Tod Fullston

• Appointments

  Date	Position	Institution name
  2016 - ongoing	Robinson Research Institute’s Career Development Fellow	University of Adelaide
  2012 - 2015	NHMRC Early Career Fellow	University of Adelaide
  2009 - 2011	Grant Funded Research Oficer	University of Adelaide
  2002 - 2005	Grant Funded Scientist	University of Adelaide
  2000 - 2002	Research Assistant	Novozymes (nee GroPep) Ltd Thebarton
  1999 - 2000	Research Assistant to Dr HE Richardson	University of Adelaide

• Education

  Date	Institution name	Country	Title
  2012	University of Adelaide	Australia	Doctor of Philosophy (PhD
  1999	University of Adelaide	Australia	Bachelor of Science (Hons)
  1998	University of Adelaide	Australia	Bachelor of Science (BSc)

• Journals

  Year	Citation
  2023	Penn, A., McPherson, N., Fullston, T., Arman, B., & Zander-Fox, D. (2023). Maternal high-fat diet changes DNA methylation in the early embryo by disrupting the TCA cycle intermediary alpha ketoglutarate. Reproduction, 165(4), 347-362. DOI Scopus6 WoS3 Europe PMC6
  2021	Schjenken, J. E., Moldenhauer, L. M., Sharkey, D. J., Chan, H. Y., Chin, P. Y., Fullston, T., . . . Robertson, S. A. (2021). High fat diet alters male seminal plasma composition to impair female immune adaptation for pregnancy in mice. Endocrinology, 162(10), 1-20. DOI Scopus27 WoS11 Europe PMC19
  2019	Mc Pherson, N. O., Shehadeh, H., Fullston, T., Zander-Fox, D., & Lane, M. (2019). Dietary micronutrient supplementation for 12 days in obese male mice restores sperm oxidative stress. Nutrients, 11(9), 1-18. DOI Scopus23 WoS15 Europe PMC15
  2019	Kedzior, S., Bianco-Miotto, T., Breen, J., Diener, K. R., Donnelley, M. W., Dunning, K. R., . . . Rumbold, A. R. (2019). It takes a community to conceive: an analysis of the scope, nature and accuracy of online sources of health information for couples trying to conceive. Reproductive Biomedicine and Society Online, 9, 48-63. DOI Scopus10 Europe PMC9
  2017	Robertson, S., Zhang, B., Chan, H., Sharkey, D., Barry, S., Fullston, T., & Schjenken, J. (2017). MicroRNA regulation of immune events at conception. Molecular Reproduction and Development, 84(9), 914-925. DOI Scopus23 WoS17 Europe PMC20
  2017	Fullston, T., Mc Pherson, N. O., Zander, D., & Lane, M. (2017). The most common vices of men can damage fertility and the health of the next generation. Journal of Endocrinology, 234(2), F1-F6. DOI Scopus28 WoS24 Europe PMC21
  2017	Coman, D., Fullston, T., Shoubridge, C., Leventer, R., Wong, F., Nazaretian, S., . . . McGillivray, G. (2017). X-Linked lissencephaly with absent corpus callosum and abnormal genitalia: an evolving multisystem syndrome with severe congenital intestinal diarrhea disease. Child Neurology o\Open, 4, 1-6. DOI Europe PMC3
  2017	Akison, L., Andraweera, P., Bertoldo, M., Brown, H., Cuffe, J., Fullston, T., . . . Schjenken, J. (2017). The current state of reproductive biology research in Australia and New Zealand: core themes from the Society for Reproductive Biology Annual Meeting, 2016. Reproduction, Fertility and Development, 29(10), 1883-1889. DOI Europe PMC1
