Alan Brook
Adelaide Dental School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor Alan Brook
University of Adelaide, School of Dentistry.
Archaeology, Medical Anthropology, Biological Anthropology
D.D.SC(Adel) MDS(Lond) FDS.RCS(Eng)
Alan Brook is a leading figure internatioanlly in the the application of Complexity Science, Network Science and Modelling Influence on the development and functioning of the oral tissues. He has over 225 publications and over 270 abstracts of presentations with some 5,200 citations. Alan's research has ranged from basic science to clinical care to eductional research, arising from the varied aspects of his career as a clinical academic.
Clinically, hhis research has generated innovative diagnostic and treatment procedures for several oral conditions. This was combined with being Chief Executive Officer for a combined industry/ university research unit. In 2005, Alan was awarded the highest level (Platinum) NHS Clinical Excellence Award.
His eductaional research arose from curriculum innovations at undergraduate and postgraduate levels while holding the position of Head of Department and Deanship roles at several Universities and being President of the European Commission Dental Education Advisory Committee.
The major current and ongoing theme of his research relates to the development of the dentoalveolar complex from genotype to phenotype with an emphasis on the interactions between genetic, epigentic, and environmental factors. In 2014, Alan was awarded a Higher Doctorate, DDSc, of the University of Adelaide based on an international assessment of his published research. Since then, the work on Complexity, Networks and Models has developed with multicentre, multidiscplinary collaborators that Alan has inititated on "Hypodontia from genotype to phenotype" and "Tooth and dental arch variation intercat within a multilayer complex interactive network".
Research Interests
The overarching research theme is the application of Complexity Science, Network Science, and Multimodel approaches to Oro-facial development and function. Publications over the past decade have shown that the development and function of the dentoalveolar tissues are Complex Adaptive Systems based on Interactive Networks.
Recent publications address how the complex systems of the teeth and dental arches interact during development as a Multilayer Complex Interative Networks. These studies investiagate both modern and archaeological human samples.
Research Projects
Current:
- Developmental interactions in human dentition: the relationaship between variation in tooth number, size and shape, with dental arch morphology.
- 3D measurements using a new technique for teeth and dental arches in hypodontia and control patients. This project includes collaborators in New Zealand, U.S.A, U.K, Romania and Japan. Funding from International collaboration group memebers and from the Paul Kwok Lee Reseach Bequest.
- Development of teeth and dental arches in twins.
- Guest Editor for a Special Issue of ythe journal Genes entitled "Genes, Interactions and Dental Development: Advances in Understanding Genetics, Epigenetics and Environmental Interactions". This publication is due for completion in December 2022, with a subsquent book for which Alan will be the Editor.
Previous projects:
In Paediactric Dentistry
- Oro-facial Pathology
- Prevention of dental disease
- Patient management and treatment
Developments in Dental Education
- New Curricula
- Outreach in community placements
Dental Development and Variation
- Criteria for diagnosis
- New indices
- 2D customised image analysis systems
- 3D laser scanning
- Hypodontia, Supernumeraries and Amelogenesis Imperfecta
Modelling Dental Development
- Unifying model for tooth number and size
- Development and Testing of Models
Archaeological projects
- Romano-Britons - Dorchester, Baldock
- 19th-century migrant settlers to South Australia from Britain/ Europe
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Appointments
Date Position Institution name 2003 - 2005 Dean of Medical Faculty University of Sheffield -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title 2014 University of Adelaide Australiia D.D.Sc -
Certifications
Date Title Institution name Country 1968 Fellow in Dental Surgery FDS Royal College of Surgeons of England United Kingdom -
Research Interests
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Journals
Year Citation 2023 Paul, K. S., Feezell, R., Hughes, T., & Brook, A. H. (2023). Integrating genealogy and dental variation: contributions to biological anthropology. American Journal of Biological Anthropology, 181(S76), 145-179.
2023 Kerekes-Máthé, B., Mártha, K., Bănescu, C., O’Donnell, M. B., & Brook, A. H. (2023). Genetic and Morphological Variation in Hypodontia of Maxillary Lateral Incisors. Genes, 14(1), 13 pages.
Scopus12023 Gurr, A., Henneberg, M., Kumaratilake, J., Lerche, D., Richards, L., & Brook, A. H. (2023). The Oral Health of a Group of 19th Century South Australian Settlers in Relation to Their General Health and Compared With That of Contemporaneous Samples.
2023 Arshad, K., Ishfaq, U., Asif, M., Akbar, A., Pitafi, K. F., Mulghani, M. R., . . . Iqbal, F. (2023). Association of GSTTI, M1 and Polymorphism in GSTPI with Chronic Periodontal Disease in a Pakistani Population. Genes, 14(2), 10 pages.
2023 Gurr, A., Higgins, D., Henneberg, M., Kumaratilake, J., O'Donnell, M., McKinnon, M., . . . Brook, A. (2023). Investigating the dentoalveolar complex in archaeological human skull specimens: Additional Findings with large volume micro-CT compared to standard methods. International Journal of Osteoarchaeology, 33(2), 235-250.
Scopus1 WoS12023 Gurr, A., Henneberg, M., Kumaratilake, J., Lerche, D., Richards, L., & Brook, A. H. (2023). The Oral Health of a Group of 19th Century South Australian Settlers in Relation to Their General Health and Compared with That of Contemporaneous Samples. Dentistry Journal, 11(4), 28 pages.
2023 Giri, J., Bockmann, M., Brook, A., Farook, T. H., Meade, M., & Hughes, T. (2023). Heritability of dental arches and occlusal characteristics: a systematic review and meta-analysis. EUROPEAN JOURNAL OF ORTHODONTICS, 45(6), 14 pages.
2023 Giri, J., Hughes, T., Bockmann, M., & Brook, A. (2023). On dental arches of twins. American Journal of Orthodontics and Dentofacial Orthopedics, 164(4), 459.
2022 Gurr, A., Higgins, D., Henneberg, M., Kumaratilake, J., Brook O'Donnell, M., McKinnon, M., & Brook, A. H. (2022). Large Volume Micro-CT scanning of the dentoalveolar complex as a tool to evaluate dental health in an archaeological sample compared with traditional methods.
2022 Gurr, A., Kumaratilake, J., Brook, A. H., Ioannou, S., Pate, F. D., & Henneberg, M. (2022). Health effects of European colonization: An investigation of skeletal remains from 19th to early 20th century migrant settlers in South Australia. PLOS ONE, 17(4), 1-28.
Scopus3 WoS3 Europe PMC12022 Gurr, A., Brook, A. H., Kumaratilake, J., Anson, T., Pate, F. D., & Henneberg, M. (2022). Was it worth migrating to the new British industrial colony of South Australia? Evidence from skeletal pathologies and historic records of a sample of 19th-century settlers. International Journal of Paleopathology, 37, 41-52.
Scopus4 WoS4 Europe PMC12022 Paul, K., Stojnanowski, C., Hughes, T., Brook, A., & Townsend, G. (2022). Genetic correlation, pleiotropy, and molar morphology in a longitudinal sample of Australian twins and families. Genes, 13(6), 1-18.
Scopus2 WoS3 Europe PMC12022 Khalaf, K., Brook, A. H., & Smith, R. N. (2022). Genetic, Epigenetic and Environmental Factors Influence the Phenotype of Tooth Number, Size and Shape: Anterior Maxillary Supernumeraries and the Morphology of Mandibular Incisors. Genes, 13(12), 14 pages.
Scopus2 WoS1 Europe PMC12022 Al-Ansari, S., Jalali, R., Bronckers, A. L. J. J., van Tellingen, O., Raber-Durlacher, J., Nadjmi, N., . . . Rozema, F. R. (2022). Tooth Formation as Experimental Model to Study Chemotherapy on Tissue Development: Effect of a Specific Dose of Temozolomide/Veliparib. Genes, 13(7), 11 pages.
2021 Paul, K., Stojanowski, C., Hughes, T., Brook, A., & Townsend, G. (2021). The genetic architecture of anterior tooth morphology in a longitudinal sample of Australian twins and families. Archives of Oral Biology, 129, 105168-1-105168-11.
Scopus5 WoS5 Europe PMC32021 Gurr, A., Kumaratilake, J., Brook, A. H., Ioannou, S., Pate, F. D., & Henneberg, M. (2021). Health effects of European colonization: An investigation of skeletal remains from 19th to early 20th-century migrant settlers in South Australia.
2020 Paul, K., Stojanowski, C., Hughes, T. E., Brook, A., & Townsend, G. (2020). Patterns of heritability across the human diphyodont dental complex: Crown morphology of Australian twins and families. American Journal of Physical Anthropology, 172(3), 447-461.
