Sisanda Mhlanga

Miss Sisanda Mhlanga

Higher Degree by Research Candidate

School of Pharmacy and Biomedical Sciences

College of Health


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Sisanda Mhlanga is a PhD Candidate in Medicine at the University of Adelaide and the Women’s and Children’s Hospital, Australia. Her research focuses on ulcerative colitis, a chronic inflammatory bowel disease, with a particular interest in evaluating the therapeutic potential of natural bioactive compounds. She is leading a world-first clinical trial investigating Emu Oil as a potential adjunct therapy for paediatric ulcerative colitis and conducts translational research examining the complex interactions between intestinal inflammation, mucosal repair, the gut microbiome, and microbial metabolites. Her work aims to advance the development of novel, evidence-based therapies that improve clinical outcomes and quality of life for individuals living with inflammatory bowel disease.

Date Institution name Country Title
2023 - 2026 University of Adelaide Australia Doctor of Philosophy
2022 - 2022 Flinders University Australia Graduate Certificate in Public Health
2019 - 2021 University of Adelaide Australia Bachelor of Health and Medical Science

Year Citation
2026 Mhlanga, S. N., Howarth, G. S., & Mashtoub, S. (2026). Emu Oil: A Potential Adjunct to Inflammatory Bowel Disease Treatment?. Inflammatory Intestinal Diseases, 11(1), 53-64.
DOI
2026 Mashtoub, S., Mhlanga, S. N., Cheah, K. Y., & Howarth, G. S. (2026). Differing Emu Oil sources yield similar outcomes whilst Ostrich Oil demonstrates minimal effect in a rat model of chemotherapy-induced mucositis. Clinical Nutrition Espen, 74, 9 pages.
DOI
2025 Price, Z. K., Lokman, N. A., Morrison, J., Mhlanga, S. N., Sugiyama, M., Koya, Y., . . . Ricciardelli, C. (2025). Identification of Sphingosine Kinase 1 as a Novel Protein Regulated by High Molecular Weight Hyaluronan in Ovarian Cancer.. J Cell Mol Med, 29(9), e70574.
DOI

Year Citation
2025 Mhlanga, S. N., Kaur, H., Howarth, G. S., & Mashtoub, S. (2025). Preclinical translation of animal-derived oils from models of ulcerative colitis to human clinical studies. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 40 (pp. 70-71). WILEY.
2024 Mashtoub, S., Mhlanga, S., Barreto, S. G., Hammond, P., & Howarth, G. (2024). Use of high-resolution colonoscopy to accurately monitor disease progression in a murine model of colitis-associated colorectal cancer. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 39 (pp. 43). WILEY.
2024 Mhlanga, S. N., Howarth, G. S., Maiolo, K. E., Chartier, L. C., Trinder, D., Lawrance, I. C., . . . Mashtoub, S. (2024). Orally-Administered Emu Oil Reduces Proximal Colonic Crypt Hyperplasia in a Murine Model of Colitis-Associated Colorectal Cancer (vol 8, 102567, 2024). In CURRENT DEVELOPMENTS IN NUTRITION Vol. 8 (pp. 1 page). ELSEVIER SCIENCE INC.
2024 Mhlanga, S. N., Howarth, G. S., Ndukwe, S., Wanner, K. E., Mitchell, C. J., Chartier, L. C., & Mashtoub, S. (2024). Emu Oil-Modulated Faecal Microbiota Transplantation Improves Disease Indicators in a Mouse Model of Crohn's-Like Colitis (vol 8, 103476, 2024). In CURRENT DEVELOPMENTS IN NUTRITION Vol. 8 (pp. 1 page). ELSEVIER SCIENCE INC.
DOI
2023 Luminal Basic Science (2023). In Journal of Gastroenterology and Hepatology Vol. 38 (pp. 200-201). Wiley.
DOI

2024     Walter and Dorothy Duncan Trust Grant

2024     Adelaide Graduate Research School Travel Grant Scholarship

2024     University of Adelaide Research Scholarship 

2023     Geoffrey Davidson Gastroenterology Research Development Fellowship Grant

2026 Demonstrator:  MEDI 1001 - Foundation of Medicine 

2025 Demonstrator: ANAT SC 3003 - Applied Human Anatomy

2025 Demonstrator:  MEDIC ST 1502 - Medical Studies 1

2021 Peer Assisted Study Session (PASS) Leader:  ANAT SC 2009 - Musculoskeletal Anatomy & ANAT SC 2006 - Foundations of Human Neuroanatomy 

 

 

 

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2026 - ongoing Co-Supervisor Nutraceutical suppositories for the management of proctitis Flinders University Doctor of Medicine Master Part Time Gamze Bakan
2026 - ongoing Co-Supervisor The impact of nutraceutical interventions on postoperative wound healing: a systematic review and meta-analysis Flinders University Doctor of Medicine Master Part Time Zoe Pasvanis
2026 - ongoing Co-Supervisor Nutraceuticals as adjunctive therapies for ulcerative colitis: effects on clinical indicators compared with standard pharmacological treatment Flinders University Doctor of Medicine Master Part Time Tsz Yan Charis Chan
2026 - ongoing Co-Supervisor The effect of herbal and plant-based nutraceuticals on postoperative recovery in adults undergoing gastrointestinal surgery: a systematic review Flinders University Doctor of Medicine Master Part Time Tanvi Arora
2024 - 2025 Co-Supervisor Double-blinded clinical trial of orally administered Emu Oil in paediatric ulcerative colitis: preliminary analysis of disease activity and intestinal inflammation Women's and Children's Hopital, and Flinders University Doctor of Medicine Master Part Time Lauren Engstrom
2024 - 2025 Co-Supervisor Clinical Trial of Orally Administered Emu Oil for Pediatric Ulcerative Colitis: An Initial Analysis of Participants. Women's and Children's Hospital, and Flinder's University Doctor of Medicine Master Part Time Atnu Bhattacharyya

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