Professor Simon Pyke

• Appointments

  Date	Position	Institution name
  2024 - ongoing	Emeritus Professor	University of Adelaide
  2019 - 2022	Deputy Dean (International), Faculty of Sciences	University of Adelaide
  2015 - 2018	Deputy Dean (Learning & Teaching)	University of Adelaide
  2014 - 2024	Professor	University of Adelaide
  2011 - 2012	Acting Director, Centre for Learning & Professional Development	University of Adelaide
  2009 - 2013	Associate Professor	University of Adelaide
  2007 - 2014	Associate Dean (Learning & Quality)	University of Adelaide
  1998 - 2008	Senior Lecturer	University of Adelaide
  1992 - 1997	Lecturer	University of Adelaide

• Awards and Achievements

  Date	Type	Title	Institution Name	Country	Amount
  2016	Fellowship	Fellow, Royal Society of Chemistry	Royal Society of Chemistry	United Kingdom	-
  2014	Fellowship	Fellow, Royal Australian Chemical Institute	Royal Australian Chemical Institute	Australia	-
  2014	Teaching Award	Fensham Medal for Outstanding Contributions to Chemical Education	Royal Australian Chemical Institute	Australia	-
  2010	Teaching Award	Stephen Cole the Elder Award for Excellence in Teaching	University of Adelaide	Australia	-
  2008	Teaching Award	Citation for Outstanding Contribution to Student Learning	Australian Learning & Teaching Council	Australia	-
  2007	Teaching Award	D. R. Stranks Medal for Excellence in Chemistry Education	Royal Australian Chemical Institute (S.A. Branch)	Australia	-
  2001	Teaching Award	Stephen Cole the Elder Award for Excellence in Teaching	University of Adelaide	Australia	-

• Education

  Date	Institution name	Country	Title
  1985 - 1988	University of Sydney, Sydney	Australia	PhD
  1980 - 1984	University of Sydney, Sydney	Australia	Bachelor of Science (Honours)

• Postgraduate Training

  Date	Title	Institution	Country
  1989 - 1992	Postdoctoral Fellow	University of East Anglia, Norwich	United Kingdom

• Certifications

  Date	Title	Institution name	Country
  —	Chartered Chemist	Royal Australian Chemical Institute	-
  —	Chartered Chemist	Royal Society of Chemistry	-

