Dr Frances Corrigan

Associate Prof/Reader

School of Biomedicine

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

A/Prof Corrigan is a research active member of the Discipline of Anatomy and Pathology, School of Biomedicine at the University of Adelaide. After completion of her PhD in Dec 2011 investigating neuroprotective agents for traumatic brain injury she undertook local (UofA) postdoctoral training gaining research expertise in models of psychiatric disorders. She currently leads the Head Injury Group within the School of Biomedicine investigating both the short and long-term effects of traumatic brain injury, the role of exogenous factors such as sex and age and how to intervene to prevent long-term consequences.

My Research
Career
Publications
Grants and Funding
Supervision
Professional Activities
Contact

Research

I lead the Head Injury Group, which liaises closely with the Translational Neuropathology lab and CANDL . My research is primarily focused on the mechanisms whereby concussion or mild traumatic brain injury can lead to the development of neurodegeneration, with particular interest in the role of neuroinflammation. This research also aims to identify novel pharmacological agents to prevent the long-term consequences of concussion.

Current projects:

1) Mapping the spread of toxic tau following traumatic brain injury to develop new biomarkers to identify those at risk of later developing dementia.

2) Understanding the temporal profile of axonal injury following traumatic brain injury in order to develop new treatments

3) Investigating whether the neuroinflammatory response influenced by age at which a traumatic brain injury occurs? Can we target this process to optimise treatment strategy dependent on age at injury.

4) Developing novel pre-clinical models of traumatic brain injury that more closely replicate the clinical situation

Awards and Achievements

Date	Type	Title	Institution Name	Country	Amount
2020	Award	CNBP Collaboration Prize	University of Adelaide	Australia	3000
2017	Award	South Australia Tall Poppy	-	Australia	-
2012	Achievement	Fresh Science South Australian State Finalist	-	Australia	-
2012	Award	Student Travel Award, International Neurotrauma Society	-	-	-
2011	Award	Faculty of Health Sciences Travel Award, University of Adelaide	-	Australia	-
2011	Award	Student Travel Award, Australian Neuroscience Society Meeting	-	Australia	-
2010	Award	School of Medical Sciences Travel Award, University of Adelaide	-	Australia	-
2010	Award	Poster Prize- Faculty of Health Sciences Research Expo	University of Adelaide	Australia	-
2010	Award	Student Travel Award, Australian Neuroscience Society Meeting	-	Australia	-
2008	Scholarship	Australian Postgraduate Research Award	University of Adelaide	-	-

