School of Agriculture, Food and Wine
Faculty of Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
I was appointed a Lecturer at the University of Adelaide in 2013, previous to which I held the W Bruce Hall Cancer Council SA Research Fellowship (2009-2012) and a NHMRC Peter Doherty Fellowship (2005-2009). My undergraduate and postgraduate studies have been undertaken at the University of Adelaide, with my PhD awarded in 2002. I have been a University of Adelaide Staff member since 2003. Since 2017 I have been appointed as a Senior Lecturer.
I am currently the Program Coordinator of the Bachelor of Applied Biology and I coordinate the courses: Foundations of Applied Biology I and Research Skills for Applied Biology II. I am also involved in teaching Nutrition III within the Bachelor of Food and Nutrition Science and Agricultural Genetics II within the Bachelor of Agricultural Sciences.
My area of expertise is in epigenetics and in particular the role of epigenetic mechanisms in healthy development and disease. I work on epigenetics in diverse areas from its role in cancer development, treatment and prognosis to human placental development/pregnancy health. In addition, I am also interested in the role of epigenetic mechanisms in developmental origins of adult health and disease as well as its role in key developmental plant processes. I use numerous models to answer critical questions regarding the mechanistic role of epigenetics which include cell lines, animal models, plant systems and tissue explants. I actively investigate all key areas of epigenetics including DNA methylation, histone modifications, microRNAs and long non-coding RNAs from a single key gene level to the use of arrays or sequencing for global profiling. I am committed to training and exposing others to epigenetics through my role as a lecturer, higher degree research student supervisor and through the Epigenetics Consortium of South Australia (EpiCSA) Inc which I co-founded in 2015 to disseminate and foster an environment where SA epigenetic researchers from all universities/institutes and diverse disciplines have a forum for presenting their work and for networking opportunities. As a Research Leader in Epigenetics within the Robinson Research Institute and a member of the Waite Research Institute, I have collaborations across the areas of human, animal and plant reproduction and development.
- My Research
- Grants and Funding
- Professional Activities
Dr Bianco-Miotto was appointed a lecturer within the School of Agriculture, Food and Wine in March 2013 and is a member of the Robinson Research Institute, University of Adelaide. Previous to this, Dr Bianco-Miotto was the W Bruce Hall Cancer Council SA Research Fellow (2009-2012) and a NHMRC Peter Doherty Fellow (2005-2009). Dr Bianco-Miotto was a Director of the Australian Society for Medical Research (ASMR) (Nov 2012- Nov 2014) and Convenor of the 2014 Australian Health and Medical Research Congress. As of June 2015 she is the Chairperson and Co-founder of the Epigenetics Consortium of South Australia (EpiCSA) Incorporated. Dr Bianco-Miotto has worked extensively with epigenetic mechanisms and methodologies and has contributed to the understanding of the role of DNA methylation in several different cancers. More recently, she has focused on how environmental factors, such as diet, may perturb epigenetic modifications which may result in an increased susceptibility to diseases later in life. Dr Bianco-Miotto has utilised numerous models in her research from rodent models including transgenic models, to human cells, tissue explants and clinical specimens. Dr Bianco-Miotto is currently working on identifying DNA methylation biomarkers for cancer diagnosis, as well as for predicting pregnancy complications. Her expertise in genetics, epigenetics and molecular biology have been applied to research projects ranging from pregnancy to cancer. Her focus is on environmental perturbations and how they contribute to future disease risk.