Scopus13 WoS14 Europe PMC52020 Choi, G. P. T., Chan, H. L., Yong, R., Ranjitkar, S., Brook, A., Townsend, G., . . . Lui, L. M. (2020). Tooth morphometry using quasi-conformal theory. Pattern Recognition, 99, 11 pages.
Scopus15 WoS122019 Tadros, M., Brook, A. H., Ranjitkar, S., & Townsend, G. C. (2019). Compensatory interactions between developing maxillary anterior teeth in a sample of twins. Archives of Oral Biology, 97, 198-207.
Scopus6 WoS3 Europe PMC12019 Brook, A. H., Paul, K., Stojanowski, C., Hughes, T., & Townsend, G. C. (2019). Patterns of morphological pleiotrophy in the human diphyodont dentition.. American Journal of Physical Anthropology. 2018 Patel, D., Sassani, S., Farella, M., Ranjitkar, S., Yong, R., Swindells, S., & Brook, A. (2018). Variations in dental arch morphology are outcomes of the complex adaptive system associated with the developmental variation of hypodontia. International Journal of Design and Nature and Ecodynamics, 13(1), 107-113.
Scopus32018 Chen, L., Liversidge, H., Chen, K., Farella, M., Sassani, S., Patel, D., . . . Brook, A. (2018). Delay in dental development and variations in root morphology are outcomes of the complex adaptive system associated with the numerical variation of hypodontia. International Journal of Design and Nature and Ecodynamics, 13(1), 101-106.
2018 Kitson, A., Brook, A., Harvey, G., Jordan, Z., Marshall, R., O'Shea, R., & Wilson, D. (2018). Using complexity and network concepts to inform healthcare knowledge translation. International Journal of Health Policy and Management, 7(3), 231-243.
Scopus90 WoS66 Europe PMC422018 Taduran, R. J., Ranjitkar, S., Hughes, T. E., Townsend, G. C., & Brook, A. (2018). Two complex adaptive systems in human development: further studies of dental and fingerprint parameters. International Journal of Design and Nature and Ecodynamics, 13(1), 93-100.
2018 Yong, R., Ranjitkar, S., Lekkas, D., Halazonetis, D., Evans, A., Brook, A., & Townsend, G. (2018). Three-dimensional (3D) geometric morphometric analysis of human premolars to assess sexual dimorphism and biological ancestry in Australian populations. American Journal of Physical Anthropology, 166(2), 373-385.
Scopus19 WoS18 Europe PMC102018 Kitson, A., O’Shea, R., Brook, A., Harvey, G., Jordan, Z., Marshall, R., & Wilson, D. (2018). The knowledge translation complexity network (KTCN) model: The whole is greater than the sum of the parts - A response to recent commentaries. International Journal of Health Policy and Management, 7(8), 768-770.
Scopus4 WoS2 Europe PMC22018 Sassani, S., Patel, D., Farella, M., Henneberg, M., Ranjitkar, S., Yong, R., . . . Brook, A. (2018). Variation in tooth crown size and shape are outcomes of the complex adaptive system associated with the tooth number variation of hypodontia. International Journal of Design and Nature and Ecodynamics, 13(1), 114-120.
Scopus32017 Ranjitkar, S., Turan, A., Mann, C., Gully, G., Marsman, M., Edwards, S., . . . Townsend, G. (2017). Surface-sensitive microwear texture analysis of attrition and erosion. Journal of Dental Research, 96(3), 300-307.
Scopus17 WoS13 Europe PMC62017 Taduran, R., Ishimura, R., Rosario, M., Brook, A., & Townsend, G. (2017). Sex variation in fingerprint ridge counts in Filipinos. European Journal of Forensic Sciences, 1.
2016 Patel, P., Yong, R., Ranjitkar, S., Townsend, G., & Brook, A. (2016). Agents within a developmental complex adaptive system: Intrauterine male hormones and dental arch size in humans. Proceedings of the New Forest Conference on Complex Systems 2016, as published in International Journal of Design and Nature and Ecodynamics, 11(4), 703-711.
Scopus12016 Lam, F., Yong, R., Ranjitkar, S., Townsend, G., & Brook, A. (2016). Agents within a developmental complex adaptive system: Intrauterine male hormones influence human tooth size and shape. Proceedings of the New Forest Conference on Complex Systems 2016, as published in International Journal of Design and Nature and Ecodynamics, 11(4), 696-702.
Scopus32016 Kaidonis, J. A., Ranjitkar, S., Townsend, G. C., Koh, K. S. B., Toh, V. K. L., & Brook, A. H. (2016). The mature stomatognathic system is a Complex Adaptive System. International Journal of Design and Nature and Ecodynamics, 11(4), 670-675.
Scopus32016 Taduran, R., Ranjitkar, S., Hughes, T., Townsend, G., & Brook, A. (2016). Complex Systems in Human Development: Sexual Dimorphism in Teeth and Fingerprints of Australian Twins. Proceedings of the New Forest Conference on Complex Systems 2016, as published in International Journal of Design & Nature and Ecodynamics, 11(4), 676-685.
Scopus32016 Brook, A. H., Koh, K. S. B., & Toh, V. K. L. (2016). Influences in a biologically complex adaptive system: Environmental stress affects dental development in a group of Romano-Britons. International Journal of Design and Nature and Ecodynamics, 11(1), 33-40.
Scopus72016 Odeh, R., Mihailidis, S., Townsend, G., Lähdesmäki, R., Hughes, T., & Brook, A. (2016). Prevalence of infraocclusion of primary molars determined using a new 2D image analysis methodology. Australian Dental Journal, 61(2), 183-189.
Scopus13 WoS14 Europe PMC92015 Odeh, R., Townsend, G., Mihailidis, S., Lähdesmäki, R., Hughes, T., & Brook, A. (2015). Infraocclusion: dental development and associated dental variations in singletons and twins. Archives of Oral Biology, 60(9), 1394-1402.
Scopus10 WoS9 Europe PMC62015 Kerekes-Máthé, B., Brook, A., Mártha, K., Székely, M., & Smith, R. (2015). Mild hypodontia is associated with smaller tooth dimensions and cusp numbers than in controls. Archives of Oral Biology, 60(9), 1442-1449.
Scopus13 WoS10 Europe PMC42015 Sreekumar, J., France, N., Taylor, S., Matthews, T., Turner, P., Bliss, P., . . . Watson, A. (2015). Diagnosis of Helicobacter pylori by carbon-13 urea breath test using a portable mass spectrometer. SAGE open medicine, 3, 1-6.
Scopus10 WoS7 Europe PMC22014 Hughes, T., Townsend, G., Pinkerton, S., Bockmann, M., Seow, W., Brook, A., . . . Lekkas, D. (2014). The teeth and faces of twins: providing insights into dentofacial development and oral health for practising oral health professionals. Australian Dental Journal, 59(Suppl. 1), 101-116.
Scopus42 WoS36 Europe PMC152014 Mann, C., Ranjitkar, S., Lekkas, D., Hall, C., Kaidonis, J., Townsend, G., & Brook, A. (2014). Three-dimensional profilometric assessment of early enamel erosion simulating gastric regurgitation. Journal of Dentistry, 42(11), 1411-1421.
Scopus23 WoS20 Europe PMC132014 Brook, A., Jernvall, J., Smith, R., Hughes, T., & Townsend, G. (2014). The dentition: the outcomes of morphogenesis leading to variations of tooth number, size and shape. Australian Dental Journal, 59(Suppl. 1), 131-142.
Scopus67 WoS55 Europe PMC302014 Townsend, G. C., & Brook, A. H. (2014). The face, the future, and dental practice: how research in craniofacial biology will influence patient care. Australian Dental Journal, 59(Suppl. 1), 1-5.
Scopus3 WoS5 Europe PMC32014 Brook, A., O'Donnell, M., Hone, A., Hart, E., Hughes, T., Smith, R., & Townsend, G. (2014). General and craniofacial development are complex adaptive processes influenced by diversity. Australian Dental Journal, 59(Suppl. 1), 13-22.
Scopus30 WoS20 Europe PMC82014 Williams, S., Hughes, T., Adler, C., Brook, A., & Townsend, G. (2014). Epigenetics: a new frontier in dentistry. Australian Dental Journal, 59(Suppl. 1), 23-33.
Scopus34 WoS25 Europe PMC52014 Kaidonis, J., Ranjitkar, S., Lekkas, D., Brook, A., & Townsend, G. (2014). Functional dental occlusion: an anthropological perspective and implications for practice. Australian Dental Journal, 59(Suppl. 1), 162-173.
Scopus21 WoS17 Europe PMC92014 Redwood, C., Townsend, G., Ghabriel, M., & Brook, A. (2014). Under your nose: a rare finding during dissection provides insights into maxillary supernumerary teeth. Australian Dental Journal, 59(3), 379-385.