Journals

Year	Citation
2024	Guglietti, B., Mustafa, S., Corrigan, F., & Collins-Praino, L. E. (2024). Anatomical distribution of Fyn kinase in the human brain in Parkinson's disease. Parkinsonism and Related Disorders, 118, 5 pages. DOI
2023	Krieg, J. L., Leonard, A. V., Turner, R. J., & Corrigan, F. (2023). Identifying the Phenotypes of Diffuse Axonal Injury Following Traumatic Brain Injury. Brain Sciences, 13(11), 1607-1-1607-19. DOI
2023	Corrigan, F., Arulsamy, A., Shultz, S. R., Wright, D. K., & Collins-Praino, L. E. (2023). Initial Severity of Injury Has Little Effect on the Temporal Profile of Long-Term Deficits in Locomotion, Anxiety, and Cognitive Function after Diffuse Traumatic Brain Injury. Neurotrauma Reports, 4(1), 41-50. DOI Scopus1
2023	Corrigan, F., Wee, I. C., & Collins-Praino, L. E. (2023). Chronic motor performance following different traumatic brain injury severity—A systematic review. Frontiers in Neurology, 14, 47 pages. DOI Scopus4 Europe PMC3
2023	Sharkey, J. M., Quarrington, R. D., Krieg, J. L., Kaukas, L., Turner, R. J., Leonard, A., . . . Corrigan, F. (2023). Evaluating the effect of post-traumatic hypoxia on the development of axonal injury following traumatic brain injury in sheep. Brain Research, 1817, 1-16. DOI Scopus2 Europe PMC2
2023	Krieg, J. L., Leonard, A. V., Tuner, R. J., & Corrigan, F. (2023). Characterization of Traumatic Brain Injury in a Gyrencephalic Ferret Model Using the Novel Closed Head Injury Model of Engineered Rotational Acceleration (CHIMERA). Neurotrauma Reports, 4(1), 761-780. DOI Scopus2 Europe PMC1
2022	Vink, R., & Corrigan, F. (2022). Chronic traumatic encephalopathy: Genes load the gun and repeated concussion pulls the trigger. Neural Regeneration Research, 17(9), 1963-1964. DOI Scopus1
2021	Singhal, G., Morgan, J., Corrigan, F., Toben, C., Jawahar, M. C., Jaehne, E. J., . . . Baune, B. T. (2021). Short-term environmental enrichment is a stronger modulator of brain glial cells and cervical lymph node T cell subtypes than exercise or combined exercise and enrichment. Cellular and Molecular Neurobiology, 41(3), 469-486. DOI Scopus6 WoS6 Europe PMC4
2021	Kaukas, L., Holmes, J. L., Rahimi, F., Collins-Praino, L., & Corrigan, F. (2021). Injury during adolescence leads to sex-specific executive function deficits in adulthood in a pre-clinical model of mild traumatic brain injury.. Behav Brain Res, 402, 1-14. DOI Scopus6 WoS5 Europe PMC4
2021	Singhal, G., Jawahar, M. C., Morgan, J., Corrigan, F., Jaehne, E. J., Toben, C., . . . Baune, B. T. (2021). TNF signaling via TNF receptors does not mediate the effects of short-term exercise on cognition, anxiety and depressive-like behaviors in middle-aged mice. Behavioural Brain Research, 408, 113269-1-113269-9. DOI
2021	Kaukas, L., Krieg, J., Collins-Praino, L., & Corrigan, F. (2021). Effects of Remote Immune Activation on Performance in the 5-Choice Serial Reaction Time Task Following Mild Traumatic Brain Injury in Adolescence. Frontiers in Behavioral Neuroscience, 15, 1-10. DOI Scopus2 WoS2 Europe PMC2
2021	Corrigan, F., Cernak, I., McAteer, K., Hellewell, S. C., Rosenfeld, J. V., Turner, R. J., & Vink, R. (2021). NK1 antagonists attenuate tau phosphorylation after blast and repeated concussive injury. Scientific Reports, 11(1), 1-9. DOI Scopus11 WoS8 Europe PMC8
2021	Guglietti, B., Carr, L., Ellul, B., Mustafa, S., Corrigan, F., & Collins-Praino, L. E. (2021). Fyn kinase inhibition using AZD0530 improves recognition memory and reduces depressive-like behaviour in an experimental model of Parkinson’s disease. DOI
2021	Deng, I., Corrigan, F., Garg, S., Zhou, X. F., & Bobrovskaya, L. (2021). Further characterization of intrastriatal lipopolysaccharide model of parkinson’s disease in c57bl/6 mice. International Journal of Molecular Sciences, 22(14), 20 pages. DOI Scopus8 WoS6 Europe PMC4
2021	Guglietti, B., Sivasankar, S., Mustafa, S., Corrigan, F., & Collins-Praino, L. E. (2021). Fyn Kinase Activity and Its Role in Neurodegenerative Disease Pathology: a Potential Universal Target?. Mol Neurobiol, 58(11), 5986-6005. DOI Scopus21 WoS14 Europe PMC14
2020	Deng, I., Corrigan, F., Zhai, G., Zhou, X. -F., & Bobrovskaya, L. (2020). Lipopolysaccharide animal models of Parkinson's disease: Recent progress and relevance to clinical disease. Brain Behav Immun Health, 4, 1-12. DOI Scopus56 WoS42 Europe PMC28