Date Position Institution name 2017 Senior Lecturer (Level C) University of Adelaide 2013 - 2016 Lecturer (Level B) University of Adelaide 2009 - 2013 Cancer Council SA, W Bruce Hall Cancer Research Fellow (Level B) University of Adelaide 2007 - 2009 NHMRC Peter Doherty Fellow (Level B) University of Adelaide 2005 - 2006 NHMRC Peter Doherty Fellow (Level A) University of Adelaide 2003 - 2004 Postdoctoral Fellow (Level A) University of Adelaide 2002 - 2003 Research Officer Royal Adelaide Hospital
Date Institution name Country Title 1998 - 2002 University of Adelaide Australia PhD 1997 - 1997 University of Adelaide Australia Bachelor of Health Sciences (Hons) 1993 - 1996 University of Adelaide Australia Bachelor of Science
Year Citation 2018 Andraweera, P., Dekker, G., Arstall, M., Bianco-Miotto, T., & Roberts, C. (2018). Complications of pregnancy and future cardiovascular risk. In R. Vasan, & D. Sawyer (Eds.), Encyclopedia of Cardiovascular Research and Medicine (Vol. 1, pp. 643-650). Netherlands: Oxford:Elsevier Inc. 2013 Chiam, K., Day, T., & Bianco-Miotto, T. (2013). Recent updates on epigenetic biomarkers for prostate cancer. In F. H. Sarkar (Ed.), Epigenetics and Cancer (pp. 129-150). Online: Springer Netherlands.
2009 Buchanan, G., Need, E., Bianco-Miotto, T., Greenberg, N., Scher, H., Centenera, M., . . . Tilley, W. (2009). Insights from AR gene mutations. In D. Tindall, & J. Mohler (Eds.), Androgen action in prostate cancer (pp. 207-240). Dordrecht, Netherlands: Springer.
Year Citation 2018 Roberts, C. T., Mayne, B., Leemaqz, S., McAninch, D., Breen, J., Andraweera, P., & Bianco-Miotto, T. (2018). PLACENTAL NON-CODING RNA EXPRESSION CHANGES DYNAMICALLY ACROSS GESTATION. In PLACENTA Vol. 69 (pp. E2). Tokyo, JAPAN: W B SAUNDERS CO LTD. 2018 Grzeskowiak, L. E., Smithers, L. G., Grieger, J. A., Bianco-Miotto, T., Leemaqz, S. Y., Clifton, V. L., . . . Roberts, C. T. (2018). Asthma associated with infertility-but not among women taking regular asthma preventers: Evidence from the international scope study. In PHARMACOEPIDEMIOLOGY AND DRUG SAFETY Vol. 27 (pp. 238-239). WILEY. 2017 Wilson, R. L., Jankovic-Karasoulous, T., McAninch, D., Roberts, C. T., & Bianco-Miotto, T. (2017). IMMUNOLOCALISATION OF 5-METHYLCYTOSINE AND 5HYDROXYMETHYLCYTOSINE IN THE PLACENTA ACROSS GESTATION REVEALS DYNAMIC CO -LOCALISATION OF EXPRESSION. In PLACENTA Vol. 57 (pp. 260-261). Manchester, ENGLAND: W B SAUNDERS CO LTD.
2016 Wilson, R., Leemaqz, S., Goh, Z., McAninch, D., Jankovic-Karasoulos, T., Bianco-Miotto, T., & Roberts, C. (2016). ZINC DEFICIENCY ALTERS PLACENTAL DEVELOPMENT AND MATERNAL HEMODYNAMICS CONTRIBUTING TO FETAL GROWTH RESTRICTION IN MICE. In PLACENTA Vol. 45 (pp. 80). Portland, OR: W B SAUNDERS CO LTD.
2015 Bianco-Miotto, T., Lopez, C. R., Leemaqz, S., Buckberry, S., McCullough, D., Zhuang, Z., . . . Roberts, C. (2015). DNA METHYLATION BIOMARKERS FOR PREDICTING PREGNANCY COMPLICATIONS. In PLACENTA Vol. 36 (pp. A38-A39). W B SAUNDERS CO LTD.
2006 Murphy, N., Bianco-Miotto, T., Ricciardelli, C., Ruiz, A., Segara, D., McNeil, C., . . . Tilley, W. (2006). Expression of the androgen receptor and its association with disease outcome in breast cancer. In Breast Cancer Research and Treatment Vol. 100 (pp. S262-S263). San Antonio, Texas: Springer.