Scopus1 WoS1 Europe PMC12014 Yong, R., Ranjitkar, S., Townsend, G., Smith, R., Evans, A., Hughes, T., . . . Brook, A. (2014). Dental phenomics: advancing genotype to phenotype correlations in craniofacial research. Australian Dental Journal, 59(Suppl. 1), 34-47.
Scopus26 WoS24 Europe PMC102013 Brook, A. H., Hughes, T. E., Townsend, G. C., Smith, R. N., & O'Donnell, M. D. B. (2013). The development of the mammalian dentition as a complex adaptive system. Dental Anthropology, 26(3), 3-6.
2013 Ribeiro, D., Brook, A., Hughes, T., Sampson, W., & Townsend, G. (2013). Intrauterine hormone effects on tooth dimensions. Journal of Dental Research, 92(5), 425-431.
Scopus54 WoS42 Europe PMC222013 Hughes, T., Bockmann, M., Mihailidis, S., Bennett, C., Harris, A., Seow, W., . . . Townsend, G. (2013). Genetic, epigenetic, and environmental influences on dentofacial structures and oral health: Ongoing studies of australian twins and their families. Twin Research and Human Genetics, 16(1), 43-51.
Scopus26 WoS26 Europe PMC132013 Brook, A. H., Mihailidis, S., Ashar, A., Hughes, T., Bockmann, M., & Townsend, G. (2013). Dental Phenomics: High tech scans reveal similarities and differences in monozygotic twins.. Twin Research and Human Genetics, (16), 43-51.
2012 Brook, A., & Brook O'Donnell, M. (2012). Modelling the Complexity of Dentition. New directions in Dental Anthropology, 1-9. 2012 Brook, A., Townsend, G. C., Brockman, M., Hughes, T., Mihailidis, S., & Seow, W. K. (2012). New Approaches to Dental Anthropology based on the study of twins. New Directions in Dental Anthropology. 2012 Brook, A., Ribeiro, D., Sampson, W., Hughes, T., & Townsend, G. C. (2012). Sexual dimorphism in the primary and permanent dentition of twins : an approach to clarify the role of hormonal factors. New Directions in Dental Anthropology. 2012 Coxon, T. L., Brook, A. H., Barron, M. J., & Smith, R. N. (2012). Phenotype-genotype correlations in mouse models of amelogenesis imperfecta caused by amelx and enam mutations. Cells Tissues Organs, 196(5), 420-430.
Scopus11 WoS12 Europe PMC62012 Townsend, G., Bockmann, M., Hughes, T., & Brook, A. (2012). Genetic, environmental and epigenetic influences on variation in human tooth number, size and shape. Odontology, 100(1), 1-9.
Scopus85 WoS76 Europe PMC352011 Griffin, R., Pitts, M., Smith, R., & Brook, A. (2011). Inequality at late Roman baldock, UK: The impact of social factors on health and diet. Journal of Anthropological Research, 67(4), 533-556.
Scopus12 WoS102011 Brook, A., & Brook O'Donnell, M. (2011). The Dentition: A Complex System Demonstrating Self Principles. Fifth International Conference of Self Adaptive and Self Organizing Systems. C.P.S., 208-209.
2010 Shore, R. C., Bäckman, B., Elcock, C., Brook, A. H., Brookes, S. J., & Kirkham, J. (2010). The structure and composition of deciduous enamel affected by local hypoplastic autosomal dominant amelogenesis imperfecta resulting from an ENAM mutation. Cells Tissues Organs, 191(4), 301-306.
Scopus10 WoS9 Europe PMC52009 Smith, R. N., Elcock, C., Abdellatif, A., Bäckman, B., Russell, J. M., & Brook, A. H. (2009). Enamel defects in extracted and exfoliated teeth from patients with Amelogenesis Imperfecta, measured using the extended enamel defects index and image analysis. Archives of Oral Biology, 54(SUPPL. 1), S86-S92.
Scopus7 WoS8 Europe PMC42009 Parkin, N., Elcock, C., Smith, R. N., Griffin, R. C., & Brook, A. H. (2009). The aetiology of hypodontia: The prevalence, severity and location of hypodontia within families. Archives of Oral Biology, 54(SUPPL. 1), S52-S56.
Scopus31 WoS30 Europe PMC142009 Hobson, G. M., Gibson, C. W., Aragon, M., Yuan, Z. A., Davis-Williams, A., Banser, L., . . . Brook, A. H. (2009). A large X-chromosomal deletion is associated with microphthalmia with linear skin defects (MLS) and amelogenesis imperfecta (XAI). American Journal of Medical Genetics, Part A, 149(8), 1698-1705.
Scopus15 WoS14 Europe PMC122009 Brook, A. (2009). Research collaboration initiative. Archives of Oral Biology, 54(SUPPL. 1), S1-S2.
Scopus2 WoS32009 Khalaf, K., Smith, R. N., Elcock, C., & Brook, A. H. (2009). Multiple crown size variables of the upper incisors in patients with supernumerary teeth compared with controls. Archives of Oral Biology, 54(SUPPL. 1), S71-S78.
Scopus14 WoS12 Europe PMC82009 Lesot, H., & Brook, A. H. (2009). Epithelial histogenesis during tooth development. Archives of Oral Biology, 54(SUPPL. 1), S25-S33.
Scopus55 WoS56 Europe PMC382009 Brook, A. H. (2009). Multilevel complex interactions between genetic, epigenetic and environmental factors in the aetiology of anomalies of dental development. Archives of Oral Biology, 54(SUPPL. 1), S3-S17.
Scopus169 WoS147 Europe PMC902009 Brook, A. H., Elcock, C., Aggarwal, M., Lath, D. L., Russell, J. M., Patel, P. I., & Smith, R. N. (2009). Tooth dimensions in hypodontia with a known PAX9 mutation. Archives of Oral Biology, 54(SUPPL. 1), S57-S62.
Scopus32 WoS29 Europe PMC202009 Townsend, G., Hughes, T., Luciano, M., Bockmann, M., & Brook, A. (2009). Genetic and environmental influences on human dental variation: A critical evaluation of studies involving twins. Archives of Oral Biology, 54(Suppl 1), 45-51.
Scopus122 WoS108 Europe PMC642009 Smith, R., Zaitoun, H., Coxon, T., Karmo, M., Kaur, G., Townsend, G., . . . Brook, A. (2009). Defining new dental phenotypes using 3-D image analysis to enhance discrimination and insights into biological processes. Archives of Oral Biology, 54(Supp 1), 118-125.
Scopus25 WoS23 Europe PMC132009 Brook, A., Griffin, R., Townsend, G., Levisianos, Y., Russell, G., & Smith, R. (2009). Variability and patterning in permanent tooth size of four human ethnic groups. Archives of Oral Biology, 54(Supp 1), S79-S85.
Scopus69 WoS58 Europe PMC342009 Brook, A., Griffin, R., Smith, R., Townsend, G., Kaur, G., Davis, G., & Fearne, J. (2009). Tooth size patterns in patients with hypodontia and supernumerary teeth. Archives of Oral Biology, 54(Suppl 1), S63-S70.
Scopus54 WoS47 Europe PMC302009 Brook, A. (2009). Clinical Aspects of Dental Morphology: An Introduction. Comparative Dental Morphology, Frontiers of Oral Biology, 13, 134-135. 2009 Brook, A., Horrock, L., Alvesale, L., & Smith, R. N. (2009). A three-dimensional comparison of the Modifying Effects of familial Genetic Contribution in Turner Syndrome. Comparative Dental Morphology, Frontiers of Oral Biology, 148-152. 2009 Brook, A., Townsend, G. C., Hughes, T., & Smith, R. N. (2009). How studies of the twins can inform our understanding of dental morphology. Comparative Dental Morphology, Frontiers of Oral Biology, 13, 136-141. 2009 Brook, A., Smith, R. N., Townsend, G. C., & Chen, K. (2009). Synetic Superimposition of Dental 3D data Application in Twin Studies. Comparative Dental Morphology, Frontiers of Oral Biology, 13, 142-147. 2008 Smith, R. N., Lath, D. L., Rawlinson, A., Karmo, M., & Brook, A. H. (2008). Gingival inflammation assessment by image analysis: measurement and validation.. International journal of dental hygiene, 6(2), 137-142.
Scopus18 Europe PMC92008 Townsend, G., Alvesalo, L., & Brook, A. (2008). Variation in the human dentition: Some past advances and future opportunities. Journal of Dental Research, 87(9), 802-805.
Scopus5 WoS4 Europe PMC42008 Townsend, G. C., & Brook, A. (2008). Genetic, epigenetic and environmental influences on dental development. Ortho Tribune, 3(4), 3-6. 2007 Brook, A. H., Smith, R. N., & Lath, D. J. (2007). The clinical measurement of tooth colour and stain. International Dental Journal, 57(5), 324-330.