• Journals

  Year	Citation
  2023	Schultz, M., Southam, D. C., Buntine, M., Colthorpe, K., Howitt, S., Johnson, E., . . . Yucel, R. (2023). 'Transformative': The threshold learning outcomes for science. Australian Journal of Chemistry, 76(12), 908-920. DOI Scopus2 WoS1
  2020	Buntine, M. A., Silva, K. B. D., Kable, S. H., Lim, K. F., Pyke, S. M., Read, J. R., . . . Yeung, A. (2020). Perceptions and Misconceptions about the Undergraduate Laboratory from Chemistry, Physics and Biology Academics. International Journal of Innovation in Science and Mathematics Education, 28(4), 1-15. DOI Scopus1
  2019	Sarkar, M. R., Dasgupta, S., Pyke, S. M., & Bell, S. G. (2019). Selective biocatalytic hydroxylation of unactivated methylene C-H bonds in cyclic alkyl substrates. Chemical Communications, 55(34), 5029-5032. DOI Scopus12 WoS10 Europe PMC4
  2017	Sharma, M., Rifkin, W., Tzioumis, V., Hill, M., Johnson, E., Varsavsky, C., . . . Pyke, S. (2017). Implementing and investigating distributed leadership in a national university network - SaMnet. Journal of Higher Education Policy and Management, 39(2), 169-182. DOI Scopus6 WoS5
  2015	Barrie, S., Bucat, R., Buntine, M., Burke da Silva, K., Crisp, G., George, A., . . . Yeung, A. (2015). Development, evaluation and use of a Student Experience Survey in undergraduate science laboratories: the Advancing Science by Enhancing Learning in the Laboratory Student Laboratory Learning Experience Survey. International Journal of Science Education, 37(11), 1795-1814. DOI Scopus26 WoS22
  2014	Priest, S., Pyke, S., & Williamson, N. (2014). Student perceptions of chemistry experiments with different technological interfaces: a comparative study. Journal of Chemical Education, 91(11), 1787-1795. DOI Scopus7 WoS5
  2013	Williamson, N., Metha, G., Willison, J., & Pyke, S. (2013). Development of POGIL-Style classroom activities for an introductory chemistry course. International Journal of Innovation in Science and Mathematics Education, 21(5), 27-41. Scopus5
  2011	Yeung, A., Pyke, S., Sharma, M., Barrie, S., Buntine, M., Burke Da Silva, K., . . . Lim, K. (2011). The Advancing Science by Enhancing Learning in the Laboratory (ASELL) Project: The first Australian multidisciplinary workshop. International Journal of Innovation in Science and Mathematics Education, 19(2), 51-72. Scopus18
  2011	Simpson, B., Claudie, D., Gerber, J., Pyke, S., Wang, J., McKinnon, R., & Semple, S. (2011). In vivo activity of benzoyl ester clerodane diterpenoid derivatives from Dodonaea polyandra. Journal of Natural Products, 74(4), 650-657. DOI Scopus27 WoS25 Europe PMC7
  2010	Bedgood, D. R., Gardiner, M., Yates, B., Bridgeman, A. J., Morris, G., Buntine, M., . . . Zadnik, M. (2010). THE DEVELOPMENT OF TEACHING SKILLS TO SUPPORT ACTIVE LEARNING IN UNIVERSITY SCIENCE (ALIUS). JOURNAL OF LEARNING DESIGN, 3(3), 10-19. DOI WoS4
  2009	Basu Baul, T., Das, P., Chandra, A., Mitra, S., & Pyke, S. (2009). The synthesis, characterization and structures of some 4-[((E)-1-{2-hydroxy-5-[(E)-2-(aryl)-1-diazenyl]phenyl}methylidene)amino]benzoic acid. Dyes and Pigments, 82(3), 379-386. DOI Scopus24 WoS24
  2008	Smith, J., Jones, R., Booker, G., & Pyke, S. (2008). Sequential and Selective Buchwald-Hartwig Amination Reactions for the Controlled Functionalization of 6-Bromo-2-chloroquinoline: Synthesis of Ligands for the Tec Src Homology 3 Domain. Journal of Organic Chemistry, 73(22), 8880-8892. DOI Scopus35 WoS33 Europe PMC10
  2008	Kerr, P., Pyke, S., & Ward, A. (2008). Synthesis and cyclization to aurones and flavones of alkoxy-substituted aryl arylalkynyl ketones. Australian Journal of Chemistry, 61(5), 350-358. DOI Scopus8 WoS8
  2008	Burcham, P., Kaminskas, L., Tan, D., & Pyke, S. (2008). Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury. Mini - Reviews in Medicinal Chemistry, 8(4), 319-330. DOI Scopus29 WoS29 Europe PMC21
  2007	Ndi, C., Semple, S., Griesser, H., Pyke, S., & Barton, M. (2007). Antimicrobial compounds from Eremophila serrulata. Phytochemistry, 68(21), 2684-2690. DOI Scopus53 WoS48 Europe PMC18
  2007	Ndi, C., Semple, S., Griesser, H., Pyke, S., & Barton, M. (2007). Antimicrobial compounds from the Australian desert plant Eremophila neglecta. Journal of Natural Products, 70(9), 1439-1443. DOI Scopus52 WoS44 Europe PMC20
  2007	Kaminskas, L., Pyke, S., & Burcham, P. (2007). Michael addition of acrolein to lysinyl and N-terminal residues of a model peptide: targets for cytoprotective hydrazino drugs. Rapid Communications in Mass Spectrometry, 21(7), 1155-1164. DOI Scopus15 WoS14 Europe PMC7
  2006	Inglis, S., Jones, R., Booker, G., & Pyke, S. (2006). Synthesis of N-benzylated-2-aminoquinolines as ligands for the Tec SH3 domain. Bioorganic & Medicinal Chemistry Letters, 16(2), 387-390. DOI Scopus30 WoS29 Europe PMC3
