Xanthe Venn

Dr Xanthe Venn

Senior Research Fellow

Future Industries Institute

Teaching Enterprise

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Available For Media Comment.

Dr Xanthe Venn is a Senior Research Fellow within the Regenerative Medicine Laboratories of the Future Industries Institute whose research is aimed at developing novel therapeutics for wound repair, reducing scar formation and understanding the mechanisms involved in tissue regeneration. Xanthe began her research into skin biology with Professor Cowin’s laboratory at the Women’s and Children’s Health Research Institute before the lab's move to UniSA in 2013. Xanthe was awarded her PhD from UniSA for her investigation of the role of the cytoskeletal protein Flightless I in tissue regeneration in 2016. Her current research is aimed at the development of a novel antibody based therapy to reduce inflammation and prevent scar formation in burn wounds and improve healing of chronic wounds suffered by diabetic patients. Xanthe is also working with materials scientists and physical chemists to develop novel wound dressings and investigate the use of low-temperature, atmospheric-pressure plasmas for biological and medical applications.
 

Year Citation
2023 Mokhtar, S. M. A., Derrick Roberts, A. L. K., Evans, D. R., & Strudwick, X. L. (2023). Cell viability assessment of PEDOT conducting polymer-coated microneedles for skin sampling. ACS Applied Bio Materials, 6(11), 4662-4671.
DOI Scopus7 WoS5 Europe PMC3
2023 Ajmal Mokhtar, S. M., Yamada, M., Prow, T. W., Moore, M., Strudwick, X. L., & Evans, D. (2023). PEDOT coated microneedle towards electrochemically assisted skin sampling. Journal of Materials Chemistry B, 11(22), 5021-5031.
DOI Scopus11 WoS11 Europe PMC4
2023 Strudwick, X. L., Whittle, J. D., Cowin, A. J., & Smith, L. E. (2023). Plasma-functionalised dressings for enhanced wound healing. International Journal of Molecular Sciences, 24(1, article no. 797), 1-13.
DOI Scopus4 WoS3 Europe PMC1
2023 Desire, C. T., Arrua, R. D., Strudwick, X. L., Kopecki, Z., Cowin, A. J., & Hilder, E. F. (2023). The development of microfluidic-based western blotting: Technical advances and future perspectives. Journal of Chromatography A, 1691(article no. 463813), 463813-1-463813-19.
DOI Scopus9 WoS7 Europe PMC7
2023 Ravindran Girija, A., Strudwick, X., Balasubramanian, S., Palaninathan, V., Nair, S. D., & Cowin, A. J. (2023). Collagen Functionalization of Polymeric Electrospun Scaffolds to Improve Integration into Full-Thickness Wounds.. Pharmaceutics, 15(3), 880.
DOI Scopus9 WoS9 Europe PMC5
2022 Ahangar, P., Strudwick, X. L., & Cowin, A. J. (2022). Wound Healing from an Actin Cytoskeletal Perspective. Cold Spring Harbor Perspectives in Biology, 14(8, article no. a041235), a041235-1-a041235-22.
DOI Scopus15 WoS14 Europe PMC9
2022 Sim, P., Strudwick, X. L., Song, Y., Cowin, A. J., & Garg, S. (2022). Influence of acidic pH on wound healing in vivo: a novel perspective for wound treatment. International Journal Of Molecular Sciences, 23(21), 1-15.
DOI Scopus162 WoS148 Europe PMC89
2021 Ahangar, P., Mills, S. J., Smith, L. E., Strudwick, X. L., Ting, A. E., Vaes, B., & Cowin, A. J. (2021). Treatment of murine partial thickness scald injuries with multipotent adult progenitor cells decreases inflammation and promotes angiogenesis leading to improved burn injury repair. Wound Repair Regen, 29(3), 1-10.
DOI Scopus1
2021 Haidari, H., Bright, R., Strudwick, X. L., Garg, S., Vasilev, K., Cowin, A. J., & Kopecki, Z. (2021). Multifunctional ultrasmall AgNP hydrogel accelerates healing of S. aureus infected wounds. Acta Biomaterialia, 128, 420-434.
DOI Scopus111 WoS104 Europe PMC69
2021 Yang, G. N., Ahangar, P., Strudwick, X. L., Kopecki, Z., & Cowin, A. J. (2021). Overexpression of Flii during murine embryonic development increases symmetrical division of epidermal progenitor cells. International Journal of Molecular Sciences, 22(15), 8235-1-8235-20.
DOI Scopus6 WoS6 Europe PMC6
2021 Yang, G. N., Strudwick, X. L., Bonder, C. S., Kopecki, Z., & Cowin, A. J. (2021). Increased expression of flightless I in cutaneous squamous cell carcinoma affects wnt/β-catenin signaling pathway. International Journal of Molecular Sciences, 22(24), 13203-1-13203-14.
DOI Scopus2 WoS1 Europe PMC3
2020 Yang, G. N., Strudwick, X. L., Bonder, C., Kopecki, Z., & Cowin, A. J. (2020). Effect of flightless I expression on epidermal stem cell niche during wound repair. Advances in Wound Care, 9(4), 161-173.
DOI Scopus11 WoS10 Europe PMC9
2020 Strudwick, X. L., Adams, D. H., Pyne, N. T., Samuel, M. S., Murray, R. Z., & Cowin, A. J. (2020). Systemic delivery of anti-integrin α L antibodies reduces early macrophage recruitment, inflammation, and scar formation in murine burn wounds. Advances in Wound Care, 9(12), 637-648.
DOI Scopus20 WoS19 Europe PMC13
2020 Ahangar, P., Mills, S. J., Smith, L. E., Strudwick, X. L., Ting, A. E., Vaes, B., & Cowin, A. J. (2020). Human multipotent adult progenitor cell-conditioned medium improves wound healing through modulating inflammation and angiogenesis in mice. Stem Cell Research and Therapy, 11(1), 299-1-299-16.
DOI Scopus30 WoS27 Europe PMC20