Scopus56 WoS40 Europe PMC262007 Lath, D. L., Wildgoose, D. G., Guan, Y. H., Lilley, T. H., Smith, R. N., & Brook, A. H. (2007). A digital image analysis system for the assessment of tooth whiteness compared to visual shade matching. Journal of Clinical Dentistry, 18(1), 17-20.
Scopus14 Europe PMC42007 Smith, R. N., Karmo, M., Russell, J., & Brook, A. H. (2007). The variability of the curvature of the labial surface of the upper anterior teeth along the facial axis of the clinical crown. Archives of Oral Biology, 52(11), 1037-1042.
Scopus13 WoS10 Europe PMC62007 Lath, D. L., Smith, R. N., Guan, Y. H., Karmo, M., & Brook, A. H. (2007). Measurement of stain on extracted teeth using spectrophotometry and digital image analysis.. International journal of dental hygiene, 5(3), 174-179.
Scopus13 Europe PMC72006 DiBiase, A. T., Elcock, C., Smith, R. N., & Brook, A. H. (2006). A new technique for symmetry determination in tooth morphology using image analysis: Application in the diagnosis of solitary maxillary median central incisor. Archives of Oral Biology, 51(10), 870-875.
Scopus10 WoS9 Europe PMC32006 Smith, M., Lennon, M. A., Brook, A. H., & Robinson, P. G. (2006). A randomized controlled trial of outreach placement's effect on dental students' clinical confidence.. Journal of dental education, 70(5), 566-570.
Scopus54 Europe PMC242006 Smith, M., Lennon, M. A., Brook, A. H., Ritucci, L., & Robinson, P. G. (2006). Student perspectives on their recent dental outreach placement experiences. European Journal of Dental Education, 10(2), 80-86.
Scopus39 Europe PMC212006 Lath, D. L., Wildgoose, D. G., Guan, H., Lilley, T. H., Smith, R. N., & Brook, A. H. (2006). Visual whiteness ranking of a Vitapan 3D Master shade guide by untrained assessors. Journal of Clinical Dentistry, 17(1), 10-13.
Scopus11 Europe PMC62006 Smith, M., Lennon, M. A., Brook, A. H., & Robinson, P. G. (2006). Perspectives of staffon student outreach placements. European Journal of Dental Education, 10(1), 44-51.
Scopus21 Europe PMC162006 Lath, D. L., Johnson, C., Smith, R. N., & Brook, A. H. (2006). Measurement of stain removal in vitro: a comparison of two instrumental methods.. International journal of dental hygiene, 4(3), 129-132.
Scopus11 Europe PMC102006 Smith, M., Lennon, M. A., Brook, A. H., Blinkhorn, F. A., Blinkhorn, A. S., & Robinson, P. G. (2006). A randomised controlled trial of the effect of outreach placement on treatment planning by dental students. British Dental Journal, 201(s5), 27-31.
Scopus26 Europe PMC72006 Smith, R. N., Rawlinson, A., Lath, D. L., & Brook, A. H. (2006). A digital SLR or intra-oral camera: Preference for acquisition within an image analysis system for measurement of disclosed dental plaque area within clinical trials. Journal of Periodontal Research, 41(1), 55-61.
Scopus16 WoS16 Europe PMC102005 Khalaf, K., Robinson, D., Elcock, C., Smith, R., & Brook, A. (2005). Tooth size in patients with supernumerary teeth and a control group measured by image analysis system. Archives of Oral Biology, 50(2), 243-248.
Scopus27 WoS20 Europe PMC132005 Kirkham, J., Kaur, R., Stillman, E., Blackwell, P., Elcock, C., & Brook, A. (2005). The patterning of hypodontia in a group of young adults in Sheffield, UK. Archives of Oral Biology, 50(2), 287-291.
Scopus23 WoS19 Europe PMC72005 Smith, R., Collins, L., Naeeni, M., Joiner, A., Philpotts, C., Hopkinson, I., . . . Brook, A. (2005). The in vitro and in vivo validation of a mobile non-contact camera-based digital imaging system for tooth colour measurement. Journal of Dentistry, 36(S1), 15-20.
Scopus25 WoS28 Europe PMC72005 Guan, Y., Lath, D., Lilley, T., Willmot, D., Marlow, I., & Brook, A. (2005). The measurement of tooth whiteness by image analysis and spectrophotometry: a comparison. Journal of Oral Rehabilitation, 32(1), 7-15.
Scopus62 WoS49 Europe PMC452005 Brook, A., Lath, D., Brook, B. J., & Smith, R. N. (2005). Further consideration of the aetiology of developmental defects of the dentition. Current Trends in Dental Morphology Research, 467-474. 2005 Brook, A., Smith, R. N., & Karmo, M. (2005). Rotational principle component analysis to show relationships of descriptive labial surface variables on maxillary teeth. Current Trends in Dental Morphology Research, 541-584. 2004 Brook, A., Harris, J. C., Elcock, C., & Craig, G. T. (2004). Developmental Dental Defects in a Child of a Methadone User. International Journal of Paediatric Dentistry, 396-400. 2004 Smith, R. N., Rawlinson, A., Lath, D., Elcock, C., Walsh, T. F., & Brook, A. H. (2004). Quantification of dental plaque on lingual tooth surfaces using image analysis: Reliability and validation. Journal of Clinical Periodontology, 31(7), 569-573.
Scopus19 WoS14 Europe PMC132003 Peck, S., Shah, A. A., Elcock, C., & Brook, A. H. (2003). Crown dimensions and the alignment or crowding of mandibular incisors [3] (multiple letters). American Journal of Orthodontics and Dentofacial Orthopedics, 124(4), 20A-21A.
Scopus1 Europe PMC22003 Guan, Y. H., Lath, D. L., De Graaf, T., Lilley, T. H., & Brook, A. H. (2003). Moderation of oral bacterial adhesion on saliva-coated hydroxyapatite by polyaspartate. Journal of Applied Microbiology, 94(3), 456-461.
Scopus20 WoS18 Europe PMC102003 Das, P., Hai, M., Elcock, C., Leal, S. M., Brown, D. T., Brook, A. H., & Patel, P. I. (2003). Novel missense mutations and a 288-bp exonic insertion in PAX9 in families with autosomal dominant hypodontia. American Journal of Medical Genetics, 118 A(1), 35-42.
Scopus106 WoS94 Europe PMC742003 Shah, A. A., Elcock, C., & Brook, A. H. (2003). Incisor crown shape and crowding. American Journal of Orthodontics and Dentofacial Orthopedics, 123(5), 562-567.
Scopus14 WoS10 Europe PMC72003 Guan, Y. H., Lilley, T. H., Lath, D. L., Marlow, I., & Brook, A. H. (2003). Synergy of binary poly(oxypropylene-oxyethylene) copolymers in reducing retention of Streptococcus sanguis to hydroxyapatite. Caries Research, 37(1), 71-78.
Scopus3 WoS2 Europe PMC22002 McKeown, H. F., Robinson, D. L., Elcock, C., Al-Sharood, M., & Brook, A. H. (2002). Tooth dimensions in hypodontia patients, their unaffected relatives and a control group measured by a new image analysis system. European Journal of Orthodontics, 24(2), 131-141.
Scopus60 WoS55 Europe PMC342002 Robinson, D. L., Blackwell, P. G., Stillman, E. C., & Brook, A. H. (2002). Impact of landmark reliability on the planar Procrustes analysis of tooth shape. Archives of Oral Biology, 47(7), 545-554.
Scopus30 WoS24 Europe PMC142002 Brook, A. H., Elcock, C., Al-Sharood, M. H., McKeown, H. F., Khalaf, K., & Smith, R. N. (2002). Further studies of a model for the etiology of anomalies of tooth number and size in humans. Connective Tissue Research, 43(2-3), 289-295.
Scopus67 WoS58 Europe PMC492001 Smith, R. N., Brook, A. H., & Elcock, C. (2001). The quantification of dental plaque using an image analysis system: Reliability and validation. Journal of Clinical Periodontology, 28(12), 1158-1162.
Scopus58 WoS42 Europe PMC292001 Guan, Y. H., Lilley, T. H., & Brook, A. H. (2001). Production of immobilized penicillin acylase using aqueous polymer systems for enzyme purification and in situ immobilization. Enzyme and Microbial Technology, 28(2-3), 218-224.
Scopus16 WoS15 Europe PMC42001 Guan, Y. H., De Graaf, T., Lath, D. L., Humphreys, S. M., Marlow, I., & Brook, A. H. (2001). Selection of oral microbial adhesion antagonists using biotinylated Streptococcus sanguis and a human mixed oral microflora. Archives of Oral Biology, 46(2), 129-138.