  2017	McPherson, N., Lane, M., Sandeman, L., Owens, J., & Fullston, T. (2017). An exercise-only intervention in obese fathers restores glucose and insulin regulation in conjunction with the rescue of pancreatic islet cell morphology and microRNA expression in male offspring. Nutrients, 9(2), 122-1-122-17. DOI Scopus42 WoS36 Europe PMC13
  2016	Fullston, T., Ohlsson-Teague, E., Print, C., Sandeman, L., & Lane, M. (2016). Sperm microRNA content is altered in a mouse model of male obesity, but the same suite of microRNAs are not altered in offspring's sperm. PLoS One, 11(11), e0166076-1-e0166076-18. DOI Scopus76 WoS64 Europe PMC53
  2016	Dickinson, H., Moss, T., Gatford, K., Moritz, K., Akison, L., Fullston, T., . . . Morrison, J. (2016). A review of fundamental principles for animal models of DOHaD research: an Australian perspective. Journal of Developmental Origins of Health and Disease, 7(5), 449-472. DOI Scopus92 WoS84 Europe PMC69
  2016	Schjenken, J. E., Zhang, B., Chan, H. Y., Sharkey, D. J., Fullston, T., & Robertson, S. A. (2016). miRNA Regulation of Immune Tolerance in Early Pregnancy. American Journal of Reproductive Immunology, 75(3), 272-280. DOI Scopus46 WoS35 Europe PMC35
  2016	McPherson, N., Fullston, T., Kang, W., Sandeman, L., Corbett, M., Owens, J., & Lane, M. (2016). Paternal under-nutrition programs metabolic syndrome in offspring which can be reversed by antioxidant/vitamin food fortification in fathers. Scientific Reports, 6(1), 1-14. DOI Scopus58 WoS44 Europe PMC46
  2016	Fullston, T., & Evans, J. (2016). 'The Biggest Fertility Issue' in Special Issue 'Fertility in the 21st Century'. Australasian Science (Magazine), 37(1), 23-25.
  2015	McPherson, N., Bell, V., Zander-Fox, D., Fullston, T., Wu, L., Robker, R., & Lane, M. (2015). When two obese parents are worse than one! Impacts on embryo and fetal development. American Journal of Physiology: Endocrinology and Metabolism, 309(6), E568-E581. DOI Scopus60 WoS40 Europe PMC44
  2015	McPherson, N., Owens, J., Fullston, T., & Lane, M. (2015). Preconception diet or exercise interventions in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring. American journal of physiology: Endocrinology and metabolism, 308(9), E805-E821. DOI Scopus171 WoS131 Europe PMC109
  2015	Fullston, T., McPherson, N., Owens, J., Kang, W., Sandeman, L., & Lane, M. (2015). Paternal obesity induces metabolic and sperm disturbances in male offspring that are exacerbated by their exposure to an "obesogenic" diet. Physiological Reports, 3(3), e12336-1-e12336-14. DOI Scopus101 WoS84 Europe PMC73
  2015	Fullston, T., Shehadeh, H., Sandeman, L., Kang, W., Wu, L., Robker, R., . . . Lane, M. (2015). Female offspring sired by diet induced obese male mice display impaired blastocyst development with molecular alterations to their ovaries, oocytes and cumulus cells. Journal of Assisted Reproduction and Genetics, 32(5), 725-735. DOI Scopus25 WoS23 Europe PMC22
