Professor Corinna Van Den Heuvel
Head of School
School of Biomedicine
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Prof. Corinna Van Den Heuvel completed her PhD on the response of amyloid precursor protein following traumatic brain injury (TBI) at the University of Adelaide (UofA) in 1999 and during this time was an active member of the Adelaide Head Injury Group. Following completion of her PhD she was immediately appointed as a lecturer in the Department of Pathology at the UofA in 1999.
Corinna has held numerous leadership positions within the University since this time and is currently the Head of the School of Biomedicine and the Program Director for the Bachelor of Health and Medical Sciences Program (BHlthMedSc). Corinna is an Education Specialist and is a member of the Adelaide Education Academy and has been the recipient of numerous teaching awards. Corinna’s contribution to higher education has been recognised internationally with her appointment in 2018 as a Senior Fellow of Advance HE. She has also been the recipient of numerous teaching and leadership awards including the Executive Dean’s Medal in 2016 and 2020. She was also the recipient of the Stephen Cole the Elder Award for Excellence in Leadership, Support and Enhancement of teaching practice in 2018. Most recently in 2022 she was awarded the University of Adelaide Award for Exceptional Leadership.
She is part of the Translational Neuropathology Laboratory at the UofA and her current research focusses on traumatic brain injury. She also has successful research collaborations with Forensic Science SA and the Centre of Automative Safety Research within the UofA. Her work has been presented both nationally and internationally and published widely in internationally recognised journals and she has received over $1.6 million in category one research funding . She has supervised numerous first class Honours and PhD students to completion and mentored many HDR students and junior academics who are now leading successful academic or research careers both Nationally and Internationally.
Member of the Translational Neuropathology Laboratory at the University of Adelaide and her current research focusses on traumatic brain injury. She also has research collaborations with Forensic Science SA and the Centre for Automative Safety Research. Her work has been presented both nationally and internationally and published widely in internationally recognised journals. She has supervised numerous first class Honours and PhD students.
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Appointments
Date Position Institution name 2023 - ongoing Head, School of Biomedicine The University of Adelaide 2022 - ongoing Head, School of Biomedicine University of Adelaide 2020 - 2022 Interim Head, Adelaide Medical School The University of Adelaide 2019 - 2020 Head, Department of Medical Sciences The University of Adelaide 2018 - ongoing Senior Fellow Advance HE 2018 - ongoing Stephen Cole the Elder Award The University of Adelaide 2018 - 2019 Head Discipline Anatomy and Pathology The University of Adelaide 2016 - ongoing Bachelor of Health and Medical Sciences Program Coordinator The University of Adelaide 2016 - ongoing Bachelor of Health Sciences Program Coordinator The University of Adelaide 2016 - ongoing Member of the Adelaide Education Academy University of Adelaide 2011 - ongoing Associate Professor The University of Adelaide 2005 - 2011 Senior Lecturer The University of Adelaide 2000 - 2005 Lecturer level B University of Adelaide 1999 - 2000 Associate Lecturer University of Adelaide 1994 - 1995 Research Assistant Royal Adelaide Hospital -
Awards and Achievements
Date Type Title Institution Name Country Amount 2018 Award Stephen Cole the Elder Award for Excellence in the Leadership, Support and Enhancement of Teaching Practice The University of Adelaide Australia - 2016 Award Executive Deans Medal The University of Adelaide Australia - 2008 Award Executive Deans Prize for Excellence in Teaching - - - 2001 Award South Australian Brain Foundation’s Elizabeth Penfold Simpson Prize - - $7,500 2000 Award Cairns Society Travel Prize - - $5,000 1998 Award First Prize Medical Staff Society Research Prize Royal Adelaide Hospital - $1,000 1996 Scholarship Benjamin Poulton Scholarship The University of Adelaide - - -
Education
Date Institution name Country Title 1999 The University of Adelaide Australia Doctor of Philosophy (Neuroscience) 1994 The University of Adelaide Australia Bachelor of Health Science (Hons I) 1993 The University of Adelaide Australia Bachelor of Health Science -
Research Interests
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Journals
Year Citation 2024 Stephenson, L., Van Den Heuvel, C., Humphries, M., & Byard, R. W. (2024). Recent trends in an uncommon method of carbon monoxide suicide.. Forensic Sci Med Pathol, 20(3), 863-871.
2024 Stephenson, L., Van Den Heuvel, C., Scott, T., & Byard, R. W. (2024). Difficulties associated with the interpretation of postmortem toxicology. Journal of Analytical Toxicology, 48(6), 405-412.
2024 Hunter, J. W. S., van den Heuvel, C., Stephenson, L., Elborough, L., & Byard, R. W. (2024). Increasing age and lethal opiate use. Medicine, Science and the Law, 5 pages.
2024 O’Donovan, S., van den Heuvel, C., Baldock, M., Humphries, M., & Byard, R. W. (2024). Seasonal variation in cutaneous seat belt markings in fatal vehicle crashes. Australian Journal of Forensic Sciences, 56(1), 61-64.
2024 Stephenson, L., van den Heuvel, C., Humphries, M., Scott, T., & Byard, R. W. (2024). Increased incidence of mixed drug toxicity deaths involving tapentadol - A forensic study. Medicine Science and the Law, 64(2), 113-120.