Scopus10 WoS7 Europe PMC62001 Robinson, D. L., Blackwell, P. G., Stillman, E. C., & Brook, A. H. (2001). Planar Procrustes analysis of tooth shape. Archives of Oral Biology, 46(3), 191-199.
Scopus25 WoS20 Europe PMC122001 Peariasamy, K., Anderson, P., & Brook, A. H. (2001). A quantitative study of the effect of pumicing and etching on the remineralisation of enamel opacities. International Journal of Paediatric Dentistry, 11(3), 193-200.
Scopus19 Europe PMC102001 Blankenstein, R., Brook, A. H., Smith, R. N., Patrick, D., & Russell, J. M. (2001). Oral findings in Carpenter Syndrome. International Journal of Paediatric Dentistry, 11(5), 352-360.
2001 Brook, A., Elcock, C., Hallonsten, A., Poulson, J., Andreasen, J., Koch, G., & Yeung, C. A. (2001). The Development of a New Index to Measure Enamel Defects. Dental Morphology, 59-65. 2001 Brook, A., Robinson, D. L., Blackwell, P. G., & Stillman, E. C. (2001). Development of a Coherent Methodology for the Analysis of Tooth Shape. Dental Morphology, 219-227. 2001 Brook, A., Lath, D., Lilley, T., & Guan, Y. H. (2001). Comparison of Colorimetry and Image Analysis for Quantifying Tooth Whiteness - a Preliminary Study. Dental Morphology, 229-237. 2001 Brook, A., Nelson, T. A. B., Willmot, D. R., Elcock, C., Smith, R. N., & Robinson, D. L. (2001). Use of Computerised Image Analysis to Measure the form and Dimensions of the Maxillary Dental Arches in Subjects with Hypodontia. Dental Morphology, 239-253. 2001 Brook, A., Shah, A. A., Elcock, C., & Smith, R. N. (2001). Relationship Between Lower Incisor Crowding and the Facio-lingual Widths of Incisors at the Contact Point Level Using a New Image Analysis System. Dental Morphology, 299-306. 2001 Brook, A., Khalaf, K., Robinson, D. L., Elcock, C., & Smith, R. N. (2001). Determination and Comparison of Size variables of Upper Central Incisors in Patients with Supernumerary Teeth. Dental Morphology, 343-350. 2000 Kindelan, S. A., Brook, A. H., Gangemi, L., Lench, N., Wong, F. S. L., Fearne, J., . . . Stringer, B. M. J. (2000). Detection of a novel mutation in X-linked amelogenesis imperfecta. Journal of Dental Research, 79(12), 1978-1982.
Scopus45 WoS39 Europe PMC352000 Willmot, D. R., Benson, P. E., Pender, N., & Brook, A. M. (2000). Reproducibility of Quantitative Measurement of White Enamel Demineralisation by Image Analysis. Caries Research, 34(2), 175-181.
Scopus24 WoS21 Europe PMC151999 Brook, A., Smith, J. M., Smith, R. N., & Elcock, C. (1999). Timing of permanent tooth eruption in London School Children. Dental Morphology 1998, Proceedings of the 11th International Symposium,, 187-191. 1999 Brook, A. (1999). A unifying model for the aetiology of enamel defects. Dental Morphology 1998, Proceeding of the 11th International Symposium, 128-132. 1999 Brook, A., Smith, R. N., Elcock, C., Al-Sharood, M., Shah, A., & Karmo, M. (1999). The measurement of tooth morphology: Development and validation of a new image analysis technique. Dental Morphology 1998, Proceedings of the 11th International Symposium on Dental Morphology, 380-387. 1999 Brook, A., Wilmot, D. R., & Smith, R. N. (1999). Dimensional measurements of enamel lesions by computerised image analysis and processing. Dental Morphology 1998, Proceedings of the 11th International Symposium on Dental Morphology, 398-405. 1998 Brook, A. H., & Smith, J. M. (1998). The aetiology of developmental defects of enamel: A prevalence and family study in east London, U.K.. Connective Tissue Research, 39(1-3), 151-156.
Scopus26 Europe PMC201997 Wong, F. S. L., Fearne, J. M., & Brook, A. H. (1997). Planning future general anaesthetic services in paediatric dentistry on the basis of evidence: An analysis of children treated in the Day Stay Centre at the Royal Hospitals NHS Trust, London, between 1985-95. International Dental Journal, 47(5), 285-292.
Scopus24 Europe PMC151997 Brook, A. H., Fearne, J. M., & Smith, J. M. (1997). Environmental causes of enamel defects. CIBA Foundation Symposia, 205(205), 212-225.
Scopus35 WoS29 Europe PMC121997 Fry, H., Jones, A., Davenport, E., & Brook, A. (1997). Changing curricula: An evaluation from dentistry. Medical Teacher, 19(2), 108-113.
Scopus11997 Lench, N. J., & Brook, A. H. (1997). DNA diagnosis of X-linked amelogenesis imperfecta (AIH1). Journal of Oral Pathology and Medicine, 26(3), 135-137.
Scopus10 WoS7 Europe PMC71996 Brook, A., Roberts, G., Page, J., & Davenport, E. (1996). Indications for the use of inhalation sedation. International Journal of Paediatric Dentistry, 6, 63-66. 1995 Johns, C. C., & Brook, A. (1995). Dental Anomalies of Number and Size in a Romano-British Population. Proceedings of the !0th International Symposium On Dental Morphology, 177-180. 1994 Lench, N. J., Brook, A. H., & Winter, G. B. (1994). SSCP detection of a nonsense mutation in exon 5 of the amelogenin gene (AMGX) causing X-linked amelogenesis imperfecta (AIH1). Human Molecular Genetics, 3(5), 827-828.
Scopus63 WoS62 Europe PMC491993 Fearne, J. M., & Brook, A. H. (1993). Small primary tooth-crown size in low birthweight children. Early Human Development, 33(2), 81-90.
Scopus33 WoS29 Europe PMC261992 Brook, A. (1992). A Review of the Developmental Defacts of Enamel Index (D.D.E Index). International Dental Journal, 42, 411-426. 1990 Fearne, J. M., Bryan, E. M., Elliman, A. M., Brook, A. H., & Williams, D. M. (1990). Enamel defects in the primary dentition of children born weighing less than 2000 g. British Dental Journal, 168(11), 433-437.
Scopus69 WoS45 Europe PMC351988 Brook, A. (1988). Consent for Dental Care of Handicapped Patients. Journal for the Medical Defence Union, 2, 43. 1986 Fearne, J., Williams, D. M., & Brook, A. H. (1986). Regional odontodysplasia: a clinical and histological evaluation.. Journal of the International Association of Dentistry for Children, 17(1), 21-25.
Scopus21 Europe PMC131986 Davis, P. J., & Brook, A. H. (1986). The presentation of talon cusp: Diagnosis, clinical features, associations and possible aetiology. British Dental Journal, 160(3), 84-88.
Scopus116 WoS47 Europe PMC431986 Brook, A. H., Yau, F., Sandar, P. K., & Pitts, N. B. (1986). An Image Analysis System for the Determination of Tooth Dimensions from Study Casts: Comparison with Manual Measurements of Mesio-distal Diameter. Journal of Dental Research, 65(3), 428-431.
Scopus8 WoS9 Europe PMC51985 O'Donnell, D., Brook, A. H., & Ma, G. (1985). Bilateral, asymmetrical, complete oroocular facial clefts and supernumerary teeth in a young Chinese female.. ASDC journal of dentistry for children, 52(3), 191-194.
Scopus7 WoS6 Europe PMC21985 Brook, A. H., Bedi, R., Chan Lui, W. Y., & Yuen, P. M. P. (1985). Haemophilic pseudotumours of the mandible: Report of a case in a one-year-old child. British Journal of Oral and Maxillofacial Surgery, 23(1), 47-52.
Scopus15 WoS13 Europe PMC81985 Brook, A., Davis, P. J., King, N. M., Evans, R. W., Taylor, C. E., & Woo, R. (1985). The Dental Treatment Needs of Handicapped Children and Young Adults in Hong Kong. Journal of the International Association of Dentistry for Children, 16, 33-37. 1984 King, N. M., Brook, A. H., & Page, J. (1984). Paedodontics. 3. Endodontic therapy for primary teeth: II. Materials.. Dental update, 11(4), 220-228.
Scopus11984 Bedi, R., King, N. M., & Brook, A. H. (1984). Paedodontics. 4. Local anaesthesia for children: recent developments.. Dental update, 11(5), 283-288.
Scopus2 Europe PMC21984 King, N. M., Bedi, R., & Brook, A. H. (1984). Paedodontics. 1. Isolation techniques.. Dental update, 11(2), 91-94.
