Research Interests
Cancer Therapy Complementary & Alternative Medicine Gastroenterology and Hepatology Immunology Medical and Health Sciences Medical Biochemistry: Lipids Medical Physiology Nutrition and Dietetics Physiology Preventive Medicine Cancer Biology and Clinical Oncology Immunology and Infection Nutrition and Metabolic HealthDr Suzanne Mashtoub
School of Pharmacy and Biomedical Science
College of Health
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Suzanne MashtoubBSc (Biomed), Hons, PhD (Med), Grad Cert Ed (Higher Ed), MDDr Suzanne Mashtoub is a Grant-Funded Researcher leading a research group at the Gastroenterology Department, Women’s and Children’s Hospital. In 2017, Dr Mashtoub completed a NHMRC Postdoctoral Biomedical (Doherty) Fellowship focussing on the efficacy of nutraceuticals (particularly Emu Oil, first used by Indigenous Australian people) in intestinal diseases, including the inflammatory bowel diseases (ulcerative colitis and Crohn's disease), associated colorectal cancer and chemotherapy-induced mucositis. Dr Mashtoub’s team specialises in pre-clinical models of intestinal disorders, as part of the wider Digestive Health Research Group. Extending promising pre-clinical findings, Dr Mashtoub has been funded by the Channel 7 Children’s Research Foundation and the Nutricia Research Foundation to conduct the world’s first clinical trial translating the efficacy of Emu Oil (encapsulated) in children with ulcerative colitis.
Active projects available for Honours/Masters/PhD students:
Project 1
Clinical trial of orally-administered Emu Oil in children with ulcerative colitis
Ulcerative colitis (UC) is a chronic, relapsing, incurable and debilitating inflammatory bowel disease which commonly has its onset during childhood and adolescent years. Despite attaining remission, children are at risk of clinical recurrence, side-effects from corticosteroids, surgery and poor growth, highlighting the need to identify novel therapeutic approaches. Previously, we highlighted the anti-inflammatory and reparative properties of orally-administered Emu Oil, extracted from Emu fat, in several models of intestinal disorders, including UC. It is important to translate these encouraging preclinical findings in the human setting. This project aims to determine whether orally-administered Emu Oil maintains remission in children with UC, in a prospective, placebo-controlled, double-blinded, randomized, early-phase cross over clinical trial.
Location: Gastroenterology Department, Women's and Children's Hospital
Available for Masters/PhD student
| Date | Position | Institution name |
|---|---|---|
| 2023 - ongoing | Adjunct Senior Lecturer | Flinders University |
| 2020 - ongoing | Visiting Senior Research Fellow | University of South Australia |
| 2019 - ongoing | Grant-Funded Researcher | University of Adelaide |
| 2018 - ongoing | Adjunct Senior Research Fellow | University of Western Australia |
| 2017 - ongoing | Adjunct Senior Lecturer | University of Adelaide |
| 2014 - 2017 | National Health & Medical Research Council (NHMRC) Postdoctoral (Peter Doherty) Fellowship | University of Western Australia |
| 2014 - 2017 | Research Assistant Professor | University of Western Australia |
| 2014 - 2017 | Adjunct Lecturer | University of Adelaide |
| 2009 - 2019 | Tutor, Lecturer, Demonstrator, Marker | University of Adelaide |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2023 | Award | Chancellor’s Letter of Commendation 2023 | Flinders University | Australia | - |
| 2022 | Award | Faculty of Health and Medical Sciences Research Travel Award | The University of Adelaide | Australia | - |
| 2018 | Scholarship | Travel Grant | Healthy Development Adelaide | Australia | - |
| 2017 | Award | Poster of Merit Award | Australian Gastroenterology Week | Australia | - |
| 2016 | Award | New Investigator Award | International Society for the Study of Fatty Acids and Lipids | South Africa | - |
| 2016 | Achievement | Young Investigator Award Finalist | Australian Gastroenterology Week | Australia | - |
| 2015 | Award | SA Young Tall Poppy Award | Australian Institute of Policy and Science | Australia | - |