  2015	Zander-Fox, D., Fullston, T., McPherson, N., Sandeman, L., Kang, W., Good, S., . . . Lane, M. (2015). Reduction of mitochondrial function by FCCP during mouse cleavage stage embryo culture reduces birth weight and impairs the metabolic health of offspring. Biology of Reproduction, 92(5), 124-1-124-11. DOI Scopus18 WoS14 Europe PMC12
  2014	Lane, M., McPherson, N., Fullston, T., Spillane, M., Sandeman, L., Kang, W., & Zander-Fox, D. (2014). Oxidative stress in mouse sperm impairs embryo development, fetal growth and alters adiposity and glucose regulation in female offspring. PLoS One, 9(7), e100832-1-e100832-9. DOI Scopus105 WoS93 Europe PMC78
  2014	McPherson, N., Fullston, T., Aitken, R., & Lane, M. (2014). Paternal obesity, interventions, and mechanistic pathways to impaired health in offspring. Annals of Nutrition and Metabolism, 64(3-4), 231-238. DOI Scopus78 WoS68 Europe PMC65
  2014	McPherson, N., Fullston, T., Bakos, H., Setchell, B., & Lane, M. (2014). Obese father's metabolic state, adiposity, and reproductive capacity indicate son's reproductive health. Fertility and Sterility, 101(3), 865-873. DOI Scopus64 WoS49 Europe PMC43
  2013	Fullston, T., Ohlsson Teague, E., Mc Pherson, N., De Blasio, M., Mitchell, M., Corbett, M., . . . Lane, M. (2013). Paternal obesity initiates metablic disturbances in two generations of mice with incomplete penetrance to the F₂ generation and alters the transcriptional profile of testis and sperm microRNA content. FASEB Journal, 27(10), 4226-4243. DOI Scopus502 WoS390 Europe PMC355
  2012	Mc Pherson, N., Bakos, H., Fullston, T., & Lane, M. (2012). Impact of obesity on male fertility, sperm function and molecular composition. Spermatogenesis, 2(4), 253-263. DOI Europe PMC202
  2012	Fullston, T., Mc Pherson, N., Owens, J., Mitchell, M., Bakos, H., & Lane, M. (2012). Diet-induced paternal obesity in the absence of diabetes diminishes the reproductive health of two subsequent generations of mice. Human Reproduction, 27(5), 1391-1400. DOI Scopus173 WoS143 Europe PMC130
  2011	Mc Pherson, N., Fullston, T., Mitchell, M., Setchell, B., & Lane, M. (2011). SIRT6 in mouse spermatogenesis is modulated by diet-induced obesity. Reproduction Fertility and Development, 23(7), 929-939. DOI Scopus91 WoS71 Europe PMC63
  2011	Fullston, T., Gabb, B., Callen, D., Ullmann, R., Woollatt, E., Bain, S., . . . Gecz, J. (2011). Inherited Balanced Translocation t(9;17)(q33.2;q25.3) Concomitant With a 16p13.1 Duplication in a Patient With Schizophrenia. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 156(2), 204-214. DOI Scopus17 WoS13 Europe PMC13
  2011	Fullston, T., Finnis, M., Hackett, A., Hodgson, B., Brueton, L., Baynam, G., . . . Gecz, J. (2011). Screening and cell-based assessment of mutations in the Aristaless-related homeobox (ARX) gene. Clinical Genetics, 80(6), 510-522. DOI Scopus22 WoS21 Europe PMC20
  2011	Fullston, T., Mitchell, M., Wakefield, S., & Lane, M. (2011). Mitochondrial inhibition during preimplantation embryogenesis shifts the transcriptional profile of fetal mouse brain. Reproduction Fertility and Development, 23(5), 691-701. DOI Scopus9 WoS8 Europe PMC8