  2006	Burcham, P., & Pyke, S. (2006). Hydralazine inhibits rapid acrolein-induced protein oligomerization: Role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection. Molecular Pharmacology, 69(3), 1056-1065. DOI Scopus75 WoS69 Europe PMC45
  2006	Davies, B., Herbert, M., Culbert, J., Pyke, S., Coller, J., Somogyi, A., . . . Sallustio, B. (2006). Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatography. Journal of Chromatography. B, Analytical Techniques in the Biomedical and Life Sciences, 832(1), 114-120. DOI Scopus17 WoS15 Europe PMC9
  2005	Kaminskas, L., Pyke, S., & Burcham, P. (2005). Differences in lysine adduction by acrolein and methyl vinyl ketone: Implications for cytotoxicity in cultured hepatocytes. Chemical Research in Toxicology, 18(11), 1627-1633. DOI Scopus28 WoS27 Europe PMC14
  2005	Clements, P., Gream, G., Kirkbride, P., & Pyke, S. (2005). Cycloaddition reactions of 7-benzylidenecycloocta-1,3,5-triene with ethenetetracarbonitrile and 4-phenyl-3H-1,2,4-triazole-3,5(4H)-dione. Helvetica Chimica Acta, 88(7), 2003-2021. DOI Scopus5 WoS4
  2005	Inglis, S., Jones, R., Fritz, D., Stojkoski, C., Booker, G., & Pyke, S. (2005). Synthesis of 5-, 6- and 7-substituted-2-aminoquinolines as SH3 domain ligands. Organic & Biomolecular Chemistry, 3(14), 2543-2557. DOI Scopus30 WoS27 Europe PMC12
  2004	Inglis, S., Stojkoski, C., Branson, K., Cawthray, J., Fritz, D., Wiadrowski, E., . . . Booker, G. (2004). Identification and specificity studies of small-molecule ligands for SH3 protein domains. Journal of Medicinal Chemistry, 47(22), 5405-5417. DOI Scopus73 WoS67 Europe PMC26
  2004	Kaminskas, L., Pyke, S., & Burcham, P. (2004). Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde. Organic & Biomolecular Chemistry, 2(18), 2578-2584. DOI Scopus47 WoS44 Europe PMC28
  2004	Kaminskas, L., Pyke, S., & Burcham, P. (2004). Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice. Journal of Pharmacology and Experimental Therapeutics, 310(3), 1003-1010. DOI Scopus68 WoS64 Europe PMC41
  2004	Burcham, P., Fontaine, F., Kaminskas, L., Petersen, D., & Pyke, S. (2004). Protein adduct-trapping by hydrazinophthalazine drugs: Mechanisms of cytoprotection against acrolein-mediated toxicity. Molecular Pharmacology, 65(3), 655-664. DOI Scopus56 WoS52 Europe PMC32
  2003	Burcham, P., Fontaine, F., Petersen, D., & Pyke, S. (2003). Reactivity with tris(hydroxymethyl)aminomethane confounds immunodetection of acrolein-adducted proteins. Chemical Research in Toxicology, 16(10), 1196-1201. DOI Scopus14 WoS14 Europe PMC7
  2003	Creaser, S., Pyke, S., & Lincoln, S. (2003). Complexation of zinc(II) and cadmium(II) by hydroxyethyl- and bis(hydroxyethyl)-1,4,7-triazacyclononane in water. Australian Journal of Chemistry, 56(1), 61-64. DOI Scopus2 WoS1
  2002	Johnstone, K., Pearce, W., & Pyke, S. (2002). Porphyrin building blocks: using a modified Barton-Zard approach to construct annulated pyrroles. Journal of Porphyrins and Phthalocyanines, 6(11-12), 661-672. DOI Scopus6 WoS7
  2002	Burcham, P., Kaminskas, L., Fontaine, F., Petersen, D., & Pyke, S. (2002). Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products. Toxicology, 182-182, 229-236. DOI Scopus93 WoS92 Europe PMC46
  2002	Crossley, M., King, L., Pyke, S., & Tansey, C. (2002). Reaction of 5-nitro-octaethylporphyrins with nucleophiles. Journal of Porphyrins and Phthalocyanines, 6(11-12), 685-694. DOI WoS26
  2001	Kerr, P., Pyke, S., Ward, A., & Tiekink, E. (2001). Crystal structure of (Z)-3-(1,3-benzodioxol-5-yl)-3-chloro-1-[2,4-di(benzyl-oxy)-6-hydroxyphenyl]-2-propen-1-one, C₃₀H₂₃ClO₆. Zeitschrift fur Kristallographie-New Crystal Structures, 216(4), 558-560. Scopus3 WoS3
  2001	Kerr, P., Pyke, S., Ward, A., & Tiekink, E. (2001). Crystal structure of 1-[2,4-di(benzyloxy)-6-hydroxyphenyl]-3-phenyl-2-propyn-1-one, C₂₉H₂₂O₄. Zeitschrift fur Kristallographie-New Crystal Structures, 216(1-4), 565-566. DOI Scopus2 WoS2
  2001	Kerr, P., Pyke, S., Ward, A., & Tiekink, E. (2001). Crystal structure of (E)-1,3-di(2,4,6-trimethoxyphenyl)-2-propen-1-one,C₂₁H₂₄O₇. Zeitschrift fur Kristallographie-New Crystal Structures, 216(4), 567-568. Scopus1 WoS1
  2001	Creaser, S., Pyke, S., & Tiekink, E. (2001). Crystal structure of N1-(1-oxohexahydro-1λ⁶-thiopyran-1-yliden)-1-benzenesulfonamide, C₁₂H₁₇NO₃S₂. Zeitschrift fur Kristallographie-New Crystal Structures, 216(3), 447-448. Scopus2 WoS1
  2001	Creaser, S., Pyke, S., & Tiekink, E. (2001). Crystal structure of N1-(hexahydro-1λ⁶-thiopyran-1-yliden)-1-benzenesulfonamide, C₁₂H₁₇NO₂S₂. Zeitschrift fur Kristallographie-New Crystal Structures, 216(3), 445-446. Scopus2 WoS1
