Tongzhi Wu

Research Interests

Clinical Trials Endocrinology & Metabolism Medical Biochemistry: Proteins and Peptides Medical Physiology Nutrition and Metabolic Health Translational Health Outcomes

APrf Tongzhi Wu

Int Grant-Funded Researcher D

School of Medicine

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

A/Prof Wu is an emerging research leader, with a steeply rising trajectory in research on nutrient-gut interactions and type 2 diabetes. He was a top medical graduate (2009) of Southeast University (Nanjing, China), completed a University of Adelaide PhD conferred with a University Doctoral Research Medal (2013), and transformed into a research group leader during his Royal Adelaide Hospital (RAH) Mary Overton Early Career (2015-17) and Flory (2018-20) Fellowships. He was awarded a ‘top-ranked’ Mid-Career Fellowship from The Hospital Research Foundation (THRF) in 2020 and was promoted to “Associate Professor” by the University of Adelaide in 2021.

Type 2 diabetes is now a "global pandemic", and is a leading cause of blindness, amputations, heart disease and kidney disease. Early detection of individuals at risk, and achieving good glycaemic control in those with type 2 diabetes, are key to improving health outcomes and reducing costs. The gut (stomach and intestines) is central to the control of blood glucose and appetite, and therefore represents a logical, yet relatively unexplored, target for novel and improved treatments for type 2 diabetes. A/Prof Wu's program focuses on the pivotal role of the gastrointestinal (GI) tract in glucose metabolism, aiming to understand the pathophysiology, and establish novel strategies to mitigate the risk of type 2 diabetes. This work has achieved international recognition by establishing: (i) key pathological features of GI function responsible for elevated blood glucose in type 2 diabetes, (ii) marked variations in gut-mediated glucose responses along the length of the GI tract, (iii) the predominance of the incretin hormone, glucagon-like peptide-1 (GLP-1), over other gut peptides, in mediating these actions, and (iv) the substantial potential for stimulating endogenous GLP-1 to optimise glycaemic control in patients with type 2 diabetes. A/Prof Wu has co-authored >100 peer-reviewed publications in the top-tier journals, featuring predominantly in the leading journals in the field of diabetes (e.g. Diabetes, Diabetes Care, Diabetes Obes Metab), nutrition (e.g. Am J Clin Nutr) and Endocrinology (e.g. JCEM). 

With ongoing funding support from the NHMRC, Diabetes Australia, The Hospital Research Foundation, Royal Adelaide Hospital Research Committee and The University of Adelaide, his team is determining: (i) the roles of bitter taste sensing pathways in different regions of the gut in the regulation of gastrointestinal function, energy intake and postprandial glycaemia, (ii) the potential of utilising bile acids as a therapy to restore glucose homeostasis and measuring circulating bile acid profiles to predict future risk of type 2 diabetes, and (iii) the clinical efficacy of combining a dietary strategy with pharmacotherapy on glycaemic control. These studies have a high potential to establish novel, safe and cost-effective solutions to type 2 diabetes. In this effort, he has also built novel research platforms (i.e. organ-on-a-chip) in collaboration with Prof Heike Ebendorff-Heidepriem and Dr Tim Zhao to markedly enhance the capability for investigating the mechanisms by which intraluminal contents interact with the gut and for screening effective therapeutic regimen for evaluation in clinical trials.

 

PATENTS:

1. Patent Title: METHODS AND COMPOSITION FOR TREATING METABOLIC DISORDERS AND HYPERGLYCAEMIA

Patent Number: AU 2023900718 (Inventors: Tongzhi Wu, Chris Rayner, Richard Young, Chunjie Xiang, Cong Xie, Michael Horowitz, Karen Jones)

2. Patent Title: METHODS AND COMPOSITION FOR PREVENTING AND/OR TREATING DIABETES ASSOCIATED WITH LOW-CALORIE SWEETENERS

Patent Number: AU 2023901506 (Inventors: Tongzhi Wu, Chris Rayner, Richard Young, Tingting Li, Cong Xie, Weikun Huang, Michael Horowitz, Karen Jones)

 

PUBLICATIONS:

Original articles

  1. Wu T, Zhao BR, Bound MJ, Checklin HL, Bellon M, Little TJ, Young RL, Jones KL, Horowitz M, Rayner CK. Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycaemia in healthy humans. Am J Clin Nutr. 2012;95:78-83.
  2. Wu T, Bound MJ, Standfield SD, Jones KL, Horowitz M, Rayner CK. Effects of taurocholic acid on glycaemic, glucagon-like Peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans. J Clin Endocrinol Metab. 2013;98:E718-22. 
  3. Wu T, Bound MJ, Standfield SD, Gedulin B, Jones KL, Horowitz M, Rayner CK. Effects of rectal administration of taurocholic acid on glucagon-like peptide-1 and peptide YY secretion in healthy humans. Diabetes Obes Metab.2013;15:474-7.
  4. Wu T, Bound MJ, Zhao BR, Standfield SD, Bellon M, Jones KL, Horowitz M, Rayner CK. Effects of a D-xylose preload with or without sitagliptin on gastric emptying, glucagon-like peptide-1, and postprandial glycaemia in type 2 diabetes. Diabetes Care. 2013;36:1913-8.
  5. Chang J, Wu T, Greenfield JR, Samocha-Bonet D, Horowitz M, Rayner CK. Effects of intraduodenal glutamine on incretin hormone and insulin release, the glycemic response to an intraduodenal glucose infusion and antropyloroduodenal motility in health and type 2 diabetes. Diabetes Care. 2013;36:2262-5.
  6. Young RL, Chia B, Isaacs NJ, Ma J, Khoo J, Wu T, Horowitz M, Rayner CK. Disordered control of intestinal sweet taste receptor expression in type 2 diabetes. Diabetes. 2013;62:3532-41.
  7. Wu T, Bound MJ, Standfield SD, Bellon M, Young RL, Jones KL, Horowitz M, Rayner CK. Artificial sweeteners have no effect on gastric emptying, glucagon-like peptide-1, or glycaemia in healthy humans. Diabetes Care. 2013;36:e202-3.
  8. Li F, Chen B, Li L, Zha M, Zhou S, Wu T, Bachem MG, Sun Z. INS-1 cells inhibit the production of extracellular matrix from pancreatic stellate cells. J Mol Histol. 2014;45:321-7.
  9. Wu T, Ma J, Bound MJ, Checklin H, Deacon CF, Jones KL, Horowitz M, Rayner CK. Effects of sitagliptin on glycaemia, incretin hormones, and antropyloroduodenal motility in response to intraduodenal glucose infusion in healthy lean and obese humans, and patients with type 2 diabetes treated with or without metformin. Diabetes. 2014;63:2776-87.
  10. Wu T, Thazhath SS, Bound MJ, Jones KL, Horowitz M, Rayner CK. Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity? Diabetes Res Clin Pract. 2014;106:e3-6.
  11. Thazhath SS, Wu T, Bound MJ, Checklin HL, Jones KL, Willoughby S, Horowitz M, Rayner CK. Changes in meal composition and duration affect postprandial endothelial function in healthy humans. Am J Physiol GastrointestLiver Physiol. 2014;307:G1191-7.
  12. Wu T, Trahair LG, Bound MJ, Deacon CF, Horowitz M, Jones KL, Rayner CK. Effects of sitagliptin on blood pressure and heart rate in response to intraduodenal glucose infusion in patients with type 2 diabetes. Diabet Med.2015;32:595-600.
  13. Wu T, Thazhath SS, Marathe CS, Bound MJ, Jones KL, Horowitz M, Rayner CK. Comparative effect of intraduodenal and intrajejunal infusion on the gut-incretin axis response in healthy males. Nutr Diabetes.2015;5:e156.
  14. Yang BQ, Lu Y, He JJ, Wu TZ, Xie ZL, Lei CH, Zhou Y, Han J, Bian MQ, You H, Mei DX, Sun ZL. Performance of Fasting Plasma Glucose and Postprandial Urine Glucose in Screening for Diabetes in Chinese High-risk Population. Chin Med J. 2015;128:3270-3275.
  15. Zhang X, Liu T, Wang Y, Zhong M, Zhang G, Liu S, Wu T, Rayner CK, Hu S. Comparative Effects of Bile Diversion and Duodenal-Jejunal Bypass on Glucose and Lipid Metabolism in Male Diabetic Rats. Obes Surg. 2016;26:1565-75.
  16. Thazhath SS, Wu T, Bound MJ, Checklin HL, Standfield S, Jones KL, Horowitz M, Rayner CK. Administration of resveratrol for 5 wk has no effect on glucagon-like peptide 1 secretion, gastric emptying, or glycemic control in type 2 diabetes: a randomized controlled trial. Am J Clin Nutr. 2016;103:66-70.
  17. Thazhath SS, Marathe CS, Wu T, Chang J, Khoo J, Kuo P, Checklin HL, Bound MJ, Rigda RS, Crouch B, Jones KL, Horowitz M, Rayner CK. The Glucagon-Like Peptide 1 Receptor Agonist Exenatide Inhibits Small Intestinal Motility, Flow, Transit, and Absorption of Glucose in Healthy Subjects and Patients With Type 2 Diabetes: A Randomized Controlled Trial. Diabetes. 2016;65:269-75.
  18. Wu T, Little TJ, Bound MJ, Borg M, Zhang X, Deacon CF, Horowitz M, Jones KL, Rayner CK. A Protein Preload Enhances the Glucose-Lowering Efficacy of Vildagliptin in Type 2 Diabetes. Diabetes Care. 2016;39:511-7.
  19. Thazhath SS, Wu T, Bound MJ, Checklin HL, Standfield S, Jones KL, Horowitz M, Rayner CK. Effects of intraduodenal hydroxycitrate on glucose absorption, incretin release, and glycemia in response to intraduodenal glucose infusion in health and type 2 diabetes: A randomised controlled trial. Nutrition. 2016;32:553-9.
  20. Chen C, Hu B, Wu T, Zhang Y, Xu Y, Feng Y, Jiang H. Bile acid profiles in diabetic (db/db) mice and their wild type littermates. J Pharm Biomed Anal. 2016;131:473-481.
  21. Wu T, Zhang X, Trahair LG, Bound BM, Little TJ, Deacon CF, Horowitz M, Jones KL, Rayner CK. Small intestinal glucose delivery affects the lowering of blood glucose by acute vildagliptin in type 2 diabetes. J Clin Endocrinol Metab. 2016;101:4769-4778.
  22. Rigda RS, Trahair LG, Little TJ, Wu T, Standfield SD, Feinle-Bisset C, Rayner CK, Horowitz M, Jones KL. Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects. Peptides.2016;86:126-132.
  23. Thazhath SS, Marathe CS, Wu T, Chang J, Khoo J, Kuo P, Checklin HL, Bound MJ, Rigda RS, Crouch B, Jones KL, Horowitz M, Rayner CK. Acute effects of the glucagon-like peptide-1 receptor agonist, exenatide, on blood pressure and heart rate responses to intraduodenal glucose infusion in type 2 diabetes. Diabetes Vasc Dis Res. 2017;14:59-63.
  24. Wu T, Xie C, Wu H, Horowitz M, Jones KL, Rayner CK. Metformin reduces the rate of small intestinal glucose absorption in type 2 diabetes. Diabetes Obes Metab. 2017;19:290-93.
  25. Wu T, Trahair LG, Little TJ, Bound MJ, Zhang X, Wu H, Sun Z, Horowitz M, Rayner CK, Jones KL. Effects of vildagliptin and metformin on blood pressure and heart rate responses to small intestinal glucose in type 2 diabetes. Diabetes Care. 2017;40:702-5.
  26. Wu T, Rayner CK, Watson LE, Jones KL, Horowitz M, Litter TJ. Comparative Effects of intraduodenal fat and glucose on the gut-incretin axis in healthy males. Peptides. 2017;95:124-127.
  27. Trahair LG, Wu T, Feinle-Bisset C, Marathe CS, Rayner CK, Horowitz M, Jones KL. Comparative effects of small intestinal glucose on blood pressure, heart rate and noradrenaline responses in obese, and healthy, subjects. Physiol Rep. 2018;6(4). doi: 10.14814/phy2.13610.
  28. Rigda RS, Trahair LG, Wu T, Little TJ, Lange K, Feinle-Bisset C, Rayner CK, Horowitz M, Jones KL. Effects of length and region of small intestine exposed to glucose on blood pressure, superior mesenteric artery blood flow and plasma noradrenaline in healthy older subjects. J Aging Res Clin Practice. 2018;7:149-155.
  29. Young RL, Lumsden AL, Martin AM, Schober G, Pezos N, Thazhath SS, Isaacs NJ, Cvijanovic N, Sun EWL, Wu T, Rayner CK, Nguyen NQ, Fontgalland D, Rabbitt P, Hollington P, Sposato L, Due SL, Wattchow DA, Liou AP, Jackson VM, Keating DJ. Augmented capacity for peripheral serotonin release in human obesity. Int J Obes. 2018;42(11):1880-9. 
  30. Pham HT, Stevens JE, Rigda RS, Phillips LK, Wu T, Hausken T, Soenen S, Visvanathan R, Rayner CK, Horowitz M, Jones KL. Effects of intraduodenal administration of the artificial sweetener, sucralose, on blood pressure and superior mesenteric artery blood flow in healthy older subjects. Am J Clin Nutr. 2018;108(1):156-162.
  31. Veedfald S, Wu T, Bound M, Grivell J, Hartmann B, Rehfeld JF, Deacon CF, Horowitz M, Holst JJ, Rayner CK. Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men. J Clin Endocrinol Metab. 2018;103(12):4409-18. 
  32. Borg MJ, Bound M, Grivell J, Sun Z, Jones KL, Horowitz M, Rayner CK, Wu T. Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes. Diabetes Obes Metab. 2019;21(3):640-647.
  33. Borg MJ, Jones KL, Sun Z, Horowitz M, Rayner CK, Wu T. Metformin attenuates the postprandial fall in blood pressure in type 2 diabetes. Diabetes Obes Metab. 2019;21(5):1251-1254.
  34. Jones KL, Rigda RS, Buttfield MDM, Hatzinikolas S, Pham HT, Marathe CS, Wu T, Lange K, Trahair LG, Rayner CK, Horowitz M. Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycemia in health and type 2 diabetes. Diabetes Obes Metab. 2019;21(5):1158-1167.
  35. Zhang X, Young RL, Bound M, Hu S, Jones KL, Horowitz M, Rayner CK, Wu T.  Comparative effects of proximal and distal small intestinal glucose exposure on glycemia, incretin hormone secretion and the incretin effect in health and type 2 diabetes. Diabetes Care. 2019;42(4):520-528.
  36. Shi R, Wang Y, An X, Ma J, Wu T, Yu X, Liu S, Huang L, Wang L, Liu J, Ge J, Qiu S, Yin H, Wang X, Wang Y, Yang B, Yu J, Sun Z. Efficacy of Co-administration of Liuwei Dihuang Pills and Ginkgo Biloba Tablets on Albuminuria in Type 2 Diabetes: A 24-Month, Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial. Front Endocrinol. 2019 Feb 22;10:100.
  37. Watson LE, Phillips LK, Wu T, Bound MJ, Checklin HL, Grivell J, Jones KL, Clifton PM, Horowitz M, Rayner CK. A whey/guar "preload" improves postprandial glycaemia and HbA1c in type 2 diabetes - a 12-week, single-blind, randomized, placebo-controlled trial. Diabetes Obes Metab. 2019 Apr;21(4):930-938
  38. Watson LE, Phillips LK, Wu T, Bound MJ, Checklin HL, Grivell J, Jones KL, Horowitz M, Rayner CK. Differentiating the effects of whey protein and guar gum preloads on postprandial glycemia in type 2 diabetes. Clin Nutr. 2019 Dec;38(6):2827-2832.
  39. Watson LE, Xie C, Wang X, Li Z, Phillips LK, Sun Z, Jones KL, Horowitz M, Rayner CK, Wu T. Gastric emptying in patients with well-controlled type 2 diabetes compared to non-diabetic young and older controls. J Clin Endocrinol Metab. 2019 Aug 1;104(8):3311-3319.
  40. Bitarafan V, Fitzgerald PCE, Little TJ, Meyerhof W, Wu T, Horowitz M, Feinle-Bisset C. Intraduodenal infusion of the bitter tastant, quinine, does not modulate antropyloroduodenal motility, plasma cholecystokinin or energy intake in healthy men. J Neurogastroenterol Motil. 2019 Jul 1;25(3):413-422.
  41. Watson LE, Phillips LK, Wu T, Bound MJ, Jones KL, Horowitz M, Rayner CK. Longitudinal evaluation of gastric emptying in type 2 diabetes. Diabetes Res Clin Pract. 2019 Aug;154:27-34.
  42. Pham H, Holen IS, Phillips LK, Hatzinikolas S, Huynh LQ, Wu T, Hausken T, Rayner CK, Horowitz M, Jones KL.The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects. Nutrients. 2019 Nov 5;11(11). pii: E2666.
  43. Pham H, Marathe CS, Phillips LK, Trahair LG, Hatzinikolas S, Huynh L, Wu T, Nauck M, Rayner CK, Horowtiz M, Jones KL. Longitudinal changes in fasting and glucose-stimulated GLP-1 and GIP in healthy older subjects. J Clin Endocrinol Metab. 2019 Dec 1;104(12):6201-6206.
  44. Stevens JE, Buttfield M, Wu T, Hatzinikolas S, Pham H, Lange K, Rayner CK, Horowitz M, Jones CK. Effects of sitagliptin on gastric emptying of, and the glycaemic and blood pressure responses to, a carbohydrate meal in type 2 diabetes. Diabetes Obes Metab. 2020 Jan;22(1):51-58.
  45. Wang X, Xie C, Marathe CS, Malbert CH, Horowitz M, Jones KL, Rayner CK, Sun Z, Wu T. Disparities in gastric emptying and postprandial glycaemia between Han Chinese and Caucasians with type 2 diabetes. Diabetes Res Clin Pract. 2020 Jan;159:107951
  46. Bitarafan V, Fitzgerald PCE, Little TJ, Meyerhof W, Jones KL, Wu T, Horowitz M, Feinle-Bisset C. Intragastric administration of the bitter tastant quinine lowers the glycemic response to a nutrient drink without slowing gastric emptying in healthy men. Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R263-R273.
  47. Huang W, Wu T*, Shallan A, Kostecki R, Rayner CK, Priest C, Ebendorff-Heidepriem H, Zhao J* (*joint senior authorship). A Multiplexed Microfluidic Platform toward Interrogating Endocrine Function: Simultaneous Sensing of Extracellular Ca2+ and Hormone. ACS Sens. 2020 Feb 28;5(2):490-499
  48. Xie C, Wang X, Jones KL, Horowitz M, Sun Z, Little TJ, Rayner CK, Wu T. Role of endogenous glucagon-like peptide-1 enhanced by vildagliptin in the glycaemic and energy expenditure responses to intraduodenal fat infusion in type 2 diabetes. Diabetes Obes Metab. 2020 Mar;22(3):383-392.
  49. Jones KL, Huynh LQ, Hatzinikolas S, Rigda RS, Phillips LK, Pham HT, Marathe CS, Wu T, Malbert CH, Stevens JE, Lange K, Rayner CK, Horowitz M. Exenatide once weekly slows gastric emptying of solids and liquids in healthy, overweight people at steady-state concentrations. Diabetes Obes Metab. 2020 May;22(5):788-797
  50. Marathe CS, Pham H, Marathe JA, Trahair LG, Huynh L, Wu T, Phillips LK, Rayner CK, Nauck MA, Horowitz M, Jones KL. The relationship between plasma GIP and GLP-1 levels in individuals with normal and impaired glucose tolerance. Acta Diabetol. 2020 May;57(5):583-587
  51. Qiu S, Cai X, Wu T, Sun Z, Guo H, Kirsten J, Wendt J, Steinacker JM, and Schumann U. Objectively-measured light-intensity physical activity and risk of cancer mortality: a meta-analysis of prospective cohort studies. Cancer Epidemiol Biomarkers Prev. 2020 May;29(5):1067-1073
  52. Rayner CK, Watson LE, Phillips LK, Lange K, Bound MJ, Grivell J, Wu T, Jones KL, Horowitz M, Ferrannini E, Trico D, Frascerra Mari A, Natali A. Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: a randomized controlled trial. Diabetes Care. 2020 Aug;43(8):1813-1821
  53. Zhang X, Jones KL, Horowitz M, Rayner CK, Wu T. Effects of proximal and distal enteral glucose infusion on cardiovascular response in health and type 2 diabetes. J Clin Endo Metab. 2020 Aug 1;105(8):dgaa341
  54. Qiu S, Cai X, Jia L, Sun Z, Wu T, Wendt J, Steinacker JM, Schumann U. Does objectively-measured light-intensitity physical activity reduce the risk of cardiovascular mortality? A Meta-analysis. Eur Heart J Qual Care Clin Outcomes 2020 Jun 8:qcaa051
  55. Jalleh R, Pham H, Marathe CS, Wu T, Buttfield M, Hatzinikaloas S, Malbert CH, Rigda R, Lange K, Trahair L, Feinle-Bisset C, Rayner CK, Horowitz M, Jones KL. Acute effects of lixisenatide on energy intake in healthy subjects and patients with type 2 diabetes – relationship to gastric emptying and intragastric distribution. Nutrients.2020 Jul 1;12(7):1962
  56. Xie C, Wang X, Jones KL, Horowitz M, Sun Z, Little TJ, Rayner CK, Wu T. Comparative effects of intraduodenal glucose and fat on blood pressure and heart rate in type 2 diabetes. Front Nutr 2020 Nov 9;7:582314.
  57. Rayner CK, Wu T, Aroda VR, Whittington C, Kanters S, Guyot P, Shaunic A, Horowitz M. Gastrointestinal adverse events with insulin glargine/lixisenatide fixed-ratio combination versus GLP-1 RAs in people with type 2 diabetes mellitus: a network meta-analysis. Diabetes Obes Metab. 2021 Jan;23(1):136-146.
  58. Xie C, Huang W, Wang X, Trahair LG, Pham HT, Marathe CS, Young RL, Jones KL, Horowitz M, Rayner CK, Wu T. Gastric emptying in health and type 2 diabetes: an evaluation using a 75g oral glucose drink. Diabetes Res Clin Pract. 2021 Jan;171:108610.
  59. Qiu S, Cai X, Sun Z, Wu T, Schumann U. Is estimated cardiorespiratory fitness an effective predictor for cardiovascular and all-cause mortality? A meta-analysis. Atherosclerosis. 2021;330:22-28.
  60. Qiu S, Cai X, Xie B, Yuan Y, Sun Z, Wu T. Normalized creatinine-to-cystatin C ratio and risk of diabetes in middle-aged and older adults: the China Health and Retirement Longitudinal Study. Diabetes Metab J. 2022 Mar 7. doi: 10.4093/dmj.2021.0074.
  61. Qiu S, Cai X, Yuan Y, Xie B, Sun Z, Wu T. Changes in creatine-to-cystatin C ratio over 4-year, risk of diabetes, and cardiometabolic control: the China Health and Retirement Longitudinal Study. J Diabetes. 2021 Dec;13(12):1025-1033
  62. Xie C, Huang W, Watson LE, Soenen S, Young RL, Jones KL, Horowitz M, Rayner CK, Wu T. Plasma GLP-1 response to oral and intraduodenal nutrients in health and type 2 diabetes – impact on gastric emptying. J Clin Endo Metab. 2022 Mar 24;107(4):e1643-e1652.
  63. Qiu S, Cai X, Yuan Y, Xie B, Sun Z, Wang D, Wu T. Muscle strength and prediabetes progression and regression in middle-aged and older adults: a prospective cohort study. J Cachexia Scarcopenia Muscle. 2022 Apr;13(2):909-918. 
  64. Qiu S, Cai X, Zheng P, Yuan Y, Xu Y, Jia L, Sun Z, Wu T. Changes in objectively-measured physical capability over 4-year, risk of diabetes, and glycaemic control in older adults: the China Health and Retirement Longitudinal Study. Diabetes Res Clin Pract. 2021 Dec 28;184:109186.
  65. Wang X, Chen C, Xie C, Huang W, Young RL, Jones KL, Horowitz M, Rayner CK, Sun Z, Wu T. Serum bile acid response to oral glucose is attenuated in patients with early type 2 diabetes and correlates with 2h plasma glucose in individuals without diabetes. Diabetes Obes Metab. 2022 Jun;24(6):1132-1142.
  66. Jones KL, Trahair LG, Nauck MA, Wu T, Stevens JE, Buttfield MD, Hatzinikolas S, Pham H, Meier JJ, Rayner CK, Horowitz M. Measurement of gastric emptying using a 13C-octanoic acid breath test with Wagner-Nelson analysis and scintigraphy in type 2 diabetes. Exp Clin Endocrinol Diabetes. 2022;130(11):1132-1142. 
  67. Marathe CS, Pham H, Wu T, Trahair LG, Rigda RS, Buttfield MDM, Hatzinikolas S, Lange K, Rayner CK, Mari A, Horowitz M, Jones KL. Acute administration of the GLP-1 agonist, lixisenatide, diminishes postprandial insulin secretion in healthy subjects but not in type 2 diabetes, associated with slowing of gastric emptying. Diabetes Ther. 2022;13(6):1245-1249.
  68. Zhang X, Cheng Z, Dong s, Rayner CK, Wu T, Zhong M,  Zhang G, Wang K, Hu S. Effects of ileal glucose infusion on enteropancreatic hormone secretion in humans: relationship to glucose absorption. Metabolism. 2022 Jun;131:155198. 
  69. Sang M, Liu Y, Wu T, Zhou X, Wang D, Sun Z, Qiu S. Association of a novel electrolyte index, SUSPPUP, base on the measurement of fasting serum and spot urinary sodium and potassium, with prediabetes and diabetes in Chinese population. Clin Chim Acta. 2022 May 4:S0009-8981(22)01134-2. 
  70. Yao J, Li W, Liu Y, Wu T, Wang D, Arezina R, Sun Z, Qiu S. Investigation of the association between lens autofluorescence ratio and diabetes: a cross-sectional study. Photodiagnosis Photodyn Ther. 2022 Apr 28:102888. 
  71. Xie B, Cai X, Zhu Y, Sun Z, Qiu S, Wu T. Accelerometer-measured light-intensity physical activity and risk of cardiovascular disease or death in older adults: A meta-analysis. Kardiol Pol. 2022;80(7-8):774-781.
  72. Sang M, Xie C, Qiu S, Wang X, Horowitz M, Jones KL, Rayner CK, Wu T. Cholecystectomy is associated with dysglycaemia: cross-sectional and prospective analyses. Diabetes Obes Metab. 2022 Aug;24(8):1656-1660.
  73. Qiu S, Cai X, Yuan Y, Xie B, Sun Z, Wu T. Is imaging -based muscle quantity associated with risk of diabetes? A meta-analysis of cohort studies. Diabetes Res Clin Pract. 2022 [in press]
  74. Jalleh RJ, Wu T, Jones KL, Rayner CK, Horowitz M, Marathe CS. Relationships of glucose, GLP-1 and insulin secretion with gastric emptying after a 75g glucose load in type 2 diabetes. J Clin Endocrinol Metab. 2022 Aug 18;107(9):e3850-e3856.
  75. Sang M*, Wu T* (co-first author), Zhou X, Horowitz M, Jones KL, Qiu S, Guo H, Wang B, Rayner CK#, Sun Z#.  Prevalence of gastrointestinal symptoms in Chinese community-dwelling adults with and without diabetes. Nutrients. 2022 Aug 26;14(17):3506.
  76. Qiu S, Wang Q, Cai X, Sun Z, Wu T. Circulating irisin in nonalcoholic fatty liver disease: an updated meta-analysis. Endokrynologia Polska. 2023;74(1):47-54.
  77. Huang W, Xie C, Albrechtsen NJW, Jones KL, Horowitz M, Rayner CK, Wu T. The ‘early’ postprandial glucagon response is related to the rate of gastric emptying in type 2 diabetes. Peptides. 2023 Mar;161:170941.
  78. Qiu S, Wang Q, Chen W, Xie B, Wang D, Cai X, Sun Z, Wu T. Cumulative muscle strength and risk of cardiovascular disease and all-cause mortality: a prospective cohort study. Arch Med Res. 2023 Apr;54(3):261-269.
  79. Li Y, Zhang D, Mo Y, Zeng T, Wu T, Liu L, Zhang H, Chen C. Simultaneous determination of sex hormones and bile acids in rate plasma using a liquid chromatography-tandem mass spectrometry method. J Pharm Biomed Anal. 2023;223:115139.
  80. Qiu S, Zhu Y, Xie B, Chen W, Wang D, Cai X, Sun Z, Wu T. Prediabetes progression and regression on objectively measured physical function: a prospective cohort study. Diabetes Metab J. 2023 [in press]
  81. Jalleh RJ, Trahair LG, Wu T, Standfield S, Feinle-Bisset C, Rayner CK, Horowitz M, Jones KL. Effect of gastric distension with concurrent small intestinal saline or glucose infusion on incretin hormone secretion in healthy subjects. Diabetes Obes Metab. 2023 Jul:25(7):1849-1854.
  82. Xie C, Jalleh RJ, Watson LE, Huang W, Sun Y, Jones KL, Horowitz M, Rayner CK, Wu T. Determinants of blood glucose concentrations following a high carbohydrate meal in type 2 diabetes: A multiple linear regression analysis. Diabetes Res Clin Pract. 2023 Apr;198:110606.
  83. Xie C, Huang W, Sun Y, Xiang C, Trahair L, Jones KL, Horowitz M, Rayner CK, Wu T. Disparities in the glycaemic and incretin responses to intraduodenal glucose infusion between healthy young men and women. J Clin Endocrinol Metab. 2023 Aug 18;108(9):e712-e719.
  84. Zhou X, Lu H, Sang M, Qiu S, Yuan Y, Wu T, Chen J, Sun Z. Impaired antibody response to inactivated COVID-19 vaccines in hospitalized patients with type 2 diabetes. Hum Vaccin Immunother. 2023;19(1):2184754.
  85. Qiu S, Cai X, Liang Y, Chen W, Wang D, Sun Z, Xie B, Wu T. Cumulative muscle strength and risk of diabetes: A prospective cohort study with mediation analysis. Diabetes Res Clin Pract. 2023 Mar;197:110526.
  86. Huang W, Xie C, Wewer Albrechtesen JJ, Sang M, Sun Z, Jones KL, Horowitz M, Rayner CK, Wu T. Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes. Peptides. 2023 Nov;169:171092.
  87. Qiu S, Cai X, Zhou X, Xu J, Sun Z, Guo H, Wu T. Muscle quality in relation to prediabetes phenotypes: a population-based study with mediation analysis. J Clin Endocrinol Metab. [in press]