Scopus1 Europe PMC22024 Stephenson, L., Van Den Heuvel, C., Humphries, M., Nash, C., & Byard, R. W. (2024). Features of fatal pesticide ingestion in South Australia. Medicine, Science and the Law, 64(4), 259-282.
Scopus1 Europe PMC12024 Stephenson, L., Van Den Heuvel, C., Humphries, M., & Byard, R. W. (2024). Prescribed and Diverted Methadone Toxicity in South Australia: An Update. American Journal of Forensic Medicine and Pathology, 45(2), 124-129.
2024 Stephenson, L., Tiemensma, M., Van Den Heuvel, C., & Byard, R. W. (2024). The spectrum of presentations of unintentional carbon monoxide poisoning. Medicine, Science and the Law, 64(4), 310-318.
2023 O’Donovan, S., van den Heuvel, C., Baldock, M., & Byard, R. W. (2023). An overview of suicides related to motor vehicles. Medicine, Science and the Law, 63(2), 151-158.
Scopus22023 Stephenson, L., Van Den Heuvel, C., & Byard, R. W. (2023). Socioeconomic and psychosocial determinants of substance misuse – a national perspective. Forensic Science, Medicine, and Pathology, 10 pages.
Scopus3 Europe PMC12023 O’Donovan, S., van den Heuvel, C., Baldock, M., Humphries, M. A., & Byard, R. W. (2023). Seat belt injuries and external markings at autopsy in cases of lethal vehicle crashes. Medicine, Science and the Law, 63(3), 195-202.
Europe PMC12023 Chandler, Z., van den Heuvel, C., Baldock, M., James, S., & Byard, R. W. (2023). The effect of age on injury patterns in pedestrian deaths. Medicine, Science and the Law, 63(4), 287-291.
Scopus1 Europe PMC12022 O'Donovan, S., Lewis, D., Van Den Heuvel, C., Baldock, M., Humphries, M. A., & Byard, R. W. (2022). Methamphetamine and alcohol detection in vehicle-driver fatalities in South Australia: A 10-year survey (2008-2018).. J Forensic Sci, 67(1), 257-264.
Scopus4 WoS32022 Hodgetts, S. I., Lovett, S. J., Baron-Heeris, D., Fogliani, A., Sturm, M., Van Den Heuvel, C., & Harvey, A. R. (2022). Effects of amyloid precursor protein peptide APP96-110, alone or with human mesenchymal stromal cells, on recovery after spinal cord injury. Neural Regeneration Research, 17(6), 1376-1386.
Scopus2 WoS2 Europe PMC12022 Rivers-Kennedy, A. D., Byard, R. W., Van Den Heuvel, C., Quill, R., & Langlois, N. E. I. (2022). Investigating the Source of Fatal Pulmonary Thromboembolism in a Coronial Postmortem Population.. Am J Forensic Med Pathol, 43(2), 1-4.
Scopus12022 Stephenson, L., Wills, S., Van Den Heuvel, C., Humphries, M., & Byard, R. W. (2022). Increasing use of sodium nitrite in suicides-an emerging trend.. Forensic Sci Med Pathol, 18(3), 311-318.
Scopus19 WoS7 Europe PMC102022 O'Donovan, S., Humphries, M., Van Den Heuvel, C., Baldock, M., & Byard, R. W. (2022). Cardiac disease and driver fatality.. Forensic Sci Med Pathol, 18(3), 329-332.
Scopus1 WoS1 Europe PMC12022 O'Donovan, S., Van Den Heuvel, C., Baldock, M., Humphries, M. A., & Byard, R. W. (2022). Fatal blunt chest trauma: an evaluation of rib fracture patterns and age.. International journal of legal medicine, 136(5), 1351-1357.
Scopus6 WoS3 Europe PMC32022 O'Donovan, S., van den Heuvel, C., Baldock, M., & Byard, R. W. (2022). Causes of fatalities in motor vehicle occupants: an overview.. Forensic science, medicine, and pathology, 18(4), 511-515.
Scopus1 Europe PMC12022 Stephenson, L., Van Den Heuvel, C., Humphries, M., & Byard, R. W. (2022). Characteristics of fatal insulin overdoses. Forensic Science, Medicine and Pathology, 18(4), 429-441.
Scopus8 WoS3 Europe PMC62022 Stephenson, L., Grabowski, M., Van Den Heuvel, C., Humphries, M., & Byard, R. W. (2022). Success of Low Aromatic Fuel in Preventing Gasoline Sniffing Deaths.. The American journal of forensic medicine and pathology, 43(4), 354-358.
Scopus1 WoS1 Europe PMC12022 Lewis, D., van den Heuvel, C., Kenneally, M., & Byard, R. W. (2022). Methamphetamine use and the risk of diabetic ketoacidosis. Medicine, Science and the Law, 62(1), 39-42.
Scopus5 WoS2 Europe PMC22021 O'Donovan, S., Van Den Heuvel, C., Baldock, M., & Byard, R. W. (2021). Upper and lower limb amputations in vehicle-related fatalities. Journal of Forensic and Legal Medicine, 82, 1-3.