  2001	Pearce, W., Pyke, S., & Tiekink, E. (2001). Crystal structure of 1-(4-nitrophenyl)-3-(phenylsulfonyl)-2,5-dihydro-1H-pyrrole, C₁₆H₁₄N₂O₄S. Zeitschrift fur Kristallographie-New Crystal Structures, 216(1-4), 529-530. DOI Scopus1 WoS1
  2001	Creaser, S., Pyke, S., & Tiekink, E. (2001). Crystal structure of N1-(4,4-dimethoxyhexahydro-1 λ⁶-thiopyran-1-yliden)-4-methyl-1-benzenesulfonamide, C₁₄H₂₁1NO₄S₂. Zeitschrift fur Kristallographie-New Crystal Structures, 216(3), 449-450. DOI Scopus3
  2001	Creaser, S., Pyke, S., & Tiekink, E. (2001). Crystal structure of N1-(3,3-dimethyl-9-oxo-1,5-dioxa-9λ⁶-thiaspiro[5.5]undec-9-yliden)-1-benzenesulfonamide,C₁₇H₂₅NO₄S₂. Zeitschrift fur Kristallographie-New Crystal Structures, 216(3), 451-453.
  2001	Rozek, T., Bowie, J., Pyke, S., Skelton, B., & White, A. (2001). A regio- and stereo-selective synthesis of 2-hydroxy-3-methylochromycinone in three steps from 2-bromo-5-acetoxy-1,4-naphthoquinone and 1-acetoxy-3,3-dimethyl-5-vinylcyclohexa-1,5-diene. Organic & Biomolecular Chemistry, 1(15), 1826-1830. DOI Scopus19 WoS17
  2001	Basu Baul, T., Dhar, S., Pyke, S., Tiekink, E., Rivarola, E., Butcher, R., & Smith, F. (2001). Synthesis and characterization of triorganotin(IV) complexes of 5-[(E)-2-(aryl)-1-diazenyl]-2-hydroxybenzoic acids.: Crystal and molecular structures of a series of triphenyltin 5-[(E)-2-(aryl)-1-diazenyl]-2-hydroxybenzoates (aryl=phenyl, 2-methylphenyl, 3-methylphenyl and 4-methoxyphenyl). Journal of Organometallic Chemistry, 633(01-Feb), 7-17. DOI Scopus83
  2001	Avery, T., Fallon, G., Greatrex, B., Pyke, S., Taylor, D., & Tiekink, E. (2001). Mechanistic investigations on the reaction between 1,2-dioxines and bulky stabilized phosphorus ylides: An efficient route to closely related cyclopropane stereoisomers. Journal of Organic Chemistry, 66(24), 7955-7966. DOI Scopus42 WoS43 Europe PMC7
  2001	Bruce, M., Pyke, S., Zaitseva, N., Skelton, B., & White, A. (2001). Reactions of ethyne with some ruthenium cluster complexes containing dppm. Helvetica Chimica Acta, 84(10), 3197-3215. DOI Scopus12 WoS8
  2001	Semple, S., Pyke, S., Reynolds, G., & Flower, R. (2001). In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus. Antiviral Research, 49(3), 169-178. DOI Scopus139 WoS108 Europe PMC59
  2001	Creaser, S., Pyke, S., & Tiekink, E. (2001). N-(4,4-Dimethoxy-1-oxo-1λ⁶-thianylidene)-4-methyl-1-benzenesulfonamide. Acta Crystallographica Section E-Structure Reports Online, 57(Part 5), O394-O395. DOI
  2001	Kerr, P. J., Pyke, S. M., Ward, A. D., & Tiekink, E. R. T. (2001). Crystal structure of (E)-1,3-di(2,4,6-trimethoxyphenyl)-2-propen-1-one, C<inf>21</inf>H<inf>24</inf>O<inf>7</inf>. Zeitschrift fur Kristallographie - New Crystal Structures, 216(1-4), 601-602. DOI
  2001	Creaser, S. P., Pyke, S. M., & Tiekink, E. R. T. (2001). Crystal structure of N1-(3,3-dimethyl-9-oxo-l,5-dioxa-9λ<sup>6</sup>-thiaspiro[5.5]-undec-9-yliden)-1-benzenesulfonamide, C<inf>17</inf>H<inf>25</inf>NO<inf>4</inf>S<inf>2</inf>. Zeitschrift fur Kristallographie - New Crystal Structures, 216(1-4), 473-475. DOI
  2001	Creaser, S. P., Pyke, S. M., & Tiekink, E. R. T. (2001). Crystal structure of N1-(hexahydro-1λ<sup>6</sup>-thiopyran-1-yliden)-1-benzenesulfonamide, C<inf>12</inf>H<inf>17</inf>NO<inf>2</inf>S<inf>2</inf>. Zeitschrift fur Kristallographie - New Crystal Structures, 216(1-4), 467-468. DOI
  2001	Creaser, S. P., Pyke, S. M., & Tiekink, E. R. T. (2001). Crystal structure of N1-(1-oxohexahydro-1λ<sup>6</sup>-thiopyran-1-yliden)-1-benzenesulfonamide, C<inf>12</inf>H<inf>17</inf>NO<inf>3</inf>S<inf>2</inf>. Zeitschrift fur Kristallographie - New Crystal Structures, 216(1-4), 469-470. DOI
  2001	Kerr, P., Pyke, S., Ward, A., & Tiekink, E. (2001). Crystal structure of (Z)-3-(1,3-benzodioxol-5-yl)-3-chloro-1-[2,4-di(benzyloxy)-6-hydroxyphenyl]-2-propen-1-one, C<inf>30</inf>H<inf>23</inf>ClO<inf>6</inf>. Zeitschrift fur Kristallographie - New Crystal Structures, 216(1-4), 592-594. DOI
  2001	Baul, T. S. B., Dhar, S., Pyke, S. M., Tiekink, E. R. T., Rivarola, E., Butcher, R., & Smith, F. E. (2001). Synthesis and characterization of triorganotin(IV) complexes of 5-[(<i>E</i>)-2-(aryl)-1-diazenyl]-2-hydroxybenzoic acids.: Crystal and molecular structures of a series of triphenyltin 5-[(<i>E</i>)-2-(aryl)-1-diazenyl]-2-hydroxybenzoates (aryl = phenyl, 2-methylphenyl, 3-methylphenyl and 4-methoxyphenyl). JOURNAL OF ORGANOMETALLIC CHEMISTRY, 633(1-2), 7-17. WoS76
  2000	Crisp, M., Pyke, S., & Rendina, L. (2000). Dinuclear organoplatinum (II)-methyldiphenylphosphine complexes of nicotinic acid. Journal of Organometallic Chemistry, 607(1-2), 222-226. DOI Scopus12 WoS11
