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Dr Tina Bianco-Miotto

Tina Bianco-Miotto
Senior Lecturer
School of Agriculture, Food and Wine
Faculty of Sciences

I was appointed a Lecturer at the University of Adelaide in 2013, previous to which I held the W Bruce Hall Cancer Council SA Research Fellowship (2009-2012) and a NHMRC Peter Doherty Fellowship (2005-2009). My undergraduate and postgraduate studies have been undertaken at the University of Adelaide, with my PhD awarded in 2002. I have been a University of Adelaide Staff member since 2003. Since 2017 I have been appointed as a Senior Lecturer.

I am currently the Program Coordinator of the Bachelor of Applied Biology and I coordinate the courses: Principles & Practice of Science for App Biology I and Research Skills for Applied Biology II. I am also involved in teaching Foundations of Applied Biology and Nutrition III within the Bachelor of Food and Nutrition Science.

My research focus is on epigenetics and I have worked extensively with epigenetic mechanisms and methodologies and contributed to the understanding of the role of DNA methylation in leukaemia, colon, breast, ovarian and prostate cancers. More recently, I have focused on how environmental factors, such as diet, may perturb epigenetic modifications which may result in an increased susceptibility to diseases later in life. The focus of current research is to investigate how early life exposure to a high fat diet can impact disease risk later in life, investigations into the role of micronutrients and epigenetics in placental development and pregnancy, and finally the use of DNA methylation as biomarkers for predicting disease.

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Dr Tina Bianco-Miotto

I was appointed a Lecturer at the University of Adelaide in 2013, previous to which I held the W Bruce Hall Cancer Council SA Research Fellowship (2009-2012) and a NHMRC Peter Doherty Fellowship (2005-2009). My undergraduate and postgraduate studies have been undertaken at the University of Adelaide, with my PhD awarded in 2002. I have been a University of Adelaide Staff member since 2003. Since 2017 I have been appointed as a Senior Lecturer.

I am currently the Program Coordinator of the Bachelor of Applied Biology and I coordinate the courses: Principles & Practice of Science for App Biology I and Research Skills for Applied Biology II. I am also involved in teaching Foundations of Applied Biology and Nutrition III within the Bachelor of Food and Nutrition Science.

My research focus is on epigenetics and I have worked extensively with epigenetic mechanisms and methodologies and contributed to the understanding of the role of DNA methylation in leukaemia, colon, breast, ovarian and prostate cancers. More recently, I have focused on how environmental factors, such as diet, may perturb epigenetic modifications which may result in an increased susceptibility to diseases later in life. The focus of current research is to investigate how early life exposure to a high fat diet can impact disease risk later in life, investigations into the role of micronutrients and epigenetics in placental development and pregnancy, and finally the use of DNA methylation as biomarkers for predicting disease.

Eligible to supervise Masters and PhD — email supervisor to discuss availability.

Dr Bianco-Miotto was appointed a lecturer within the School of Agriculture, Food and Wine in March 2013 and is a member of the Robinson Research Institute, University of Adelaide. Previous to this, Dr Bianco-Miotto was the W Bruce Hall Cancer Council SA Research Fellow (2009-2012) and a NHMRC Peter Doherty Fellow (2005-2009). Dr Bianco-Miotto was a Director of the Australian Society for Medical Research (ASMR) (Nov 2012- Nov 2014) and Convenor of the 2014 Australian Health and Medical Research Congress. As of June 2015 she is the Chairperson and Co-founder of the Epigenetics Consortium of South Australia (EpiCSA) Incorporated. Dr Bianco-Miotto has worked extensively with epigenetic mechanisms and methodologies and has contributed to the understanding of the role of DNA methylation in several different cancers. More recently, she has focused on how environmental factors, such as diet, may perturb epigenetic modifications which may result in an increased susceptibility to diseases later in life.  Dr Bianco-Miotto has utilised numerous models in her research from rodent models including transgenic models, to human cells, tissue explants and clinical specimens. Dr Bianco-Miotto is currently working on identifying DNA methylation biomarkers for cancer diagnosis, as well as for predicting pregnancy complications. Her expertise in genetics, epigenetics and molecular biology have been applied to reserach projects ranging from pregnancy to cancer. Her focus is on environmental perturbations and how they contribute to future disease risk.

