . . Peet, D. (n.d.). Graph Pad prism files of all data published in Roennfeldt et al. (2023). Data points for each experiment represents the mean of an individual replicate (and thus each experiment was completed in triplicate with the mean +/- standard deviation graphed)..
DOI

Year Citation
2025 Emery, A., Blaschuk, O. W., Dinh, D. T., McPhee, T., Becker, R., Abell, A. D., . . . Russell, D. L. (2025). N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation.
DOI WoS1 Europe PMC2
2024 Emery, A., Blaschuk, O. W., Dinh, T. D., McPhee, T., Becker, R., Abell, A. D., . . . Russell, D. L. (2024). N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation.
DOI
2023 Emery, A., Blaschuk, O. W., Dinh, T. D., McPhee, T., Becker, R., Abell, A. D., . . . Russell, D. L. (2023). N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation.
DOI
2023 Allen, T., Roennfeldt, A., Reckdharajkumar, M., Liu, M., Quinn, R., Russell, D., . . . Bersten, D. (2023). dFLASH; dual FLuorescent transcription factor Activity Sensor for Histone integrated live-cell reporting and high-content screening.
DOI

Current National and International Research Support

  • 2019-2021.  New safer contraceptives that block ovulation

    Bill and Melinda Gates Foundation - Grand Challenge Research Grants.  Phase II.  CIA
  • 2019-2022.  Regulation of oocyte maturation and female fertility by functional non-coding RNA.

     NHMRC - Project Grants.  CIA
  • 2017-2019.  New safer contraceptives that block ovulation

    Bill and Melinda Gates Foundation - Grand Challenge Research Grants.  Phase I.  CIA
  • 2018-2020.  Why is there an increased risk of severe adverse perinatal outcomes after the use of clomiphene citrate for infertility treatment?

    NHMRC - Project Grants.  CIF
  • 2018-2020.  Antioxidant enzymes counter reactive oxygen species from steroidogenic cytochrome P450 enzymes in the ovary to limit aneuploidy of embryos.

    NHMRC - Project Grants.  AI
  • 2017-2020.  Re-energising the preimplantation embryo to extend lifetime health

    NHMRC - Project Grants CIC
  • 2016-2021.  Molecular control of female fertility and cancer.

    Research Fellowships.  CIA

Date Role Research Topic Program Degree Type Student Load Student Name
2022 Principal Supervisor Discovering newer safer non-hormonal contraceptives for women Doctor of Philosophy Doctorate Full Time Ms Minnu Jayapal
2022 Co-Supervisor Developing cell-based screening systems to identify small molecule inhibitors of the hypoxic signalling protein FIH, and to investigate the signalling pathways of ovulation. Doctor of Philosophy Doctorate Full Time Miss Alison Elizabeth Roennfeldt
2020 Co-Supervisor Meiotic Drive and Chromosome Segregation Doctor of Philosophy Doctorate Full Time Mr Feng Tang

Date Role Research Topic Program Degree Type Student Load Student Name
2021 - 2024 Co-Supervisor Steroidogenesis, Reactive Oxygen Species and Female Reproduction Doctor of Philosophy Doctorate Full Time Mr Feng Tang
2020 - 2024 Co-Supervisor Stress Fiber Formation and Migration Are Novel PGR-Dependent Pathways Initiated in the Granulosa Cells of the Ovulating Follicle Doctor of Philosophy Doctorate Full Time Miss Kirsten Mary Smith
2019 - 2022 Co-Supervisor Proteins as Therapeutic Targets in Ovulation, Cancer and Antibiotic Resistance Doctor of Philosophy Doctorate Full Time Mr Rouven Becker
2017 - 2021 Co-Supervisor Mitochondrial Function Regulates Telomere Elongation during Embryogenesis Doctor of Philosophy Doctorate Full Time Miss Yasmyn Ellaynah Winstanley
2017 - 2023 Co-Supervisor The effects of the drug BGP-15 on metabolic processes altered by advancing age and oxidative stress on murine fertility Doctor of Philosophy Doctorate Full Time Mr David Thomas Kennedy
2016 - 2020 Principal Supervisor The Molecular Mechanism of Progesterone Receptor in Regulating Gene Expression in Mouse Granulosa Cells during Ovulation Doctor of Philosophy Doctorate Full Time Dr Doan Thao Dinh
2011 - 2013 Co-Supervisor The Role of Nuclear Progesterone Receptor (PGR) in Regulating Gene Expression, Morphology and Function in the Ovary and Oviduct during the Periovulatory Period Doctor of Philosophy Doctorate Full Time Ms Lisa Akison
2009 - 2014 Principal Supervisor Adamts1 is a promoter of metastatic cell behaviour in mammary cancer cells Doctor of Philosophy Doctorate Full Time Miss Izza Maria Doreen De Arao Tan
2009 - 2012 Co-Supervisor The Role of the Hexosamine Biosynthesis Pathway and Beta-O-Linked Glycosylation in Determining Oocyte Developmental Competence Doctor of Philosophy Doctorate Full Time Ms Laura Frank
2008 - 2009 Principal Supervisor Characterisation of the Development and Hormonal Regulation of the Ovarian Lymphatic Vasculature Doctor of Philosophy Doctorate Full Time Prof Hannah Brown
2008 - 2010 Principal Supervisor Identification of Molecular Markers of Pregnancy Success for Assisted Reproduction Doctor of Philosophy Doctorate Full Time Miss Kathryn Gebhardt
2008 - 2011 Co-Supervisor The Role of the Cumulus Oocyte Complex During Ovulation Doctor of Philosophy Doctorate Full Time Dr Emily Alvino
2007 - 2010 Co-Supervisor The Role of Hypoxia Inducible Factors in Regulating Ovarian Function Doctor of Philosophy Doctorate Full Time Miss Kimberley Tam
2006 - 2010 Co-Supervisor Determination of Non-Invasive Viability Markers for Human Embryos in In Vitro Fertilization Doctor of Philosophy Doctorate Part Time Ms Deanne Kate Inglis
2005 - 2008 Principal Supervisor Functional Characterisation of the Cumulus Oocyte Matrix During Maturation of Oocytes Doctor of Philosophy Doctorate Part Time APrf Kylie Dunning

Date Role Board name Institution name Country
2018 - 2021 Director Society for the Study of Reproduction Board of Directors Society for the Study of Reproduction United States

Date Role Committee Institution Country
2016 - ongoing Member AMS Research Committee University of Adelaide Australia
2015 - ongoing Member Robinson Research Institute Executive Council Robinson Research Institute Australia

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