  1999	Basu Baul, T., Dahr, S., Kharbani, N., Pyke, S., Butcher, R., & Smith, F. (1999). Synthesis and structural characterization of some triorganotin(IV) complexes of 5-(4-chlorophenulazo)salicylic acid: Crystal and molecular structure of triphenyltin 5-(4-chlorophenylazo)salicylate 0.5C₆H₁₄. Main Group Metal Chemistry, 22(7), 413-421. DOI Scopus29 WoS28
  1999	De Vos, D., Clements, P., Pyke, S. M., Smyth, D. R., & Tiekink, E. R. T. (1999). Characterisation and in vitro cytotoxicity of triorganophosphinegold(I) 2-mercaptobenzoate complexes. Metal-Based Drugs, 6(1), 31-40. DOI Scopus41 Europe PMC8
  1999	Creaser, S., Lincoln, S., & Pyke, S. (1999). A general method for the preparation of single pendant arm 2-hydroxyalkyl-1,4,7-triazacyclononane macrocycles. Journal of the Chemical Society, Perkin transactions I, 1(9), 1211-1213. DOI Scopus14 WoS9
  1999	Semple, S., Nobbs, S., Pyke, S., Reynolds, G., & Flower, R. (1999). Antiviral flavanoid from Pterocaulon sphacelatum, an Australian Aboriginal medicine. Journal of Ethnopharmacology, 68(1-3), 283-288. DOI Scopus71 WoS47 Europe PMC19
  1998	Pearce, W., Pyke, S., & Tiekink, E. (1998). Crystal structure of ethyl 3,3-dimethyl-5,7-dihydro-H[1,3]dioxepino[5,6-c]=pyrrole-6-carboxylate, C12H17NO4. Zeitschrift fur Kristallographie, 213(1-4), 61-62. DOI Scopus1 WoS1
  1998	Creaser, S. P., Lincoln, S. F., Pyke, S. M., & Tiekink, E. R. T. (1998). Crystal structure of 1,4,7-triazabicyclo[4.3.0]non-6-ene-5-one, C<inf>6</inf>H<inf>9</inf>N<inf>3</inf>O. Zeitschrift fur Kristallographie - New Crystal Structures, 213(1-4), 41. DOI Scopus1
  1998	Kosovel, F. J., Pyke, S. M., & Tiekink, E. R. T. (1998). Redetermination of the crystal structure of 5-methyl-2-thiocytosine hemihydrate, C<inf>5</inf>H<inf>7</inf>N<inf>3</inf>S 0.5H<inf>2</inf>O, at 213 K. Zeitschrift fur Kristallographie - New Crystal Structures, 213(1-4), 40. DOI
  1998	Creaser, S., Lincoln, S., Pyke, S., & Tiekink, E. (1998). Crystal structure of 1,4,7-triazabicyclo[4.3.0]non-6-ene-5-one, C6H9N3O. Zeitschrift fur Kristallographie, 213(1), 41. WoS1
  1998	Kosovel, F., Pyke, S., & Tiekink, E. (1998). Redetermination of the crystal structure of 5-methyl-2-thiocytosine hemihydrate, C5H7N3S 0.5H2O, at 213K. Zeitschrift fur Kristallographie, 213(1), 40.
  1996	Tiekink, E., Creaser, S., & Pyke, S. (1996). Crystal structure of 3,3-dimethyl-1,5-dioxa-9-thiaspiro[5.5]-undecane-9-oxide,9-N-[(4-methyl-benzenesulfonyl)imine], C17H25NO5S2. Zeitschrift fur Kristallographie, 211(8), 573-574. DOI
  1996	Tiekink, E., Pearce, W., & Pyke, S. (1996). Crystal structure of (3R*,4R*) 3-iodi-4-(4'-methylbenzenesulfonyl)oxolane, C11H13IO3S. Zeitschrift fur Kristallographie, 211(6), 421-422. DOI
  1996	Tiekink, E., Basu Baul, T., Pyke, S., & Sarma, K. (1996). Crystal and molecular structure of aquatriphenyltin 2-(3-formyl-4-hydroxyphenylazo) benzoate. Main Group Metal Chemistry, 19(12), 807-814. DOI Scopus31 WoS29
  1996	Pyke, S., Graham, A., Loughlin, W., Moore, M., Wilson, G., & Taylor, R. (1996). The generation and synthetic applications of episulfone α-anions. Journal of the Chemical Society, Perkin Transactions 1, (7), 661-667. DOI Scopus14 WoS13
  1994	Guo, Z. X., Haines, A. H., Pyke, S. M., Pyke, S. G., & Taylor, R. J. K. (1994). Improved preparation of (±)-(1,3/2,4)-5-cyclohexene-1,2,3,4-tetrol [(±)-conduritol-B] and its reaction with hydrobromic and hydrochloric acid; synthesis and characterisation of some (±)-1-deoxy-1-halo- and (±)-1,4-dideoxy-1,4-dihaloconduritols. Carbohydrate Research, 264(1), 147-153. DOI Scopus29 WoS30 Europe PMC6
  1993	EWIN, R. A., LOUGHLIN, W. A., PYKE, S. M., MORALES, J. C., & TAYLOR, R. J. K. (1993). THE ISOLATION OF EPISULFONES FROM THE RAMBERG-BACKLUND REARRANGEMENT .3.. SYNLETT, 1993(9), 660-662. DOI WoS10
  1993	Jeffery, S. M., Sutherland, A. G., Pyke, S. M., Powell, A. K., & Taylor, R. J. K. (1993). Isolation of episulfones from the Ramberg-Bäcklund rearrangement. Part 2. X-ray molecular structure of 2,3-epithio-8,8-dimethyl-6,10- dioxaspiro[4.5]-decane S,S-dioxide and of r-6-benzyl-t-7,t-8-epithio-1,4- dioxaspiro[4.4]nonane S,S-dioxide. Journal of the Chemical Society, Perkin Transactions 1, (19), 2317-2327. DOI Scopus25 WoS19
  1991	Crossley, M. J., Burn, P. L., Langford, S. J., Pyke, S. M., & Stark, A. G. (1991). A new method for the synthesis of porphyrin-α-diones that is applicable to the synthesis of trans-annular extended porphyrin systems. Journal of the Chemical Society, Chemical Communications, (21), 1567-1568. DOI Scopus95 WoS89
  1987	Crossley, M. J., King, L. G., & Pyke, S. M. (1987). A new and highly efficient synthesis of hydroxyporphyrins. Tetrahedron, 43(20), 4569-4577. DOI Scopus67 WoS64

