Frances Corrigan

Dr Frances Corrigan

Lecturer

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Dr Frances Corrigan - TITLEHOLDER.
I was awarded Australian Postgraduate Award (2009-11) to complete my PhD on the role of the amyloid precursor protein following traumatic brain injury at the University of Adelaide, which led to the successful identification of a potential novel therapeutic agent, in APP96-110. Upon completion of my PhD I was employed as a post-doctoral fellow in the laboratory of Professor Bernhard Baune investigating the effects of neuroinflammation on cognitive decline with aging, before accepting a position as a lecturer at the University of Adelaide. In this role I have continued to work with the APP96-110 peptide, while extending my research into the long-term consequences of traumatic brain injury, in particular its role in the later development of dementia. As such I have the necessary expertise required for this project encompassing models of traumatic brain injury, functional assessment, immunohistochemical analysis and molecular analysis. Despite a heavy teaching load and a break for maternity leave in 2014, my work has been extensively published, with 26 publications over the last 5 years in excellent journals such as Journal of Neuroinflammation, British Journal of Pharmacology and Neuropsychopharmacology. In recognition of the significance of my work, I was invited to speak in a symposia on mild traumatic brain injury at the leading conference in my field, the International Neurotrauma Society, in February 2016. Furthermore over the past 3 years I have secured over $50,000 in grant funding through 3 different granting bodies.

Research

I am the head of the Brain Injury Group, which liaises closely with the Translational Neuropathology lab . My research is primarily focussed on the mechanisms whereby concussion or mild traumatic brain injury can lead to the development of neurodegeneration, with particular interest in the role of neuroinflammation.  This research also aims to identify novel pharmacological agents to prevent the long-term consequences of concussion. 

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  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2017 Award South Australia Tall Poppy Australia
    2012 Achievement Fresh Science South Australian State Finalist Australia
    2012 Award Student Travel Award, International Neurotrauma Society
    2011 Award Faculty of Health Sciences Travel Award, University of Adelaide Australia
    2011 Award Student Travel Award, Australian Neuroscience Society Meeting Australia
    2010 Award School of Medical Sciences Travel Award, University of Adelaide Australia
    2010 Award Poster Prize- Faculty of Health Sciences Research Expo University of Adelaide Australia
    2010 Award Student Travel Award, Australian Neuroscience Society Meeting Australia
    2008 Scholarship Australian Postgraduate Research Award University of Adelaide

Corrigan F, Turner R, Abou-Hamden A. Targeting inflammation to prevent brain swelling following paediatric head injury

2019-2020: 214,500, James and Diana Ramsey Foundation

 

Corrigan F, Nasrallah F, Collins-Praino LE, Developing imaging biomarkers that predict pre-frontal cortex deficits following

concussive insults in adolescence. 2019: 35,246, Neurosurgical Research Foundation

 

Corrigan F, Vink R, Turner RJ, Van Den Heuvel C, Cappai R, Preclinical evaluation of the novel therapeutic compound

APP96-110 in an ovine model of traumatic brain injury. 2018-2020: 874,744.50. NHMRC

 

Corrigan F, Collins-Praino LE, The role of alcohol in promoting the development of neurodegeneration following repetitive

mild traumatic brain injury 2018: 24 440, Neurosurgical Research Foundation

                                       

Leonard AV, Corrigan F, Collins-Praino LE, Spinal Cord Injury Research Program – Equipment funding. 2016: 30,000,

Neurosurgical Research Foundation

 

Corrigan F. The role of the SP-NK1 system in promoting the vulnerability to concussion in adolescence. 2017: $19,000

Neurosurgical Research Foundation

 

Corrigan, F. Investigating the effects of toll-like receptor 4 activation on outcome following repeated concussion 2016: 22,000

Neurosurgical Research Foundation

                                          

Corrigan, F: Role of alcohol induced changes in the gut microbiome promotes the development of depression via induction of

a systemic inflammatory response. 2015: $19,000. School of Medical Sciences, Kick-Start Funding, University of Adelaide

 

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  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2019 Co-Supervisor Mechanisms by which Neuroinflammation mediates the development and progression of Parkinsons' Disease Doctor of Philosophy under a Jointly-awarded Degree Agreement with Doctorate Full Time Miss Ing Chee Wee
    2019 Co-Supervisor Treatment strategies for Cognitive impairment and dementia ini Parkinson's Disease Doctor of Philosophy Doctorate Full Time Miss Bianca Laura Guglietti
    2017 Co-Supervisor What are the mechanisms by increased vulnerability to concussion in adolescents Doctor of Philosophy Doctorate Full Time Miss Jessica May Sharkey
    2014 Co-Supervisor The Interaction Between Stress and Alcohol Induced Neuroinflammation on Depressive-like Behaviour Doctor of Philosophy Doctorate Part Time Joshua Luke Holmes
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2016 - 2019 Co-Supervisor From Trauma to Neurodegeneration: A One-Year Time Progression of Functional Impairments and its Associated Neuropathological Link Following Varied Severity of Experimental Diffuse Traumatic Brain Injury Doctor of Philosophy Doctorate Full Time Miss Alina Arulsamy
    2014 - 2018 Co-Supervisor Investigating Amyloid Precursor Protein Derivatives As Novel Therapeutic Agents Following Traumatic Brain Injury Doctor of Philosophy Doctorate Full Time Dr Stephanie Lauren Plummer
    2014 - 2018 Co-Supervisor The Role of Substance P in Chronic Traumatic Encephalopathy Doctor of Philosophy Doctorate Full Time Kelly Marie McAteer
    2013 - 2019 Co-Supervisor The Effects of Long-Term Exercise and Stopping Long-Term Exercise on Behaviours and Neurobiology Doctor of Philosophy Doctorate Full Time Ms Julie A Morgan
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  • Memberships

    Date Role Membership Country
    2016 - ongoing Member Adelaide Centre for Neuroscience Australia
    2016 - ongoing Member Australian Society of Medical Research Australia
    2016 - ongoing Member Australian Neuroscience Society Australia
    2016 - ongoing Member International Neurotrauma Society Australia
  • Position: Lecturer
  • Phone: 83134150
  • Email: frances.corrigan@adelaide.edu.au
  • Fax: 8313 3356
  • Campus: North Terrace
  • Building: Helen Mayo South, floor 5
  • Room: 5 24e
  • Org Unit: Medical Sciences

Connect With Me
External Profiles