 

Reviews

  1. Wu T, Rayner CK, Jones K, Horowitz M. Dietary effects on incretin hormone secretion. Vitam Horm 2010;84:81-110.
  2. Wu T, Rayner CK, Young RL, Horowitz M. Gut motility and enteroendocrine secretion. Curr Opin Pharmacol. 2013;13:928-34. 
  3. Thazhath SS, Wu T, Young RL, Horowitz M, Rayner CK. Glucose absorption in small intestinal diseases. Expert Rev Gastroenterol Hepatol. 2014;8:301-12.
  4. Mignone LE, Wu T, Horowitz M, Rayner CK. Whey protein: The "whey" forward for treatment of type 2 diabetes? World J Diabetes. 2015;6:1274-84.
  5. Wu T, Rayner CK, Horowitz M. Inter-regulation of gastric emptying and incretin hormone secretion – implications for postprandial glycaemic control. Biomark Med. 2016;10(11):1167-79.
  6. Wu T, Horowitz M, Rayner CK. New insights into the anti-diabetic actions of metformin: from the liver to the gut. Expert Rev Gastroenterol Hepatol. 2017;11:157-66.
  7. Xie C, Wang X, Young RL, Horowitz M, Rayner CK, Wu T. Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control. Front Endocrinol. 2018 Sep 27;9:576. 
  8. Kreuch D, Keating DJ, Wu T, Horowitz M, Rayner CK, Young RL. Gut mechanisms linking intestinal sweet sensing to glycemic control. Front Endocrinol. 2018 Dec 4;9:741.
  9. Sansome DJ, Xie C, Veedfald S, Horowitz M, Rayer CK, Wu T. Role of bile acids in glucose lowering by metformin in type 2 diabetes. Diabetes Obes Metab. 2020 Feb;22(2):141-148.
  10. Huang W, Xie C, Young RL, Zhao J, Ebendorff-Heidepriem H, Jones KL, Rayner CK, Wu T. Development of innovative tools for investigation of nutrient-gut interaction. World J Gastroenterol. 2020 Jul 7;26(5):3562-3576
  11. Xie C, Jones KL, Rayner CK, Wu T. Enteroendocrine Hormone Secretion and Metabolic Control: Importance of the Region of the Gut Stimulation. Pharmaceutics. 2020 Aug 21;12(9):E790
  12. Marathe CS, Jones KL, Wu T, Rayner CK, Horowitz M. Gastrointestinal autonomic neuropathy in diabetes. Auton Neurosci. 2020 Aug 15;229:102718
  13. Wu T, Rayner CK, Jones KL, Xie C, Marathe CS, Horowitz M. Role of intestinal glucose absorption in glucose tolerance. Curr Opin Pharmacol. 2020;55:116-124.
  14. Borg MJ, Rayner CK, Jones KL, Horowitz M, Xie C, Wu T. Gastrointestinal mechanisms underlying the cardiovascular effect of metformin. Pharmaceuticals. 2020;13(11):410.
  15. Borg MJ, Xie C, Rayner CK, Horowitz M, Jones KL, Wu T. Potential for gut peptide-based therapy in postprandial hypotension. Nutrients. 2021;13(8):2826.
  16. Xie C, Huang W, Young RL, Jones KL, Horowitz M, Rayner CK, Wu T. Role of bile acids in the regulation of food intake, and their dysregulation in metabolic disease. Nutrients. 2021;13(4):1104.
  17. Dong S, Qian L, Cheng Z, Chen C, Wang K, Hu S, Zhang X, Wu T. Lactate and myocardiac energy metabolism. Front Physiol. 2021 [In press]
  18. Huang W, Wu T*, Xie C, Rayner CK, Priest C, Ebendorff-Heidepriem, Zhao J* (*joint sensor author). Sensing intra- and extracellular Ca2+ in the islet of Langerhans. Advanced Functional Materials. 2021 [In press]
  19. Normal and disordered gastric emptying in diabetes: recent insights into (patho)physiology, management and impact on glycaemic control. Jalleh RJ, Jones KL, Rayner CK, Marathe CS, Wu T, Horowitz M. Diabetologia.2022 Dec;65:1981-1993.