2020	Shultz, S. R., McDonald, S. J., Corrigan, F., Semple, B. D., Salberg, S., Zamani, A., . . . Mychasiuk, R. (2020). The clinical relevance of behavior testing in animal models of traumatic brain injury. Journal of Neurotrauma, 37(22), 23811-2400. DOI Scopus35 WoS27 Europe PMC20
2020	Mohamed, A. Z., Corrigan, F., Collins-Praino, L. E., Plummer, S. L., Soni, N., & Nasrallah, F. A. (2020). Evaluating spatiotemporal microstructural alterations following diffuse traumatic brain injury. NeuroImage: Clinical, 25, 15 pages. DOI Scopus26 WoS18 Europe PMC17
2020	Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., . . . Baune, B. T. (2020). Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression. Behavioural Brain Research, 383(6), 112501-1-112501-16. DOI Scopus19 WoS15 Europe PMC12
2020	McDonald, S. J., Sharkey, J. M., Sun, M., Kaukas, L., Shultz, S. R., Turner, R., . . . Corrigan, F. (2020). Beyond the brain: peripheral interactions following traumatic brain injury. Journal of Neurotrauma, 37(5), 770-781. DOI Scopus70 WoS55 Europe PMC50
2020	Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., . . . Baune, B. T. (2020). Duration of environmental enrichment determines astrocyte number and cervical lymph node T lymphocyte proportions but not the microglial number in middle-aged C57BL/6 mice. Frontiers in Cellular Neuroscience, 14, 57-1-57-12. DOI Scopus9 WoS9 Europe PMC5
2019	Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., . . . Baune, B. T. (2019). The effects of short-term and long-term environmental enrichment on locomotion, mood-like behavior, cognition and hippocampal gene expression. Behavioural Brain Research, 368, 111917-1-111917-10. DOI Scopus23 WoS18 Europe PMC12
2019	Arulsamy, A., Corrigan, F., & Collins-Praino, L. E. (2019). Age, but not severity of injury, mediates decline in executive function: validation of the rodent touchscreen paradigm for preclinical models of traumatic brain injury. Behavioural Brain Research, 368, 1-14. DOI Scopus3 WoS2 Europe PMC3
2019	Morgan, J. A., Singhal, G., Corrigan, F., Jaehne, E. J., Jawahar, M. C., Breen, J., . . . Baune, B. T. (2019). Ceasing exercise induces depression-like, anxiety-like, and impaired cognitive-like behaviours and altered hippocampal gene expression. Brain Research Bulletin, 148, 118-130. DOI Scopus17 WoS17 Europe PMC11
2019	Arulsamy, A., Corrigan, F., & Collins-Praino, L. E. (2019). Cognitive and neuropsychiatric impairments vary as a function of injury severity at 12 months post-experimental diffuse traumatic brain injury: implications for dementia development. Behavioural Brain Research, 365, 66-76. DOI Scopus13 WoS10 Europe PMC6
2019	Singhal, G., Morgan, J., Jawahar, M. C., Corrigan, F., Jaehne, E. J., Toben, C., . . . Baune, B. T. (2019). Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression. Cognitive, Affective and Behavioral Neuroscience, 19(5), 1143-1169. DOI Scopus16 WoS14 Europe PMC11
2018	Collins-Praino, L. E., Gutschmidt, D., Sharkey, J., Arulsamy, A., & Corrigan, F. (2018). Temporal changes in tau phosphorylation and related kinase and phosphatases following two models of traumatic brain injury. Journal of Neuroinflammation and Neurodegenerative Disease, 2(1), 10007-1-10007-13.
2018	Morgan, J., Singhal, G., Corrigan, F., Jaehne, E., Jawahar, M., & Baune, B. (2018). Exercise related anxiety-like behaviours are mediated by TNF receptor signaling, but not depression-like behaviours. Brain Research, 1695, 10-17. DOI Scopus10 WoS10 Europe PMC5
2018	Morgan, J., Singhal, G., Corrigan, F., Jaehne, E., Jawahar, M., & Baune, B. (2018). TNF signalling via the TNF receptors mediates the effects of exercise on cognition-like behaviours. Behavioural Brain Research, 353, 74-82. DOI Scopus15 WoS13 Europe PMC7
2018	Collins-Praino, L., & Corrigan, F. (2018). Cerebrovascular contribution to dementia development after traumatic brain injury: promises and problems. Annals of translational medicine, 6(Suppl. 1), S58-1-S58-5. DOI WoS1
2018	Collins-Praino, L., Arulsamy, A., Katharesan, V., & Corrigan, F. (2018). The effect of an acute systemic inflammatory insult on the chronic effects of a single mild traumatic brain injury. Behavioural Brain Research, 336, 22-31. DOI Scopus35 WoS34 Europe PMC20