• Book Chapters

  Year	Citation
  2022	Swan, E., Jayne, S., & Pyke, S. (2022). Recent Developments in Targeting "Undruggable" SH3 Domains. In J. Bronson, B. Savall, & R. Hudkins (Eds.), 2021 Medicinal Chemistry Reviews (Vol. 56, pp. 389-411). American Chemical Society.
  2016	Schmid, S., Schultz, M., Priest, S., O'Brien, G., Pyke, S., Bridgeman, A., . . . Jamie, I. (2016). Assessing the assessments: Development of a tool to evaluate assessment items in chemistry according to learning outcomes. In M. Schultz, S. Schmid, & T. Holme (Eds.), Technology and Assessment Strategies for Improving Student Learning in Chemistry (Vol. 1235, 1 ed., pp. 225-244). Washington: American Chemical Society. DOI Scopus4 WoS2
  2008	Taylor, R. J. K., Pyke, S. G., & Pyke, S. M. (2008). Natural products containing the cyclopentane sub-unit: Prostaglandins. In Second Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds: A Modern Comprehensive Treatise (Vol. 2, pp. 221-282). DOI Scopus4
  1991	Taylor, R. J. K., Pyke, S. G., & Pyke, S. M. (1991). Natural products containing the cyclopentane sub-unit. In Second Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds (pp. 221-282). Elsevier. DOI

• Conference Papers

  Year	Citation
  2014	Priest, S. J., Williamson, N. M., & Pyke, S. M. (2014). Capabilities and Limitations of the Advancing Science by Enhancing Learning in the Laboratory Project Student Learning Evaluation Data. In Proceedings of the RACI National Congress. Adelaide.
  2012	Williamson, N. M., Huang, D. M., Pyke, S. M., Willison, J., & Metha, G. F. (2012). Constructing a First Year University Chemistry Course for the ‘Late Bloomers’. In ERGA 2012 Proceedings. Adelaide.
  2012	Priest, S. J., Pyke, S. M., Williamson, N. M., & Willison, J. (2012). Representations of Scientific Concepts and Learning Experience of First Year Undergraduate Students. In ERGA 2012 Proceedings. Adelaide.
  2010	Barrie, S. C., Buntine, M. A., da Silva, K. B., Lim, K., Pyke, S., Sharma, M., . . . Kable, S. H. (2010). Improving student engagement in the laboratory: An initiative across all Australian universities. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 240 (pp. 1 page). AMER CHEMICAL SOC.
  2010	Pyke, S. (2010). An initiative in introducing iPads to higher education. In The Education Research Group of Adelaid (pp. The Changing Face of Education, 24-25 September, 2010). Adelaide, Australia.
  1995	Cooper, M. A., Pyke, S. M., & Ward, A. D. (1995). Unusually stable hydrates of N-substituted 3-hydroxy-2-(phenylselenenyl)methylpiperidine derivatives. Where is the water? An NMR study.. In D. G. Gorenstein (Ed.), BULLETIN OF MAGNETIC RESONANCE, VOL 17, NOS 1-4, DECEMBER 1995 (pp. 244-245). SYDNEY, AUSTRALIA: INT SOC MAGNETIC RESONANCE.