Editorials

  1. Horowitz M, Wu T, Deane AM, Jones KL, Rayner CK. Dipeptidyl Peptidase 4 and the known unknown. Diabetes 2016;65:2124-26.
  2. Rayner CK, Jones KL, Wu T, Horowitz M. Gut feelings about diabetes and GLP-1 receptor agonists – lessons to be learnt from studies in functional gastrointestinal disorders. Diabetes Obes Metab. 2017;19:309-12.
  3. Wu T, Rayner CK, Marathe CS, Jones KL, Horowitz M. Glucagon receptor signalling – backwards and forwards. Expert Opin Investig Drugs. 2018  Feb;27(2):135-138.
  4. Marathe CS, Rayner CK, Wu T, Jones KL, Horowitz M. Gastric emptying and the personalized management of type 1 diabetes. J Clin Endocriol Metab. 2018 Sep 1;103(9):3503-3506.
  5. Horowitz M, Wu T, Rayner CK, Marathe CS, Jones KL. Spontaneous or deliberate: effects of acute variations in glycemia on gastric emptying in type 1 diabetes. Diabetes Care 2021 Feb;44(2):316-318.
  6. Qiu S, Ma J, Wu T. Editorial: Management of diabetes and its complications: a focus on endothelial dysfunction. Front Endocrinol. 2022 Mar 18;13:857983.
  7. Wu T, Rayner CK, Jones KL, Horowitz M. Seize the whey! Whey preloads for control of postprandial glycemia in metabolic disease. Am J Clin Nutr. 2023;118(2):345-346.

Letters

  1. Wu T, Marathe CS, Horowitz M, Jones KL, Rayner CK. Comment on Russell-Jones et al. Diabetes Care 2017;40:943–950. Comment on Bowering et al. Diabetes Care 2017;40:951–957. Diabetes Care. 2018;41:e27-28.
  2. Sansome DJ, Xie C, Veedfald S, Horowitz M, Rayer CK, Wu T. Statins and glycaemic control in type 2 diabetes: are bile acids relevant? Br J Clin Pharmacol. 2020 Dec;86(12):2538-2539.
  3. Horowitz M, Rayner CK, Marathe CS, Wu T, Jones KL. Glucagon-like peptide-1 receptor agonists and the appropriate measurement of gastric emptying. Diabetes Obes Metab. 2020 Dec;22(12):2504-2506.
  4. Marathe CS, Jones KL, Rayner CK, Wu T, Horowitz M. Comment on Rosenstock et al.  Impact of a Weekly Glucagon-Like Peptide-1 Receptor Agonist, Albiglutide, on Glycemic Control and on Reducing Prandial Insulin Use in Type 2 Diabetes Inadequately Controlled on Multiple Insulin Therapy: A Randomized Trial. Diabetes Care. 2021 [in press]
  5. Horowitz M, Rayner CK, Marathe CS, Wu T, Umapathysivam M, Jones KL. Response to Dahl et al: Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes. Diabetes Obes Metab. 2021 Oct;23(10):2411-2413. 
  6. Sang M, Sun Z, Wu T. Inflammatory bowel disease and diabetes: is there a link? World J Diabetes. 2022 Feb 15;13(2):126-128. 
  7. Wu T, Rayner CK, Jones KL, Horowitz M, Feinle-Bisset C, Standfield SD, Xie C, Deacon CF, Holst JJ, Wewer Albrechtsen NJ. Measurement of plasma glucagon in humans – a shift in the performance of a current commercially available radioimmunoassy kit. Diabetes Obes Metab. 2022  Jun;24(6):1182-1184.
  8. Qiu S, Cai X, Sun Z, Wu T. Comment on ‘Prediabetes is an independent risk factor for sarcopenia in older men, but not in older women: the Bunkyo Health Study’ by Kaga et al. J Cachexia Sarcopenia Muscle. 2023;14(5):2452-2453.

Book chapters

  1. Wu T, Rayner CK, Horowitz M. Incretins. Handb Exp Pharmacol. 2016;233:137-71.
  2. Watson LE, Wu T, Horowitz M, Rayner CK. Whey protein and diabetes. Milk in Human Health and Disease Across Lifespan. 2017 [edited by Watson RR et al.]
  3. Marathe CS, Rayner CK, Wu T, Jones KL, Horowitz M. Diabetes and the gastrointestinal tract. In book: 2020. In: Kuipers, EJ (ed.) Encyclopedia of Gastroenterology, 2nd edition, pp. 9-12. Oxford: Academic Press.
  4. Marathe CS, Rayner CK, Wu T, Jones KL, Horowitz M. Gastrointestinal disorders in diabetes. In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. 2020 Jan 11.
  5. Jones KL, Marathe CS, Wu T, Rayner CK, Horowitz M. Gastrointestinal neurophathy. Diabetic Neuropathy: Clinical Management (3rd ed). 2021 [in press]

 

Date Position Institution name
2021 - ongoing Associate Professor (Level D) The University of Adelaide
2020 - ongoing THRF Mid-Career Fellow (Level C) The University of Adelaide
2018 - 2020 RAH Florey Fellow (GFS-5) Royal Adelaide Hospital
2015 - 2017 RAH Mary Overton Early Career Fellow (Level A) The University of Adelaide
2014 - 2014 Clinical Research Fellow (Level A) The University of Adelaide
2007 - 2009 Physician Trainee Zhongda Hospital Southeast University
2006 - 2007 Intern (First Class) Zhongda Hospital Southeast University

Date Type Title Institution Name Country Amount
2021 Research Award Emerging Leader Award Faculty of Health and Medical Sciences, The University of Adelaide Australia -
2020 Fellowship THRF Mid-Career Fellowship The Hospital Research Foundation Australia -
2019 Award Clinical Science Poster Award Australian Diabetes Society Australia -
2019 Award Travel Award European Association for the Study of Diabetes Germany -
2018 Award Northern Communities Health Foundation Derek Frewin Early Career Research Award Northern Communities Health Foundation Australia -
2018 Fellowship Royal Adelaide Hospital Florey Fellowship Royal Adelaide Hospital Research Committee Australia -
2016 Award Executive Dean's Award for Research Excellence (Early Career Researcher) The University of Adelaide - -
2016 Award Travel Award European Association for the Study of Diabetes - €1500
2016 Award Travel Award University of Adelaide, School of Medicine Australia 2835
2015 Fellowship Early Career Fellowship Royal Adelaide Hospital Australia -
2015 Recognition Best Poster Australian Diabetes Society Australia -
2015 Award Travel Grant University of Adelaide, Discipline of Medicine Australia -
2014 Research Award University Doctoral Research Medal University of Adelaide Australia -
2013 Recognition Dean's commendation for thesis excellence University of Adelaide Australia -
2013 Award Travel Award, Diabetes Congress International Diabetes Federation (IDF) Australia -
2013 Fellowship Travelling Fellowship University of Adelaide, Discipline of Medicine Australia 2600
2012 Award Travel Award European Association for the Study of Diabetes - €2000
2011 Award Travel Award European Association for the Study of Diabetes - €2000
2011 Fellowship Postgraduate Travelling Fellowship University of Adelaide Australia 1700
2010 Recognition Best Poster Presentation University of Adelaide, Research Expo Australia -
2009 Recognition Outstanding Postgraduate in Clinical Medicine Southeast University Australia -
2009 Scholarship Postgraduate Scholarship China Scholarship Council China -
2009 Scholarship Postgraduate Supplementary Scholarship Centre of Research Excellence in Translating Nutritional Science to Good Health Australia -
2007 Scholarship First-class postgraduate scholarship Southeast University China -
2007 Recognition Outstanding Graduate in Clinical Medicine Southeast University China -
2006 Recognition 'Excellent Student Researcher' in the Student Research Training Program (SRTP) Southeast University China -
2004 Scholarship 'Zi-guang' Scholarship Southeast University Australia -

Date Institution name Country Title
2009 - 2013 University of Adelaide Australia Doctor of Philosophy
2007 - 2009 Southeast University China Master of Clinical Medicine
2002 - 2007 Southeast University China Bachelor of Clinical Medicine

