Toby Hughes

Associate Professor Toby Hughes

Associate Professor

Adelaide Dental School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


My primary research interest is identifying genes associated with dental development and oral health. Other interests include genotype x genotype interactions associated with oral micro-flora, functional genomics of oral development, and epigenetic modulation of gene expression.

I am currently involved in a number of research projects with common underlying themes.  One is modelling family data to establish the relative contributions of genes and environment to observed variation in features such as tooth size and spacing, cusp spacing, 3D surface morphology, arch shape, and occlusion. I have developed longitudinal models to identify common and unique genetic factors associated with the primary, mixed and permanent dentitions.

Another project is examining two closely related developmental events in Australian newborn twins - timing of emergence of the primary teeth and timing of colonisation of the oral cavity by Mutans streptococci, a primary agent in dental decay. Evidence suggests the prevalence of delayed tooth emergence is increasing in developed populations, presenting a smaller window of opportunity for colonisation and reducing the incidence of decay in primary teeth.

Both projects establish a baseline to develop models incorporating molecular data arising from the human genome project. We are planning to conduct genetic linkage and association analyses on data arising from both studies, to identify specific genes that contribute significantly to orofacial growth and development, and to oral health.

Date Project/ No. Investigators Funding Body Amount
2018 - Hughes School of Dentistry - RIBG $3,492
2018 SSP Hughes Faculty of Health Sciences - SSP $6,188
2018 - Hughes Faculty of Health Sciences - Travel Award $3,000
2018-2019 APP1147383 Hughes, Adler, Townsend, Bockmann National Health and Medical Research Council $284,652
2017 29-2016 Williams, Adler, Oshlack, Townsend, Hughes Australian Dental Research Foundation $10,920
2016-2017 161328 Hughes, Townsend, Adler, Bockmann Channel 7 Children's Research Foundation $75,000
2014-2016 APP1062911 Adler, Hughes, Townsend, Arora National Health and Medical Research Council $384,410
2015 03/2014 Ahmed, Ranjitkar, Anderson, Townsend, Hughes Australian Dental Research Foundation $5,000
2013-2016 1R01-DE19665 Hughes, Craig, Saffery, Townsend, Kilpatrick National Institutes of Health $644,189
2013 09/2012 Mihailidis, Hughes, Bockmann, Winning, Townsend Australian Dental Research Foundation $7,650
2013 08/2012 Tan, Townsend, Hughes, Sampson Australian Dental Research Foundation $2,394
2012 - Zilm, Fitzimmons, Marchant, Hughes et al School of Dentistry $5,000
2012 - Hughes, Fitzimmons, Zilm, Adler School of Dentistry $5,000
2012 37/2011 Odeh, Townsend, Mihailidis, Hughes, Lahdesmaki Australian Dental Research Foundation $4,827
2011-2013 APP1006294 Townsend, Seow, Hughes National Health and Medical Research Council $322,524
2011 - Zilm, Fitzimmons, Marchant, Hughes et al School of Dentistry $18,500
2011 - Coates, Bartold, Howe, Hughes University of South Australia $10,000
2011 62/2010 Gagliardi,Sampson, Townsend, Hughes Australian Dental Research Foundation $1,400
2011 70/2010 Ashar, Hughes, James, Townsend, Kaidonis Australian Dental Research Foundation $7,000
2010 640305 Fitzimmons, Hughes et al National Health and Medical Research Council $10,000
2010 - Mihailidis, Bockmann, Hughes, Seow, Townsend Australian Dental Industry Association $5,000
2010 26/2009 Ribeiro, Townsend, Sampson, Hughes, Brook Australian Dental Research Foundation $2,800
2010 28/2009 Mihailidis, Hughes, Bockmann, Winning, Townsend Australian Dental Research Foundation $3,340
2010 27/2009 Mihailidis, Bockmann, Hughes, Seow, Townsend Australian Dental Research Foundation $12,290
2010 32/2009 Hughes, Townsend Australian Dental Research Foundation $8,000
2009-2010 - Townsend, Hughes, Bockmann Financial Markets Foundation for Children $50,000
2008 - Hughes, Townsend School of Dentistry $5,220
2008 - Hughes, Townsend School of Dentistry $2,378
2008 49/2007 Hughes, Townsend Australian Dental Research Foundation $13,430
2007 ??/2006 Townsend, Seow, Gotjamanos, Hughes, Gully, Richards Australian Dental Research Foundation $3,000
2007 - Sanders, McNamara, Hughes, Slade, Bartold School of Dentistry $5,950
2007 - McNamara, Hughes School of Dentistry $4,760
2007 - Hughes, Bockmann, Townsend, Gully School of Dentistry $5,865
2007 - Hughes Faculty of Health Science $10,000
2006 - Hughes, Townsend School of Dentistry $2,000
2005-2007 APP349448 Townsend, Seow, Gotjamanos, Hughes, Gully, Richards National Health and Medical Research Council $514,150
2005-2006 - Hughes Faculty of Health Science $13,000
2003 - Townsend, Hughes, Apps Australian Dental Research Foundation $2,200
2002 - Townsend, Hughes, Race Australian Dental Research Foundation $2,200
2002 - Townsend, Hughes, Zaninovich Faculty of Health Science $1,400

Courses Developed and Taught

Bachelor of Dental Surgery

2012-present     Dental Science & Practice III (single stream program)

2011-present     Dental Science & Practice II (single stream program)

2010-present     Dental Science & Practice I (single stream program)

2007-2011         Dental Health Science III

2006-2009         Human Biology ID

1999-2010         Dental Health Science II

1999-2009         Dental Health Science I

Bachelor of Oral Health

2007-present     Human Biology IOH

  • Position: Associate Professor
  • Phone: 83133739
  • Email: toby.hughes@adelaide.edu.au
  • Campus: North Terrace
  • Building: Helen Mayo South, floor 3
  • Room: S3 31
  • Org Unit: Dental

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