Appointments

Date Position Institution name
2017 Senior Lecturer (Level C) University of Adelaide
2013 - 2016 Lecturer (Level B) University of Adelaide
2009 - 2013 Cancer Council SA, W Bruce Hall Cancer Research Fellow (Level B) University of Adelaide
2007 - 2009 NHMRC Peter Doherty Fellow (Level B) University of Adelaide
2005 - 2006 NHMRC Peter Doherty Fellow (Level A) University of Adelaide
2003 - 2004 Postdoctoral Fellow (Level A) University of Adelaide
2002 - 2003 Research Officer Royal Adelaide Hospital

Education

Date Institution name Country Title
1998 - 2002 University of Adelaide Australia PhD
1997 - 1997 University of Adelaide Australia Bachelor of Health Sciences (Hons)
1993 - 1996 University of Adelaide Australia Bachelor of Science

Research Interests

Journals

Year Citation
2018 Wilson, R., Bianco-Miotto, T., Leemaqz, S., Grzeskowiak, L., Dekker, G., & Roberts, C. (2018). Early pregnancy maternal trace mineral status and the association with adverse pregnancy outcome in a cohort of Australian women. Journal of Trace Elements in Medicine and Biology, 46, 103-109.
DOI Scopus1
2018 Mayne, B., Shalem, L., Buckberry, S., Rodriguez Lopez, C., Roberts, C., Bianco-Miotto, T., & Breen, J. (2018). msgbsR: An R package for analysing methylation-sensitive restriction enzyme sequencing data. Scientific Reports, 8(1), 1-8.
DOI
2018 Grzeskowiak, L., Smithers, L., Grieger, J., Bianco-Miotto, T., Leemaqz, S., Clifton, V., . . . Roberts, C. (2018). Asthma treatment impacts time to pregnancy: evidence from the international SCOPE study. European Respiratory Journal, 51(2), 1702035-1-1702035-4.
DOI
2018 Ricciardelli, C., Bianco-Miotto, T., Jindal, S., Butler, L., Leung, S., McNeil, C., . . . Tilley, W. (2018). The Magnitude of Androgen Receptor Positivity in Breast Cancer is Critical for Reliable Prediction of Disease Outcome. Clinical cancer research : an official journal of the American Association for Cancer Research, 24(10), 2328-2341.
DOI
2018 Wilson, R., Gummow, J., McAninch, D., Bianco-Miotto, T., & Roberts, C. (2018). Vitamin and mineral supplementation in pregnancy: evidence to practice. Journal of Pharmacy Practice and Research, 48(2), 186-192.
DOI Scopus3
2018 Grieger, J. A., Grzeskowiak, L. E., Bianco-Miotto, T., Jankovic-Karasoulos, T., Moran, L. J., Wilson, R. L., . . . Roberts, C. T. (2018). Pre-pregnancy fast food and fruit intake is associated with time to pregnancy.. Human reproduction (Oxford, England).
DOI
2017 Wilson, R., Leemaqz, S., Goh, Z., McAninch, D., Jankovic-Karasoulos, T., Leghi, G., . . . Roberts, C. (2017). Zinc is a critical regulator of placental morphogenesis and maternal hemodynamics during pregnancy in mice. Scientific Reports, 7(1), 15137-1-15137-14.
DOI
2017 Buckberry, S., Bianco-Miotto, T., Bent, S., Clifton, V., Shoubridge, C., Shankar, K., & Roberts, C. (2017). Placental transcriptome co-expression analysis reveals conserved regulatory programs across gestation. BMC Genomics, 18(1), 10-1-10-13.
DOI Scopus2 WoS2 Europe PMC1
2017 Highet, A., Bianco-Miotto, T., Pringle, K., Peura, A., Bent, S., Zhang, J., . . . Roberts, C. (2017). A novel embryo culture media supplement that improves pregnancy rates in mice. Reproduction, 153(3), 327-340.
DOI Scopus1 WoS1 Europe PMC1
2017 Andraweera, P. H., Dekker, G. A., Arstall, M., Bianco-Miotto, T., & Roberts, C. T. (2017). Complications of pregnancy and future cardiovascular risk. Encyclopedia of Cardiovascular Research and Medicine.
2017 McAninch, D., Roberts, C., & Bianco-Miotto, T. (2017). Mechanistic insight into long noncoding RNAs and the placenta. International Journal of Molecular Sciences, 18(7), 1371-1-1371-16.
DOI WoS1 Europe PMC2
2017 Hodyl, N., Aboustate, N., Bianco-Miotto, T., Roberts, C., Clifton, V., & Stark, M. (2017). Child neurodevelopmental outcomes following preterm and term birth: what can the placenta tell us?. Placenta, 57, 79-86.