Scopus1 Europe PMC12021 Lewis, D., Kenneally, M., Van Den Heuvel, C., & Byard, R. W. (2021). Methamphetamine deaths: Changing trends and diagnostic issues. Medicine, Science and the Law, 61(2), 1-8.
Scopus17 WoS9 Europe PMC82021 O'Donovan, S., Langlois, N. E., Heuvel, C. V. D., & Byard, R. W. (2021). Lethal mechanisms in cases of inverted suspension from the lap component of seat belts.. Med Sci Law, 61(3), 227-231.
Scopus2 WoS2 Europe PMC22021 Lewis, D., Kenneally, M., Van Den Heuvel, C., & Byard, R. W. (2021). Increasing age and methamphetamine use. Journal of Forensic and Legal Medicine, 80, 1-3.
Scopus6 WoS5 Europe PMC22021 Stephenson, L., Kenneally, M., van den Heuvel, C., Humphries, M., Stockham, P., & Byard, R. W. (2021). Recent trends in barbiturate detection in medicolegal deaths. Legal Medicine, 53, 1-5.
Scopus2 WoS2 Europe PMC32020 O'Donovan, S., Van Den Heuvel, C., Baldock, M., & Byard, R. W. (2020). Obesity and age as factors in leg amputations in fatal motorcycle crashes.. Medicine, science, and the law, 60(1), 26-29.
Scopus2 WoS1 Europe PMC12020 O'Donovan, S., Van Den Heuvel, C., Baldock, M., & Byard, R. W. (2020). Injuries, death and vehicle airbag deployment.. Med Sci Law, 60(2), 25802419892392.
Scopus10 WoS1 Europe PMC22020 Stephenson, L., van den Heuvel, C., & Byard, R. W. (2020). Weighted drownings - An example of augmentation or enhancement of a suicide method. Journal of Forensic and Legal Medicine, 70, 3 pages.
Scopus9 WoS42020 O'Donovan, S., Van Den Heuvel, C., Baldock, M., & Byard, R. W. (2020). Childhood cycling fatalities in South Australia before and after the introduction of helmet legislation.. Med Sci Law, 60(3), 196-199.
Scopus4 WoS22020 Stephenson, L., Byard, R. W., van den Heuvel, C., & Peden, A. E. (2020). Fatal drowning among tourists and recently arrived individuals from overseas at South Australian Metropolitan beaches. Australian Journal of Forensic Sciences, 53(5), 1-8.
Scopus3 WoS52020 Stephenson, L., Stockham, P., van den Heuvel, C., & Byard, R. W. (2020). Characteristics of drowning deaths in an inner city river. Legal Medicine, 47, 3 pages.
Scopus8 WoS3 Europe PMC22019 Stephenson, L., Van den Heuvel, C., & Byard, R. W. (2019). The persistent problem of drowning - A difficult diagnosis with inconclusive tests. Journal of Forensic and Legal Medicine, 66, 79-85.
Scopus40 WoS25 Europe PMC62018 Pilla, M., van den Heuvel, C., Musgrave, I., & Byard, R. W. (2018). Increasing incidence of nonlethal inflicted injuries in paediatric homicides: a 45-year study. Journal of Forensic and Legal Medicine, 59, 4-7.
Scopus2 WoS12018 O Donovan, S., van den Huevel, C., Baldock, M., & Byard, R. W. (2018). Factors involved in the assessment of paediatric traffic injuries and deaths. Medicine, Science and the Law, 58(4), 210-215.
Scopus17 WoS11 Europe PMC52018 Byard, R. W., O'Donovan, S., van den Huevel, C., & Baldock, M. (2018). Familial Vehicular Murder-Suicide. Journal of Forensic Sciences, 63(4), 1307-1308.
Scopus4 WoS3 Europe PMC12018 Plummer, S., Corrigan, F., Thornton, E., Woenig, J., Vink, R., Cappai, R., & Den Heuvel, C. (2018). The amyloid precursor protein derivative, APP96-110, is efficacious following intravenous administration after traumatic brain injury. PLoS ONE, 13(1), e0190449-1-e0190449-16.
Scopus16 WoS14 Europe PMC62018 Spinelli, J., Byard, R. W., Van Den Heuvel, C., & Collins-Praino, L. E. (2018). Medullary Astrogliosis in Sudden Infant Death Syndrome Varies With Sleeping Environment: Evidence for Different Mechanisms of Death in Alone Versus Co-sleepers?. Journal of child neurology, 33(4), 269-274.
Scopus12 WoS8 Europe PMC32017 Spinelli, J., Collins-Praino, L., Van Den Heuvel, C., & Byard, R. (2017). Evolution and significance of the triple risk model in sudden infant death syndrome. Journal of Paediatrics and Child Health, 53(2), 112-115.
Scopus24 WoS17 Europe PMC152017 Pearce, A., Lockwood, C., van den Heuvel, C., & Pearce, J. (2017). The use of therapeutic magnesium for neuroprotection during global cerebral ischemia associated with cardiac arrest and cardiac surgery in adults: a systematic review. JBI Database of Systematic Reviews and Implementation Reports, 15(1), 86-118.
Scopus12 Europe PMC82017 Austin, A., van den Heuvel, C., & Byard, R. (2017). Differences in local and national database recordings of deaths from suicide. Forensic Science, Medicine, and Pathology, 13(4), 403-408.