2018	Morgan, J., Singhal, G., Corrigan, F., Jaehne, E., Jawahar, M., & Baune, B. (2018). The effects of aerobic exercise on depression-like, anxiety-like, and cognition-like behaviours over the healthy adult lifespan of C57BL/6 mice. Behavioural Brain Research, 337, 193-203. DOI Scopus57 WoS50 Europe PMC24
2018	Plummer, S., Corrigan, F., Thornton, E., Woenig, J., Vink, R., Cappai, R., & Den Heuvel, C. (2018). The amyloid precursor protein derivative, APP96-110, is efficacious following intravenous administration after traumatic brain injury. PLoS ONE, 13(1), e0190449-1-e0190449-16. DOI Scopus16 WoS14 Europe PMC6
2018	Morgan, J., Olagunju, A., Corrigan, F., & Baune, B. (2018). Does ceasing exercise induce depressive symptoms? A systematic review of experimental trials including immunological and neurogenic markers. Journal of Affective Disorders, 234, 180-192. DOI Scopus26 WoS15 Europe PMC7
2018	Arulsamy, A., Teng, J., Colton, H., Corrigan, F., & Collins-Praino, L. (2018). Evaluation of early chronic functional outcomes and their relationship to pre-frontal cortex and hippocampal pathology following moderate-severe traumatic brain injury. Behavioural Brain Research, 348, 127-138. DOI Scopus19 WoS18 Europe PMC7
2017	McAteer, K. M., Turner, R. J., & Corrigan, F. (2017). Animal models of chronic traumatic encephalopathy. Concussion (London, England), 2(2), 1-18. DOI Europe PMC8
2017	Corrigan, F., Arulsamy, A., Teng, J., & Collins-Praino, L. (2017). Pumping the Brakes: Neurotrophic Factors for the Prevention of Cognitive Impairment and Dementia after Traumatic Brain Injury. Journal of Neurotrauma, 34(5), 971-986. DOI Scopus16 WoS13 Europe PMC6
2017	Collins-Praino, L., & Corrigan, F. (2017). Does neuroinflammation drive the relationship between tau hyperphosphorylation and dementia development following traumatic brain injury?. Brain, Behavior, and Immunity, 60, 369-382. DOI Scopus64 WoS57 Europe PMC40
2017	Corrigan, F., Arulsamy, A., Collins-Praino, L., Holmes, J., & Vink, R. (2017). Toll like receptor 4 activation can be either detrimental or beneficial following mild repetitive traumatic brain injury depending on timing of activation. Brain, Behavior, and Immunity, 64(3), 124-139. DOI Scopus35 WoS32 Europe PMC17
2016	Plummer, S., Van Den Heuvel, C., Thornton, E., Corrigan, F., & Cappai, R. (2016). The neuroprotective properties of the amyloid precursor protein following traumatic brain injury. Aging and Disease, 7(2), 163-179. DOI Scopus76 WoS72 Europe PMC65
2016	McAteer, K., Corrigan, F., Thornton, E., Turner, R., & Vink, R. (2016). Short and long term behavioral and pathological changes in a novel rodent model of repetitive mild traumatic brain Injury. PLOS ONE, 11(8), e0160220-1-e0160220-18. DOI Scopus61 WoS56 Europe PMC41
2016	Corrigan, F., Vink, R., & Turner, R. J. (2016). Inflammation in acute CNS injury: a focus on the role of substance P. British Journal of Pharmacology, 173(4), 703-715. DOI Scopus53 WoS42 Europe PMC33
2016	Corrigan, F., Mander, K., Leonard, A., & Vink, R. (2016). Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation. Journal of Neuroinflammation, 13(1), 264-1-264-12. DOI Scopus220 WoS198 Europe PMC134
2015	Camara, M., Corrigan, F., Jaehne, E., Jawahar, M., Anscomb, H., & Baune, B. (2015). Tumor necrosis factor alpha and its receptors in behaviour and neurobiology of adult mice, in the absence of an immune challenge. Behavioural Brain Research, 290, 51-60. DOI Scopus15 WoS15 Europe PMC8
2015	Morgan, J., Corrigan, F., & Baune, B. (2015). Effects of physical exercise on central nervous system functions: a review of brain region specific adaptations. Journal of Molecular Psychiatry, 3(1), 3-1-3-13. DOI Europe PMC45
2015	Jaehne, E., Corrigan, F., Toben, C., Jawahar, M., & Baune, B. (2015). The effect of the antipsychotic drug quetiapine and its metabolite norquetiapine on acute inflammation, memory and anhedonia. Pharmacology, Biochemistry, and Behavior, 135, 136-144. DOI Scopus32 WoS29 Europe PMC22
2015	Camara, M., Corrigan, F., Jaehne, E., Jawahar, M., Anscomb, H., & Baune, B. (2015). Effects of centrally administered etanercept on behavior, microglia, and astrocytes in mice following a peripheral immune challenge. Neuropsychopharmacology, 40(2), 502-512. DOI Scopus65 WoS60 Europe PMC38
2015	Corrigan, F., Wu, Y., Tuke, J., Coller, J., Rice, K., Diener, K., . . . Hutchinson, M. (2015). Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling. Brain, Behavior, and Immunity, 45, 245-252. DOI Scopus20 WoS17 Europe PMC18