Europe PMC11984 King, N. M., Brook, A. H., & Page, J. (1984). Endodontic therapy for primary teeth. I. Diagnosis and treatment.. Dental update, 11(3), 154-passim.
Scopus11984 Brook, A. H. (1984). A unifying aetiological explanation for anomalies of human tooth number and size. Archives of Oral Biology, 29(5), 373-378.
Scopus331 WoS291 Europe PMC2011984 King, N. M., & Brook, A. H. (1984). A prevalence study of enamel defects among young adults in Hong Kong: use of the FDI Index.. New Zealand Dental Journal, 80(360), 47-49.
Scopus7 Europe PMC41984 Bedi, R., & Brook, A. H. (1984). Changes in general, craniofacial and dental development in juvenile hypothyroidism. British Dental Journal, 157(2), 58-60.
Scopus8 WoS4 Europe PMC71983 Brook, A. H., Pitts, N. B., & Renson, C. E. (1983). Determination of tooth dimensions from study casts using an image analysis system.. Journal of the International Association of Dentistry for Children, 14(2), 55-60.
Scopus10 Europe PMC81982 Brook, A. H., & King, N. M. (1982). The role of stainless crowns. Part 1. Properties and techniques.. Dental update, 9(1), 25-28.
Scopus6 Europe PMC21982 Brook, A. H., & King, N. M. (1982). The role of stainless crowns. Part 2. Clinical applications.. Dental update, 9(2), 81-84.
Scopus5 Europe PMC11982 Brook, A. (1982). An Epidemiology Index of Developmental Defects of Dental Enamel (D.D.E. index). International Dental Journal, 32, 159-167. 1981 Brook, A., & King, N. M. (1981). The developing dentition: A Brief Review of the Aetiology of Dental Anomalies and a Preliminary Investigation of Enamel Defects in Hong Kong. Journal of the Hong Kong Society of Community Medicine, 12, 21-29. 1981 Brook, A., & King, N. M. (1981). A Preliminary Study of Enamel Defects in Hong Kong. Scientific Proceedings of the 10th Asian Pacific Dental Congress, 60-63. 1981 Major, E., Winder, M., Brook, A. H., & Berman, D. S. (1981). An evaluation of nitrous oxide in the dental treatment of anxious children. A physiological and clinical study. British Dental Journal, 151(6), 186-191.
Scopus19 WoS16 Europe PMC141980 Brook, A. H., & Ekanayake, N. O. (1980). The etiology of oligodontia: a family history.. ASDC journal of dentistry for children, 47(1), 32-35.
Scopus7 WoS9 Europe PMC31980 HOBKIRK, J. A., & BROOK, A. H. (1980). The management of patients with severe hypodontia. Journal of Oral Rehabilitation, 7(4), 289-298.
Scopus87 WoS75 Europe PMC501979 Brook, A. H., & Winder, M. (1979). Lobodontia--a rare inherited dental anomaly. Report of an affected family. British Dental Journal, 147(8), 213-215.
Scopus8 WoS4 Europe PMC31979 Brook, A. H., Winder, M., Major, E., & Berman, D. S. (1979). Inhalation sedation - an adjunct to improved dental care: Preliminary communication. Journal of the Royal Society of Medicine, 72(10), 756-760.
Scopus2 WoS3 Europe PMC21979 Holt, R. D., & Brook, A. H. (1979). Taurodontism: a criterion for diagnosis and its prevalence in mandibular first permanent molars in a sample of 1,115 British schoolchildren.. Journal of the International Association of Dentistry for Children, 10(2), 41-47.
Scopus18 Europe PMC111979 Brook, A., & Cooke, M. (1979). The Paedodontic/Orthodontic Interface Part 1. Dental Update, 6, 233-245. 1979 Brook, A., & Cooke, M. S. (1979). The Paedodontic/Orthodontic Interface Part 2. Dental Update, 6, 355-365. 1978 Brook, A. H., & Holt, R. D. (1978). The relationship of crown length to root length in permanent maxillary central incisors.. Proceedings of the British Paedodontic Society, 8, 17-20.
Scopus17 Europe PMC111977 Brook, A. H., Duke, S., & Winter, G. B. (1977). Effect on plaque calcium and phosphorus concentration of short exposure to deionised water. Caries Research, 11(4), 243-244.
Scopus1 WoS1 Europe PMC41976 Brook, A. H., & Winter, G. B. (1976). Letter: Idiopathic cervical infections in children.. ASDC journal of dentistry for children, 43(1), 14. 1976 McAllan, L. H., Murray, J. J., Brook, A. H., & Crawford, A. N. (1976). Oral hygiene instruction in children using manual and electric toothbrushes. Benefits after six months. British Dental Journal, 140(2), 51-56.
Scopus6 WoS8 Europe PMC71975 Crawford, A. N., McAllan, L. H., Murray, J. J., & Brook, A. H. (1975). Oral hygiene instruction and motivation in children using manual and electric toothbrushes. Community Dentistry and Oral Epidemiology, 3(6), 257-261.
Scopus19 WoS20 Europe PMC101975 Brook, A. H., & Winter, G. B. (1975). Developmental arrest of permanent tooth germs following pulpal infection of deciduous teeth. British Dental Journal, 139(1), 9-11.
Scopus29 WoS32 Europe PMC191975 Brook, A. H., Gawthorpe, J., & Winter, G. B. (1975). Calcium glycerophosphate and dental plaque. Clinical pilot study. Caries Research, 9(2), 156-162.
Scopus15 WoS17 Europe PMC81975 Winter, G. B., & Brook, A. H. (1975). Enamel hypoplasia and anomalies of the enamel. Dental Clinics of North America, 19(1), 3-24.
Scopus84 WoS81 Europe PMC421975 Brook, A. H. (1975). Variables and criteria in prevalence studies of dental anomalies of number, form and size. Community Dentistry and Oral Epidemiology, 3(6), 288-293.
Scopus32 WoS28 Europe PMC141974 Brook, A. H. (1974). Dental anomalies of number, form and size: their prevalence in British schoolchildren.. Journal of the International Association of Dentistry for Children, 5(2), 37-53.
Scopus234 Europe PMC1391974 Brook, A. H. (1974). The prevalence of dental anomalies in 11-14 year old children: a comparison of continuous and discontinuous residents of a natural fluoride area.. Proceedings of the British Paedodontic Society, 4, 7-12.
Scopus51974 Sandar, K., & Brook, A. H. (1974). A study of children who presented management problems for routine dental treatment.. Journal of the International Association of Dentistry for Children, 5(1), 17-26.
Scopus2 Europe PMC11973 Brook, A. H. (1973). Acute herpetic gingivostomatitis in children.. ASDC journal of dentistry for children, 40(1), 12-18. 1973 Brook, A. H., & Barker, D. K. (1973). The use of deciduous tooth eruption for the estimation of unknown chronological age. Journal of Tropical Pediatrics and Environmental Child Health, 19(2 A), 234-239.
Scopus41973 Brook, A. H. (1973). The secular trend in permanent tooth eruption times. Journal of Tropical Pediatrics and Environmental Child Health, 19(2 A), 206.
Scopus11972 Brook, A. H., & Winter, G. B. (1972). STAPHYLOCOCCAL CERVICO-FACIAL LYMPHADENITIS IN CHILDREN. The Lancet, 300(7778), 660-661.
Scopus9 WoS9 Europe PMC61972 Brook, A. H., & Barker, D. K. (1972). Eruption of teeth among the racial groups of Eastern New Guinea: A correlation of tooth eruption with calendar age. Archives of Oral Biology, 17(4), 751-759.
Scopus13 WoS11 Europe PMC71971 Brook, A. H., Winter, G. B., & Osborne, J. A. (1971). The occurrence of benign cystic lesions of the jaws in children.. Proceedings of the British Paedodontic Society, 1(1), 16-19.
Scopus6 Europe PMC31970 Brook, A. H., & Winter, G. B. (1970). Cervico-facial suppurative lymphadenitis due to staphylococcal infection in childhood. British Journal of Oral Surgery, 8(3), 257-263.
Scopus10 Europe PMC61970 Brook, A. H., & Winter, G. B. (1970). Dental anomalies in association with achondroplasia. Report of two cases. British Dental Journal, 129(11), 519-520.
Scopus5 Europe PMC11970 Brook, A. H., & Winter, G. B. (1970). Double teeth. A retrospective study of 'geminated' and 'fused' teeth in children. British Dental Journal, 129(3), 123-130.
Scopus149 Europe PMC801969 Brook, A. H. (1969). Recurrent parotitis in childhood.. British dental journal, 127(6), 271-275.