Scopus20 WoS14 Europe PMC42017 Finnie, G., Gunnarsson, R., Manavis, J., Blumbergs, P., Mander, K., Edwards, S., . . . Finnie, J. (2017). Characterization of an 'amyloid only' transgenic (B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax) mouse model of Alzheimer's disease. Journal of Comparative Pathology, 156(4), 389-399.
Scopus7 WoS6 Europe PMC62016 Plummer, S., Van Den Heuvel, C., Thornton, E., Corrigan, F., & Cappai, R. (2016). The neuroprotective properties of the amyloid precursor protein following traumatic brain injury. Aging and Disease, 7(2), 163-179.
Scopus79 WoS72 Europe PMC662015 Pearce, A., Lockwood, C., & Van Den Heuvel, C. (2015). The use of therapeutic magnesium for neuroprotection during global cerebral ischemia associated with cardiac arrest and cardiac bypass surgery in adults: a systematic review protocol. JBI database of systematic reviews and implementation reports, 13(4), 3-13.
Scopus9 Europe PMC22014 Giacci, M., Wheeler, L., Lovett, S., Dishington, E., Majda, B., Bartlett, C., . . . Fitzgerald, M. (2014). Differential effects of 670 and 830 nm red near infrared irradiation therapy: a comparative study of optic nerve injury, retinal degeneration, traumatic brain and spinal cord injury. PLoS One, 9(8), e104565-1-e104565-15.
Scopus41 WoS29 Europe PMC192014 Corrigan, F., Thornton, E., Roisman, L., Leonard, A., Vink, R., Blumbergs, P., . . . Cappai, R. (2014). The neuroprotective activity of the amyloid precursor protein against traumatic brain injury is mediated via the heparin binding site in residues 96-110. Journal of Neurochemistry, 128(1), 196-204.
Scopus46 WoS43 Europe PMC342014 Austin, A., Van Den Heuvel, C., & Byard, R. (2014). Body mass index and suicide. American Journal of Forensic Medicine and Pathology, 35(2), 145-147.
Scopus12 WoS8 Europe PMC52014 Austin, A., van den Heuvel, C., & Byard, R. (2014). Prison Suicides in South Australia: 1996-2010. Journal of Forensic Sciences, 59(5), 1260-1262.
Scopus25 WoS14 Europe PMC72013 Fitzgerald, M., Hodgetts, S., Van Den Heuvel, C., Natoli, R., Hart, N., Valter, K., . . . Dunlop, S. (2013). Red/near-infrared irradiation therapy for treatment of central nervous system injuries and disorders. Reviews in the Neurosciences, 24(2), 205-226.
Scopus71 WoS57 Europe PMC402013 Austin, A., Van Den Heuvel, C., & Byard, R. (2013). Suicide and fatal single occupant motor vehicle collisions. Australian Journal of Forensic Sciences, 45(1), 43-48.
Scopus10 WoS62013 Austin, A., Van Den Heuvel, C., & Byard, R. (2013). Physician suicide. Journal of Forensic Sciences, 58(SUPPL. 1), S91-S93.
Scopus19 WoS17 Europe PMC82012 Austin, A., Van Den Heuvel, C., Heath, K., Gilbert, J., & Byard, R. (2012). Recent firing range suicides in South Australia. Journal of Forensic Sciences, 57(6), 1495-1496.
Scopus3 WoS2 Europe PMC22012 Barry, C., Van Den Heuvel, C., Helps, S., & Vink, R. (2012). Cushing's mechanism maintains cerebral perfusion pressure in experimental subarachnoid haemorrhage. Neuroscience Letters, 529(1), 92-96.
Scopus1 WoS1 Europe PMC12012 Corrigan, F., Vink, R., Blumbergs, P., Masters, C., Cappai, R., & Van Den Heuvel, C. (2012). sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury. Journal of Neurochemistry, 122(1), 208-220.
Scopus66 WoS62 Europe PMC472012 Corrigan, F., Leonard, A., Ghabriel, M., Van Den Heuvel, C., & Vink, R. (2012). A Substance P Antagonist Improves Outcome in Female Sprague Dawley Rats Following Diffuse Traumatic Brain Injury. CNS Neuroscience & Therapeutics, 18(6), 513-515.
Scopus24 WoS21 Europe PMC122012 Corrigan, F., Vink, R., Blumbergs, P., Masters, C., Cappai, R., & Van Den Heuvel, C. (2012). Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury. Brain Research, 1451, 87-99.
Scopus35 WoS32 Europe PMC262012 Corrigan, F., Vink, R., Blumbergs, P., Masters, C., Cappai, R., & Van Den Heuvel, C. (2012). Evaluation of the effects of treatment with sAPPα on functional and histological outcome following controlled cortical impact injury in mice. Neuroscience Letters, 515(1), 50-54.
Scopus17 WoS17 Europe PMC132011 Austin, A., Van Den Heuvel, C., & Byard, R. (2011). Cluster hanging suicides in the young in South Australia. Journal of Forensic Sciences, 56(6), 1528-1530.
