ARC Senior Research Associate
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Kylie Dunning leads the Reproductive Success team within the Robinson Research Institute and the Australian Research Council (ARC) Centre of Excellence for Nanoscale BioPhotonics (CNBP).
Kylie is a reproductive biologist who aspires to use safe, cutting-edge, light-based technologies (also referred to as photonics) to better understand the biology that underpins successful development of the oocyte (egg) and early embryo. With one-in-six Australian couples struggling to start a family without medical intervention, Kylie is committed turning her laboratory discoveries into impact for these couples, engaging early and often with clinical experts to address the greatest clinical challenges.
With a focus on how oocytes (eggs) and embryos create energy, Kylie pioneered the paradigm-shifting research describing the requirement for lipid metabolism by the oocyte and early embryo.
With a drive to see outcomes for patients, Kylie is now using this knowledge and expertise with cutting-edge imaging and diagnostic technologies, to deliver the next generation of tools for the fertility clinic, and agriculture industry. She is leading the way in the development of safe, non-invasive diagnostic technologies that will change the way fertility specialists and embryologists select the best eggs and embryos, which will ultimately improve the experience for all couples seeking fertility care.
See more here:
ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP): http://www.cnbp.org.au
In our team we use safe, cutting-edge, light-based technologies (also referred to as photonics) to better understand the biology that underpins successful development of the oocyte (egg) and early embryo. With one-in-six Australian couples struggling to start a family without medical intervention, we are committed turning our laboratory discoveries into impact for these couples, engaging early and often with clinical experts to address the greatest clinical challenges.
We have a culturally and gender diverse team who are supportive and encouraging of each other. Our team members are Carl Campugan (research assistant), Annie Whitty (part-time research assistant) and postgraduate students: Megan Lim, Cheow (Tiffany) Tan, Suliman Yagoub, Darren Chow, Avi Saini and Hanna McLennan.
Research Project 1
Title: Biophotonic approaches to understanding preimplantation embryo development
Research Project 2
Title: Novel optical assessments of embryo development: can we pick the best embryo?
Project description: Increasingly, people are delaying starting a family until later in life. The expectation of conceiving children is often disrupted by infertility (1 in 6 Australian couples). Such a diagnosis can lead to reduced productivity, financial hardship, relationship breakdown and mental illness. Infertility is typically addressed by in vitro fertilization (IVF). Whilst IVF has seen major advancements, it still faces numerous challenges, most notably low success rates: only 18% of Australian and New Zealand initiated IVF cycles deliver a live birth. One of the reasons for the low success rate is the inability to select the healthiest embryo. In this project you will utilise cutting edge microscopy techniques combined with post-imaging assessments to better understand the pre-implantation embryo development period. You will be comparing normal healthy embryos with poor quality embryos: those which fail to complete the preimplantation period or lead to implantation failure or pregnancy loss. Our research is clinically relevant, and we are passionate about translating outcomes into the human IVF clinic and in agriculture. Don’t hesitate to contact us to discuss further.
Projects available for: Third Year / Honours / HDR
Location: Helen Mayo Building
Research project start: Semester 1 and 2
Special requirements: N/A
2018 Vevo 3100 ultrasound biomicroscope for the Adelaide Biomed city precinct. Ian Potter Foundation Research Grant. Gatford K, Care A, Di Bartolo B, Robertson S, Roberts C, Thompson J, Robker R, Russell D, Hull M, Diener K, Schjenken J, Zhang B, Dunning K, Reynolds P, Bursill C, Tan J, Nicholls S, Verjans J, O'Hare Doig R, Bonder C, Moore E, Howarth G, Ricciardelli C, Lokman N, Mashtoub S, Corbett M ($ 360,000)
2017 Robinson Research Institute Engaging Opportunities Grant The story telling and science of pregnancy loss. CIA H. Brown CIB K Dunning CIC C Roberts ($18,000)
2017 SRB Early Career Researcher Collaborative Research Award ($1500)
2017Robinson Research Institute Career Development Fellowship. CIA: K. Dunning, ($60,000)
2015 Robinson Research Institute Innovation Seed Funding Program. CIA: H. Brown, CIB: M. Nottle, CIC: K. Dunning, CID: K. Gatford. Preventing and Alleviating Infertility: Enabling the best start in life ($25,000)
2012-2017 Discovery Early Career Researcher Award (DECRA). Biomimetic systems for species preservation and fertility restoration ($375,000). CI K. Dunning Grant ID: DE120100304
2012 Channel 7 Children’s Foundation Research Grant [state-wide], CIA: L. Wu, CIB: K. Dunning, CIC: R. Robker, CID: R. Norman.”The impact of lipotoxicity in the ovaries and oocytes of obese women on embryo health” ($48,000)
2011 WCH Foundation Research Project Grant, CIA K. Dunning CIB R. Robker, CIC L. Hull “Modulating Lipid Metabolism to Improve the Growth of Follicles and Oocytes in vitro” ($50,000)
2011 Channel 7 Children’s Foundation Research Grant [state-wide], CIA: K. Dunning CIB: R Robker, Grant ID 11410, $35,000
2009 The Robinson Institute Early Career Research Grant, University of Adelaide ($10,000)
2014-2017 Lecturer, Research Projects in Reproductive Health, University of Adelaide
2015 Lecturer, Human Reproductive Health III, University of Adelaide
2010-2015 Lecturer, Honours Program, School of Paediatrics & Reproductive Health; University of Adelaide
2006-2007 Tutor, Bachelor of Surgery (MBBS) students, University of Adelaide
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