DOI Scopus1 WoS1
2017 Bianco-Miotto, T., Craig, J., Gasser, Y., van Dijk, S., & Ozanne, S. (2017). Epigenetics and DOHaD: from basics to birth and beyond. Journal of Developmental Origins of Health and Disease, 8(5), 513-519.
DOI Scopus6 WoS1 Europe PMC3
2017 De Matteo, R., Hodgson, D., Bianco-Miotto, T., Nguyen, V., Owens, J., Harding, R., . . . Gatford, K. (2017). Betamethasone-exposed preterm birth does not impair insulin action in adult sheep.. Journal of Endocrinol, 232(2), 175-187.
DOI Scopus1 WoS1 Europe PMC1
2017 Mayne, B., Leemaqz, S., Smith, A., Breen, J., Roberts, C., & Bianco-Miotto, T. (2017). Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation.. Epigenomics, 9(3), 279-289.
DOI Scopus5 WoS4 Europe PMC2
2016 Wilson, R., Grieger, J., Bianco-Miotto, T., & Roberts, C. (2016). Association between maternal zinc status, dietary zinc intake and pregnancy complications: a systematic review. Nutrients, 8(10), 1-28.
DOI Scopus5 WoS3
2016 Mayne, B., Bianco-Miotto, T., Buckberry, S., Breen, J., Clifton, V., Shoubridge, C., & Roberts, C. (2016). Large scale gene expression meta-analysis reveals tissue-specific, sex-biased gene expression in humans. Frontiers in Genetics, 7(OCT), 183-1-183-14.
DOI Scopus5 WoS5 Europe PMC5
2016 Hodyl, N., Roberts, C., & Bianco-Miotto, T. (2016). Cord blood DNA methylation biomarkers for predicting neurodevelopmental outcomes. Genes, 7(12), 117.
DOI Scopus4 WoS4 Europe PMC2
2016 Bianco-Miotto, T., Blundell, C., Buckberry, S., Chamley, L., Chong, S., Cottrell, E., . . . O'Tierney-Ginn, P. (2016). IFPA meeting 2015 workshop report I: placental mitochondrial function, transport systems and epigenetics. Placenta, 48, S3-S6.
DOI Scopus1 WoS1 Europe PMC1
2016 Bianco-Miotto, T., Mayne, B., Buckberry, S., Breen, J., Rodriguez Lopez, C., & Roberts, C. (2016). Recent progress towards understanding the role of DNA methylation in human placental development. Reproduction, 152(1), 23-30.
DOI Scopus11 WoS10 Europe PMC7
2016 Mayne, B., Leemaqz, S., Buckberry, S., Breen, J., Bianco-Miotto, T., & Roberts, C. (2016). Sex differences in the human placental methylome. CLINICAL ENDOCRINOLOGY, 84, 48.
2016 Highet, A., Buckberry, S., Mayne, B., Khoda, S., Bianco-Miotto, T., & Roberts, C. (2016). First trimester trophoblasts forming endothelial-like tubes in vitro emulate a ‘blood vessel development’ gene expression profile. Gene Expression Patterns, 21(2), 103-110.
DOI Scopus2 WoS2 Europe PMC2
2015 Buckberry, S., Spronk, F., Wilson, R., Laurence, J., Bianco-Miotto, T., Leemaqz, S., . . . Roberts, C. (2015). The effect of Vdr gene ablation on global gene expression in the mouse placenta. Genomics Data, 6, 72-73.
DOI Scopus1 Europe PMC1
2015 Highet, A., Khoda, S., Buckberry, S., Leemaqz, S., Bianco-Miotto, T., Harrington, E., . . . Roberts, C. (2015). Hypoxia induced HIF-1/HIF-2 activity alters trophoblast transcriptional regulation and promotes invasion. European Journal of Cell Biology, 94(12), 589-602.
DOI Scopus12 WoS9 Europe PMC6
2015 Wilson, R., Buckberry, S., Spronk, F., Laurence, J., Leemaqz, S., O'Leary, S., . . . Roberts, C. (2015). Vitamin D receptor gene ablation in the conceptus has limited effects on placental morphology, function and pregnancy outcome. PLoS One, 10(6), e0131287-1-e0131287-17.
DOI Scopus5 WoS3 Europe PMC3
2014 Buckberry, S., Bianco-Miotto, T., Bent, S., Dekker, G., & Roberts, C. (2014). Integrative transcriptome meta-analysis reveals widespread sex-biased gene expression at the human fetal-maternal interface. Molecular Human Reproduction, 20(8), 810-819.
DOI Scopus40 WoS37 Europe PMC33
2014 Buckberry, S., Bent, S., Bianco-Miotto, T., & Roberts, C. (2014). MassiR: A method for predicting the sex of samples in gene expression microarray datasets. Bioinformatics, 30(14), 2084-2085.