Scopus25 WoS18 Europe PMC122011 Gabrielian, L., Willshire, L., Helps, S., Van Den Heuvel, C., Mathias, J., & Vink, R. (2011). Intracranial pressure changes following traumatic brain injury in rats: Lack of significant change in the absence of mass lesions or hypoxia. Journal of Neurotrauma, 28(10), 2103-2111.
Scopus24 WoS22 Europe PMC172011 Austin, A., Van Den Heuvel, C., & Byard, R. (2011). Causes of community suicides among indigenous South Australians. Journal of Forensic and Legal Medicine, 18(7), 299-301.
Scopus19 WoS15 Europe PMC72011 Corrigan, F., Pham, C., Vink, R., Blumbergs, P., Masters, C., Van Den Heuvel, C., & Cappai, R. (2011). The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains. Brain Research, 1378, 137-143.
Scopus65 WoS65 Europe PMC502011 Barry, C., Helps, S., Van Den Heuvel, C., & Vink, R. (2011). Characterizing the role of the neuropeptide substance P in experimental subarachnoid hemorrhage. Brain Research, 1389, 143-151.
Scopus22 WoS21 Europe PMC142011 Austin, A., Winskog, C., Van Den Heuvel, C., & Byard, R. (2011). Recent trends in suicides utilizing helium. Journal of Forensic Sciences, 56(3), 649-651.
Scopus65 WoS53 Europe PMC272011 Byard, R., Austin, A., & Van Den Heuvel, C. (2011). Characteristics of asphyxial deaths in adolescence. Journal of Forensic and Legal Medicine, 18(3), 107-109.
Scopus15 WoS10 Europe PMC42011 Austin, A., Van Den Heuvel, C., & Byard, R. (2011). Suicide in forensic practice - an Australian perspective. Australian Journal of Forensic Sciences, 43(1), 65-76.
Scopus26 WoS252010 Vink, R., & Van Den Heuvel, C. (2010). Substance P antagonists as a therapeutic approach to improving outcome following traumatic brain injury. Neurotherapeutics, 7(1), 74-80.
Scopus49 WoS38 Europe PMC302010 Cook, N., Vink, R., Helps, S., Manavis, J., & Van Den Heuvel, C. (2010). Transient receptor potential melastatin 2 expression is increased following experimental traumatic brain injury in rats. Journal of Molecular Neuroscience, 42(2), 192-199.
Scopus36 WoS28 Europe PMC202010 Cook, N., Kleinig, T., Van Den Heuvel, C., & Vink, R. (2010). Reference genes for normalising gene expression data in collagenase-induced rat intracerebral haemorrhage. BMC Molecular Biology, 11(1), 1-11.
Scopus18 WoS16 Europe PMC162010 Byard, R., Austin, A., & Van Den Heuvel, C. (2010). Suicide in Australia: Meta-analysis of rates and methods of suicide between 1988 and 2007. Medical Journal of Australia, 193(7), 432.
Scopus12 WoS2 Europe PMC22009 Cook, N., Van Den Heuvel, C., & Vink, R. (2009). Are the transient receptor potential melastatin (TRPM) channels important in magnesium homeostasis following traumatic brain injury?. Magnesium Research, 22(4), 225-234.
Scopus20 WoS14 Europe PMC42009 Vink, R., Cook, N., & Van Den Heuvel, C. (2009). Magnesium in acute and chronic brain injury: an update. Magnesium Research, 22(3), 158S-162S.
Scopus42 WoS34 Europe PMC162009 Cook, N., Vink, R., Donkin, J., & Van Den Heuvel, C. (2009). Validation of reference genes for normalization of real-time quantitative RT-PCR data in traumatic brain injury. Journal of Neuroscience Research, 87(1), 34-41.
Scopus44 WoS42 Europe PMC352007 Van Den Heuvel, C., Thornton, E., & Vink, R. (2007). Traumatic brain injury and Alzheimer's disease: a review. Progress in Brain Research, 161, 303-316.
Scopus185 WoS163 Europe PMC1212006 Thornton, E., Vink, R., Blumbergs, P., & Van Den Heuvel, C. (2006). Soluble amyloid precursor protein a reduces neuronal injury and improves functional outcome following diffuse traumatic brain injury in rats. Brain Research, 1094(1), 38-46.
Scopus151 WoS139 Europe PMC1192005 Yang, L., Jones, N., Blumbergs, P., Van Den Heuvel, C., Bradford, E., Manavis, J., . . . Ghabriel, M. (2005). Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat. Journal of Clinical Neuroscience, 12(3), 276-284.
Scopus128 WoS116 Europe PMC1012004 Turner, R., Van Den Heuvel, C., & Vink, R. (2004). Amiloride increases neuronal damage after traumatic brain injury in rats. Journal of the American College of Nutrition, 23(5), 534S-537S.
Scopus10 WoS11 Europe PMC62004 Turner, R., Da Silva, K., O'Connor, C., Van Den Heuvel, C., & Vink, R. (2004). Magnesium gluconate offers no more protection than magnesium sulphate following diffuse traumatic brain injury in rats. Journal of the American College of Nutrition, 23(5), 541S-544S.
Scopus17 WoS11 Europe PMC62004 Van Den Heuvel, C., Donkin, J., Finnie, J., Blumbergs, P., Kuchel, T., Koszyca, B., . . . Vink, R. (2004). Downregulation of amyloid precursor protein (APP) expression following post-traumatic cyclosporin-A administration. Journal of Neurotrauma, 21(11), 1562-1572.