  2010	Whibley, A., Plagnol, V., Tarpey, P., Abidi, F., Fullston, T., Choma, M., . . . Raymond, F. (2010). Fine-scale survey of X chromosome copy number variants and indels underlying intellectual disability. American Journal of Human Genetics, 87(2), 173-188. DOI Scopus103 WoS93 Europe PMC92
  2010	Shoubridge, C., Fullston, T., & Gecz, J. (2010). ARX spectrum disorders: Making inroads into the molecular pathology. Human Mutation, 31(8), 889-900. DOI Scopus154 WoS125 Europe PMC110
  2010	White, R., Ho, G., Schmidt, S., Scheffer, I., Fischer, A., Yendle, S., . . . Christodoulou, J. (2010). Cyclin-dependent kinase-like 5 (CDKL5) mutation screening in Rett syndrome and related disorders. Twin Research and Human Genetics, 13(2), 168-178. DOI Scopus33 WoS28 Europe PMC23
  2010	Shoubridge, C., Tan, M., Fullston, T., Cloosterman, D., Coman, D., McGillivray, G., . . . Gecz, J. (2010). Mutations in the nuclear localization sequence of the Aristaless related homeobox; Sequestration of mutant ARX with IPO13 disrupts normal subcellular distribution of the transcription factor and retards cell division. Pathogenetics, 3(1), 1-15. DOI Scopus34 Europe PMC26
  2010	Fullston, T., Brueton, L., Willis, T., Philip, S., MacPherson, L., Finnis, M., . . . Morton, J. (2010). Ohtahara syndrome in a family with an ARX protein truncation mutation (c.81C>G/p.Y27X). European Journal of Human Genetics, 18(2), 157-162. DOI Scopus30 WoS25 Europe PMC21
  2009	Reish, O., Fullston, T., Regev, M., Heyman, E., & Gecz, J. (2009). A novel de novo 27 bp duplication of the ARX gene, resulting from postzygotic mosaicism and leading to three severely affected males in two generations. American Journal of Medical Genetics. Part A, 149A(8), 1655-1660. DOI Scopus16 WoS15 Europe PMC11
  2009	Demos, M., Fullston, T., Partington, M., Gecz, J., & Gibson, W. (2009). Clinical Study of Two Brothers With a Novel 33 bp Duplication in the ARX Gene. American Journal of Medical Genetics. Part A, 149A(7), 1482-1486. DOI Scopus16 WoS14 Europe PMC11
  2009	Tarpey, P., Smith, R., Pleasance, E., Whibley, A., Edkins, S., Hardy, C., . . . Stratton, M. (2009). A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. Nature Genetics, 41(5), 535-543. DOI Scopus513 WoS449 Europe PMC427
  2007	de Brouwer, A., Yntema, H., Kleefstra, T., Lugtenberg, D., Oudakker, A., de Vries, B., . . . Hamel, B. (2007). Mutation frequencies of X-linked mental retardation genes in families from the EuroMRX Consortium. Human Mutation, 28(2), 1-19. DOI WoS79 Europe PMC66
  2007	de Brouwer, A. P. M., Yntema, H. G., Kleefstra, T., Lugtenberg, D., Oudakker, A. R., de Vries, B. B. A., . . . Hamel, B. C. J. (2007). Mutation frequencies of X-linked mental retardation genes in families from the EuroMRX consortium.. Human Mutation, 28(2), 207-208. DOI Scopus92
  2006	Santos-Reboucas, C., Abdalla, C., Fullston, T., Campos Jr, M., Pimentel, M., & Gecz, J. (2006). Lack of FMR3 expression in a male with non-syndromic mental retardation and a microdeletion immediately distal to FRAXE CCG repeat. Neuroscience Letters, 397(3), 245-248. DOI Scopus6 WoS6 Europe PMC5