2014	Singhal, G., Jaehne, E., Corrigan, F., Toben, C., & Baune, B. (2014). Inflammasomes in neuroinflammation and changes in brain function: a focused review. Frontiers in Neuroscience, 8(SEP), 315-1-315-22. DOI Scopus290 WoS244 Europe PMC160
2014	Thornton, E., Hassall, M., Corrigan, F., & Vink, R. (2014). The NK1 receptor antagonist N-acetyl-l-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model. Parkinsonism and Related Disorders, 20(5), 508-513. DOI Scopus23 WoS21 Europe PMC18
2014	Singhal, G., Jaehne, E., Corrigan, F., & Baune, B. (2014). Cellular and molecular mechanisms of immunomodulation in the brain through environmental enrichment. Frontiers in Cellular Neuroscience, 8(1 APR), 97-1-97-29. DOI Scopus85 WoS78 Europe PMC48
2014	Stuart, M., Corrigan, F., & Baune, B. (2014). Knockout of CXCR5 increases the population of immature neural cells and decreases proliferation in the hippocampal dentate gyrus. Journal of Neuroinflammation, 11(1), 31-1-31-9. DOI Scopus23 WoS23 Europe PMC16
2014	Harrison, E., Jaehne, E., Jawahar, M., Corrigan, F., & Baune, B. (2014). Maternal separation modifies behavioural and neuroendocrine responses to stress in CCR7 deficient mice. Behavioural Brain Research, 263, 169-175. DOI Scopus23 WoS21 Europe PMC15
2014	Corrigan, F., Thornton, E., Roisman, L., Leonard, A., Vink, R., Blumbergs, P., . . . Cappai, R. (2014). The neuroprotective activity of the amyloid precursor protein against traumatic brain injury is mediated via the heparin binding site in residues 96-110. Journal of Neurochemistry, 128(1), 196-204. DOI Scopus46 WoS43 Europe PMC34
2014	Grundy, T., Toben, C., Jaehne, E., Corrigan, F., & Baune, B. (2014). Long-term omega-3 supplementation modulates behavior, hippocampal fatty acid concentration, neuronal progenitor proliferation and central TNF-alpha expression in 7 month old unchallenged mice. Frontiers in Cellular Neuroscience, 8, 399-1-399-13. DOI WoS13 Europe PMC13
2013	Camara, M., Corrigan, F., Jaehne, E., Jawahar, M., Anscomb, H., Koerner, H., & Baune, B. (2013). TNF-α and its receptors modulate complex behaviours and neurotrophins in transgenic mice. PsychoNeuroendocrinology, 38(12), 3102-3114. DOI Scopus64 WoS57 Europe PMC43
2012	Corrigan, F., Vink, R., Blumbergs, P., Masters, C., Cappai, R., & Van Den Heuvel, C. (2012). sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury. Journal of Neurochemistry, 122(1), 208-220. DOI Scopus65 WoS62 Europe PMC47
2012	Corrigan, F., & Hutchinson, M. (2012). Are the effects of alcohol on the CNS influenced by Toll-like receptor signaling?. Expert Review of Clinical Immunology, 8(3), 201-203. DOI Scopus6 WoS4 Europe PMC3
2012	Corrigan, F., Leonard, A., Ghabriel, M., Van Den Heuvel, C., & Vink, R. (2012). A Substance P Antagonist Improves Outcome in Female Sprague Dawley Rats Following Diffuse Traumatic Brain Injury. CNS Neuroscience & Therapeutics, 18(6), 513-515. DOI Scopus24 WoS21 Europe PMC12
2012	Corrigan, F., Vink, R., Blumbergs, P., Masters, C., Cappai, R., & Van Den Heuvel, C. (2012). Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury. Brain Research, 1451, 87-99. DOI Scopus34 WoS32 Europe PMC25
2012	Barry, C., Turner, R., Corrigan, F., & Vink, R. (2012). New therapeutic approaches to subarachnoid hemorrhage. Expert Opinion on Investigational Drugs, 21(6), 845-859. DOI Scopus21 WoS13 Europe PMC10
2012	Corrigan, F., Vink, R., Blumbergs, P., Masters, C., Cappai, R., & Van Den Heuvel, C. (2012). Evaluation of the effects of treatment with sAPPα on functional and histological outcome following controlled cortical impact injury in mice. Neuroscience Letters, 515(1), 50-54. DOI Scopus17 WoS17 Europe PMC13
2011	Corrigan, F., Pham, C., Vink, R., Blumbergs, P., Masters, C., Van Den Heuvel, C., & Cappai, R. (2011). The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains. Brain Research, 1378, 137-143. DOI Scopus63 WoS65 Europe PMC50
2011	Corrigan, F., Ziebell, J., & Vink, R. (2011). Models of rodent cortical traumatic brain injury. Neuromethods, 62, 193-209. DOI Scopus3
-	Wee, I. C., Arulsamy, A., Corrigan, F., & Collins-Praino, L. (n.d.). Long-Term Impact of Diffuse Traumatic Brain Injury on Neuroinflammation and Catecholaminergic Signaling: Potential Relevance for Parkinson’s Disease Risk. Molecules, 29(7), 1470. DOI