DOI Scopus6 WoS6 Europe PMC4
2014 Ochnik, A., Moore, N., Jankovic-Karasoulos, T., Bianco-Miotto, T., Ryan, N., Thomas, M., . . . Hickey, T. (2014). Antiandrogenic actions of medroxyprogesterone acetate on epithelial cells within normal human breast tissues cultured ex vivo. Menopause, 21(1), 79-88.
DOI Scopus8 WoS8 Europe PMC4
2014 Bianco-Miotto, T., Trotta, A., Need, E., Lee, A., Ochnik, A., Giorgio, L., . . . Buchanan, G. (2014). Molecular and structural basis of androgen receptor responses to dihydrotestosterone, medroxyprogesterone acetate and Delta(4)-tibolone. Molecular and Cellular Endocrinology, 382(2), 899-908.
DOI
2014 Buckberry, S., Bianco-Miotto, T., & Roberts, C. (2014). Imprinted and X-linked non-coding RNAs as potential regulators of human placental function. Epigenetics, 9(1), 81-89.
DOI Scopus15 WoS15 Europe PMC15
2014 Chiam, K., Ricciardelli, C., & Bianco-Miotto, T. (2014). Epigenetic biomarkers in prostate cancer: current and future uses. Cancer Letters, 342(2), 248-256.
DOI Scopus33 WoS31 Europe PMC27
2013 Day, T., & Bianco-Miotto, T. (2013). Common gene pathways and families altered by DNA methylation in breast and prostate cancers. Endocrine-Related Cancer, 20(5), 215-232.
DOI Scopus16 WoS16 Europe PMC14
2013 Andraweera, P., Dekker, G., Dissanayake, V., Bianco-Miotto, T., Jayasekara, R., & Roberts, C. (2013). Vascular endothelial growth factor family gene polymorphisms in preeclampsia in Sinhalese women in Sri-Lanka. The Journal of Maternal - Fetal & Neonatal Medicine, 26(5), 532-536.
DOI Scopus16 WoS15 Europe PMC9
2013 Chiam, K., Ryan, N., Ricciardelli, C., Day, T., Buchanan, G., Ochnik, A., . . . Bianco-Miotto, T. (2013). Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers. Prostate, 73(2), 182-193.
DOI Scopus10 WoS10 Europe PMC9
2012 Moore, N., Buchanan, G., Harris, J., Selth, L., Bianco-Miotto, T., Hanson, A., . . . Tilley, W. (2012). An androgen receptor mutation in the MDA-MB-453 cell line model of molecular apocrine breast cancer compromises receptor activity. Endocrine-Related Cancer, 19(4), 599-613.
DOI Scopus29 WoS27 Europe PMC22
2012 Thompson, V., Day, T., Bianco-Miotto, T., Selth, L., Han, G., Thomas, M., . . . Tilley, W. (2012). A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease. International Journal of Cancer, 131(3), 662-672.
DOI Scopus12 WoS13 Europe PMC11
2012 Buckberry, S., Bianco-Miotto, T., Hiendleder, S., & Roberts, C. (2012). Quantitative allele-specific expression and DNA methylation analysis of H19, IGF2 and IGF2R in the human placenta across gestation reveals H19 imprinting plasticity. PLoS One, 7(12), 1-11.
DOI Scopus15 WoS14 Europe PMC13
2011 Chiam, K., Centenera, M., Butler, L., Tilley, W., & Bianco-Miotto, T. (2011). GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells. PLoS One, 6(9), e25634-1-e25634-11.
DOI Scopus27 WoS21 Europe PMC22
2011 Buchanan, G., Need, E., Barrett, J., Bianco-Miotto, T., Thompson, V., Butler, L., . . . Coetzee, G. (2011). Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells. Molecular and Cellular Endocrinology, 342(1-2), 20-31.
DOI Scopus8 WoS8 Europe PMC8
2010 Bianco-Miotto, T., Chiam, K., Buchanan, G., Jindal, S., Day, T., Thomas, M., . . . Ricciardelli, C. (2010). Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development. Cancer Epidemiology Biomarkers & Prevention, 19(10), 2611-2622.
DOI Scopus66 WoS51 Europe PMC38
2010 Ricciardelli, C., Bianco-Miotto, T., Jindal, S., Dodd, T., Cohen, P., Marshall, V., . . . Horsfall, D. (2010). Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies. Cancer Epidemiology Biomarkers & Prevention, 19(7), 1755-1765.
DOI Scopus8 WoS8 Europe PMC6
2010 Ochnik, A. M., Jankovic-Karasoulos, T., Cops, E. J., Birrell, S. N., Butler, L. M., Jindall, S., . . . Hickey, T. E. (2010). Medroxyprogesterone acetate impedes 5 alpha-dihydrotesterone induced androgen receptor signaling in normal and malignant human breast epithelial cells. CANCER RESEARCH, 70(8 Supplement), 4 pages.