Year Citation
2026 Xie, C., White, J. B., Huang, W., Horowitz, M., Rayner, C. K., Verjans, J. W., . . . Wu, T. (2026). Endogenous Glucagon-Like Peptide 1 Enhanced by Vildagliptin Reduces Triglyceride Appearance During Intraduodenal Fat Infusion in Type 2 Diabetes.. Diabetes, db250980.
DOI
2025 Xie, C., Iroga, P., Bound, M. J., Grivell, J., Huang, W., Jones, K. L., . . . Wu, T. (2025). Impact of the timing of metformin administration on the plasma lactate response to intraduodenal glucose infusion in type 2 diabetes. Diabetes Obesity and Metabolism, 27(3), 1614-1617.
DOI Scopus2 WoS2
2025 Jalleh, R. J., Marathe, C. S., Rayner, C. K., Jones, K. L., Umapathysivam, M. M., Wu, T., . . . Horowitz, M. (2025). Physiology and pharmacology of effects of GLP-1 based therapies on gastric, biliary and intestinal motility. Endocrinology, 166(1), bqae155-1-bqae155-14.
DOI Scopus18 WoS15 Europe PMC10
2025 Quast, D. R., Xie, C., Bound, M. J., Grivell, J., Hatzinikolas, S., Jones, K. L., . . . Wu, T. (2025). Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes - a double-blind, placebo-controlled crossover study.. Diabetes, 74(4), 611-618.
DOI Scopus7 WoS6 Europe PMC5
2025 Zhou, X., Wu, T., Sang, M., Qiu, S., Wang, B., Guo, H., . . . Sun, Z. (2025). Variations in blood pressure after a 75g oral glucose load and their implications for detecting hypertension and postprandial hypotension in Chinese adults: a cross-sectional study.. European journal of preventive cardiology, 32(14), zwaf217.
DOI Scopus2 WoS1
2025 Kabthymer, R. H., Wu, T., Beigrezaei, S., Franco, P. O. H., Hodge, A. M., & de Courten, P. B. (2025). The association of sweetened beverage intake with risk of type 2 diabetes in an Australian population: A longitudinal study.. Diabetes Metab, 51(6), 101665.
DOI Scopus2 Europe PMC1
2025 Borg, M. J., Xie, C., Chen, C., Bound, M. J., Grivell, J., Huang, W., . . . Wu, T. (2025). Metformin slows intestinal glucose absorption in type 2 diabetes, irrespective of the timing of its administration. Diabetes Obesity and Metabolism, 27(9), 5370-5372.
DOI Scopus1 WoS1 Europe PMC2
2025 Li, T., Rayner, C. K., Horowitz, M., Jones, K., Xie, C., Huang, W., . . . Wu, T. (2025). The Impact of Tea Consumption on Prediabetes Regression and Progression: A Prospective Cohort Study. Nutrients, 17(14), 2366.
DOI
2025 Bannon, C. A., Walters, J. R. F., Wu, T., Kay, R. G., Punnoose, A., Spiller, R. C., . . . Gribble, F. M. (2025). Insulin-like peptide 5 is released in response to bile acid in the rectum and is associated with diarrhoea severity in patients with bile acid diarrhoea.. Gut, 75(2), gutjnl-2025-335393.
DOI Scopus3 WoS3 Europe PMC1
2025 Anjom-Shoae, J., Wu, T., & Horowitz, M. (2025). Proteins and the crossroads of diet and type 2 diabetes. American Journal of Clinical Nutrition, 122(5), 1143-1144.
DOI
2025 Cai, X., Xu, C., Gu, Z., Wu, T., & Qiu, S. (2025). Development of a scoring system for vitality capacity assessment in older adults: a population-based study. European Geriatric Medicine.
DOI
2025 Wu, T., Rayner, C. K., Jones, K. L., & Horowitz, M. (2025). Dual incretin therapy for type 2 diabetes inadequately controlled on basal insulin in Chinese adults: clinical and research implications.. The lancet. Diabetes & endocrinology, 13(12), S2213-8587(25)00282-7.
DOI
2025 Wu, T., Horowitz, M., Jones, K. L., & Rayner, C. K. (2025). Reframing metformin as a gut-targeted glucose-lowering therapy: mechanistic insights and translational relevance. Molecular Metabolism, 102, 102276.
DOI
2024 Huang, W., O'Hara, S. E., Xie, C., Liu, N., Rayner, C. K., Nicholas, L. M., & Wu, T. (2024). Effects of a bitter substance, denatonium benzoate, on pancreatic hormone secretion. American Journal of Physiology: Endocrinology and Metabolism, 326(4), E537-E544.
DOI Scopus4 WoS4 Europe PMC3
2024 Xie, C., Iroga, P., Bound, M. J., Grivell, J., Huang, W., Jones, K. L., . . . Wu, T. (2024). Impact of the timing of metformin administration on glycaemic and glucagon-like peptide-1 responses to intraduodenal glucose infusion in type 2 diabetes: a double-blind, randomised, placebo-controlled, crossover study. Diabetologia, 67(7), 1260-1270.
DOI Scopus18 WoS16 Europe PMC16
2024 Xiang, C., Sun, Y., Luo, Y., Xie, C., Huang, W., Sun, Z., . . . Wu, T. (2024). Gastric emptying of a glucose drink is predictive of the glycaemic response to oral glucose and mixed meals, but unrelated to antecedent glycaemic control, in type 2 diabetes. Nutrition and Diabetes, 14(1, article no. 13), 13-1-13-7.
DOI Scopus5 WoS4 Europe PMC3
2024 Xiang, C., Sun, Y., Luo, Y., Xie, C., Huang, W., Jones, K. L., . . . Wu, T. (2024). Gastric emptying is slower in women than men with type 2 diabetes and impacts on postprandial glycaemia. Diabetes, Obesity and Metabolism, 26(8), 3119-3127.
DOI Scopus5 WoS5 Europe PMC3
2024 Sun, Y., Luo, Y., Xiang, C., Xie, C., Huang, W., Sun, Z., . . . Wu, T. (2024). Gastric emptying in newly diagnosed, treatment-naïve Han Chinese with type 2 diabetes and the impact of 4-week insulin pump therapy. Diabetes, Obesity and Metabolism, 26(8), 3078-3087.
DOI Scopus3 WoS3 Europe PMC2
2024 Jones, K. L., Marathe, C. S., Wu, T., Rayner, C. K., Nauck, M., & Horowitz, M. (2024). Getting the measure of the pressure: Optimal assessment of the effects of glucagon-like peptide-1 receptor agonists on blood pressure. Diabetes, Obesity and Metabolism, 26(8), 3003-3005.
DOI Scopus5 WoS5 Europe PMC5
2024 Xie, C., Huang, W., Rayner, C. K., Horowitz, M., & Wu, T. (2024). Letter to the Editor From Xie et al: "The 13C Glucose Breath Test Accurately Identifies Insulin Resistance in People With Type 1 Diabetes".. The Journal of clinical endocrinology and metabolism, 109(10), dgae366.
DOI Scopus1 WoS1
2024 Kovoor, J. G., Rayner, C. K., Wu, T., Jalleh, R. J., Maddern, G. J., Horowitz, M., & Jones, K. L. (2024). Effect of lixisenatide on liquid gastric emptying in type 2 diabetes - Implications for the use of GLP-1 receptor agonists before procedures. Journal of Diabetes and Its Complications, 38(8), 108793-1-108793-3.
DOI Scopus8 WoS8 Europe PMC7
2024 Zhang, D., Zhu, J., Wewer Albrechtsen, N. J., Rayner, C. K., Saffery, R., Zhang, H., . . . Wu, T. (2024). Impairments of insulin and glucagon sensitivity in Chinese women with gestational diabetes mellitus.. Diabetes, Obesity and Metabolism, 26(9), 3926-3934.
DOI Scopus2 WoS2 Europe PMC1
2024 Huang, W., Xie, C., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2024). Sex differences in the plasma glucagon responses to a high carbohydrate meal and a glucose drink in type 2 diabetes. Diabetes Research and Clinical Practice, 214, 111769-1-111769-3.
DOI Scopus4 WoS5 Europe PMC4
2024 Quast, D. R., Lancaster, D., Xie, C., Bound, M. J., Grivell, J., Jones, K. L., . . . Nauck, M. A. (2024). Randomised comparison of intravenous and subcutaneous routes of glucagon-like peptide-1 administration for lowering plasma glucose in hyperglycaemic subjects with type 2 diabetes. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics, 26(9), 3897-3905.
DOI Scopus1 WoS1 Europe PMC1
2024 Jones, K. L., Wu, T., & Horowitz, M. (2024). Risk Assessment and Prevention of Falls. JAMA: Journal of the American Medical Association, 332(7), 11824-1.
DOI
2024 Wang, Z., Cao, Q. -Y., Xiang, C., Yu, C., Xie, C., Luo, B., . . . Teng, G. -J. (2024). Bariatric arterial embolization slows gastric emptying and improves postprandial glycaemia in obese dogs with impaired glucose tolerance.. Diabetes Obes Metab, 26(10), 4490-4500.
DOI Europe PMC1
2024 Li, T., Sang, M., Wang, J., Sun, Z., Wang, D., Xie, C., . . . Wu, T. (2024). Dark tea consumption is associated with a reduced risk of dysglycaemia and increased urinary glucose and sodium excretion in Chinese adults.. Diabetes, obesity & metabolism, 26(10), 4705-4712.
DOI Scopus3 WoS3 Europe PMC2
2024 Sun, Y., Luo, Y., Xie, C., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2024). Relevance of gastric emptying to the timing of prandial insulin administration in hospitalised patients with diabetes.. Diabetes research and clinical practice, 217, 111877.
DOI
2024 Huang, W., Xie, C., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2024). Reply to 'Letter to the Editor: Sex differences in the plasma glucagon responses to a high carbohydrate meal and a glucose drink in type 2 diabetes'.. Diabetes Res Clin Pract, 217, 111880.
DOI
2024 Jalleh, R. J., Plummer, M. P., Marathe, C. S., Umapathysivam, M. M., Quast, D. R., Rayner, C. K., . . . Nauck, M. A. (2024). Clinical consequences of delayed gastric emptying with GLP-1 receptor agonists and tirzepatide. The Journal of Clinical Endocrinology & Metabolism, 110(1), 1-15.
DOI Scopus51 WoS41 Europe PMC31
2024 Rose, B. D., Pezos, N., Choo, J. M., Wu, T., Rogers, G. B., Ivey, K. L., . . . Young, R. L. (2024). Host or the Hosted? Effects of Non-Nutritive Sweeteners on Intestinal and Microbial Mechanisms of Glycemic Control. Nutrients, 16(21), 3628-1-3628-15.
DOI
2023 Qiu, S., Cai, X., Zhou, X., Xu, J., Sun, Z., Guo, H., & Wu, T. (2023). Muscle quality in relation to prediabetes phenotypes: a population-based study with mediation analysis.. J Clin Endocrinol Metab, 109(3), e1151-e1158.
DOI Scopus5 Europe PMC4
2023 Qiu, S., Zhu, Y., Xie, B., Chen, W., Wang, D., Cai, X., . . . Wu, T. (2023). Prediabetes Progression and Regression on Objectively- Measured Physical Function: A Prospective Cohort Study.. Diabetes & metabolism journal, 47(6), 859-868.
DOI Scopus3 WoS2 Europe PMC1
2023 Huang, W., Xie, C., Wewer Albrechtsen, N. J., Sang, M., Sun, Z., Jones, K. L., . . . Wu, T. (2023). Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes. Peptides, 169(171092), 171092-1-171092-10.
DOI Scopus4 WoS4 Europe PMC2
2023 Wu, T., Rayner, C. K., Jones, K. L., & Horowitz, M. (2023). Seize the whey! Whey preloads for control of postprandial glycemia in metabolic disease. The American Journal of Clinical Nutrition, 118(2), 345-346.
DOI Scopus2 WoS2 Europe PMC1
2023 Li, T., Xie, C., Sun, Z., & Wu, T. (2023). Research updates on the expression and function, as well as the influencing factors, of renal tubular glucose transporters in diabetes. Chinese Journal of Diabetes Mellitus, 15(12), 1302-1306.
DOI
2023 Huang, W., Xie, C., Wewer Albrechtsen, N. J., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2023). The 'early' postprandial glucagon response is related to the rate of gastric emptying in patients with type 2 diabetes. Peptides, 161(170941), 170941-1-170941-7.
DOI Scopus5 WoS5 Europe PMC2
2023 Qiu, S., Wang, Q., Chen, W., Xie, B., Wang, D., Cai, X., . . . Wu, T. (2023). Cumulative Muscle Strength and Risk of Cardiovascular Disease and All-cause mortality: A Prospective Cohort Study.. Arch Med Res, 54(3), 261-269.
DOI Scopus8 WoS6 Europe PMC6
2023 Qiu, S., Cai, X., Liang, Y., Chen, W., Wang, D., Sun, Z., . . . Wu, T. (2023). muscle strength and risk of diabetes: A prospective cohort study with mediation analysis.. Diabetes research and clinical practice, 197, 110562.
DOI Scopus8 WoS8 Europe PMC6
2023 Zhou, X., Lu, H., Sang, M., Qiu, S., Yuan, Y., Wu, T., . . . Sun, Z. (2023). Impaired antibody response to inactivated COVID-19 vaccines in hospitalized patients with type 2 diabetes.. Hum Vaccin Immunother, 19(1), 2184754.
DOI Scopus15 WoS14 Europe PMC13
2023 Xie, C., Jalleh, R. J., Watson, L. E., Huang, W., Sun, Y., Jones, K. L., . . . Wu, T. (2023). Determinants of blood glucose concentrations following a high carbohydrate meal in type 2 diabetes: A multiple linear regression analysis. Diabetes Research and Clinical Practice, 198(110606), 110606.
DOI Scopus6 WoS7 Europe PMC6
2023 Jalleh, R. J., Trahair, L. G., Wu, T., Standfield, S., Feinle-Bisset, C., Rayner, C. K., . . . Jones, K. L. (2023). Effect of gastric distension with concurrent small intestinal saline or glucose infusion on incretin hormone secretion in healthy individuals - a randomised, controlled, cross-over study.. Diabetes, obesity & metabolism, 25(7), 1849-1854.
DOI Scopus2 WoS2 Europe PMC3
2023 Xie, C., Huang, W., Sun, Y., Xiang, C., Trahair, L., Jones, K. L., . . . Wu, T. (2023). Disparities in the glycaemic and incretin responses to intraduodenal glucose infusion between healthy young men and women. Journal of Clinical Endocrinology and Metabolism, 108(9), e712-e719.
DOI Scopus20 WoS20 Europe PMC19
2023 Qiu, S., Cai, X., Sun, Z., & Wu, T. (2023). Comment on 'Prediabetes is an independent risk factor for sarcopenia in older men, but not in older women: the Bunkyo Health Study' by Kaga et al.. J Cachexia Sarcopenia Muscle, 14(5), 2452-2453.
DOI Scopus1 Europe PMC1
2022 Trahair, L. G., Nauck, M. A., Wu, T., Stevens, J. E., Buttfield, M. D., Hatzinikolas, S., . . . Jones, K. (2022). Measurement of gastric emptying using a C-13-octanoic acid breath test with Wagner-Nelson analysis and scintigraphy in type 2 diabetes.. Internal Medicine Journal, 52(S2), 54-55.
DOI
2022 Qiu, S., Wang, Q., Cai, X., Sun, Z., & Wu, T. (2022). Circulating irisin in nonalcoholic fatty liver disease: an updated meta-analysis.. Endokrynologia Polska, 74(1), 47-54.
DOI Scopus5 Europe PMC4
2022 Jalleh, R. J., Jones, K. L., Rayner, C. K., Marathe, C. S., Wu, T., & Horowitz, M. (2022). Normal and disordered gastric emptying in diabetes: recent insights into (patho)physiology, management and impact on glycaemic control.. Diabetologia, 65(12), 1981-1993.
DOI Scopus70 WoS68 Europe PMC55
2022 Li, Y., Zhang, D., Mo, Y., Zeng, T., Wu, T., Liu, L., . . . Chen, C. (2022). Simultaneous determination of sex hormones and bile acids in rat plasma using a liquid chromatography-tandem mass spectrometry method.. Journal of pharmaceutical and biomedical analysis, 223, 115139.
DOI Scopus2 WoS3 Europe PMC2
2022 Qiu, S., Cai, X., Yuan, Y., Xie, B., Sun, Z., & Wu, T. (2022). Is imaging-based muscle quantity associated with risk of diabetes? A meta-analysis of cohort studies.. Diabetes research and clinical practice, 189, 1-7.
DOI Scopus3 WoS3 Europe PMC2
2022 Dong, S., Qian, L., Cheng, Z., Chen, C., Wang, K., Hu, S., . . . Wu, T. (2022). Corrigendum: Lactate and Myocardiac Energy Metabolism (Front. Physiol., (2021), 12, (715081), 10.3389/fphys.2021.715081). Frontiers in Physiology, 13, 1 page.
DOI Scopus1 WoS1 Europe PMC1
2022 Sang, M., Wu, T., Zhou, X., Horowitz, M., Jones, K. L., Qiu, S., . . . Sun, Z. (2022). Prevalence of Gastrointestinal Symptoms in Chinese Community-Dwelling Adults with and without Diabetes. Nutrients, 14(17), 3560-1-3560-13.
DOI Scopus7 WoS6 Europe PMC5
2022 Huang, W., Wu, T., Xie, C., Rayner, C. K., Priest, C., Ebendorff-Heidepriem, H., & Zhao, J. (2022). Sensing Intra- and Extra-Cellular Ca2+ in the Islet of Langerhans. Advanced Functional Materials, 32(3), 1-24.
DOI Scopus4 WoS2
2022 Xie, C., Huang, W., Watson, L. E., Soenen, S., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Plasma GLP-1 response to oral and intraduodenal nutrients in health and type 2 diabetes - impact on gastric emptying. The Journal of Clinical Endocrinology & Metabolism, 107(4), e1643-e1652.
DOI Scopus24 WoS24 Europe PMC25
2022 Qiu, S., Cai, X., Zheng, P., Yuan, Y., Xu, Y., Jia, L., . . . Wu, T. (2022). Changes in objectively-measured physical capability over 4-year, risk of diabetes, and glycemic control in older adults: the China Health and Retirement Longitudinal Study.. Diabetes Res Clin Pract, 184, 1-8.
DOI Scopus3 WoS3 Europe PMC3
2022 Qiu, S., Cai, X., Yuan, Y., Xie, B., Sun, Z., Wang, D., & Wu, T. (2022). Muscle strength and prediabetes progression and regression in middle-aged and older adults: a prospective cohort study. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 13(2), 1-10.
DOI Scopus77 WoS67 Europe PMC62
2022 Wu, T., Rayner, C. K., Jones, K. L., Horowitz, M., Feinle-Bisset, C., Standfield, S. D., . . . Wewer Albrechtsen, N. J. (2022). Measurement of plasma glucagon in humans - a shift in the performance of a current commercially available RIA kit.. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics, 24(6), 1182-1184.
DOI Scopus16 WoS15 Europe PMC9
2022 Wang, X., Chen, C., Xie, C., Huang, W., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Serum bile acid response to oral glucose is attenuated in patients with early type 2 diabetes and correlates with 2h plasma glucose in individuals without diabetes.. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics, 24(6), 1134-1142.
DOI Scopus12 WoS11 Europe PMC13
2022 Jones, K. L., Trahair, L. G., Nauck, M. A., Wu, T., Stevens, J. E., Buttfield, M. D., . . . Horowitz, M. (2022). Measurement of gastric emptying using a 13C-octanoic acid breath test with Wagner-Nelson analysis and scintigraphy in type 2 diabetes.. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 130(11), 751-757.
DOI Scopus16 WoS14 Europe PMC13
2022 Sang, M. -M., Sun, Z. -L., & Wu, T. -Z. (2022). Inflammatory bowel disease and diabetes: Is there a link between them?. WORLD JOURNAL OF DIABETES, 13(2), 126-128.
DOI WoS10 Europe PMC10
2022 Qiu, S., Cai, X., Xie, B., Yuan, Y., Sun, Z., & Wu, T. (2022). Normalized Creatinine-to-Cystatin C Ratio and Risk of Diabetes in Middle-Aged and Older Adults: The China Health and Retirement Longitudinal Study.. Diabetes Metab J, 46(3), 1-10.
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2022 Zhang, X., Cheng, Z., Dong, S., Rayner, C., Wu, T., Zhong, M., . . . Hu, S. (2022). Effects of ileal glucose infusion on enteropancreatic hormone secretion in humans: relationship to glucose absorption.. Metabolism, 131, 1-7.
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2022 Qiu, S., Ma, J., & Wu, T. (2022). Editorial: Management of Diabetes and its Complications: A Focus on Endothelial Dysfunction.. Frontiers in endocrinology, 13, 857983.
DOI Scopus1 Europe PMC1
2022 Sang, M., Xie, C., Qiu, S., Wang, X., Horowitz, M., Jones, K. L., . . . Wu, T. (2022). Cholecystectomy is associated with dysglycaemia: cross-sectional and prospective analyses.. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics, 24(8), 1656-1660.
DOI Scopus12 WoS16 Europe PMC14
2022 Yao, J., Li, W., Liu, Y., Wu, T., Wang, D., Arezina, R., . . . Qiu, S. (2022). Investigation of the association between lens autofluorescence ratio and diabetes: a cross-sectional study.. Photodiagnosis and photodynamic therapy, 38, 1-7.
DOI Scopus1 WoS1 Europe PMC1
2022 Marathe, C. S., Pham, H., Wu, T., Trahair, L. G., Rigda, R. S., Buttfield, M. D. M., . . . Jones, K. L. (2022). Acute Administration of the GLP-1 Receptor Agonist Lixisenatide Diminishes Postprandial Insulin Secretion in Healthy Subjects But Not in Type 2 Diabetes, Associated with Slowing of Gastric Emptying. Diabetes Therapy, 13(6), 1245-1249.
DOI Scopus8 WoS8 Europe PMC6
2022 Xie, B., Cai, X., Zhu, Y., Sun, Z., Qiu, S., & Wu, T. (2022). Accelerometer-measured light-intensity physical activity and risk of cardiovascular disease or death in older adults: A meta-analysis.. Kardiologia polska, 80(7-8), 774-781.
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2022 Sang, M., Liu, Y., Wu, T., Zhou, X., Wang, D., Sun, Z., & Qiu, S. (2022). Association of a novel electrolyte index, SUSPPUP, based on the measurement of fasting serum and spot urinary sodium and potassium, with prediabetes and diabetes in Chinese population.. Clinica chimica acta; international journal of clinical chemistry, 531, 436-433.
DOI Scopus2 WoS2 Europe PMC1
2022 Jalleh, R. J., Wu, T., Jones, K. L., Rayner, C. K., Horowitz, M., & Marathe, C. S. (2022). Relationships of glucose, GLP-1 and insulin secretion with gastric emptying after a 75g glucose load in type 2 diabetes.. Journal of Clinical Endocrinology and Metabolism, 107(9), e3850-e3856.
DOI Scopus13 WoS14 Europe PMC12
2021 Xie, C., Huang, W., Wang, X., Trahair, L. G., Pham, H. T., Marathe, C. S., . . . Wu, T. (2021). Gastric emptying in health and type 2 diabetes: an evaluation using a 75g oral glucose drink. Diabetes Research and Clinical Practice, 171(108610), 1-8.
DOI Scopus26 WoS26 Europe PMC23
2021 Horowitz, M., Wu, T., Rayner, C. K., Marathe, C. S., & Jones, K. L. (2021). Spontaneous or deliberate: effects of acute variations in glycemia on gastric emptying in type 1 diabetes. Diabetes Care, 44(2), 316-318.
DOI Scopus6 WoS7 Europe PMC5
2021 Rayner, C. K., Watson, L. E., Phillips, L. K., Lange, K., Bound, M. J., Grivell, J., . . . Natali, A. (2021). Erratum to: Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: A randomized controlled trial (Diabetes Care 2020, 43, 1813–1821). Diabetes Care, 44(1), 297.
DOI Scopus1 WoS1
2021 Xie, C., Huang, W., Young, R. L., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2021). Role of bile acids in the regulation of food intake, and their dysregulation in metabolic disease. Nutrients, 13(4), 1-16.
DOI Scopus97 WoS95 Europe PMC68
2021 Sang, M., Wu, T., & Sun, Z. (2021). Pathogenesis and clinical management of diabetes-related gastrointestinal symptoms. Chinese Journal of Diabetes Mellitus, 13(5), 513-516.
DOI Scopus5
2021 Horowitz, M., Rayner, C. K., Marathe, C. S., Wu, T., Umapathysivam, M., & Jones, K. L. (2021). Response to Dahl et al: Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes. Diabetes, Obesity and Metabolism, 23(10), 2411-2413.
DOI Scopus6 WoS5 Europe PMC6
2021 Qiu, S., Cai, X., Sun, Z., Wu, T., & Schumann, U. (2021). Is estimated cardiorespiratory fitness an effective predictor for cardiovascular and all-cause mortality? A meta-analysis. Atherosclerosis, 330, 22-28.
DOI Scopus27 WoS27 Europe PMC22
2021 Qiu, S., Cai, X., Yuan, Y., Xie, B., Sun, Z., & Wu, T. (2021). Changes in creatinine-to-cystatin C ratio over 4 years, risk of diabetes, and cardiometabolic control: The China Health and Retirement Longitudinal Study. Journal of Diabetes, 13(12), 1025-1033.
DOI Scopus9 WoS9 Europe PMC9
2021 Borg, M. J., Xie, C., Rayner, C. K., Horowitz, M., Jones, K. L., & Wu, T. (2021). Potential for gut peptide‐based therapy in postprandial hypotension. Nutrients, 13(8), 2826-1-2826-14.
DOI Scopus14 WoS12 Europe PMC12
2021 Dong, S., Qian, L., Cheng, Z., Chen, C., Wang, K., Hu, S., . . . Wu, T. (2021). Lactate and Myocadiac Energy Metabolism.. Frontiers in physiology, 12, 1-12.
DOI Scopus52 WoS48 Europe PMC44
2021 Qiu, S., Cai, X., Jia, L., Sun, Z., Wu, T., Wendt, J., . . . Schumann, U. (2021). Does objectively-measured light-intensity physical activity reduce the risk of cardiovascular mortality? A meta-analysis.. Eur Heart J Qual Care Clin Outcomes, 7(5), 496-504.
DOI Scopus26 Europe PMC23
2021 Marathe, C. S., Jones, K. L., Rayner, C. K., Wu, T., & Horowitz, M. (2021). Comment on Rosenstock et al. Impact of a Weekly Glucagon-Like Peptide 1 Receptor Agonist, Albiglutide, on Glycemic Control and on Reducing Prandial Insulin Use in Type 2 Diabetes Inadequately Controlled on Multiple Insulin Therapy: A Randomized Trial. Diabetes Care 2020;43:2509–2518. Diabetes Care, 44(11), e194-e195.