Scopus10 Europe PMC4- Scriven, G., Roger, J., Brook, A., Scott, G. R., Mihailidis, S., Bin Khamis, M. F., & Townsend, G. (n.d.). Frequency of Occurrence and Degree of Expression of the Parastyle in Several Modern Human Populations. Dental Anthropology Journal, 31(1), 3-9.
- Brook, A. H., & Scheers, M. (n.d.). Variations of Tooth Root Morphology in a Romano- British Population. Dental Anthropology Journal, 19(2), 33-38.
- Brook, A. H. (n.d.). "Dental Arch Dimensions in a Matched Pairs Study of Hypodontia Patients and Controls". Biomedical Journal of Scientific & Technical Research, 41(1).
- Shah, A. A., Elcock, C., & Brook, A. H. (n.d.). Posterior tooth morphology and lower incisor crowding. Dental Anthropology Journal, 18(2), 37-42.
- Brook, A. H., Underhill, C., Foo, L. K., & Hector, M. (n.d.). Approximal Attrition and Permanent Tooth Crown Size in a Romano-British Population. Dental Anthropology Journal, 19(1), 23-28.
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Books
Year Citation 2009 Brook, A. (2009). Clinical aspects of dental morphology: An introduction (Vol. 13). T. Koppe (Ed.), KARGER.
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Book Chapters
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Conference Papers
Year Citation 2017 Taduran, R., Ranjitkar, S., Hughes, T., Townsend, G., & Brook, A. (2017). Complex systems in human dental development: sexual dimorphism in teeth and fingerprints of Australian twins. In G. Rzveski, & C. Brebbia (Eds.), Complex Systems: Theory and Applications (pp. 194-203). United Kingdom: WIT Press. 2016 Brook, A., Liversidge, H., Wilson, D., Jordan, Z., Harvey, G., Marshall, R., & Kitson, A. (2016). Health research, teaching and provision of care: Applying a new approach based on complex systems and a knowledge translation complexity network model. In C. A. Brebbia, & G. Rzveski (Eds.), Proceedings of the New Forest Conference on Complex Systems 2016, as published in International Journal of Design and Nature and Ecodynamics Vol. 11 (pp. 663-669). online: WIT Press.
Scopus42016 Koh, K., Toh, V., O'donnell, M., Ranjitkar, S., & Brook, A. (2016). A complex adaptive system in which environmental stress affects gene expression during development. In C. A. Brebbia, & G. Rzveski (Eds.), International Journal of Design and Nature and Ecodynamics Vol. 11 (pp. 686-695). online: WIT Press.
Scopus32011 Brook, A., & O'Donnell, M. (2011). The dentition: A complex system demonstrating self-* principles. In Proceedings of SASO 2011 (pp. 208-209). USA: IEEE.
Scopus82009 Smith, R., Townsend, G., Chen, K., & Brook, A. (2009). Synetic superimposition of dental 3D data: Application in Twin Studies. In Frontiers of Oral Biology Vol. 13 (pp. 142-147). Postfach Basel Switzerland CH-4009: Karger.
Scopus4 WoS3 Europe PMC32009 Townsend, G., Hughes, T., Bockmann, M., Smith, R., & Brook, A. (2009). How studies of twins can inform our understanding of dental morphology.. In Frontiers of Oral Biology Vol. 13 (pp. 136-141). Postfach Basel Switzerland CH-4009: Karger.
Scopus14 WoS10 Europe PMC72009 Townsend, G., Harris, E., Lesot, H., Clauss, F., & Brook, A. (2009). Morphogenetic fields within the human dentition: a new, clinically relevant synthesis of an old concept. In Proceedings of the International Workshop on Oral Growth and Development Vol. 54 (pp. S34-S44). The Boulevard Langford Lane Kidlington Oxford England OX5 1GB: Pergamon-Elsevier Science Ltd.
Scopus83 WoS67 Europe PMC382009 Horrocks, L. R., Brook, A., Alvesalo, L., & Smith, R. N. (2009). A three-dimensional comparison of the modifying effects of familial genetic contribution in turner syndrome. In T. Koppe (Ed.), Frontiers of Oral Biology Vol. 13 (pp. 148-152). Greifswald, GERMANY: KARGER.
Scopus2 WoS1 Europe PMC12006 Brook, A. H., & Smith, J. M. (2006). Hypoplastic enamel defects and environmental stress in a homogeneous Romano-British population. In European Journal of Oral Sciences Vol. 114 (pp. 370-374). Brewster, MA: WILEY.
Scopus5 WoS5 Europe PMC52006 Elcock, C., Smith, R. N., Simpson, J., Abdellatif, A., Bäckman, B., & Brook, A. H. (2006). Comparison of methods for measurement of hypoplastic lesions. In European Journal of Oral Sciences Vol. 114 (pp. 365-369). Brewster, MA: WILEY.
Scopus10 WoS8 Europe PMC62006 Elcock, C., Lath, D. L., Luty, J. D., Gallagher, M. G., Abdellatif, A., Bäckman, B., & Brook, A. H. (2006). The new Enamel Defects Index: Testing and expansion. In European Journal of Oral Sciences Vol. 114 (pp. 35-38). Brewster, MA: WILEY.
Scopus21 WoS20 Europe PMC132005 Khalaf, K., Elcock, C., Smith, R. N., & Brook, A. H. (2005). Fluctuating dental asymmetry of multiple crown variables measured by an image analysis system. In Archives of Oral Biology Vol. 50 (pp. 249-253). York, ENGLAND: PERGAMON-ELSEVIER SCIENCE LTD.
Scopus18 WoS20 Europe PMC12 -
Conference Items
Year Citation 2023 Hughes, T., Suresh, S., Bockmann, M., Davis, K., & Brook, A. (2023). Long lost cousins or distant neighbours? The dental morphology of early South-East Asian migration. Poster session presented at the meeting of AMERICAN JOURNAL OF BIOLOGICAL ANTHROPOLOGY. WILEY. 2023 McCrary, T., Paul, K., Hughes, T., & Brook, A. (2023). A test of identical twin mirroring in the dentition. Poster session presented at the meeting of 92nd Annual Meeting of the American Association of Biological Anthropology. 2022 Brook, A., Sassani, S., Hughes, T., O'Donnell, M. B., Ranjitkar, S., Higgins, D., . . . Henneberg, M. (2022). 3D measurement of permanent tooth crowns in hypodontia and controls. Poster session presented at the meeting of International Association of Dental Research, 100th General Session and Exhibition. 2016 Hughes, T. E., Townsend, G. C., Brook, A. H., Bockmann, M. R., & Mihailidis, S. (2016). The modern human dentition: insights from three decades of studies on twins. Poster session presented at the meeting of AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY. Atlanta, GA: WILEY-BLACKWELL. 2013 Brook, A. H., Hughes, T., Townsend, G. C., & O'Donnell, M. D. B. (2013). The development of the dentition as a complex adaptive system. Poster session presented at the meeting of Program of the 82nd Annual Meeting of the American Association of Physical Anthropologists, as published in American Journal of Physical Anthropology. Knoxville, TN: Wiley-Blackwell.