DOI
2009 Chiam, K., Jindal, S., Ryan, N., Moretta, S., De Blasio, M., Kind, K., . . . Bianco-Miotto, T. (2009). 166. MATERNAL OBESITY IS ASSOCIATED WITH AN INCREASED INCIDENCE OF PROSTATE ABNORMALITIES IN ADULT RAT OFFSPRING. Reproduction, Fertility and Development, 21(9), 84.
DOI
2009 Butler, L., Centenera, M., Marrocco, D., Carter, S., Bianco-Miotto, T., & Tilley, W. (2009). A novel combinatorial approach using androgen receptor-targeted agents for treatment of prostate cancer. CANCER RESEARCH, 69, 2 pages.
2009 Peters, A., Buchanan, G., Ricciardelli, C., Bianco-Miotto, T., Centenera, M., Harris, J., . . . Tilley, W. (2009). Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer. Cancer Research, 69(15), 6131-6140.
DOI Scopus186 WoS183 Europe PMC128
2009 Bianco-Miotto, T., Hussey, D., Day, T., O'Keefe, D., & Dobrovic, A. (2009). DNA methylation of the ABO promoter underlies loss of ABO allelic expression in a significant proportion of leukemic patients. PLoS One, 4(3), 1-8.
DOI Scopus24 WoS20 Europe PMC15
2009 Chiam, K., Tilley, W., Butler, L., & Bianco-Miotto, T. (2009). The dynamic and static modification of the epigenome by hormones: A role in the developmental origin of hormone related cancers. Biochimica et Biophysica Acta-Reviews on Cancer, 1795(2), 104-109.
DOI Scopus9 WoS11 Europe PMC9
2008 Cops, E., Bianco-Miotto, T., Moore, N., Clarke, C., Birrell, S., Butler, L., & Tilley, W. (2008). Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors. Journal of Steroid Biochemistry and Molecular Biology, 110(3-5), 236-243.
DOI Scopus39 WoS38 Europe PMC26
2007 Marrocco, D., Tilley, W., Bianco-Miotto, T., Evdokiou, A., Scher, H., Rifkind, R., . . . Butler, L. (2007). Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation. Molecular Cancer Therapeutics, 6(1), 51-60.
DOI Scopus73 WoS68 Europe PMC57
2005 Buchanan, G., Birrell, S., Peters, A., Bianco-Miotto, T., Ramsay, K., Cops, E., . . . Tilley, W. (2005). Decreased androgen receptor levels and receptor function in breast cancer contribute to the failure of response to medroxyprogesterone acetate. Cancer Research, 65(18), 8487-8496.
DOI Scopus52 WoS50 Europe PMC39
2003 Smith, E., Bianco-Miotto, T., Drew, P., & Watson, D. (2003). Method for optimizing methylation-specific PCR. Biotechniques, 35(1), 32-33.
Scopus5 WoS4 Europe PMC3
2002 Tan, L., Bianco-Miotto, T., & Dobrovic, A. (2002). Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer. Carcinogenesis, 23(2), 231-236.
DOI Scopus63 WoS60 Europe PMC38
2002 Dobrovic, A., Bianco-Miotto, T., Tan, L., Sanders, T., & Hussey, D. (2002). Screening for and analysis of methylation differences using methylation-sensitive single-strand conformation analysis. Methods-A Companion to Methods in Enzymology, 27(2), 134-138.
DOI Scopus18 WoS16 Europe PMC8
2001 Bianco-Miotto, T., Farmer, B., Sage, R., & Dobrovic, A. (2001). Loss of red cell A, B, and H antigens is frequent in myeloid malignancies. Blood, 97(11), 3633-3639.
DOI Scopus49 WoS38 Europe PMC27
2000 Bianco-Miotto, T., Chenevix-Trench, G., Walsh, D., Cooper, J., & Dobrovic, A. (2000). Tumour-specific distribution of BRCAI promoter region methylation supports a pathogenetic role in breast and ovarian cancer. Carcinogenesis, 21(2), 147-151.
DOI Scopus95 WoS89 Europe PMC59
2000 Butler, L., Dobrovic, A., Bianco-Miotto, T., & Cowled, P. (2000). Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma. British Journal of Cancer, 82(1), 131-135.
DOI Scopus18 WoS15 Europe PMC18
1999 Bianco-Miotto, T., Hussey, D., & Dobrovic, A. (1999). Methylation-sensitive, single-strand conformation analysis (MS-SSCA): A rapid method to screen for and analyze methylation.. Human Mutation, 14(4), 289-293.
DOI Scopus44 WoS41 Europe PMC20