DOI Scopus1
2021 Rayner, C. K., Wu, T., Aroda, V. R., Whittington, C., Kanters, S., Guyot, P., . . . Horowitz, M. (2021). Gastrointestinal adverse events with insulin glargine/lixisenatide fixed-ratio combination versus GLP-1 RAs in people with type 2 diabetes mellitus: a network meta-analysis.. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics, 23(1), 136-146.
DOI Scopus20 WoS17 Europe PMC18
2020 Sansome, D. J., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2020). Statins and glycaemic control in type 2 diabetes: Are bile acids relevant?. British Journal of Clinical Pharmacology, 86(12), 2538-2539.
DOI
2020 Jalleh, R., Pham, H., Marathe, C. S., Wu, T., Buttfield, M. D., Hatzinikolas, S., . . . Jones, K. L. (2020). Acute Effects of Lixisenatide on Energy Intake in Healthy Subjects and Patients with Type 2 Diabetes: Relationship to Gastric Emptying and Intragastric Distribution.. Nutrients, 12(7), 1962-1-1962-8.
DOI Scopus24 WoS22 Europe PMC24
2020 Xu, X., Wang, X., Sun, Z., & Wu, T. (2020). Relationship between gastric emptying rate and glucose regulation and related glucose lowering strategy. Chinese Journal of Diabetes Mellitus, 12(5), 336-339.
DOI
2020 Huang, W., Xie, C., Young, R. L., Zhao, J., Ebendorff-Heidepriem, H., Jones, K. L., . . . Wu, T. (2020). Development of innovative tools for investigation of nutrient-gut interaction. World Journal of Gastroenterology, 26(25), 3562-3576.
DOI Scopus10 WoS10 Europe PMC7
2020 Horowitz, M., Rayner, C. K., Marathe, C. S., Wu, T., & Jones, K. L. (2020). Glucagon‐like peptide‐1 receptor agonists and the appropriate measurement of gastric emptying. Diabetes, Obesity and Metabolism, 22(12), 2504-2506.
DOI Scopus27 WoS27 Europe PMC25
2020 Xie, C., Jones, K. L., Rayner, C. K., & Wu, T. (2020). Enteroendocrine hormone secretion and metabolic control: importance of the region of the gut stimulation. Pharmaceutics, 12(9), 1-23.
DOI Scopus43 WoS39 Europe PMC33
2020 Qiu, S., Cai, X., Wu, T., Sun, Z., Guo, H., Kirsten, J., . . . Schumann, U. (2020). Objectively-Measured Light-Intensity Physical Activity and Risk of Cancer Mortality: A Meta-analysis of Prospective Cohort Studies.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 29(5), 1067-1073.
DOI Scopus22 WoS21 Europe PMC17
2020 Rayner, C. K., Watson, L. E., Phillips, L. K., Lange, K., Bound, M. J., Grivell, J., . . . Natali, A. (2020). Effects of Sustained Treatment With Lixisenatide on Gastric Emptying and Postprandial Glucose Metabolism in Type 2 Diabetes: A Randomized Controlled Trial.. Diabetes Care, 43(8), 1813-1821.
DOI Scopus44 WoS45 Europe PMC43
2020 Zhang, X., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2020). Effects of proximal and distal enteral glucose infusion on cardiovascular response in health and type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 105(8), 2877-2884.
DOI Scopus5 WoS4 Europe PMC4
2020 Wang, X., Xie, C., Sun, Z., & Wu, T. (2020). Role of intestinal bile acids in the regulation of metabolic homeostasis in humans. Chinese Journal of Diabetes Mellitus, 12(4), 272-274.
DOI
2020 Wang, X., Xie, C., Marathe, C. S., Malbert, C. -H., Horowitz, M., Jones, K. L., . . . Wu, T. (2020). Disparities in gastric emptying and postprandial glycaemia between Han Chinese and Caucasians with type 2 diabetes.. Diabetes Research and Clinical Practice, 159(107951), 107951-1-107951-6.
DOI Scopus26 WoS27 Europe PMC24
2020 Marathe, C. S., Pham, H., Marathe, J. A., Trahair, L. G., Huynh, L., Wu, T., . . . Jones, K. L. (2020). The relationship between plasma GIP and GLP-1 levels in individuals with normal and impaired glucose tolerance.. Acta Diabetologica, 57(5), 583-587.
DOI Scopus10 WoS8 Europe PMC3
2020 Jones, K. L., Huynh, L. Q., Hatzinikolas, S., Rigda, R. S., Phillips, L. K., Pham, H. T., . . . Horowitz, M. (2020). Exenatide once weekly slows gastric emptying of solids and liquids in healthy, overweight, subjects under steady-state concentrations. Diabetes, Obesity and Metabolism, 22(5), 788-797.
DOI Scopus64 WoS61 Europe PMC54
2020 Huang, W., Wu, T., Shallan, A., Kostecki, R., Rayner, C. K., Priest, C., . . . Zhao, J. (2020). A multiplexed microfluidic platform towards interrogating endocrine function: simultaneous sensing of extracellular Ca²⁺ and hormone. ACS Sensors, 5(2), 490-499.
DOI Scopus7 WoS6 Europe PMC3
2020 Sansome, D. J., Xie, C., Veedfald, S., Horowitz, M., Rayner, C. K., & Wu, T. (2020). Mechanism of glucose-lowering by metformin in type 2 diabetes: role of bile acids. Diabetes, Obesity and Metabolism, 22(2), 141-148.
DOI Scopus77 WoS69 Europe PMC60
2020 Xie, C., Wang, X., Jones, K. L., Horowitz, M., Sun, Z., Little, T. J., . . . Wu, T. (2020). Role of endogenous glucagon-like peptide-1 enhanced by vildagliptin in the glycaemic and energy expenditure responses to intraduodenal fat infusion in type 2 diabetes. Diabetes, obesity & metabolism, 22(3), 383-392.
DOI Scopus15 WoS13 Europe PMC10
2020 Marathe, C. S., Jones, K. L., Wu, T., Rayner, C. K., & Horowitz, M. (2020). Gastrointestinal autonomic neuropathy in diabetes. Autonomic Neuroscience: Basic and Clinical, 229(102718), 1-9.
DOI Scopus31 WoS23 Europe PMC19
2020 Borg, M. J., Rayner, C. K., Jones, K. L., Horowitz, M., Xie, C., & Wu, T. (2020). Gastrointestinal mechanisms underlying the cardiovascular effect of metformin. Pharmaceuticals, 13(11), 1-14.
DOI Scopus13 WoS11 Europe PMC7
2020 Wu, T., Rayner, C. K., Jones, K. L., Xie, C., Marathe, C., & Horowitz, M. (2020). Role of intestinal glucose absorption in glucose tolerance. Current Opinion in Pharmacology, 55, 116-124.
DOI Scopus37 WoS35 Europe PMC27
2020 Xie, C., Wang, X., Jones, K. L., Horowitz, M., Sun, Z., Little, T. J., . . . Wu, T. (2020). Comparative effects of intraduodenal glucose and fat infusion on blood pressure and heart rate in type 2 diabetes. Frontiers in Nutrition, 7(582314), 1-6.
DOI Scopus5 WoS4 Europe PMC3
2020 Stevens, J., Buttfield, M., Wu, T., Hatzinikolas, S., Pham, H., Lange, K., . . . Jones, K. (2020). Effects of sitagliptin on gastric emptying of, and the glycaemic and blood pressure responses to, a carbohydrate meal in type 2 diabetes. Diabetes, Obesity and Metabolism, 22(1), 51-58.
DOI Scopus22 WoS21 Europe PMC20
2019 Borg, M. J., Bound, M., Grivell, J., Sun, Z., Jones, K. L., Horowitz, M., . . . Wu, T. (2019). Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes. Diabetes, Obesity and Metabolism, 21(3), 640-647.
DOI Scopus45 WoS42 Europe PMC39
2019 Watson, L. E., Phillips, L. K., Wu, T., Bound, M. J., Checklin, H., Grivell, J., . . . Rayner, C. K. (2019). Title: Differentiating the effects of whey protein and guar gum preloads on postprandial glycemia in type 2 diabetes. Clinical Nutrition, 38(6), 2827-2832.
DOI Scopus30 WoS28 Europe PMC25
2019 Jones, K. L., Rigda, R. S., Buttfield, M. D. M., Hatzinikolas, S., Pham, H. T., Marathe, C. S., . . . Horowitz, M. (2019). Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes. Diabetes, Obesity and Metabolism, 21(5), 1158-1167.
DOI Scopus59 WoS50 Europe PMC48
2019 Borg, M. J., Jones, K. L., Sun, Z., Horowitz, M., Rayner, C. K., & Wu, T. (2019). Metformin attenuates the postprandial fall in blood pressure in type 2 diabetes. Diabetes, Obesity and Metabolism, 21(5), 1251-1254.
DOI Scopus18 WoS16 Europe PMC13
2019 Zhang, X., Young, R. L., Bound, M., Hu, S., Jones, K. L., Horowitz, M., . . . Wu, T. (2019). Comparative effects of proximal and distal small intestinal glucose exposure on glycemia, incretin hormone secretion, and the incretin effect in health and type 2 diabetes. Diabetes Care, 42(4), 520-528.
DOI Scopus50 WoS47 Europe PMC40
2019 Pham, H., Holen, I. S., Phillips, L. K., Hatzinikolas, S., Huynh, L. Q., Wu, T., . . . Jones, K. L. (2019). The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects.. Nutrients, 11(11), 13 pages.
DOI Scopus11 WoS10 Europe PMC9
2019 Watson, L. E., Phillips, L. K., Wu, T., Bound, M. J., Jones, K. L., Horowitz, M., & Rayner, C. K. (2019). Longitudinal evaluation of gastric emptying in type 2 diabetes. Diabetes Research and Clinical Practice, 154, 27-34.
DOI Scopus12 WoS10 Europe PMC7
2019 Pham, H., Marathe, C. S., Phillips, L. K., Trahair, L. G., Hatzinikolas, S., Huynh, L., . . . Jones, K. L. (2019). Longitudinal changes in fasting and glucose-stimulated GLP-1 and GIP in healthy older subjects.. Journal of Clinical Endocrinology and Metabolism, 104(12), 6201-6206.
DOI Scopus20 WoS18 Europe PMC19
2019 Shi, R., Wang, Y., An, X., Ma, J., Wu, T., Yu, X., . . . Sun, Z. (2019). Efficacy of co-administration of Liuwei Dihuang Pills and Ginkgo biloba Tablets on albuminuria in type 2 diabetes: A 24-month, multicenter, double-blind, placebo-controlled, randomized clinical trial. Frontiers in Endocrinology, 10(FEB), 7 pages.
DOI Scopus30 WoS24 Europe PMC18
2019 Watson, L. E., Xie, C., Wang, X., Li, Z., Phillips, L. K., Sun, Z., . . . Wu, T. (2019). Gastric emptying in patients with well-controlled type 2 diabetes compared with young and older control subjects without diabetes. Journal of Clinical Endocrinology and Metabolism, 104(8), 3311-3319.
DOI Scopus82 WoS78 Europe PMC62
2019 Bitarafan, V., Fitzgerald, P. C. E., Little, T. J., Meyerhof, W., Wu, T., Horowitz, M., & Feinle-Bisset, C. (2019). Effects of intraduodenal infusion of the bitter tastant, quinine, on antropyloroduodenal motility, plasma cholecystokinin, and energy intake in healthy men. Journal of Neurogastroenterology and Motility, 25(3), 413-422.
DOI Scopus17 WoS17 Europe PMC14
2019 Watson, L. E., Phillips, L. K., Wu, T., Bound, M. J., Checklin, H. L., Grivell, J., . . . Rayner, C. K. (2019). A whey/guar “preload” improves postprandial glycaemia and glycated haemoglobin levels in type 2 diabetes: a 12-week, single-blind, randomized, placebo-controlled trial. Diabetes, Obesity and Metabolism, 21(4), 930-938.
DOI Scopus55 WoS53 Europe PMC45
2019 Bitarafan, V., Fitzgerald, P. C., Little, T. J., Meyerhof, W., Jones, K. L., Wu, T., . . . Feinle-Bisset, C. (2019). Intragastric administration of the bitter tastant, quinine, lowers the glycemic response to a nutrient drink without slowing gastric emptying, in healthy men.. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 318(2), R263-R273.
DOI Scopus29 WoS29 Europe PMC24
2019 Pham, H., Phillips, L., Marathe, C. S., Trahair, L., Hatzinikolas, S., Huynh, L. Q., . . . Jones, K. (2019). Longitudinal changes in fasting and glucose-stimulated GIP and GLP-1 in healthy older subjects. DIABETOLOGIA, 62, S128-S129.
2018 Kreuch, D., Keating, D. J., Wu, T., Horowitz, M., Rayner, C. K., & Young, R. L. (2018). Gut mechanisms linking intestinal sweet sensing to glycemic control. Frontiers in Endocrinology, 9, 741-1-741-11.
DOI Scopus35 WoS31 Europe PMC27
2018 Veedfald, S., Wu, T., Bound, M., Grivell, J., Hartmann, B., Rehfeld, J. F., . . . Rayner, C. K. (2018). Hyperosmolar duodenal saline infusion lowers circulating ghrelin and stimulates intestinal hormone release in young men. Journal of Clinical Endocrinology and Metabolism, 103(12), 4409-4418.
DOI Scopus19 WoS21 Europe PMC17
2018 Xie, C., Wang, X., Young, R. L., Horowitz, M., Rayner, C. K., & Wu, T. (2018). Role of intestinal bitter sensing in enteroendocrine hormone secretion and metabolic control. Frontiers in Endocrinology, 9, 576-1-576-10.
DOI Scopus66 WoS59 Europe PMC43
2018 Wu, T., Rayner, C. K., Marathe, C. S., Jones, K. L., & Horowitz, M. (2018). Glucagon receptor signalling-backwards and forwards. Expert opinion on investigational drugs, 27(2), 135-138.
DOI Scopus7 WoS6 Europe PMC6
2018 Trahair, L., Wu, T., Feinle-Bisset, C., Marathe, C., Rayner, C., Horowitz, M., & Jones, K. (2018). Comparative effects of small intestinal glucose on blood pressure, heart rate, and noradrenaline responses in obese and healthy subjects. Physiological Reports, 6(4), e13610-1-e13610-8.
DOI WoS1 Europe PMC2
2018 Wu, T., Marathe, C. S., Horowitz, M., Jones, K. L., & Rayner, C. K. (2018). Comment on Russell-Jones et al. diabetes care 2017;40:943-950. Comment on bowering et al. diabetes care 2017;40:951-957. Diabetes Care, 41(3), e27-e28.
DOI Scopus1 WoS1
2018 Young, R., Lumsden, A., Martin, A., Schober, G., Pezos, N., Thazhath, S., . . . Keating, D. (2018). Augmented capacity for peripheral serotonin release in human obesity. International Journal of Obesity, 42(11), 1880-1889.
DOI Scopus80 WoS70 Europe PMC61
2018 Marathe, C., Rayner, C., Wu, T., Jones, K., & Horowitz, M. (2018). Gastric emptying and the personalized management of type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism, 103(9), 3503-3506.
DOI Scopus6 WoS6 Europe PMC6
2018 Pham, H. T., Stevens, J. E., Rigda, R. S., Phillips, L. K., Wu, T., Hausken, T., . . . Jones, K. L. (2018). Effects of intraduodenal administration of the artificial sweetener sucralose on blood pressure and superior mesenteric artery blood flow in healthy older subjects. American Journal of Clinical Nutrition, 108(1), 156-162.
DOI Scopus10 WoS10 Europe PMC10
2017 Rayner, C., Jones, K., Wu, T., & Horowitz, M. (2017). Gut feelings about diabetes and GLP-1 receptor agonists: lessons to be learnt from studies in functional gastrointestinal disorders. Diabetes, Obesity and Metabolism, 19(3), 309-312.
DOI Scopus8 WoS9 Europe PMC8
2017 Thazhath, S., Marathe, C. S., Wu, T., Chang, J., Khoo, J., Kuo, P., . . . Rayner, C. K. (2017). Acute effects of the glucagon-like peptide-1 receptor agonist, exenatide, on blood pressure and heart rate responses to intraduodenal glucose infusion in type 2 diabetes. Diabetes and Vascular Disease Research, 14(1), 59-63.
DOI Scopus16 WoS14 Europe PMC12
2017 Wu, T., Horowitz, M., & Rayner, C. K. (2017). New insights into the anti-diabetic actions of metformin: from the liver to the gut. Expert Review of Gastroenterology and Hepatology, 11(2), 157-166.
DOI Scopus56 WoS48 Europe PMC48
2017 Wu, T., Trahair, L., Little, T., Bound, M., Zhang, X., Wu, H., . . . Jones, K. (2017). Effects of vildagliptin and metformin on blood pressure and heart rate responses to small intestinal glucose in type 2 diabetes.. Diabetes Care, 40(5), 702-705.
DOI Scopus17 WoS17 Europe PMC10
2017 Wu, T., Rayner, C., Watson, L., Jones, K., Horowitz, M., & Little, T. (2017). Comparative effects of intraduodenal fat and glucose on the gut-incretin axis in healthy males. Peptides, 95, 124-127.
DOI Scopus18 WoS18 Europe PMC16
2017 Wu, T., Xie, C., Wu, H., Jones, K., Horowitz, M., & Rayner, C. (2017). Metformin reduces the rate of small intestinal glucose absorption in type 2 diabetes. Diabetes, Obesity and Metabolism, 19(2), 290-293.
DOI Scopus64 WoS61 Europe PMC59
2016 Wu, T., Rayner, C., & Horowitz, M. (2016). Inter-regulation of gastric emptying and incretin hormone secretion: implications for postprandial glycemic control. Biomarkers in Medicine, 10(11), 1167-1179.
DOI Scopus19 WoS17 Europe PMC14
2016 Rigda, R., Trahair, L., Little, T., Wu, T., Standfield, S., Feinle-Bisset, C., . . . Jones, K. (2016). Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects. Peptides, 86, 126-132.
DOI Scopus3 WoS3 Europe PMC3
2016 Thazhath, S., Marathe, C., Wu, T., Chang, J., Khoo, J., Kuo, P., . . . Rayner, C. (2016). The glucagon-like peptide 1 receptor agonist exenatide inhibits small intestinal motility, flow, transit, and absorption of glucose in healthy subjects and patients with type 2 diabetes: a randomized controlled trial. Diabetes, 65(1), 269-275.
DOI Scopus74 WoS72 Europe PMC67
2016 Zhang, X., Liu, T., Wang, Y., Zhong, M., Zhang, G., Liu, S., . . . Hu, S. (2016). Comparative Effects of Bile Diversion and Duodenal-Jejunal Bypass on Glucose and Lipid Metabolism in Male Diabetic Rats. Obesity Surgery, 26(7), 1565-1575.
DOI Scopus15 WoS11 Europe PMC12
2016 Thazhath, S., Wu, T., Bound, M., Checklin, H., Standfield, S., Jones, K., . . . Rayner, C. (2016). Administration of resveratrol for 5 wk has no effect on glucagon-like peptide 1 secretion, gastric emptying, or glycemic control in type 2 diabetes: a randomized controlled trial. American Journal of Clinical Nutrition, 103(1), 66-70.
DOI Scopus104 WoS102 Europe PMC86
2016 Thazhath, S., Wu, T., Bound, M., Checklin, H., Standfield, S., Jones, K., . . . Rayner, C. (2016). Effects of intraduodenal hydroxycitrate on glucose absorption, incretin release, and glycemia in response to intraduodenal glucose infusion in health and type 2 diabetes: a randomised controlled trial. Nutrition, 32(5), 553-559.
DOI Scopus10 WoS10 Europe PMC8
2016 Wu, T., Little, T., Bound, M., Borg, M., Zhang, X., Deacon, C., . . . Rayner, C. (2016). A protein preload enhances the glucose-lowering efficacy of vildagliptin in type 2 diabetes. Diabetes Care, 39(4), 511-517.
DOI Scopus91 WoS89 Europe PMC76
2016 Horowitz, M., Wu, T., Deane, A. M., Jones, K. L., & Rayner, C. K. (2016). DPP-4 inhibition and the known unknown. Diabetes, 65(8), 2124-2126.
DOI Scopus4 WoS4 Europe PMC4
2016 Wu, T., Zhang, X., Trahair, L., Bound, M., Little, T., Deacon, C., . . . Rayner, C. (2016). Small intestinal glucose delivery affects the lowering of blood glucose by acute vildagliptin in type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 101(12), 4769-4778.
DOI Scopus17 WoS17 Europe PMC15
2016 Chen, C., Hu, B., Wu, T., Zhang, Y., Xu, Y., Feng, Y., & Jiang, H. (2016). Bile acid profiles in diabetic (db/db) mice and their wild type littermates. Journal of Pharmaceutical and Biomedical Analysis, 131, 473-481.
DOI Scopus37 WoS34 Europe PMC27
2015 Yang, B., Lu, Y., He, J., Wu, T., Xie, Z., Lei, C., . . . Sun, Z. (2015). Performance of fasting plasma glucose and postprandial urine glucose in screening for diabetes in Chinese high‑risk population. Chinese Medical Journal, 128(24), 3270-3275.
DOI Scopus6 WoS6 Europe PMC4
2015 Wu, T., Thazhath, S., Marathe, C., Bound, M., Jones, K., Horowitz, M., & Rayner, C. (2015). Comparative effect of intraduodenal and intrajejunal glucose infusion on the gut-incretin axis response in healthy males. Nutrition and Diabetes, 5(5, article no. e156), e156-1-e156-4.
DOI Scopus47 WoS69 Europe PMC17
2015 Mignone, L., Wu, T., Horowitz, M., & Rayner, C. (2015). Whey protein: The "whey" forward for treatment of type 2 diabetes?. World Journal of Diabetes, 6(14), 1274-1284.
DOI Scopus9 WoS76 Europe PMC55
2015 Wu, T., Trahair, L., Bound, M., Deacon, C., Horowitz, M., Rayner, C., & Jones, K. (2015). Effects of sitagliptin on blood pressure and heart rate in response to intraduodenal glucose infusion in patients with Type 2 diabetes: a potential role for glucose-dependent insulinotropic polypeptide?. Diabetic Medicine, 32(5), 595-600.
DOI Scopus7 WoS6 Europe PMC5
2015 Okosun, I., Seale, J., & Lyn, R. (2015). Commingling effect of gynoid and android fat patterns on cardiometabolic dysregulation in normal weight American adults.. Nutrition & diabetes, 5(5), 1-8.
DOI Europe PMC63
2014 Thazhath, S., Wu, T., Bound, M., Checklin, H., Jones, K., Willoughby, S., . . . Rayner, C. (2014). Changes in meal composition and duration affect postprandial endothelial function in healthy humans. American Journal of Physiology. Gastrointestinal and Liver Physiology, 307(12), G1191-G1197.
DOI Scopus10 WoS10 Europe PMC8
2014 Wu, T., Thazhath, S., Bound, M., Jones, K., Horowitz, M., & Rayner, C. (2014). Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity?. Diabetes Research and Clinical Practice, 106(1), e3-e6.
DOI Scopus61 WoS58 Europe PMC54
2014 Wu, T., Ma, J., Bound, M., Checklin, H., Deacon, C., Jones, K., . . . Rayner, C. (2014). Effects of sitagliptin on glycemia, incretin hormones, and antropyloroduodenal motility in response to intraduodenal glucose infusion in healthy lean and obese humans and patients with type 2 diabetes treated with or without metformin. Diabetes, 63(8), 2776-2787.
DOI Scopus48 WoS48 Europe PMC41
2014 Thazhath, S., Wu, T., Young, R., Horowitz, M., & Rayner, C. (2014). Glucose absorption in small intestinal diseases. Expert Review of Gastroenterology and Hepatology, 8(3), 301-312.
DOI Scopus20 WoS17 Europe PMC16
2014 Li, F., Chen, B., Li, L., Zha, M., Zhou, S., Wu, T., . . . Sun, Z. (2014). INS-1 cells inhibit the production of extracellular matrix from pancreatic stellate cells. Journal of Molecular Histology, 45(3), 321-327.
DOI Scopus6 WoS6 Europe PMC4
2013 Wu, T., Bound, M., Standfield, S., Jones, K., Horowitz, M., & Rayner, C. (2013). Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans. Journal of Clinical Endocrinology and Metabolism, 98(4), 718-722.
DOI Scopus80 WoS74 Europe PMC68
2013 Wu, T., Bound, M., Standfield, S., Gedulin, B., Jones, K., Horowitz, M., & Rayner, C. (2013). Effects of rectal administration of taurocholic acid on glucagon-like peptide-1 and peptide YY secretion in healthy humans. Diabetes Obesity & Metabolism, 15(5), 474-477.
DOI Scopus116 WoS113 Europe PMC97
2013 Wu, T., Bound, M., Standfield, S., Bellon, M., Young, R., Jones, K., . . . Rayner, C. (2013). Artificial sweeteners have no effect on gastric emptying, glucagon-like peptide-1, or glycemia after oral glucose in healthy humans. Diabetes Care, 36(12), e202-e203.
DOI Scopus52 WoS52 Europe PMC47
2013 Wu, T., Rayner, C., Young, R., & Horowitz, M. (2013). Gut motility and enteroendocrine secretion. Current Opinion in Pharmacology, 13(6), 928-934.
DOI Scopus94 WoS81 Europe PMC66
2013 Chang, J., Wu, T., Greenfield, J., Samocha-Bonet, D., Horowitz, M., & Rayner, C. (2013). Effects of intraduodenal glutamine on incretin hormone and insulin release, the glycemic response to an intraduodenal glucose infusion, and antropyloroduodenal motility in health and type 2 diabetes. Diabetes Care, 36(8), 2262-2265.
DOI Scopus41 WoS39 Europe PMC36
2013 Young, R., Chia, C., Isaacs, N., Ma, J., Khoo, J., Wu, T., . . . Rayner, C. (2013). Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes. Diabetes, 62(10), 3532-3541.
DOI Scopus94 WoS85 Europe PMC71
2013 Wu, T., Bound, M., Zhao, R., Standfield, S., Bellon, M., Jones, K., . . . Rayner, C. (2013). Effects of a D-xylose preload with or without sitagliptin on gastric emptying, glucagon-like peptide-1, and postprandial glycemia in type 2 diabetes. Diabetes Care, 36(7), 1913-1918.
DOI Scopus53 WoS52 Europe PMC48
2012 Wu, T., Zhao, R., Bound, M., Checklin, H., Bellon, M., Little, T., . . . Rayner, C. (2012). Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans. American Journal of Clinical Nutrition, 95(1), 78-83.
DOI Scopus147 WoS138 Europe PMC111
2010 Wu, T., Rayner, C., Jones, K., & Horowitz, M. (2010). Dietary effects on incretin hormone secretion. Unknown Journal, 84, 81-110.
DOI Scopus47 WoS44 Europe PMC42