Book Chapters

Year	Citation
2018	Holmes, J., Corrigan, F., & Hutchinson, M. R. (2018). Neuroimmunopharmacology at the Interface of Inflammation and Pharmacology Relevant to Depression. In B. T. Baune (Ed.), Inflammation and Immunity in Depression Basic Science and Clinical Applications (pp. 223-240). United Kingdom: Academic Press. DOI
2012	Turner, R., Corrigan, F., & Vink, R. (2012). Magnesium in acute brain injury. In Y. Li, & J. Zhang (Eds.), Metal Ion in Stroke (1 ed., pp. 445-460). United States: Springer. DOI Scopus1
2011	Cook, N., Corrigan, F., & Van Den Heuvel, C. (2011). The role of magnesium in CNS injury. In R. Vink, & M. Nechifor (Eds.), Magnesium in the Central Nervous System (pp. 167-179). Australia: University of Adelaide Press. DOI Scopus8

Conference Papers

Year	Citation
2023	Krieg, J., Leonard, A., Turner, R., & Corrigan, F. (2023). EVALUATION OF DIFFUSE AXONAL INJURY IN PAEDIATRIC AND ADULT NOVEL GYRENCEPHALIC FERRET MODELS OF TBI. In JOURNAL OF NEUROTRAUMA Vol. 40 (pp. A55). TX, Austin: MARY ANN LIEBERT, INC.
2015	Plummer, S., Thornton, E., Corrigan, F., Vink, R., Cappai, R., & Heuvel, C. V. D. (2015). Investigation of the amyloid precursor protein derivative APP96-110 as a novel therapeutic agent following traumatic brain injury. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 145). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2015	McAteer, K., Corrigan, F., Thornton, E., Turner, R., & Vink, R. (2015). Short and long term behavioral and pathological changes in a novel rodent model of repetitive mild traumatic brain injury. In Abstracts of the 25th Biennial Meeting of the International Society for Neurochemistry jointly with the 13th Meeting of the Asian‐Pacific Society for Neurochemistry in conjunction with the 35th Meeting of the Australasian Neuroscience Society, as published in Vol. 134 (pp. 340-341). Cairns, AUSTRALIA: Wiley-Blackwell. DOI
2015	Corrigan, F., McAteer, K., & Vink, R. (2015). Toll-like receptor 4 activation exacerbates injury following repetitive mild traumatic brain injury. In JOURNAL OF NEUROCHEMISTRY Vol. 134 (pp. 196-197). Cairns, AUSTRALIA: WILEY-BLACKWELL.
2011	Corrigan, F., Pham, C., Vink, R., Masters, C., Blumbergs, P., Cappai, R., & Van den Heuvel, C. (2011). SAPPALPHA RESCUES DEFICITS IN AMYLOID PRECURSOR PROTEIN KNOCKOUT MICE FOLLOWING TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROTRAUMA Vol. 28 (pp. A67). Shanghai, PEOPLES R CHINA: MARY ANN LIEBERT INC.
2011	Corrigan, F., Vink, R., Masters, C., Blumbergs, P., Cappai, R., & Van den Heuvel, C. (2011). CHARACTERISING THE EFFECTS OF AMYLOID PRECURSOR PROTEIN KNOCKOUT ON OUTCOME FOLLOWING TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROTRAUMA Vol. 28 (pp. A28). Shanghai, PEOPLES R CHINA: MARY ANN LIEBERT INC.
2011	Cappai, R., Corrigan, F., Pham, C. L., Vink, R., Masters, C. L., Blumbergs, P. C., & van den Heuvel, C. (2011). DEFINING THE NEUROPROTECTIVE ACTIVITY OF ENDOGENOUSLY EXPRESSED AMYLOID PRECURSOR PROTEIN IN TRAUMATIC BRAIN INJURY. In JOURNAL OF NEUROCHEMISTRY Vol. 118 (pp. 209). WILEY.
2009	Corrigan, F., Cappai, R., Vink, R., & Van Den Heuvel, C. (2009). DETERMINING THE NEUROPROTECTIVE PROPERTIES OF THE AMYLOID PRECURSOR PROTEIN <i>IN VIVO</i>. In JOURNAL OF NEUROTRAUMA Vol. 26 (pp. A95). Santa Barbara, CA: MARY ANN LIEBERT INC.