Book Chapters

Conference Papers

Year Citation
2017 Wilson, R. L., Jankovic-Karasoulous, T., McAninch, D., Roberts, C. T., & Bianco-Miotto, T. (2017). IMMUNOLOCALISATION OF 5-METHYLCYTOSINE AND 5HYDROXYMETHYLCYTOSINE IN THE PLACENTA ACROSS GESTATION REVEALS DYNAMIC CO -LOCALISATION OF EXPRESSION. In PLACENTA Vol. 57 (pp. 260-261). Manchester, ENGLAND: W B SAUNDERS CO LTD.
DOI
2016 Wilson, R., Leemaqz, S., Goh, Z., McAninch, D., Jankovic-Karasoulos, T., Bianco-Miotto, T., & Roberts, C. (2016). ZINC DEFICIENCY ALTERS PLACENTAL DEVELOPMENT AND MATERNAL HEMODYNAMICS CONTRIBUTING TO FETAL GROWTH RESTRICTION IN MICE. In PLACENTA Vol. 45 (pp. 80). Portland, OR: W B SAUNDERS CO LTD.
DOI
2015 Bianco-Miotto, T., Lopez, C. R., Leemaqz, S., Buckberry, S., McCullough, D., Zhuang, Z., . . . Roberts, C. (2015). DNA METHYLATION BIOMARKERS FOR PREDICTING PREGNANCY COMPLICATIONS. In PLACENTA Vol. 36 (pp. A38-A39). W B SAUNDERS CO LTD.
DOI WoS1
2008 Hickey, T., Ocknik, A., Bianco-Miotto, T., Birrell, S., Butler, L., & Tilley, W. (2008). Functional androgen signaling in an explant model of normal human breast tissue. In BIOLOGY OF REPRODUCTION Vol. 78 (pp. 142). Kona, HI: SOC STUDY REPRODUCTION.
DOI
2006 Murphy, N., Bianco-Miotto, T., Ricciardelli, C., Ruiz, A., Segara, D., McNeil, C., . . . Tilley, W. (2006). Expression of the androgen receptor and its association with disease outcome in breast cancer.. In BREAST CANCER RESEARCH AND TREATMENT Vol. 100 (pp. S262-S263). San Antonio, TX: SPRINGER.

Conference Items

Year Citation
2015 Bianco-Miotto., Rodriguez Lopez., Leemaqz., Zhuang, Z., McCullough., Dekker., . . . Roberts, C. (2015). Predicting Pregnancy Complications from Maternal Buffy Coat DNA at 15 Weeks Gestation. Poster session presented at the meeting of Endocrine Society of Australia (ESA) and Society for Reproductive Biology (SRB) Annual Scientific Meeting. Adelaide, Australia.
2015 Highet, A., Khoda, S., Buckberry, S., Bianco-Miotto, T., & Roberts, C. (2015). ANGIOGENESIS-ASSOCIATED PATHWAYS IN TROPHOBLAST PSEUDOVASCULOGENESIS. Poster session presented at the meeting of PLACENTA. W B SAUNDERS CO LTD.
DOI
2015 Buckberry, S., Bianco-Miotto, T., Bent, S., Dekker, G., & Roberts, C. (2015). INTEGRATIVE ANALYSIS OF PLACENTAL TRANSCRIPTOME ORGANIZATION REVEALS HIGHLY CONSERVED REGULATORY PROGRAMS AND POINTS TOWARD A PREECLAMPSIA GENE CLUSTER. Poster session presented at the meeting of PLACENTA. W B SAUNDERS CO LTD.
DOI
2014 Zhuang., Rodriguez Lopez., Chiam, K., Harryanto, H., Ryan, N. K., Jindal, S., . . . Bianco-Miotto. (2014). A high fat diet early in life and prostate cancer risk. Poster session presented at the meeting of The Australian Health and Medical Research Congress. Melbourne, Australia.
2014 Gafford, K. L., Liu, H., Ahmad, Z., De Blasio, M. J., Heinemann, G. K., Bianco-Miotto, T., & Owens, J. A. (2014). Restriction of Placental Growth Increases Plasticity of Insulin Secretion in Response to Hyperglycemic Challenge in Adult Sheep. Poster session presented at the meeting of ENDOCRINE REVIEWS. ENDOCRINE SOC.
2014 Gafford, K. L., Liu, H., Ahmad, Z., De Blasio, M. J., Heinemann, G. K., Bianco-Miotto, T., & Owens, J. A. (2014). Restriction of Placental Growth Increases Plasticity of Insulin Secretion in Response to Hyperglycemic Challenge in Adult Sheep. Poster session presented at the meeting of ENDOCRINE REVIEWS. ENDOCRINE SOC.
2014 Roberts, C., Leemaqz, S., Bianco-Miotto, T., Andraweera, P., Zhou, A., McCowan, L., & Dekker, G. (2014). HOW BIG IS BIG ENOUGH? POPULATION DIFFERENCES IN PREGNANCY OUTCOME. Poster session presented at the meeting of PLACENTA. Paris, FRANCE: W B SAUNDERS CO LTD.
DOI
2011 Bianco-Miotto, T., Chiam, K., Jindal, S., Ryan, N., Zulkifli, S., Moretta, S., . . . Owens, J. (2011). Early Life Exposure to a High Fat Diet Results in Histological and Molecular Changes in the Rat Prostate Which Are Transmitted Paternally to the Second Generation. Poster session presented at the meeting of JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE. CAMBRIDGE UNIV PRESS.
2011 Bianco-Miotto, T., Chiam, K., Jindal, S., Ryan, N. K., Zulkifli, S., Moretta, S., . . . Owens, J. A. (2011). Exposure to a high fat diet results in histological and molecular changes in the rat prostate. Poster session presented at the meeting of Obesity Research & Clinical Practice.
DOI
2000 Tan, L. W., Bianco-Miotto, T., & Dobrovic, A. (2000). Connexin-26 is methylated in a high proportion of breast cancer patients. Poster session presented at the meeting of Unknown Conference.
2000 Bianco-Miotto, T., Farmer, B., Sage, E., & Dobrovic, A. (2000). Loss of ABO antigens in myeloid malignancies. Poster session presented at the meeting of Unknown Conference.
2000 Sanders, T., Tan, L. W., Bianco-Miotto, T., & Dobrovic, A. (2000). CPG island microarrays: A tool for detecting methylation changes in cancer. Poster session presented at the meeting of Unknown Conference. South Australia.
2000 Tan, L. W., Bianco-Miotto, T., & Dobrovic, A. (2000). Connexin 26 is methylated in a high proportion of breast cancer patients. Poster session presented at the meeting of Proceedings of the 91st Annual Meeting of the American Association for Cancer Research. USA: AACR.