Scopus28 WoS26 Europe PMC172004 Vink, R., & Van Den Heuvel, C. (2004). Recent advances in the development of multifactorial therapies for the treatment of traumatic brain injury. Expert Opinion on Investigational Drugs, 13(10), 1263-1274.
Scopus54 WoS48 Europe PMC322004 Van Den Heuvel, C., & Vink, R. (2004). The role of magnesium in traumatic brain injury. Clinical Calcium, 14(8), 9-14.
Scopus38 Europe PMC172001 Finnie, J., Van Den Heuvel, C., Gebski, V., Manavis, J., Summersides, G., & Blumbergs, P. (2001). Investigation of the effects of impacts to different regions of the lamb head. Journal of Comparative Pathology, 124(02-Mar), 159-164.
Scopus16 WoS14 Europe PMC122000 Van Den Heuvel, C., Finnie, J., Blumbergs, P., Manavis, J., Jones, N., Reilly, P., & Pereira, R. (2000). Upregulation of neuronal amyloid precursor protein (APP) and APP mRNA following magnesium sulphate (MgSO4) therapy in traumatic brain injury. Journal of Neurotrauma, 17(11), 1041-1053.
Scopus13 WoS12 Europe PMC72000 Van Den Heuvel, C., Blumbergs, P., Finnie, J., Manavis, J., Lewis, S., Jones, N., . . . Pereira, R. (2000). Upregulation of amyloid precursor protein and its mRNA in an experimental model of paediatric head injury. Journal of Clinical Neuroscience, 7(2), 140-145.
Scopus21 WoS20 Europe PMC171999 Finnie, J., Lewis, S., Manavis, J., Blumbergs, P., Van Den Heuvel, C., & Jones, N. (1999). Traumatic axonal injury in lambs: a model for paediatric axonal damage. Journal of Clinical Neuroscience, 6(1), 38-42.
Scopus12 WoS13 Europe PMC111999 Van Den Heuvel, C., Blumbergs, P., Finnie, J., Manavis, J., Jones, N., Reilly, P., & Pereira, R. (1999). Upregulation of amyloid precursor protein messenger RNA in response to traumatic brain injury: An ovine head impact model. Experimental Neurology, 159(2), 441-450.
Scopus109 WoS101 Europe PMC801998 Van Den Heuvel, C., Lewis, S., Wong, M., Manavis, J., Finnie, J., Blumbergs, P., . . . Reilly, P. (1998). Diffuse neuronal perikaryon amyloid precursor protein immunoreactivity in a focal head impact model. Acta Neurochirurgica: Supplement, 71(SUPPL. 71), 209-211.
Scopus23 WoS23 Europe PMC7 -
Book Chapters
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Conference Papers
Year Citation 2022 Stephenson, L., Van Den Heuvel, C., Humphries, M., & Byard, R. (2022). A profile of pesticide self-poisonings in South Australia over 20 years. In TOXICOLOGY COMMUNICATIONS Vol. 6 (pp. 115-116). TAYLOR & FRANCIS LTD. 2015 Inampudi, C., Jana, M., Ciccotosto, G., Plummer, S., Roberts, B., van den Heuvel, C., & Cappai, R. (2015). Identification of proteins interacting with amyloid precursor protein for neurotoxicity and neuroprotection. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 199). Cairns, AUSTRALIA: WILEY-BLACKWELL. 2011 Corrigan, F., Pham, C., Vink, R., Masters, C., Blumbergs, P., Cappai, R., & Van den Heuvel, C. (2011). SAPPALPHA RESCUES DEFICITS IN AMYLOID PRECURSOR PROTEIN KNOCKOUT MICE FOLLOWING TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROTRAUMA Vol. 28 (pp. A67). Shanghai, PEOPLES R CHINA: MARY ANN LIEBERT INC. 2011 Corrigan, F., Vink, R., Masters, C., Blumbergs, P., Cappai, R., & Van den Heuvel, C. (2011). CHARACTERISING THE EFFECTS OF AMYLOID PRECURSOR PROTEIN KNOCKOUT ON OUTCOME FOLLOWING TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROTRAUMA Vol. 28 (pp. A28). Shanghai, PEOPLES R CHINA: MARY ANN LIEBERT INC. 2011 Cappai, R., Corrigan, F., Pham, C. L., Vink, R., Masters, C. L., Blumbergs, P. C., & van den Heuvel, C. (2011). DEFINING THE NEUROPROTECTIVE ACTIVITY OF ENDOGENOUSLY EXPRESSED AMYLOID PRECURSOR PROTEIN IN TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROCHEMISTRY Vol. 118 (pp. 209). WILEY. 