• Book Chapters

  Year	Citation
  2016	Fullston, T., Shehadeh, H., Schjenken, J. E., McPherson, N. O., Robertson, S. A., Zander-Fox, D., & Lane, M. (2016). Paternal obesity and programming of offspring health. In L. R. Green, & R. L. Hester (Eds.), Parental Obesity: Intergenerational Programming and Consequences (1 ed., pp. 105-131). New York, NY: Springer. DOI
  2015	Fullston, T., Wu, L., Teede, H., & Moran, L. (2015). Obesity and reproductive dysfunction in men and women. In R. Watson (Ed.), Handbook of fertility: Nutrition, diet, lifestyle and reproductive health (Vol. 11, 1 ed., pp. 119-132). Waltham, MA: Elsevier. DOI Scopus1

• Conference Papers

  Year	Citation
  2010	Raymond, L., Whibley, A. C., Plagnol, V., Tarpey, P. S., Abidi, F., Fullston, T., . . . Stratton, M. R. (2010). Fine-scale Survey of X Chromosome Copy Number Variants Underlying Intellectual Disability. In JOURNAL OF MEDICAL GENETICS Vol. 47 (pp. S36). Warwick, RI: B M J PUBLISHING GROUP.
  2010	Fullston, T., Mitchell, M., Owens, J., Palmer, N., Bakos, H., & Lane, M. (2010). Paternal Obesity Affects Male Offspring's Health and Sperm Function. In AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY Vol. 50 (pp. 22). WILEY-BLACKWELL PUBLISHING, INC. WoS2
  2009	Fullston, T., Mitchell, M., Wakefield, S., Filby, A., & Lane, M. (2009). Micro-Array Analysis of Fetal Mouse Brain Following Induction of Mitochondrial Dysfunction During Pre-Implantation Embryo Development.. In BIOLOGY OF REPRODUCTION (pp. 102). Pittsburgh, PA: SOC STUDY REPRODUCTION.
  2009	Shoubridge, C., Tan, M., Fullston, T., McGillivray, G., Mancini, G., & Gecz, J. (2009). Unravelling the pathogenesis of the ARX homeobox mutations; role of IPO13. In Proceedings of 59th Annual meeting of the American Society of Human Genetics (pp. 0 pages). USA: American Society of Human Genetics.

• Conference Items

  Year	Citation
  2014	Shehadeh, H., Fullston, T., Sandeman, L., Kang, W., & Lane, M. (2014). Paternal obesity impairs the reproductive health and ovarian molecular profile of their female offspring. Poster session presented at the meeting of HUMAN REPRODUCTION. Munich, GERMANY: OXFORD UNIV PRESS.
  2011	Owens, J. A., Fullston, T., Mitchell, M., Palmer, N., Bakos, H., & Lane, M. (2011). Diet Induced Paternal Obesity Impairs the Metabolic and Reproductive Health of Two Subsequent Generations. Poster session presented at the meeting of JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE. CAMBRIDGE UNIV PRESS.

Teaching, Supervision & Mentoring Roles

To date my HDR supervision includes 9 Honours students (3x primary; 6x co – 8 completions), co-supervised 3 PhD students (1 to completion), formally mentored a Jeffrey Robinson Honours Scholarship holder (2013) and informally mentored a further 4 ECRs, 9 PhD students and 7 Honours students.  7/8 of completed Honours students achieved the highest mark (IA).  Completed students currently hold roles as a NHRMC research fellow, research assistants, PhD students, or work in related clinical/biotech fields.  As part of the departments PhD annual review panel I assist PhD students to progress through their candidature (2012-15; 6-8 PhD students per year).  I have also supervised a total of 6 RAs to date. At the undergraduate level I have been involved in HRHII curriculum design, lectured/tutored HRHIII undergraduate students, supervised 2nd/3rd year Genetics/HRHIII and BHs (Adv) student lab placements (total of 6) and tutored/demonstrated to 1st year Science students.  From 2015-2016 I have also been formally mentoring 4 undergraduate BHs (Adv) students.

• Past Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2016 - 2021	External Supervisor	Metabolic disruptions in oocytes and embryos modifies DNA and histone methylation and alters embryonic development	Doctor of Philosophy	Doctorate	Full Time	Mr Alexander Penn
  2013 - 2014	Co-Supervisor	The effect of diet and exercise interventions for the treatment of male obesity induced sub fertility	Doctor of Philosophy	Doctorate	Full Time	Dr Nicole McPherson
  2013 - 2019	External Supervisor	The Effect of Dietary Micronutrient Supplementation on the Reproductive Health of Obese Males	Doctor of Philosophy	Doctorate	Full Time	Miss Helana Selange Shehadeh

• Committee Memberships

  Date	Role	Committee	Institution	Country
  2017 - 2019	Chair	Organising Committee	Epigenetics Consortium of South Australia (EpiCSA) Inc	Australia

• Email: tod.fullston@adelaide.edu.au