2020 Thomas, H. M., Ahangar, P., Hofma, B. R., Strudwick, X. L., Fitridge, R., Mills, S. J., & Cowin, A. J. (2020). Attenuation of flightless I increases human pericyte proliferation, migration and angiogenic functions and improves healing in murine diabetic wounds. International Journal of Molecular Sciences, 21(16), 1-15.
DOI Scopus14 WoS13 Europe PMC12
2020 Ravindran Girija, A., Palaninathan, V., Strudwick, X., Balasubramanian, S., Dasappan Nair, S., & Cowin, A. J. (2020). Collagen-functionalized electrospun smooth and porous polymeric scaffolds for the development of human skin-equivalent. RSC Advances, 10(45), 26594-26603.
DOI Scopus28 WoS28 Europe PMC20
2020 Strudwick, X. L., & Cowin, A. J. (2020). Multifunctional roles of the actin-binding protein Flightless I in inflammation, cancer and wound healing. Frontiers in Cell and Developmental Biology, 8(603508), 603508-1-603508-22.
DOI Scopus25 WoS25 Europe PMC21
2018 Fernandez, T., Strudwick, X. L., Al Bataineh, S., Short, R. D., Cowin, A. J., Whittle, J. D., & Smith, L. E. (2018). Surfaces to enhance matrix deposition for wound healing. Wound Practice and Research, 26(4), 201-209.
WoS1
2018 Bhatia, R., Strudwick, X., Cowin, A. J., & Szili, E. J. (2018). Investigation of helium plasma jet-treated serum and cell media on the viability of skin cells. Journal of Biomaterials and Tissue Engineering, 8(6), 892-899.
DOI WoS1
2017 Strudwick, X. L., Waters, J. M., & Cowin, A. J. (2017). Flightless I expression enhances murine claw regeneration following digit amputation. Journal of investigative dermatology, 137(1), 228-236.
DOI Scopus9 WoS8 Europe PMC7
2016 Oh, J., Strudwick, X., Short, R., Ogawa, K., Hatta, A., Furuta, H., . . . Szili, E. (2016). How plasma induced oxidation, oxygenation, and de-oxygenation influences viability of skin cells. Applied Physics Letters, 109(20), 203701-1-203701-5.
DOI Scopus31 WoS29
2016 Strudwick, X. L., Murray, R. Z., & Cowin, A. J. (2016). Development of an integrin-alpha L antibody therapy for reducing inflammation and scarring in burn wound injuries. Wound repair and regeneration, 24(6), 27.
2015 Strudwick, X. L., Lang, D. L., Smith, L. E., & Cowin, A. J. (2015). Combination of low calcium with Y-27632 rock Inhibitor increases the proliferative capacity, expansion potential and lifespan of primary human keratinocytes while retaining their capacity to differentiate into stratified epidermis in a 3D skin model. PLoS one, 10(4, article no. e0123651), 1-12.
DOI Scopus40 WoS35 Europe PMC30
2015 Martens, P., Ly, M., Adams, D., Penzkover, K., Strudwick, X., Cowin, A., & Poole-Warren, L. (2015). In vivo delivery of functional Flightless I siRNA using layer-by-layer polymer surface modification. Journal of Biomaterials Applications, 30(3), 257-268.
DOI Scopus9 WoS8 Europe PMC5
2012 Strudwick, X. L., & Cowin, A. J. (2012). Cytoskeletal regulation of dermal regeneration. Cells, 1(4), 1313-1327.
DOI Scopus10 Europe PMC9
2011 Kopecki, Z., Arkell, R., Strudwick, X., Hirose, M., Ludwig, R., Kern, J., . . . Cowin, A. (2011). Overexpression of the Flii gene increases dermal-epidermal blistering in an autoimmune ColVII mouse model of epidermolysis bullosa acquisita. Journal of Pathology, 225(3), 401-413.
DOI Scopus36 WoS37 Europe PMC31
2009 Adams, D., Ruzehaji, N., Strudwick, X., Greenwood, J., Campbell, H., Arkell, R., & Cowin, A. (2009). Attenuation of Flightless I, an actin-remodelling protein, improves burn injury repair via modulation of transforming growth factor (TGF)-beta 1 and TGF-beta 3. British Journal of Dermatology, 161(2), 326-336.
DOI Scopus45 WoS46 Europe PMC37
2009 Leitch, V., Strudwick, X., Matthaei, K., Dent, L., & Cowin, A. (2009). IL-5-overexpressing mice exhibit eosinophilia and altered wound healing through mechanisms involving prolonged inflammation. Immunology and Cell Biology, 87(2), 131-140.
DOI Scopus47 WoS44 Europe PMC40
2008 Adams, D., Studwick, X., Kopeki, Z., Hooper-Jones, J., Matthaei, K., Campbell, H., . . . Cowin, A. (2008). Gender specific effects on the actin-remodelling protein Flightless I and TGF-beta 1 contribute to impaired wound healing in aged skin. International Journal of Biochemistry & Cell Biology, 40(8), 1555-1569.
DOI Scopus28 WoS28 Europe PMC26
2008 Chan, H., Strudwick, X. L., Adams, D. H., Campbell, H. D., Powell, B. C., Arkell, R., & Cowin, A. J. (2008). Flightless I deficiency improves wound repair via mechanisms involving down-regulation of TGF-β1 gene expression and Smad signalling. WOUND REPAIR AND REGENERATION, 16(4), A64.
2007 Cowin, A., Adams, D., Strudwick, X., Chan, H., Hooper, J., Sander, G., . . . Campbell, H. (2007). Flightless I deficiency enhances wound repair by increasing cell migration and proliferation. Journal of Pathology, 211(5), 572-581.
DOI Scopus85 WoS83 Europe PMC74
2007 Kopecki, Z., Luchetti, M., Adams, D., Strudwick, X., Mantamadiotis, T., Stoppacciaro, A., . . . Cowin, A. (2007). Collagen loss and impaired wound healing is associated with c-Myb deficiency. Journal of Pathology, 211(3), 351-361.
DOI Scopus63 WoS61 Europe PMC52
2006 Strudwick, X., Powell, B., & Cowin, A. (2006). Role of sex hormones in acute and chronic would healing. Wound Practice & Research, 14(1), 35-38.
WoS5