Year Citation 2016 Mayne, B., Leemaqz, S., Buckberry, S., rodriguez lopez, C., roberts, C., bianco-miotto, T., & Breen, J. (2016). msgbsR: an R package for analysing methylation sensitive genotyping by sequencing data [Electronic]. github.
- 2019: Robinson Research Institute Travel Grant to attend and present at the DOHaD 2019 World Congress (20-23 October, Melbourne) & DOHaD ANZ 2019 Symposium: Understanding Mechanisms Guiding Interventions: Developmental Physiology Approaches (24 October, Melbourne).
- 2018: $25,000, Robinson Research Institute Innovation Seed Funding Program, Placental cell specific transcriptome and epigenome across gestation. CIs: Bianco-Miotto T, Lister R, Roberts CT.
- 2016-2020: $1,333,000, R01 HD089685-01 NIH NICHD, Maternal molecular profiles reflect placental function and development across gestation. CI: Roberts CT, Co-Investigators: Dekker G, Bianco-Miotto T, Smith AK, Breen J.
- 2016: $25,000, Robinson Research Institute Engaging Opportunities Program, The conception of a preconception resource-#rightmessage #rightaudience #righttime #conceptionhealthmatters. CIs: Brown H, Breen J, Rumbold A, Hodyl N, Fullston T, Schjenken J, Diener K, Sharkey D, Donnelley M, Bianco-Miotto T, Penno M.
- 2016: Robinson Research Institute Travel Grant to attend the ANZPRA Satellite Meeting (20-21 August, Gold Coast) and the ESA/SRB/ANZBMS Joint meeting 2016 (21-24 August, Gold Coast).
- 2014-2016: $534,022, NHMRC Project Grant (APP1059120), Fetal sex: an important determinant of the placental transcriptome. CIs: Roberts C, Clifton V, Shoubridge C, Bianco-Miotto T, Bent S.
- 2015: $22,700, Robinson Research Institute Innovation Seed Funding Program, Determining the relative importance of intrauterine and childhood nutritional exposures on telomere length in children. CIs: Grieger G, Roberts CT, Gatford KL, Bianco-Miotto T.
- 2015: Robinson Research Institute Travel Grant to attend the International Federation of Placenta Associations (IFPA 2015) meeting in Brisbane, Australia, 8-11th September.
- 2015: $23,500, Waite Research Institute Research Capacity Development Funding, Obesity and Prostate Cancer Risk. CIs: Bianco-Miotto T, Kind K, Rodriguez Lopez C, Breen J, Roberts C, Buckberry S.
- 2014: $25,000, Robinson Research Institute Innovation Seed Funding Program, Identifying molecular pathways in the placenta that are implicated in the link between preeclampsia and later life coronary artery disease. CIs: Andraweera P, Brown H, Bianco-Miotto T, Bent S.
- 2013: $70,000, Waite Research Institute High Impact Publications Project, How nutrients regulate the microbiome-genome interactions in the maturing GI tract of preterm infants. Investigators: Muhlhausler B, Penttila I, Bianco-Miotto T, Bent S, Gibson R, McPhee A, Collins C, Zhou J, Makrides M.
- 2012: $87,500, Cancer Council of South Australia/SAHMRI Beat Cancer Project Grant (APP1030945), An early obesogenic environment and prostate cancer. CIs: Bianco-Miotto T, Owens JA, Tilley WD, Kind KL.