Year Citation
2019 Marathe, C. S., Rayner, C. K., Wu, T., Jones, K. L., & Horowitz, M. (2019). Diabetes and the Gastrointestinal Tract. In Encyclopedia of Gastroenterology, Second Edition (pp. 9-12). Elsevier.
DOI
2017 Watson, L., Wu, T., Horowitz, M., & Rayner, C. (2017). Whey Protein and Diabetes. In R. Watson, R. Collier, & V. Preedy (Eds.), Dairy in Human Health and Disease across the Lifespan (pp. 197-209). United Kingdom: Academic Press.
DOI Scopus3
2016 Wu, T., Rayner, C., & Horowitz, M. (2016). Incretins. In S. Herzig (Ed.), Metabolic Control (Vol. 233, pp. 137-171). Switzerland: Springer.
DOI Scopus58 Europe PMC40
2010 Wu, T., Rayner, C. K., Jones, K., & Horowitz, M. (2010). Dietary effects on incretin hormone secretion. In G. Litwack (Ed.), Source details - Title: Incretins and insulin secretion (pp. 81-110). US: Academic Press.
DOI

Year Citation
2025 Xie, C., Sun, Y., Huang, W., Bound, M., Grivell, J., Jones, K., . . . Wu, T. (2025). Acute administration of exogenous glucose-dependent insulinotropic polypeptide affects insulin secretion and sensitivity and cardiovascular function in type 2 diabetes. In DIABETOLOGIA Vol. 68 (pp. S410). SPRINGER.
2025 Sun, Y., Xie, C., Huang, W., Bound, M., Grivell, J., Jones, K., . . . Rayner, C. (2025). Interindividual variation in gastric emptying is dependent on the magnitude of the GLP-1 response to intestinal nutrients in healthy humans. In DIABETOLOGIA Vol. 68 (pp. S88). SPRINGER.
2025 Huang, W., Xie, C., Trico, D., Mari, A., Natali, A., Jones, K., . . . Wu, T. (2025). Endogenous glucose production during a 75g oral glucose load is associated with fasting serum serotonin in type 2 diabetes. In DIABETOLOGIA Vol. 68 (pp. S309). SPRINGER.
2025 Bannon, C., Walters, J., Wu, T., Kay, R., Spiller, R., Wilson, J., . . . Gribble, F. (2025). Insulin like peptide-5 is elevated in bile acid diarrhoea and is associated with a promotility role. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 37 (pp. 2 pages). WILEY.
2024 Sun, Y., Xie, C., Bound, M., Jones, K. L., Horowitz, M., Young, R., . . . Wu, T. (2024). Disparities in GLP-1 and GIP responses to small intestinal glucose infusion between people with well- and poorly-controlled type 2 diabetes. In DIABETOLOGIA Vol. 67 (pp. S92). SPAIN, Madrid: SPRINGER.
2024 Xie, C., Li, T., Bound, M., Grivell, J., Sun, Y., Jones, K. L., . . . Wu, T. (2024). Effects of well and poorly absorbed low-calorie sweeteners on insulin secretion and sensitivity in type 2 diabetes. In DIABETOLOGIA Vol. 67 (pp. S328). SPAIN, Madrid: SPRINGER.
2024 Huang, W., Xie, C., Xiang, C., Li, T., Young, R. L., Zhao, J., . . . Wu, T. (2024). A gut-on-a-chip platform to monitor GLP-1 secretion dynamics from primary intestinal tissue. In DIABETOLOGIA Vol. 67 (pp. S395). SPAIN, Madrid: SPRINGER.
2024 Xiang, C., Xie, C., Huang, W., Jones, K., Horowitz, M., Rayner, C., & Wu, T. (2024). Glucose-lowering by colesevelam in type 2 diabetes is related to a reduction in circulating serotonin. In DIABETOLOGIA Vol. 67 (pp. S125-S126). SPAIN, Madrid: SPRINGER.
2023 Sun, Y., Luo, Y., Xiang, C., Xie, C., Ma, J., Sun, Z., . . . Wu, T. (2023). Gastric emptying is accelerated in newly diagnosed type 2 diabetes patients, and is slowed with insulin pump therapy. In DIABETES RESEARCH AND CLINICAL PRACTICE Vol. 197 (pp. 1 page). ELSEVIER IRELAND LTD.
DOI
2023 Sun, Z., Wang, X., Yao, S., Wu, T., Zhu, H., Cheng, W., & Ben, S. (2023). EFFECT OF BASHAN DRINK, A VEGETABLE PLANT-BASED COMPOUND DRINK, ON BLOOD GLUCOSE IN TYPE 2 DIABETIC PATIENTS. In DIABETES TECHNOLOGY & THERAPEUTICS Vol. 25 (pp. A197). MARY ANN LIEBERT, INC.
2023 Bannon, C., Wilson, J. M., Verdino, P., Burling, K., Kay, R. G., Wu, T., . . . Gribble, F. (2023). DETERMINANTS OF PLASMA INSULIN-LIKE 5 LEVELS IN HUMANS AND EFFECT OF RECTAL BILE ACID EXPOSURE. In GASTROENTEROLOGY Vol. 164 (pp. S559). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC.
2022 Lu, A., Bound, M., Wu, T., Blefari, C., Horowitz, M., Rayner, C., & Jones, K. (2022). The effect of eight weeks' treatment with the short-acting GLP-1 agonist, lixisenatide, on postprandial blood pressure and heart rate in patients with type two diabetes - A secondary quantitative study. In INTERNAL MEDICINE JOURNAL Vol. 52 (pp. 39-40). WILEY.
2022 Lepore, A., Jenkins, A., Januszewski, A., Lange, K., Hatzinikolas, S., Jalleh, R., . . . Jones, K. (2022). Effect of the short-acting GLP-1 agonist, lixisenatide, on markers of inflammation and oxidative stress in health and type 2 diabetes. In INTERNAL MEDICINE JOURNAL Vol. 52 (pp. 20). WILEY.
2022 Li, T., Zhu, W., Sun, Z., Rayner, C., Young, R., & Wu, T. (2022). SGLT2 inhibition prevents high fat diet-induced glucose intolerance, but not weight gain, in C57BL/6 male mice. In DIABETOLOGIA Vol. 65 (pp. S257-S258). SPRINGER.
2022 Quast, D. R., Xie, C., Bound, M. J., Grivell, J., Jones, K. L., Horowitz, M., . . . Wu, T. (2022). Effects of acute and sub-chronic treatment with metformin on post-prandial blood pressure and heart rate in diet-controlled type 2 diabetes. In DIABETOLOGIA Vol. 65 (pp. S319-S320). Stockholm, SWEDEN: SPRINGER.
2022 Sang, M., Xie, C., Liu, Y., Qiu, S., Wang, X., Sun, Z., & Wu, T. (2022). Association between cholecystectomy and dysglycaemia: cross-sectional and prospective analyses. In DIABETOLOGIA Vol. 65 (pp. S181). SPRINGER.
2021 Li, T., Wu, T., & Sun, Z. (2021). Ectopic lipid deposition upregulates SGLT2 and GLUT1 in renal tubules. In DIABETOLOGIA Vol. 64 (pp. 215). SPRINGER.
2018 Borg, M. J., Rayner, C. K., Horowitz, M., Jones, K. L., & Wu, T. (2018). Metformin attenuates the fall in postprandial blood pressure and slows gastric emptying in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S112). Berlin, GERMANY: SPRINGER.
2018 Rayner, C. K., Watson, L. E., Phillips, L. K., Bound, M. J., Grivell, J., Wu, T., . . . Natali, A. (2018). Effects of sustained treatment with lixisenatide on gastric emptying and glucose metabolism in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S386-S387). GERMANY, Berlin: SPRINGER.
2018 Trahair, L. G., Nauck, M. A., Wu, T., Buttfield, M. D. M., Stevens, J. E., Hatzinikolas, S., . . . Jones, K. L. (2018). Measurement of gastric emptying using scintigraphy and a C-13-octanoic acid breath test with Wagner-Nelson analysis in type 2 diabetes. In DIABETOLOGIA Vol. 61 (pp. S338-S339). Berlin, GERMANY: SPRINGER.
WoS2
2015 Marathe, C., Thazhath, S. S., Wu, T., Horowitz., Jones, K. L., & Rayner, C. K. (2015). Effects of Glucagon-like peptide -1 (GLP-1) receptor agonist, exenatide, on small intestinal motility, and glucose absorption in health and type 2 diabetes. In Diabetes. Adelaide.
2015 Marathe, C., Thazhath, S. S., Wu, T., Horowitz, M., Jones, K. L., & Rayner, C. K. (2015). Effects of glucagon-like peptide -1 (GLP-1) receptor agonist, exenatide, on blood pressure and heart rate during duodenal glucose infusion in type 2 diabetes. In Diabetes. Adelaide.
2012 Bound, M., Wu, T., Gedulin, B., Horowitz, M., & Rayner, C. (2012). Effects of bile acid enemas on GLP-1 and PYY secretion in healthy humans. In Diabetologia Vol. 55 (pp. S338). Germany: Springer.
DOI
2012 Zhao, R., Wu, T., Jones, K., Horowitz, M., & Rayner, C. (2012). Effects of a D-xylose preload, with or without sitagliptin, on gastric emptying and postprandial glycaemia in patients with type 2 diabetes. In Journal of Gastroenterology and Hepatology Vol. 27 (pp. 148-149). Australia: Wiley-Blackwell.
DOI
2011 Wu, T., Zhao, B., Bound, M., Checklin, H. L., Bellon, M., Little, T. J., . . . Rayner, C. K. (2011). Effects of different sweet preloads on incretin hormone responses, gastric emptying and postprandial glycaemia in healthy humans. In DIABETOLOGIA Vol. 54 (pp. S330). Lisbon, PORTUGAL: SPRINGER.
2011 Young, R. L., Chia, B., Ma, J., Wu, T., Khoo, J., Horowitz, M., . . . Rayner, C. (2011). Disordered Control of Intestinal Sweet Taste Receptor Expression in Type 2 Diabetes. In GASTROENTEROLOGY Vol. 140 (pp. S99-S100). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC.
2010 Ma, J., Wu, T., Checklin, H. L., Wishart, J. M., Stevens, J., Jones, K. L., . . . Rayner, C. K. (2010). Effects of enterically coated, nutrient-containing pellets on glycaemia and incretin hormone release in type 2 diabetes. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 25 (pp. A114-A115). WILEY-BLACKWELL PUBLISHING, INC.
2010 Wu, T., Zhao, B., Bound, M., Checklin, H. L., Bellon, M., Little, T., . . . Rayner, C. K. (2010). Effects of sweet preloads on gastric emptying and postprandial glycaemia in healthy subjects. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 25 (pp. A105). WILEY-BLACKWELL PUBLISHING, INC.