Year Citation
2010 Poole-Warren, L. A., Martens, P., Ly, M., Adams, D., Riddle, K., Strudwick, X., & Cowin, A. J. (2010). RNA INTERFERENCE FOR MODULATION OF INFLAMMATORY RESPONSES TO IMPLANTABLE BIOMATERIALS. In WOUND REPAIR AND REGENERATION Vol. 18 (pp. A73). WILEY-BLACKWELL.
2008 Adams, D., Strudwick, X., Arkell, R., Campbell, H., & Cowin, A. J. (2008). Flightless I: A novel target for improving wound repair. In WOUND REPAIR AND REGENERATION Vol. 16 (pp. A60). BLACKWELL PUBLISHING.
2007 Adams, D. H., Strudwick, X. L., Hooper, J. A., Matthaei, K. I., Powell, B. C., Campbell, H. D., & Cowin, A. J. (2007). The actin-remodelling protein, Flightless I, is upregulated in response to aging and contributes to impaired wound healing. In WOUND REPAIR AND REGENERATION Vol. 15 (pp. A131). BLACKWELL PUBLISHING.
2007 Chan, H., Strudwick, X. L., Adams, D. H., Matthaei, K. I., Campbell, H. D., Powell, B. C., & Cowin, A. J. (2007). Flightless I deficiency improves wound repair via mechanisms involving down-regulation of TGFβ1 gene expression and Smad signalling. In WOUND REPAIR AND REGENERATION Vol. 15 (pp. A131). BLACKWELL PUBLISHING.
2007 Adams, D. H., Ruzehaji, N., Strudwick, X. L., Campbell, H. D., & Cowin, A. J. (2007). Flightless I defeciency accelerates burn injury repair. In WOUND REPAIR AND REGENERATION Vol. 15 (pp. A137). BLACKWELL PUBLISHING.

  • Development of alternative antimicrobial agents for the treatment of skin conditions to improve animal health and productivity, CRC SAAFE Limited, 26/07/2023 - 26/01/2027

  • AbRegen Flii Antibody Therapy, Argenx, 06/10/2025 - 06/10/2026

  • Plasma activated hydrogel therapy for combatting antimicrobial resistance in chronic wounds, NHMRC - Ideas Grants, 01/01/2021 - 31/12/2024

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Aidan Patterson
2024 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Matt Mack
2023 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Ruth Diana Simpson

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