Jan 2018 - current: Program Coordinator, Bachelor of Applied Biology
July 2015 – Dec 2016: Program Coordinator, Bachelor of Food and Nutrition Science
2013- 2017: Course Coordinator and Lecturer: Nutrition III (FOOD SC 3502WT)
2015, 2016, 2017, 2018: Course Coordinator: Principles & Practice of Science for App Biology I (SCIENCE 1101WT)
2016, 2017, 2018, 2019: Course Coordinator: Research Skills for Applied Biology II (APP BIOL 2500WT)
2018: Lecturer: Foundations of Applied Biology I (APP BIOL 1510WT)
2019: Lecturer: Foundations of Applied Biology IA (APP BIOL 1510WT)
2019: Course Coordinator: Foundations of Applied Biology IB (APP BIOL 1520WT)
2019: Lecturer: Agricultural Genetics II (AGRIC 2510WT)
Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2018 Co-Supervisor Analysis of Variable Plantago Mucilage Types Doctor of Philosophy Doctorate Full Time Mr James Morgan Cowley 2018 Co-Supervisor Plantago gene expression and regulation associated with seed shattering Doctor of Philosophy Doctorate Full Time Ms Amanda Grace Philpot 2018 Co-Supervisor Investigating the Natural Variation in Root Morphology, Root Exudation and Abiotic Stress Resistance among Species of the Plantago Genus Doctor of Philosophy Doctorate Full Time Melanie Nicole Ford 2018 Co-Supervisor Global Analysis of Seed Development during Mucilage Production in Plantago Ovata Doctor of Philosophy Doctorate Full Time Mrs Lina Herliana 2017 Co-Supervisor Epigenome and transcriptome profiling of the placenta throughout gestation Doctor of Philosophy Doctorate Full Time Ms Qianhui Wan 2017 Principal Supervisor The effect of micronutrients in oxidative stress, proliferation and apoptosis in placenta Doctor of Philosophy Doctorate Full Time Ms Nahal Habibi
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2018 Co-Supervisor Omic Characterisation of Placental Development and Phenotype Doctor of Philosophy Doctorate Full Time Mr Benjamin Thomas Mayne 2014 - 2018 Co-Supervisor The Influence of Micronutrients on Placental Development and Pregnancy Outcome Doctor of Philosophy Doctorate Part Time Miss Rebecca Louise Wilson 2013 - 2015 Co-Supervisor Hypoxia Induced HIF-1/HIF-2 Activity alters Trophoblast Transcriptional Regulation across Gestation Master of Philosophy (Medical Science) Master Full Time Mrs Sultana Mahabbat-e Khoda 2013 - 2015 Co-Supervisor The Effect of Vitamin D on Placental Development and Pregnancy Success Doctor of Philosophy Doctorate Full Time Ms Jessica Phillips 2012 - 2015 Co-Supervisor An Integrative Analysis of the Human Placental Transcriptome Doctor of Philosophy Doctorate Full Time Mr Sam Buckberry 2011 - 2015 Co-Supervisor Omega-3 Fatty Acids in the Early Origins of Metabolic Syndrome Doctor of Philosophy Doctorate Full Time Miss Jing Zhou 2010 - 2016 Co-Supervisor The Role of Estrogen Receptor and the Androgen Receptor in Human Breast Cancer Doctor of Philosophy Doctorate Part Time Mrs Shalini Jindal 2006 - 2010 Principal Supervisor The Role of Epigenetic Modifications in Prostate Tumourigenesis Doctor of Philosophy Doctorate Full Time Ms Karen Huiqin Chiam
Date Role Committee Institution Country 2015 - ongoing Chair Epigenetics Consortium of South Australia (EpiCSA) Inc — Australia 2014 - ongoing Member Nutrition Society of Australia — — 2013 - ongoing Member Australian and New Zealand Placental Research Association (ANZPRA) — — 2012 - 2014 Director Australian Society for Medical Research (ASMR) — — 2011 - ongoing Member Healthy Development Adelaide (HDA) — — 2009 - ongoing Member Society for Reproductive Biology (SRB) — — 2009 - ongoing Member Australian Epigenetic Alliance (AEpiA) — — 2006 - ongoing Member Endocrine Society of Australia (ESA) — — 2005 - ongoing Member American Association for Cancer Research (AACR) — United States 2005 - ongoing Member Australian Society for Medical Research (ASMR) — —
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