• Conference Items

  Year	Citation
  2015	Pyke, S. M., Porter-Dabrowski, C., & Williamson, N. M. (2015). Student Attitudes and Approaches to Learning Chemistry: What Influences Academic Success?. Poster session presented at the meeting of Proceedings of the Australian Conference on Science and Mathematics Education. Perth.
  2014	Pyke, S. M., Porter-Dabrowski, C., & Williamson, N. M. (2014). Impact of Student Approaches to Learning on Both Their Experience and Their Performance in Problem Solving Workshop Classes: A Pilot Study. Poster session presented at the meeting of Proceedings of the Australian Conference on Science and Mathematics Education. Sydney.
  2012	Priest, S. J., Williamson, N. M., & Pyke, S. M. (2012). Thinking Beyond the Macro Domain of Chemistry in First Year Undergraduate Students. Poster session presented at the meeting of Poceedings of Chem Ed 2012. Adelaide.
  2012	Priest, S. J., Pyke, S. M., Williamson, N. M., & Willison, J. (2012). Using Laboratory Experiences to Investigate Learning Trends in Chemistry. Poster session presented at the meeting of Proceedings of the Australian Conference on Science and Mathematics Educatio. Sydney.

• Patents

  Year	Citation
  2003	Booker, G., Pyke, S., Branson, K., & Inglis, S. (2003). PCT/AU2002/001064, SH3 Protein Domains and their Ligands. Australia.

Simon has been the Program Coordinator for the Bachelor of Science since 2007 and made substantial contributions to the design of the Bachelor of Science (Advanced) program launched in 2011 (he was the inaugural Program Coordinator). He designed, developed and delivered the core course 'Principles & Practice of Science I' (2011-2016) which focused on development of core academic skills for students in the Bachelor of Science and Bachelor of Science (Advanced) programs, and introduced these students to what it means to 'be a scientist'. In addition, Simon also teaches Chemistry courses from 1st year to Honours level. The quality of his teaching has been recognised by numerous awards at institutional. state and national levels.

• Current Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2021	Co-Supervisor	Characterisation of Snake Venom Proteins to Inform New Advances in Biotechnology	Doctor of Philosophy	Doctorate	Full Time	Mr Lewis Owen McFarlane
  2020	Principal Supervisor	The interplay between alternative conceptions in stoichiometry and proportionality: Does mathematical aptitude impact chemistry capability?	Doctor of Philosophy	Doctorate	Full Time	Miss Kylie Quynh Do
  2019	Principal Supervisor	Investigating the Attitudes of Primary School Teachers Towards Science and Mathematics	Doctor of Philosophy	Doctorate	Part Time	Miss Thao Hong Duong