2009 Corrigan, F., Cappai, R., Vink, R., & Van Den Heuvel, C. (2009). DETERMINING THE NEUROPROTECTIVE PROPERTIES OF THE AMYLOID PRECURSOR PROTEIN <i>IN VIVO</i>. In JOURNAL OF NEUROTRAUMA Vol. 26 (pp. A95). Santa Barbara, CA: MARY ANN LIEBERT INC. 2009 Cook, N., Van Den Heuvel, C., & Vink, R. (2009). CHARACTERIZATION OF TRPM CHANNEL MESSENGER RNA LEVELS IN TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROTRAUMA Vol. 26 (pp. A73). Santa Barbara, CA: MARY ANN LIEBERT INC. 2004 Van Den Heuvel, C., Thornton, E., Blumbergs, P., Rodgers, K., & Vink, R. (2004). Neuroprotective effects of sAPPα administration following diffuse traumatic brain injury. In 7th International Neurotrauma Symposium, Adelaide, Australia, 12-16 September, 2004 (pp. 145-149). Bologna Italy: Medimond International Proceedings. -
Conference Items
Year Citation 2018 Cappai, R., Inampudi, C., Corrigan, F., Lam, L., Roberts, B., Thornton, E., . . . Van den Heuvel, C. (2018). DELINEATING THE NEUROPROTECTIVE ROLE OF THE AMYLOID PRECURSOR PROTEIN FAMILY IN TRAUMATIC BRAIN INJURY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Toronto, CANADA: MARY ANN LIEBERT, INC. 2017 Plummer, S. L., Thornton, E., Corrigan, F., Vink, R., Cappai, R., & Van den Heuvel, C. (2017). Evaluating the amyloid precursor protein derivative, APP96-110, as a novel therapeutic agent following traumatic brain injury. Poster session presented at the meeting of JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. Int Soc Cerebral Blood Flow & Metab, Berlin, GERMANY: SAGE PUBLICATIONS INC. 2016 Collins-Praino, L., Teng, J., Colton, H., Van den Heuvel, C., & Corrigan, F. (2016). INVESTIGATING THE COMPLEX RELATIONSHIP BETWEEN NEUROINFLAMMATION, NEURODEGENERATION AND LONG-TERM FUNCTIONAL OUTCOMES IN AN EXPERIMENTAL MODEL OF TRAUMATIC BRAIN INJURY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Cape Town, SOUTH AFRICA: MARY ANN LIEBERT, INC. 2014 McAteer, K., Corrigan, F., Thornton, E., van den Heuvel, C., & Vink, R. (2014). CHARACTERISATION OF A NOVEL MODEL OF CHRONIC TRAUMATIC ENCEPHALOPATHY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Budapest, HUNGARY: MARY ANN LIEBERT, INC. 2014 Plummer, S., Thornton, E., Corrigan, F., Vink, R., Cappai, R., & van den Heuvel, C. (2014). EVALUATING APP96-110, A PEPTIDE DERIVED FROM THE AMYLOID PRECURSOR PROTEIN, AS A NOVEL THERAPEUTIC AGENT AGAINST TRAUMATIC BRAIN INJURY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Budapest, HUNGARY: MARY ANN LIEBERT, INC. 2012 Cappai, R., Corrigan, F., Blumbergs, P., Vink, R., & van den Heuvel, C. (2012). Delineating The Neuroprotective Region Of The Amyloid Precursor Protein (APP) Following Traumatic Brain Injury. Poster session presented at the meeting of BRAIN INJURY. INFORMA HEALTHCARE. 2000 Van Den Heuvel, C., Finnie, J., Blumbergs, P., Manavis, J., Jones, N., Reilly, P., & Pereira, R. (2000). Upregulation of neuronal amyloid precursor protein (APP) and APP mRNA following magnesium sulphate (MgSO4) therapy in traumatic brain injury. Poster session presented at the meeting of Restorative Neurology and Neuroscience. Amsterdam, The Netherlands: IOS Press. 2000 Finnie, J., Van Den Heuvel, C., Blumbergs, P., Manavis, J., Jones, N., & Reilly, P. (2000). Axonal damage in a lamb model of paediatric traumatic head injury after different types of head impact. Poster session presented at the meeting of Restorative Neurology and Neuroscience. Amsterdam, The Netherlands: IOS Press.