Year Citation
2025 Xiang, C., Chen, C., Sun, Y., Luo, Y., Ma, J., Xie, C., . . . Wu, T. (2025). Serum bile acid response to an oral glucose load is exaggerated in newly diagnosed, treatment-naive, Chinese with type 2 diabetes and is reduced by insulin-pump therapy. Poster session presented at the meeting of Abstracts of the 61st EASD Annual Meeting of the European Association for the Study of Diabetes as published in Diabetologia. Germany: Springer.
DOI
2025 Borg, M. J., Xie, C., Chen, C., Huang, W., Jones, K., Horowitz, M., . . . Wu, T. (2025). Slowing of intestinal glucose absorption by metformin is not related to the timing of its administration. Poster session presented at the meeting of Abstracts of the 61st Annual Meeting of the European Association for the Study of Diabetes as published in Diabetologia. Germany: Springer.
DOI
2025 Kabthymer, R., Wu, T., Beigrezaei, S., Franco, O. H., Hodge, A. M., & de Courten, B. (2025). Longitudinal study on sweetened beverage consumption and risk of type 2 diabetes in Australia. Poster session presented at the meeting of Abstracts of the 61st Annual Meeting of the European Association for the Study of Diabetes as published in Diabetologia. Germany: Springer.
DOI
2024 Huang, W., Xie, C., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2024). Sex differences in the plasma glucagon responses to a high carbohydrate meal and a glucose drink in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 60th Annual Meeting of the European Association for the Study of Diabetes (EASD 2024), as published in Diabetologia. Madrid, Spain: Springer.
DOI
2024 Jalleh, R. J., Hatzinikolas, S., Slavotinek, A. C., Kamruzzaman, M., Lange, K., Malbert, C. H., . . . Jones, K. L. (2024). Effects of endogenous and exogenous glucose dependent insulinotropic polypeptide on blood pressure, heart rate, gastric emptying and blood glucose responses to oral glucose in healthy older people. Poster session presented at the meeting of Abstracts of the 60th EASD Annual Meeting of the European Association for the Study of Diabetes as published in Diabetologia. Madrid, Spain: Springer Nature.
DOI WoS1
2023 Chen, C., Zhang, D., Wu, T., & Zhang, H. (2023). Glucagon and insulin resistance in Chinese women with gestational diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Veedfald, S., Sun, Y., Xiang, C., Xie, C., Wu, T., Bound, M., . . . Rayner, C. K. (2023). Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 do not account for the entire incretin effect in healthy humans. Poster session presented at the meeting of Abstracts of the 59 th EASD Annual Meeting of the European Association for the Study of Diabetes, as published in Diabetologia. Hamburg, Germany: Springer.
DOI WoS1
2023 Horowitz, M., Xiang, C., Xie, C., Sun, Y., Jones, K. L., Rayner, C. K., . . . Wu, T. (2023). Gastric emptying is slower in women than men with type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Wu, T., Xie, C., Iroga, P., Bound, M., Grivell, J., Huang, W., . . . Rayner, C. (2023). The impact of timing of metformin administration on glycaemic and glucagon like peptide 1 responses to intraduodenal glucose in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Xiang, C., Sun, Y., Luo, Y., Xie, C., Huang, W., Sun, Z., . . . Wu, T. (2023). Gastric emptying of 75g oral glucose is predictive of the glycaemic response to mixed meals as well as oral glucose, but unrelated to antecedent glycaemia in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Quast, D. R., Lancaster, D., Xie, C., Bound, M. J., Grivell, J., Jones, K. L., . . . Nauck, M. A. (2023). Glucagon-like peptide 1 for lowering plasma glucose in hyperglycaemic subjects with type 2 diabetes: a systematic comparison of intravenous and subcutaneous routes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Huynh, L. Q., Hatzinikolas, S., Jalleh, R. J., Marathe, C. S., Wu, T., Malbert, C. -H., . . . Jones, K. L. (2023). Effect of exenatide once-weekly (QW) on the blood pressure and glycaemic responses to a mashed potato meal in type 2 diabetes: relationships to gastric emptying. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
WoS2
2023 Rayner, C. K., Huang, W., O'Hara, S. E., Xie, C., Nicholas, L. M., & Wu, T. (2023). Effects of a bitter tasting substance, denatonium benzoate, on pancreatic hormone secretion. Poster session presented at the meeting of Abstracts of the 59th Annual Meeting of the European Association for the Study of Diabetes (EASD 2023), as published in Diabetologia. Hamburg, Germany: Springer.
DOI
2023 Borg, M. J., Xie, C., Rayner, C., Horowitz, M., Jones, K., & Wu, T. (2023). Fasting plasma GIP is related to metabolic derangements in health and type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Sun, Z., Sang, M., Wang, P., Qiu, S., Wu, T., Wang, D., . . . Gu, Y. (2023). Association of serum and urinary ionome with dysglycaemia and diabetic complications. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Xie, C., Huang, W., Bound, M., Grivell, J., Jones, K., Horowitz, M., . . . Wu, T. (2023). Effect of intestinal exposure to endogenous bile acids on the incretin axis in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Li, T., Sang, M., Wang, J., Sun, Z., Xie, C., Rayner, C., . . . Wu, T. (2023). Tea consumption is associated with increased urinary glucose excretion, improved insulin resistance and reduced risk of dysglycaemia, in Chinese community-dwelling adults. Poster session presented at the meeting of DIABETOLOGIA. GERMANY, Hamburg: SPRINGER.
2023 Xie, C., Huang, W., Sun, Y., Horowitz, M., Jones, K., Rayner, C., & Wu, T. (2023). Disparities in blood glucose and incretin responses to intraduodenal glucose infusion in healthy young males and females. Poster session presented at the meeting of DIABETES RESEARCH AND CLINICAL PRACTICE. ELSEVIER IRELAND LTD.
DOI
2022 Xie, C., Jalleh, R. J., Huang, W., Sun, Y., Jones, K. L., Horowitz, M., . . . Wu, T. (2022). Determinants of blood glucose concentrations after a high carbohydrate meal in type 2 diabetes: a multiple linear regression analysis. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm & Online: Springer.
DOI
2022 Wu, T., Xie, C., Huang, W., Sun, Y., Horowitz, M., Jones, K. L., & Rayner, C. K. (2022). Disparities in blood glucose and incretin responses to intraduodenal glucose infusion in healthy young males and females. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm, Sweden & Online: Springer.
DOI
2022 Huang, W., Xie, C., Albrechtsen, N. J. W., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2022). The 'early' postprandial glucagon response to a mixed meal is dependent on the rate of gastric emptying in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 58th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Stockholm, Sweden & Online: Springer.
DOI
2021 Huang, W., Zhao, J., Nicholas, L. M., Shallan, A., Priest, C., Rayner, C. K., . . . Wu, T. (2021). An integrated microfluidic sensing system platform for dissecting insulin secretion and extracellular Ca²⁺ dynamics of pancreatic islets. Poster session presented at the meeting of Abstracts of the 57th EASD Annual Meeting of the European Association for the Study of Diabetes, as published in Diabetologia. Virtual: Springer.
DOI
2020 Wang, X., Chen, C., Xie, C., Horowitz, M., Jones, K. L., Rayner, C. K., . . . Wu, T. (2020). Serum bile acids after an oral glucose load in Chinese healthy individuals and patients with type 2 diabetes: relationships with glycaemia. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER.
2020 Xie, C., Wang, X., Bound, M. J., Young, R. L., Jones, K. L., Horowitz, M., . . . Wu, T. (2020). Bitter taste signalling modulates bile acid-induced PYY, but not GLP-1 secretion in healthy humans. Poster session presented at the meeting of Abstracts of the 56th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Virtual Online: Springer-Verlag.
DOI
2020 Wu, T., Xie, C., Wang, X., Bound, M. J., Grivell, J., Jones, K. L., . . . Rayner, C. K. (2020). Role of endogenous glucagon-like peptide-1 in the serum triglyceride response to intraduodenal fat infusion in type 2 diabetic patients on vildagliptin. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER.
2020 Sansome, D. J., Veedfald, S., Xie, C., Bound, M., Grivell, J., Jones, K. L., . . . Wu, T. (2020). Role of bile acids on glucose-lowering by metformin in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER.
2020 Huynh, L. Q., Ng, S., Xie, D., Hargreaves, M., Murthy, T. A., Wu, T., . . . Marathe, C. S. (2020). Diabetes distress is associated with gastrointestinal symptoms in type 1 diabetes. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER.
2020 Bizzotto, R., Rayner, C. K., Watson, L. E., Phillips, L. K., Lange, K., Bound, M. J., . . . Mari, A. (2020). Comparison of paracetamol absorption and gastric emptying measured by scintigraphy in relation to rate of appearance of oral glucose and postprandial glycaemia. Poster session presented at the meeting of DIABETOLOGIA. ELECTR NETWORK: SPRINGER.
2020 Wu, T., Wang, X., Xie, C., Marathe, C. S., Malbert, C. -H., Horowitz, M., . . . Sun, Z. (2020). Disparities in gastric emptying and postprandial glycaemia between Han Chinese and Caucasians with type 2 diabetes. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
2019 Jalleh, R. J., Pham, H. T., Marathe, C. S., Wu, T., Buttfield, M. D., Hatzinikolas, S., . . . Jones, K. L. (2019). Acute effects of lixisenatide on intragastric meal distribution: impact on energy intake. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
2019 Jones, K. L., Huynh, L. Q., Hatzinikolas, S., Rigda, R. S., Phillips, L., Pham, H. T., . . . Horowitz, M. (2019). Effect of exenatide once-weekly (QW) on gastric emptying in health: impact on glycaemia and glucose absorption. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
WoS1
2019 Huynh, L. Q., Pham, H. T., Holen, I. S., Hatzinikolas, S., Phillips, L., Wu, T., . . . Jones, K. L. (2019). Effects of a guar/whey preload on gastric emptying and glycaemic responses to oral glucose in healthy older people. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
2019 Xie, C., Wang, X., Bound, M. J., Grivell, J., Jones, K. L., Horowitz, M., . . . Wu, T. (2019). Roles of endogenous GLP-1 in the glycaemic and energy expenditure responses to fat in type 2 diabetes studied using vildagliptin and exendin(9-39). Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
2019 Marathe, C. S., Rigda, R. S., Buttfield, M., Hatzinikolas, S., Pham, H. T., Wu, T., . . . Jones, K. L. (2019). Acute administration of lixisenatide diminishes the insulin secretory response to oral glucose by slowing gastric emptying. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
2019 Marathe, J. A., Pham, H., Trahair, L., Huynh, L. Q., Wu, T., Rayner, C. K., . . . Marathe, C. S. (2019). Relationships between GIP and GLP-1 secretion in people with normal or impaired glucose tolerance. Poster session presented at the meeting of DIABETOLOGIA. Barcelona, SPAIN: SPRINGER.
2019 Horowitz, M., Xie, C., Wang, X., Bound, M. J., Grivell, J., Jones, K. L., . . . Wu, T. (2019). Comparative effects of intraduodenal glucose and fat on blood pressure and heart rate in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 55th Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Barcelona, SPAIN: Springer-Verlag.
DOI Europe PMC13
2019 Wu, T., Zhang, X., Horowitz, M., Jones, K. L., & Rayner, C. K. (2019). Comparative effects of proximal and distal small intestinal glucose exposure on blood pressure, heart rate and mesenteric blood flow in health and type 2 diabetes. Poster session presented at the meeting of Diabetologia. Barcelona, Spain: Springer.
2018 Veedfald, S., Wu, T., Bound, M., Grivell, J., Hartmann, B., Rehfeld, J. F., . . . Rayner, C. K. (2018). Hyperosmolar duodenal saline infusion lowers circulating ghrelin and stimulates intestinal hormone release in young men. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
2018 Wu, T., Borg, M., Jones, K. L., Horowitz, M., & Rayner, C. K. (2018). Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and GLP-1, and gastric emptying after oral glucose in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. Berlin, GERMANY: SPRINGER.
2018 Bitarafan, V., Fitzgerald, P., Little, T., Wu, T., Horowitz, M., & Feinle-Bisset, C. (2018). Effects of intraduodenal infusion of the bitter tastant, quinine, on antropyloroduodenal motility, plasma cholecystokinin concentrations and energy intake in humans. Poster session presented at the meeting of Abstracts of the 3rd meeting of the Federation of Neurogastroenterology and Motility (FNM 2018), as published in Neurogastroenterology & Motility. Amsterdam, The Netherlands: Wiley.
DOI
2018 Xie, C., Wang, X., Bound, M. J., Grivell, J., Young, R. L., Jones, K. L., . . . Wu, T. (2018). Effects of the bitter taste receptor agonist, denatonium benzoate, on postprandial glycaemia, gastric emptying and energy intake in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 54th Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI Europe PMC9
2018 Jones, K. L., Stevens, J. E., Buttfield, M., Wu, T., Hatzinikolas, S., Pham, H., . . . Horowitz, M. (2018). The reduction in postprandial glucose by sitagliptin is related to the rate of gastric emptying in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. Berlin, GERMANY: SPRINGER.
2018 Young, R. L., Kreuch, D., Mobegi, F. M., Leong, L., Schober, G., Isaacs, N. J., . . . Rogers, G. B. (2018). Low-calorie sweeteners disrupt the gut microbiome in healthy subjects in association with impaired glycaemic control. Poster session presented at the meeting of Abstracts of the 54th Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI
2017 Phillips, L., Watson, L., Wu, T., Bound, M., Checklin, H., Grivell, J., . . . Rayner, C. (2017). Longitudinal evaluation of gastric emptying in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI
2017 Jones, K., Rigda, R., Buttfield, M., Hatzinikolas, S., Pham, H., Marathe, C., . . . Horowitz, M. (2017). Acute effects of lixisenatide on gastric emptying, glycaemia and 'postprandial' blood pressure responses to an oral glucose load in healthy subjects and type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS1
2017 Young, R., Isaacs, N., Schober, G., Wu, T., Cvijanovic, N., Pezos, N., . . . Horowitz, M. (2017). Impact of artificial sweeteners on glycaemic control in healthy humans. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS4
2017 Rayner, C., Wu, T., Horowitz, M., & Jones, K. (2017). Blockade of glucagon-like peptide-1 receptors by exendin(9-39) attenuates the increase in heart rate during small intestinal glucose infusion in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS1
2017 Wu, T., Horowitz, M., Jones, K., & Rayner, C. (2017). Endogenous glucagon-like peptide-1 mediates the lowering of glycaemia during small intestinal glucose infusion by bile acids in type 2 diabetes. Poster session presented at the meeting of Abstracts of the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017), as published in Diabetologia. Berlin Heidelberg: Springer.
DOI WoS2
2017 Buttfield, M., Stevens, J., Hatzinikolas, S., Wu, T., Pham, H., Lange, K., . . . Jones, K. (2017). EFFECTS OF SITAGLIPTIN ON GASTRIC EMPTYING OF, AND THE BLOOD PRESSURE RESPONSE TO, A CARBOHYDRATE MEAL IN TYPE 2 DIABETES. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY.
2016 Chen, C., Hu, B., Wu, T., & Jiang, H. (2016). Targeted metabolomics study on bile acid profiles in db/db mice and their wild type littermates. Poster session presented at the meeting of DIABETOLOGIA. Munich, GERMANY: SPRINGER.
2016 Zhang, X., Bound, M., Standfield, S., Hu, S., Jones, K., Horowitz, M., . . . Wu, T. (2016). Comparative effects of proximal and distal small intestinal glucose on glycaemia, incretin hormone secretion and incretin effect in healthy males. Poster session presented at the meeting of Abstracts of the 52nd Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Munich, GERMANY: Springer-Verlag.
DOI WoS2
2016 Wu, T., Zhang, X., Little, T. L., Bound, M. J., Standfield, S., Deacon, C. F., . . . Rayner, C. K. (2016). The rate of intraduodenal glucose delivery affects the lowering of blood glucose by vildagliptin in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. Munich, GERMANY: SPRINGER.
2016 Mignone, L., Wu, T., Phillips, L., Bound, M., Checklin, H., Grivell, J., . . . Rayner, C. (2016). A whey/guar "preload" improves postprandial glycaemia and HbA(1c) in type 2 diabetes: a 12-week, single-blind, randomised and placebo controlled trial. Poster session presented at the meeting of Abstracts of the 52nd Annual Meeting of the European Association for the Study of Diabetes (EASD), as published in Diabetologia. Munich, GERMANY: Springer-Verlag.
DOI
2014 Mignone, L. E., Wu, T., Bound, M. J., Jones, K. L., Horowitz, M., & Rayner, C. K. (2014). A low-dose whey protein preload slows gastric emptying and improves post-prandial glycaemia in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER.
2014 Wu, T., Bound, M., Deacon, C., Jones, K., Horowitz, M., & Rayner, C. (2014). Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity?. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER.
2012 He, J., Sun, Z., Wu, T., Xie, Z., Lu, Y., Lei, C., . . . Zhou, Y. (2012). Screening for diabetes and pre-diabetes with combined use of FPG and quantitative postprandial urine glucose in Chinese high-risk population: a community-based study. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER.
2012 Wu, T., Zhao, B. R., Horowitz, M., Jones, K. L., & Rayner, C. K. (2012). Effects of a xylose preload, with or without sitagliptin, on gastric emptying and postprandial glycaemia in type 2 diabetes. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER.
2012 Young, R., Chia, B., Wu, T., Michael, H., & Rayner, C. (2012). Loss of intestinal sweet taste receptor control in type 2 diabetes: A risk factor for postprandial hyperglycemia?. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY-BLACKWELL.