Software

Year Citation
2016 Mayne, B., Leemaqz, S., Buckberry, S., rodriguez lopez, C., roberts, C., bianco-miotto, T., & Breen, J. (2016). msgbsR: an R package for analysing methylation sensitive genotyping by sequencing data [Electronic]. github.
DOI
  • 2018: $25,000, Robinson Research Institute Innovation Seed Funding Program, Placental cell specific transcriptome and epigenome across gestation. CIs: Bianco-Miotto T, Lister R, Roberts CT.  
  • 2016-2020: $1,333,000, R01 HD089685-01 NIH NICHD, Maternal molecular profiles reflect placental function and development across gestation. CI: Roberts CT, Co-Investigators: Dekker G, Bianco-Miotto T, Smith AK, Breen J.
  • 2016: $25,000, Robinson Research Institute Engaging Opportunities Program, The conception of a preconception resource-#rightmessage #rightaudience #righttime #conceptionhealthmatters. CIs: Brown H, Breen J, Rumbold A, Hodyl N, Fullston T, Schjenken J, Diener K, Sharkey D, Donnelley M, Bianco-Miotto T, Penno M.
  • 2016: Robinson Research Institute Travel Grant to attend the ANZPRA Satellite Meeting (20-21 August, Gold Coast) and the ESA/SRB/ANZBMS Joint meeting 2016 (21-24 August, Gold Coast).
  • 2014-2016: $534,022, NHMRC Project Grant (APP1059120), Fetal sex: an important determinant of the placental transcriptome. CIs: Roberts C, Clifton V, Shoubridge C, Bianco-Miotto T, Bent S.
  • 2015: $22,700, Robinson Research Institute Innovation Seed Funding Program, Determining the relative importance of intrauterine and childhood nutritional exposures on telomere length in children. CIs: Grieger G, Roberts CT, Gatford KL, Bianco-Miotto T.
  • 2015: Robinson Research Institute Travel Grant to attend the International Federation of Placenta Associations (IFPA 2015) meeting in Brisbane, Australia, 8-11th September.
  • 2015: $23,500, Waite Research Institute Research Capacity Development Funding, Obesity and Prostate Cancer Risk. CIs: Bianco-Miotto T, Kind K, Rodriguez Lopez C, Breen J, Roberts C, Buckberry S.
  • 2014: $25,000, Robinson Research Institute Innovation Seed Funding Program, Identifying molecular pathways in the placenta that are implicated in the link between preeclampsia and later life coronary artery disease. CIs: Andraweera P, Brown H, Bianco-Miotto T, Bent S.
  • 2013: $70,000, Waite Research Institute High Impact Publications Project, How nutrients regulate the microbiome-genome interactions in the maturing GI tract of preterm infants. Investigators: Muhlhausler B, Penttila I, Bianco-Miotto T, Bent S, Gibson R, McPhee A, Collins C, Zhou J, Makrides M.
  • 2012: $87,500, Cancer Council of South Australia/SAHMRI Beat Cancer Project Grant (APP1030945), An early obesogenic environment and prostate cancer. CIs: Bianco-Miotto T, Owens JA, Tilley WD, Kind KL.