Conference Items

Year	Citation
2019	Sharkey, J., Turner, R., Leonard, A., & Corrigan, F. (2019). INVESTIGATING THE PATTERN OF AXONAL INJURY FOLLOWING TRAUMATIC BRAIN INJURY OF VARYING INTENSITY IN A LARGE ANIMAL MODEL. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Pittsburgh, PA: MARY ANN LIEBERT, INC.
2019	Corrigan, F., Kaukas, L., Collins-Praino, L., & Holmes, J. (2019). EFFECT OF A MILD TRAUMATIC BRAIN INJURY DURING ADOLESCENCE ON EXECUTIVE FUNCTION IN ADULTHOOD. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Pittsburgh, PA: MARY ANN LIEBERT, INC.
2018	Cappai, R., Inampudi, C., Corrigan, F., Lam, L., Roberts, B., Thornton, E., . . . Van den Heuvel, C. (2018). DELINEATING THE NEUROPROTECTIVE ROLE OF THE AMYLOID PRECURSOR PROTEIN FAMILY IN TRAUMATIC BRAIN INJURY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Toronto, CANADA: MARY ANN LIEBERT, INC.
2017	Plummer, S. L., Thornton, E., Corrigan, F., Vink, R., Cappai, R., & Van den Heuvel, C. (2017). Evaluating the amyloid precursor protein derivative, APP96-110, as a novel therapeutic agent following traumatic brain injury. Poster session presented at the meeting of JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. Int Soc Cerebral Blood Flow & Metab, Berlin, GERMANY: SAGE PUBLICATIONS INC.
2016	Corrigan, F., & Vink, R. (2016). Toll like receptor 4 activation can be either detrimental or beneficial following mild repetitive traumatic brain injury depending on timing of activation. Poster session presented at the meeting of Abstracts of the 12th Symposium of the International Neurotrauma Society, as published in Journal of Neurotrauma. Cape Town, SOUTH AFRICA: Mary Ann Liebert. DOI
2016	Collins-Praino, L., Teng, J., Colton, H., Van den Heuvel, C., & Corrigan, F. (2016). INVESTIGATING THE COMPLEX RELATIONSHIP BETWEEN NEUROINFLAMMATION, NEURODEGENERATION AND LONG-TERM FUNCTIONAL OUTCOMES IN AN EXPERIMENTAL MODEL OF TRAUMATIC BRAIN INJURY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Cape Town, SOUTH AFRICA: MARY ANN LIEBERT, INC.
2015	Morgan, J. A., Corrigan, F., Jaehne, E., Jawahar, C., Singhal, G., & Baune, B. T. (2015). "Does exercise cessation induce depression in middle age?" (oral presentation). Poster session presented at the meeting of Florey International Postgraduate Research Conference.
2014	Morgan, J. A., Corrigan, F., Jaehne, E., & Baune, B. T. (2014). "Chronic physical exercise induced adaptations in the brain-stem and hypothalamus: A brief review of exercise effects on stress responses, the circadian clock, and energy balance metabolism.. Poster session presented at the meeting of The Society for Mental Health Research.
2014	Morgan, J. A., Corrigan, F., Jaehne, E., & Baune, B. T. (2014). "Exercise induced effects on anxiety, cognition, and depression in early adulthood and middle age". Poster session presented at the meeting of The Society for Mental Health Research.
2014	Morgan, J. A., Corrigan, F., Jaehne, E., & Baune, B. T. (2014). "Physical exercise impacts on cognitive and depression-like behaviours in C57BL/6 mice". Poster session presented at the meeting of Australasian Neurosciences Society 34th Annual Meeting.
2014	McAteer, K., Corrigan, F., Thornton, E., van den Heuvel, C., & Vink, R. (2014). CHARACTERISATION OF A NOVEL MODEL OF CHRONIC TRAUMATIC ENCEPHALOPATHY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Budapest, HUNGARY: MARY ANN LIEBERT, INC.
2014	Plummer, S., Thornton, E., Corrigan, F., Vink, R., Cappai, R., & van den Heuvel, C. (2014). EVALUATING APP96-110, A PEPTIDE DERIVED FROM THE AMYLOID PRECURSOR PROTEIN, AS A NOVEL THERAPEUTIC AGENT AGAINST TRAUMATIC BRAIN INJURY. Poster session presented at the meeting of JOURNAL OF NEUROTRAUMA. Budapest, HUNGARY: MARY ANN LIEBERT, INC.
2013	Morgan, J. A., Corrigan, F., Jaehne, E., & Baune, B. T. (2013). "Exercise neurobiology: A review of the effects of exercise on regions of the brain". Poster session presented at the meeting of The University of Adelaide Faculty of Health Sciences Postgraduate Research Conference.
2012	Cappai, R., Corrigan, F., Blumbergs, P., Vink, R., & van den Heuvel, C. (2012). Delineating The Neuroprotective Region Of The Amyloid Precursor Protein (APP) Following Traumatic Brain Injury. Poster session presented at the meeting of BRAIN INJURY. INFORMA HEALTHCARE.

Corrigan F, Turner R, Abou-Hamden A. Targeting inflammation to prevent brain swelling following paediatric head injury

2019-2020: 214,500, James and Diana Ramsey Foundation

Corrigan F, Nasrallah F, Collins-Praino LE, Developing imaging biomarkers that predict pre-frontal cortex deficits following

concussive insults in adolescence. 2019: 35,246, Neurosurgical Research Foundation

Corrigan F, Vink R, Turner RJ, Van Den Heuvel C, Cappai R, Preclinical evaluation of the novel therapeutic compound

APP96-110 in an ovine model of traumatic brain injury. 2018-2020: 874,744.50. NHMRC

Corrigan F, Collins-Praino LE, The role of alcohol in promoting the development of neurodegeneration following repetitive

mild traumatic brain injury 2018: 24 440, Neurosurgical Research Foundation

Leonard AV, Corrigan F, Collins-Praino LE, Spinal Cord Injury Research Program – Equipment funding. 2016: 30,000,

Neurosurgical Research Foundation

Corrigan F. The role of the SP-NK1 system in promoting the vulnerability to concussion in adolescence. 2017: $19,000

Neurosurgical Research Foundation

Corrigan, F. Investigating the effects of toll-like receptor 4 activation on outcome following repeated concussion 2016: 22,000

Neurosurgical Research Foundation

Corrigan, F: Role of alcohol induced changes in the gut microbiome promotes the development of depression via induction of

a systemic inflammatory response. 2015: $19,000. School of Medical Sciences, Kick-Start Funding, University of Adelaide