Total Research Funding
2018 | NHMRC project grant $874,733.50. Preclinical evaluation of the novel therapeutic compound APP96-110 in an ovine model of traumatic brain injury. Chief investigators; (CIA) Frances Corrigan, (CIB) Sanjay Garg, (CIC) Robert Vink, (CID) Corinna Van Den Heuvel, (CIE) Renee Turner. |
2017 | NHMRC project grant $648,739. APLP2: a neuroprotective receptor for acute brain injury. Chief Investigators (CIA) Roberto Cappai, (CIB) Peter Crack, Associate investigator (AI) Corinna Van Den Heuvel. |
2016 |
The Brain Foundation. $21,000. Developing a neuroprotective agent against neurotrauma. Chief Investigator: Corinna Van Den Heuve |
2015 - 2016 | Neurotrauma Research Program. $131, 651. Assessing APP 96-110: A novel neuroprotective agent in traumatic SCI. Chief Investigators: Stuart Hodgetts, Alan Harvey, Corinna Van Den Heuvel. |
2014 | Neurosurgical Research Foundation: $54,500. Equipment Grant. Chief Investigator: Corinna Van Den Heuvel. |
2013 - 2015 | Co Chief investigator. NHMRC $451, 420. Elucidating the Neuroprotective Region of the Amyloid Precursor Protein (APP) Following Traumatic Brain Injury. Chief Investigators: Robert Vink, Corinna Van Den Heuvel, Peter Blumbergs. |
2013 | Chief investigator. Brain Foundation Palmer-Brown and Harvey Estates Brain Injury Award. Assessment of the Neuroprotective Properties of the amyloid precursor protein following brain injury. $27,650: 1 year award. |
2008 - 2010 | Co-chief investigator, Neurosurgical Research Foundation. Studying the role of the amyloid presursor protein (APP) in modulating neurotrauma. Van Den Heuvel C, Cappai R. |
2008 - 2010 | NHMRC Project Grant $570,000. Raised intracranial pressure after trauma: characterisation and development of pharmacological interventions. Vink R, Blumbergs PC, Van Den Heuvel C. 3 year award. |
2007 - present | Neurotrauma Research Program: $144,000. Optimisation of red/near-infrared light therapy for treatment of neurotrauma: a multi-centre collaborative approach. Chief Investigators: A/Prof Melinda Fitzgerald, A/Prof Nathan Hart, Prof Sarah Dunlop, Prof Jan Provis, Dr Riccardo Natoli, A/Prof Stuart Hodgetts, Prof Alan Harvey, Prof Robert Vink, A/Prof Corinna van den Heuvel. $30,000: 1 year award. |
2004 - 2005 | Chief Investigator, University of Adelaide Small Grant. Assessment of the potential neuroprotective effects of soluble amyloid precursor protein a (sAPPa) following traumatic brain injury. Van Den Heuvel C. $14,000: 1 year award |
2003 | Co-chief Investigator, University of Adelaide B1 Grant. Characterization of the amyloid precursor response following traumatic brain injury: neuroprotective or deleterious? Van Den Heuvel C, Vink R.$ 14,750: 1 year award. |
2002 | Co-Chief Investigator, Royal Adelaide Hospital Project Grant. Establishing optimal methods to restore magnesium homeostasis as a therapeutic intervention following diffuse traumatic brain injury. Vink R, Van Den Heuvel C. $15,000: 1 year award |
2001 | Chief Investigator, University of Adelaide B3 Grant. Does magnesium sulphate affect APP mRNA expression within 2 hours following traumatic brain injury. Van Den Heuvel C. $11,000: 1 year award |
2000 | Co-chief investigator, Neurosurgical Research Foundation Grant. Axonal injury following traumatic brain injury. Jones N, Blumbergs PC, Van Den Heuvel C. $15,000: 1 year award |
2000 | Co-Chief Investigator, Australian Research Council (ARC) Small Grant. Quantitation Of The APP mRNA Response To Traumatic Brain Injury Using Real Time Quantitative PCR. Van Den Heuvel C, Blumbergs, PC. $10,000: 1 Year Award |
Program Coordinator Bachelor of Health and Medical Sciences
Course Coordinator Pathol 3101 - Essentials of Pathology
Teaches into other courses within Bachelor of Nursing, MBBS and Bachelor of Health and Medical Sciences
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Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2020 - 2024 Principal Supervisor A retrospective analysis of pharmaceutical and non-pharmaceutical substance-related coronial deaths in South Australia over 20 years Doctor of Philosophy Doctorate Full Time Miss Lilli Grace Stephenson 2018 - 2022 Principal Supervisor An Assessment of the Factors Associated with Fatal Outcomes for Motor Vehicle Occupants in South Australia (1981-2020) Doctor of Philosophy Doctorate Full Time Miss Siobhan O'Donovan 2017 - 2018 Co-Supervisor The Effectiveness of Magnesium for Neuroprotection during Global Cerebral Ischemia Associated with Cardiac Arrest or Cardiac Surgery Master of Clinical Science Master Full Time Dr Anna Catherine Mauri Pearce 2014 - 2018 Principal Supervisor Investigating Amyloid Precursor Protein Derivatives As Novel Therapeutic Agents Following Traumatic Brain Injury Doctor of Philosophy Doctorate Full Time Dr Stephanie Lauren Plummer 2012 - 2015 Principal Supervisor Suicide in South Australia: specific features, trends and reasons for disparities in numbers Doctor of Philosophy Doctorate Full Time Amy Austin 2008 - 2013 Co-Supervisor Development of Novel Pharmacological Treatments for Intracranial Pressure Using Appropriate Experimental Models of Traumatic Brain injury Doctor of Philosophy Doctorate Full Time Mr Levon Gabrielian 2008 - 2011 Co-Supervisor The Role of the Amyloid Precursor Protein following Traumatic Brain Injury Doctor of Philosophy Doctorate Full Time APrf Frances Corrigan 2007 - 2011 Co-Supervisor Characterising the role of the neuropeptide substance P in experimental subarachnoid haemorrhage Doctor of Philosophy Doctorate Full Time Ms Christine Barry 2006 - 2010 Co-Supervisor Characterisation of Substance P and Transient Receptor Potential Melastatin Channel Messenger RNA and Protein Expression in Acute and Chronic Neurological Disorders Doctor of Philosophy Doctorate Full Time Dr Naomi Cook 2003 - 2006 Co-Supervisor The Effects of the Neuropeptide Substance P on Outcome Following Experimental Traumatic Brain Injury in Rats Doctor of Philosophy Doctorate Full Time Mr James Donkin
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