Year Citation
2023 Zhou, X., Wu, T., Sang, M., Qiu, S., Wang, B., Guo, H., . . . Sun, Z. (2023). Variations in Blood Pressure Before and after 75 g Oral Glucose in Chinese Community-Dwelling Adults: Implications for the Detection of Both Hypertension and Postprandial Hypotension.
DOI

2023                           Diabetes Australia Project Grant (ID: Y23G-WUTO) ($70,000)

Project title: Harnessing bile acid sensing mechanisms to improve the management of type 2 diabetes.

Chief Investigators: Tongzhi Wu, Chris Rayner, Richard Young, Michael Horowitz, Karen Jones, Cong Xie, Heike Ependorff-Heidepriem, Weikun Huang.

 

2023                           Diabetes Australia Project Grant (ID: Y23G-RAYN) ($70,000)

Project title: Impact of renal 'sweet taste' sensing on the risk of dysglycaemia.

Chief Investigators: Chris Rayner, Tongzhi Wu, Richard Young, Merlin Thomas, Cong Xie, Weikun Huang.

 

2022 – 23                    Diabetes SA Project Grant. ($100,000)

Blocking intestinal sweet taste for better control of glycaemia in type 2 diabetes. Richard Young, Chris Rayner, Michael Horowitz, Tongzhi Wu, Kerry Ivey, Geraint Rogers.

 

2022 – 23                    Diabetes Australia Project Grant (ID: Y22G-YOUR). ($70,000)

Host or the hosted? Mechanisms underlying intestinal control of glycaemia in type 2 diabetes. Richard Young, Chris Rayner, Michael Horowitz, Tongzhi Wu, Geraint Rogers, Kerry Ivey.

 

2022 – 23                    Diabetes Australia Project Grant (ID: Y22G-JONK). ($70,000)

Effect of subcutaneous (sc) semaglutide on gastric emptying measured using the ‘gold standard’ technique, scintigraphy, in type 2 diabetes (T2D). Karen Jones, Michael Horowitz, Christ Rayner, Chinmay Marathe, Tongzhi Wu, Lee-ann Chapple.

 

2022                            Gum Bequest – Royal Adelaide Hospital ($40,000)

Project title: Effect of exenatide once weekly on gastric emptying of, and the postprandial glycaemic and cardiovascular responses to, a carbohydrate meal in type 2 diabetes. Karen Jones, Michael Horowitz, Chris Rayner, Tongzhi Wu, Chinmay Marathe.

 

2021                            University of Adelaide, Faculty of Health and Medical Sciences - 2021 Research Infrastructure Funding Award ($130,328)

 

Project title: LOGIQ E10 Ultrasound system – portable 3D ultrasound device and software. Karen Jones, Tongzhi Wu, Chris Rayner, Chinmay Marathe, Lee-ann Chapple, M Horowitz.

 

2021                            University of Adelaide, Faculty of Health and Medical Sciences - 2021 Small Equipment funding Award – Microfluidic perfusion pump ($2,470).

Tongzhi Wu, Richard Young, Lisa Nicholas, Weikun Huang.

 

2021                            University of Adelaide, Faculty of Health and Medical Sciences - 2021 Small Equipment funding Award – Refrigerated benchtop microcentrifuge ($5,999).

Lisa Nicholas, Sarah Roberston, Tongzhi Wu.

 

2021 – 22                    Diabetes Australia Project Grant (ID: Y21G-YOUR). ($60,000)

Project title: Blocking intestinal sweet taste for glycaemic benefits in type 2 diabetes. Richard Young, Geraint Rogers, Chris Rayner, Michael Horowitz, Tongzhi Wu.

 

2021 – 22                    Diabetes Australia Project Grant (ID: Y21G-WUTO). ($60,000)

Project Title: More or less? Bile acids and glycaemic control in type 2 diabetes. Tongzhi Wu, Chris Rayner, Karen Jones, Richard Young, Michael Horowitz.

 

2020 – 23                    The Hospital Research Foundation Mid-Career Fellowship ($600,000)

                                    Project title: Developing novel ‘gut-based’ therapies for type 2 diabetes

                                    Tongzhi Wu

 

2020 – 22                    Royal Adelaide Hospital Research Committee Clinical Project Grant ($48,286)

                                    Project title: GLP-1 for lowering plasma glucose in type 2 diabetes: A systemic comparison of intravenous and subcutaneous routes

                                    Chris Rayner, Daniel Quast, Tongzhi Wu

 

2020 – 22                    Royal Adelaide Hospital Research Committee Clinical Project Grant ($50,000)

                                    Project title: Effects of endogenous bile acids on postprandial glucose metabolism in both health and type 2 diabetes, and the impact of the small intestinal region exposed

                                    Tongzhi Wu, Chris Rayner, Liza Phillips, Karen Jones, Michael Horowitz

 

2020 – 22                    Diabetes Australia Project Grant (Y20G-YOUR) ($59,762)

                                    Project title: Does the gut microbiome link intake of low-calorie sweeteners to impaired blood glucose control?

                                    Richard Young, Geraint Rogers, Chris Rayner, Michael Horowitz, Tongzhi Wu

 

2020 – 22                    Diabetes Australia Project Grant (Y20G-WUTO) ($59,970)

                                    Project title: Effects of endogenous bile acids on postprandial glucose metabolism in type 2 diabetes, and the impact of the small intestinal region exposed

                                    Tongzhi Wu, Chris Rayner, Liza Phillips, Karen Jones, Michael Horowitz

 

2019 – 20                    Diabetes Australia Project Grant (Y19G-WUTO) ($59,991)

                                    Project title: Role of bile acids in glucose-lowering by metformin

                                    Tongzhi Wu, Chris Rayner, Karen Jones, Michael Horowitz

 

2019 – 20                    RAH Research Foundation Clinical Project Grant ($49,998)

Project title: Effects of acute and sub-acute treatment with metformin on cardiovascular responses to a glucose challenge in type 2 diabetes.

Tongzhi Wu, Liza Phillips, Chris Rayner, Karen Jones, Michael Horowitz

 

2019                            Diabetes Australia Project Grant (Y19G-JONK) ($59,872)

Project title: Effect of exenatide once weekly on gastric emptying of, and the postprandial glycaemic and cardiovascular responses to, an oral glucose load in type 2 diabetes.

Karen Jones, Liza Phillips, Tongzhi Wu, Chinmay Marathe, Michael Howoritz, Chris Rayner.

 

2018 – 22                    NHMRC Project Grant (APP1147333) ($725,276)

Project title: Bitter taste as a mediator of food intake and postprandial glycaemia in type 2 diabetes.

Tongzhi Wu, Chris Rayner, Karen Jones, Richard Young, Christine Feinle-Bisset

 

2018 – 22                    NSFC Project Grant (81870561) ($120,000)

                                    Project title: Effects of intestinal bitter taste sensing on gastrointestinal hormone secretion and glycaemic control

                                    Tongzhi Wu, Chris Rayner, Richard Young, Qin Lu, Dong Wang, Xuyi Wang, Juan Chen, Min Cai, Min Ge

 

2018 – 20                    RAH Research Foundation Florey Fellowship ($348,000)

Tongzhi Wu

 

2018 – 20                    Diabetes Australia Millennium Grant ($150,000)

Project title: Do artificial sweeteners affect glycaemic control in T2DM adversely?

Richard Young, Chris Rayner, Michael Horowitz, Tongzhi Wu

 

2018 – 19                    RAH Research Foundation Clinical Project Grant ($49,472)

Project title: Role of endogenous glucose-dependent insulinotropic polypeptide in the gastric emptying, glycaemia, splanchnic blood flow and blood pressure responses to oral glucose in healthy older subjects.

Karen Jones, Chris Rayner, Tongzhi Wu, Dylan Bartholomeusz, Michael Horowitz

 

2018 – 19                    RAH Research Foundation Clinical Project Grant ($49,710)

Project title: Molecular events linking artificial sweetener intake to augmented glucose absorption and dysglycaemia in health and type 2 diabetes.

Richard Young, Nam Nguyen, Chris Rayner, Tongzhi Wu, Dylan Bartholomeusz, Michael Horowitz

 

2017 – 19                    Investigator-initiated study funded by Novartis (CLAF237AAU09T) ($211,106)

                                    Defining the role of endogenous glucagon-like peptide-1 (GLP-1) in the glycaemic, triglyceride and energy expenditure responses to fat in patients with type 2 diabetes using Galvus (vildagliptin) and the GLP-1 receptor antagonist exendin(9-39). Tongzhi Wu

 

2017 – 18                    University of Adelaide Early Career Researcher Mentored Project Grant ($14,992)

Project title: Nutrient-gut interactions and glycaemic control in type 2 diabetes.

Tongzhi Wu

 

2017 – 18                    Project Development Grant of the NHMRC Centre of Research Excellence in Translating Nutritional Science to Good Health ($32,610)

                                    Project title: Stimulating intestinal bitter taste receptors for control of type 2 diabetes

Tongzhi Wu

 

2017 – 18                    Diabetes Australia Project Grant (Y17G-WUTO) ($59,270)

Project title: Gastrointestinal mechanisms of the anti-diabetic effect of metformin.

Tongzhi Wu, Chris Rayner, Michael Horowitz

 

2017                            University of Adelaide Research Infrastructure Awards ($26,410)

Project title: LOGIQ eR7 Ultrasound System to measure 2D and Doppler ultrasound in nutrition research.

Karen Jones, Chris Rayner Christine Feinle-Bisset, Tongzhi Wu, Stijn Soenen

 

2016 – 17                    RAH Research Foundation Clinical Project Grant ($49,258)

Project title: Does intestinal bitter taste sensing modulate gastrointestinal motility and hormone secretion to reduce glycaemia and energy intake in humans?

Tongzhi Wu, Chris Rayner

 

2015 – 17                    RAH Research Committee Mary Overton Early Career Fellowship ($252,000)

Project title: The “gut-incretin” axis in the regulation of postprandial glycaemia in type 2 diabetes

Tongzhi Wu

 

2015                            The University of Adelaide Interdisciplinary Seed Funding ($22,000)

Project title: Fibre insight in diabetes treatment: a new photonic fibre device to investigate the enteroendocrine L-cells.

Jiangbo Zhao, Tongzhi Wu

 

2014 – 16                    RAH Research Foundation Clinical Project Grant ($40,000)

Project title: Intestinal sweet taste receptor control of glucose absorption in human health & type 2 diabetes.

Richard Young, Tongzhi Wu, Chris Rayner

 

2014 – 16                    RAH Research Foundation Clinical Project Grant ($49,700)

Project title: Effects of DPP-4 inhibition with sitagliptin on postprandial blood pressure, glycaemia and incretin hormones in type 2 diabetes – relationship to gastric emptying.

Karen Jones, Tongzhi Wu, Chris Rayner

 

2014                            Clinical Research Fellowship of NHMRC Centre of Research Excellence in Translating Nutritional Science to Good Health ($80,571)

Project title: Gastrointestinal function and the management of type 2 diabetes

Tongzhi Wu

Date Role Research Topic Program Degree Type Student Load Student Name
2026 Principal Supervisor Optimising metformin administration for better glycaemic control in type 2 diabetes Doctor of Philosophy Doctorate Full Time Mr Amanuel Sisay Endeshaw
2025 Principal Supervisor The effects of low-calorie sweeteners on metabolic health in those with or without diabetes mellitus. Doctor of Philosophy Doctorate Full Time Mr Malcolm Joseph Borg
2025 Principal Supervisor The effects of low-calorie sweeteners on metabolic health in those with or without diabetes mellitus. Doctor of Philosophy Doctorate Full Time Mr Malcolm Joseph Borg
2022 Principal Supervisor Joint Award Project: Bile Acids and Glycaemia Control in Health and Type 2 Diabetes Doctor of Philosophy under a Jointly-awarded Degree Agreement with Doctorate Full Time Miss Yixuan Sun
2022 Principal Supervisor Joint Award Project: Bile Acids and Glycaemia Control in Health and Type 2 Diabetes Doctor of Philosophy Doctorate Full Time Miss Yixuan Sun

Date Role Research Topic Program Degree Type Student Load Student Name
2019 - 2023 Principal Supervisor Understanding intestinal and pancreatic hormone secretion in health and type 2 diabetes: (pre-)clinical studies and technical innovations Doctor of Philosophy Doctorate Full Time Dr Weikun Huang
2017 - 2021 Co-Supervisor The role of gastrointestinal function in the regulation of postprandial glycaemia and energy balance in health and type 2 diabetes Doctor of Philosophy Doctorate Full Time Mr Cong Xie
2017 - 2019 Co-Supervisor A microfluidic sensing system for simultaneous monitoring of extracellular Ca(II) and insulin secretion Master of Philosophy Master Full Time Dr Weikun Huang

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2021 - ongoing Principal Supervisor Taste receptor signalling and renal glucose excretion in health and diabetes The University of Adelaide/Southeast University - Doctorate Full Time Ting-ting Li
2020 - ongoing Principal Supervisor The role of bile acid-gut interaction in glucose homeostasis The University of Adelaide/Southeast University - Doctorate Full Time Chun-jie Xiang
2019 - ongoing Principal Supervisor Human gut-pancreas chip - a novel in vitro model for diabetes study The University of Adelaide - Higher Doctorate Full Time Weikun Huang
2019 - ongoing Principal Supervisor Interaction of intestinal bile acids with metformin The University of Adelaide - Honours Full Time Daniel Sansome
2017 - ongoing Principal Supervisor Effects of nutritive and non-nutritive compounds on gut function, appetite and blood glucose The University of Adelaide - Higher Doctorate Full Time Xuyi Wang
2017 - 2017 Principal Supervisor Gastrointestinal mechanisms of the anti-diabetic effect of metformin The University of Adelaide - Honours Full Time Malcolm Borg
2015 - ongoing Principal Supervisor Characterisation of glucose disposal mediated by different gut regions in health and type 2 diabetes The University of Adelaide - Doctorate Full Time Xiang Zhang

Date Topic Location Name
2022 - ongoing Role of bile acids in metabolic control The University of Adelaide Dr C Xie
2019 - ongoing Gastrointestinal actions of metformin Ruhr-University Bochum Dr D Quast
2019 - ongoing Gastrointestinal function in diabetes University of Copenhagen Dr S Veedfald
2017 - 2017 Gastrointestinal function in diabetes University of Copenhagen Dr S Veedfald
2015 - ongoing Gastrointestinal function in health and type 2 diabetes The University of Adelaide Dr C Marathe

Date Role Board name Institution name Country
2020 - ongoing Board Member Postgraduate Education The University of Adelaide Australia
2016 - ongoing Advisory Board Member The Global Institute of Traditional Medicine The University of Adelaide Australia

Date Role Committee Institution Country
2019 - ongoing Board Member Chinese Diabetes Society - Translational Research Group Chinese Diabetes Society China
2016 - ongoing Board Member Centre of Research Excellence in Nutrition Steering Committee The University of Adelaide Australia
2015 - ongoing Member Australian Diabetes Society - Australia
2009 - ongoing Member European Association for the Study of Diabetes - -

Date Role Editorial Board Name Institution Country
2023 - ongoing Board Member Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics Wiley-Blackwell United Kingdom
2022 - ongoing Editor Nutrients Nutrients Switzerland
2021 - 2022 Editor Frontiers in Physiology Frontiers Switzerland
2020 - ongoing Associate Editor Frontiers in Endocrinology Frontiers Switzerland

Date Event Name Event Type Institution Country
2022 - 2022 2022 International Diabetes Federation (IDF) Congress Conference International Diabetes Federation -
2022 - 2022 A Hundred Years with Glucagon and a Hundred more Conference Danish Diabetes Academy -
2020 - 2021 RAH Research Fund Campaign Social event Royal Adelaide Hospital -
2013 - ongoing Diabetes SA education sessions Seminars Diabetes SA -

Date Title Type Institution Country
2022 - 2023 MRFF Grant assessment Grant Assessment NHMRC -
2022 - 2022 NHMRC Ideas Grant Assessment Grant Assessment NHMRC -
2021 - 2023 NHMRC Ideas Grant Grant Assessment NHMRC -
2020 - ongoing Austrian Science Fund grant assessment Grant Assessment Austrian Science Fund -
2020 - ongoing New Zealand Health Research Council grant assessment Grant Assessment New Zealand Health Research Council -
2019 - ongoing National Natural Science Foundation of China grant assessment Grant Assessment National Nature Science Foundation of China -
2018 - ongoing French National Research Agency grant assessment Grant Assessment French National Research Agency -
2017 - ongoing Australiasian Diabetes Congress Conference Review Australian Diabetes Society -
2014 - ongoing Diabetes UK grant assessment Grant Assessment Diabetes UK -

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