| 2015 | Achievement | SA Tall Poppy of the Year Finalist | Australian Institute of Policy and Science | Australia | - |
| 2015 | Award | Science and Technology Award Winner | Channel 9 Young Achiever Awards | Australia | - |
| 2014 | Scholarship | NHMRC Early Career Postdoctoral (Peter Doherty) Fellowship | NHMRC | Australia | - |
| 2014 | Scholarship | Cancer Council WA Postdoctoral Fellowship | Cancer Council of WA | Australia | - |
| 2013 | Scholarship | Travel Grant | School of Animal and Veterinary Sciences, The University of Adelaide | Australia | - |
| 2013 | Scholarship | The 2013 Trevor Prescott Freemasons Memorial Scholarship | Freemasons Foundation | Australia | - |
| 2013 | Award | Dean’s Commendation for Doctoral Thesis Excellence | The University of Adelaide | Australia | - |
| 2013 | Achievement | The Governor’s Multicultural Award Finalist | Government of SA | Australia | - |
| 2012 | Achievement | SA Young Investigator Award Finalist | Women’s and Children’s Hospital | Australia | - |
| 2011 | Award | Best Oral Presentation | Joint Annual Scientific Meeting of The Nutrition Society of Australia and the Nutrition Society of New Zealand | New Zealand | - |
| 2011 | Award | Leadership Award Winner | Channel 9 Young Achiever Awards | Australia | - |
| 2011 | Scholarship | Travel Grant | Rural Industries Research & Development Corporation | Australia | - |
| 2010 | Scholarship | Travel Award | Nutrition Society of Australia | Australia | - |
| 2010 | Scholarship | The 2010 Trevor Prescott Freemasons Memorial Scholarship | Freemasons Foundation | Australia | - |
| 2010 | Scholarship | Travel Grant | Gastroenterological Society of Australia | Australia | - |
| 2010 | Award | Best Poster Presentation | Australian Gastroenterology Week | Australia | - |
| 2010 | Achievement | 3 Minute Thesis Competition Finalist | The University of Adelaide | Australia | - |
| 2009 | Scholarship | AstraZeneca Junior Travel Award | Gastroenterological Society of Australia | Australia | - |
| 2009 | Scholarship | Australian Postgraduate Award | Australian Postgraduate Award | Australia | - |
| 2009 | Scholarship | PhD Top-up Scholarship | Rural Industries Research & Development Corporation | Australia | - |
| 2008 | Recognition | The Golden Key International Honour Society | The Golden Key International Honour Society | Australia | - |
| 2008 | Scholarship | Gastroenterological Society of Australia Travel Grant | Gastroenterological Society of Australia | Australia | - |
| 2008 | Award | Best Poster & Oral Presentation Award | The University of Adelaide | Australia | - |
| 2008 | Award | Top Honours in Physiology Cohort Award | The University of Adelaide | Australia | - |
| 2008 | Scholarship | Travel Grant | Rural Industries Research & Development Corporation | Australia | - |
| 2008 | Scholarship | The 2008 Basil Hetzel Institute Honours Research Scholarship | Basil Hetzel Institute | Australia | - |
| 2007 | Scholarship | Carpe Diem Travel Award | Rotary Club | Australia | - |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2019 - 2022 | Flinders University | Australia | Doctor of Medicine |
| 2017 - 2017 | Flinders University | Australia | Grad Cert Education (Higher Education) |
| 2009 - 2013 | University of Adelaide | Australia | Doctor of Philosophy (Medicine) |
| 2008 - 2008 | University of Adelaide | Australia | Honours (First Class) |
| 2005 - 2007 | University of Adelaide | Australia | BSc (Biomedical Science) |
| Year | Citation |
|---|---|
| 2024 | Thomson, S., Kennewell, T., Howarth, G., & Mashtoub, S. (2024). Distal colonic crypt hyperplasia is not adversely impacted by emu oil and saireito in a murine model of colitis-associated colorectal cancer. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 39 (pp. 42). WILEY. |
| 2024 | Mhlanga, S. N., Howarth, G. S., Maiolo, K. E., Chartier, L. C., Trinder, D., Lawrance, I. C., . . . Mashtoub, S. (2024). Orally-Administered Emu Oil Reduces Proximal Colonic Crypt Hyperplasia in a Murine Model of Colitis-Associated Colorectal Cancer (vol 8, 102567, 2024). In CURRENT DEVELOPMENTS IN NUTRITION Vol. 8 (pp. 1 page). ELSEVIER SCIENCE INC. |