• Past Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2019 - 2023	Principal Supervisor	Development of 2-Aminoquinoline Derivatives with Improved Drug-Like Character as Small Molecule Inhibitors for a Protein-Protein Interaction Domain	Doctor of Philosophy	Doctorate	Part Time	Ms Ellen Lillian Swan
  2019 - 2023	Co-Supervisor	Understanding cytochrome P450 cholesterol metabolism in bacteria	Doctor of Philosophy	Doctorate	Full Time	Dr Amna Jamal Saad Mohamed Ghith
  2018 - 2023	Principal Supervisor	Wild Nicotiana: Profiling the Alkaloids of Australian Species	Doctor of Philosophy	Doctorate	Full Time	Ms Samantha Dama
  2018 - 2020	Co-Supervisor	Exploring the Monooxygenase Activity and Selectivity of Two Related Cytochrome P450 Enzymes	Master of Philosophy	Master	Full Time	Mr Saurabh Kumar Ahirwar
  2018 - 2020	Principal Supervisor	Synthesis and Network Analysis of Substituted Bullvalenes and the Total Synthesis of Endiandric Acid J and Beilcyclone A	Doctor of Philosophy	Doctorate	Full Time	Mr Ossama Yahiaoui
  2018 - 2022	Co-Supervisor	Synthesis and Applications of Substituted Bullvalenes and The Synthesis of Bicyclo[4.2.0]octadiene Derived Natural Products	Doctor of Philosophy	Doctorate	Full Time	Mr Harshal Deepak Patel
  2017 - 2021	Principal Supervisor	Assessing the Validity of Multiple-Choice Questions, Using them to undertake Comparative Analysis on Student Cohort Performance, and Evaluating the Methodologies Used	Doctor of Philosophy	Doctorate	Full Time	Mr Jacob Rhys Marchant
  2017 - 2021	Co-Supervisor	The Synthesis of Chromane Meroterpenoids via Biomimetic Cascade Reactions	Doctor of Philosophy	Doctorate	Full Time	Mr Aaron John Day
  2017 - 2021	Co-Supervisor	The Total Synthesis of Natural Products via Cascade Reactions	Doctor of Philosophy	Doctorate	Full Time	Miss Laura Jane Burchill
  2015 - 2019	Co-Supervisor	Application of the Monooxygenase Enzymes CYP101B1 and CYP101C1 from Novosphingobium aromaticivorans for Selective and Efficient Functionalisation of Inert C-H Bonds	Doctor of Philosophy	Doctorate	Full Time	Mr Md Raihan Sarkar
  2015 - 2019	Principal Supervisor	Pretty Keen for a Protein: Development of Small Molecule Inhibitors for a Protein-Protein Interaction Domain	Doctor of Philosophy	Doctorate	Full Time	Miss Stephanie Jayne
  2014 - 2018	Co-Supervisor	Deciphering Electron Transfer and Cytochrome P450 Activity in Mycobacterium marinum	Doctor of Philosophy	Doctorate	Full Time	Ms Stella Agnes Child
  2014 - 2016	Principal Supervisor	Investigations and Applications of Self-Sufficient Cytochrome P450 Monooxygenases	Master of Philosophy	Master	Full Time	Mr Samuel Munday
  2012 - 2017	Principal Supervisor	Valid Measurement of Laboratory Learning Experience Quality from the Student Perspective	Doctor of Philosophy	Doctorate	Part Time	Samuel James Priest
  2012 - 2013	Co-Supervisor	Aspects of Organoselenium Chemistry	Doctor of Philosophy	Doctorate	Part Time	Ms Virginia Ward
  2011 - 2016	Principal Supervisor	Investigation of a Novel Toxin Produced By A Limnothrix Cyanobacteria	Doctor of Philosophy	Doctorate	Full Time	Dr Faye Titania Whan
  2007 - 2009	Principal Supervisor	Isolation, Structural Elucidation and Antibacterial Activity of the Chemical Constituents of Scaevola Spinescens	Master of Science	Master	Full Time	Miss Michele Mejin
  2006 - 2009	Principal Supervisor	Development of 2-Aminoquinoline Derivatives as Ligands for Tec SH3 Domain	Doctor of Philosophy	Doctorate	Full Time	Mrs Jessica Smith
  2005 - 2013	Co-Supervisor	Structure-function Studies and In Silico Drug Discovery Targeting the Liver Oncoprotein Gankyrin	Doctor of Philosophy	Doctorate	Full Time	Mr Iain Murchland
  2004 - 2008	Principal Supervisor	Investigating 2-Aminoquinoline Derivatives as Small Molecule Ligands for the Tec SH3 Domain	Doctor of Philosophy	Doctorate	Full Time	Miss Rhiannon Jones
  2003 - 2011	Co-Supervisor	Studies in Molecular, Supramolecular and Macromolecular Design	Doctor of Philosophy	Doctorate	Full Time	Mr Oscar Archer
  2003 - 2006	Co-Supervisor	Negative Ion Mass Spectrometry of Peptides An Aid to Structure Determination	Doctor of Philosophy	Doctorate	Full Time	Dr Daniel Bilusich
  2003 - 2006	Co-Supervisor	Amphibian Neuropeptides: Isolation, Sequence Determination and Bioactivity	Doctor of Philosophy	Doctorate	Full Time	Ms Vita Maselli
  2001 - 2005	Co-Supervisor	Development of Small-Molecule Ligands for SH3 Protein Domains	Doctor of Philosophy	Doctorate	Full Time	Mr Steven Inglis
  2001 - 2004	Co-Supervisor	PROTECTION AGAINST a,b-UNSATURATED ALDEHYDE TOXICITY BY HYDRAZINOPHTHALAZINE COMPOUNDS.	Doctor of Philosophy	Doctorate	Full Time	Ms Lisa Kaminskas

• Committee Memberships

  Date	Role	Committee	Institution	Country
  2015 - ongoing	Member	Academic Board	University of Adelaide	Australia
  2012 - 2013	Chair	Chemistry Threshold Learning Outcomes Working Party	ChemNet (Office of Learning & Teaching)	Australia
  2011 - ongoing	Member	Quality Assurance Integrity Panel	SACE Board of South Australia	Australia
  2011 - 2013	Member	Science & Mathematics Network (SaNnet) Steering Committee	SaMnet (Office of Learning & Teaching)	Australia
  2009 - 2011	Member	Learning & Teaching Academic Standards Advisory Group (Science)	Australian Learning & Teaching Council	Australia
  2008 - ongoing	Member	Accreditation, Recognition & Certification Committee	SACE Board of South Australia	Australia
  2006 - ongoing	Member	University Learning Committee	University of Adelaide	Australia
  2006 - ongoing	Member	Program Approval & Entry Committee	University of Adelaide	Australia

• Memberships

  Date	Role	Membership	Country
  1995 - 2010	Member	Australian & New Zealand Society for Magnetic Resonance	Australia
  1990 - ongoing	Member	Royal Society of Chemistry	United Kingdom
  1984 - ongoing	Member	Royal Australian Chemical Institute	-

• Position: Professor
• Phone: 83135358
• Email: simon.pyke@adelaide.edu.au
• Fax: 83134380
• Campus: North Terrace
• Building: Badger, floor 2
• Org Unit: Chemistry