Jan 2018 - current: Program Coorindator, Bachelor of Applied Biology

July 2015 Dec 2016: Program Coordinator, Bachelor of Food and Nutrition Science

2013- 2017: Course Coordinator and Lecturer: Nutrition III (FOOD SC 3502WT)

2015, 2016, 2017, 2018: Course Coordinator: Principles & Practice of Science for App Biology I (SCIENCE 1101WT)

2016, 2017, 2018: Course Coordinator: Research Skills for Applied Biology II (APP BIOL 2500WT)

2018: Lecturer: Foundations of Applied Biology I (APP BIOL 1510WT)

Current Higher Degree by Research Supervision (University of Adelaide)

Date Role Research Topic Program Degree Type Student Load Student Name
2018 Co-Supervisor Investigation of miRNA Expression in Placenta and Maternal Plasma in Response to Pregnancy Doctor of Philosophy Doctorate Full Time Ms Melanie Denise Smith
2018 Co-Supervisor Analysis of Variable Plantago Mucilage Types Doctor of Philosophy Doctorate Full Time Mr James Morgan Cowley
2018 Co-Supervisor Plantago gene expression and regulation associated with seed shattering Doctor of Philosophy Doctorate Full Time Ms Amanda Grace Philpot
2018 Co-Supervisor A Multi-Omics Approach for Characterizing Human Placental Development Doctor of Philosophy Doctorate Full Time Mr Konstantinos Justinian Bogias
2018 Co-Supervisor Investigating the Physiological, Biochemical and Molecular Bases of Ecological Memory of Drought Stress in Grapevines ('Vitis vinifera') Doctor of Philosophy Doctorate Full Time Melanie Nicole Ford
2017 Co-Supervisor Epigenome and transcriptome profiling of the placenta throughout gestation Doctor of Philosophy Doctorate Full Time Ms Qianhui Wan
2017 Co-Supervisor The Effects of Maternal Stress on the DNA- Methylation of PPARG, PPARGC1A and CEBPA in Offspring Doctor of Philosophy Doctorate Full Time Ms Nahal Habibi
2014 Co-Supervisor The Role of Vitamin D in Pregnancy and Pregnancy Outcomes Doctor of Philosophy Doctorate Part Time Miss Rebecca Louise Wilson

Past Higher Degree by Research Supervision (University of Adelaide)

Date Role Research Topic Program Degree Type Student Load Student Name
2015 - 2018 Co-Supervisor Omic Characterisation of Placental Development and Phenotype Doctor of Philosophy Doctorate Full Time Mr Benjamin Thomas Mayne
2013 - 2015 Co-Supervisor Hypoxia Induced HIF-1/HIF-2 Activity alters Trophoblast Transcriptional Regulation across Gestation Master of Philosophy (Medical Science) Master Full Time Mrs Sultana Mahabbat-e Khoda
2013 - 2015 Co-Supervisor The Effect of Vitamin D on Placental Development and Pregnancy Success Doctor of Philosophy Doctorate Full Time Ms Jessica Phillips
2012 - 2015 Co-Supervisor An Integrative Analysis of the Human Placental Transcriptome Doctor of Philosophy Doctorate Full Time Mr Sam Buckberry
2011 - 2015 Co-Supervisor Omega-3 Fatty Acids in the Early Origins of Metabolic Syndrome Doctor of Philosophy Doctorate Full Time Miss Jing Zhou
2010 - 2016 Co-Supervisor The Role of Estrogen Receptor and the Androgen Receptor in Human Breast Cancer Doctor of Philosophy Doctorate Part Time Mrs Shalini Jindal
2006 - 2010 Principal Supervisor The Role of Epigenetic Modifications in Prostate Tumourigenesis Doctor of Philosophy Doctorate Full Time Ms Karen Huiqin Chiam

Committee Memberships

Date Role Committee Institution Country
2015 - ongoing Chair Epigenetics Consortium of South Australia (EpiCSA) Inc Australia
2014 - ongoing Member Nutrition Society of Australia
2013 - ongoing Member Australian and New Zealand Placental Research Association (ANZPRA)
2012 - 2014 Director Australian Society for Medical Research (ASMR)
2011 - ongoing Member Healthy Development Adelaide (HDA)
2009 - ongoing Member Society for Reproductive Biology (SRB)
2009 - ongoing Member Australian Epigenetic Alliance (AEpiA)
2006 - ongoing Member Endocrine Society of Australia (ESA)
2005 - ongoing Member American Association for Cancer Research (AACR) United States
2005 - ongoing Member Australian Society for Medical Research (ASMR)
Position
Senior Lecturer
Phone
83130775
Campus
Waite
Building
Plant Research Centre, floor 1
Room Number
1 85
Org Unit
School of Agriculture, Food and Wine

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