| 2024 | Mhlanga, S. N., Howarth, G. S., Ndukwe, S., Wanner, K. E., Mitchell, C. J., Chartier, L. C., & Mashtoub, S. (2024). Emu Oil-Modulated Faecal Microbiota Transplantation Improves Disease Indicators in a Mouse Model of Crohn's-Like Colitis (vol 8, 103476, 2024). In CURRENT DEVELOPMENTS IN NUTRITION Vol. 8 (pp. 1 page). ELSEVIER SCIENCE INC. |
| 2022 | Ndukwe, S., Wanner, K., Mitchell, C., Chartier, L., Howarth, G., & Mashtoub, S. (2022). Emu oil-modulated fecal microbiota transplantation reduces histologically assessed disease severity in a mouse model of Crohn's-like colitis. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 37 (pp. 105-106). WILEY. |
| 2018 | Chartier, L. C., Maiolo, K. E., Howarth, G. S., Lawrance, I., Trinder, D., Barker, S. J., . . . Mashtoub, S. (2018). EMU OIL IMPROVES CLINICAL INDICATORS OF DISEASE AND REDUCES PROXIMAL COLONIC CRYPT HYPERPLASIA IN A MURINE MODEL OF COLITIS-ASSOCIATED COLORECTAL CANCER. In GASTROENTEROLOGY Vol. 154 (pp. S875). Washington, DC: W B SAUNDERS CO-ELSEVIER INC. WoS2 |
| 2014 | Cheah, K. Y., Howarth, G. S., Bindon, K. A., Kennedy, J. A., Mashtoub, S., & Bastian, S. E. (2014). Low Molecular Weight Procyanidins From Grape Seeds Enhance the Impact of 5-Fluorouracil Chemotherapy on Colon Cancer Cells. In GASTROENTEROLOGY Vol. 146 (pp. S341). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC. WoS1 |
| 2009 | Mashtoub, S., Lindsay, R., Lymn, K., Geier, M., Butler, R., & Howarth, G. (2009). Emu oil improves parameters of intestinal integrity in rat models of inflammatory bowel disease and intestinal mucositis. In Abstracts of the 2009 International MASCC/ISOO Symposium (pp. 910-911). Italy: Springer. DOI |
| Year | Citation |
|---|---|
| 2023 | Wanner, K. E., Mitchell, C. J., Mhlanga, S. N., Howarth, G. S., Chartier, L. C., & Mashtoub, S. (2023). Emu Oil-modulated faecal microbiota transplantation restores distal colonic barrier function in a mouse model of Crohn’s-like colitis. DOI |
| 2023 | Mashtoub, S., & Howarth, G. (2023). Emu Oil and Zinc Monoglycerolate Influence the Course of Disease in a Rat Model of Ulcerative Colitis. DOI |
Project grants (last 5 years only)
- Nutricia Research Foundation Grant (2020); 30,000 euro [approx $50,000] (Chief Investigator)
Project entitled: Clinical trial of orally-administered Emu Oil in children with ulcerative colitis - Collaboration Grant, The University of Adelaide (2019); $3,500 (Co-Investigator)
Project entitled: Influence of Emu Oil on gut microbiome in Crohn’s disease following faecal transplant - Research Themes Investment Scheme 2018 Seed Funding, University of South Australia; $40,000 (Partner Investigator 1)
Project entitled: Developing novel therapeutics for the treatment of inflammatory gastrointestinal conditions including colon cancer - Channel 7 Children’s Research Foundation (2018); $75,000 (Chief Investigator)
Project entitled: Clinical trial of orally-administered Emu Oil to protect against ulcerative colitis in children - Collaboration Grant, The University of Adelaide (2018); $4000 (Chief Investigator)
Project entitled: Immunomodulatory effects of Emu Oil in a mouse model of colitis-associated colorectal cancer. - Australian Veterinary Association Animal Welfare Grant (2018); $10,000 (Co-Principal investigator)
Project entitled: Pain as assessed by facial grimace in the mouse (strain- C57BL/6)
Industry grants (last 5 years only)
- Oncology Research International Limited (ORIL; 2016); $150,000 (Co-Principal Investigator)
Project entitled: Assessment of ORIL formulation in a mouse model of inflammation-associated colorectal cancer - Story Pharmaceutics Pty Ltd (2015); $37,714 (Co-Principal Investigator)
Project entitled: Emu Oil in combination with a test compound in a rat model of ulcerative colitis
Dr Mashtoub's dedication to education extends beyond her supervision of PhD, Honours, DVM, undergraduate and MD Advanced Studies students. Since 2009, Dr Mashtoub has adopted several teaching roles within the Adelaide Medical School (AMS) for MBBS Case Based Learning, Human Biology I, Principles of Human Health & Disease I, Physiology II and Investigative Cell Biology III and the School of Animal and Veterinary Sciences (SAVS) for Animal Form & Function III. Additionally, Dr Mashtoub provides guest lectures for Fundamentals in Human Nutrition (AMS) and Statistics (SAVS).