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2023	Principal Supervisor	Using a novel gyrencephalic model of pediatric injury to evaluate new therapeutics.	Doctor of Philosophy	Doctorate	Full Time	Mr Giuseppe Rinaldi
2023	Principal Supervisor	Utility of Rotational Thromboelastometry in Neurosurgical Management of Acute Severe Traumatic Brain Injury	Doctor of Philosophy	Doctorate	Part Time	Mr Abhiram Hiwase
2023	Principal Supervisor	Evaluation of novel therapeutics in a novel gyrencephalic model of traumatic brain injury	Doctor of Philosophy	Doctorate	Full Time	Mr Carl Llewelyn Hooper
2022	Co-Supervisor	Assessing olfactory system pathology and accelerated a-synuclein spread following Traumatic Brain Injury, and their role in the development of Parkinson's Disease pathology.	Doctor of Philosophy	Doctorate	Full Time	Ms Samantha Elizabeth Edwards
2022	Principal Supervisor	Characterising the role of cognitive dysfunction and spread of underlying tau pathology in the development of Alzheimer's disease following traumatic brain injury	Doctor of Philosophy	Doctorate	Full Time	Miss Eleanor Rose Bowley-Schubert
2021	Principal Supervisor	Preclinical evaluation of the novel therapeutic compound APP96-110 in a ferret model of traumatic brain injury.	Doctor of Philosophy	Doctorate	Full Time	Mr Justin Leigh Krieg
2021	Co-Supervisor	Evaluating the role of concomitant traumatic brain injury on the development of neuropathic pain following traumatic spinal cord injury	Doctor of Philosophy	Doctorate	Full Time	Miss Keziah Jane Skein

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2019 - 2024	Co-Supervisor	Exploring the Behavioural and Brain Basis of the Link Between Traumatic Brain Injury and Parkinson’s disease	Doctor of Philosophy	Doctorate	Full Time	Miss Ing Chee Wee
2019 - 2021	Co-Supervisor	Targeting Cognitive Impairment in Parkinson’s Disease: Novel Pharmacological and Non-Pharmacological Approaches	Doctor of Philosophy	Doctorate	Full Time	Miss Bianca Laura Guglietti
2017 - 2021	Co-Supervisor	Bridging the Gap in Clinical Translation: Optimising an Ovine Model of Traumatic Brain Injury	Doctor of Philosophy	Doctorate	Full Time	Miss Jessica May Sharkey
2016 - 2019	Co-Supervisor	From Trauma to Neurodegeneration: A One-Year Time Progression of Functional Impairments and its Associated Neuropathological Link Following Varied Severity of Experimental Diffuse Traumatic Brain Injury	Doctor of Philosophy	Doctorate	Full Time	Miss Alina Arulsamy
2014 - 2018	Co-Supervisor	Investigating Amyloid Precursor Protein Derivatives As Novel Therapeutic Agents Following Traumatic Brain Injury	Doctor of Philosophy	Doctorate	Full Time	Dr Stephanie Lauren Plummer
2014 - 2018	Co-Supervisor	The Role of Substance P in Chronic Traumatic Encephalopathy	Doctor of Philosophy	Doctorate	Full Time	Kelly Marie McAteer
2014 - 2022	Co-Supervisor	Experimental Models of Alcohol Induced Inflammation-associated Depressive-like Behaviour	Doctor of Philosophy	Doctorate	Part Time	Joshua Luke Holmes
2013 - 2019	Co-Supervisor	The Effects of Long-Term Exercise and Stopping Long-Term Exercise on Behaviours and Neurobiology	Doctor of Philosophy	Doctorate	Full Time	Ms Julie A Morgan
2013 - 2020	Co-Supervisor	The Differential Effects of Short-Term Physical Exercise, Environmental Enrichment and their Combination, and Short-and-Long-Term Environmental Enrichment on Behavior and Associated Molecular Changes in the Brain of C57BL/6 Mice	Doctor of Philosophy	Doctorate	Part Time	Dr Gaurav Singhal

Memberships

Date	Role	Membership	Country
2016 - ongoing	Member	Adelaide Centre for Neuroscience	Australia
2016 - ongoing	Member	Australian Society of Medical Research	Australia
2016 - ongoing	Member	Australian Neuroscience Society	Australia
2016 - ongoing	Member	International Neurotrauma Society	Australia

Position: Associate Prof/Reader
Phone: 83134150
Email: frances.corrigan@adelaide.edu.au
Fax: 83133356
Campus: North Terrace
Building: Helen Mayo South, floor 5
Org Unit: Medical Sciences

Dr Frances Corrigan

Research

Awards and Achievements

Journals

Book Chapters

Conference Papers

Conference Items

Current Higher Degree by Research Supervision (University of Adelaide)

Past Higher Degree by Research Supervision (University of Adelaide)

Memberships

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External Profiles