Funding - current application
- Paul Kwok Lee Research Funding Bequest - "Development and application of customised software for 3D measurements of human teeth and dental arches"
Research Funding Awarded:
- 1970-73 "The aetiology of dental anomalies" - Eastman Research Fund - £12,000
- 1973-74 "The role of calcium glycerophosphate in remineralisation" - with G. B. Winter Beechams Ltd - £5,000
- 1978-80 "The prevalence and aetiology of enamel defects in school children in London"- Dental-Eze Ltd - £15,000
- 1980-83 "The use of image analysis to measure tooth dimensions on study models and dental caries on radiographs" - With C. E. Renson and N. B. Pitts, Hong Kong University - £75,000
- 1982-83 "A multi-disciplinary study of the dental and oral tissues of 12 year old Hong Kong children" - Hong Kong University - £38,000
- 1983 "Dental care of the handicapped in Hong Kong" - Colgate Palmolive Plc - £2,000
- 1987-89 "Clinical trials of anti-plaque and hypersensitivity agents for use in dental products"- Boots Plc - £12,000
- 1989-91 "Development of x-ray microtomography for the 3D measurement of mineralisation in genetic defects and carious lesions" - With J. C. Elliott, The London Hospital Special Trustees - £17,500
- 1992 "Clinical trials of anti-plaque agents" - Boots Plc - £15,000
- 1993-94 "Clinical trials of anti-plaque agents" - Boots Plc - £20,000
- 1993 "A study of the demineralising and remineralising potential of agents used in mouthwashes" - With P. Anderson, Boots Plc - £7,500
- 1994 "The use of image analysis for diagnosis of the extent of plaque" - With G. Davis, Boots Plc - £11,000
- 1995 "Clinical studies of anti-plaque and stain removing agents" - Boots Plc - £10,000
- 1995 "The measurement of tooth size in hypodontia" - With G. Davis and J. Fearne, Bone, Tooth and Biomaterials Research Group, LHMC - £371
- 1995 "A study of the demineralising and remineralising potential of a tooth whitening agent" - With J. C. Elliott and P. Anderson, Boots Plc - £7,200
- 1995-96 "Development of Software to enable a scanning data entry method for the national outpatient audit computer package" - With T. Gregg and F. Wong, Department of Health - £5,650
- 1995-97 "Collaborative research in the development of new dental products" - With M. Levinkind and J. Elliot, Proctor and Gamble Plc - £200,000
- 1997 Sheffield study to determine the anti-plaque efficacy of Boots new formulation (toothpaste) - With T. F. Walsh, Boots Plc - £33,600
- 1997 "Further development of an image analysis systems for dental measurement" - Boots Plc - £6,750
- 1997 "Dental Occlusion - a laboratory study of potential de-sensitising agents" - With R. van Noort, Boots Plc - £7,500
- 1997 "A Single Dose Study to Evaluate the Safety and Efficacy of 4% Articaine HCl with 1:100,000 Epinephrine Versus 2% Lidocaine HCl with 1:100,000 Epinephrine in the Treatment of General Dental Procedures - Spécialitiés Septodont - £2,500
- 1997 Tooth Whitening Clinical Trial- With T. F. Walsh and A. Rawlinson, Boots plc - £20,000
- 1997 Plaque Inhibition - With T. F. Walsh and A. Rawlinson, Boots plc - £15,000
- 1997 Plaque Inhibition - With T. F. Walsh and A. Rawlinson, Boots plc - £36,000
- 1999-2004 National Centre for Applied Research in Oral Health - Boots plc - Direct financial contribution
- (Total value of Centre over 5 years including salaries of seconded Boots staff) - £667,000 (£1,250,000)
- 1999 A multi-detection microplate reader for the rapid analysis of disease processes and biomaterials
- BBSRC JREI Grant (50/JE514370) - £29,952
- 1999 Computer controlled X-Y translation stage with 1 micro repositioning accuracy in both directions and a digital spectometric X-ray detection system - With P. Anderson et al, Queen Mary and Westfield College
- Wellcome Grant (062850/Z) - $32,629
- 2001 Development and testing of a strategy for educating the dental team together in community settings
- National Purchasing Unit - £30,000
- 2002 Training the dental team together in other primary care settings - National Dental Development Unit - £598,000
- 2002 The genetics of hypodontia - With P. Patel, C. Elcock, National Institute of Health (USA) - £15,000 (Total value of grant $1,000,000)
- 2005 Odontogenesis: A paradigm for mammalian biomineralisation and the role of extracellular matrix in the control of crystal deposition and growth - With J. Kirkham, Leeds and M. Dixon, Manchester, Wellcome 5 Year Programme Grant - £950,000 (Personal component £178,000)
- 2005 The measurement of anti-calculus effect - With A. Rawlinson and T. Walsh, Boots plc - £13,000
- 2006 The Measurement of Tooth Whiteness, using image Analysis - Development of methodology - With R. N. Smith, Unilever plc - £35,000
- 2006 The Measurement of Tooth Whiteness using Image Analysis - Clinical trial Unilever plc - £20,000
- 2006 Evaluation of methods of measurement of tooth colour - Unilever plc - £5,000
- 2007 Normal and Abnormal Development of the Dentition - University of Adelaide - AU$4,560
- 2008 The measurement of dental anomalies in twins - University of Adelaide - AU$5,220
- 2008 3D tooth dimensions on study models of twins - University of Adelaide - AU$2,378
- 2008 Fluoride concentrations in toothpastes used by children. - Boots plc - £8,000
- 2008 The effect of prenatal exposure to anticonvulsant drugs measured by variations in Dental Development: A pilot study. - With S. Albadri and G. Baker, University of Liverpool - £1,500
- 2009 Are dental crown dimensions increased in females from opposite sex dizygotic twin pairs reflecting possible male hormone diffusion in utero? - With D. Ribeiro, G. Townsend, W. Sampson, T. Hughes, A. H. Brook - ADRF Grant No 26-2009 - AU$2,800
- 2013- 2017 Improving the appearance and mineralisation of lesions in deciduous teeth - With P. Anderson, BBSRC/GSK Case Study- Ph.D. Studentship - £100,000
- 2013-2015 State-of-the-art imaging of early enamel lesions - With A. Diep, S. Ranjitkar, J. Kaidonis and G. Townsend, Dentsply Research Fund - AU$850
- 2013-2014 High resolution 3D dental microwear texture analysis - With C. Mann, S. Ranjitkar, J. Kaidonis, D. Lekkas and G. Townsend, Dentsply Research Fund - AU$850
- 2013-2015 Exploring further the different effects of the Y chromosome and intrauterine male hormones on tooth size and shape by 3D measurement and analysis of twin study models - With F. Lam, S. Ranjitkar, T. Hughes and G. Townsend, ADRF - AU$2,900
- 2014 Imaging of early enamel erosion in deciduous teeth - With C. Mann, S. Ranjitkar, C. Hall and D. Lekkas, ADRF - AU$7,660
- 2014 Effects of Y chromosome and male hormones on tooth size - With F. Lam, G. Townsend, S. Ranjitkar, T. Hughes and R. Yong, ADRF - AU$2,200
- 2014 Dental microwear texture analysis using state-of-the-art imaging. - With C. Mann, S. Ranjitkar, J. Kaidonis, D. Lekkas and G. Townsend, ADRF - AU$2,200
- 2014-15 Environmental stress and the Romano-British Dentition - With K. Koh, ADRF - AU$2,200
- 2014-15 Effects of Y chromosome and intrauterine male hormones on primary tooth size - With A. Ahmed, ADRF - AU$1,200
- 2014-15 Dental asymmetry in twins: the link between tooth dimensions and tooth development - With R. Yong, S. Ranjitkar, A. Evans, G.C. Townsend, ADRF - AU$7,700
- 2015 MIMICS software for 3D CT and microCT image analysis in craniofacial research - ADRF - AU$4,000
- 2020 Large volume Micro-CT for the study of archeological skull specimens - University of Adelaide - AU$5000
- 2020 3D measurement using a new technique of teeth and dental arches in hypodontia and control patients - Paul Kwok Lee Bequest - AU$37,000
Supervision - current students
- Ph.D. (joint supervision) - " An investigation of dental and skeletal health parameters in a sample of 19th -century migrant settlers to South Australia" - A. Gurr
- Ph.D. (joint supervision) - "The longitudinal development of the dental arcahes in the primary and permanent dentiton of twins" - J. Giri
- Ph.D (joint supervision) - " The effect of chemotherapeutic agents on dental development and the oral mucosa" - S. Al-Ansari
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2022 Co-Supervisor A longitudinal study of the development of dental occlusion and facial profiles of monozygotic and dizygotic Australian twins, from the primary to the permanent dentition. Doctor of Philosophy Doctorate Full Time Mr Jamal Giri -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2019 - 2023 Co-Supervisor A view of colonial life in South Australia: An osteological investigation of the health status among 19th-century migrant settlers Doctor of Philosophy Doctorate Part Time Mrs Angela Gurr 2016 - 2018 Principal Supervisor Tooth crown dimensions and cusp number in hypodontia: assessed by a new three-dimensional technique Master of Philosophy (Dentistry) Master Part Time Miss Sadaf Sassani 2014 - 2018 Principal Supervisor The Nature and Extent of Sexual Dimorphism in Dental and Dermatoglyphic Traits of Twins Doctor of Philosophy Doctorate Full Time Mr Richard Jonathan Ordonez Taduran 2012 - 2013 Co-Supervisor Infraocclusion of Primary Molars and Associated Dental Anomalies in Twins and Singletons: What is the Underlying Aetiology? Doctor of Philosophy Doctorate Full Time Dr Ruba Mohammad Mousa Odeh 2008 - 2012 External Supervisor Increased Tooth Crown Size in Females from Opposite-Sex Dizygotic Twins: A Possible Intrauterine Hormonal Influence on Dental Development Doctor of Philosophy Doctorate Full Time Mrs Daniela Cisoto Ribeiro -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2022 - ongoing Co-Supervisor The effect of chemotherapeutic agents on dental development and the oral mucosa Adelaide Dental School - Doctorate Full Time S. Al-Ansari 2019 - ongoing Co-Supervisor "The longitudinal development of the dental arcahes in the primary and permanent dentiton of twins" Adelaide Dental School - Doctorate Full Time J.Giri 2014 - 2016 Co-Supervisor The effects of the Y chromosome and intrauterine male hormones on human tooth size and shape The University of Adelaide - Honours Part Time Felicity Lam
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