Dr Mashtoub's passion for teaching was further defined during her Graduate Certificate in Education (Higher Education), completed at Flinders University in 2017. Dr Mashtoub explored various traditional and contemporary undergraduate pedagogical strategies that aim to encourage and foster self-regulated learning; concepts Dr Mashtoub extend towards her students in all teaching environments.
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2024 | Principal Supervisor | Clinical trial of orally-administered Emu Oil in children with ulcerative colitis. | Doctor of Philosophy | Doctorate | Full Time | Ms Sisanda Nomcebo Mhlanga |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2017 - 2021 | Co-Supervisor | Emu Oil in Combination with Herbal Preparations Provides a Novel Adjunctive Approach to Colitis-Associated Colorectal Cancer Prevention | Doctor of Philosophy | Doctorate | Full Time | Miss Lauren Claire Chartier |
| Date | Role | Research Topic | Location | Program | Supervision Type | Student Load | Student Name |
|---|---|---|---|---|---|---|---|
| 2019 - ongoing | Co-Supervisor | Novel approaches for treatment of infected wounds | UniSA | - | Doctorate | Full Time | Miss Tahlia Kennewell |
| Date | Role | Board name | Institution name | Country |
|---|---|---|---|---|
| 2018 - ongoing | Director | STEM Centre Australia | STEM Centre Australia | Australia |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2023 - ongoing | Member | SALHN Medical Education & Training Committee | SALHN | Australia |
| 2023 - ongoing | Member | SALHN Junior Medical Advisory Committee | SALHN | Australia |
| 2023 - ongoing | Member | SALHN Aboriginal & Torres Strait Islander Cultural Events Working Group | SALHN | Australia |
| 2019 - ongoing | Member | MBBS Admissions Committee | The University of Adelaide | Australia |
| 2019 - ongoing | Member | Organising Committee (New Investigator subgroup) | World Congress on Paediatric Neurogastroenterology and Motility | Australia |
| 2019 - ongoing | Member | NHMRC Ideas Grant Peer Review Panel | NHMRC | Australia |
| 2018 - 2018 | Member | MD Year 4 (Research Enquiry Project) Development Working Group | The University of Adelaide | Australia |
| 2017 - ongoing | Member | Animal Ethics (Medical) Committee (Category B Committee Member) | The University of Adelaide | Australia |
| 2017 - ongoing | Member | Animal Ethics Committee (Category B Committee Member) | Women's and Children's Hospital | Australia |
| 2015 - 2020 | Member | Nutrition Society of Australia (SA Branch) | Nutrition Society of Australia | Australia |
| 2012 - 2013 | Member | Australian Society for Medical Research (SA Branch) | Australian Society for Medical Research | Australia |
| 2010 - 2013 | Member | Consumer Reference Group | General Practice Network South | Australia |
| Date | Title | Engagement Type | Institution | Country |
|---|---|---|---|---|
| 2019 - ongoing | Health & Human Rights Group | Public Community Engagement | Flinders University | Australia |
| 2018 - 2020 | 'Talking with Aussies' program | Public Community Engagement | The University of Adelaide | Australia |
| 2008 - 2013 | Healthy Development Adelaide Education Program | Public Community Engagement | Healthy Development Adelaide | Australia |